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Andrew Boyd

Research Profile

Chemicals & Drugs

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Mouse

Physiology

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Publications

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Bryan W Day; Jennifer K Ellacott; Kathleen S Ensbey; Angus Harding; Po Inglis; Paul R Jamieson; Kum Kum Khanna; Martin Lackmann; Lucie Leveque; Jason D Lickliter; Yi Chieh Lim; Carolin Offenhäuser; Geoffrey Osborne; Brent A Reynolds; Brett W Stringer; Michael J Ting; David G Walker; John Wilson; Fares Al-Ejeh; Suzanne Allan; Zara C Bruce; Sara Charmsaz; Leanne T Cooper; Andrew W Boyd
EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme.
Nirmitha I Herath; Celio Pouponnot; Fiona M Smith; Mark Spanevello; James D Doecke; Andrew W Boyd
Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis.
Bryan W Day; Vicky J Ellis; Kathleen S Ensbey; Po L Inglis; Paul R Jamieson; Jason D Lickliter; Brent A Reynolds; Mark D Spanevello; Brett W Stringer; David G Walker; Christopher L Brown; Jacinta C Carter; Sara Charmsaz; Joanne M Cox; Suzanne Allan; Andrew W Boyd
ELK4 neutralization sensitizes glioblastoma to apoptosis through downregulation of the anti-apoptotic protein Mcl-1.

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All Publications

2013: Bryan W Day; Jennifer K Ellacott; Kathleen S Ensbey; Angus Harding; Po Inglis; Paul R Jamieson; Kum Kum Khanna; Martin Lackmann; Lucie Leveque; Jason D Lickliter; Yi Chieh Lim; Carolin Offenhäuser; Geoffrey Osborne; Brent A Reynolds; Brett W Stringer; Michael J Ting; David G Walker; John Wilson; Fares Al-Ejeh; Suzanne Allan; Zara C Bruce; Sara Charmsaz; Leanne T Cooper; Andrew W Boyd
EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme.
Cancer cell 2013;23(2):238-48.
2012: Nirmitha I Herath; Celio Pouponnot; Fiona M Smith; Mark Spanevello; James D Doecke; Andrew W Boyd
Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis.
European journal of cancer (Oxford, England : 1990) 2012;48(5):753-62.
2011: Bryan W Day; Vicky J Ellis; Kathleen S Ensbey; Po L Inglis; Paul R Jamieson; Jason D Lickliter; Brent A Reynolds; Mark D Spanevello; Brett W Stringer; David G Walker; Christopher L Brown; Jacinta C Carter; Sara Charmsaz; Joanne M Cox; Suzanne Allan; Andrew W Boyd
ELK4 neutralization sensitizes glioblastoma to apoptosis through downregulation of the anti-apoptotic protein Mcl-1.
Neuro-oncology 2011;13(11):1202-12.
2011: Elham Sadeqzadeh; Naomi M Scott; Kristy L Shipman; Chaojun Song; Andrew W Boyd; Gordon F Burns; Charles E de Bock; Peter Hersey; Boquan Jin; Camila S Oliveira; Trina Yeadon; Xu Dong Zhang; Rick F Thorne
Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products.
The Journal of biological chemistry 2011;286(32):28181-91.
2010: Rick F Thorne; Kylie J Ralston; Charles Edo de Bock; Nizar M Mhaidat; Xu Dong Zhang; Andrew W Boyd; Gordon F Burns
Palmitoylation of CD36/FAT regulates the rate of its post-transcriptional processing in the endoplasmic reticulum.
Biochimica et biophysica acta 2010;1803(11):1298-307.
2010: Nirmitha I Herath; Andrew W Boyd
The role of Eph receptors and ephrin ligands in colorectal cancer.
International journal of cancer. Journal international du cancer 2010;126(9):2003-11.
2010: Jennifer K McCarron; Brett W Stringer; Bryan W Day; Andrew W Boyd
Ephrin expression and function in cancer.
Future oncology (London, England) 2010;6(1):165-76.
2009: Nirmitha I Herath; J Doecke; M D Spanevello; Barbara A Leggett; Andrew W Boyd
Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival.
British journal of cancer 2009;100(7):1095-102.
2008: Sabine H Wimmer-Kleikamp; Eva Nievergall; Kristina Gegenbauer; Samantha Adikari; Mariam Mansour; Trina Yeadon; Andrew W Boyd; Neill R Patani; Martin Lackmann
Elevated protein tyrosine phosphatase activity provokes Eph/ephrin-facilitated adhesion of pre-B leukemia cells.
Blood 2008;112(3):721-32.
2008: Martin Lackmann; Andrew W Boyd
Eph, a protein family coming of age: more confusion, insight, or complexity?
Science signaling 2008;1(15):re2.
2006: Andreas Hüttmann; Ulrich Dührsen; Katja Heydarian; Ludger Klein-Hitpass; Tanja Boes; Andrew W Boyd; Chung-Leung Li
Gene expression profiles in murine hematopoietic stem cells revisited: analysis of cDNA libraries reveals high levels of translational and metabolic activities.
Stem cells (Dayton, Ohio) 2006;24(7):1719-27.
2006: Nirmitha I Herath; Mark Spanevello; Sabe Sabesan; Tanya Newton; Margaret Cummings; Shannon Duffy; Douglas Lincoln; Glen Boyle; Peter G Parsons; Andrew W Boyd
Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival.
BMC cancer 2006;6():144.
2006: Bryan W Day; Fiona M Smith; Ke Chen; Jennifer K McCarron; Nirmitha I Herath; Martin Lackmann; Andrew W Boyd
Eph/Ephrin membrane proteins: a mammalian expression vector pTIg-BOS-Fc allowing rapid protein purification.
Protein and peptide letters 2006;13(2):193-6.
2005: Christopher Vearing; Fook-Thean Lee; Sabine H Wimmer-Kleikamp; Violeta Spirkoska; Catherine To; Con Stylianou; Mark Spanevello; Martin W Brechbiel; Andrew W Boyd; Andrew M Scott; Martin Lackmann
Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: potential as EphA3-specific tumor-targeting reagents.
Cancer research 2005;65(15):6745-54.
2005: Bryan Day; Catherine To; Juha P Himanen; Fiona M Smith; Dimitar B Nikolov; Andrew W Boyd; Martin Lackmann
Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.
The Journal of biological chemistry 2005;280(28):26526-32.
2005: Michelle Down; Maryanne Power; Shirley I Smith; Kylie Ralston; Mark Spanevello; Gordon F Burns; Andrew W Boyd
Cloning and expression of the large zebrafish protocadherin gene, Fat.
Gene expression patterns : GEP 2005;5(4):483-90.
2005: K J Manton; Meaghan L Douglas; Sarah Netzel-Arnett; D R Fitzpatrick; David L Nicol; Andrew W Boyd; Judith A Clements; Toni M Antalis
Hypermethylation of the 5' CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis.
British journal of cancer 2005;92(4):760-9.
2004: Kylie J Ralston; Samantha L Hird; Xinhai Zhang; Judith L Scott; Boquan Jin; Rick F Thorne; Michael C Berndt; Andrew W Boyd; Gordon F Burns
The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large.
The Journal of biological chemistry 2004;279(32):33816-28.
2004: Juha P Himanen; Michael J Chumley; Martin Lackmann; Chen Li; William A Barton; Philip Jeffrey; Christopher Vearing; Detlef Geleick; David A Feldheim; Andrew W Boyd; Mark Henkemeyer; Dimitar B Nikolov
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling.
Nature neuroscience 2004;7(5):501-9.
2004: Fiona M Smith; Christopher Vearing; Martin Lackmann; Herbert Treutlein; Juha P Himanen; Ke Chen; Allan Saul; Dimitar B Nikolov; Andrew W Boyd
Dissecting the EphA3/Ephrin-A5 interactions using a novel functional mutagenesis screen.
The Journal of biological chemistry 2004;279(10):9522-31.
2002: Sana D Karam; Mirella Dottori; Kazushige Ogawa; Dr. Jeffrey Henderson; Andrew W Boyd; Elena B Pasquale; Mark Bothwell
EphA4 is not required for Purkinje cell compartmentation.
Brain research. Developmental brain research 2002;135(1-2):29-38.
2002: Isobel D Lawrenson; Sabine H Wimmer-Kleikamp; Peter Lock; Simone M Schoenwaelder; Michelle Down; Andrew W Boyd; Paul F Alewood; Martin Lackmann
Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling.
Journal of cell science 2002;115(Pt 5):1059-72.
2002: Mark G Coulthard; Shannon Duffy; Michelle Down; Betty Evans; Maryanne Power; Fiona Smith; Con Stylianou; Sabine Kleikamp; Andrew Oates; Martin Lackmann; Gordon F Burns; Andrew W Boyd
The role of the Eph-ephrin signalling system in the regulation of developmental patterning.
The International journal of developmental biology 2002;46(4):375-84.
2001: Andrew W Boyd; Martin Lackmann
Signals from Eph and ephrin proteins: a developmental tool kit.
Science's STKE : signal transduction knowledge environment 2001;2001(112):re20.
2001: Andreas Hüttmann; S L Liu; Andrew W Boyd; C L Li
Functional heterogeneity within rhodamine123(lo) Hoechst33342(lo/sp) primitive hemopoietic stem cells revealed by pyronin Y.
Experimental hematology 2001;29(9):1109-16.
2001: Jason R Coonan; Ursula Greferath; Jonathan Messenger; Lynne Hartley; Mark Murphy; Andrew W Boyd; Mirella Dottori; Mary P Galea; Perry F Bartlett
Development and reorganization of corticospinal projections in EphA4 deficient mice.
The Journal of comparative neurology 2001;436(2):248-62.
2001: M G Coulthard; J D Lickliter; N Subanesan; K Chen; GC Webb; A J Lowry; S Koblar; C D K Bottema; Andrew W Boyd
Characterization of the Epha1 receptor tyrosine kinase: expression in epithelial tissues.
Growth factors (Chur, Switzerland) 2001;18(4):303-17.
2001: K Kullander; N K Mather; Francesca Diella; Mirella Dottori; Andrew W Boyd; Rudiger Klein
Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo.
Neuron 2001;29(1):73-84.
2000: Shirley I Smith; Michelle Down; Andrew W Boyd; CL Li
Expression of the Wilms' tumor suppressor gene, WT1, reduces the tumorigenicity of the leukemic cell line M1 in C.B-17 scid/scid mice.
Cancer research 2000;60(4):808-14.
1999: Mirella Dottori; Michelle Down; Andreas Hüttmann; D R Fitzpatrick; Andrew W Boyd
Cloning and characterization of EphA3 (Hek) gene promoter: DNA methylation regulates expression in hematopoietic tumor cells.
Blood 1999;94(7):2477-86.
1999: Andrew Oates; Martin Lackmann; M A Power; C Brennan; L M Down; C Do; B Evans; N Holder; Andrew W Boyd
An early developmental role for eph-ephrin interaction during vertebrate gastrulation.
Mechanisms of development 1999;83(1-2):77-94.
1998: Mirella Dottori; Lynne Hartley; Mary P Galea; G Paxinos; Mark Polizzotto; T Kilpatrick; Perry F Bartlett; Mark Murphy; F Köntgen; Andrew W Boyd
EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13248-53.
1998: Martin Lackmann; Andrew Oates; Mirella Dottori; Fiona M Smith; C Do; M Power; L Kravets; Andrew W Boyd
Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization.
The Journal of biological chemistry 1998;273(32):20228-37.
1998: Shirley I Smith; D Weil; G R Johnson; Andrew W Boyd; CL Li
Expression of the Wilms' tumor suppressor gene, WT1, is upregulated by leukemia inhibitory factor and induces monocytic differentiation in M1 leukemic cells.
Blood 1998;91(3):764-73.
1997: Martin Lackmann; R J Mann; L Kravets; Fiona M Smith; T A Bucci; K F Maxwell; G J Howlett; jane elizabeth olsson; T Vanden Bos; D P Cerretti; Andrew W Boyd
Ligand for EPH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptor.
The Journal of biological chemistry 1997;272(26):16521-30.
1996: Martin Lackmann; T Bucci; R J Mann; L A Kravets; E Viney; F Smith; Robert L Moritz; W Carter; Richard J Simpson; Nicos A Nicola; K Mackwell; Edouard C Nice; Andrew Wilks; Andrew W Boyd
Purification of a ligand for the EPH-like receptor HEK using a biosensor-based affinity detection approach.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(6):2523-7.
1996: J D Lickliter; Fiona M Smith; jane elizabeth olsson; K L Mackwell; Andrew W Boyd
Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):145-50.
1994: J D Lickliter; C Glenn Begley; Andrew W Boyd; Jeff Szer; A P Grigg
Combined chemotherapy and granulocyte colony-stimulating factor (G-CSF) mobilise large numbers of peripheral blood progenitor cells in pretreated patients.
Leukemia & lymphoma 1994;15(1-2):91-7.