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Nick Bown

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Fathi Azribi; Albiruni Ryan Abdul Razak; Georgina Bough; Daniela Lee; David Rowe; Nick Bown; Petra Dildey; Stephen Clark; Ruth Plummer
Extraosseous pericardial Ewing's sarcoma.
Paul Roberts; Susan A Burchill; Samantha Brownhill; Catherine Cullinane; Colin Johnston; Mike J Griffiths; Dom J McMullan; Nick Bown; Stephen P Morris; Ian J Lewis
Ploidy and karyotype complexity are powerful prognostic indicators in the Ewing's sarcoma family of tumors: a study by the United Kingdom Cancer Cytogenetics and the Children's Cancer and Leukaemia Group.
Mary A Slatter; Kenneth L Brigham; Anne M Dickinson; Helen L Harvey; D Barge; A Jackson; Nick Bown; Terence J Flood; Andrew J Cant; Mario Abinun; Andrew R Gennery
Long-term immune reconstitution after anti-CD52-treated or anti-CD34-treated hematopoietic stem cell transplantation for severe T-lymphocyte immunodeficiency.

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All Publications

2010: Fathi Azribi; Albiruni Ryan Abdul Razak; Georgina Bough; Daniela Lee; David Rowe; Nick Bown; Petra Dildey; Stephen Clark; Ruth Plummer
Extraosseous pericardial Ewing's sarcoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(4):e48-50.
2008: Paul Roberts; Susan A Burchill; Samantha Brownhill; Catherine Cullinane; Colin Johnston; Mike J Griffiths; Dom J McMullan; Nick Bown; Stephen P Morris; Ian J Lewis
Ploidy and karyotype complexity are powerful prognostic indicators in the Ewing's sarcoma family of tumors: a study by the United Kingdom Cancer Cytogenetics and the Children's Cancer and Leukaemia Group.
Genes, chromosomes & cancer 2008;47(3):207-20.
2008: Mary A Slatter; Kenneth L Brigham; Anne M Dickinson; Helen L Harvey; D Barge; A Jackson; Nick Bown; Terence J Flood; Andrew J Cant; Mario Abinun; Andrew R Gennery
Long-term immune reconstitution after anti-CD52-treated or anti-CD34-treated hematopoietic stem cell transplantation for severe T-lymphocyte immunodeficiency.
The Journal of allergy and clinical immunology 2008;121(2):361-7.
2007: Danny Routledge; Antony Jackson; David Bourn; Nick Bown; Michael Cole; Mary A Slatter; Andrew R Gennery; Ann Curtis
Quantitative assessment of mixed chimerism in allogeneic stem cell transplant patients: a comparison of molecular genetic and cytogenetic approaches.
Journal of pediatric hematology/oncology 2007;29(6):428-31.
2006: R N Sanderson; P R E Johnson; A V Moorman; E Roman; Eleanor V Willett; P R Taylor; Stephen J Proctor; Nick Bown; S Ogston; David T Bowen
Population-based demographic study of karyotypes in 1709 patients with adult acute myeloid leukemia.
Leukemia 2006;20(3):444-50.
2005: M Griffiths; J Mason; M Rindl; S Akiki; Dominic J McMullan; V Stinton; H Powell; Ann Curtis; Nick Bown; Charles Craddock
Acquired isodisomy for chromosome 13 is common in AML, and associated with FLT3-itd mutations.
Leukemia 2005;19(12):2355-8.
2005: Jo Vandesompele; Baudis Michael; Katleen De Preter; Nadine Van Roy; Peter F Ambros; Nick Bown; Christian Brinkschmidt; Holger Christiansen; Valérie Combaret; Maria Lastowska; James Nicholson; Anne O'Meara; Dominique Plantaz; Raymond L Stallings; Bénédicte Brichard; Caroline Van den Broecke; Sylvia De Bie; Anne De Paepe; Geneviève Laureys; Frank Speleman
Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(10):2280-99.
2005: Helen Powell; Ann Curtis; Nick Bown; Penny Taylor
No correlation between trisomy 13 and FLT3 duplication in acute myeloid leukemia.
Cancer genetics and cytogenetics 2005;156(1):92-3.
2003: Daniel Satgé; Samuel W Moore; Charles A Stiller; Félix K Niggli; Kathy Pritchard-Jones; Nick Bown; Jean Bénard; Dominique Plantaz
Abnormal constitutional karyotypes in patients with neuroblastoma: a report of four new cases and review of 47 others in the literature.
Cancer genetics and cytogenetics 2003;147(2):89-98.
2003: Brian J P Huntly; françois guilhot; Alistair G Reid; George S Vassiliou; Evelin Hennig; Christina Franke; Jennie Byrne; Andre Brizard; Dietger Niederwieser; Julie Freeman-Edward; Gavin Cuthbert; Nick Bown; Richard E Clark; Elisabeth P Nacheva; Anthony R Green; Michael W N Deininger
Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions.
Blood 2003;102(6):2205-12.
2002: Mark R Velangi; Michael M Reid; Nick Bown; Graham H Jackson; Geoffrey P Summerfield; Stephen J Proctor; P R A Taylor
Acute lymphoblastic leukaemia of the L3 subtype in adults in the Northern health region of England 1983-99.
Journal of clinical pathology 2002;55(8):591-5.
2002: David Rowe; Nick Bown
Diagnostic detection of AML1/ETO gene fusion by polymerase chain reaction.
Leukemia 2002;16(8):1576-7; author reply 1577.
2002: Maria Łastowska; Simon J Cotterill; Nick Bown; Catherine Cullinane; Sadick Variend; John Lunec; Tom Strachan; Andrew D J Pearson; Michael S Jackson
Breakpoint position on 17q identifies the most aggressive neuroblastoma tumors.
Genes, chromosomes & cancer 2002;34(4):428-36.
2002: David Rowe; Gareth J Breese; Anne L Lennard; Nick Bown
Late-appearing MLL rearrangement arising as a secondary change in adult acute myeloid leukemia.
Genes, chromosomes & cancer 2002;34(1):126-8.
2002: Alistair G Reid; Brian J P Huntly; Eveline Hennig; Dietger Niederwieser; Lynda J Campbell; Nick Bown; Nick Telford; Helen Walker; Colin Grace; Michael W N Deininger; Anthony R Green; Elisabeth P Nacheva
Deletions of the derivative chromosome 9 do not account for the poor prognosis associated with Philadelphia-positive acute lymphoblastic leukemia.
Blood 2002;99(6):2274-5.
2002: Nick Bown; Simon J Cotterill; Paul Roberts; Mike Griffiths; Simon Larkins; Steve Hibbert; Helen Middleton; Anna Kelsey; Denise Tritton; Chris Mitchell
Cytogenetic abnormalities and clinical outcome in Wilms tumor: a study by the U.K. cancer cytogenetics group and the U.K. Children's Cancer Study Group.
Medical and pediatric oncology 2002;38(1):11-21.
2001: Nick Bown
Neuroblastoma tumour genetics: clinical and biological aspects.
Journal of clinical pathology 2001;54(12):897-910.
2001: A W Wells; Nick Bown; Michael M Reid; PJ Hamilton; Graham H Jackson; Penelope R A Taylor
Erythroleukaemia in the north of England: a population based study.
Journal of clinical pathology 2001;54(8):608-12.
2001: Maria Lastowska; Catherine Cullinane; Sadick Variend; Simon J Cotterill; Nick Bown; S O'Neill; K Mazzocco; Paul Roberts; James Nicholson; Caroline Ellershaw; Andrew D J Pearson; Michael S Jackson
Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(12):3080-90.
2001: D Plantaz; Jo Vandesompele; Nadine Van Roy; Maria Lastowska; Nick Bown; Valérie Combaret; M C Favrot; O Delattre; J Michon; Jean Bénard; O Hartmann; JC Nicholson; Fiona M Ross; Christian Brinkschmidt; Geneviève Laureys; H Caron; K K Matthay; Burt Feuerstein; Frank Speleman
Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lacking MYCN amplification.
International journal of cancer. Journal international du cancer 2001;91(5):680-6.
2001: Jo Vandesompele; Frank Speleman; Nadine Van Roy; Geneviève Laureys; C Brinskchmidt; Holger Christiansen; F Lampert; Maria Lastowska; Nick Bown; A Pearson; JC Nicholson; F Ross; Valérie Combaret; O Delattre; Burt Feuerstein; Dominique Plantaz
Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: how many genetic subgroups are there?
Medical and pediatric oncology 2001;36(1):5-10.
2001: Maria Lastowska; Nadine Van Roy; Nick Bown; Frank Speleman; Paul Roberts; John Lunec; Tom Strachan; Andrew D J Pearson; Michael S Jackson
Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma.
Medical and pediatric oncology 2001;36(1):20-3.
2001: Nick Bown; Maria Lastowska; Simon J Cotterill; S O'Neill; Caroline Ellershaw; Paul Roberts; Ian Lewis; Andrew D J Pearson
17q gain in neuroblastoma predicts adverse clinical outcome. U.K. Cancer Cytogenetics Group and the U.K. Children's Cancer Study Group.
Medical and pediatric oncology 2001;36(1):14-9.
2001: S O'Neill; L Ekstrom; Maria Lastowska; Paul Roberts; G M Brodeur; Ursula R Kees; M Schwab; Nick Bown
MYCN amplification and 17q in neuroblastoma: evidence for structural association.
Genes, chromosomes & cancer 2001;30(1):87-90.
2000: David Rowe; Simon J Cotterill; Fiona M Ross; D J Bunyan; S J Vickers; J Bryon; Dominic J McMullan; M J Griffiths; John T Reilly; Elisabeth A Vandenberghe; G Wilson; Ann Watmore; Nick Bown
Cytogenetically cryptic AML1-ETO and CBF beta-MYH11 gene rearrangements: incidence in 412 cases of acute myeloid leukaemia.
British journal of haematology 2000;111(4):1051-6.
2000: Gavin Cuthbert; K Thompson; S McCullough; Ann Watmore; Ho Dickinson; Nick Telford; F Mugneret; C Harrison; M Griffiths; Nick Bown
MLL amplification in acute leukaemia: a United Kingdom Cancer Cytogenetics Group (UKCCG) study.
Leukemia 2000;14(11):1885-91.
2000: Gavin Cuthbert; K Thompson; Gareth J Breese; S McCullough; Nick Bown
Sensitivity of FISH in detection of MLL translocations.
Genes, chromosomes & cancer 2000;29(2):180-5.
2000: J Freeman-Edward; S O'Neill; Maria Lastowska; Nick Bown
Expulsion of amplified MYCN from neuroblastoma tumor cells.
Cancer genetics and cytogenetics 2000;116(1):87-8.
1999: Nick Bown; Simon J Cotterill; Maria Lastowska; S O'Neill; Andrew D J Pearson; Dominique Plantaz; Mounira Meddeb; Gisèle Danglot; Christian Brinkschmidt; Holger Christiansen; Geneviève Laureys; Frank Speleman; James Nicholson; Alain BERNHEIM; D R Betts; Jo Vandesompele; Nadine Van Roy
Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma.
The New England journal of medicine 1999;340(25):1954-61.
1999: Gavin Cuthbert; S McCullough; R Finney; Gareth J Breese; Nick Bown
Jumping translocation at 11q23 with MLL gene rearrangement and interstitial telomeric sequences.
Genes, chromosomes & cancer 1999;24(4):295-8.
1998: Maria Lastowska; Nadine Van Roy; Nick Bown; Frank Speleman; John Lunec; Tom Strachan; Andrew D J Pearson; Michael S Jackson
Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines.
Genes, chromosomes & cancer 1998;23(2):116-22.
1997: Maria Lastowska; Simon J Cotterill; Andrew D J Pearson; Paul Roberts; AG McGuckin; Ian Lewis; Nick Bown
Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patients. U.K. Children's Cancer Study Group and the U.K. Cancer Cytogenetics Group.
European journal of cancer (Oxford, England : 1990) 1997;33(10):1627-33.
1997: Nick Bown; David Rowe; Michael M Reid
Granulocytic sarcoma with translocation (9;11)(p22;q23): two cases.
Cancer genetics and cytogenetics 1997;96(2):115-7.
1997: Maria Lastowska; Paul Roberts; Andrew D J Pearson; Ian Lewis; John Wolstenholme; Nick Bown
Promiscuous translocations of chromosome arm 17q in human neuroblastomas.
Genes, chromosomes & cancer 1997;19(3):143-9.
1997: Maria Lastowska; Elisabeth P Nacheva; AG McGuckin; Ann Curtis; Colin Grace; A Pearson; Nick Bown
Comparative genomic hybridization study of primary neuroblastoma tumors. United Kingdom Children's Cancer Study Group.
Genes, chromosomes & cancer 1997;18(3):162-9.
1995: Stephen J Proctor; Penelope R A Taylor; A Stark; P J Carey; Nick Bown; PJ Hamilton; Michael M Reid
Evaluation of the impact of allogenic transplant in first remission on an unselected population of patients with acute myeloid leukaemia aged 15-55 years. The Northern Regional Haematology Group.
Leukemia 1995;9(7):1246-51.
1995: S Murray Yule; Nick Bown; A J Malcolm; Michael M Reid; Andrew D J Pearson
Solid alveolar rhabdomyosarcoma with a t(2;13).
Cancer genetics and cytogenetics 1995;80(2):107-9.
1995: Penelope R A Taylor; Michael M Reid; A N Stark; Nick Bown; PJ Hamilton; Stephen J Proctor
De novo acute myeloid leukaemia in patients over 55-years-old: a population-based study of incidence, treatment and outcome. Northern Region Haematology Group.
Leukemia 1995;9(2):231-7.
1994: J A Latham; Nick Bown; G Cain; P Middleton; J Kernahan; K Windebank; Michael M Reid
Molecular heterogeneity of variant Philadelphia translocations in childhood acute lymphoblastic leukaemia.
Leukemia 1994;8(2):292-4.
1994: Nick Bown; Michael M Reid; AJ Malcolm; E V Davison; Alan W Craft; Andrew D J Pearson
Cytogenetic abnormalities of small round cell tumours.
Medical and pediatric oncology 1994;23(2):124-9.
1993: Z T Maung; Nick Bown; PJ Hamilton
Collagenase digestion of bone marrow trephine biopsy specimens: an important adjunct to haematological diagnosis when marrow aspiration fails.
Journal of clinical pathology 1993;46(6):576-7.
1993: Graham H Jackson; P J Carey; A J Cant; Nick Bown; Michael M Reid
Myelodysplastic syndromes in children.
British journal of haematology 1993;84(1):185-6.
1992: P R Taylor; M M Reid; Nick Bown; PJ Hamilton; Stephen J Proctor
Acute lymphoblastic leukemia in patients aged 60 years and over: a population-based study of incidence and outcome.
Blood 1992;80(7):1813-7.
1992: Michael M Reid; P W Saunders; Nick Bown; Carol R Bradford; Z T Maung; A W Craft; AJ Malcolm
Alveolar rhabdomyosarcoma infiltrating bone marrow at presentation: the value to diagnosis of bone marrow trephine biopsy specimens.
Journal of clinical pathology 1992;45(9):759-62.
1992: Nick Bown
Chromosome studies of solid tumours.
Journal of clinical pathology 1992;45(7):556-60.
1992: Nick Bown; S Murray Yule; J Evans; J Kernahan; Michael M Reid
Chronic myelomonocytic leukemia with t(13;14) in a child.
Cancer genetics and cytogenetics 1992;60(2):190-2.
1992: Graham H Jackson; P Middleton; R Prince; Nick Bown; J Kernahan; Michael M Reid
Philadelphia positive acute leukaemia with minor breakpoint cluster rearrangement may be a stem cell disease.
British journal of haematology 1992;81(1):77-80.
1991: Anne L Lennard; Graham H Jackson; P J Carey; Nick Bown; P Middleton; Stephen J Proctor
Secondary acute lymphoblastic leukaemia with 4:11 translocation following treatment for Hodgkin's disease: case report and review of the literature.
Leukemia 1991;5(7):624-7.
1989: Michael M Reid; E V Davison; Nick Bown
Trisomy 11 in acute lymphoblastic leukaemia.
Journal of clinical pathology 1989;42(5):555-6.
1988: Nick Bown; Andrew D J Pearson; E V Davison; D Gardner-Medwin; P Crawford; Robert H Perry
Multiple chromosome rearrangements in a childhood ependymoma.
Cancer genetics and cytogenetics 1988;36(1):25-30.
1988: Andrew D J Pearson; Michael M Reid; E V Davison; Nick Bown; AJ Malcolm; Alan W Craft
Cytogenetic investigations of solid tumours of children.
Archives of disease in childhood 1988;63(9):1012-5.
1988: Nick Bown; E V Davison; Andrew D J Pearson; AJ Malcolm
Cytogenetic abnormalities in a primitive neuroectodermal tumor.
Cancer genetics and cytogenetics 1988;32(2):247-52.
1987: Nick Bown; Michael M Reid; Andrew D J Pearson; E V Davison; AJ Malcolm; Alan W Craft
Cytogenic investigations in the assessment of response to treatment in neuroblastoma.
Journal of clinical pathology 1987;40(11):1334-6.
1986: Nick Bown; I Cross; E V Davison; J Burn
Partial trisomy 20p resulting from a recombination of a familial pericentric inversion.
Human genetics 1986;74(4):417-9.
1986: Nick Bown; H Daly; E V Davison; H Lloyd
t(9;11)(p22;q24) in a patient with acute monocytic leukemia.
Cancer genetics and cytogenetics 1986;23(2):179-81.