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Rogier Versteeg
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22
Caron, Huib
19
Speleman, Frank
18
Van Roy, Nadine
14
van Sluis, Peter
14
Koster, Jan
14
Laureys, Geneviève
12
Voûte, Paul
12
Westerveld, Andries
9
van der Drift, Pauline
7
Valentijn, Linda
7
Geerts, Dirk
6
van Noesel, Max
6
Boon, Kathy
5
van Schaik, Barbera
5
Spieker, N
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All Publications
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2009: van Engelen Klaartje; Merks Johannes H M; Lam Jan; Kremer Leontien C M; Backes Manouk; Baars Marieke J H; van der Pal Heleen J H; Postma Alex V; Versteeg Rogier; Caron Huib N; Mulder Barbara J M
Prevalence of congenital heart defects in neuroblastoma patients: a cohort study and systematic review of literature.
European journal of pediatrics 2009;168(9):1081-90.
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2009: Molenaar Jan J; Ebus Marli E; Geerts Dirk; Koster Jan; Lamers Fieke; Valentijn Linda J; Westerhout Ellen M; Versteeg Rogier; Caron Huib N
Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12968-73.
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2009: Stutterheim Janine; Gerritsen Annemieke; Zappeij-Kannegieter Lily; Yalcin Bilgehan; Dee Rob; van Noesel Max M; Berthold Frank; Versteeg Rogier; Caron Huib N; van der Schoot C Ellen; Tytgat Godelieve A M
Detecting minimal residual disease in neuroblastoma: the superiority of a panel of real-time quantitative PCR markers.
Clinical chemistry 2009;55(7):1316-26.
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2009: Schulte Johannes H; Pentek Falk; Hartmann Wolfgang; Schramm Alexander; Friedrichs Nicolaus; Øra Ingrid; Koster Jan; Versteeg Rogier; Kirfel Jutta; Buettner Reinhard; Eggert Angelika
The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo.
International journal of cancer. Journal international du cancer 2009;124(10):2488-94.
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2009: van Hooff Sander R; Koster Jan; Hulsen Tim; van Schaik Barbera D C; Roos Marco; van Batenburg Marcel F; Versteeg Rogier; van Kampen Antoine H C
The construction of genome-based transcriptional units.
Omics : a journal of integrative biology 2009;13(2):105-14.
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2009: Schulte Johannes H; Lim Soyoung; Schramm Alexander; Friedrichs Nicolaus; Koster Jan; Versteeg Rogier; Ora Ingrid; Pajtler Kristian; Klein-Hitpass Ludger; Kuhfittig-Kulle Steffi; Metzger Eric; Schüle Roland; Eggert Angelika; Buettner Reinhard; Kirfel Jutta
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy.
Cancer research 2009;69(5):2065-71.
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2008: de Haas Talitha; Hasselt Nancy; Troost Dirk; Caron Huib; Popovic Mara; Zadravec-Zaletel Lorna; Grajkowska Wieslawa; Perek Marta; Osterheld Maria-Chiara; Ellison David; Baas Frank; Versteeg Rogier; Kool Marcel
Molecular risk stratification of medulloblastoma patients based on immunohistochemical analysis of MYC, LDHB, and CCNB1 expression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(13):4154-60.
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2008: Molenaar Jan J; Ebus Marli E; Koster Jan; van Sluis Peter; van Noesel Carel J M; Versteeg Rogier; Caron Huib N
Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma.
Cancer research 2008;68(8):2599-609.
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2008: Koppen Arjen; Ait-Aissa Rachida; Koster Jan; Øra Ingrid; Bras Johannes; van Sluis Peter G; Caron Huib; Versteeg Rogier; Valentijn Linda J
Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN.
International journal of cancer. Journal international du cancer 2008;122(7):1455-64.
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2008: Revet Ingrid; Huizenga Gerda; Chan Alvin; Koster Jan; Volckmann Richard; van Sluis Peter; Øra Ingrid; Versteeg Rogier; Geerts Dirk
The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma.
Experimental cell research 2008;314(4):707-19.
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2008: Kool Marcel; Koster Jan; Bunt Jens; Hasselt Nancy E; Lakeman Arjan; van Sluis Peter; Troost Dirk; Meeteren Netteke Schouten-van; Caron Huib N; Cloos Jacqueline; Mrsic Alan; Ylstra Bauke; Grajkowska Wieslawa; Hartmann Wolfgang; Pietsch Torsten; Ellison David; Clifford Steven C; Versteeg Rogier
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.
PloS one 2008;3(8):e3088.
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2007: Michels Evi; Vandesompele Jo; De Preter Katleen; Hoebeeck Jasmien; Vermeulen Joëlle; Schramm Alexander; Molenaar Jan J; Menten Björn; Marques Barbara; Stallings Raymond L; Combaret Valérie; Devalck Christine; De Paepe Anne; Versteeg Rogier; Eggert Angelika; Laureys Geneviève; Van Roy Nadine; Speleman Frank
ArrayCGH-based classification of neuroblastoma into genomic subgroups.
Genes, chromosomes & cancer 2007;46(12):1098-108.
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2007: Geerts Dirk; Wallick Christopher J; Koomoa Dana-Lynn T; Koster Jan; Versteeg Rogier; Go Ramon Christopher V; Bachmann André S
Expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in neuroblastoma: correlation with clinical features, cellular localization, and cerulenin-mediated apoptosis regulation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(21):6312-9.
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2007: Koppen Arjen; Ait-Aissa Rachida; Koster Jan; van Sluis Peter G; Ora Ingrid; Caron Huib N; Volckmann Richard; Versteeg Rogier; Valentijn Linda J
Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.
European journal of cancer (Oxford, England : 1990) 2007;43(16):2413-22.
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2007: Koppen Arjen; Ait-Aissa Rachida; Hopman Saskia; Koster Jan; Haneveld Franciska; Versteeg Rogier; Valentijn Linda J
Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation.
Cancer letters 2007;256(2):218-28.
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2007: Gierman Hinco J; Indemans Mireille H G; Koster Jan; Goetze Sandra; Seppen Jurgen; Geerts Dirk; van Driel Roel; Versteeg Rogier
Domain-wide regulation of gene expression in the human genome.
Genome research 2007;17(9):1286-95.
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2007: Goetze Sandra; Mateos-Langerak Julio; Gierman Hinco J; de Leeuw Wim; Giromus Osdilly; Indemans Mireille H G; Koster Jan; Ondrej Vladan; Versteeg Rogier; van Driel Roel
The three-dimensional structure of human interphase chromosomes is related to the transcriptome map.
Molecular and cellular biology 2007;27(12):4475-87.
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2007: Zinner Roman; Teller Kathrin; Versteeg Rogier; Cremer Thomas; Cremer Marion
Biochemistry meets nuclear architecture: multicolor immuno-FISH for co-localization analysis of chromosome segments and differentially expressed gene loci with various histone methylations.
Advances in enzyme regulation 2007;47():223-41.
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2007: Henriksen Jørn R; Løkke Cecilie; Hammerø Martin; Geerts Dirk; Versteeg Rogier; Flaegstad Trond; Einvik Christer
Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines.
Nucleic acids research 2007;35(9):e67.
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2006: Kester Monique H A; Kuiper George G J M; Versteeg Rogier; Visser Theo J
Regulation of type III iodothyronine deiodinase expression in human cell lines.
Endocrinology 2006;147(12):5845-54.
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2006: Valentijn Linda J; Koster Jan; Versteeg Rogier
Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV.
Genomics 2006;87(4):483-9.
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2006: de Haas Talitha; Oussoren Esmeralda; Grajkowska Wieslawa; Perek-Polnik Marta; Popovic Mara; Zadravec-Zaletel Lorna; Perera Marzia; Corte Giorgio; Wirths Oliver; van Sluis Peter; Pietsch Torsten; Troost Dirk; Baas Frank; Versteeg Rogier; Kool Marcel
OTX1 and OTX2 expression correlates with the clinicopathologic classification of medulloblastomas.
Journal of neuropathology and experimental neurology 2006;65(2):176-86.
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2005: van Limpt Vera; Chan Alvin; Schramm Alexander; Eggert Angelika; Versteeg Rogier
Phox2B mutations and the Delta-Notch pathway in neuroblastoma.
Cancer letters 2005;228(1-2):59-63.
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2005: Schramm Alexander; Schulte Johannes H; Astrahantseff Kathy; Apostolov Ognjan; Limpt Vera van; Sieverts Hauke; Kuhfittig-Kulle Steffi; Pfeiffer Petra; Versteeg Rogier; Eggert Angelika
Biological effects of TrkA and TrkB receptor signaling in neuroblastoma.
Cancer letters 2005;228(1-2):143-53.
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2005: Geerts Dirk; Revet Ingrid; Jorritsma Gerda; Schilderink Nathalie; Versteeg Rogier
MEIS homeobox genes in neuroblastoma.
Cancer letters 2005;228(1-2):43-50.
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2005: Valentijn Linda J; Koppen Arjen; van Asperen Ronald; Root Heather A; Haneveld Franciska; Versteeg Rogier
Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, Cdc42, and nm23 genes.
Cancer research 2005;65(8):3136-45.
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2004: van Limpt Vera; Schramm Alexander; van Lakeman Arjan; Sluis Peter; Chan Alvin; van Noesel Max; Baas Frank; Caron Huib; Eggert Angelika; Versteeg Rogier
The Phox2B homeobox gene is mutated in sporadic neuroblastomas.
Oncogene 2004;23(57):9280-8.
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2004: van Noesel Max M; Versteeg Rogier
Pediatric neuroblastomas: genetic and epigenetic 'danse macabre'.
Gene 2004;325():1-15.
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2003: van Noesel Max M; van Bezouw Saskia; Voûte P A; Herman James G; Pieters Rob; Versteeg Rogier
Clustering of hypermethylated genes in neuroblastoma.
Genes, chromosomes & cancer 2003;38(3):226-33.
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2003: Versteeg Rogier; van Schaik Barbera D C; van Batenburg Marinus F; Roos Marco; Monajemi Ramin; Caron Huib; Bussemaker Harmen J; van Kampen Antoine H C
The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes.
Genome research 2003;13(9):1998-2004.
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2003: van Noesel Max M; Pieters Rob; Voûte P A; Versteeg Rogier
The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis.
Cancer letters 2003;197(1-2):165-72.
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2003: Geerts Dirk; Schilderink Nathalie; Jorritsma Gerda; Versteeg Rogier
The role of the MEIS homeobox genes in neuroblastoma.
Cancer letters 2003;197(1-2):87-92.
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2003: Van Limpt Vera A E; Chan Alvin J; Van Sluis Peter G; Caron Huib N; Van Noesel Carel J M; Versteeg Rogier
High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type.
International journal of cancer. Journal international du cancer 2003;105(1):61-9.
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2003: Molenaar Jan J; van Sluis Peter; Boon Kathy; Versteeg Rogier; Caron Huib N
Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma.
Genes, chromosomes & cancer 2003;36(3):242-9.
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2002: Van Roy Nadine; Vandesompele Jo; Berx Geert; Staes Katrien; Van Gele Mireille; De Smet Els; De Paepe Anne; Laureys Geneviève; van der Drift Pauline; Versteeg Rogier; Van Roy Frans; Speleman Frank
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients.
Genes, chromosomes & cancer 2002;35(2):113-20.
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2002: Godfried M B; Veenstra M; Valent A; Sluis P v; Voûte P A; Versteeg R; Caron H N
Lack of interstitial chromosome 1p deletions in clinically-detected neuroblastoma.
European journal of cancer (Oxford, England : 1990) 2002;38(11):1513-9.
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2002: van Noesel Max M; van Bezouw Saskia; Salomons Gajja S; Voûte P A; Pieters Rob; Baylin Steve B; Herman James G; Versteeg Rogier
Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation.
Cancer research 2002;62(7):2157-61.
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2002: Godfried Marc B; Veenstra Monique; v Sluis Peter; Boon Kathy; v Asperen Ronald; Hermus Marie Christien; v Schaik Barbara D C; Voûte Tom P A; Schwab Manfred; Versteeg Rogier; Caron Huib N
The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2.
Oncogene 2002;21(13):2097-101.
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2001: Spieker N; Beitsma M; Van Sluis P; Chan A; Caron H; Versteeg R
Three chromosomal rearrangements in neuroblastoma cluster within a 300-kb region on 1p36.1.
Genes, chromosomes & cancer 2001;31(2):172-81.
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2001: Boon K; Caron H N; van Asperen R; Valentijn L; Hermus M C; van Sluis P; Roobeek I; Weis I; Voûte P A; Schwab M; Versteeg R
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis.
The EMBO journal 2001;20(6):1383-93.
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2001: Caron H; van Schaik B; van der Mee M; Baas F; Riggins G; van Sluis P; Hermus M C; van Asperen R; Boon K; Voûte P A; Heisterkamp S; van Kampen A; Versteeg R
The human transcriptome map: clustering of highly expressed genes in chromosomal domains.
Science (New York, N.Y.) 2001;291(5507):1289-92.
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2001: Caron H; Spieker N; Godfried M; Veenstra M; van Sluis P; de Kraker J; Voûte P; Versteeg R
Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted.
Genes, chromosomes & cancer 2001;30(2):168-74.
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2001: Spieker N; van Sluis P; Beitsma M; Boon K; van Schaik B D; van Kampen A H; Caron H; Versteeg R
The MEIS1 oncogene is highly expressed in neuroblastoma and amplified in cell line IMR32.
Genomics 2001;71(2):214-21.
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2000: van Limpt V; Chan A; Caron H; Sluis P V; Boon K; Hermus M C; Versteeg R
SAGE analysis of neuroblastoma reveals a high expression of the human homologue of the Drosophila Delta gene.
Medical and pediatric oncology 2000;35(6):554-8.
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2000: van Kampen A H; van Schaik B D; Pauws E; Michiels E M; Ruijter J M; Caron H N; Versteeg R; Heisterkamp S H; Leunissen J A; Baas F; van der Mee M
USAGE: a web-based approach towards the analysis of SAGE data. Serial Analysis of Gene Expression.
Bioinformatics (Oxford, England) 2000;16(10):899-905.
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2000: Spieker N; Beitsma M; van Sluis P; Roobeek I; den Dunnen J T; Speleman F; Caron H; Versteeg R
An integrated 5-Mb physical, genetic, and radiation hybrid map of a 1p36.1 region implicated in neuroblastoma pathogenesis.
Genes, chromosomes & cancer 2000;27(2):143-52.
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1999: van der Drift P; Chan A; Zehetner G; Westerveld A; Versteeg R
Multiple MSP pseudogenes in a local repeat cluster on 1p36.2: An expanding genomic graveyard?
Genomics 1999;62(1):74-81.
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1999: Wuyts W; Spieker N; Van Roy N; De Boulle K; De Paepe A; Willems P J; Van Hul W; Versteeg R; Speleman F
Refined physical mapping and genomic structure of the EXTL1 gene.
Cytogenetics and cell genetics 1999;86(3-4):267-70.
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1998: Van Gele M; Van Roy N; Ronan S G; Messiaen L; Vandesompele J; Geerts M L; Naeyaert J M; Blennow E; Bar-Am I; Das Gupta T K; van der Drift P; Versteeg R; Leonard J H; Speleman F
Molecular analysis of 1p36 breakpoints in two Merkel cell carcinomas.
Genes, chromosomes & cancer 1998;23(1):67-71.
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1997: Van Gele M; Van Roy N; Jauch A; Laureys G; Benoit Y; Schelfhout V; De Potter C R; Brock P; Uyttebroeck A; Sciot R; Schuuring E; Versteeg R; Speleman F
Sensitive and reliable detection of genomic imbalances in human neuroblastomas using comparative genomic hybridisation analysis.
European journal of cancer (Oxford, England : 1990) 1997;33(12):1979-82.
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1997: Van Roy N; Laureys G; Van Gele M; Opdenakker G; Miura R; van der Drift P; Chan A; Versteeg R; Speleman F
Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes.
European journal of cancer (Oxford, England : 1990) 1997;33(12):1974-8.
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1997: Van Roy N; Jauch A; Van Gele M; Laureys G; Versteeg R; De Paepe A; Cremer T; Speleman F
Comparative genomic hybridization analysis of human neuroblastomas: detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines.
Cancer genetics and cytogenetics 1997;97(2):135-42.
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1996: Cheng N C; Beitsma M; Chan A; Op den Camp I; Westerveld A; Pronk J; Versteeg R
Lack of class I HLA expression in neuroblastoma is associated with high N-myc expression and hypomethylation due to loss of the MEMO-1 locus.
Oncogene 1996;13(8):1737-44.
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1996: Caron H; van Sluis P; Buschman R; Pereira do Tanque R; Maes P; Beks L; de Kraker J; Voûte P A; Vergnaud G; Westerveld A; Slater R; Versteeg R
Allelic loss of the short arm of chromosome 4 in neuroblastoma suggests a novel tumour suppressor gene locus.
Human genetics 1996;97(6):834-7.
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1996: Cheng N C; Chan A J; Beitsma M M; Speleman F; Westerveld A; Versteeg R
A human modifier of methylation for class I HLA genes (MEMO-1) maps to chromosomal bands 1p35-36.1.
Human molecular genetics 1996;5(3):309-17.
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1996: Hofstra R M; Cheng N C; Hansen C; Stulp R P; Stelwagen T; Clausen N; Tommerup N; Caron H; Westerveld A; Versteeg R; Buys C H
No mutations found by RET mutation scanning in sporadic and hereditary neuroblastoma.
Human genetics 1996;97(3):362-4.
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1996: Caron H; van Sluis P; de Kraker J; Bökkerink J; Egeler M; Laureys G; Slater R; Westerveld A; Voûte P A; Versteeg R
Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma.
The New England journal of medicine 1996;334(4):225-30.
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1995: van der Drift P; Chan A; Laureys G; van Roy N; Sickmann G; den Dunnen J; Westerveld A; Speleman F; Versteeg R
Balanced translocation in a neuroblastoma patient disrupts a cluster of small nuclear RNA U1 and tRNA genes in chromosomal band 1p36.
Genes, chromosomes & cancer 1995;14(1):35-42.
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1995: Van Roy N; Forus A; Myklebost O; Cheng N C; Versteeg R; Speleman F
Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP.
Cancer genetics and cytogenetics 1995;82(2):151-4.
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1995: Laureys G; Speleman F; Versteeg R; van der Drift P; Chan A; Leroy J; Francke U; Opdenakker G; Van Roy N
Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.
Oncogene 1995;10(6):1087-93.
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1995: Cheng N C; Van Roy N; Chan A; Beitsma M; Westerveld A; Speleman F; Versteeg R
Deletion mapping in neuroblastoma cell lines suggests two distinct tumor suppressor genes in the 1p35-36 region, only one of which is associated with N-myc amplification.
Oncogene 1995;10(2):291-7.
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1995: Versteeg R; Caron H; Cheng N C; van der Drift P; Slater R; Westerveld A; Voûte P A; Delattre O; Laureys G; Van Roy N
1p36: every subband a suppressor?
European journal of cancer (Oxford, England : 1990) 1995;31A(4):538-41.
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1995: Van Roy N; Cheng N C; Laureys G; Opdenakker G; Versteeg R; Speleman F
Molecular cytogenetic analysis of 1;17 translocations in neuroblastoma.
European journal of cancer (Oxford, England : 1990) 1995;31A(4):530-5.
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1995: Laureys G; Versteeg R; Speleman F; van der Drift P; Francke U; Opdenakker G; Van Roy N
Characterisation of the chromosome breakpoints in a patient with a constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12) and neuroblastoma.
European journal of cancer (Oxford, England : 1990) 1995;31A(4):523-6.
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1994: van der Drift P; Chan A; van Roy N; Laureys G; Westerveld A; Speleman F; Versteeg R
A multimegabase cluster of snRNA and tRNA genes on chromosome 1p36 harbours an adenovirus/SV40 hybrid virus integration site.
Human molecular genetics 1994;3(12):2131-6.
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1994: Caron H; van Sluis P; van Roy N; de Kraker J; Speleman F; Voûte P A; Westerveld A; Slater R; Versteeg R
Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity.
American journal of human genetics 1994;55(2):341-7.
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1994: Van Roy N; Laureys G; Cheng N C; Willem P; Opdenakker G; Versteeg R; Speleman F
1;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines.
Genes, chromosomes & cancer 1994;10(2):103-14.
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1993: Van Roy N; Laureys G; Versteeg R; Opdenakker G; Speleman F
High-resolution fluorescence mapping of 46 DNA markers to the short arm of human chromosome 1.
Genomics 1993;18(1):71-8.
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1993: Caron H; van Sluis P; van Hoeve M; de Kraker J; Bras J; Slater R; Mannens M; Voûte P A; Westerveld A; Versteeg R
Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification.
Nature genetics 1993;4(2):187-90.
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1992: Boschman G A; Rens W; Manders E M; Slater R M; Versteeg R; Aten J A
Detection of recurrent chromosome abnormalities in Ewing's sarcoma and peripheral neuroectodermal tumor cells using bivariate flow karyotyping.
Genes, chromosomes & cancer 1992;5(4):375-84.
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1992: Versteeg R
NK cells and T cells: mirror images?
Immunology today 1992;13(7):244-7.
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