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Thomas Victor

Research Profile

Living Beings

Mycobacterium tuberculosis

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South Africa

Chemicals & Drugs

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Publications

TOP 3
M de Vos; Sebastien Gagneux; B Müller; Paul D van Helden; P A Black; S Borrell; Robin M Warren; Thomas C Victor
Putative compensatory mutations in the rpoC gene of rifampin-resistant Mycobacterium tuberculosis are associated with ongoing transmission.
Frik A Sirgel; Erik C Böttger; Marisa Klopper; Thomas C Victor; Robin M Warren; Paul D van Helden
The rationale for using rifabutin in the treatment of MDR and XDR tuberculosis outbreaks.
James A Seddon; Thomas C Victor; Annemarie M Jordaan; H Simon Schaaf
Discordant drug susceptibility for mycobacterium tuberculosis within families.

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All Publications

2013: M de Vos; Sebastien Gagneux; B Müller; Paul D van Helden; P A Black; S Borrell; Robin M Warren; Thomas C Victor
Putative compensatory mutations in the rpoC gene of rifampin-resistant Mycobacterium tuberculosis are associated with ongoing transmission.
Antimicrobial agents and chemotherapy 2013;57(2):827-32.
2013: Frik A Sirgel; Erik C Böttger; Marisa Klopper; Thomas C Victor; Robin M Warren; Paul D van Helden
The rationale for using rifabutin in the treatment of MDR and XDR tuberculosis outbreaks.
PloS one 2013;8(3):e59414.
2012: James A Seddon; Thomas C Victor; Annemarie M Jordaan; H Simon Schaaf
Discordant drug susceptibility for mycobacterium tuberculosis within families.
The Pediatric infectious disease journal 2012;31(7):783-5.
2012: Elizabeth M Streicher; Marisa Tait; Andre Trollip; Paul D van Helden; Thomas C Victor; Violet Chihota; Nicolaas C Gey van Pittius; Kim G P Hoek; Charmaine Mlambo; Borna Müller; Manormoney Pillay; Frik A Sirgel; Robin M Warren
Emergence and treatment of multidrug resistant (MDR) and extensively drug-resistant (XDR) tuberculosis in South Africa.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2012;12(4):686-94.
2012: Frik A Sirgel; Elizabeth M Streicher; Paul D van Helden; Thomas C Victor; Robin M Warren; Erik C Böttger
gyrA mutations and phenotypic susceptibility levels to ofloxacin and moxifloxacin in clinical isolates of Mycobacterium tuberculosis.
The Journal of antimicrobial chemotherapy 2012;67(5):1088-93.
2012: E M Streicher; Paul D van Helden; Thomas C Victor; R M Anthony; I Bergval; M Bosman; E C Böttger; G Coetzee; K Dheda; N C Gey van Pittius; Robin M Warren
Mycobacterium tuberculosis population structure determines the outcome of genetics-based second-line drug resistance testing.
Antimicrobial agents and chemotherapy 2012;56(5):2420-7.
2012: Frik A Sirgel; Elizabeth M Streicher; Paul D van Helden; Thomas C Victor; Robin M Warren; Erik C Böttger
embB306 mutations as molecular indicators to predict ethambutol susceptibility in Mycobacterium tuberculosis.
Chemotherapy 2012;58(5):358-63.
2011: M Hanekom; C R E McEvoy; Paul D van Helden; Thomas C Victor; Nicolaas C Gey van Pittius; Robin M Warren
Mycobacterium tuberculosis Beijing genotype: a template for success.
Tuberculosis (Edinburgh, Scotland) 2011;91(6):510-23.
2011: Kim G P Hoek; Paul D van Helden; Annelies van Rie; Robin M Warren; Thomas C Victor
Detecting drug-resistant tuberculosis: the importance of rapid testing.
Molecular diagnosis & therapy 2011;15(4):189-94.
2011: Gail E Louw; C R E McEvoy; Megan Murray; Paul D van Helden; Nicolaas C Gey van Pittius; Melanie Grobbelaar; Rogelio Hernandez-Pando; Adelina Jimenez; Rosalba Leon; Robin M Warren; Thomas C Victor
Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux.
American journal of respiratory and critical care medicine 2011;184(2):269-76.
2011: Novel N Chegou; Kim G P Hoek; Magdalena Kriel; Robin M Warren; Thomas C Victor; Gerhard Walzl
Tuberculosis assays: past, present and future.
Expert review of anti-infective therapy 2011;9(4):457-69.
2011: B Müller; Elizabeth M Streicher; K G P Hoek; M Tait; A Trollip; M Bosman; G J Coetzee; E M Chabula-Nxiweni; E Hoosain; Nicolaas C Gey van Pittius; Thomas C Victor; Paul D van Helden; Robin M Warren
inhA promoter mutations: a gateway to extensively drug-resistant tuberculosis in South Africa?
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2011;15(3):344-51.
2010: Anneke C Hesseling; Ben J Marais; H Lester Kirchner; Anna Maria Mandalakas; W Brittle; Thomas C Victor; Robin M Warren; H Simon Schaaf
Mycobacterial genotype is associated with disease phenotype in children.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2010;14(10):1252-8.
2010: R Johnson; Robin M Warren; Gian D van der Spuy; Nicolaas C Gey van Pittius; D Theron; Elizabeth M Streicher; M Bosman; G J Coetzee; Paul D van Helden; Thomas C Victor
Drug-resistant tuberculosis epidemic in the Western Cape driven by a virulent Beijing genotype strain.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2010;14(1):119-21.
2009: H Simon Schaaf; Thomas C Victor; A Venter; W Brittle; Annemarie M Jordaan; Anneke C Hesseling; Ben J Marais; Paul D van Helden; Peter R Donald
Ethionamide cross- and co-resistance in children with isoniazid-resistant tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2009;13(11):1355-9.
2009: G E Louw; Robin M Warren; N C Gey van Pittius; C R E McEvoy; Paul D van Helden; Thomas C Victor
A balancing act: efflux/influx in mycobacterial drug resistance.
Antimicrobial agents and chemotherapy 2009;53(8):3181-9.
2009: Robin M Warren; Elizabeth M Streicher; N C Gey van Pittius; Ben J Marais; Gian D van der Spuy; Thomas C Victor; Frik A Sirgel; Peter R Donald; Paul D van Helden
The clinical relevance of Mycobacterial pharmacogenetics.
Tuberculosis (Edinburgh, Scotland) 2009;89(3):199-202.
2009: Pieter Uys; Robin Warren; Paul D van Helden; Megan Murray; Thomas C Victor
Potential of rapid diagnosis for controlling drug-susceptible and drug-resistant tuberculosis in communities where Mycobacterium tuberculosis infections are highly prevalent.
Journal of clinical microbiology 2009;47(5):1484-90.
2008: M Hanekom; Gian D van der Spuy; Nicolaas C Gey van Pittius; C R E McEvoy; K G P Hoek; S L Ndabambi; Annemarie M Jordaan; Thomas C Victor; Paul D van Helden; Robin M Warren
Discordance between mycobacterial interspersed repetitive-unit-variable-number tandem-repeat typing and IS6110 restriction fragment length polymorphism genotyping for analysis of Mycobacterium tuberculosis Beijing strains in a setting of high incidence of tuberculosis.
Journal of clinical microbiology 2008;46(10):3338-45.
2008: K G P Hoek; Nicolaas C Gey van Pittius; H Moolman-Smook; K Carelse-Tofa; Annemarie M Jordaan; Gian D van der Spuy; Elizabeth M Streicher; Thomas C Victor; Paul D van Helden; Robin M Warren
Fluorometric assay for testing rifampin susceptibility of Mycobacterium tuberculosis complex.
Journal of clinical microbiology 2008;46(4):1369-73.
2008: O J Strauss; Robin M Warren; Annemarie M Jordaan; Elizabeth M Streicher; M Hanekom; A A Falmer; H Albert; A Trollip; E Hoosain; Paul D van Helden; Thomas C Victor
Spread of a low-fitness drug-resistant Mycobacterium tuberculosis strain in a setting of high human immunodeficiency virus prevalence.
Journal of clinical microbiology 2008;46(4):1514-6.
2008: Rabia Johnson; Annemarie M Jordaan; Rob Warren; M Bosman; Douglas Young; Judit N Nagy; John R Wain; Paul D van Helden; Thomas C Victor
Drug susceptibility testing using molecular techniques can enhance tuberculosis diagnosis.
Journal of infection in developing countries 2008;2(1):40-5.
2007: Heidi Albert; Andre P Trollip; T Seaman; Celeste Abrahams; Richard J Mole; A Jordaan; Thomas C Victor; E Hoosain
Evaluation of a rapid screening test for rifampicin resistance in re-treatment tuberculosis patients in the Eastern Cape.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2007;97(9):858-63.
2007: C R E McEvoy; Alecia A Falmer; Nicolaas C Gey van Pittius; Thomas C Victor; Paul D van Helden; Robin M Warren
The role of IS6110 in the evolution of Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2007;87(5):393-404.
2007: M Hanekom; Gian D van der Spuy; Nicolaas C Gey van Pittius; C R E McEvoy; S L Ndabambi; Thomas C Victor; Eileen G Hoal; Paul D van Helden; Robin M Warren
Evidence that the spread of Mycobacterium tuberculosis strains with the Beijing genotype is human population dependent.
Journal of clinical microbiology 2007;45(7):2263-6.
2007: M Hanekom; Gian D van der Spuy; Elizabeth M Streicher; S L Ndabambi; C R E McEvoy; M Kidd; Nulda Beyers; Thomas C Victor; Paul D van Helden; Robin M Warren
A recently evolved sublineage of the Mycobacterium tuberculosis Beijing strain family is associated with an increased ability to spread and cause disease.
Journal of clinical microbiology 2007;45(5):1483-90.
2007: Violet Chihota; LM Apers; S Mungofa; Webster Kasongo; I M Nyoni; Ruth Tembwe; G M K Mbulo; M Tembo; Elizabeth M Streicher; Gian D van der Spuy; Thomas C Victor; Paul van Helden; Robin M Warren
Predominance of a single genotype of Mycobacterium tuberculosis in regions of Southern Africa.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2007;11(3):311-8.
2007: H S Schaaf; Thomas C Victor; Erica Engelke; W Brittle; Ben J Marais; Anneke C Hesseling; Paul D van Helden; Peter R Donald
Minimal inhibitory concentration of isoniazid in isoniazid-resistant Mycobacterium tuberculosis isolates from children.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2007;26(3):203-5.
2007: Thomas C Victor; Elizabeth M Streicher; C Kewley; Annemarie M Jordaan; Gian D van der Spuy; M Bosman; H Louw; M Murray; D Young; Paul D van Helden; Robin M Warren
Spread of an emerging Mycobacterium tuberculosis drug-resistant strain in the western Cape of South Africa.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2007;11(2):195-201.
2007: Elizabeth M Streicher; Thomas C Victor; Gian D van der Spuy; C Sola; N Rastogi; Paul D van Helden; Robin M Warren
Spoligotype signatures in the Mycobacterium tuberculosis complex.
Journal of clinical microbiology 2007;45(1):237-40.
2006: R Johnson; Robin Warren; O J Strauss; Annemarie M Jordaan; A A Falmer; Nulda Beyers; H Simon Schaaf; M Murray; K Cloete; Paul D van Helden; Thomas C Victor
An outbreak of drug-resistant tuberculosis caused by a Beijing strain in the western Cape, South Africa.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2006;10(12):1412-4.
2006: Paul D van Helden; Peter R Donald; Thomas C Victor; H Simon Schaaf; Eileen G Hoal; Gerhard Walzl; Robin M Warren
Antimicrobial resistance in tuberculosis: an international perspective.
Expert review of anti-infective therapy 2006;4(5):759-66.
2006: Ben J Marais; Thomas C Victor; Anneke C Hesseling; Madeleine Barnard; Annemarie M Jordaan; Wendy Brittle; Helmuth Reuter; Nulda Beyers; Paul D van Helden; Robin M Warren; H Simon Schaaf
Beijing and Haarlem genotypes are overrepresented among children with drug-resistant tuberculosis in the Western Cape Province of South Africa.
Journal of clinical microbiology 2006;44(10):3539-43.
2006: Rabia Johnson; Elizabeth M Streicher; Gail E Louw; Robin M Warren; Paul D van Helden; Thomas C Victor
Drug resistance in Mycobacterium tuberculosis.
Current issues in molecular biology 2006;8(2):97-111.
2006: Robin M Warren; Nicolaas C Gey van Pittius; M Barnard; Anneke C Hesseling; Erica Engelke; Marianna de Kock; M Cristina Gutierrez; G K Chege; Thomas C Victor; Eileen G Hoal; Paul D van Helden
Differentiation of Mycobacterium tuberculosis complex by PCR amplification of genomic regions of difference.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2006;10(7):818-22.
2006: G E Louw; Robin M Warren; P R Donald; M B Murray; M Bosman; Paul D van Helden; D B Young; Thomas C Victor
Frequency and implications of pyrazinamide resistance in managing previously treated tuberculosis patients.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2006;10(7):802-7.
2006: R Johnson; Annemarie M Jordaan; L Pretorius; Erica Engelke; Gian D van der Spuy; C Kewley; M Bosman; Paul D van Helden; Robin Warren; Thomas C Victor
Ethambutol resistance testing by mutation detection.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2006;10(1):68-73.
2006: Robin Warren; Marianna de Kock; Erica Engelke; Roseline Myburgh; Nicolaas C Gey van Pittius; Thomas C Victor; Paul van Helden
Safe Mycobacterium tuberculosis DNA extraction method that does not compromise integrity.
Journal of clinical microbiology 2006;44(1):254-6.
2005: Carolyn Sholto-Douglas-Vernon; Sandy James; Thomas C Victor; Edith Sim; Paul Dvan Helden
Mutational and expression analysis of tbnat and its response to isoniazid.
Journal of medical microbiology 2005;54(Pt 12):1189-97.
2005: Annelies van Rie; Thomas C Victor; Madalene Richardson; Rabia Johnson; Gian D van der Spuy; Emma J Murray; Nulda Beyers; Nicolaas C Gey van Pittius; Paul D van Helden; Robin M Warren
Reinfection and mixed infection cause changing Mycobacterium tuberculosis drug-resistance patterns.
American journal of respiratory and critical care medicine 2005;172(5):636-42.
2004: Eileen G Hoal; L A Lewis; Sarra E Jamieson; F Tanzer; Manda Rossouw; Thomas C Victor; R Hillerman; Nulda Beyers; Jenefer M Blackwell; Paul D van Helden
SLC11A1 (NRAMP1) but not SLC11A2 (NRAMP2) polymorphisms are associated with susceptibility to tuberculosis in a high-incidence community in South Africa.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2004;8(12):1464-71.
2004: Robin M Warren; Thomas C Victor; Elizabeth M Streicher; Madalene Richardson; Gian D van der Spuy; R Johnson; Violet Chihota; C Locht; Philip Supply; Paul D van Helden
Clonal expansion of a globally disseminated lineage of Mycobacterium tuberculosis with low IS6110 copy numbers.
Journal of clinical microbiology 2004;42(12):5774-82.
2004: Igor Mokrousov; N Vijaya Bhanu; Philip N Suffys; Gururaj Kadival; Sook Fan Yap; Sang-Nae Cho; Annemarie M Jordaan; Olga Narvskaya; Urvashi Balbir Singh; Harrison M Gomes; Hyeyoung Lee; Savita P Kulkarni; Kuo-Chieh Lim; Baldip K Khan; Dick Van Soolingen; Thomas C Victor; Leo M Schouls
Multicenter evaluation of reverse line blot assay for detection of drug resistance in Mycobacterium tuberculosis clinical isolates.
Journal of microbiological methods 2004;57(3):323-35.
2004: Anneke C Hesseling; H Simon Schaaf; Thomas C Victor; Nulda Beyers; Ben J Marais; Mark F Cotton; Ian Wiid; Robert P Gie; Paul van Helden; Robin M Warren
Resistant Mycobacterium bovis Bacillus Calmette-Guérin disease: implications for management of Bacillus Calmette-Guérin Disease in human immunodeficiency virus-infected children.
The Pediatric infectious disease journal 2004;23(5):476-9.
2004: Willie Githui; Annemarie M Jordaan; Ernest Juma; P Kinyanjui; FG Karimi; J Kimwomi; HK Meme; P Mumbi; Elizabeth M Streicher; Robin Warren; Paul D van Helden; Thomas C Victor
Identification of MDR-TB Beijing/W and other Mycobacterium tuberculosis genotypes in Nairobi, Kenya.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2004;8(3):352-60.
2004: Robin M Warren; Thomas C Victor; Elizabeth M Streicher; Madalene Richardson; Nulda Beyers; Nicolaas C Gey van Pittius; Paul D van Helden
Patients with active tuberculosis often have different strains in the same sputum specimen.
American journal of respiratory and critical care medicine 2004;169(5):610-4.
2004: Elizabeth M Streicher; Robin M Warren; C Kewley; J Simpson; N Rastogi; C Sola; Gian D van der Spuy; Paul D van Helden; Thomas C Victor
Genotypic and phenotypic characterization of drug-resistant Mycobacterium tuberculosis isolates from rural districts of the Western Cape Province of South Africa.
Journal of clinical microbiology 2004;42(2):891-4.
2004: Thomas C Victor; Petra E W De Haas; Annemarie M Jordaan; Gian D van der Spuy; Madalene Richardson; Dick Van Soolingen; Paul D van Helden; Robin Warren
Molecular characteristics and global spread of Mycobacterium tuberculosis with a western cape F11 genotype.
Journal of clinical microbiology 2004;42(2):769-72.
2003: Desiré Barnard; Karen Lehmann; Eileen G Hoal; Paul D van Helden; Thomas C Victor
The spectrum of mutations in TP53 in laryngeal cancer patients from a high-incidence population shows similarities to many of the known mutational hotspots.
Cancer genetics and cytogenetics 2003;145(2):126-32.
2003: S L Sampson; Robin M Warren; Madalene Richardson; Thomas C Victor; Annemarie M Jordaan; Gian D van der Spuy; Paul D van Helden
IS6110-mediated deletion polymorphism in the direct repeat region of clinical isolates of Mycobacterium tuberculosis.
Journal of bacteriology 2003;185(9):2856-66.
2003: Craig H Adams; Cedric J Werely; Thomas C Victor; Eileen G Hoal; Gawie Rossouw; Paul D van Helden
Allele frequencies for glutathione S-transferase and N-acetyltransferase 2 differ in African population groups and may be associated with oesophageal cancer or tuberculosis incidence.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003;41(4):600-5.
2003: Marelette Vos; Craig H Adams; Thomas C Victor; Paul D van Helden
Polymorphisms and mutations found in the regions flanking exons 5 to 8 of the TP53 gene in a population at high risk for esophageal cancer in South Africa.
Cancer genetics and cytogenetics 2003;140(1):23-30.
2002: Robin M Warren; Elizabeth M Streicher; S L Sampson; Gian D van der Spuy; Madalene Richardson; D Nguyen; MA Behr; Thomas C Victor; Paul D van Helden
Microevolution of the direct repeat region of Mycobacterium tuberculosis: implications for interpretation of spoligotyping data.
Journal of clinical microbiology 2002;40(12):4457-65.
2002: Robin M Warren; Elizabeth M Streicher; Salome Charalambous; Gavin Churchyard; Gian D van der Spuy; A D Grant; Paul D van Helden; Thomas C Victor
Use of spoligotyping for accurate classification of recurrent tuberculosis.
Journal of clinical microbiology 2002;40(10):3851-3.
2002: Thomas C Victor; Hyeyoung Lee; Sang-Nae Cho; Annemarie M Jordaan; Gian D van der Spuy; Paul D van Helden; Robin Warren
Molecular detection of early appearance of drug resistance during Mycobacterium tuberculosis infection.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2002;40(9):876-81.
2002: Miguel Viveiros; Isabel Portugal; Rosário Bettencourt; Thomas C Victor; Annemarie M Jordaan; Clara Leandro; Diane Ordway; Leonard Amaral
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2002;46(9):2804-10.
2002: Thomas C Victor; Paul D van Helden; Robin Warren
Prediction of drug resistance in M. tuberculosis: molecular mechanisms, tools, and applications.
IUBMB life 2002;53(4-5):231-7.
2002: Paul D van Helden; Robin M Warren; Thomas C Victor; Gian D van der Spuy; Madalene Richardson; Eileen Hoal-van Helden
Strain families of Mycobacterium tuberculosis.
Trends in microbiology 2002;10(4):167-8; author reply 168.
2001: Thomas C Victor; Annelies van Rie; Annemarie M Jordaan; Madalene Richardson; Gian D van der Spuy; Nulda Beyers; Paul D van Helden; Robin Warren
Sequence polymorphism in the rrs gene of Mycobacterium tuberculosis is deeply rooted within an evolutionary clade and is not associated with streptomycin resistance.
Journal of clinical microbiology 2001;39(11):4184-6.
2001: Anna M Upton; Adeel Mushtaq; Thomas C Victor; S L Sampson; Sandy James; D M Smith; P V van Helden; Edith Sim
Arylamine N-acetyltransferase of Mycobacterium tuberculosis is a polymorphic enzyme and a site of isoniazid metabolism.
Molecular microbiology 2001;42(2):309-17.
2001: Annelies van Rie; Robin Warren; I Mshanga; Annemarie M Jordaan; Gian D van der Spuy; Madalene Richardson; J Simpson; Robert P Gie; D A Enarson; Nulda Beyers; Paul D van Helden; Thomas C Victor
Analysis for a limited number of gene codons can predict drug resistance of Mycobacterium tuberculosis in a high-incidence community.
Journal of clinical microbiology 2001;39(2):636-41.
2000: Robin M Warren; S L Sampson; Madalene Richardson; Gian D van der Spuy; Carl Lombard; Thomas C Victor; Paul D van Helden
Mapping of IS6110 flanking regions in clinical isolates of Mycobacterium tuberculosis demonstrates genome plasticity.
Molecular microbiology 2000;37(6):1405-16.
2000: H Simon Schaaf; Annelies van Rie; Robert P Gie; Nulda Beyers; Thomas C Victor; Paul D van Helden; Peter R Donald
Transmission of multidrug-resistant tuberculosis.
The Pediatric infectious disease journal 2000;19(8):695-9.
1999: Annelies van Rie; Robin M Warren; Nulda Beyers; Robert P Gie; C N Classen; M Richardson; S L Sampson; Thomas C Victor; Paul D van Helden
Transmission of a multidrug-resistant Mycobacterium tuberculosis strain resembling "strain W" among noninstitutionalized, human immunodeficiency virus-seronegative patients.
The Journal of infectious diseases 1999;180(5):1608-15.
1999: Annelies van Rie; Robin Warren; Madalene Richardson; Thomas C Victor; Robert P Gie; D A Enarson; Nulda Beyers; Paul D van Helden
Exogenous reinfection as a cause of recurrent tuberculosis after curative treatment.
The New England journal of medicine 1999;341(16):1174-9.
1999: Robin Warren; M Richardson; Gian D van der Spuy; Thomas C Victor; S Sampson; Nulda Beyers; Paul van Helden
DNA fingerprinting and molecular epidemiology of tuberculosis: use and interpretation in an epidemic setting.
Electrophoresis 1999;20(8):1807-12.
1999: Eileen Hoal-van Helden; J Epstein; Thomas C Victor; D Hon; L A Lewis; Nulda Beyers; D Zurakowski; A B Ezekowitz; Paul D van Helden
Mannose-binding protein B allele confers protection against tuberculous meningitis.
Pediatric research 1999;45(4 Pt 1):459-64.
1999: Thomas C Victor; Annemarie M Jordaan; Annelies van Rie; Gian D van der Spuy; Madalene Richardson; Paul D van Helden; Robin Warren
Detection of mutations in drug resistance genes of Mycobacterium tuberculosis by a dot-blot hybridization strategy.
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1999;79(6):343-8.
1997: Thomas C Victor; R Warren; J L Butt; Annemarie M Jordaan; J V Felix; A Venter; Frik A Sirgel; H Simon Schaaf; Peter R Donald; M Richardson; Michael Cynamon; Paul D van Helden
Genome and MIC stability in Mycobacterium tuberculosis and indications for continuation of use of isoniazid in multidrug-resistant tuberculosis.
Journal of medical microbiology 1997;46(10):847-57.
1997: Thomas C Victor; Robin Warren; Nulda Beyers; P D van Helden
Transmission of multidrug-resistant strains of Mycobacterium tuberculosis in a high incidence community.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1997;16(7):548-9.
1997: JL Doran; Y Pang; K E Mdluli; AJ Moran; Thomas C Victor; R W Stokes; E Mahenthiralingam; B N Kreiswirth; J L Butt; GS Baron; JD Treit; V J Kerr; P D Van Helden; M C Roberts; Francis E Nano
Mycobacterium tuberculosis efpA encodes an efflux protein of the QacA transporter family.
Clinical and diagnostic laboratory immunology 1997;4(1):23-32.
1996: Thomas C Victor; G S Pretorius; J V Felix; Annemarie M Jordaan; P D van Helden; K D Eisenach
katG mutations in isoniazid-resistant strains of Mycobacterium tuberculosis are not infrequent.
Antimicrobial agents and chemotherapy 1996;40(6):1572.
1996: Thomas C Victor; Annemarie M Jordaan; E J Van Schalkwyk; G J Coetzee; P D Van Helden
Strain-specific variation in the dnaJ gene of mycobacteria.
Journal of medical microbiology 1996;44(5):332-9.
1996: L A Lewis; Thomas C Victor; E G Helden; J M Blackwell; F da Silva-Tatley; S Tullett; M Ehlers; Nulda Beyers; Peter R Donald; P D van Helden
Identification of C to T mutation at position -236 bp in the human NRAMP1 gene promoter.
Immunogenetics 1996;44(4):309-11.
1996: G S Pretorius; Frik A Sirgel; H Simon Schaaf; P D van Helden; Thomas C Victor
Rifampicin resistance in Mycobacterium tuberculosis--rapid detection and implications in chemotherapy.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1996;86(1):50-5.
1995: G S Pretorius; P D van Helden; Frik A Sirgel; K D Eisenach; Thomas C Victor
Mutations in katG gene sequences in isoniazid-resistant clinical isolates of Mycobacterium tuberculosis are rare.
Antimicrobial agents and chemotherapy 1995;39(10):2276-81.
1995: Johann W Schneider; H Francois Jordaan; D H Geiger; Thomas C Victor; P D Van Helden; D J Rossouw
Erythema induratum of Bazin. A clinicopathological study of 20 cases and detection of Mycobacterium tuberculosis DNA in skin lesions by polymerase chain reaction.
The American Journal of dermatopathology 1995;17(4):350-6.
1994: E H Lombard; Thomas C Victor; Annemarie M Jordaan; P D van Helden
The detection of Mycobacterium tuberculosis in bone marrow aspirate using the polymerase chain reaction.
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1994;75(1):65-9.
1994: R Winterbach; P D Van Helden; J Janse van Rensburg; Thomas C Victor
Incidence of heat-labile enterotoxin-producing Escherichia coli detected by means of polymerase chain reaction amplification.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1994;84(2):85-7.
1993: Johann W Schneider; D H Geiger; D J Rossouw; H Francois Jordaan; Thomas C Victor; P D van Helden
Mycobacterium tuberculosis DNA in erythema induratum of Bazin.
Lancet 1993;342(8873):747-8.
1993: Thomas C Victor; Annemarie M Jordaan; R du Toit; P D Van Helden
Laboratory experience and guidelines for avoiding false positive polymerase chain reaction results.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1993;31(8):531-5.
1993: R du Toit; Thomas C Victor; P D van Helden
Empirical evaluation of conditions influencing the polymerase chain reaction: enterotoxigenic Escherichia coli as a test case.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1993;31(4):225-31.
1993: Peter R Donald; Thomas C Victor; Annemarie M Jordaan; Johan F Schoeman; P D van Helden
Polymerase chain reaction in the diagnosis of tuberculous meningitis.
Scandinavian journal of infectious diseases 1993;25(5):613-7.
1992: Thomas C Victor; H Francois Jordaan; D J Van Niekerk; M Louw; Annemarie M Jordaan; P D Van Helden
Papulonecrotic tuberculid. Identification of Mycobacterium tuberculosis DNA by polymerase chain reaction.
The American Journal of dermatopathology 1992;14(6):491-5.
1992: Thomas C Victor; R du Toit; P D van Helden
Purification of sputum samples through sucrose improves detection of Mycobacterium tuberculosis by polymerase chain reaction.
Journal of clinical microbiology 1992;30(6):1514-7.
1991: P D du van Helden; R Toit; Annemarie M Jordaan; B Taljaard; J Pitout; Thomas C Victor
The use of the polymerase chain reaction test in the diagnosis of tuberculosis.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1991;80(10):515-6.
1991: Thomas C Victor; R du Toit; J van Zyl; A J Bester; P D van Helden
Improved method for the routine identification of toxigenic Escherichia coli by DNA amplification of a conserved region of the heat-labile toxin A subunit.
Journal of clinical microbiology 1991;29(1):158-61.
1990: Thomas C Victor; R Du Toit; Annemarie M Jordaan; A J Bester; P D van Helden
No evidence for point mutations in codons 12, 13, and 61 of the ras gene in a high-incidence area for esophageal and gastric cancers.
Cancer research 1990;50(16):4911-4.