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BJ Vilner

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TOP 3
BJ Vilner; Wayne D Bowen
Modulation of cellular calcium by sigma-2 receptors: release from intracellular stores in human SK-N-SH neuroblastoma cells.
Blandine Kedjouar; S Daunes; BJ Vilner; Wayne D Bowen; A Klaebe; Jean-Charles Faye; Marc Poirot
Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor.
Stephen M Husbands; Sari Izenwasser; Theresa A Kopajtic; Wayne D Bowen; BJ Vilner; Jonathan L Katz; Amy Hauck Newman
Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.

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All Publications

2000: BJ Vilner; Wayne D Bowen
Modulation of cellular calcium by sigma-2 receptors: release from intracellular stores in human SK-N-SH neuroblastoma cells.
The Journal of pharmacology and experimental therapeutics 2000;292(3):900-11.
1999: Blandine Kedjouar; S Daunes; BJ Vilner; Wayne D Bowen; A Klaebe; Jean-Charles Faye; Marc Poirot
Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor.
Biochemical pharmacology 1999;58(12):1927-39.
1999: Stephen M Husbands; Sari Izenwasser; Theresa A Kopajtic; Wayne D Bowen; BJ Vilner; Jonathan L Katz; Amy Hauck Newman
Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.
Journal of medicinal chemistry 1999;42(21):4446-55.
1999: CS John; BJ Vilner; BC Geyer; T Moody; Wayne D Bowen
Targeting sigma receptor-binding benzamides as in vivo diagnostic and therapeutic agents for human prostate tumors.
Cancer research 1999;59(18):4578-83.
1999: CS John; Wayne D Bowen; S J Fisher; BB Lim; BC Geyer; BJ Vilner; Richard L Wahl
Synthesis, in vitro pharmacologic characterization, and preclinical evaluation of N-[2-(1'-piperidinyl)ethyl]-3-[125I]iodo-4-methoxybenzamide (P[125I]MBA) for imaging breast cancer.
Nuclear medicine and biology 1999;26(4):377-82.
1998: CS John; BB Lim; BJ Vilner; BC Geyer; Wayne D Bowen
Substituted halogenated arylsulfonamides: a new class of sigma receptor binding tumor imaging agents.
Journal of medicinal chemistry 1998;41(14):2445-50.
1997: Stephen M Husbands; Sari Izenwasser; RJ Loeloff; Jonathan L Katz; Wayne D Bowen; BJ Vilner; Amy Hauck Newman
Isothiocyanate derivatives of 9-[3-(cis-3,5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole): irreversible ligands for the dopamine transporter.
Journal of medicinal chemistry 1997;40(26):4340-46.
1997: CS John; BB Lim; BC Geyer; BJ Vilner; Wayne D Bowen
99mTc-labeled sigma-receptor-binding complex: synthesis, characterization, and specific binding to human ductal breast carcinoma (T47D) cells.
Bioconjugate chemistry 1997;8(3):304-9.
1996: CS John; M E Gulden; BJ Vilner; Wayne D Bowen
Synthesis, in vitro validation and in vivo pharmacokinetics of [125I]N-[2-(4-iodophenyl)ethyl]-N-methyl-2-(1-piperidinyl) ethylamine: a high-affinity ligand for imaging sigma receptor positive tumors.
Nuclear medicine and biology 1996;23(6):761-6.
1995: C M Bertha; BJ Vilner; M V Mattson; Wayne D Bowen; K Becketts; HAN XU; Richard B Rothman; Judith L Flippen-Anderson; Kenner C Rice
(E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype.
Journal of medicinal chemistry 1995;38(24):4776-85.
1995: CS John; BJ Vilner; M E Gulden; S M N Efange; R B Langason; Terry W Moody; Wayne D Bowen
Synthesis and pharmacological characterization of 4-[125I]-N-(N-benzylpiperidin-4-yl)-4-iodobenzamide: a high affinity sigma receptor ligand for potential imaging of breast cancer.
Cancer research 1995;55(14):3022-7.
1995: Wayne D Bowen; BJ Vilner; Wanda Williams; C M Bertha; Martin E Kuehne; Arthur E Jacobson
Ibogaine and its congeners are sigma 2 receptor-selective ligands with moderate affinity.
European journal of pharmacology 1995;279(1):R1-3.
1995: Wayne D Bowen; C M Bertha; BJ Vilner; Kenner C Rice
CB-64D and CB-184: ligands with high sigma 2 receptor affinity and subtype selectivity.
European journal of pharmacology 1995;278(3):257-60.
1995: BJ Vilner; CS John; Wayne D Bowen
Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines.
Cancer research 1995;55(2):408-13.
1995: BJ Vilner; B R de Costa; Wayne D Bowen
Cytotoxic effects of sigma ligands: sigma receptor-mediated alterations in cellular morphology and viability.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(1 Pt 1):117-34.
1994: CS John; BJ Vilner; Wayne D Bowen
Synthesis and characterization of [125I]-N-(N-benzylpiperidin-4-yl)-4- iodobenzamide, a new sigma receptor radiopharmaceutical: high-affinity binding to MCF-7 breast tumor cells.
Journal of medicinal chemistry 1994;37(12):1737-9.
1993: CS John; Wayne D Bowen; T Saga; S Kinuya; BJ Vilner; J Baumgold; Chang H Paik; Richard C Reba; R D Neumann; V M Varma
A malignant melanoma imaging agent: synthesis, characterization, in vitro binding and biodistribution of iodine-125-(2-piperidinylaminoethyl)4-iodobenzamide.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(12):2169-75.
1993: BJ Vilner; Wayne D Bowen
Sigma receptor-active neuroleptics are cytotoxic to C6 glioma cells in culture.
European journal of pharmacology 1993;244(2):199-201.