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E Viñuela

Research Profile

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Germán Andrés; Ramón García-Escudero; E Viñuela; María L Salas; Javier M Rodríguez
African swine fever virus structural protein pE120R is essential for virus transport from assembly sites to plasma membrane but not for infectivity.
Ramón García-Escudero; E Viñuela
Structure of African swine fever virus late promoters: requirement of a TATA sequence at the initiation region.
I Galindo; F Almazán; María J Bustos; E Viñuela; Angel L Carrascosa
African swine fever virus EP153R open reading frame encodes a glycoprotein involved in the hemadsorption of infected cells.

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All Publications

2001: Germán Andrés; Ramón García-Escudero; E Viñuela; María L Salas; Javier M Rodríguez
African swine fever virus structural protein pE120R is essential for virus transport from assembly sites to plasma membrane but not for infectivity.
Journal of virology 2001;75(15):6758-68.
2000: Ramón García-Escudero; E Viñuela
Structure of African swine fever virus late promoters: requirement of a TATA sequence at the initiation region.
Journal of virology 2000;74(17):8176-82.
2000: I Galindo; F Almazán; María J Bustos; E Viñuela; Angel L Carrascosa
African swine fever virus EP153R open reading frame encodes a glycoprotein involved in the hemadsorption of infected cells.
Virology 2000;266(2):340-51.
2000: I Galindo; E Viñuela; Angel L Carrascosa
Characterization of the african swine fever virus protein p49: a new late structural polypeptide.
The Journal of general virology 2000;81(Pt 1):59-65.
1999: M Oliveros; Ramón García-Escudero; Alí Alejo; E Viñuela; María L Salas; José Salas
African swine fever virus dUTPase is a highly specific enzyme required for efficient replication in swine macrophages.
Journal of virology 1999;73(11):8934-43.
1999: Alí Alejo; Germán Andrés; E Viñuela; María L Salas
The African swine fever virus prenyltransferase is an integral membrane trans-geranylgeranyl-diphosphate synthase.
The Journal of biological chemistry 1999;274(25):18033-9.
1999: G Rojo; R García-Beato; E Viñuela; María L Salas; José Salas
Replication of African swine fever virus DNA in infected cells.
Virology 1999;257(2):524-36.
1999: Angel L Carrascosa; María J Bustos; I Galindo; E Viñuela
Virus-specific cell receptors are necessary, but not sufficient, to confer cell susceptibility to African swine fever virus.
Archives of virology 1999;144(7):1309-21.
1998: E Baixeras; A Cebrián; Juan Pablo Albar; José Salas; C Martínez-A; E Viñuela; Yolanda Revilla
Vaccinia virus-induced apoptosis in immature B lymphocytes: role of cellular Bcl-2.
Virus research 1998;58(1-2):107-13.
1998: Germán Andrés; Ramón García-Escudero; Carmen Simón-Mateo; E Viñuela
African swine fever virus is enveloped by a two-membraned collapsed cisterna derived from the endoplasmic reticulum.
Journal of virology 1998;72(11):8988-9001.
1998: G Rojo; Margarita Chamorro; María L Salas; E Viñuela; José M Cuezva; José Salas
Migration of mitochondria to viral assembly sites in African swine fever virus-infected cells.
Journal of virology 1998;72(9):7583-8.
1998: Ramón García-Escudero; Germán Andrés; F Almazán; E Viñuela
Inducible gene expression from African swine fever virus recombinants: analysis of the major capsid protein p72.
Journal of virology 1998;72(4):3185-95.
1998: Yolanda Revilla; M Callejo; Javier M Rodríguez; E Culebras; María L Nogal; María L Salas; E Viñuela; Manuel Fresno
Inhibition of nuclear factor kappaB activation by a virus-encoded IkappaB-like protein.
The Journal of biological chemistry 1998;273(9):5405-11.
1997: M Oliveros; R J Yáñez; María L Salas; José Salas; E Viñuela; Luis Blanco
Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair.
The Journal of biological chemistry 1997;272(49):30899-910.
1997: Carmen Simón-Mateo; Germán Andrés; F Almazán; E Viñuela
Proteolytic processing in African swine fever virus: evidence for a new structural polyprotein, pp62.
Journal of virology 1997;71(8):5799-804.
1997: I Galindo; E Viñuela; Angel L Carrascosa
Protein cell receptors mediate the saturable interaction of African swine fever virus attachment protein p12 with the surface of permissive cells.
Virus research 1997;49(2):193-204.
1997: Fernando Alonso; Javier Domínguez; E Viñuela; Yolanda Revilla
African swine fever virus-specific cytotoxic T lymphocytes recognize the 32 kDa immediate early protein (vp32).
Virus research 1997;49(2):123-30.
1997: Alí Alejo; R J Yáñez; Javier M Rodríguez; E Viñuela; María L Salas
African swine fever virus trans-prenyltransferase.
The Journal of biological chemistry 1997;272(14):9417-23.
1997: L Martinez-Pomares; C Simon-Mateo; C Lopez-Otin; E Viñuela
Characterization of the African swine fever virus structural protein p14.5: a DNA binding protein.
Virology 1997;229(1):201-11.
1997: Germán Andrés; Carmen Simón-Mateo; E Viñuela
Assembly of African swine fever virus: role of polyprotein pp220.
Journal of virology 1997;71(3):2331-41.
1997: Yolanda Revilla; A Cebrián; E Baixerás; C Martínez; E Viñuela; María L Salas
Inhibition of apoptosis by the African swine fever virus Bcl-2 homologue: role of the BH1 domain.
Virology 1997;228(2):400-4.
1996: Javier M Rodríguez; M L Salas; E Viñuela
Intermediate class of mRNAs in African swine fever virus.
Journal of virology 1996;70(12):8584-9.
1995: Matilde chacon; F Almazán; M L Nogal; E Viñuela; J F Rodríguez
The African swine fever virus IAP homolog is a late structural polypeptide.
Virology 1995;214(2):670-4.
1995: Angel L Carrascosa; Isabel Sastre; E Viñuela
Production and purification of recombinant African swine fever virus attachment protein p12.
Journal of biotechnology 1995;40(2):73-86.
1995: R García; F Almazán; Javier M Rodríguez; M Alonso; E Viñuela; J F Rodríguez
Vectors for the genetic manipulation of African swine fever virus.
Journal of biotechnology 1995;40(2):121-31.
1995: R J Yáñez; Javier M Rodríguez; M L Nogal; Luis Yuste; C Enríquez; J F Rodriguez; E Viñuela
Analysis of the complete nucleotide sequence of African swine fever virus.
Virology 1995;208(1):249-78.
1995: F Almazán; J R Murguía; Javier M Rodríguez; I de la Vega; E Viñuela
A set of African swine fever virus tandem repeats shares similarities with SAR-like sequences.
The Journal of general virology 1995;76 ( Pt 4)():729-40.
1995: Carmen Simón-Mateo; J M Freije; Germán Andrés; Carlos López-Otín; E Viñuela
Mapping and sequence of the gene encoding protein p17, a major African swine fever virus structural protein.
Virology 1995;206(2):1140-4.
1995: C J Villeda; jose carlos Gómez-Villamandos; S M Williams; J Hervás; PJ Wilkinson; E Viñuela
The role of fibrinolysis in the pathogenesis of the haemorrhagic syndrome produced by virulent isolates of African swine fever virus.
Thrombosis and haemostasis 1995;73(1):112-7.
1994: Yolanda Revilla; L Pena; F Mampaso; E Viñuela; C Martinez-Alonso
Swine-reconstituted SCID mice as a model for African swine fever virus infection.
The Journal of general virology 1994;75 ( Pt 8)():1983-8.
1994: I de la Vega; A González; R Blasco; Victor Calvo; E Viñuela
Nucleotide sequence and variability of the inverted terminal repetitions of African swine fever virus DNA.
Virology 1994;201(1):152-6.
1994: J M Rodriguez; R J Yañez; R Pan; J F Rodriguez; M L Salas; E Viñuela
Multigene families in African swine fever virus: family 505.
Journal of virology 1994;68(4):2746-51.
1993: Javier M Rodríguez; R J Yáñez; J F Rodríguez; E Viñuela; M L Salas
The DNA polymerase-encoding gene of African swine fever virus: sequence and transcriptional analysis.
Gene 1993;136(1-2):103-10.
1993: R J Yáñez; Javier M Rodríguez; M Boursnell; J F Rodríguez; E Viñuela
Two putative African swine fever virus helicases similar to yeast 'DEAH' pre-mRNA processing proteins and vaccinia virus ATPases D11L and D6R.
Gene 1993;134(2):161-74.
1993: A Alcamí; A Angulo; E Viñuela
Mapping and sequence of the gene encoding the African swine fever virion protein of M(r) 11500.
The Journal of general virology 1993;74 ( Pt 11)():2317-24.
1993: J M Freije; S Laín; E Viñuela; Carlos López-Otín
Nucleotide sequence of a nucleoside triphosphate phosphohydrolase gene from African swine fever virus.
Virus research 1993;30(1):63-72.
1993: A Angulo; E Viñuela; A Alcamí
Inhibition of African swine fever virus binding and infectivity by purified recombinant virus attachment protein p12.
Journal of virology 1993;67(9):5463-71.
1993: Javier M Rodríguez; R J Yáñez; F Almazán; E Viñuela; J F Rodriguez
African swine fever virus encodes a CD2 homolog responsible for the adhesion of erythrocytes to infected cells.
Journal of virology 1993;67(9):5312-20.
1993: R J Yáñez; Javier M Rodríguez; J F Rodríguez; M L Salas; E Viñuela
African swine fever virus thymidylate kinase gene: sequence and transcriptional mapping.
The Journal of general virology 1993;74 ( Pt 8)():1633-8.
1993: Carmen Simón-Mateo; Germán Andrés; E Viñuela
Polyprotein processing in African swine fever virus: a novel gene expression strategy for a DNA virus.
The EMBO journal 1993;12(7):2977-87.
1993: R J Yáñez; M Boursnell; M L Nogal; Luis Yuste; E Viñuela
African swine fever virus encodes two genes which share significant homology with the two largest subunits of DNA-dependent RNA polymerases.
Nucleic acids research 1993;21(10):2423-7.
1993: Germán Andrés; Carmen Simón-Mateo; E Viñuela
Characterization of two African swine fever virus 220-kDa proteins: a precursor of the major structural protein p150 and an oligomer of phosphoprotein p32.
Virology 1993;194(1):284-93.
1993: F J Prados; E Viñuela; A Alcamí
Sequence and characterization of the major early phosphoprotein p32 of African swine fever virus.
Journal of virology 1993;67(5):2475-85.
1993: R J Yáñez; E Viñuela
African swine fever virus encodes a DNA ligase.
Virology 1993;193(1):531-6.
1993: L Pena; R J Yáñez; Yolanda Revilla; E Viñuela; M L Salas
African swine fever virus guanylyltransferase.
Virology 1993;193(1):319-28.
1993: Angel L Carrascosa; I Saastre; P González; E Viñuela
Localization of the African swine fever virus attachment protein P12 in the virus particle by immunoelectron microscopy.
Virology 1993;193(1):460-5.
1993: J M Freije; M Muñoz; E Viñuela; Carlos López-Otín
High-level expression in Escherichia coli of the gene coding for the major structural protein (p72) of African swine fever virus.
Gene 1993;123(2):259-62.
1993: M Muñoz; J M Freije; M L Salas; E Viñuela; Carlos López-Otín
Structure and expression in E. coli of the gene coding for protein p10 of African swine fever virus.
Archives of virology 1993;130(1-2):93-107.
1993: C J Villeda; S M Williams; PJ Wilkinson; E Viñuela
Haemostatic abnormalities in African swine fever a comparison of two virus strains of different virulence (Dominican Republic '78 and Malta '78).
Archives of virology 1993;130(1-2):71-83.
1993: F Almazán; Javier M Rodríguez; A Angulo; E Viñuela; J F Rodriguez
Transcriptional mapping of a late gene coding for the p12 attachment protein of African swine fever virus.
Journal of virology 1993;67(1):553-6.
1993: C J Villeda; S M Williams; PJ Wilkinson; E Viñuela
Consumption coagulopathy associated with shock in acute African swine fever.
Archives of virology 1993;133(3-4):467-75.
1993: A Angulo; A Alcamí; E Viñuela
Virus-host interactions in African swine fever: the attachment to cellular receptors.
Archives of virology. Supplementum 1993;7():169-83.
1992: F Almazán; Ricardo Pérez-Sánchez; Germán Andrés; R Pérez; E Viñuela; J F Rodriguez
Transcriptional analysis of multigene family 110 of African swine fever virus.
Journal of virology 1992;66(11):6655-67.
1992: R García-Beato; M L Salas; E Viñuela; José Salas
Role of the host cell nucleus in the replication of African swine fever virus DNA.
Virology 1992;188(2):637-49.
1992: A Angulo; E Viñuela; A Alcamí
Comparison of the sequence of the gene encoding African swine fever virus attachment protein p12 from field virus isolates and viruses passaged in tissue culture.
Journal of virology 1992;66(6):3869-72.
1992: A Alcamí; A Angulo; Carlos López-Otín; M Muñoz; J M Freije; Angel L Carrascosa; E Viñuela
Amino acid sequence and structural properties of protein p12, an African swine fever virus attachment protein.
Journal of virology 1992;66(6):3860-8.
1992: R García-Beato; J M Freije; Carlos López-Otín; R Blasco; E Viñuela; M L Salas
A gene homologous to topoisomerase II in African swine fever virus.
Virology 1992;188(2):938-47.
1992: Javier M Rodríguez; F Almazán; E Viñuela; J F Rodriguez
Genetic manipulation of African swine fever virus: construction of recombinant viruses expressing the beta-galactosidase gene.
Virology 1992;188(1):67-76.
1992: Yolanda Revilla; L Pena; E Viñuela
Interferon-gamma production by African swine fever virus-specific lymphocytes.
Scandinavian journal of immunology 1992;35(2):225-30.
1992: J M Rodriguez; M L Salas; E Viñuela
Genes homologous to ubiquitin-conjugating proteins and eukaryotic transcription factor SII in African swine fever virus.
Virology 1992;186(1):40-52.
1991: B Aguado; E Viñuela; A Alcamí
African swine fever virus fatty acid acylated proteins.
Virology 1991;185(2):942-5.
1991: J M Alonso; J Rodriguez; E Viñuela; Guido Kroemer; Carlos Martínez
Highly efficient expression of proteins encoded by recombinant vaccinia virus in lymphocytes.
Scandinavian journal of immunology 1991;34(5):619-26.
1991: J M Freije; M Muñoz; Carlos López-Otín; E Viñuela
A general method to cleave a known DNA sequence at any site.
BioTechniques 1991;11(4):432-4, 436.
1991: M Boursnell; K Shaw; R J Yáñez; E Viñuela; L Dixon
The sequences of the ribonucleotide reductase genes from African swine fever virus show considerable homology with those of the orthopoxvirus, vaccinia virus.
Virology 1991;184(1):411-6.
1991: R J Yáñez; A Moya; E Viñuela; E Domingo
Repetitive nucleotide sequencing of a dispensable DNA segment in a clonal population of African swine fever virus.
Virus research 1991;20(3):265-72.
1991: E O Bockamp; R Blasco; E Viñuela
Escherichia coli thymidine kinase: nucleotide sequence of the gene and relationships to other thymidine kinases.
Gene 1991;101(1):9-14.
1991: Angel L Carrascosa; Isabel Sastre; E Viñuela
African swine fever virus attachment protein.
Journal of virology 1991;65(5):2283-9.
1991: A Alcamí; E Viñuela
Fc receptors do not mediate African swine fever virus replication in macrophages.
Virology 1991;181(2):756-9.
1991: A Camacho; E Viñuela
Protein p22 of African swine fever virus: an early structural protein that is incorporated into the membrane of infected cells.
Virology 1991;181(1):251-7.
1990: I de la Vega; E Viñuela; R Blasco
Genetic variation and multigene families in African swine fever virus.
Virology 1990;179(1):234-46.
1990: A Alcamí; Angel L Carrascosa; E Viñuela
Interaction of African swine fever virus with macrophages.
Virus research 1990;17(2):93-104.
1990: R Blasco; Carlos López-Otín; M Muñóz; E O Bockamp; Carmen Simón-Mateo; E Viñuela
Sequence and evolutionary relationships of African swine fever virus thymidine kinase.
Virology 1990;178(1):301-4.
1990: Jose-Carlos Gutierrez-Ramos; JOSE LUIS ANDREU SANCHEZ; Yolanda Revilla; E Viñuela; Carmen Martinez
Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus.
Nature 1990;346(6281):271-4.
1990: M Agüero; R Blasco; P Wilkinson; E Viñuela
Analysis of naturally occurring deletion variants of African swine fever virus: multigene family 110 is not essential for infectivity or virulence in pigs.
Virology 1990;176(1):195-204.
1990: A González; Victor Calvo; F Almazán; J M Almendral; Juan Ramirez; I de la Vega; R Blasco; E Viñuela
Multigene families in African swine fever virus: family 360.
Journal of virology 1990;64(5):2073-81.
1990: J M Almendral; F Almazán; R Blasco; E Viñuela
Multigene families in African swine fever virus: family 110.
Journal of virology 1990;64(5):2064-72.
1990: Carlos López-Otín; J M Freije; Francisco Parra; E Méndez; E Viñuela
Mapping and sequence of the gene coding for protein p72, the major capsid protein of African swine fever virus.
Virology 1990;175(2):477-84.
1989: R Blasco; I de la Vega; F Almazán; M Agüero; E Viñuela
Genetic variation of African swine fever virus: variable regions near the ends of the viral DNA.
Virology 1989;173(1):251-7.
1989: A Alcamí; Angel L Carrascosa; E Viñuela
The entry of African swine fever virus into Vero cells.
Virology 1989;171(1):68-75.
1989: Carlos López-Otín; Carmen Simón-Mateo; L Martínez; E Viñuela
Gly-Gly-X, a novel consensus sequence for the proteolytic processing of viral and cellular proteins.
The Journal of biological chemistry 1989;264(16):9107-10.
1989: A Alcamí; Angel L Carrascosa; E Viñuela
Saturable binding sites mediate the entry of African swine fever virus into Vero cells.
Virology 1989;168(2):393-8.
1989: R Blasco; M Agüero; J M Almendral; E Viñuela
Variable and constant regions in African swine fever virus DNA.
Virology 1989;168(2):330-8.
1988: I Esparza; J C González; E Viñuela
Effect of interferon-alpha, interferon-gamma and tumour necrosis factor on African swine fever virus replication in porcine monocytes and macrophages.
The Journal of general virology 1988;69 ( Pt 12)():2973-80.
1988: Yolanda Revilla; L Pena; E Viñuela
A protein of molar mass 12 kDa incorporates into the membrane of ASF virus-infected cells.
Virus research 1988;11(2):193-7.
1988: Carlos López-Otín; C Simón; E Méndez; E Viñuela
Mapping and sequence of the gene encoding protein p37, a major structural protein of African swine fever virus.
Virus genes 1988;1(3):291-303.
1988: J Salas; M L Salas; E Viñuela
Effect of inhibitors of the host cell RNA polymerase II on African swine fever virus multiplication.
Virology 1988;164(1):280-3.
1988: M L Salas; J Salas; E Viñuela
Phosphorylation of African swine fever virus proteins in vitro and in vivo.
Biochimie 1988;70(5):627-35.
1986: B García-Barreno; A Sanz; M L Nogal; E Viñuela; L Enjuanes
Monoclonal antibodies of African swine fever virus: antigenic differences among field virus isolates and viruses passaged in cell culture.
Journal of virology 1986;58(2):385-92.
1985: A Sanz; B García-Barreno; M L Nogal; E Viñuela; L Enjuanes
Monoclonal antibodies specific for African swine fever virus proteins.
Journal of virology 1985;54(1):199-206.