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Henri Versteeg

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Huma Safdar; Daniela Salvatori; Ka Lei Cheung; El Houari Laghmani; Pieter H Reitsma; Henri H Versteeg; Gerry T M Wagenaar; Bart J M van Vlijmen
Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production.
Lisa G van den Hengel; A Q M Jeanne van Steijn-van Tol; Henri H Versteeg; Rogier M Bertina; Susanne Osanto
Microparticle-associated tissue factor activity in plasma is unaffected by cytolytic chemotherapy treatment in metastatic testicular cancer patients.
Lisa G van den Hengel; Annemarie M van Oeveren-Rietdijk; Anton-Jan van Zonneveld; Henri H Versteeg; Hetty C de Boer; Margreet R De Vries; Jaap F Hamming; Alwine A Hellingman; Anne Yael Nossent; Pieter H Reitsma; C Arnold Spek; Paul H A Quax
Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model.

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All Publications

2013: Huma Safdar; Daniela Salvatori; Ka Lei Cheung; El Houari Laghmani; Pieter H Reitsma; Henri H Versteeg; Gerry T M Wagenaar; Bart J M van Vlijmen
Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production.
Blood 2013;121(21):4413-6.
2013: Lisa G van den Hengel; A Q M Jeanne van Steijn-van Tol; Henri H Versteeg; Rogier M Bertina; Susanne Osanto
Microparticle-associated tissue factor activity in plasma is unaffected by cytolytic chemotherapy treatment in metastatic testicular cancer patients.
Thrombosis research 2013;131(2):187-9.
2013: Lisa G van den Hengel; Annemarie M van Oeveren-Rietdijk; Anton-Jan van Zonneveld; Henri H Versteeg; Hetty C de Boer; Margreet R De Vries; Jaap F Hamming; Alwine A Hellingman; Anne Yael Nossent; Pieter H Reitsma; C Arnold Spek; Paul H A Quax
Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model.
PloS one 2013;8(4):e61923.
2013: Henri H Versteeg; Johan W M Heemskerk; Marcel Levi; Pieter H Reitsma
New fundamentals in hemostasis.
Physiological reviews 2013;93(1):327-58.
2013: Lisa G van den Hengel; Susanne Osanto; Pieter H Reitsma; Henri H Versteeg
Murine tissue factor coagulant activity is critically dependent on the presence of an intact allosteric disulfide.
Haematologica 2013;98(1):153-8.
2012: Begüm Kocatürk; Henri H Versteeg
Tissue factor isoforms in cancer and coagulation: may the best isoform win.
Thrombosis research 2012;129 Suppl 1():S69-75.
2012: Pieter H Reitsma; Henri H Versteeg; Saskia Middeldorp
Mechanistic view of risk factors for venous thromboembolism.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(3):563-8.
2012: Yascha W van den Berg; Susanne Osanto; Pieter H Reitsma; Henri H Versteeg
The relationship between tissue factor and cancer progression: insights from bench and bedside.
Blood 2012;119(4):924-32.
2012: Richard C Godby; David Y Hui; Stephen F Konieczny; Evgeny Ozhegov; Wolfram Ruf; Ramprasad Srinivasan; Robert Sturm; Yascha W Van Den Berg; Henri H Versteeg; Bruce J Aronow; Vladimir Y Bogdanov
Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models.
Molecular medicine (Cambridge, Mass.) 2012;18():771-9.
2012: L G van den Hengel; M H A Bos; P H Reitsma; Y W van den Berg; Henri H Versteeg
Evolutionary conservation of the tissue factor disulfide bonds and identification of a possible oxidoreductase binding motif.
Journal of thrombosis and haemostasis : JTH 2012;10(1):161-2.
2011: Lisa G van den Hengel; Begüm Kocatürk; Pieter H Reitsma; Wolfram Ruf; Henri H Versteeg
Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor.
Blood 2011;118(12):3446-8.
2011: Henri H Versteeg; Wolfram Ruf
Thiol pathways in the regulation of tissue factor prothrombotic activity.
Current opinion in hematology 2011;18(5):343-8.
2011: Karla C S Queiroz; Joris J T H Roelofs; Hella L Aberson; Janwillem Duitman; Angelique P Groot; Anje A Te Velde; Yascha Van Den Berg; Cornelis van 't Veer; Henri H Versteeg; Marleen I Verstege; C Arnold Spek
Tissue factor-dependent chemokine production aggravates experimental colitis.
Molecular medicine (Cambridge, Mass.) 2011;17(9-10):1119-26.
2011: Lisa G van den Hengel; Henri H Versteeg
Tissue factor signaling: a multi-faceted function in biological processes.
Frontiers in bioscience (Scholar edition) 2011;3():1500-10.
2010: Florence Schaffner; Henri H Versteeg; Anja Schillert; Naho Yokota; Lars C Petersen; Barbara M Mueller; Wolfram Ruf
Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.
Blood 2010;116(26):6106-13.
2010: Wolfram Ruf; Henri H Versteeg
Tissue factor mutated at the allosteric Cys186-Cys209 disulfide bond is severely impaired in decrypted procoagulant activity.
Blood 2010;116(3):500-1; author reply 502-3.
2008: Lois W Brüggemann; Henri H Versteeg; Tatjana M Niers; Pieter H Reitsma; C Arnold Spek
Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders.
Journal of cellular and molecular medicine 2008;12(6B):2622-7.
2008: Sander H Diks; Maria A Sartori da Silva; Jan-Luuk Hillebrands; Robert J Bink; Henri H Versteeg; Carina van Rooijen; Anke Brouwers; Ajay B Chitnis; Maikel P Peppelenbosch; Danica Zivkovic
d-Asb11 is an essential mediator of canonical Delta-Notch signalling.
Nature cell biology 2008;10(10):1190-8.
2008: Henri H Versteeg; Florence Schaffner; Marjolein Kerver; Lesley G Ellies; Patricia Andrade-Gordon; Barbara M Mueller; Wolfram Ruf
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.
Cancer research 2008;68(17):7219-27.
2008: Lois W Brüggemann; Henri H Versteeg; Pieter H Reitsma; C Arnold Spek
High factor VIIa levels do not promote tumor metastasis.
Thrombosis and haemostasis 2008;99(4):787-8.
2008: Henri H Versteeg; Florence Schaffner; Marjolein Kerver; Helle H Petersen; Jasimuddin Ahamed; Brunhilde Felding-Habermann; Yoshikazu Takada; Barbara M Mueller; Wolfram Ruf
Inhibition of tissue factor signaling suppresses tumor growth.
Blood 2008;111(1):190-9.
2007: Henri H Versteeg; Wolfram Ruf
Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity.
The Journal of biological chemistry 2007;282(35):25416-24.
2007: Keren S Borensztajn; Maarten F Bijlsma; Angelique P Groot; Lois W Brüggemann; Henri H Versteeg; Pieter H Reitsma; Maikel Peppelenbosch; C Arnold Spek
Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation.
Experimental cell research 2007;313(12):2622-33.
2007: Clara P W Klerk; Renée M Overmeer; T M H Niers; Henri H Versteeg; Dick J Richel; Tessa Buckle; Cornelis J F Van Noorden; Olaf van Tellingen
Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals.
BioTechniques 2007;43(1 Suppl):7-13, 30.
2006: Vivien M Chen; Jasimuddin Ahamed; Henri H Versteeg; Michael C Berndt; Wolfram Ruf; Philip J Hogg
Evidence for activation of tissue factor by an allosteric disulfide bond.
Biochemistry 2006;45(39):12020-8.
2006: Jasimuddin Ahamed; Henri H Versteeg; Marjolein Kerver; Vivien M Chen; Barbara M Mueller; Philip J Hogg; Wolfram Ruf
Disulfide isomerization switches tissue factor from coagulation to cell signaling.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):13932-7.
2006: Henri H Versteeg; Wolfram Ruf
Emerging insights in tissue factor-dependent signaling events.
Seminars in thrombosis and hemostasis 2006;32(1):24-32.
2006: Alexandre D Martins Cavagis; Carmen Veríssima Ferreira; Henri H Versteeg; Cristiane Fernandes Assis; Carina L Bos; Sylvia A Bleuming; Sander H Diks; Hiroshi Aoyama; Maikel Peppelenbosch
Tetrahydroxyquinone induces apoptosis of leukemia cells through diminished survival signaling.
Experimental hematology 2006;34(2):188-96.
2004: Sylvia Knapp; Sébastien Gibot; Alex de Vos; Henri H Versteeg; Marco COLONna; Tom van der Poll
Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7131-4.
2004: Saskia H H F Schoenmakers; Henri H Versteeg; Angelique P Groot; Pieter H Reitsma; C Arnold Spek
Tissue factor haploinsufficiency during endotoxin induced coagulation and inflammation in mice.
Journal of thrombosis and haemostasis : JTH 2004;2(12):2185-93.
2004: Carmen Veríssima Ferreira; Carina L Bos; Henri H Versteeg; Giselle Z Justo; Nelson Durán; Maikel Peppelenbosch
Molecular mechanism of violacein-mediated human leukemia cell death.
Blood 2004;104(5):1459-64.
2004: Carina L Bos; Dick J Richel; Tita Ritsema; Maikel Peppelenbosch; Henri H Versteeg
Prostanoids and prostanoid receptors in signal transduction.
The international journal of biochemistry & cell biology 2004;36(7):1187-205.
2004: Henri H Versteeg; C Arnold Spek; Sjoukje H Slofstra; Sander H Diks; Dick J Richel; Maikel Peppelenbosch
FVIIa:TF induces cell survival via G12/G13-dependent Jak/STAT activation and BclXL production.
Circulation research 2004;94(8):1032-40.
2004: Henri H Versteeg; Dick J Richel; Maikel Peppelenbosch; C Arnold Spek
Concerted action of coagulation factors on cell survival.
Journal of thrombosis and haemostasis : JTH 2004;2(4):673-4.
2004: Henri H Versteeg; C Arnold Spek; Dick J Richel; Maikel Peppelenbosch
Coagulation factors VIIa and Xa inhibit apoptosis and anoikis.
Oncogene 2004;23(2):410-7.
2004: Henri H Versteeg; C Arnold Spek; Maikel Peppelenbosch; Dick J Richel
Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathways.
Molecular medicine (Cambridge, Mass.) 2004;10(1-6):6-11.
2004: Henri H Versteeg
Tissue factor as an evolutionary conserved cytokine receptor: Implications for inflammation and signal transduction.
Seminars in hematology 2004;41(1 Suppl 1):168-72.
2003: Sander H Diks; James C H Hardwick; Remco M Diab; Marije M van Santen; Henri H Versteeg; Sander J H van Deventer; Dick J Richel; Maikel Peppelenbosch
Activation of the canonical beta-catenin pathway by histamine.
The Journal of biological chemistry 2003;278(52):52491-6.
2003: Henri H Versteeg; Maikel Peppelenbosch; C Arnold Spek
Tissue factor signal transduction in angiogenesis.
Carcinogenesis 2003;24(6):1009-13.
2003: Jan M H Van Den Brande; Henri Braat; Gijs R van den Brink; Henri H Versteeg; Christiaan A Bauer; Inge Hoedemaeker; Catherine van Montfrans; Daan W Hommes; Maikel Peppelenbosch; Sander J H van Deventer
Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease.
Gastroenterology 2003;124(7):1774-85.
2003: Henri H Versteeg; H L Bresser; C Arnold Spek; Dick J Richel; Sander J H van Deventer; Maikel Peppelenbosch
Regulation of the p21Ras-MAP kinase pathway by factor VIIa.
Journal of thrombosis and haemostasis : JTH 2003;1(5):1012-8.
2003: Maikel Peppelenbosch; Henri H Versteeg; C Arnold Spek
In silico tissue factor analysis: a bit-to-bit comparison.
Thrombosis and haemostasis 2003;89(3):592-3.
2002: Henri H Versteeg; Brit Sorensen; Sjoukje H Slofstra; Jan H M Van den Brande; Jord Stam; Paul M P van Bergen en Henegouwen; Dick J Richel; Lars C Petersen; Maikel Peppelenbosch
VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation.
The Journal of biological chemistry 2002;277(30):27065-72.
2002: Bernt van den Blink; A J van der Kleij; Henri H Versteeg; Maikel Peppelenbosch
Immunomodulatory effect of oxygen and pressure.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2002;132(1):193-7.
2001: Henri H Versteeg; Maikel Peppelenbosch; C Arnold Spek
The pleiotropic effects of tissue factor: a possible role for factor VIIa-induced intracellular signalling?
Thrombosis and haemostasis 2001;86(6):1353-9.
2001: Maikel Peppelenbosch; Henri H Versteeg
Cell biology of tissue factor, an unusual member of the cytokine receptor family.
Trends in cardiovascular medicine 2001;11(8):335-9.
2001: Jord Stam; Willie J.C. Geerts; Henri H Versteeg; Arie J Verkleij; Paul M P van Bergen en Henegouwen
The v-Crk oncogene enhances cell survival and induces activation of protein kinase B/Akt.
The Journal of biological chemistry 2001;276(27):25176-83.
2000: Henri H Versteeg; Evert H J Nijhuis; Gijs R van den Brink; M Evertzen; Gwenda Pynaert; Sander J H van Deventer; Paul J Coffer; Maikel Peppelenbosch
A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein.
The Biochemical journal 2000;350 Pt 3():717-22.
2000: Henri H Versteeg; I Hoedemaeker; Sander H Diks; Jord Stam; M Spaargaren; Paul M P van Bergen en Henegouwen; Sander J H van Deventer; Maikel Peppelenbosch
Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac.
The Journal of biological chemistry 2000;275(37):28750-6.
2000: Gijs R van den Brink; T O'Toole; James C H Hardwick; Daniëlle E M van den Boogaardt; Henri H Versteeg; Sander J H van Deventer; Maikel Peppelenbosch
Leptin signaling in human peripheral blood mononuclear cells, activation of p38 and p42/44 mitogen-activated protein (MAP) kinase and p70 S6 kinase.
Molecular cell biology research communications : MCBRC 2000;4(3):144-50.
2000: Henri H Versteeg; M W Evertzen; Sander J H van Deventer; Maikel Peppelenbosch
The role of phosphatidylinositide-3-kinase in basal mitogen-activated protein kinase activity and cell survival.
FEBS letters 2000;465(1):69-73.
1999: Henri H Versteeg; Paul M P van Bergen en Henegouwen; Sander J H van Deventer; Maikel Peppelenbosch
Cyclooxygenase-dependent signalling: molecular events and consequences.
FEBS letters 1999;445(1):1-5.
1998: B Whitehead; Marco Tessari; Henri H Versteeg; S van Delft; Paul M P van Bergen en Henegouwen; Geerten W Vuister
Sequence-specific 1H, 13C and 15N assignment of the EH1 domain of mouse Eps15.
Journal of biomolecular NMR 1998;12(3):465-6.