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Annemieke Verstuyf

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Annemieke Verstuyf; Roger Bouillon
Vitamin D and cancer.
Carlien Leyssens; Lieve Verlinden; Annemieke Verstuyf
Antineoplastic effects of 1,25(OH)2D3 and its analogs in breast, prostate and colorectal cancer.
Roger Bouillon; Annemieke Verstuyf
Vitamin D, mitochondria, and muscle.

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All Publications

2013: Annemieke Verstuyf; Roger Bouillon
Vitamin D and cancer.
Cell cycle (Georgetown, Tex.) 2013;12(7):1018.
2013: Carlien Leyssens; Lieve Verlinden; Annemieke Verstuyf
Antineoplastic effects of 1,25(OH)2D3 and its analogs in breast, prostate and colorectal cancer.
Endocrine-related cancer 2013;20(2):R31-47.
2013: Roger Bouillon; Annemieke Verstuyf
Vitamin D, mitochondria, and muscle.
The Journal of clinical endocrinology and metabolism 2013;98(3):961-3.
2012: Heidi Wolden-Kirk; Annemieke Verstuyf; Conny Gysemans; Chantal Mathieu
Extraskeletal effects of vitamin D.
Endocrinology and metabolism clinics of North America 2012;41(3):571-94.
2012: Verónica Gonzalez-Pardo; Ricardo Boland; Noelia D'Elia; Annemieke Verstuyf; Ana Russo De Boland
NFκB pathway is down-regulated by 1α,25(OH)(2)-vitamin D(3) in endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein coupled receptor.
Steroids 2012;77(11):1025-32.
2012: Sigrid Hatse; Carsten Kriebitzsch; Annouschka Laenen; Diether Lambrechts; Patrick Neven; Robert Paridaens; Gilian Peuteman; Ann Smeets; Thijs Vandorpe; Lieve Verlinden; Annemieke Verstuyf; Roger Bouillon; Olivier Brouckaert; Barbara Brouwers; Marie-Rose Christiaens; Anne-Sophie Dieudonné; Hans Wildiers
Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome, and genetic determinants of vitamin D insufficiency.
Carcinogenesis 2012;33(7):1319-26.
2012: Isabelle Clinckspoor; Pierre Delaere; Esther Hauben; Chantal Mathieu; Annick Van den Bruel; Vincent Vander Poorten; Lieve Vanwalleghem; Lieve Verlinden; Annemieke Verstuyf; Brigitte Decallonne
Altered expression of key players in vitamin D metabolism and signaling in malignant and benign thyroid tumors.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2012;60(7):502-11.
2012: Christine Helsen; Arnaud Marchand; Sebastian Munck; Annemieke Verstuyf; Arnout Voet; Patrick Chaltin; Frank Claessens
Identification and characterization of MEL-3, a novel AR antagonist that suppresses prostate cancer cell growth.
Molecular cancer therapeutics 2012;11(6):1257-68.
2012: Bart J Van der Schueren; Annemieke Verstuyf; Chantal Mathieu
Straight from D-Heart: vitamin D status and cardiovascular disease.
Current opinion in lipidology 2012;23(1):17-23.
2011: Carsten Kriebitzsch; Paul Lips; Mark B Meyer; J Wesley Pike; Karin Swart; Natasja M van Schoor; Lieve Verlinden; Ruma Banerjee; Steven Boonen; Roger Bouillon; Carsten Carlberg; Guy Eelen; Victor M Vitvitsky; Annemieke Verstuyf
1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(12):2991-3000.
2011: Gabriela Bomfim Ferreira; Conny Gysemans; Lut Overbergh; Evelyne van Etten; Annemieke Verstuyf; Mark Waer; Chantal Mathieu
1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivo.
Diabetes/metabolism research and reviews 2011;27(8):933-41.
2011: E Vanoirbeek; Lieve Verlinden; Roger Bouillon; Guy Eelen; D Feldman; A Krishnan; Annemieke Verstuyf
The anti-cancer and anti-inflammatory actions of 1,25(OH)₂D₃.
Best practice & research. Clinical endocrinology & metabolism 2011;25(4):593-604.
2011: Lieve Verlinden; Annemieke Verstuyf; Guy Eelen; Roger Bouillon; Paloma Ordóñez-Morán; María Jesús Larriba; Alberto Muñoz; Natacha Rochel; Yoshiteru Sato; Dino Moras; Miguel Maestro; Samuel Seoane; Fernando Dominguez; Silvina Eduardo-Canosa; Daniel Nicoletti; Edelmiro Moman; Antonio Mouriño
Synthesis, structure, and biological activity of des-side chain analogues of 1α,25-dihydroxyvitamin D3 with substituents at C18.
ChemMedChem 2011;6(5):788-93.
2011: Isabelle Clinckspoor; Lieve Verlinden; Lut Overbergh; Christopher Korch; Roger Bouillon; Chantal Mathieu; Annemieke Verstuyf; Brigitte Decallonne
1,25-dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer.
The Journal of steroid biochemistry and molecular biology 2011;124(1-2):1-9.
2011: Evelien Gielen; Koen Milisen; Mieke Sinnesael; Dirk Vanderschueren; Steven Boonen; Frank Claessens; Annemieke Verstuyf; Sabine Verschueren
Calcium and vitamin d supplementation in men.
Journal of osteoporosis 2011;2011():875249.
2011: Femke Baeke; Hannelie Korf; Lut Overbergh; Annemieke Verstuyf; Lieven Thorrez; Leentje Van Lommel; Mark Waer; Frans Schuit; Conny Gysemans; Chantal Mathieu
The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(1):132-42.
2010: Christopher M Baker; Annemieke Verstuyf; Kim B Jensen; Fiona M Watt
Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation.
Developmental biology 2010;343(1-2):40-50.
2010: Femke Baeke; Hannelie Korf; Lut Overbergh; Evelyne van Etten; Annemieke Verstuyf; Conny Gysemans; Chantal Mathieu
Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D3 in the immune system.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):221-7.
2010: Annemieke Verstuyf; Geert Carmeliet; Roger Bouillon; Chantal Mathieu
Vitamin D: a pleiotropic hormone.
Kidney international 2010;78(2):140-5.
2010: Guy Eelen; Lieve Verlinden; Roger Bouillon; Pierre J De Clercq; Alberto Muñoz; Annemieke Verstuyf
CD-ring modified vitamin D3 analogs and their superagonistic action.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):417-9.
2010: Valerie Storms; Marleen Claeys; Aminael Sanchez; Bart De Moor; Annemieke Verstuyf; Kathleen Marchal
The effect of orthology and coregulation on detecting regulatory motifs.
PloS one 2010;5(2):e8938.
2010: Verónica Gonzalez-Pardo; Daniel Martin; J Silvio Gutkind; Annemieke Verstuyf; Roger Bouillon; Ana Russo De Boland; Ricardo L Boland
1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo.
Endocrinology 2010;151(1):23-31.
2009: Laura Sánchez-Abella; Susana Fernández; Annemieke Verstuyf; Lieve Verlinden; Vicente Gotor; Miguel Ferrero
Synthesis, conformational analysis, and biological evaluation of 19-nor-vitamin D3 analogues with A-ring modifications.
Journal of medicinal chemistry 2009;52(19):6158-62.
2009: Els Vanoirbeek; Guy Eelen; Lieve Verlinden; Kathleen Marchal; Kristof Engelen; Bart De Moor; Ine Beullens; Suzanne Marcelis; Pierre J De Clercq; Roger Bouillon; Annemieke Verstuyf
Microarray analysis of MCF-7 breast cancer cells treated with 1,25-dihydroxyvitamin D3 or a 17-methyl-D-ring analog.
Anticancer research 2009;29(9):3585-90.
2009: Guy Eelen; Lieve Verlinden; JM Laureys; Suzanne Marcelis; Pierre J De Clercq; Chantal Mathieu; Roger Bouillon; Annemieke Verstuyf
Antiproliferative and calcemic actions of trans-decalin CD-ring analogs of 1,25-dihydroxyvitamin D3.
Anticancer research 2009;29(9):3579-84.
2009: Carsten Kriebitzsch; Lieve Verlinden; Guy Eelen; Biauw Keng Tan; Mark Van Camp; Roger Bouillon; Annemieke Verstuyf
The impact of 1,25(OH)2D3 and its structural analogs on gene expression in cancer cells--a microarray approach.
Anticancer research 2009;29(9):3471-83.
2009: Gabriela Bomfim Ferreira; Evelyne van Etten; Kasper Lage; Daniel Aaen Hansen; Yves Moreau; Christopher T Workman; Mark Waer; Annemieke Verstuyf; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D.
Proteomics 2009;9(14):3752-64.
2009: Garrett Minne; Lieve Verlinden; Annemieke Verstuyf; Pierre J De Clercq
Synthesis of 1alpha,25-dihydroxyvitamin D analogues featuring a S(2)-symmetric CD-ring core.
Molecules (Basel, Switzerland) 2009;14(2):894-903.
2009: Hong Sun; Tijl De Bie; Valerie Storms; Qiang Fu; Thomas Dhollander; Karen Lemmens; Annemieke Verstuyf; Bart De Moor; Kathleen Marchal
ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules.
BMC bioinformatics 2009;10 Suppl 1():S30.
2008: Laura Sánchez-Abella; Susana Fernández; Annemieke Verstuyf; Lieve Verlinden; Vicente Gotor; Miguel Ferrero
Synthesis and biological activity of previtamin D(3) analogues with A-ring modifications.
Bioorganic & medicinal chemistry 2008;16(24):10244-50.
2008: Guy Eelen; Noelia Valle; Yoshiteru Sato; Natacha Rochel; Lieve Verlinden; Pierre J De Clercq; Dino Moras; Roger Bouillon; Alberto Muñoz; Annemieke Verstuyf
Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor.
Chemistry & biology 2008;15(10):1029-34.
2008: Roger Bouillon; Geert Carmeliet; Lieve Verlinden; Evelyne van Etten; Annemieke Verstuyf; Hilary F Luderer; Liesbet Lieben; Chantal Mathieu; Marie Demay
Vitamin D and human health: lessons from vitamin D receptor null mice.
Endocrine reviews 2008;29(6):726-76.
2008: Conny Gysemans; Evelyne van Etten; Lut Overbergh; Annapaula Giulietti; Guy Eelen; Mark Waer; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor.
Diabetes 2008;57(1):269-75.
2007: Lieve Verlinden; Isabelle Vanden Bempt; Guy Eelen; Maria Drijkoningen; Ilse Verlinden; Kathleen Marchal; Christiane De Wolf-Peeters; Marie-Rose Christiaens; Luc Michiels; Roger Bouillon; Annemieke Verstuyf
The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas.
Cancer research 2007;67(14):6574-81.
2007: Laura Sánchez-Abella; Susana Fernández; Annemieke Verstuyf; Lieve Verlinden; Miguel Ferrero; Vicente Gotor
Synthesis and biological evaluation of new 6-s-cis locked 1,2,25-trihydroxyprevitamin D3 analogues.
Bioorganic & medicinal chemistry 2007;15(12):4193-202.
2007: G Satyanarayana Reddy; Matthew Robinson; Guochun Wang; G Tayhas R Palmore; Lynn Gennaro; Paul Vouros; Pierre J De Clercq; Maurits Vandewalle; Wu Young; Shi Ling; Annemieke Verstuyf; Roger Bouillon
Removal of C-ring from the CD-ring skeleton of 1alpha,25-dihydroxyvitamin D3 does not alter its target tissue metabolism significantly.
Archives of biochemistry and biophysics 2007;460(2):254-61.
2007: Evelyne van Etten; Conny Gysemans; Dumitru D Branisteanu; Annemieke Verstuyf; Roger Bouillon; Lut Overbergh; Chantal Mathieu
Novel insights in the immune function of the vitamin D system: synergism with interferon-beta.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):546-51.
2007: Lieve Verlinden; Guy Eelen; Ruth Van Hellemont; Kristof Engelen; Ine Beullens; Mark Van Camp; Kathleen Marchal; Chantal Mathieu; Roger Bouillon; Annemieke Verstuyf
1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):411-5.
2007: Pierre J De Clercq; Frederik De Buysser; Garrett Minne; Wim Schepens; Freek Vrielynck; Dirk Van Haver; Maurits Vandewalle; Annemieke Verstuyf; Roger Bouillon
The development of CD-ring modified analogs of 1alpha,25-dihydroxyvitamin D.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):206-12.
2007: Evelyne van Etten; Lieve Verlinden; Annapaula Giulietti; Elizabeth Ramos Lopez; Dumitru D Branisteanu; Gabriela B Ferreira; Lut Overbergh; Annemieke Verstuyf; Roger Bouillon; Bart O Roep; Klaus Badenhoop; Chantal Mathieu
The vitamin D receptor gene FokI polymorphism: functional impact on the immune system.
European journal of immunology 2007;37(2):395-405.
2007: Guy Eelen; Conny Gysemans; Lieve Verlinden; E Vanoirbeek; Pierre J De Clercq; Dirk Van Haver; Chantal Mathieu; Roger Bouillon; Annemieke Verstuyf
Mechanism and potential of the growth-inhibitory actions of vitamin D and ana-logs.
Current medicinal chemistry 2007;14(17):1893-910.
2007: Maria Stio; Maria Martinesi; Sara Bruni; Cristina Treves; Chantal Mathieu; Annemieke Verstuyf; Giuseppe d'Albasio; Silvia Bagnoli; Andrea G Bonanomi
The Vitamin D analogue TX 527 blocks NF-kappaB activation in peripheral blood mononuclear cells of patients with Crohn's disease.
The Journal of steroid biochemistry and molecular biology 2007;103(1):51-60.
2006: Roger Bouillon; Annemieke Verstuyf; Chantal Mathieu; Sophie van Cromphaut; Ritsuko Masuyama; Petra Dehaes; Geert Carmeliet
Vitamin D resistance.
Best practice & research. Clinical endocrinology & metabolism 2006;20(4):627-45.
2006: Roger Bouillon; Guy Eelen; Lieve Verlinden; Chantal Mathieu; Geert Carmeliet; Annemieke Verstuyf
Vitamin D and cancer.
The Journal of steroid biochemistry and molecular biology 2006;102(1-5):156-62.
2006: Daniel Oves; Susana Fernández; Lieve Verlinden; Roger Bouillon; Annemieke Verstuyf; Miguel Ferrero; Vicente Gotor
Novel A-ring homodimeric C-3-carbamate analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation.
Bioorganic & medicinal chemistry 2006;14(22):7512-9.
2006: Wim Schepens; Dirk Van Haver; Maurits Vandewalle; Roger Bouillon; Annemieke Verstuyf; Pierre J De Clercq
Synthesis of spiro[4.5]decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D3.
Organic letters 2006;8(19):4247-50.
2006: Lut Overbergh; Katinka Stoffels; Mark Waer; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction.
The Journal of clinical endocrinology and metabolism 2006;91(9):3566-74.
2006: Guy Eelen; Lieve Verlinden; Pierre J De Clercq; Maurits Vandewalle; Roger Bouillon; Annemieke Verstuyf
Vitamin D analogs and coactivators.
Anticancer research 2006;26(4A):2717-21.
2006: Daniel Oves; Susana Fernández; Miguel Ferrero; Roger Bouillon; Annemieke Verstuyf; Vicente Gotor
Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1alpha,25-dihydroxyvitamin D3 analogues.
Bioorganic & medicinal chemistry 2006;14(4):928-37.
2005: Lieve Verlinden; Guy Eelen; Ine Beullens; Mark Van Camp; Paul van Hummelen; Kristof Engelen; Ruth Van Hellemont; Kathleen Marchal; Bart De Moor; Floris Foijer; Hein te Riele; Monique Beullens; Mathieu Bollen; Chantal Mathieu; Roger Bouillon; Annemieke Verstuyf
Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.
The Journal of biological chemistry 2005;280(45):37319-30.
2005: Roger Bouillon; Lieve Verlinden; Guy Eelen; Pierre J De Clercq; Maurits Vandewalle; Chantal Mathieu; Annemieke Verstuyf
Mechanisms for the selective action of Vitamin D analogs.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):21-30.
2005: Guy Eelen; Lieve Verlinden; Mark Van Camp; Frank Claessens; Pierre J De Clercq; Maurits Vandewalle; Roger Bouillon; Annemieke Verstuyf
Altered Vitamin D receptor-coactivator interactions reflect superagonism of Vitamin D analogs.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):65-8.
2005: Guy Eelen; Lieve Verlinden; Natacha Rochel; Frank Claessens; Pierre J De Clercq; Maurits Vandewalle; Giuseppe Tocchini-Valentini; Dino Moras; Roger Bouillon; Annemieke Verstuyf
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.
Molecular pharmacology 2005;67(5):1566-73.
2005: Petra De Haes; Marjan Garmyn; Annemieke Verstuyf; Pierre J De Clercq; Maurits Vandewalle; Hugo Degreef; Katleen Vantieghem; Roger Bouillon; Siegfried Segaert
1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage.
Journal of photochemistry and photobiology. B, Biology 2005;78(2):141-8.
2004: Vicente Gotor-Fernández; Susana Fernández; Miguel Ferrero; Vicente Gotor; Roger Bouillon; Annemieke Verstuyf
Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1alpha,25-dihydroxyvitamin D3.
Bioorganic & medicinal chemistry 2004;12(20):5443-51.
2004: Wim Schepens; Dirk Van Haver; Maurits Vandewalle; Pierre J De Clercq; Roger Bouillon; Annemieke Verstuyf
Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: spiro[5.5]undecane CF-ring analogues.
Bioorganic & medicinal chemistry letters 2004;14(15):3889-92.
2004: Samuël Demin; Dirk Van Haver; Maurits Vandewalle; Pierre J De Clercq; Roger Bouillon; Annemieke Verstuyf
Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues.
Bioorganic & medicinal chemistry letters 2004;14(15):3885-8.
2004: Guy Eelen; Lieve Verlinden; Mark Van Camp; Chantal Mathieu; Geert Carmeliet; Roger Bouillon; Annemieke Verstuyf
Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):405-7.
2004: Pierre J De Clercq; Ibrahim Murad; Ling-Jie Gao; Yong-Jun Chen; Dirk Van Haver; Maurits Vandewalle; Annemieke Verstuyf; Lieve Verlinden; Christel Verboven; Roger Bouillon
Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1alpha,25-dihydroxyvitamin D analogs.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):61-6.
2004: Petra De Haes; Marjan Garmyn; Annemieke Verstuyf; Pierre J De Clercq; Maurits Vandewalle; Katleen Vantieghem; Hugo Degreef; Roger Bouillon; Siegfried Segaert
Two 14-epi analogues of 1,25-dihydroxyvitamin D3 protect human keratinocytes against the effects of UVB.
Archives of dermatological research 2004;295(12):527-34.
2004: Guy Eelen; Lieve Verlinden; Mark Van Camp; Paul van Hummelen; Kathleen Marchal; Bart De Moor; Chantal Mathieu; Geert Carmeliet; Roger Bouillon; Annemieke Verstuyf
The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(1):133-46.
2003: Lieve Verlinden; Annemieke Verstuyf; Christel Verboven; Guy Eelen; Camiel J De Ranter; Ling-Jie Gao; Yong-Jun Chen; Ibrahim Murad; Mihwa Choi; Keiko Yamamoto; Sachiko Yamada; Dirk Van Haver; Maurits Vandewalle; Pierre J De Clercq; Roger Bouillon
Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity.
The Journal of biological chemistry 2003;278(37):35476-82.
2003: Evelyne van Etten; Dumitru D Branisteanu; Lut Overbergh; Roger Bouillon; Annemieke Verstuyf; Chantal Mathieu
Combination of a 1,25-dihydroxyvitamin D3 analog and a bisphosphonate prevents experimental autoimmune encephalomyelitis and preserves bone.
Bone 2003;32(4):397-404.
2003: Evelyne van Etten; Brigitte Decallonne; Lieve Verlinden; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Analogs of 1alpha,25-dihydroxyvitamin D3 as pluripotent immunomodulators.
Journal of cellular biochemistry 2003;88(2):223-6.
2003: Yong-Jun Chen; Ling-Jie Gao; Ibrahim Murad; Annemieke Verstuyf; Lieve Verlinden; Christel Verboven; Roger Bouillon; Davide Viterbo; Marco Milanesio; Dirk Van Haver; Maurits Vandewalle; Pierre J De Clercq
Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs.
Organic & biomolecular chemistry 2003;1(2):257-67.
2003: Roger Bouillon; Annemieke Verstuyf; Lieve Verlinden; Guy Eelen; Chantal Mathieu
Prospects for vitamin D receptor modulators as candidate drugs for cancer and (auto)immune diseases.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():353-6.
2002: Yan Ji; Andrzej Kutner; Annemieke Verstuyf; Lieve Verlinden; George P Studzinski
Derivatives of vitamins D2 and D3 activate three MAPK pathways and upregulate pRb expression in differentiating HL60 cells.
Cell cycle (Georgetown, Tex.) 2002;1(6):410-5.
2002: Yusheng Wu; Pierre J De Clercq; Maurits Vandewalle; Roger Bouillon; Annemieke Verstuyf
Vitamin D(3): synthesis of seco-C-9,11-bisnor-17-methyl-1 alpha,25-dihydroxyvitamin D(3) analogues.
Bioorganic & medicinal chemistry letters 2002;12(12):1633-6.
2002: Yusheng Wu; Katrien Sabbe; Pierre J De Clercq; Maurits Vandewalle; Roger Bouillon; Annemieke Verstuyf
Vitamin D(3): synthesis of seco C-9,11,21-trisnor-17-methyl-1 alpha, 25-dihydroxyvitamin D(3) analogues.
Bioorganic & medicinal chemistry letters 2002;12(12):1629-32.
2002: Conny Gysemans; Evelyne van Etten; Lut Overbergh; Annemieke Verstuyf; Mark Waer; Roger Bouillon; Chantal Mathieu
Treatment of autoimmune diabetes recurrence in non-obese diabetic mice by mouse interferon-beta in combination with an analogue of 1alpha,25-dihydroxyvitamin-D3.
Clinical and experimental immunology 2002;128(2):213-20.
2002: Liesbeth Vandenput; Johannes V Swinnen; Erik Van Herck; Annemieke Verstuyf; Steven Boonen; Roger Bouillon; Dirk Vanderschueren
The estrogen receptor ligand ICI 182,780 does not impair the bone-sparing effects of testosterone in the young orchidectomized rat model.
Calcified tissue international 2002;70(3):170-5.
2001: Chantal Mathieu; Evelyne van Etten; Conny Gysemans; Brigitte Decallonne; S Kato; JM Laureys; J Depovere; Dirk Valckx; Annemieke Verstuyf; Roger Bouillon
In vitro and in vivo analysis of the immune system of vitamin D receptor knockout mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(11):2057-65.
2001: Liesbeth Vandenput; Antwan Ederveen; Reinhold Erben; Kerstin Stahr; Johannes V Swinnen; Erik Van Herck; Annemieke Verstuyf; Steven Boonen; Roger Bouillon; Dirk Vanderschueren
Testosterone prevents orchidectomy-induced bone loss in estrogen receptor-alpha knockout mice.
Biochemical and biophysical research communications 2001;285(1):70-6.
2001: Evelyne van Etten; Conny Gysemans; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Immunomodulatory properties of a 1,25(OH)(2) vitamin D(3) analog combined with IFNbeta in an animal model of syngeneic islet transplantation.
Transplantation proceedings 2001;33(3):2319.
2001: Lieve Verlinden; Annemieke Verstuyf; Marcus Quack; Mark Van Camp; Evelyne van Etten; Pierre J De Clercq; Maurits Vandewalle; Carsten Carlberg; Roger Bouillon
Interaction of two novel 14-epivitamin D3 analogs with vitamin D3 receptor-retinoid X receptor heterodimers on vitamin D3 responsive elements.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(4):625-38.
2001: S Gabriëls; Dirk Van Haver; Maurits Vandewalle; Pierre J De Clercq; Annemieke Verstuyf; Roger Bouillon
Development of analogues of 1alpha,25-dihydroxyvitamin D3 with biased side chain orientation: methylated des-C,D-homo analogues.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(2):520-32.
2000: Dirk Vanderschueren; Steven Boonen; Antwan Ederveen; R de Coster; Erik Van Herck; Karen Moermans; Liesbeth Vandenput; Annemieke Verstuyf; Roger Bouillon
Skeletal effects of estrogen deficiency as induced by an aromatase inhibitor in an aged male rat model.
Bone 2000;27(5):611-7.
2000: Evis Daci; Annemieke Verstuyf; Karen Moermans; Roger Bouillon; Geert Carmeliet
Mice lacking the plasminogen activator inhibitor 1 are protected from trabecular bone loss induced by estrogen deficiency.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(8):1510-6.
2000: Evis Daci; Annemieke Verstuyf; Karen Moermans; Roger Bouillon; Geert Carmeliet
Bone resorption induced by 1 alpha,25 dihydroxyvitamin D(3) in vivo is not altered by inactivation of the plasminogen activator inhibitor 1.
Bone 2000;27(1):97-102.
2000: Evelyne van Etten; Dumitru D Branisteanu; Annemieke Verstuyf; Mark Waer; Roger Bouillon; Chantal Mathieu
Analogs of 1,25-dihydroxyvitamin D3 as dose-reducing agents for classical immunosuppressants.
Transplantation 2000;69(9):1932-42.
2000: Lieve Verlinden; Annemieke Verstuyf; Mark Van Camp; S Marcelis; Katrien Sabbe; X Y Zhao; Pierre J De Clercq; Maurits Vandewalle; Roger Bouillon
Two novel 14-Epi-analogues of 1,25-dihydroxyvitamin D3 inhibit the growth of human breast cancer cells in vitro and in vivo.
Cancer research 2000;60(10):2673-9.
2000: Lut Overbergh; Brigitte Decallonne; Dirk Valckx; Annemieke Verstuyf; J Depovere; JM Laureys; Omer Rutgeerts; R Saint-Arnaud; Roger Bouillon; Chantal Mathieu
Identification and immune regulation of 25-hydroxyvitamin D-1-alpha-hydroxylase in murine macrophages.
Clinical and experimental immunology 2000;120(1):139-46.
2000: Annemieke Verstuyf; Siegfried Segaert; Lieve Verlinden; Roger Bouillon; C Mathieu
Recent developments in the use of vitamin D analogues.
Expert opinion on investigational drugs 2000;9(3):443-55.
2000: Annemieke Verstuyf; Lieve Verlinden; Evelyne van Etten; L Shi; Y Wu; C D'Halleweyn; Dirk Van Haver; G D Zhu; Yong-Jun Chen; X Zhou; M R Haussler; Pierre J De Clercq; Maurits Vandewalle; Hugo Van Baelen; Chantal Mathieu; Roger Bouillon
Biological activity of CD-ring modified 1alpha,25-dihydroxyvitamin D analogues: C-ring and five-membered D-ring analogues.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(2):237-52.
1999: X Zhou; G D Zhu; Dirk Van Haver; Maurits Vandewalle; Pierre J De Clercq; Annemieke Verstuyf; Roger Bouillon
Synthesis, biological activity, and conformational analysis of four seco-D-15,19-bisnor-1alpha,25-dihydroxyvitamin D analogues, diastereomeric at C17 and C20.
Journal of medicinal chemistry 1999;42(18):3539-56.
1999: Annemieke Verstuyf; Lieve Verlinden; Siegfried Segaert; Evelyne van Etten; C Mathieu; R Bouillon
Nonclassical effects of 1alpha,25-dihydroxyvitamin D(3) and its analogs.
Mineral and electrolyte metabolism 1999;25(4-6):345-8.
1998: Lieve Verlinden; Annemieke Verstuyf; R Convents; S Marcelis; Mark Van Camp; Roger Bouillon
Action of 1,25(OH)2D3 on the cell cycle genes, cyclin D1, p21 and p27 in MCF-7 cells.
Molecular and cellular endocrinology 1998;142(1-2):57-65.
1998: Annemieke Verstuyf; Siegfried Segaert; Lieve Verlinden; Kristina Casteels; Roger Bouillon; Chantal Mathieu
Recent developments in the use of vitamin D analogues.
Current opinion in nephrology and hypertension 1998;7(4):397-403.
1998: Annemieke Verstuyf; Lieve Verlinden; Hugo Van Baelen; Katrien Sabbe; C D'Hallewyn; Pierre J De Clercq; Maurits Vandewalle; Roger Bouillon
The biological activity of nonsteroidal vitamin D hormone analogs lacking both the C- and D-rings.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(4):549-58.
1998: Roger Bouillon; Geert Carmeliet; Evis Daci; Siegfried Segaert; Annemieke Verstuyf
Vitamin D metabolism and action.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1998;8 Suppl 2():S13-9.
1997: Lieve Verlinden; Annemieke Verstuyf; Chantal Mathieu; B K Tan; Roger Bouillon
Differentiation induction of HL60 cells by 1,25(OH)2D3, all trans retinoic acid, rTGF-beta2 and their combinations.
The Journal of steroid biochemistry and molecular biology 1997;60(1-2):87-97.
1996: J Zhao; B K Tan; S Marcelis; Annemieke Verstuyf; Roger Bouillon
Enhancement of antiproliferative activity of 1alpha,25-dihydroxyvitamin D3 (analogs) by cytochrome P450 enzyme inhibitors is compound- and cell-type specific.
The Journal of steroid biochemistry and molecular biology 1996;57(3-4):197-202.
1996: Roger Bouillon; Annemieke Verstuyf; J Zhao; B K Tan; H Van Baelen
Nonhypercalcemic vitamin D analogs: interactions with the vitamin D-binding protein.
Hormone research 1996;45(3-5):117-21.
1995: Roger Bouillon; Annemieke Verstuyf; Lieve Verlinden; K Allewaert; D Branisteanu; Chantal Mathieu; H van Baelen
Non-hypercalcemic pharmacological aspects of vitamin D analogs.
Biochemical pharmacology 1995;50(5):577-83.
1995: Roger Bouillon; Marjan Garmyn; Annemieke Verstuyf; Siegfried Segaert; Kristina Casteels; Chantal Mathieu
Paracrine role for calcitriol in the immune system and skin creates new therapeutic possibilities for vitamin D analogs.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(1):7-16.
1995: Annemieke Verstuyf; Chantal Mathieu; Lieve Verlinden; Mark Waer; B K Tan; Roger Bouillon
Differentiation induction of human leukemia cells (HL60) by a combination of 1,25-dihydroxyvitamin D3 and retinoic acid (all trans or 9-cis).
The Journal of steroid biochemistry and molecular biology 1995;53(1-6):431-41.
1995: Jan Balzarini; Annemieke Verstuyf; Sigrid Hatse; Jozef Goebels; H Sobis; Michel Vandeputte; E De Clercq
The human immunodeficiency virus(HIV) inhibitor 9-(2-phosphonylmethoxyethyl)adenine (PMEA) is a strong inducer of differentiation of several tumor cell lines.
International journal of cancer. Journal international du cancer 1995;61(1):130-7.
1995: Roger Bouillon; Annemieke Verstuyf; D Branisteanu; Mark Waer; Chantal Mathieu
[Immune modulation by vitamin D analogs in the prevention of autoimmune diseases].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1995;57(5):371-85; discussion 385-7.
1993: H Sobis; Annemieke Verstuyf; Michel Vandeputte
Visceral yolk sac-derived tumors.
The International journal of developmental biology 1993;37(1):155-68.
1993: Annemieke Verstuyf; Jozef Goebels; H Sobis; Michel Vandeputte
Influence of different growth factors on a rat choriocarcinoma cell line.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1993;14(1):46-54.
1992: Annemieke Verstuyf; E Fonteyn; H Sobis; Michel Vandeputte
A rat cytotrophoblast antigen defined by a monoclonal antibody.
American journal of reproductive immunology (New York, N.Y. : 1989) 1992;28(1):6-11.
1991: H Sobis; Annemieke Verstuyf; Michel Vandeputte
Histochemical differences in expression of X-linked glucose-6-phosphate dehydrogenase between ectoderm- and endoderm-derived embryonic and extra-embryonic tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1991;39(5):569-74.
1991: H Sobis; Annemieke Verstuyf; Michel Vandeputte
Endodermal origin of yolk-sac-derived teratomas.
Development (Cambridge, England) 1991;111(1):75-8.
1990: Annemieke Verstuyf; H Sobis; Jozef Goebels; E Fonteyn; J J Cassiman; Michel Vandeputte
Establishment and characterization of a continuous in vitro line from a rat choriocarcinoma.
International journal of cancer. Journal international du cancer 1990;45(4):752-6.
1989: Annemieke Verstuyf; H Sobis; Michel Vandeputte
Morphological and immunological characteristics of a rat choriocarcinoma.
International journal of cancer. Journal international du cancer 1989;44(5):879-84.
1989: H Sobis; Annemieke Verstuyf; Michel Vandeputte
Nature of the multipotential cells in the displaced rat yolk sac.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1989;10(3):140-8.