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Rogier Versteeg

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TOP 3
Jens Bunt; Nancy A Hasselt; Jan Koster; Rogier Versteeg; Danny A Zwijnenburg; Marcel Kool
OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels.
Johannes H Schulte; S Schulte; F Speleman; T Thor; J Vandesompele; Rogier Versteeg; A Bohrer; Katleen De Preter; Angelika Eggert; Lukas Heukamp; A Künkele; S Lefever; S Lindner; J Maurer; J Molenaar; H Schorle; Alexander Schramm
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells.
Linda J Valentijn; Johan van Nes; Peter G van Sluis; Rachida Ait Aissa; Marloes E C Broekmans; Franciska Haneveld; Jan Koster; Jan J Molenaar; Rogier Versteeg
Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification.

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2013: Jens Bunt; Nancy A Hasselt; Jan Koster; Rogier Versteeg; Danny A Zwijnenburg; Marcel Kool
OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels.
Acta neuropathologica 2013;125(3):385-94.
2013: Johannes H Schulte; S Schulte; F Speleman; T Thor; J Vandesompele; Rogier Versteeg; A Bohrer; Katleen De Preter; Angelika Eggert; Lukas Heukamp; A Künkele; S Lefever; S Lindner; J Maurer; J Molenaar; H Schorle; Alexander Schramm
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells.
Oncogene 2013;32(8):1059-65.
2012: Linda J Valentijn; Johan van Nes; Peter G van Sluis; Rachida Ait Aissa; Marloes E C Broekmans; Franciska Haneveld; Jan Koster; Jan J Molenaar; Rogier Versteeg
Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(47):19190-5.
2012: Jan J Molenaar; Alexander Schramm; Isabella Bray; Marloes Broekmans; Huib N Caron; Raquel Domingo-Fernández; Ksenija Drabek; Marli E Ebus; Angelika Eggert; Matthias Fischer; Franciska Haneveld; Lukas Heukamp; Kristina Kieckbusch; Ludger Klein-Hitpass; Jan Koster; Sven Lindner; Pieter Mestdagh; Frank Speleman; Annika Sprüssel; Raymond L Stallings; Theresa Thor; Linda J Valentijn; Johan van Nes; Max M van Noesel; Peter G van Sluis; Jo Vandesompele; Luigi Varesio; Rogier Versteeg; Richard Volckmann; Johannes H Schulte
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.
Nature genetics 2012;44(11):1199-206.
2012: Darya Yu Orlova; Lenka Stixová; Roman Stoklasa; Rogier Versteeg; Gabriela Šustáčková; Andrei V Chernyshev; Hinco J Gierman; Stanislav Kozubek; Soňa Legartová; Pavel Matula; Ruslan N Medvedev; Eva Bártová
Arrangement of nuclear structures is not transmitted through mitosis but is identical in sister cells.
Journal of cellular biochemistry 2012;113(11):3313-29.
2012: Fieke Lamers; Huib N Caron; Ilona J M den Hartog; Marli E Ebus; Jan Koster; Ingrid Øra; Linda Schild; Rogier Versteeg; Ellen M Westerhout; Jan J Molenaar
Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth.
European journal of cancer (Oxford, England : 1990) 2012;48(16):3093-103.
2012: Jens Bunt; Mohamed Hamdi; Nancy E Hasselt; Jan Koster; Rogier Versteeg; Danny A Zwijnenburg; Marcel Kool
OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells.
International journal of cancer. Journal international du cancer 2012;131(2):E21-32.
2012: Kristel Kemper; Jan Koster; Louis Vermeulen; Miranda Versloot; Rogier Versteeg; Joanne Bleackley; Katherine Cameron; Selçuk Colak; Joan H de Jong; Felipe de Sousa e Melo; Jan Paul Medema
Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(11):3132-41.
2012: Annelies Fieuw; Candy Kumps; Björn Menten; Rosa Noguera; Filip Pattyn; Alexander Schramm; Johannes H Schulte; Francesca Antonacci; Patrick Buckley; Anne De Paepe; Katleen De Preter; Angelika Eggert; Raymond L Stallings; Peter Sudmant; Nadine Van Roy; Jo Vandesompele; Sarah Vergult; Rogier Versteeg; Frank Speleman
Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas.
International journal of cancer. Journal international du cancer 2012;130(11):2599-606.
2012: Jan J Molenaar; Piet Molenaar; Ingrid Øra; Evan E Santo; Linda Schild; Peter Stroeken; Linda J Valentijn; Jennemiek van Arkel; Ida van der Ploeg; Johan van Nes; Max M van Noesel; Peter G van Sluis; Huib N Caron; Marli E Ebus; Mohamed Hamdi; Franciska Haneveld; Jan Koster; Arjan Lakeman; Ellen M Westerhout; Bart A Westerman; Danny A Zwijnenburg; Rogier Versteeg
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes.
Nature 2012;483(7391):589-93.
2012: E E Santo; Johannes H Schulte; R L Stallings; Peter G van Sluis; Jo Vandesompele; J Vermeulen; Rogier Versteeg; Ingrid Øra; Patrick Buckley; Huib N Caron; M E Ebus; Angelika Eggert; D Gisselsson; J Koster; A Lakeman; S Lindner; J J Molenaar
Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma.
Oncogene 2012;31(12):1571-81.
2012: Janine Stutterheim; Johannes Bras; Huib N Caron; Emmy den Ouden; Ingrid Øra; C. Ellen van der Schoot; Peter G van Sluis; Rogier Versteeg; Lily Zappeij-Kannegieter; Godelieve A M Tytgat
Stability of PCR targets for monitoring minimal residual disease in neuroblastoma.
The Journal of molecular diagnostics : JMD 2012;14(2):168-75.
2012: Fieke Lamers; Huib N Caron; Jan Koster; Linda Schild; Rogier Versteeg; Jan J Molenaar
Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression.
European journal of cancer (Oxford, England : 1990) 2012;48(5):763-71.
2012: Janine Stutterheim; Godelieve A M Tytgat; Huib N Caron; Emmy den Ouden; Fatima Ait Ichou; Rogier Versteeg; C. Ellen van der Schoot
Methylated RASSF1a is the first specific DNA marker for minimal residual disease testing in neuroblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(3):808-14.
2012: Fieke Lamers; Huib N Caron; Jan Koster; Linda Schild; Frank Speleman; Peter G van Sluis; Rogier Versteeg; Ellen M Westerhout; Ingrid Øra; Jan J Molenaar
Identification of BIRC6 as a novel intervention target for neuroblastoma therapy.
BMC cancer 2012;12():285.
2012: Jan J Molenaar; Ingrid Øra; Frank Speleman; Peter G van Sluis; Huib N Caron; Katleen De Preter; Marli E Ebus; David Gisselsson; Jan Koster; Ellen M Westerhout; Rogier Versteeg
Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis.
Genes, chromosomes & cancer 2012;51(1):10-9.
2011: Katleen De Preter; Elzbieta Drozynska; Angelika Eggert; Michael D Hogarty; Ewa Izycka-Swieszewska; Geneviève Laureys; Wendy B London; Pieter Mestdagh; Jan J Molenaar; Arlene Naranjo; Rosa Noguera; Marta Piqueras; Benjamin Schowe; Alexander Schramm; Johannes H Schulte; Frank Speleman; Raymond L Stallings; Nadine Van Roy; Peter van Sluis; Isabella Bray; Kenneth Bryan; Victoria Castel; Caifu Chen; Joëlle Vermeulen; Rogier Versteeg; Fjoralba Zeka; Jo Vandesompele
miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(24):7684-92.
2011: Felipe de Sousa E Melo; Evelien Dekker; Evelyn Fessler; Jan Koster; Joyce Buikhuisen; Kate Cameron; Selcuk Colak; Joan H de Jong; Steven T Pals; Pramudita R Prasetyanti; Dick J Richel; Hans Rodermond; Jurriaan B Tuynman; Marc J van de Vijver; Saskia P van den Bergh; Chris M van der Loos; Louis Vermeulen; Rogier Versteeg; Jan Paul Medema
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients.
Cell stem cell 2011;9(5):476-85.
2011: Fieke Lamers; Linda Schild; Ida van der Ploeg; Rogier Versteeg; Huib N Caron; Marli E Ebus; Bo R Hansen; Troels Koch; Jan Koster; Jan J Molenaar
Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe.
Endocrine-related cancer 2011;18(6):657-68.
2011: Kathrin Teller; Stefanie Thamm; Rogier Versteeg; Corella S Casas-Delucchi; Thomas Cremer; Doris Illner; Mireille Indemans; Marion Cremer
A top-down analysis of Xa- and Xi-territories reveals differences of higher order structure at ≥ 20 Mb genomic length scales.
Nucleus (Austin, Tex.) 2011;2(5):465-77.
2011: J Stutterheim; L Zappeij-Kannegieter; Rogier Versteeg; Huib N Caron; C E van der Schoot; G A M Tytgat
The prognostic value of fast molecular response of marrow disease in patients aged over 1 year with stage 4 neuroblastoma.
European journal of cancer (Oxford, England : 1990) 2011;47(8):1193-202.
2011: Jens Bunt; Nancy E Hasselt; Jan Koster; Rogier Versteeg; Danny A Zwijnenburg; Marcel Kool
Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma.
PloS one 2011;6(10):e26058.
2010: Jens Bunt; Talitha G de Haas; Nancy E Hasselt; Danny A Zwijnenburg; Jan Koster; Rogier Versteeg; Marcel Kool
Regulation of cell cycle genes and induction of senescence by overexpression of OTX2 in medulloblastoma cell lines.
Molecular cancer research : MCR 2010;8(10):1344-57.
2010: J J Molenaar; M E Ebus; J Koster; E Santo; Dirk Geerts; Rogier Versteeg; Huib N Caron
Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells.
Oncogene 2010;29(18):2739-45.
2010: Dirk Geerts; Jan Koster; David Albert; Dana-Lynn Takeko Koomoa; David J Feith; Anthony E Pegg; Richard Volckmann; Huib N Caron; Rogier Versteeg; André S Bachmann
The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification.
International journal of cancer. Journal international du cancer 2010;126(9):2012-24.
2010: Ingrid Revet; Gerda Huizenga; Jan Koster; Richard Volckmann; Peter G van Sluis; Rogier Versteeg; Dirk Geerts
MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3.
Cancer letters 2010;289(2):195-207.
2010: Gerben Schaaf; Mohamed Hamdi; Danny Zwijnenburg; Arjan Lakeman; Dirk Geerts; Rogier Versteeg; Marcel Kool
Silencing of SPRY1 triggers complete regression of rhabdomyosarcoma tumors carrying a mutated RAS gene.
Cancer research 2010;70(2):762-71.
2009: Klaartje van Engelen; Johannes H M Merks; Jan Lam; leontien c kremer; Manouk Backes; Marieke J H Baars; H J H van der Pal; Alex V Postma; Rogier Versteeg; Huib N Caron; Barbara J M Mulder
Prevalence of congenital heart defects in neuroblastoma patients: a cohort study and systematic review of literature.
European journal of pediatrics 2009;168(9):1081-90.
2009: Jan J Molenaar; Marli E Ebus; Dirk Geerts; Jan Koster; Fieke Lamers; Linda J Valentijn; Ellen M Westerhout; Rogier Versteeg; Huib N Caron
Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12968-73.
2009: Janine Stutterheim; Annemieke Gerritsen; Lily Zappeij-Kannegieter; Bilgehan Yalcin; Rob Dee; Max M van Noesel; Frank Berthold; Rogier Versteeg; Huib N Caron; C Ellen van der Schoot; Godelieve A M Tytgat
Detecting minimal residual disease in neuroblastoma: the superiority of a panel of real-time quantitative PCR markers.
Clinical chemistry 2009;55(7):1316-26.
2009: Johannes H Schulte; Falk Pentek; Wolfgang Hartmann; Alexander Schramm; Nicolaus Friedrichs; Ingrid Øra; Jan Koster; Rogier Versteeg; Jutta Kirfel; Reinhard Buettner; Angelika Eggert
The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo.
International journal of cancer. Journal international du cancer 2009;124(10):2488-94.
2009: Sander R van Hooff; Jan Koster; Tim Hulsen; Barbera van Schaik; Marco Roos; Marcel F van Batenburg; Rogier Versteeg; Antoine H C van Kampen
The construction of genome-based transcriptional units.
Omics : a journal of integrative biology 2009;13(2):105-14.
2009: Johannes H Schulte; Soyoung Lim; Alexander Schramm; Nicolaus Friedrichs; Jan Koster; Rogier Versteeg; Ingrid Øra; Kristian Pajtler; Ludger Klein-Hitpass; Steffi Kuhfittig-Kulle; Eric Metzger; Roland Schüle; Angelika Eggert; Reinhard Buettner; Jutta Kirfel
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy.
Cancer research 2009;69(5):2065-71.
2008: Talitha de Haas; Nancy Hasselt; Dirk Troost; Huib N Caron; Mara Popovic; Lorna Zadravec Zaletel; Wieslawa Grajkowska; Marta Perek; Maria-Chiara Osterheld; David Ellison; Frank Baas; Rogier Versteeg; Marcel Kool
Molecular risk stratification of medulloblastoma patients based on immunohistochemical analysis of MYC, LDHB, and CCNB1 expression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(13):4154-60.
2008: Jan J Molenaar; Marli E Ebus; Jan Koster; Peter G van Sluis; Carel J M van Noesel; Rogier Versteeg; Huib N Caron
Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma.
Cancer research 2008;68(8):2599-609.
2008: Arjen Koppen; Rachida Ait-Aissa; Jan Koster; Ingrid Øra; Johannes Bras; Peter G van Sluis; Huib N Caron; Rogier Versteeg; Linda J Valentijn
Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN.
International journal of cancer. Journal international du cancer 2008;122(7):1455-64.
2008: Ingrid Revet; Gerda Huizenga; Alvin Chan; Jan Koster; Richard Volckmann; Peter G van Sluis; Ingrid Øra; Rogier Versteeg; Dirk Geerts
The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma.
Experimental cell research 2008;314(4):707-19.
2008: Marcel Kool; Jan Koster; Jens Bunt; Nancy E Hasselt; Arjan Lakeman; Peter G van Sluis; Dirk Troost; Netteke Schouten-van Meeteren; Huib N Caron; Jacqueline Cloos; Alan Mrsić; Bauke Ylstra; Wieslawa Grajkowska; Wolfgang Hartmann; Torsten Pietsch; David Ellison; Steven C Clifford; Rogier Versteeg
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.
PloS one 2008;3(8):e3088.
2007: Evi Michels; Jo Vandesompele; Katleen De Preter; Jasmien Hoebeeck; Joëlle Vermeulen; Alexander Schramm; Jan J Molenaar; Björn Menten; Barbara Marques; Raymond L Stallings; Valérie Combaret; Christine Devalck; Anne De Paepe; Rogier Versteeg; Angelika Eggert; Geneviève Laureys; Nadine Van Roy; Frank Speleman
ArrayCGH-based classification of neuroblastoma into genomic subgroups.
Genes, chromosomes & cancer 2007;46(12):1098-108.
2007: Dirk Geerts; Christopher J Wallick; Dana-Lynn Takeko Koomoa; Jan Koster; Rogier Versteeg; Ramon Christopher V Go; André S Bachmann
Expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in neuroblastoma: correlation with clinical features, cellular localization, and cerulenin-mediated apoptosis regulation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(21):6312-9.
2007: Arjen Koppen; Rachida Ait-Aissa; Jan Koster; Peter G van Sluis; Ingrid Øra; Huib N Caron; Richard Volckmann; Rogier Versteeg; Linda J Valentijn
Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.
European journal of cancer (Oxford, England : 1990) 2007;43(16):2413-22.
2007: Arjen Koppen; Rachida Ait-Aissa; Saskia Hopman; Jan Koster; Franciska Haneveld; Rogier Versteeg; Linda J Valentijn
Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation.
Cancer letters 2007;256(2):218-28.
2007: Hinco J Gierman; Mireille H G Indemans; Jan Koster; Sandra Goetze; Jurgen Seppen; Dirk Geerts; Roel Van Driel; Rogier Versteeg
Domain-wide regulation of gene expression in the human genome.
Genome research 2007;17(9):1286-95.
2007: Sandra Goetze; Julio Mateos-Langerak; Hinco J Gierman; Wim de Leeuw; Osdilly Giromus; Mireille H G Indemans; Jan Koster; Vladan Ondrej; Rogier Versteeg; Roel Van Driel
The three-dimensional structure of human interphase chromosomes is related to the transcriptome map.
Molecular and cellular biology 2007;27(12):4475-87.
2007: Roman Zinner; Kathrin Teller; Rogier Versteeg; Thomas Cremer; Marion Cremer
Biochemistry meets nuclear architecture: multicolor immuno-FISH for co-localization analysis of chromosome segments and differentially expressed gene loci with various histone methylations.
Advances in enzyme regulation 2007;47():223-41.
2007: Jørn R Henriksen; Cecilie Løkke; Martin Hammerø; Dirk Geerts; Rogier Versteeg; Trond Flaegstad; Christer Einvik
Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines.
Nucleic acids research 2007;35(9):e67.
2006: Monique H A Kester; George G J M Kuiper; Rogier Versteeg; Theo J Visser
Regulation of type III iodothyronine deiodinase expression in human cell lines.
Endocrinology 2006;147(12):5845-54.
2006: Linda J Valentijn; Jan Koster; Rogier Versteeg
Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV.
Genomics 2006;87(4):483-9.
2006: Talitha de Haas; Esmeralda Oussoren; Wieslawa Grajkowska; Marta Perek-Polnik; Mara Popovic; Lorna Zadravec Zaletel; Marzia Perera; Giorgio Corte; Oliver Wirths; Peter G van Sluis; Torsten Pietsch; Dirk Troost; Frank Baas; Rogier Versteeg; Marcel Kool
OTX1 and OTX2 expression correlates with the clinicopathologic classification of medulloblastomas.
Journal of neuropathology and experimental neurology 2006;65(2):176-86.
2005: Vera Limpt, van; Alvin Chan; Alexander Schramm; Angelika Eggert; Rogier Versteeg
Phox2B mutations and the Delta-Notch pathway in neuroblastoma.
Cancer letters 2005;228(1-2):59-63.
2005: Alexander Schramm; Johannes H Schulte; Kathy Astrahantseff; Ognjan Apostolov; Vera van Limpt; Hauke Sieverts; Steffi Kuhfittig-Kulle; Petra Pfeiffer; Rogier Versteeg; Angelika Eggert
Biological effects of TrkA and TrkB receptor signaling in neuroblastoma.
Cancer letters 2005;228(1-2):143-53.
2005: Dirk Geerts; Ingrid Revet; Gerda Jorritsma; Nathalie Schilderink; Rogier Versteeg
MEIS homeobox genes in neuroblastoma.
Cancer letters 2005;228(1-2):43-50.
2005: Linda J Valentijn; Arjen Koppen; Ronald van Asperen; Heather A Root; Franciska Haneveld; Rogier Versteeg
Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, Cdc42, and nm23 genes.
Cancer research 2005;65(8):3136-45.
2004: Vera Limpt, van; Alexander Schramm; Arjan van Lakeman; Peter Sluis; Alvin Chan; Max M van Noesel; Frank Baas; Huib N Caron; Angelika Eggert; Rogier Versteeg
The Phox2B homeobox gene is mutated in sporadic neuroblastomas.
Oncogene 2004;23(57):9280-8.
2004: Max M van Noesel; Rogier Versteeg
Pediatric neuroblastomas: genetic and epigenetic 'danse macabre'.
Gene 2004;325():1-15.
2003: Max M van Noesel; Saskia van Bezouw; Paul A Voûte; James G Herman; Rob Pieters; Rogier Versteeg
Clustering of hypermethylated genes in neuroblastoma.
Genes, chromosomes & cancer 2003;38(3):226-33.
2003: Rogier Versteeg; Barbera van Schaik; Marinus F van Batenburg; Marco Roos; Ramin Monajemi; Huib N Caron; Harmen J Bussemaker; Antoine H C van Kampen
The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes.
Genome research 2003;13(9):1998-2004.
2003: Max M van Noesel; Rob Pieters; Paul A Voûte; Rogier Versteeg
The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis.
Cancer letters 2003;197(1-2):165-72.
2003: Dirk Geerts; Nathalie Schilderink; Gerda Jorritsma; Rogier Versteeg
The role of the MEIS homeobox genes in neuroblastoma.
Cancer letters 2003;197(1-2):87-92.
2003: Vera Limpt, van; Alvin J Chan; Peter G van Sluis; Huib N Caron; Carel J M van Noesel; Rogier Versteeg
High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type.
International journal of cancer. Journal international du cancer 2003;105(1):61-9.
2003: Jan J Molenaar; Peter G van Sluis; Kathy Boon; Rogier Versteeg; Huib N Caron
Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma.
Genes, chromosomes & cancer 2003;36(3):242-9.
2002: Nadine Van Roy; Jo Vandesompele; Geert Berx; Katrien Staes; Mireille Van Gele; Els De Smet; Anne De Paepe; Geneviève Laureys; Pauline van der Drift; Rogier Versteeg; Frans van Roy; Frank Speleman
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients.
Genes, chromosomes & cancer 2002;35(2):113-20.
2002: Marc B Godfried; Monique Veenstra; A Valent; Peter Sluis; Paul A Voûte; Rogier Versteeg; Huib N Caron
Lack of interstitial chromosome 1p deletions in clinically-detected neuroblastoma.
European journal of cancer (Oxford, England : 1990) 2002;38(11):1513-9.
2002: Max M van Noesel; Saskia van Bezouw; Gajja S Salomons; Paul A Voûte; Rob Pieters; Stephen B Baylin; James G Herman; Rogier Versteeg
Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation.
Cancer research 2002;62(7):2157-61.
2002: Marc B Godfried; Monique Veenstra; Peter v Sluis; Kathy Boon; Ronald v Asperen; Marie Christien Hermus; Barbara D C v Schaik; Tom P A Voûte; Manfred Schwab; Rogier Versteeg; Huib N Caron
The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2.
Oncogene 2002;21(13):2097-101.
2001: N Spieker; M Beitsma; Peter G van Sluis; A Chan; Huib N Caron; Rogier Versteeg
Three chromosomal rearrangements in neuroblastoma cluster within a 300-kb region on 1p36.1.
Genes, chromosomes & cancer 2001;31(2):172-81.
2001: Kathy Boon; Huib N Caron; Ronald van Asperen; Linda J Valentijn; Marie Christien Hermus; Peter G van Sluis; I Roobeek; I Weis; Paul A Voûte; M Schwab; Rogier Versteeg
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis.
The EMBO journal 2001;20(6):1383-93.
2001: Huib N Caron; Barbera van Schaik; M van der Mee ; Frank Baas; Gregory J Riggins; Peter G van Sluis; Marie Christien Hermus; Ronald van Asperen; Kathy Boon; Paul A Voûte; Siem H Heisterkamp; Antoine H C van Kampen; Rogier Versteeg
The human transcriptome map: clustering of highly expressed genes in chromosomal domains.
Science (New York, N.Y.) 2001;291(5507):1289-92.
2001: Huib N Caron; N Spieker; Marc B Godfried; Monique Veenstra; Peter G van Sluis; J de Kraker; Paul A Voûte; Rogier Versteeg
Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted.
Genes, chromosomes & cancer 2001;30(2):168-74.
2001: N Spieker; Peter G van Sluis; M Beitsma; Kathy Boon; Barbera van Schaik; Antoine H C van Kampen; Huib N Caron; Rogier Versteeg
The MEIS1 oncogene is highly expressed in neuroblastoma and amplified in cell line IMR32.
Genomics 2001;71(2):214-21.
2000: Vera Limpt, van; Alvin Chan; Huib N Caron; Peter Sluis; Kathy Boon; Marie Christien Hermus; Rogier Versteeg
SAGE analysis of neuroblastoma reveals a high expression of the human homologue of the Drosophila Delta gene.
Medical and pediatric oncology 2000;35(6):554-8.
2000: Antoine H C van Kampen; Barbera van Schaik; Erwin Pauws; Erna M C Michiels; Jan M Ruijter; Huib N Caron; Rogier Versteeg; Siem H Heisterkamp; Jack Leunissen; Frank Baas; M van der Mee
USAGE: a web-based approach towards the analysis of SAGE data. Serial Analysis of Gene Expression.
Bioinformatics (Oxford, England) 2000;16(10):899-905.
2000: N Spieker; M Beitsma; Peter G van Sluis; I Roobeek; Johan T den Dunnen; Frank Speleman; Huib N Caron; Rogier Versteeg
An integrated 5-Mb physical, genetic, and radiation hybrid map of a 1p36.1 region implicated in neuroblastoma pathogenesis.
Genes, chromosomes & cancer 2000;27(2):143-52.
1999: Pauline van der Drift; A Chan; G Zehetner; Andries Westerveld; Rogier Versteeg
Multiple MSP pseudogenes in a local repeat cluster on 1p36.2: An expanding genomic graveyard?
Genomics 1999;62(1):74-81.
1999: Wim Wuyts; N Spieker; Nadine Van Roy; K De Boulle; A De Paepe; Patrick J Willems; Wim Van Hul; Rogier Versteeg; Frank Speleman
Refined physical mapping and genomic structure of the EXTL1 gene.
Cytogenetics and cell genetics 1999;86(3-4):267-70.
1998: Mireille Van Gele; Nadine Van Roy; Salve G Ronan; Ludwine MESSIAEN; Jo Vandesompele; M L Geerts; J M Naeyaert; E Blennow; I Bar-Am; Tapas K Das Gupta; Pauline van der Drift; Rogier Versteeg; J Helen Leonard; Frank Speleman
Molecular analysis of 1p36 breakpoints in two Merkel cell carcinomas.
Genes, chromosomes & cancer 1998;23(1):67-71.
1997: Mireille Van Gele; Nadine Van Roy; A Jauch; Geneviève Laureys; Yves Benoit; Vera R J Schelfhout; Christian R De Potter; P Brock; Anne Uyttebroeck; Raf Sciot; E Schuuring; Rogier Versteeg; Frank Speleman
Sensitive and reliable detection of genomic imbalances in human neuroblastomas using comparative genomic hybridisation analysis.
European journal of cancer (Oxford, England : 1990) 1997;33(12):1979-82.
1997: Nadine Van Roy; Geneviève Laureys; Mireille Van Gele; G Opdenakker; R Miura; Pauline van der Drift; A Chan; Rogier Versteeg; Frank Speleman
Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes.
European journal of cancer (Oxford, England : 1990) 1997;33(12):1974-8.
1997: Nadine Van Roy; A Jauch; Mireille Van Gele; Geneviève Laureys; Rogier Versteeg; Anne De Paepe; Thomas Cremer; Frank Speleman
Comparative genomic hybridization analysis of human neuroblastomas: detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines.
Cancer genetics and cytogenetics 1997;97(2):135-42.
1996: N C Cheng; M Beitsma; A Chan; I Op den Camp; Andries Westerveld; J Pronk; Rogier Versteeg
Lack of class I HLA expression in neuroblastoma is associated with high N-myc expression and hypomethylation due to loss of the MEMO-1 locus.
Oncogene 1996;13(8):1737-44.
1996: H Caron; P van Sluis; R Buschman; R Pereira do Tanque; P Maes; L Beks; Jan de Kraker; Paul A Voûte; Gilles Vergnaud; Andries Westerveld; Rosalyn Slater; Rogier Versteeg
Allelic loss of the short arm of chromosome 4 in neuroblastoma suggests a novel tumour suppressor gene locus.
Human genetics 1996;97(6):834-7.
1996: N C Cheng; A J Chan; M M Beitsma; Frank Speleman; Andries Westerveld; Rogier Versteeg
A human modifier of methylation for class I HLA genes (MEMO-1) maps to chromosomal bands 1p35-36.1.
Human molecular genetics 1996;5(3):309-17.
1996: Robert M W Hofstra; N C Cheng; C Hansen; Rein P Stulp; T Stelwagen; N Clausen; Niels Tommerup; H Caron; Andries Westerveld; Rogier Versteeg; Charles H C M Buys
No mutations found by RET mutation scanning in sporadic and hereditary neuroblastoma.
Human genetics 1996;97(3):362-4.
1996: H Caron; P van Sluis; Jan de Kraker; Jos P M Bökkerink; M Egeler; Geneviève Laureys; Rosalyn Slater; Andries Westerveld; Paul A Voûte; Rogier Versteeg
Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma.
The New England journal of medicine 1996;334(4):225-30.
1995: Pauline van der Drift; A Chan; Geneviève Laureys; Nadine Van Roy; G Sickmann; J den Dunnen; Andries Westerveld; Frank Speleman; Rogier Versteeg
Balanced translocation in a neuroblastoma patient disrupts a cluster of small nuclear RNA U1 and tRNA genes in chromosomal band 1p36.
Genes, chromosomes & cancer 1995;14(1):35-42.
1995: Nadine Van Roy; Anne Forus; Ola Myklebost; N C Cheng; Rogier Versteeg; Frank Speleman
Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP.
Cancer genetics and cytogenetics 1995;82(2):151-4.
1995: Geneviève Laureys; Frank Speleman; Rogier Versteeg; Pauline van der Drift; A Chan; J Leroy; U Francke; G Opdenakker; Nadine Van Roy
Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.
Oncogene 1995;10(6):1087-93.
1995: N C Cheng; Nadine Van Roy; A Chan; M Beitsma; Andries Westerveld; Frank Speleman; Rogier Versteeg
Deletion mapping in neuroblastoma cell lines suggests two distinct tumor suppressor genes in the 1p35-36 region, only one of which is associated with N-myc amplification.
Oncogene 1995;10(2):291-7.
1995: Rogier Versteeg; H Caron; N C Cheng; Pauline van der Drift; Rosalyn Slater; Andries Westerveld; Paul A Voûte; O Delattre; Geneviève Laureys; Nadine Van Roy
1p36: every subband a suppressor?
European journal of cancer (Oxford, England : 1990) 1995;31A(4):538-41.
1995: Nadine Van Roy; N C Cheng; Geneviève Laureys; G Opdenakker; Rogier Versteeg; Frank Speleman
Molecular cytogenetic analysis of 1;17 translocations in neuroblastoma.
European journal of cancer (Oxford, England : 1990) 1995;31A(4):530-5.
1995: Geneviève Laureys; Rogier Versteeg; Frank Speleman; Pauline van der Drift; U Francke; G Opdenakker; Nadine Van Roy
Characterisation of the chromosome breakpoints in a patient with a constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12) and neuroblastoma.
European journal of cancer (Oxford, England : 1990) 1995;31A(4):523-6.
1994: Pauline van der Drift; A Chan; Nadine Van Roy; Geneviève Laureys; Andries Westerveld; Frank Speleman; Rogier Versteeg
A multimegabase cluster of snRNA and tRNA genes on chromosome 1p36 harbours an adenovirus/SV40 hybrid virus integration site.
Human molecular genetics 1994;3(12):2131-6.
1994: H Caron; P van Sluis; Nadine Van Roy; Jan de Kraker; Frank Speleman; Paul A Voûte; Andries Westerveld; Rosalyn Slater; Rogier Versteeg
Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity.
American journal of human genetics 1994;55(2):341-7.
1994: Nadine Van Roy; Geneviève Laureys; N C Cheng; P Willem; G Opdenakker; Rogier Versteeg; Frank Speleman
1;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines.
Genes, chromosomes & cancer 1994;10(2):103-14.
1993: Nadine Van Roy; Geneviève Laureys; Rogier Versteeg; G Opdenakker; Frank Speleman
High-resolution fluorescence mapping of 46 DNA markers to the short arm of human chromosome 1.
Genomics 1993;18(1):71-8.
1993: H Caron; P van Sluis; M van Hoeve; Jan de Kraker; J Bras; Rosalyn Slater; marcel mannens; Paul A Voûte; Andries Westerveld; Rogier Versteeg
Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification.
Nature genetics 1993;4(2):187-90.
1992: G A Boschman; W Rens; Erik Manders; R M Slater; Rogier Versteeg; Jacob A Aten
Detection of recurrent chromosome abnormalities in Ewing's sarcoma and peripheral neuroectodermal tumor cells using bivariate flow karyotyping.
Genes, chromosomes & cancer 1992;5(4):375-84.
1992: Rogier Versteeg
NK cells and T cells: mirror images?
Immunology today 1992;13(7):244-7.