FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Catherine Vilchèze

Research Profile

Living Beings

Chemicals & Drugs

Procedures

Microbial Sensitivity Tests

Physiology

Concepts & Ideas

Structure-Activity Relationship

Co-author Network

Publications

TOP 3
Leah E Lim; Carol Ng; Santiago Ramón-García; William R Jacobs; Catherine Vilchèze; Charles J Thompson
Anthelmintic avermectins kill Mycobacterium tuberculosis, including multidrug-resistant clinical strains.
Dhinakaran Sambandan; Catherine Vilchèze; Brian Charles Weinrick; Laurent Kremer; Anil Ojha; Gurdyal S Besra; Dee N Dao; Sudagar S Gurcha; Graham F Hatfull; William R Jacobs
Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis.
Catherine Vilchèze; William R Jacobs
The combination of sulfamethoxazole, trimethoprim, and isoniazid or rifampin is bactericidal and prevents the emergence of drug resistance in Mycobacterium tuberculosis.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Catherine Vilchèze (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Leah E Lim; Carol Ng; Santiago Ramón-García; William R Jacobs; Catherine Vilchèze; Charles J Thompson
Anthelmintic avermectins kill Mycobacterium tuberculosis, including multidrug-resistant clinical strains.
Antimicrobial agents and chemotherapy 2013;57(2):1040-6.
2013: Dhinakaran Sambandan; Catherine Vilchèze; Brian Charles Weinrick; Laurent Kremer; Anil Ojha; Gurdyal S Besra; Dee N Dao; Sudagar S Gurcha; Graham F Hatfull; William R Jacobs
Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis.
mBio 2013;4(3):.
2012: Catherine Vilchèze; William R Jacobs
The combination of sulfamethoxazole, trimethoprim, and isoniazid or rifampin is bactericidal and prevents the emergence of drug resistance in Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2012;56(10):5142-8.
2011: Catherine Vilchèze; John R Walker; Michelle H. Larsen; Yossef Av-Gay; S Whitney Barnes; Richard J Glynne; William R. Jacobs Jr.
Coresistance to isoniazid and ethionamide maps to mycothiol biosynthetic genes in Mycobacterium bovis.
Antimicrobial agents and chemotherapy 2011;55(9):4422-3.
2011: Xia Xu; Catherine Vilchèze; Yossef Av-Gay; Anaximandro Gómez-Velasco; William R. Jacobs Jr.
Precise null deletion mutations of the mycothiol synthesis genes reveal their role in isoniazid and ethionamide resistance in Mycobacterium smegmatis.
Antimicrobial agents and chemotherapy 2011;55(7):3133-9.
2010: Virginie Molle; Gulcin Gulten; Catherine Vilchèze; Romain Veyron-Churlet; Isabelle Zanella-Cléon; James C Sacchettini; William R. Jacobs Jr.; Laurent Kremer
Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis.
Molecular microbiology 2010;78(6):1591-605.
2010: Anthony D Baughn; Jiaoyu Deng; Catherine Vilchèze; Angelica Riestra; John T Welch; William R. Jacobs Jr.; Oren Zimhony
Mutually exclusive genotypes for pyrazinamide and 5-chloropyrazinamide resistance reveal a potential resistance-proofing strategy.
Antimicrobial agents and chemotherapy 2010;54(12):5323-8.
2010: Feng Wang; Paras Jain; Gulcin Gulten; Zhen Liu; Yicheng Feng; Krishna Ganesula; Alifiya S Motiwala; Thomas R Ioerger; David Alland; Catherine Vilchèze; William R. Jacobs Jr.; James C Sacchettini
Mycobacterium tuberculosis dihydrofolate reductase is not a target relevant to the antitubercular activity of isoniazid.
Antimicrobial agents and chemotherapy 2010;54(9):3776-82.
2010: Patamaporn Pruksakorn; Masayoshi Arai; Naoyuki Kotoku; Catherine Vilchèze; Anthony D Baughn; Prashini Moodley; William R. Jacobs Jr.; Motomasa Kobayashi
Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria.
Bioorganic & medicinal chemistry letters 2010;20(12):3658-63.
2010: Catherine Vilchèze; Brian Charles Weinrick; Ka-Wing Wong; Bing Chen; William R. Jacobs Jr.
NAD+ auxotrophy is bacteriocidal for the tubercle bacilli.
Molecular microbiology 2010;76(2):365-77.
2009: Anthony D Baughn; Scott Garforth; Catherine Vilchèze; William R. Jacobs Jr.
An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis.
PLoS pathogens 2009;5(11):e1000662.
2009: Joel S Freundlich; Feng Wang; Catherine Vilchèze; Gulcin Gulten; Robert Langley; Guy A Schiehser; David P Jacobus; William R. Jacobs Jr.; James C Sacchettini
Triclosan derivatives: towards potent inhibitors of drug-sensitive and drug-resistant Mycobacterium tuberculosis.
ChemMedChem 2009;4(2):241-8.
2008: Catherine Vilchèze; Yossef Av-Gay; Rodgoun Attarian; Zhen Liu; Manzour Hernando Hazbón; Roberto Colangeli; Bing Chen; Weijun Liu; David Alland; James C Sacchettini; William R. Jacobs Jr.
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis.
Molecular microbiology 2008;69(5):1316-29.
2007: Catherine Vilchèze; William R. Jacobs Jr.
Isolation and analysis of Mycobacterium tuberculosis mycolic acids.
Current protocols in microbiology 2007;Chapter 10():Unit 10A.3.
2007: Roberto Colangeli; danica helb; Catherine Vilchèze; Manzour Hernando Hazbón; Chee-Gun Lee; Hassan Safi; Brendan Sayers; Irene Sardone; Marcus B Jones; Robert D Fleischmann; Scott N Peterson; William R. Jacobs Jr.; David Alland
Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis.
PLoS pathogens 2007;3(6):e87.
2007: Oren Zimhony; Catherine Vilchèze; Masayoshi Arai; John T Welch; William R. Jacobs Jr.
Pyrazinoic acid and its n-propyl ester inhibit fatty acid synthase type I in replicating tubercle bacilli.
Antimicrobial agents and chemotherapy 2007;51(2):752-4.
2007: Catherine Vilchèze; William R. Jacobs Jr.
The mechanism of isoniazid killing: clarity through the scope of genetics.
Annual review of microbiology 2007;61():35-50.
2006: Catherine Vilchèze; Feng Wang; Masayoshi Arai; Manzour Hernando Hazbón; Roberto Colangeli; Laurent Kremer; Torin R Weisbrod; David Alland; James C Sacchettini; William R. Jacobs Jr.
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.
Nature medicine 2006;12(9):1027-9.
2006: HECTOR MORBIDONI; Catherine Vilchèze; Laurent Kremer; Robert Bittman; James C Sacchettini; William R. Jacobs Jr.
Dual inhibition of mycobacterial fatty acid biosynthesis and degradation by 2-alkynoic acids.
Chemistry & biology 2006;13(3):297-307.
2005: Catherine Vilchèze; Torin R Weisbrod; Bing Chen; Laurent Kremer; Manzour Hernando Hazbón; Feng Wang; David Alland; James C Sacchettini; William R. Jacobs Jr.
Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.
Antimicrobial agents and chemotherapy 2005;49(2):708-20.
2004: Oren Zimhony; Catherine Vilchèze; William R. Jacobs Jr.
Characterization of Mycobacterium smegmatis expressing the Mycobacterium tuberculosis fatty acid synthase I (fas1) gene.
Journal of bacteriology 2004;186(13):4051-5.
2003: Laurent Kremer; Lynn Dover; HECTOR MORBIDONI; Catherine Vilchèze; William N Maughan; Alain Baulard; Shiao-Chun Tu; Nadine Honoré; Vojo Deretic; James C Sacchettini; Camille Locht; William R. Jacobs Jr.; Gurdyal S Besra
Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.
The Journal of biological chemistry 2003;278(23):20547-54.
2002: Michelle H. Larsen; Catherine Vilchèze; Laurent Kremer; Gurdyal S Besra; Linda Parsons; Max Salfinger; Leonid Heifets; Manzour H Hazbon; David Alland; James C Sacchettini; William R. Jacobs Jr.
Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis.
Molecular microbiology 2002;46(2):453-66.
2000: Oren Zimhony; Jeff S Cox; John T Welch; Catherine Vilchèze; William R. Jacobs Jr.
Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis.
Nature medicine 2000;6(9):1043-7.
2000: Catherine Vilchèze; HECTOR MORBIDONI; Torin R Weisbrod; H Iwamoto; M Kuo; James C Sacchettini; William R. Jacobs Jr.
Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis.
Journal of bacteriology 2000;182(14):4059-67.
1999: Denise A Rozwarski; Catherine Vilchèze; Michele Sugantino; Robert Bittman; James C Sacchettini
Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate.
The Journal of biological chemistry 1999;274(22):15582-9.
1998: Ian J Martins; Catherine Vilchèze; BC Mortimer; R Bittman; Trevor G Redgrave
Sterol side chain length and structure affect the clearance of chylomicron-like lipid emulsions in rats and mice.
Journal of lipid research 1998;39(2):302-12.
1996: Catherine Vilchèze; Todd P W McMullen; Ronald N McElhaney; Robert Bittman
The effect of side-chain analogues of cholesterol on the thermotropic phase behavior of 1-stearoyl-2-oleoylphosphatidylcholine bilayers: a differential scanning calorimetric study.
Biochimica et biophysica acta 1996;1279(2):235-42.
1995: P Mattjus; Robert Bittman; Catherine Vilchèze; J Peter Slotte
Lateral domain formation in cholesterol/phospholipid monolayers as affected by the sterol side chain conformation.
Biochimica et biophysica acta 1995;1240(2):237-47.
1995: Todd P W McMullen; Catherine Vilchèze; Ronald N McElhaney; Robert Bittman
Differential scanning calorimetric study of the effect of sterol side chain length and structure on dipalmitoylphosphatidylcholine thermotropic phase behavior.
Biophysical journal 1995;69(1):169-76.
1994: Catherine Vilchèze; Robert Bittman
An efficient asymmetric synthesis of diacylglycerols.
Journal of lipid research 1994;35(4):734-8.
1994: J Peter Slotte; M Jungner; Catherine Vilchèze; Robert Bittman
Effect of sterol side-chain structure on sterol-phosphatidylcholine interactions in monolayers and small unilamellar vesicles.
Biochimica et biophysica acta 1994;1190(2):435-43.