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Michael Boyd
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51
Cardellina, John
35
McMahon, James
30
Gustafson, Kirk
26
Pettit, George
24
Shoemaker, Robert
22
McKee, Tawnya
21
O'Keefe, Barry
21
Pannell, Lewis
19
Beutler, John
15
Gulakowski, RJ
13
Buckheit, Robert
13
Hallock, Yali
11
Fuller, RW
11
Rashid, Mohammad
10
Schmidt, Jean
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All Publications
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2007: Meragelman Tamara L; Willis Richard H; Woldemichael Girma M; Heaton Andrew; Murphy Peter T; Snader Kenneth M; Newman David J; van Soest Rob; Boyd Michael R; Cardellina John H; McKee Tawnya C
Candidaspongiolides, distinctive analogues of tedanolide from sponges of the genus Candidaspongia.
Journal of natural products 2007;70(7):1133-8.
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2005: Dijoux Marie-Geneviève; Schnabel Peter C; Hallock Yali F; Boswell Jamie L; Johnson Tanya R; Wilson Jennifer A; Ireland Chris M; van Soest Rob; Boyd Michael R; Barrows Louis R; Cardellina John H
Antitumor activity and distribution of pyrroloiminoquinones in the sponge genus Zyzzya.
Bioorganic & medicinal chemistry 2005;13(21):6035-44.
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2005: Mori Toshiyuki; O'Keefe Barry R; Sowder Raymond C; Bringans Scott; Gardella Roberta; Berg Shannon; Cochran Pamela; Turpin Jim A; Buckheit Robert W; McMahon James B; Boyd Michael R
Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp.
The Journal of biological chemistry 2005;280(10):9345-53.
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2004: Bringans Scott D; O'Keefe Barry R; Bray Michael; Whitehouse Chris A; Boyd Michael R
Development of a fluorescent microplate assay for determining cyanovirin-N levels in plasma.
Analytical and bioanalytical chemistry 2004;380(2):269-74.
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2004: Oku Naoya; Gustafson Kirk R; Cartner Laura K; Wilson Jennifer A; Shigematsu Nobuharu; Hess Sonja; Pannell Lewis K; Boyd Michael R; McMahon James B
Neamphamide A, a new HIV-inhibitory depsipeptide from the Papua New Guinea marine sponge Neamphius huxleyi.
Journal of natural products 2004;67(8):1407-11.
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2004: Charan Romila D; McKee Tawnya C; Boyd Michael R
Cytotoxic alkaloids from the marine sponge Thorectandra sp.
Natural product research 2004;18(3):225-9.
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2004: Milanowski Dennis J; Gustafson Kirk R; Rashid Mohammad A; Pannell Lewis K; McMahon James B; Boyd Michael R
Gymnangiamide, a cytotoxic pentapeptide from the marine hydroid Gymnangium regae.
The Journal of organic chemistry 2004;69(9):3036-42.
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2004: Milanowski Dennis J; Rashid Mohammad A; Gustafson Kirk R; O'Keefe Barry R; Nawrocki Joseph P; Pannell Lewis K; Boyd Michael R
Cyclonellin, a new cyclic octapeptide from the marine sponge Axinella carteri.
Journal of natural products 2004;67(3):441-4.
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2003: O'Keefe Barry R; Smee Donald F; Turpin Jim A; Saucedo Carrie J; Gustafson Kirk R; Mori Toshiyuki; Blakeslee Dennis; Buckheit Robert; Boyd Michael R
Potent anti-influenza activity of cyanovirin-N and interactions with viral hemagglutinin.
Antimicrobial agents and chemotherapy 2003;47(8):2518-25.
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2003: Barrientos Laura G; O'Keefe Barry R; Bray Mike; Sanchez Anthony; Gronenborn Angela M; Boyd Michael R
Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus.
Antiviral research 2003;58(1):47-56.
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2003: Bokesch Heidi R; O'Keefe Barry R; McKee Tawnya C; Pannell Lewis K; Patterson Gregory M L; Gardella Roberta S; Sowder Raymond C; Turpin Jim; Watson Karen; Buckheit Robert W; Boyd Michael R
A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium.
Biochemistry 2003;42(9):2578-84.
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2002: Shenoy Shilpa R; Barrientos Laura G; Ratner Daniel M; O'Keefe Barry R; Seeberger Peter H; Gronenborn Angela M; Boyd Michael R
Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization.
Chemistry & biology 2002;9(10):1109-18.
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2002: Erickson Karen L; Gustafson Kirk R; Pannell Lewis K; Beutler John A; Boyd Michael R
New dimeric macrolide glycosides from the marine sponge Myriastra clavosa.
Journal of natural products 2002;65(9):1303-6.
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2002: Pettit George R; Ducki Sylvie; Tan Rui; Gardella Roberta S; McMahon James B; Boyd Michael R; Pettit George R; Blumberg Peter M; Lewin Nancy E; Doubek Dennis L; Tackett Larry P; Williams Michael D
Isolation and structure of pedilstatin from a republic of maldives Pedilanthus sp.
Journal of natural products 2002;65(9):1262-5.
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2002: Meragelman Karina M; West Lyndon M; Northcote Peter T; Pannell Lewis K; McKee Tawnya C; Boyd Michael R
Unusual sulfamate indoles and a novel indolo[3,2-a]carbazole from Ancorina sp.
The Journal of organic chemistry 2002;67(19):6671-7.
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2002: Rashid Mohammad A; Gustafson Kirk R; Crouch Ronald C; Groweiss Amiram; Pannell Lewis K; Van Que N; Boyd Michael R
Application of high-field NMR and cryogenic probe technologies in the structural elucidation of poecillastrin a, a new antitumor macrolide lactam from the sponge poecillastra species.
Organic letters 2002;4(19):3293-6.
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2002: Botos Istvan; O'Keefe Barry R; Shenoy Shilpa R; Cartner Laura K; Ratner Daniel M; Seeberger Peter H; Boyd Michael R; Wlodawer Alexander
Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides.
The Journal of biological chemistry 2002;277(37):34336-42.
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2002: Giomarelli Barbara; Provvedi Roberta; Meacci Francesca; Maggi Tiziana; Medaglini Donata; Pozzi Gianni; Mori Toshiyuki; McMahon James B; Gardella Roberta; Boyd Michael R
The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1.
AIDS (London, England) 2002;16(10):1351-6.
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2002: Botos Istvan; Mori Toshiyuki; Cartner Laura K; Boyd Michael R; Wlodawer Alexander
Domain-swapped structure of a mutant of cyanovirin-N.
Biochemical and biophysical research communications 2002;294(1):184-90.
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2002: Barrientos Laura G; Louis John M; Botos Istvan; Mori Toshiyuki; Han Zhaozhong; O'Keefe Barry R; Boyd Michael R; Wlodawer Alexander; Gronenborn Angela M
The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures.
Structure (London, England : 1993) 2002;10(5):673-86.
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2002: Beutler John A; McMahon James B; Johnson Tanya R; O'Keefe Barry R; Buzzell Randy A; Robbins Danielle; Gardella Roberta; Wilson Jennifer; Boyd Michael R
High throughput screening for cyanovirin-N mimetics binding to HIV-1 gp41.
Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 2002;7(2):105-10.
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2002: Charan Romila D; McKee Tawnya C; Boyd Michael R
Thorectandrols C, D, and E, new sesterterpenes from the marine sponge Thorectandra sp.
Journal of natural products 2002;65(4):492-5.
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2002: Barrientos Laura G; Louis John M; Hung Jason; Smith Trent H; O'Keefe Barry R; Gardella Roberta S; Mori Toshiyuki; Boyd Michael R; Gronenborn Angela M
Design and initial characterization of a circular permuted variant of the potent HIV-inactivating protein cyanovirin-N.
Proteins 2002;46(2):153-60.
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2001: Meragelman K M; McKee T C; Boyd M R
10-Demethoxystegane, a new lignan from Steganotaenia araliacea.
Journal of natural products 2001;64(11):1480-2.
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2001: Rashid M A; Gustafson K R; Boyd M R
New cytotoxic N-methylated beta-carboline alkaloids from the marine ascidian Eudistoma gilboverde.
Journal of natural products 2001;64(11):1454-6.
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2001: Rashid M A; Cantrell C L; Gustafson K R; Boyd M R
Chondropsin D, a new 37-membered-ring macrolide lactam from the marine sponge Chondropsis species.
Journal of natural products 2001;64(10):1341-4.
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2001: Rashid M A; Gustafson K R; Boyd M R
A new isoquinoline alkaloid from the marine sponge Haliclona species.
Journal of natural products 2001;64(9):1249-50.
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2001: Pettit G R; Moser B R; Boyd M R; Schmidt J M; Pettit R K; Chapuis J C
Antineoplastic agents 460. Synthesis of combretastatin A-2 prodrugs.
Anti-cancer drug design 2001;16(4-5):185-93.
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2001: Charan R D; McKee T C; Boyd M R
Thorectandrols A and B, new cytotoxic sesterterpenes from the marine sponge Thorectandra species.
Journal of natural products 2001;64(5):661-3.
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2001: Bolmstedt A J; O'Keefe B R; Shenoy S R; McMahon J B; Boyd M R
Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner.
Molecular pharmacology 2001;59(5):949-54.
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2001: Shenoy S R; O'Keefe B R; Bolmstedt A J; Cartner L K; Boyd M R
Selective interactions of the human immunodeficiency virus-inactivating protein cyanovirin-N with high-mannose oligosaccharides on gp120 and other glycoproteins.
The Journal of pharmacology and experimental therapeutics 2001;297(2):704-10.
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2001: Meragelman K M; McKee T C; Boyd M R
Anti-HIV prenylated flavonoids from Monotes africanus.
Journal of natural products 2001;64(4):546-8.
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2001: Meragelman K M; McKee T C; Boyd M R
New cytotoxic isomalabaricane triterpenes from the sponge Jaspis species.
Journal of natural products 2001;64(3):389-92.
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2001: Bokesch H R; Pannell L K; Cochran P K; Sowder R C; McKee T C; Boyd M R
A novel anti-HIV macrocyclic peptide from Palicourea condensata.
Journal of natural products 2001;64(2):249-50.
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2001: McNulty J; Mao J; Gibe R; Mo R; Wolf S; Pettit G R; Herald D L; Boyd M R
Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore.
Bioorganic & medicinal chemistry letters 2001;11(2):169-72.
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2001: Rashid M A; Gustafson K R; Cartner L K; Shigematsu N; Pannell L K; Boyd M R
Microspinosamide, a new HIV-inhibitory cyclic depsipeptide from the marine sponge Sidonops microspinosa.
Journal of natural products 2001;64(1):117-21.
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2001: Rashid M A; Gustafson K R; Cardellina J H; Boyd M R
Absolute stereochemistry and anti-HIV activity of minquartynoic acid, a polyacetylene from Ochanostachys amentacea.
Natural product letters 2001;15(1):21-6.
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2000: Pettit G R; Minardi M D; Boyd M R; Pettit R K
Antineoplastic agents 463. Synthesis of combretastatin A-3 diphosphate prodrugs.
Anti-cancer drug design 2000;15(6):397-403.
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2000: Groweiss A; Cardellina J H; Boyd M R
HIV-Inhibitory prenylated xanthones and flavones from Maclura tinctoria.
Journal of natural products 2000;63(11):1537-9.
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2000: O'Keefe B R; Shenoy S R; Xie D; Zhang W; Muschik J M; Currens M J; Chaiken I; Boyd M R
Analysis of the interaction between the HIV-inactivating protein cyanovirin-N and soluble forms of the envelope glycoproteins gp120 and gp41.
Molecular pharmacology 2000;58(5):982-92.
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2000: Pettit G R; Lippert J W; Boyd M R; Verdier-Pinard P; Hamel E
Antineoplastic agents 442. Synthesis and biological activities of dioxostatin.
Anti-cancer drug design 2000;15(5):361-71.
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2000: Beutler J A; McCall K L; Herbert K; Johnson T; Shoemaker R H; Boyd M R
Cytotoxic clerodane diterpene esters from Laetia corymbulosa.
Phytochemistry 2000;55(3):233-6.
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2000: Davies-Coleman M T; Gustafson K R; Cantrell C L; Beutler J A; Pannell L K; Boyd M R
Stolonic acids A and B, new cytotoxic cyclic peroxides from an Indian Ocean ascidian Stolonica species.
Journal of natural products 2000;63(10):1411-3.
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2000: Charan R D; Munro M H; O'Keefe B R; Sowder RCII; McKee T C; Currens M J; Pannell L K; Boyd M R
Isolation and characterization of Myrianthus holstii lectin, a potent HIV-1 inhibitory protein from the plant Myrianthus holstii(1).
Journal of natural products 2000;63(8):1170-4.
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2000: Rashid M A; Gustafson K R; Boswell J L; Boyd M R
Haligramides A and B, two new cytotoxic hexapeptides from the marine sponge Haliclona nigra.
Journal of natural products 2000;63(7):956-9.
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2000: Pettit G R; Grealish M P; Herald D L; Boyd M R; Hamel E; Pettit R K
Antineoplastic agents. 443. Synthesis of the cancer cell growth inhibitor hydroxyphenstatin and its sodium diphosphate prodrug.
Journal of medicinal chemistry 2000;43(14):2731-7.
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2000: McMahon J B; Beutler J A; O'Keefe B R; Goodrum C B; Myers M A; Boyd M R
Development of a cyanovirin-N-HIV-1 gp120 binding assay for high throughput screening of natural product extracts by time-resolved fluorescence.
Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 2000;5(3):169-76.
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2000: Pettit G R; Knight J C; Collins J C; Herald D L; Pettit R K; Boyd M R; Young V G
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
Journal of natural products 2000;63(6):793-8.
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2000: Beutler J A; McCall K L; Herbert K; Herald D L; Pettit G R; Johnson T; Shoemaker R H; Boyd M R
Novel cytotoxic diterpenes from Casearia arborea.
Journal of natural products 2000;63(5):657-61.
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2000: Rashid M A; Gustafson K R; Boyd M R
HIV-inhibitory cembrane derivatives from a Philippines collection of the soft coral Lobophytum species.
Journal of natural products 2000;63(4):531-3.
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2000: Meragelman K M; McKee T C; Boyd M R
Siamenol, a new carbazole alkaloid from Murraya siamensis.
Journal of natural products 2000;63(3):427-8.
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2000: Gustafson K R; Walton L K; Sowder R C; Johnson D G; Pannell L K; Cardellina J H; Boyd M R
New circulin macrocyclic polypeptides from Chassalia parvifolia.
Journal of natural products 2000;63(2):176-8.
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2000: Hallock Y F; Sowder R C; Pannell L K; Hughes C B; Johnson D G; Gulakowski R; Cardellina J H; Boyd M R
Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.
The Journal of organic chemistry 2000;65(1):124-8.
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1999: Dai J R; Hallock Y F; Cardellina II J H; Boyd M R
20-O-beta-glucopyranosyl camptothecin from mostuea brunonis: A potential camptothecin pro-drug with improved solubility.
Journal of natural products 1999;62(10):1427-9.
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1999: Gamble W R; Durso N A; Fuller R W; Westergaard C K; Johnson T R; Sackett D L; Hamel E; Cardellina J H; Boyd M R
Cytotoxic and tubulin-interactive hemiasterlins from Auletta sp. and Siphonochalina spp. sponges.
Bioorganic & medicinal chemistry 1999;7(8):1611-5.
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1999: Bokesch H R; Groweiss A; McKee T C; Boyd M R
Laxifloranone, a new phloroglucinol derivative from Marila laxiflora.
Journal of natural products 1999;62(8):1197-9.
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1999: Dijoux M G; Gamble W R; Hallock Y F; Cardellina J H; van Soest R; Boyd M R
A new discorhabdin from two sponge genera.
Journal of natural products 1999;62(4):636-7.
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1999: Bokesch H R; Blunt J W; Westergaard C K; Cardellina J H; Johnson T R; Michael J A; McKee T C; Hollingshead M G; Boyd M R
Alertenone, a dimer of suberosenone from Alertigorgia sp.
Journal of natural products 1999;62(4):633-5.
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1999: Pettit G R; Toki B E; Herald D L; Boyd M R; Hamel E; Pettit R K; Chapuis J C
Antineoplastic agents. 410. Asymmetric hydroxylation of trans-combretastatin A-4.
Journal of medicinal chemistry 1999;42(8):1459-65.
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1999: Fuller R W; Blunt J W; Boswell J L; Cardellina J H; Boyd M R
Guttiferone F, the first prenylated benzophenone from Allanblackia stuhlmannii.
Journal of natural products 1999;62(1):130-2.
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1999: Fuller R W; Westergaard C K; Collins J W; Cardellina J H; Boyd M R
Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis.
Journal of natural products 1999;62(1):67-9.
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1998: Beutler J A; Shoemaker R H; Johnson T; Boyd M R
Cytotoxic geranyl stilbenes from Macaranga schweinfurthii.
Journal of natural products 1998;61(12):1509-12.
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1998: McKee T C; Covington C D; Fuller R W; Bokesch H R; Young S; Cardellina II J H; Kadushin M R; Soejarto D D; Stevens P F; Cragg G M; Boyd M R
Pyranocoumarins from tropical species of the genus Calophyllum: a chemotaxonomic study of extracts in the National Cancer Institute collection.
Journal of natural products 1998;61(10):1252-6.
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1998: Hallock Y F; Cardellina J H; Schäffer M; Bringmann G; François G; Boyd M R
Korundamine A, a novel HIV-inhibitory and antimalarial "hybrid" naphthylisoquinoline alkaloid heterodimer from Ancistrocladus korupensis.
Bioorganic & medicinal chemistry letters 1998;8(13):1729-34.
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1998: Mariner J M; McMahon J B; O'Keefe B R; Nagashima K; Boyd M R
The HIV-inactivating protein, cyanovirin-N, does not block gp120-mediated virus-to-cell binding.
Biochemical and biophysical research communications 1998;248(3):841-5.
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1998: O'Keefe B R; Erim T; Beutler J A; Cardellina J H; Gulakowski R J; Krepps B L; McMahon J B; Sowder R C; Johnson D G; Buckheit R W; Halliday S; Boyd M R
Isolation and characterization of adociavirin, a novel HIV-inhibitory protein from the sponge Adocia sp.
FEBS letters 1998;431(1):85-90.
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1998: Pettit G R; Tan R; Xu J; Ichihara Y; Williams M D; Boyd M R
Antineoplastic agents. 398. Isolation and structure elucidation of cephalostatins 18 and 19.
Journal of natural products 1998;61(7):955-8.
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1998: Beutler J A; Hamel E; Vlietinck A J; Haemers A; Rajan P; Roitman J N; Cardellina J H; Boyd M R
Structure-activity requirements for flavone cytotoxicity and binding to tubulin.
Journal of medicinal chemistry 1998;41(13):2333-8.
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1998: Pettit G R; Srirangam J K; Barkoczy J; Williams M D; Boyd M R; Hamel E; Pettit R K; Hogan F; Bai R; Chapuis J C; McAllister S C; Schmidt J M
Antineoplastic agents 365. Dolastatin 10 SAR probes.
Anti-cancer drug design 1998;13(4):243-77.
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1998: Pettit G R; Toki B; Herald D L; Verdier-Pinard P; Boyd M R; Hamel E; Pettit R K
Antineoplastic agents. 379. Synthesis of phenstatin phosphate.
Journal of medicinal chemistry 1998;41(10):1688-95.
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1998: Dai J R; Hallock Y F; Cardellina J H; Boyd M R
HIV-inhibitory and cytotoxic oligostilbenes from the leaves of Hopea malibato.
Journal of natural products 1998;61(3):351-3.
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1998: Mori T; Gustafson K R; Pannell L K; Shoemaker R H; Wu L; McMahon J B; Boyd M R
Recombinant production of cyanovirin-N, a potent human immunodeficiency virus-inactivating protein derived from a cultured cyanobacterium.
Protein expression and purification 1998;12(2):151-8.
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1998: Pettit G R; Flahive E J; Boyd M R; Bai R; Hamel E; Pettit R K; Schmidt J M
Antineoplastic agents 360. Synthesis and cancer cell growth inhibitory studies of dolastatin 15 structural modifications.
Anti-cancer drug design 1998;13(1):47-66.
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1997: O'Keefe B R; Beutler J A; Cardellina J H; Prather T R; Shoemaker R H; Sowder R C; Henderson L E; Pannell L K; Boyd M R
Isolation of a novel Kunitz family protease inhibitor in association with Tethya hemolysin from the sponge Tethya ingalli.
Journal of natural products 1997;60(11):1094-9.
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1997: Mori T; Shoemaker R H; McMahon J B; Gulakowski R J; Gustafson K R; Boyd M R
Construction and enhanced cytotoxicity of a [cyanovirin-N]-[Pseudomonas exotoxin] conjugate against human immunodeficiency virus-infected cells.
Biochemical and biophysical research communications 1997;239(3):884-8.
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1997: Gustafson K R; Sowder R C; Henderson L E; Cardellina J H; McMahon J B; Rajamani U; Pannell L K; Boyd M R
Isolation, primary sequence determination, and disulfide bond structure of cyanovirin-N, an anti-HIV (human immunodeficiency virus) protein from the cyanobacterium Nostoc ellipsosporum.
Biochemical and biophysical research communications 1997;238(1):223-8.
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1997: Mori T; Shoemaker R H; Gulakowski R J; Krepps B L; McMahon J B; Gustafson K R; Pannell L K; Boyd M R
Analysis of sequence requirements for biological activity of cyanovirin-N, a potent HIV (human immunodeficiency virus)-inactivating protein.
Biochemical and biophysical research communications 1997;238(1):218-22.
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1997: Beutler J A; Kashman Y; Pannell L K; Cardellina J H; Alexander M R; Balaschak M S; Prather T R; Shoemaker R H; Boyd M R
Isolation and characterization of novel cytotoxic saponins from Archidendron ellipticum.
Bioorganic & medicinal chemistry 1997;5(8):1509-17.
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1997: Pettit G R; Xu J P; Hogan F; Williams M D; Doubek D L; Schmidt J M; Cerny R L; Boyd M R
Isolation and structure of the human cancer cell growth inhibitory cyclodepsipeptide dolastatin 16.
Journal of natural products 1997;60(8):752-4.
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1997: Hallock Y F; Manfredi K P; Dai J R; Cardellina J H; Gulakowski R J; McMahon J B; Schäffer M; Stahl M; Gulden K P; Bringmann G; François G; Boyd M R
Michellamines D-F, new HIV-inhibitory dimeric naphthylisoquinoline alkaloids, and korupensamine E, a new antimalarial monomer, from Ancistrocladus korupensis.
Journal of natural products 1997;60(7):677-83.
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1997: Boyd M R; Gustafson K R; McMahon J B; Shoemaker R H; O'Keefe B R; Mori T; Gulakowski R J; Wu L; Rivera M I; Laurencot C M; Currens M J; Cardellina J H; Buckheit R W; Nara P L; Pannell L K; Sowder R C; Henderson L E
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.
Antimicrobial agents and chemotherapy 1997;41(7):1521-30.
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1997: McKee T C; Bokesch H R; McCormick J L; Rashid M A; Spielvogel D; Gustafson K R; Alavanja M M; Cardelline J H; Boyd M R
Isolation and characterization of new anti-HIV and cytotoxic leads from plants, marine, and microbial organisms.
Journal of natural products 1997;60(5):431-8.
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1997: O'Keefe B R; Beutler J A; Cardellina J H; Gulakowski R J; Krepps B L; McMahon J B; Sowder R C; Henderson L E; Pannell L K; Pomponi S A; Boyd M R
Isolation and characterization of niphatevirin, a human-immunodeficiency-virus-inhibitory glycoprotein from the marine sponge Niphates erecta.
European journal of biochemistry / FEBS 1997;245(1):47-53.
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1997: Pettit G R; McNulty J; Herald D L; Doubek D L; Chapuis J C; Schmidt J M; Tackett L P; Boyd M R
Antineoplastic agents. 362. Isolation and X-ray crystal structure of dibromophakellstatin from the Indian ocean sponge Phakellia mauritiana.
Journal of natural products 1997;60(2):180-3.
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1997: Groweiss A; Cardellina J H; Pannell L K; Uyakul D; Kashman Y; Boyd M R
Novel cytotoxic, alkylated hydroquinones from Lannea welwitschii.
Journal of natural products 1997;60(2):116-21.
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1997: Gulakowski R J; McMahon J B; Buckheit R W; Gustafson K R; Boyd M R
Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV).
Antiviral research 1997;33(2):87-97.
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1996: McCormick J L; McKee T C; Cardellina J H; Leid M; Boyd M R
Cytotoxic triterpenes from a marine sponge, Stelletta sp.
Journal of natural products 1996;59(11):1047-50.
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1996: Vistica D T; Kenney S; Hursey M; Boyd M R
Role of membrane potential in the accumulation of quaternized ellipticines by human tumor cell lines.
The Journal of pharmacology and experimental therapeutics 1996;279(2):1018-25.
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1996: Currens M J; Mariner J M; McMahon J B; Boyd M R
Kinetic analysis of inhibition of human immunodeficiency virus type-1 reverse transcriptase by calanolide A.
The Journal of pharmacology and experimental therapeutics 1996;279(2):652-61.
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1996: Currens M J; Gulakowski R J; Mariner J M; Moran R A; Buckheit R W; Gustafson K R; McMahon J B; Boyd M R
Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1.
The Journal of pharmacology and experimental therapeutics 1996;279(2):645-51.
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1996: Galinis D L; Fuller R W; McKee T C; Cardellina J H; Gulakowski R J; McMahon J B; Boyd M R
Structure-activity modifications of the HIV-1 inhibitors (+)-calanolide A and (-)-calanolide B.
Journal of medicinal chemistry 1996;39(22):4507-10.
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1996: Dai J R; Hallock Y F; Cardellina JH I I; Gray G N; Boyd M R
Triangulynes A-H and trangulynic acid, new cytotxic polyacetylenes from the marine sponge Pellina triangulata.
Journal of natural products 1996;59(9):860-5.
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1996: McKee T C; Fuller R W; Covington C D; Cardellina J H; Gulakowski R J; Krepps B L; McMahon J B; Boyd M R
New pyranocoumarins isolated from Calophyllum lanigerum and Calophyllum teysmannii.
Journal of natural products 1996;59(8):754-8.
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1996: Bernart M W; Cardellina J H; Balaschak M S; Alexander M R; Shoemaker R H; Boyd M R
Cytotoxic falcarinol oxylipins from Dendropanax arboreus.
Journal of natural products 1996;59(8):748-53.
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1996: McCormick J L; McKee T C; Cardellina J H; Boyd M R
HIV inhibitory natural products. 26. Quinoline alkaloids from Euodia roxburghiana.
Journal of natural products 1996;59(5):469-71.
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1996: Rashid M A; Gustafson K R; Cardellina J H; Boyd M R
A benzoic acid glycoside from Geniostoma antherotrichum.
Phytochemistry 1996;41(4):1205-7.
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1996: Dai J R; Hallock Y F; Cardellina J H; Boyd M R
Vasculyne, a new cytotoxic acetylenic alcohol from the marine sponge Cribrochalina vasculum.
Journal of natural products 1996;59(1):88-9.
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1996: McMahon J B; Buckheit R W; Gulakowski R J; Currens M J; Vistica D T; Shoemaker R H; Stinson S F; Russell J D; Bader J P; Narayanan V L; Schultz R J; Brouwer W G; Felauer E E; Boyd M R
Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor.
The Journal of pharmacology and experimental therapeutics 1996;276(1):298-305.
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1995: Erickson K L; Beutler J A; Gray G N; Cardellina J H; Boyd M R
Majapolene A, a cytotoxic peroxide, and related sesquiterpenes from the red alga Laurencia majuscula.
Journal of natural products 1995;58(12):1848-60.
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1995: Hallock Y F; Cardellina J H; Balaschak M S; Alexander M R; Prather T R; Shoemaker R H; Boyd M R
Antitumor activity and stereochemistry of acetylenic alcohols from the sponge Cribrochalina vasculum.
Journal of natural products 1995;58(12):1801-7.
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1995: Pettit G R; Srirangam J K; Barkoczy J; Williams M D; Durkin K P; Boyd M R; Bai R; Hamel E; Schmidt J M; Chapuis J C
Antineoplastic agents 337. Synthesis of dolastatin 10 structural modifications.
Anti-cancer drug design 1995;10(7):529-44.
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1995: Rashid M A; Gustafson K R; Cardellina J H; Boyd M R
Mycalolides D and E, new cytotoxic macrolides from a collection of the stony coral Tubastrea faulkneri.
Journal of natural products 1995;58(7):1120-5.
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1995: Beutler J A; Kashman Y; Tischler M; Cardellina J H; Gray G N; Currens M J; Wall M E; Wani M C; Boyd M R
A reinvestigation of Maprounea triterpenes.
Journal of natural products 1995;58(7):1039-46.
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1995: Pettit G R; Temple C; Narayanan V L; Varma R; Simpson M J; Boyd M R; Rener G A; Bansal N
Antineoplastic agents 322. synthesis of combretastatin A-4 prodrugs.
Anti-cancer drug design 1995;10(4):299-309.
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1995: Pettit G R; Tan R; Ichihara Y; Williams M D; Doubek D L; Tackett L P; Schmidt J M; Cerny R L; Boyd M R; Hooper J N
Antineoplastic agents, 325. Isolation and structure of the human cancer cell growth inhibitory cyclic octapeptides phakellistatin 10 and 11 from Phakellia sp.
Journal of natural products 1995;58(6):961-5.
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1995: McKee T C; Cardellina J H; Dreyer G B; Boyd M R
The pseudocalanolides: structure revision of calanolides C and D.
Journal of natural products 1995;58(6):916-20.
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1995: Pettit G R; Singh S B; Boyd M R; Hamel E; Pettit R K; Schmidt J M; Hogan F
Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a)
Journal of medicinal chemistry 1995;38(10):1666-72.
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1995: Erickson K L; Beutler J A; Cardellina J H; McMahon J B; Newman D J; Boyd M R
A novel phorbol ester from Excoecaria agallocha.
Journal of natural products 1995;58(5):769-72.
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1995: Pettit G R; Freeman S; Simpson M J; Thompson M A; Boyd M R; Williams M D; Pettit G R; Doubek D L
Antineoplastic agents 320: synthesis of a practical pancratistatin prodrug.
Anti-cancer drug design 1995;10(3):243-50.
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1995: Rashid M A; Gustafson K R; Cardellina J H; Boyd M R
Patellamide F, A new cytotoxic cyclic peptide from the colonial ascidian Lissoclinum patella.
Journal of natural products 1995;58(4):594-7.
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1995: Buckheit R W; Fliakas-Boltz V; Decker W D; Roberson J L; Stup T L; Pyle C A; White E L; McMahon J B; Currens M J; Boyd M R
Comparative anti-HIV evaluation of diverse HIV-1-specific reverse transcriptase inhibitor-resistant virus isolates demonstrates the existence of distinct phenotypic subgroups.
Antiviral research 1995;26(2):117-32.
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1995: McMahon J B; Currens M J; Gulakowski R J; Buckheit R W; Lackman-Smith C; Hallock Y F; Boyd M R
Michellamine B, a novel plant alkaloid, inhibits human immunodeficiency virus-induced cell killing by at least two distinct mechanisms.
Antimicrobial agents and chemotherapy 1995;39(2):484-8.
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1995: Kenney S; Vistica D T; Linden H; Boyd M R
Uptake and cytotoxicity of 9-methoxy-N2-methylellipticinium acetate in human brain and non-brain tumor cell lines.
Biochemical pharmacology 1995;49(1):23-32.
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1994: Hallock Y F; Dai J; Bokesch H R; Dillah K B; Manfredi K P; Cardellina J H; Boyd M R
Preparative separation of naphthyltetrahydroisoquinoline alkaloids from Ancistrocladus korupensis by centrifugal partition chromatography.
Journal of chromatography. A 1994;688(1-2):83-8.
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1994: Dai J R; Decosterd L A; Gustafson K R; Cardellina J H; Gray G N; Boyd M R
Novel naphthoquinones from Conospermum incurvum.
Journal of natural products 1994;57(11):1511-6.
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1994: Fuller R W; Cardellina J H; Cragg G M; Boyd M R
Cucurbitacins: differential cytotoxicity, dereplication and first isolation from Gonystylus keithii.
Journal of natural products 1994;57(10):1442-5.
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1994: Buckheit R W; Fliakas-Boltz V; Decker W D; Roberson J L; Pyle C A; White E L; Bowdon B J; McMahon J B; Boyd M R; Bader J P
Biological and biochemical anti-HIV activity of the benzothiadiazine class of nonnucleoside reverse transcriptase inhibitors.
Antiviral research 1994;25(1):43-56.
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1994: Acton E M; Narayanan V L; Risbood P A; Shoemaker R H; Vistica D T; Boyd M R
Anticancer specificity of some ellipticinium salts against human brain tumors in vitro.
Journal of medicinal chemistry 1994;37(14):2185-9.
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1994: Boyd M R; Hallock Y F; Cardellina J H; Manfredi K P; Blunt J W; McMahon J B; Buckheit R W; Bringmann G; Schäffer M; Cragg G M
Anti-HIV michellamines from Ancistrocladus korupensis.
Journal of medicinal chemistry 1994;37(12):1740-5.
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1994: Vistica D T; Kenney S; Hursey M L; Boyd M R
Cellular uptake as a determinant of cytotoxicity of quaternized ellipticines to human brain tumor cells.
Biochemical and biophysical research communications 1994;200(3):1762-8.
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1994: Kashman Y; Bernart M W; Tischler M; Cardellina J H; Boyd M R
Koumbalones A and B, new casbane diterpenes from Maprounea africana.
Journal of natural products 1994;57(3):426-30.
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1994: Pettit G R; Xu J P; Williams M D; Christie N D; Doubek D L; Schmidt J M; Boyd M R
Isolation and structure of cephalostatins 10 and 11.
Journal of natural products 1994;57(1):52-63.
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1994: Cragg G M; Boyd M R; Cardellina J H; Newman D J; Snader K M; McCloud T G
Ethnobotany and drug discovery: the experience of the US National Cancer Institute.
Ciba Foundation symposium 1994;185():178-90; discussion 190-6.
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1993: Beutler J A; Cardellina J H; Prather T; Shoemaker R H; Boyd M R; Snader K M
A cytotoxic beta-carboline from the bryozoan Catenicella cribraria.
Journal of natural products 1993;56(10):1825-6.
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1993: Beutler J A; Cardellina J H; Gray G N; Prather T R; Shoemaker R H; Boyd M R; Lin C M; Hamel E; Cragg G M
Two new cytotoxic chalcones from Calythropsis aurea.
Journal of natural products 1993;56(10):1718-22.
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1993: Pettit G R; Pettit G R; Backhaus R A; Boyd M R; Meerow A W
Antineoplastic agents, 256. Cell growth inhibitory isocarbostyrils from Hymenocallis.
Journal of natural products 1993;56(10):1682-7.
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1993: Cardellina J H; Munro M H; Fuller R W; Manfredi K P; McKee T C; Tischler M; Bokesch H R; Gustafson K R; Beutler J A; Boyd M R
A chemical screening strategy for the dereplication and prioritization of HIV-inhibitory aqueous natural products extracts.
Journal of natural products 1993;56(7):1123-9.
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1993: Hizi A; Tal R; Shaharabany M; Currens M J; Boyd M R; Hughes S H; McMahon J B
Specific inhibition of the reverse transcriptase of human immunodeficiency virus type 1 and the chimeric enzymes of human immunodeficiency virus type 1 and type 2 by nonnucleoside inhibitors.
Antimicrobial agents and chemotherapy 1993;37(5):1037-42.
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1993: Boyer P L; Currens M J; McMahon J B; Boyd M R; Hughes S H
Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase.
Journal of virology 1993;67(4):2412-20.
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1992: Fuller R W; Cardellina J H; Kato Y; Brinen L S; Clardy J; Snader K M; Boyd M R
A pentahalogenated monoterpene from the red alga Portieria hornemannii produces a novel cytotoxicity profile against a diverse panel of human tumor cell lines.
Journal of medicinal chemistry 1992;35(16):3007-11.
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1992: Stinson S F; Alley M C; Kopp W C; Fiebig H H; Mullendore L A; Pittman A F; Kenney S; Keller J; Boyd M R
Morphological and immunocytochemical characteristics of human tumor cell lines for use in a disease-oriented anticancer drug screen.
Anticancer research 1992;12(4):1035-53.
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1992: Kashman Y; Gustafson K R; Fuller R W; Cardellina J H; McMahon J B; Currens M J; Buckheit R W; Hughes S H; Cragg G M; Boyd M R
The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.
Journal of medicinal chemistry 1992;35(15):2735-43.
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1992: Wu L; Smythe A M; Stinson S F; Mullendore L A; Monks A; Scudiero D A; Paull K D; Koutsoukos A D; Rubinstein L V; Boyd M R
Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening.
Cancer research 1992;52(11):3029-34.
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1992: Shoemaker R H; Smythe A M; Wu L; Balaschak M S; Boyd M R
Evaluation of metastatic human tumor burden and response to therapy in a nude mouse xenograft model using a molecular probe for repetitive human DNA sequences.
Cancer research 1992;52(10):2791-6.
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1992: Tischler M; Cardellina J H; Boyd M R; Cragg G M
Cytotoxic quassinoids from Cedronia granatensis.
Journal of natural products 1992;55(5):667-71.
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1992: Beutler J A; Cardellina J H; McMahon J B; Boyd M R; Cragg G M
Anti-HIV and cytotoxic alkaloids from Buchenavia capitata.
Journal of natural products 1992;55(2):207-13.
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1991: Manfredi K P; Blunt J W; Cardellina J H; McMahon J B; Pannell L L; Cragg G M; Boyd M R
Novel alkaloids from the tropical plant Ancistrocladus abbreviatus inhibit cell killing by HIV-1 and HIV-2.
Journal of medicinal chemistry 1991;34(12):3402-5.
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1991: Pettit G R; Herald C L; Boyd M R; Leet J E; Dufresne C; Doubek D L; Schmidt J M; Cerny R L; Hooper J N; Rützler K C
Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp.
Journal of medicinal chemistry 1991;34(11):3339-40.
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1991: Bader J P; McMahon J B; Schultz R J; Narayanan V L; Pierce J B; Harrison W A; Weislow O S; Midelfort C F; Stinson S F; Boyd M R
Oxathiin carboxanilide, a potent inhibitor of human immunodeficiency virus reproduction.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6740-4.
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1991: Shoemaker R H; Dykes D J; Plowman J; Harrison S D; Griswold D P; Abbott B J; Mayo J G; Fodstad O; Boyd M R
Practical spontaneous metastasis model for in vivo therapeutic studies using a human melanoma.
Cancer research 1991;51(11):2837-41.
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1991: Gulakowski R J; McMahon J B; Staley P G; Moran R A; Boyd M R
A semiautomated multiparameter approach for anti-HIV drug screening.
Journal of virological methods 1991;33(1-2):87-100.
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1991: Vistica D T; Skehan P; Scudiero D; Monks A; Pittman A; Boyd M R
Tetrazolium-based assays for cellular viability: a critical examination of selected parameters affecting formazan production.
Cancer research 1991;51(10):2515-20.
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1991: Ravindranath V; Boyd M R
Effect of modulators of glutathione synthesis on the hepatotoxicity of 2-methylfuran.
Biochemical pharmacology 1991;41(9):1311-8.
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1991: Alley M C; Pacula-Cox C M; Hursey M L; Rubinstein L R; Boyd M R
Morphometric and colorimetric analyses of human tumor cell line growth and drug sensitivity in soft agar culture.
Cancer research 1991;51(4):1247-56.
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1990: McLemore T L; Litterst C L; Coudert B P; Liu M C; Hubbard W C; Adelberg S; Czerwinski M; McMahon N A; Eggleston J C; Boyd M R
Metabolic activation of 4-ipomeanol in human lung, primary pulmonary carcinomas, and established human pulmonary carcinoma cell lines.
Journal of the National Cancer Institute 1990;82(17):1420-6.
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1990: Warren J T; McMahon J B; Weislow O S; Gulakowski R J; Kiser R F; Boyd M R
Interactive laser cytometric analysis of retroviral protein expression in HIV-infected lymphocytic cell lines.
AIDS research and human retroviruses 1990;6(9):1131-7.
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1990: Rubinstein L V; Shoemaker R H; Paull K D; Simon R M; Tosini S; Skehan P; Scudiero D A; Monks A; Boyd M R
Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines.
Journal of the National Cancer Institute 1990;82(13):1113-8.
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1990: Skehan P; Storeng R; Scudiero D; Monks A; McMahon J; Vistica D; Warren J T; Bokesch H; Kenney S; Boyd M R
New colorimetric cytotoxicity assay for anticancer-drug screening.
Journal of the National Cancer Institute 1990;82(13):1107-12.
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1990: Vistica D T; Scudiero D; Skehan P; Monks A; Boyd M R
New carbon dioxide-independent basal growth medium for culture of diverse tumor and nontumor cells of human and nonhuman origin.
Journal of the National Cancer Institute 1990;82(12):1055-61.
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1989: McLemore T L; Adelberg S; Czerwinski M; Hubbard W C; Yu S J; Storeng R; Wood T G; Hines R N; Boyd M R
Altered regulation of the cytochrome P4501A1 gene: novel inducer-independent gene expression in pulmonary carcinoma cell lines.
Journal of the National Cancer Institute 1989;81(23):1787-94.
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1989: Christian M C; Wittes R E; Leyland-Jones B; McLemore T L; Smith A C; Grieshaber C K; Chabner B A; Boyd M R
4-Ipomeanol: a novel investigational new drug for lung cancer.
Journal of the National Cancer Institute 1989;81(15):1133-43.
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1989: Gustafson K R; Cardellina J H; Fuller R W; Weislow O S; Kiser R F; Snader K M; Patterson G M; Boyd M R
AIDS-antiviral sulfolipids from cyanobacteria (blue-green algae).
Journal of the National Cancer Institute 1989;81(16):1254-8.
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1989: Paull K D; Shoemaker R H; Hodes L; Monks A; Scudiero D A; Rubinstein L; Plowman J; Boyd M R
Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.
Journal of the National Cancer Institute 1989;81(14):1088-92.
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1989: Weislow O S; Kiser R; Fine D L; Bader J; Shoemaker R H; Boyd M R
New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity.
Journal of the National Cancer Institute 1989;81(8):577-86.
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1989: Hubbard W C; Alley M C; Gray G N; Green K C; McLemore T L; Boyd M R
Evidence for prostanoid biosynthesis as a biochemical feature of certain subclasses of non-small cell carcinomas of the lung as determined in established cell lines derived from human lung tumors.
Cancer research 1989;49(4):826-32.
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1988: Scudiero D A; Shoemaker R H; Paull K D; Monks A; Tierney S; Nofziger T H; Currens M J; Seniff D; Boyd M R
Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.
Cancer research 1988;48(17):4827-33.
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1988: Hubbard W C; Alley M C; McLemore T L; Boyd M R
Profiles of prostaglandin biosynthesis in sixteen established cell lines derived from human lung, colon, prostate, and ovarian tumors.
Cancer research 1988;48(17):4770-5.
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1988: McLemore T L; Hubbard W C; Litterst C L; Liu M C; Miller S; McMahon N A; Eggleston J C; Boyd M R
Profiles of prostaglandin biosynthesis in normal lung and tumor tissue from lung cancer patients.
Cancer research 1988;48(11):3140-7.
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1988: McLemore T L; Eggleston J C; Shoemaker R H; Abbott B J; Bohlman M E; Liu M C; Fine D L; Mayo J G; Boyd M R
Comparison of intrapulmonary, percutaneous intrathoracic, and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice.
Cancer research 1988;48(10):2880-6.
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1988: Hubbard W C; Alley M C; McLemore T L; Boyd M R
Evidence for thromboxane biosynthesis in established cell lines derived from human lung adenocarcinomas.
Cancer research 1988;48(10):2674-7.
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1988: Alley M C; Scudiero D A; Monks A; Hursey M L; Czerwinski M J; Fine D L; Abbott B J; Mayo J G; Shoemaker R H; Boyd M R
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
Cancer research 1988;48(3):589-601.
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1988: Shoemaker R H; Monks A; Alley M C; Scudiero D A; Fine D L; McLemore T L; Abbott B J; Paull K D; Mayo J G; Boyd M R
Development of human tumor cell line panels for use in disease-oriented drug screening.
Progress in clinical and biological research 1988;276():265-86.
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1987: Fine D L; Shoemaker R; Gazdar A; Mayo J G; Fodstad O; Boyd M R; Abbott B J; Donovan P A
Metastasis models for human tumors in athymic mice: useful models for drug development.
Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc 1987;1():291-9.
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