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Zinaida Vexler

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Cindy T J van Velthoven; Zinaida S Vexler; Hanneke L D M Willemen; nikita derugin; Cobi J Heijnen; Annemieke Kavelaars; Mirjam Maas; R Ann Sheldon; Donna M Ferriero
Mesenchymal stem cell transplantation attenuates brain injury after neonatal stroke.
Moon-Sook Woo; Ping Zhou; Xia Wang; Michael F Wendland; nikita derugin; Joel V Faustino; costantino iadecola; Zinaida S Vexler
Genetic deletion of CD36 enhances injury after acute neonatal stroke.
David Fernández-López; Sarah Y Lee; Richard Daneman; nikita derugin; Joel Faustino; Michael F Wendland; Lu Zhou; Zinaida S Vexler
Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat.

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2013: Cindy T J van Velthoven; Zinaida S Vexler; Hanneke L D M Willemen; nikita derugin; Cobi J Heijnen; Annemieke Kavelaars; Mirjam Maas; R Ann Sheldon; Donna M Ferriero
Mesenchymal stem cell transplantation attenuates brain injury after neonatal stroke.
Stroke; a journal of cerebral circulation 2013;44(5):1426-32.
2012: Moon-Sook Woo; Ping Zhou; Xia Wang; Michael F Wendland; nikita derugin; Joel V Faustino; costantino iadecola; Zinaida S Vexler
Genetic deletion of CD36 enhances injury after acute neonatal stroke.
Annals of neurology 2012;72(6):961-70.
2012: David Fernández-López; Sarah Y Lee; Richard Daneman; nikita derugin; Joel Faustino; Michael F Wendland; Lu Zhou; Zinaida S Vexler
Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(28):9588-600.
2012: D Fernández-López; I Lizasoain; M A Moro; nikita derugin; J Faustino; Michael Wendland; Zinaida S Vexler
Reduced infarct size and accumulation of microglia in rats treated with WIN 55,212-2 after neonatal stroke.
Neuroscience 2012;207():307-15.
2011: Joel V Faustino; Cali E Johnson; Alexander Klibanov; Xia Wang; Michael F Wendland; nikita derugin; Zinaida S Vexler
Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(36):12992-3001.
2011: Karen J Bowers; Gabrielle DeVeber; Donna M Ferriero; E Steve Roach; Zinaida S Vexler; Bernard L Maria
Cerebrovascular disease in children: recent advances in diagnosis and management.
Journal of child neurology 2011;26(9):1074-100.
2011: Mark Dzietko; Donna M Ferriero; nikita derugin; Michael Wendland; Zinaida S Vexler
Magnetic resonance imaging (MRI) as a translational tool for the study of neonatal stroke.
Journal of child neurology 2011;26(9):1145-53.
2011: Valerie Biran; Vivi M Heine; Catherine Verney; R Ann Sheldon; Ruggero Spadafora; Zinaida S Vexler; David H Rowitch; Donna M Ferriero
Cerebellar abnormalities following hypoxia alone compared to hypoxic-ischemic forebrain injury in the developing rat brain.
Neurobiology of disease 2011;41(1):138-46.
2010: Brandon Davis; Jun Tang; Li Zhang; Dezhi Mu; Xiangning Jiang; Valerie Biran; Zinaida S Vexler; Donna M Ferriero
Role of vasodilator stimulated phosphoprotein in VEGF induced blood-brain barrier permeability in endothelial cell monolayers.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2010;28(6):423-8.
2010: Janet Shimotake; nikita derugin; Michael Wendland; Zinaida S Vexler; Donna M Ferriero
Vascular endothelial growth factor receptor-2 inhibition promotes cell death and limits endothelial cell proliferation in a neonatal rodent model of stroke.
Stroke; a journal of cerebral circulation 2010;41(2):343-9.
2009: Zinaida S Vexler; Midori A Yenari
Does inflammation after stroke affect the developing brain differently than adult brain?
Developmental neuroscience 2009;31(5):378-93.
2008: Michael F Wendland; Joel Faustino; Tim West; Catherine Manabat; David M Holtzman; Zinaida S Vexler
Early diffusion-weighted MRI as a predictor of caspase-3 activation after hypoxic-ischemic insult in neonatal rodents.
Stroke; a journal of cerebral circulation 2008;39(6):1862-8.
2007: Sheryl P Denker; Shaoquan Ji; Andra Dingman; Sarah Y Lee; nikita derugin; Michael F Wendland; Zinaida S Vexler
Macrophages are comprised of resident brain microglia not infiltrating peripheral monocytes acutely after neonatal stroke.
Journal of neurochemistry 2007;100(4):893-904.
2007: Fernando F Gonzalez; Patrick S McQuillen; Dezhi Mu; Yunsil Chang; Michael Wendland; Zinaida S Vexler; Donna M Ferriero
Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke.
Developmental neuroscience 2007;29(4-5):321-30.
2006: Zinaida S Vexler; Frank R Sharp; Giora Z Feuerstein; Stephen Ashwal; Marianne Thoresen; Jerome Y Yager; Donna M Ferriero
Translational stroke research in the developing brain.
Pediatric neurology 2006;34(6):459-63.
2006: Andra Dingman; Sarah Y Lee; nikita derugin; Michael F Wendland; Zinaida S Vexler
Aminoguanidine inhibits caspase-3 and calpain activation without affecting microglial activation following neonatal transient cerebral ischemia.
Journal of neurochemistry 2006;96(5):1467-79.
2006: Yasuhiko Matsumori; Frances J Northington; Shwuhuey M Hong; Takamasa Kayama; R Ann Sheldon; Zinaida S Vexler; Donna M Ferriero; Philip R Weinstein; Jialing Liu
Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice overexpressing Hsp70.
Stroke; a journal of cerebral circulation 2006;37(2):507-12.
2005: nikita derugin; Andra Dingman; Michael F Wendland; Christine Fox; Andrew Bollen; Zinaida S Vexler
Magnetic resonance imaging as a surrogate measure for histological sub-chronic endpoint in a neonatal rat stroke model.
Brain research 2005;1066(1-2):49-56.
2005: Dezhi Mu; Yun Sil Chang; Zinaida S Vexler; Donna M Ferriero
Hypoxia-inducible factor 1alpha and erythropoietin upregulation with deferoxamine salvage after neonatal stroke.
Experimental neurology 2005;195(2):407-15.
2005: Christine Fox; Andra Dingman; nikita derugin; Michael F Wendland; Catherine Manabat; Shaoquan Ji; Donna M Ferriero; Zinaida S Vexler
Minocycline confers early but transient protection in the immature brain following focal cerebral ischemia-reperfusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(9):1138-49.
2005: Midori A Yenari; Jialing Liu; Zhen Zheng; Zinaida S Vexler; Jong Eun Lee; Rona G Giffard
Antiapoptotic and anti-inflammatory mechanisms of heat-shock protein protection.
Annals of the New York Academy of Sciences 2005;1053():74-83.
2005: Yun Sil Chang; Dezhi Mu; Michael Wendland; R Ann Sheldon; Zinaida S Vexler; Patrick S McQuillen; Donna M Ferriero
Erythropoietin improves functional and histological outcome in neonatal stroke.
Pediatric research 2005;58(1):106-11.
2005: Yasuhiko Matsumori; Shwuhuey M Hong; Koji Aoyama; Yang Fan; Takamasa Kayama; R Ann Sheldon; Zinaida S Vexler; Donna M Ferriero; Philip R Weinstein; Jialing Liu
Hsp70 overexpression sequesters AIF and reduces neonatal hypoxic/ischemic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(7):899-910.
2004: Xiangning Jiang; Dezhi Mu; Catherine Manabat; Anita A Koshy; Stephan Christen; Martin G Täuber; Zinaida S Vexler; Donna M Ferriero
Differential vulnerability of immature murine neurons to oxygen-glucose deprivation.
Experimental neurology 2004;190(1):224-32.
2004: R Ann Sheldon; Xiangning Jiang; Carla Francisco; Stephan Christen; Zinaida S Vexler; Martin G Täuber; Donna M Ferriero
Manipulation of antioxidant pathways in neonatal murine brain.
Pediatric research 2004;56(4):656-62.
2003: Dezhi Mu; Xiangning Jiang; R Ann Sheldon; Christine K Fox; Shannon E G Hamrick; Zinaida S Vexler; Donna M Ferriero
Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model.
Neurobiology of disease 2003;14(3):524-34.
2003: Zinaida S Vexler; Arthur Wong; Carla Francisco; Catherine Manabat; Stephan Christen; Martin G Täuber; Donna M Ferriero; George A Gregory
Fructose-1,6-bisphosphate preserves intracellular glutathione and protects cortical neurons against oxidative stress.
Brain research 2003;960(1-2):90-8.
2003: Catherine Manabat; B H Han; Michael Wendland; nikita derugin; C K Fox; J Choi; David M Holtzman; Donna M Ferriero; Zinaida S Vexler
Reperfusion differentially induces caspase-3 activation in ischemic core and penumbra after stroke in immature brain.
Stroke; a journal of cerebral circulation 2003;34(1):207-13.
2002: Jack M Parent; Zinaida S Vexler; Chao Gong; nikita derugin; Donna M Ferriero
Rat forebrain neurogenesis and striatal neuron replacement after focal stroke.
Annals of neurology 2002;52(6):802-13.
2001: Paul H Donohoe; Christian S Fahlman; Philip E Bickler; Zinaida S Vexler; George A Gregory
Neuroprotection and intracellular Ca2+ modulation with fructose-1,6-bisphosphate during in vitro hypoxia-ischemia involves phospholipase C-dependent signaling.
Brain research 2001;917(2):158-66.
2001: Zinaida S Vexler; Donna M Ferriero
Molecular and biochemical mechanisms of perinatal brain injury.
Seminars in neonatology : SN 2001;6(2):99-108.
2000: nikita derugin; Michael Wendland; K Muramatsu; Timothy P L Roberts; G Gregory; Donna M Ferriero; Zinaida S Vexler
Evolution of brain injury after transient middle cerebral artery occlusion in neonatal rats.
Stroke; a journal of cerebral circulation 2000;31(7):1752-61.
1999: Zinaida S Vexler; M Berrios; Philip C Ursell; A Sola; Donna M Ferriero; George A Gregory
Toxicity of fructose-1,6-bisphosphate in developing normoxic rats.
Pharmacology & toxicology 1999;84(3):115-21.
1998: nikita derugin; Donna M Ferriero; Zinaida S Vexler
Neonatal reversible focal cerebral ischemia: a new model.
Neuroscience research 1998;32(4):349-53.
1997: Zinaida S Vexler; Timothy P L Roberts; A W Bollen; nikita derugin; Allen I Arieff
Transient cerebral ischemia. Association of apoptosis induction with hypoperfusion.
The Journal of clinical investigation 1997;99(6):1453-9.
1996: Zinaida S Vexler; Marc Symons; Diane L Barber
Activation of Na+-H+ exchange is necessary for RhoA-induced stress fiber formation.
The Journal of biological chemistry 1996;271(37):22281-4.
1996: Timothy P L Roberts; Zinaida S Vexler; V Vexler; nikita derugin; J Kucharczyk
Sensitivity of high-speed "perfusion-sensitive" magnetic resonance imaging to mild cerebral ischemia.
European radiology 1996;6(5):645-9.
1995: Timothy P L Roberts; Zinaida S Vexler; nikita derugin; E Kozniewska; J Kucharczyk; C J Emmett
Evaluation of recombinant human basic fibroblast growth factor (rhbFGF) as a cerebroprotective agent using high speed MR imaging.
Brain research 1995;699(1):51-61.
1995: A I Arieff; E Kozniewska; Timothy P L Roberts; Zinaida S Vexler; Juan Carlos Ayus; J Kucharczyk
Age, gender, and vasopressin affect survival and brain adaptation in rats with metabolic encephalopathy.
The American journal of physiology 1995;268(5 Pt 2):R1143-52.
1995: E Kozniewska; Timothy P L Roberts; Zinaida S Vexler; M Oseka; J Kucharczyk; A I Arieff
Hormonal dependence of the effects of metabolic encephalopathy on cerebral perfusion and oxygen utilization in the rat.
Circulation research 1995;76(4):551-8.
1994: Zinaida S Vexler; Juan Carlos Ayus; Timothy P L Roberts; C L Fraser; J Kucharczyk; A I Arieff
Hypoxic and ischemic hypoxia exacerbate brain injury associated with metabolic encephalopathy in laboratory animals.
The Journal of clinical investigation 1994;93(1):256-64.
1994: Zinaida S Vexler; Timothy P L Roberts; J Kucharczyk; A I Arieff
Severe brain edema associated with cumulative effects of hyponatremic encephalopathy and ischemic hypoxia.
Acta neurochirurgica. Supplementum 1994;60():246-9.
1994: Zinaida S Vexler; Timothy P L Roberts; nikita derugin; E Kozniewska; A I Arieff; J Kucharczyk
Mechanisms of brain injury associated with partial and complete occlusion of the MCA in cat.
Acta neurochirurgica. Supplementum 1994;60():211-5.
1993: Timothy P L Roberts; Zinaida S Vexler; nikita derugin; M E Moseley; J Kucharczyk
High-speed MR imaging of ischemic brain injury following stenosis of the middle cerebral artery.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(6):940-6.
1993: J Kucharczyk; Zinaida S Vexler; Timothy P L Roberts; H S Asgari; J Mintorovitch; nikita derugin; A D Watson; M E Moseley
Echo-planar perfusion-sensitive MR imaging of acute cerebral ischemia.
Radiology 1993;188(3):711-7.
1993: A J de Crespigny; Michael F Wendland; nikita derugin; Zinaida S Vexler; M E Moseley
Rapid MR imaging of a vascular challenge to focal ischemia in cat brain.
Journal of magnetic resonance imaging : JMRI 1993;3(3):475-81.
1993: J Kucharczyk; H Asgari; J Mintorovitch; Zinaida S Vexler; S Rocklage; A Watson; M Moseley
Cerebrovascular transit characteristics of DyDTPA-BMA and GdDTPA-BMA on normal and ischemic cat brain.
AJNR. American journal of neuroradiology 1993;14(2):289-96.
1991: M E Moseley; Zinaida S Vexler; H S Asgari; J Mintorovitch; nikita derugin; S Rocklage; J Kucharczyk
Comparison of Gd- and Dy-chelates for T2 contrast-enhanced imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;22(2):259-64; discussion 265-7.
1991: J Kucharczyk; H Asgari; J Mintorovitch; Zinaida S Vexler; M Moseley; A Watson; S Rocklage
Magnetic resonance imaging of brain perfusion using the nonionic contrast agents Dy-DTPA-BMA and Gd-DTPA-BMA.
Investigative radiology 1991;26 Suppl 1():S250-2; discussion S253-4.