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Antonio Villaverde
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24
Arís, Anna
19
Corchero, José Luis
16
Benito, A
16
Feliu, Jordi
15
Carrió, Mar
14
Carbonell, Xavier
11
González-Montalbán, Nuria
10
García-Fruitós, Elena
10
Ferrer-Miralles, Neus
9
Viaplana, E
7
Vera, Andrea
6
Cubarsi, R
5
Rinas, Ursula
5
Ferraz, Rosa María
4
Ramírez, E
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All Publications
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2009: Corchero José Luis; Villaverde Antonio
Biomedical applications of distally controlled magnetic nanoparticles.
Trends in biotechnology 2009;27(8):468-76.
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2009: Saccardo Paolo; Villaverde Antonio; González-Montalbán Nuria
Peptide-mediated DNA condensation for non-viral gene therapy.
Biotechnology advances 2009;27(4):432-8.
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2009: Laczka Olivier; Ferraz Rosa María; Ferrer-Miralles Neus; Villaverde Antonio; Muñoz Francesc Xavier; del Campo F Javier
Fast electrochemical detection of anti-HIV antibodies: coupling allosteric enzymes and disk microelectrode arrays.
Analytica chimica acta 2009;641(1-2):1-6.
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2009: Ferraz Rosa María; Rodríguez-Carmona Escarlata; Ferrer-Miralles Neus; Meyerhans Andreas; Villaverde Antonio
Screening HIV-1 antigenic peptides as receptors for antibodies and CD4 in allosteric nanosensors.
Journal of molecular recognition : JMR 2009;22(3):255-60.
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2009: Ferrer-Miralles Neus; Domingo-Espín Joan; Corchero José Luis; Vázquez Esther; Villaverde Antonio
Microbial factories for recombinant pharmaceuticals.
Microbial cell factories 2009;8():17.
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2009: Vázquez Esther; Ferrer-Miralles Neus; Mangues Ramón; Corchero José Luis; Schwartz Simó; Villaverde Antonio
Modular protein engineering in emerging cancer therapies.
Current pharmaceutical design 2009;15(8):893-916.
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2009: Martínez-Alonso Mónica; González-Montalbán Nuria; García-Fruitós Elena; Villaverde Antonio
Learning about protein solubility from bacterial inclusion bodies.
Microbial cell factories 2009;8():4.
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2008: Martínez-Alonso Mónica; García-Fruitós Elena; Villaverde Antonio
Yield, solubility and conformational quality of soluble proteins are not simultaneously favored in recombinant Escherichia coli.
Biotechnology and bioengineering 2008;101(6):1353-8.
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2008: Martínez-Alonso Mónica; González-Montalbán Nuria; García-Fruitós Elena; Villaverde Antonio
The Functional quality of soluble recombinant polypeptides produced in Escherichia coli is defined by a wide conformational spectrum.
Applied and environmental microbiology 2008;74(23):7431-3.
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2008: Vázquez Esther; Ferrer-Miralles Neus; Villaverde Antonio
Peptide-assisted traffic engineering for nonviral gene therapy.
Drug discovery today 2008;13(23-24):1067-74.
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2008: Ferraz Rosa María; Martínez Miguel Angel; Cubarsi Rafael; Villaverde Antonio
Antiretroviral therapy-induced functional modification of IgG4 and IgM responses in HIV-1-infected individuals screened by an allosteric biosensor.
Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 2008;13(8):817-21.
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2008: Gonzalez-Montalban Nuria; Natalello Antonino; García-Fruitós Elena; Villaverde Antonio; Doglia Silvia Maria
In situ protein folding and activation in bacterial inclusion bodies.
Biotechnology and bioengineering 2008;100(4):797-802.
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2008: Ferrer-Miralles Neus; Vázquez Esther; Villaverde Antonio
Membrane-active peptides for non-viral gene therapy: making the safest easier.
Trends in biotechnology 2008;26(5):267-75.
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2008: De Felice Maurilio; Mattanovich Diethard; Papagianni Maria; Wegrzyn Grzegorz; Villaverde Antonio
The scientific impact of microbial cell factories.
Microbial cell factories 2008;7():33.
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2008: Gasser Brigitte; Saloheimo Markku; Rinas Ursula; Dragosits Martin; Rodríguez-Carmona Escarlata; Baumann Kristin; Giuliani Maria; Parrilli Ermenegilda; Branduardi Paola; Lang Christine; Porro Danilo; Ferrer Pau; Tutino Maria Luisa; Mattanovich Diethard; Villaverde Antonio
Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview.
Microbial cell factories 2008;7():11.
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2007: García-Fruitós Elena; Martínez-Alonso Mónica; Gonzàlez-Montalbán Nuria; Valli Minoska; Mattanovich Diethard; Villaverde Antonio
Divergent genetic control of protein solubility and conformational quality in Escherichia coli.
Journal of molecular biology 2007;374(1):195-205.
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2007: Peluffo Hugo; González Pau; Arís Anna; Acarin Laia; Saura Josep; Villaverde Antoni; Castellano Bernardo; González Berta
RGD domains neuroprotect the immature brain by a glial-dependent mechanism.
Annals of neurology 2007;62(3):251-61.
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2007: Martínez-Alonso Mónica; Vera Andrea; Villaverde Antonio
Role of the chaperone DnaK in protein solubility and conformational quality in inclusion body-forming Escherichia coli cells.
FEMS microbiology letters 2007;273(2):187-95.
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2007: González-Montalbán Nuria; García-Fruitós Elena; Villaverde Antonio
Recombinant protein solubility - does more mean better?
Nature biotechnology 2007;25(7):718-20.
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2007: González-Montalbán Nuria; Villaverde Antonio; Aris Anna
Amyloid-linked cellular toxicity triggered by bacterial inclusion bodies.
Biochemical and biophysical research communications 2007;355(3):637-42.
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2007: Vera Andrea; González-Montalbán Nuria; Arís Anna; Villaverde Antonio
The conformational quality of insoluble recombinant proteins is enhanced at low growth temperatures.
Biotechnology and bioengineering 2007;96(6):1101-6.
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2007: García-Fruitós Elena; Arís Anna; Villaverde Antonio
Localization of functional polypeptides in bacterial inclusion bodies.
Applied and environmental microbiology 2007;73(1):289-94.
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2007: Villaverde Antonio; Mattanovich Diethard
Recombinant protein production in the new Millennium.
Microbial cell factories 2007;6():33.
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2006: Ferraz Rosa María; Arís Anna; Villaverde Antonio
Enhanced molecular recognition signal in allosteric biosensing by proper substrate selection.
Biotechnology and bioengineering 2006;94(1):193-9.
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2006: Ferraz Rosa María; Arís Anna; Martínez Miguel Angel; Villaverde Antonio
High-throughput, functional screening of the anti-HIV-1 humoral response by an enzymatic nanosensor.
Molecular immunology 2006;43(13):2119-23.
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2006: Ventura Salvador; Villaverde Antonio
Protein quality in bacterial inclusion bodies.
Trends in biotechnology 2006;24(4):179-85.
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2006: González-Montalbán Nuria; García-Fruitós Elena; Ventura Salvador; Arís Anna; Villaverde Antonio
The chaperone DnaK controls the fractioning of functional protein between soluble and insoluble cell fractions in inclusion body-forming cells.
Microbial cell factories 2006;5():26.
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2006: Peluffo Hugo; Acarin Laia; Arís Anna; González Pau; Villaverde Antoni; Castellano Bernardo; González Berta
Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector.
BMC neuroscience 2006;7():35.
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2006: Ferraz Rosa María; Vera Andrea; Arís Anna; Villaverde Antonio
Insertional protein engineering for analytical molecular sensing.
Microbial cell factories 2006;5():15.
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2005: García-Fruitós Elena; González-Montalbán Nuria; Morell Montse; Vera Andrea; Ferraz Rosa María; Arís Anna; Ventura Salvador; Villaverde Antonio
Aggregation as bacterial inclusion bodies does not imply inactivation of enzymes and fluorescent proteins.
Microbial cell factories 2005;4():27.
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2005: González-Montalbán Nuria; Carrió M Mar; Cuatrecasas Sergi; Arís Anna; Villaverde Antonio
Bacterial inclusion bodies are cytotoxic in vivo in absence of functional chaperones DnaK or GroEL.
Journal of biotechnology 2005;118(4):406-12.
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2005: Vera Andrea; Arís Anna; Carrió Mar; González-Montalbán Nuria; Villaverde Antonio
Lon and ClpP proteases participate in the physiological disintegration of bacterial inclusion bodies.
Journal of biotechnology 2005;119(2):163-71.
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2005: Cubarsi R; Carrió M M; Villaverde A
A mathematical approach to molecular organization and proteolytic disintegration of bacterial inclusion bodies.
Mathematical medicine and biology : a journal of the IMA 2005;22(3):209-26.
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2005: García-Fruitós Elena; Carrió M Mar; Arís Anna; Villaverde Antonio
Folding of a misfolding-prone beta-galactosidase in absence of DnaK.
Biotechnology and bioengineering 2005;90(7):869-75.
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2005: Carrió M Mar; Villaverde Antonio
Localization of chaperones DnaK and GroEL in bacterial inclusion bodies.
Journal of bacteriology 2005;187(10):3599-601.
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2005: Carrió Mar; González-Montalbán Nuria; Vera Andrea; Villaverde Antonio; Ventura Salvador
Amyloid-like properties of bacterial inclusion bodies.
Journal of molecular biology 2005;347(5):1025-37.
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2005: Vera Andrea; Arís Anna; Daura Xavier; Martínez Miguel Angel; Villaverde Antonio
Engineering the E. coli beta-galactosidase for the screening of antiviral protease inhibitors.
Biochemical and biophysical research communications 2005;329(2):453-6.
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2004: Arís Anna; Villaverde Antonio
Modular protein engineering for non-viral gene therapy.
Trends in biotechnology 2004;22(7):371-7.
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2004: Petersson Lisa; Carrió M Mar; Vera Andrea; Villaverde Antonio
The impact of dnaKJ overexpression on recombinant protein solubility results from antagonistic effects on the control of protein quality.
Biotechnology letters 2004;26(7):595-601.
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2004: Ferraz Rosa M; Arís Anna; Villaverde Antonio
Profiling the allosteric response of an engineered beta-galactosidase to its effector, anti-HIV antibody.
Biochemical and biophysical research communications 2004;314(3):854-60.
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2003: Villaverde Antonio
Allosteric enzymes as biosensors for molecular diagnosis.
FEBS letters 2003;554(1-2):169-72.
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2003: Villaverde Antonio; Carrió M Mar
Protein aggregation in recombinant bacteria: biological role of inclusion bodies.
Biotechnology letters 2003;25(17):1385-95.
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2003: Peluffo H; Arís A; Acarin L; González B; Villaverde A; Castellano B
Nonviral gene delivery to the central nervous system based on a novel integrin-targeting multifunctional protein.
Human gene therapy 2003;14(13):1215-23.
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2003: Arís Anna; Villaverde Antonio
Engineering nuclear localization signals in modular protein vehicles for gene therapy.
Biochemical and biophysical research communications 2003;304(4):625-31.
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2003: Carrió M Mar; Villaverde Antonio
Role of molecular chaperones in inclusion body formation.
FEBS letters 2003;537(1-3):215-21.
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2003: Alcalá Pilar; Ferrer-Miralles Neus; Villaverde Antonio
Engineering of Escherichia coli beta-galactosidase for solvent display of a functional scFv antibody fragment.
FEBS letters 2003;533(1-3):115-8.
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2002: Carrió M M; Villaverde A
Construction and deconstruction of bacterial inclusion bodies.
Journal of biotechnology 2002;96(1):3-12.
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2002: Medina Manel G; Carbonell Xavier; Villaverde Antonio
Connection between gene dosage and protein stability revealed by a high-yield production of recombinant proteins in an E. coli LexA1(Ind-) background.
Biotechnology and bioengineering 2002;78(7):722-30.
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2002: Feliu Jordi X; Ferrer-Miralles Neus; Blanco Esther; Cazorla Daniel; Sobrino Francisco; Villaverde Antonio
Enhanced response to antibody binding in engineered beta-galactosidase enzymatic sensors.
Biochimica et biophysica acta 2002;1596(2):212-24.
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2002: Carbonell Xavier; Corchero José Luis; Cubarsí Rafael; Vila Pau; Villaverde Antonio
Control of Escherichia coli growth rate through cell density.
Microbiological research 2002;157(4):257-65.
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2001: Ferrer-Miralles N; Feliu J X; Vandevuer S; Müller A; Cabrera-Crespo J; Ortmans I; Hoffmann F; Cazorla D; Rinas U; Prévost M; Villaverde A
Engineering regulable Escherichia coli beta-galactosidases as biosensors for anti-HIV antibody detection in human sera.
The Journal of biological chemistry 2001;276(43):40087-95.
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2001: Alcalá P; Feliu J X; Arís A; Villaverde A
Efficient accommodation of recombinant, foot-and-mouth disease virus RGD peptides to cell-surface integrins.
Biochemical and biophysical research communications 2001;285(2):201-6.
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2001: Cubarsí R; Carrió M M; Villaverde A
In situ proteolytic digestion of inclusion body polypeptides occurs as a cascade process.
Biochemical and biophysical research communications 2001;282(2):436-41.
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2001: Cazorla D; Feliu J X; Villaverde A
Variable specific activity of Escherichia coli beta-galactosidase in bacterial cells.
Biotechnology and bioengineering 2001;72(3):255-60.
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2001: Carrió M M; Villaverde A
Protein aggregation as bacterial inclusion bodies is reversible.
FEBS letters 2001;489(1):29-33.
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2001: Ramirez E; Carbonell X; Villaverde A
Phage spread dynamics in clonal bacterial populations is depending on features of the founder cell.
Microbiological research 2001;156(1):35-40.
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2001: Corchero J L; Cubarsí R; Vila P; Arís A; Villaverde A
Cell lysis in Escherichia coli cultures stimulates growth and biosynthesis of recombinant proteins in surviving cells.
Microbiological research 2001;156(1):13-8.
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2000: Arís A; Villaverde A
Molecular organization of protein-DNA complexes for cell-targeted DNA delivery.
Biochemical and biophysical research communications 2000;278(2):455-61.
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2000: Ferrer-Miralles N; Feliu J X; Villaverde A
Molecular mechanisms for antibody-mediated modulation of peptide-displaying enzyme sensors.
Biochemical and biophysical research communications 2000;275(2):360-4.
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2000: Arís A; Feliu J X; Knight A; Coutelle C; Villaverde A
Exploiting viral cell-targeting abilities in a single polypeptide, non-infectious, recombinant vehicle for integrin-mediated DNA delivery and gene expression.
Biotechnology and bioengineering 2000;68(6):689-96.
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2000: Feliu J X; Carbonell X; Villaverde A
Successful mimicry of a complex viral antigen by multiple peptide insertions in a carrier protein.
FEBS letters 2000;474(1):87-92.
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2000: Carrió M M; Cubarsi R; Villaverde A
Fine architecture of bacterial inclusion bodies.
FEBS letters 2000;471(1):7-11.
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1999: Carrió M M; Corchero J L; Villaverde A
Proteolytic digestion of bacterial inclusion body proteins during dynamic transition between soluble and insoluble forms.
Biochimica et biophysica acta 1999;1434(1):170-6.
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1999: Ramírez E; Mas J M; Carbonell X; Avilés F X; Villaverde A
Detection of molecular interactions by using a new peptide-displaying bacteriophage biosensor.
Biochemical and biophysical research communications 1999;262(3):801-5.
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1999: Corchero J L; Villaverde A
Tolerance of Escherichia coli beta-galactosidase C-terminus to different-sized fusions.
Biotechnology and bioengineering 1999;64(6):644-9.
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1999: Hoffmann F; Arís A; Carbonell X; Rohde M; Corchero J L; Rinas U; Villaverde A
Heat-inactivation of plasmid-encoded CI857 repressor induces gene expression from Ind- lambda prophage in recombinant Escherichia coli.
FEMS microbiology letters 1999;177(2):327-34.
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1999: Ramírez E; Schmidt M; Rinas U; Villaverde A
RecA-dependent viral burst in bacterial colonies during the entry into stationary phase.
FEMS microbiology letters 1999;170(2):313-7.
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1999: Schmidt M; Viaplana E; Hoffmann F; Marten S; Villaverde A; Rinas U
Secretion-dependent proteolysis of heterologous protein by recombinant Escherichia coli is connected to an increased activity of the energy-generating dissimilatory pathway.
Biotechnology and bioengineering 1999;66(1):61-7.
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1998: Arís A; Corchero J L; Benito A; Carbonell X; Viaplana E; Villaverde A
The expression of recombinant genes from bacteriophage lambda strong promoters triggers the SOS response in Escherichia coli.
Biotechnology and bioengineering 1998;60(5):551-9.
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1998: Carrió M M; Corchero J L; Villaverde A
Dynamics of in vivo protein aggregation: building inclusion bodies in recombinant bacteria.
FEMS microbiology letters 1998;169(1):9-15.
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1998: Feliu J X; Ramírez E; Villaverde A
Distinct mechanisms of antibody-mediated enzymatic reactivation in beta-galactosidase molecular sensors.
FEBS letters 1998;438(3):267-71.
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1998: Feliu J X; Benito A; Oliva B; Avilés F X; Villaverde A
Conformational flexibility in a highly mobile protein loop of foot-and-mouth disease virus: distinct structural requirements for integrin and antibody binding.
Journal of molecular biology 1998;283(2):331-8.
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1998: Cubarsi R; Corchero J L; Vila P; Villaverde A
Numerical techniques and mathematical modelling for CI857-controlled gene expression and cell growth in recombinant E. coli.
IMA journal of mathematics applied in medicine and biology 1998;15(3):257-78.
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1998: Villaverde A; Feliu J X; Arís A; Harbottle R P; Benito A; Coutelle C
A cell adhesion peptide from foot-and-mouth disease virus can direct cell targeted delivery of a functional enzyme.
Biotechnology and bioengineering 1998;59(3):294-301.
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1998: Feliu J X; Villaverde A
Engineering of solvent-exposed loops in Escherichia coli beta-galactosidase.
FEBS letters 1998;434(1-2):23-7.
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1998: Carbonell X; Villaverde A
Unfolding of bacteriophage P22 tailspike protein: enhanced thermal stability of an N-terminal fusion mutant.
FEBS letters 1998;432(3):228-30.
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1998: Carbonell X; Feliu J X; Benito A; Villaverde A
Display-induced antigenic variation in recombinant peptides.
Biochemical and biophysical research communications 1998;248(3):773-7.
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1998: Corchero J L; Villaverde A
Plasmid maintenance in Escherichia coli recombinant cultures is dramatically, steadily, and specifically influenced by features of the encoded proteins.
Biotechnology and bioengineering 1998;58(6):625-32.
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1998: Feliu J X; Cubarsi R; Villaverde A
Optimized release of recombinant proteins by ultrasonication of E. coli cells.
Biotechnology and bioengineering 1998;58(5):536-40.
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1998: Carbonell X; Villaverde A
Insertional mutagenesis in the tailspike protein of bacteriophage P22.
Biochemical and biophysical research communications 1998;244(2):428-33.
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1997: Viaplana E; Feliu J X; Corchero J L; Villaverde A
Reversible activation of a cryptic cleavage site within E. coli beta-galactosidase in beta-galactosidase fusion proteins.
Biochimica et biophysica acta 1997;1343(2):221-6.
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1997: Ramírez E; Villaverde A
Viral spread within ageing bacterial populations.
Gene 1997;202(1-2):147-9.
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1997: Corchero J L; Cubarsí R; Enfors S; Villaverde A
Limited in vivo proteolysis of aggregated proteins.
Biochemical and biophysical research communications 1997;237(2):325-30.
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1997: Viaplana E; Plana J; Villaverde A
Antigenicity of VP60 structural protein of rabbit haemorrhagic disease virus.
Archives of virology 1997;142(9):1843-8.
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1996: Villaverde A; Feliu J X; Harbottle R P; Benito A; Coutelle C
A recombinant, arginine-glycine-aspartic acid (RGD) motif from foot-and-mouth disease virus binds mammalian cells through vitronectin and, to a lower extent, fibronectin receptors.
Gene 1996;180(1-2):101-6.
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1996: Carbonell X; Benito A; Villaverde A
Converging antigenic structure of a recombinant viral peptide displayed on different frameworks of carrier proteins.
FEBS letters 1996;397(2-3):169-72.
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1996: Corchero J L; Villaverde A
Antigenicity of a viral peptide displayed on beta-galactosidase fusion proteins is influenced by the presence of the homologous partner protein.
FEMS microbiology letters 1996;145(1):77-82.
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1996: Carbonell X; Villaverde A
Peptide display on functional tailspike protein of bacteriophage P22.
Gene 1996;176(1-2):225-9.
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1996: Viaplana E; Villaverde A
Polylinker-encoded peptides can confer toxicity to recombinant proteins produced in Escherichia coli.
Biotechnology progress 1996;12(5):723-7.
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1996: Benito A; Feliu J X; Villaverde A
Beta-galactosidase enzymatic activity as a molecular probe to detect specific antibodies.
The Journal of biological chemistry 1996;271(35):21251-6.
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1996: Corchero J L; Viaplana E; Benito A; Villaverde A
The position of the heterologous domain can influence the solubility and proteolysis of beta-galactosidase fusion proteins in E. coli.
Journal of biotechnology 1996;48(3):191-200.
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1996: Viaplana E; Villaverde A
Microheterogeneity of p60 capsid protein and the encoding gene among contemporary isolates of rabbit hemorrhagic disease virus.
Virus genes 1996;12(2):189-92.
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1995: Benito A; Mateu M G; Villaverde A
Improved mimicry of a foot-and-mouth disease virus antigenic site by a viral peptide displayed on beta-galactosidase surface.
Bio/technology (Nature Publishing Company) 1995;13(8):801-4.
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1995: Benito A; Viaplana E; Corchero J L; Carbonell X; Villaverde A
A recombinant foot-and-mouth disease virus antigen inhibits DNA replication and triggers the SOS response in Escherichia coli.
FEMS microbiology letters 1995;129(2-3):157-62.
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1995: Corchero J L; Carbonell X; Benito A; Villaverde A
Mitomycin C stimulates thermally induced recombinant gene expression in Escherichia coli MC strains.
Applied microbiology and biotechnology 1995;42(6):890-4.
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1994: Vila P; Corchero J L; Benito A; Villaverde A
Ammonium-mediated reduction of plasmid copy number and recombinant gene expression in Escherichia coli.
Biotechnology progress 1994;10(6):648-51.
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1994: Benito A; Villaverde A
Insertion of a 27 amino acid viral peptide in different zones of Escherichia coli beta-galactosidase: effects on the enzyme activity.
FEMS microbiology letters 1994;123(1-2):107-12.
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1993: Villaverde A; Benito A; Viaplana E; Cubarsi R
Fine regulation of cI857-controlled gene expression in continuous culture of recombinant Escherichia coli by temperature.
Applied and environmental microbiology 1993;59(10):3485-7.
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1993: Benito A; Vidal M; Villaverde A
Enhanced production of pL-controlled recombinant proteins and plasmid stability in Escherichia coli RecA+ strains.
Journal of biotechnology 1993;29(3):299-306.
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1993: Benito A; Valero F; Lafuente J; Vidal M; Cairo J; Solà C; Villaverde A
Uses of beta-galactosidase tag in on-line monitoring production of fusion proteins and gene expression in Escherichia coli.
Enzyme and microbial technology 1993;15(1):66-71.
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1992: Villaverde A; Barbé J
SOS system induction in Escherichia coli cells with distinct levels of ribonucleotide reductase activity.
Mutation research 1992;281(2):137-41.
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1991: Vidal M; Cairó J; Mateu M G; Villaverde A
Molecular cloning and expression of the VP1 gene of foot-and-mouth disease virus C1 in E. coli: effect on bacterial cell viability.
Applied microbiology and biotechnology 1991;35(6):788-92.
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1988: Villaverde A; Gibert I; Barbé J
Evidence for a specific regulation of recA gene transcription in Escherichia coli.
Mutation research 1988;199(1):123-30.
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1987: Barbé J; Villaverde A; Guerrero R
Induction of the SOS response by hydroxyurea in Escherichia coli K12.
Mutation research 1987;192(2):105-8.
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1986: Barbé J; Villaverde A; Cairo J; Guerrero R
ATP hydrolysis during SOS induction in Escherichia coli.
Journal of bacteriology 1986;167(3):1055-7.
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