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David Boykin

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Claudia N Generaux; Mohamed A Ismail; Garrett R Ainslie; David W Boykin; Arlene S Bridges; Dhiren R Thakker; Richard R Tidwell; Mary F Paine
Compartmental and enzyme kinetic modeling to elucidate the biotransformation pathway of a centrally acting antitrypanosomal prodrug.
Raja Nhili; Paul Peixoto; Chad E Stephens; David W Boykin; W David Wilson; Sabine Depauw; Xavier Dezitter; Martine Duterque-Coquillaud; Abdelbasset Farahat; Sébastien Flajollet; Mohamed A Ismail; Arvind Kumar; Manoj M Munde; Marie-Hélène David-Cordonnier
Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines.
Carolyn S Reid; David W Boykin; Abdelbasset Farahat; Trupti Pandharkar; Xiaohua Zhu; Karl A Werbovetz
Antileishmanial bis-arylimidamides: DB766 analogs modified in the linker region and bis-arylimidamide structure-activity relationships.

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2013: Claudia N Generaux; Mohamed A Ismail; Garrett R Ainslie; David W Boykin; Arlene S Bridges; Dhiren R Thakker; Richard R Tidwell; Mary F Paine
Compartmental and enzyme kinetic modeling to elucidate the biotransformation pathway of a centrally acting antitrypanosomal prodrug.
Drug metabolism and disposition: the biological fate of chemicals 2013;41(2):518-28.
2013: Raja Nhili; Paul Peixoto; Chad E Stephens; David W Boykin; W David Wilson; Sabine Depauw; Xavier Dezitter; Martine Duterque-Coquillaud; Abdelbasset Farahat; Sébastien Flajollet; Mohamed A Ismail; Arvind Kumar; Manoj M Munde; Marie-Hélène David-Cordonnier
Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines.
Nucleic acids research 2013;41(1):125-38.
2012: Carolyn S Reid; David W Boykin; Abdelbasset Farahat; Trupti Pandharkar; Xiaohua Zhu; Karl A Werbovetz
Antileishmanial bis-arylimidamides: DB766 analogs modified in the linker region and bis-arylimidamide structure-activity relationships.
Bioorganic & medicinal chemistry letters 2012;22(22):6806-10.
2012: Benjamin W Newcomer; Julia F Ridpath; David W Boykin; Arvind Kumar; Mylissa S D Marley; John D Neill; M Daniel Givens
Efficacy of an antiviral compound to inhibit replication of multiple pestivirus species.
Antiviral research 2012;96(2):127-9.
2012: Moloy Banerjee; Reto Brun; Abdelbasset Farahat; Arvind Kumar; Manoj M Munde; Tanja Wenzler; Karl A Werbovetz; W David Wilson; Xiaohua Zhu; David W Boykin
Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides.
European journal of medicinal chemistry 2012;55():449-54.
2012: Xiaohua Zhu; W David Wilson; Sihyung Yang; Moloy Banerjee; David W Boykin; Denise da Gama Jaen Batista; Cristiane França da Silva; Maria de Nazaré Correia Soeiro; Abdelbasset Farahat; Carol E Green; Qiang Liu; Elen Mello de Souza; Jon C Mirsalis; Manoj Munde; Toufan Parman; Chad E Stephens; Michael Zhuo Wang; Karl A Werbovetz
Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies.
Antimicrobial agents and chemotherapy 2012;56(7):3690-9.
2012: Yang Liu; Richard R Tidwell; David W Boykin; Yun Chai; Arvind Kumar; W David Wilson
Designed compounds for recognition of 10 base pairs of DNA with two at binding sites.
Journal of the American Chemical Society 2012;134(11):5290-9.
2012: Rupesh Nanjunda; Manlio Palumbo; Claudia Sissi; Siming Wang; David W Boykin; Abdelbasset Farahat; Mohamed A Ismail; Arvind Kumar; Caterina Musetti; W David Wilson
Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents.
Current pharmaceutical design 2012;18(14):1934-47.
2012: Cristiane França da Silva; Patricia Bernardino da Silva; Anissa Daliry; Elen Mello de Souza; Abdelbasset Farahat; Erica Ripoll Hammer; Arvind Kumar; Zongying Liu; Gabriel M Oliveira; Ana Carolina Mondaine Rodrigues; Julianna Siciliano Araujo; Denise da Gama Jaen Batista; David W Boykin; Constança Britto; Maria de Nazaré Correia Soeiro
In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infection.
PloS one 2012;7(1):e30356.
2012: Benjamin W Newcomer; Kay P Riddell; Paul H Walz; Y Zhang; Dawn M Boothe; David W Boykin; Crisanta Cruz-Espindola; Christine C Dykstra; Patricia K Galik; Kellye S Joiner; Arvind Kumar; Mylissa S D Marley; M Daniel Givens
Antiviral treatment of calves persistently infected with bovine viral diarrhoea virus.
Antiviral chemistry & chemotherapy 2012;22(4):171-9.
2011: A Daliry; Solange L de Castro; Abdelbasset Farahat; Q Hu; Mohamed A Ismail; Arvind Kumar; Z Liu; M Munde; Raquel S Pacheco; Marize Q Pires; Cristiane F Silva; S Akay; David W Boykin; P Som; Chad E Stephens; W D Wilson; M N C Soeiro
The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA.
Antimicrobial agents and chemotherapy 2011;55(10):4765-73.
2011: Catharine J Collar; Karl A Werbovetz; David W Boykin; Xiaohua Zhu; W David Wilson
Molecular factors governing inhibition of arylimidamides against Leishmania: conservative computational modeling to improve chemotherapies.
Bioorganic & medicinal chemistry 2011;19(15):4552-61.
2011: Yang Liu; Stephen Neidle; Raja Nhili; Martial Say; Adalgisa Batista-Parra; David W Boykin; Sarah Chackal-Catoen; Marie-Hélène David-Cordonnier; Sabine Depauw; Abdelbasset Farahat; Mohamed A Ismail; Arvind Kumar; Michael P Lee; W David Wilson
Water-mediated binding of agents that target the DNA minor groove.
Journal of the American Chemical Society 2011;133(26):10171-83.
2011: Angela Nehrbass-Stuedli; Richard R Tidwell; David W Boykin; Reto Brun
Novel diamidines with activity against Babesia divergens in vitro and Babesia microti in vivo.
Antimicrobial agents and chemotherapy 2011;55(7):3439-45.
2011: Cristiane França Da Silva; Angela C V Junqueira; Marli Maria Lima; Alvaro J Romanha; Policarpo Ademar Sales Junior; Chad E Stephens; Phanneth Som; David W Boykin; Maria de Nazaré Correia Soeiro
In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi.
The Journal of antimicrobial chemotherapy 2011;66(6):1295-7.
2011: Rebecca A Hunt; Manoj Munde; Arvind Kumar; Mohamed A Ismail; Abdelbasset Farahat; Reem K Arafa; Martial Say; Adalgisa Batista-Parra; Denise Tevis; David W Boykin; W David Wilson
Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures.
Nucleic acids research 2011;39(10):4265-74.
2011: Abdelbasset Farahat; Ekaterina Paliakov; Arvind Kumar; Alaa-Eldin M Barghash; Fatma E Goda; Hassan M Eisa; Tanja Wenzler; Reto Brun; Yang Liu; W David Wilson; David W Boykin
Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties.
Bioorganic & medicinal chemistry 2011;19(7):2156-67.
2011: Elen Mello de Souza; P B da Silva; A S G Nefertiti; M A Ismail; R K Arafa; B Tao; C K Nixon-Smith; David W Boykin; M N C Soeiro
Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi.
Experimental parasitology 2011;127(2):429-35.
2011: Denise da Gama Jaén Batista; Marcos Meuser Batista; David W Boykin; Constança Britto; Gabriel Melo de Oliveira; Ana Carolina Mondaine Rodrigues; Chad E Stephens; Maria de Nazaré Correia Soeiro
Combined treatment of heterocyclic analogues and benznidazole upon Trypanosoma cruzi in vivo.
PloS one 2011;6(7):e22155.
2010: Manoj Munde; Arvind Kumar; Raja Nhili; Sabine Depauw; Marie-Hélène David-Cordonnier; Mohamed A Ismail; Chad E Stephens; Abdelbasset Farahat; Adalgisa Batista-Parra; David W Boykin; W David Wilson
DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site.
Journal of molecular biology 2010;402(5):847-64.
2010: Denise da Gama Jaén Batista; Marcos Meuser Batista; Gabriel Melo de Oliveira; Patrícia Borges do Amaral; Joseli Lannes-Vieira; Constança Carvalho Britto; Angela Junqueira; Marli Maria Lima; Alvaro José Romanha; Policarpo Ademar Sales Junior; Chad E Stephens; David W Boykin; Maria de Nazaré Correia Soeiro
Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment.
Antimicrobial agents and chemotherapy 2010;54(7):2940-52.
2010: Zhuo Wang; Xiaohua Zhu; Anuradha Srivastava; Qiang Liu; J Mark Sweat; Trupti Pandharkar; Chad E Stephens; Ed Riccio; Toufan Parman; Manoj Munde; Swati Mandal; Rentala Madhubala; Richard R Tidwell; W David Wilson; David W Boykin; James Edwin Hall; Dennis E Kyle; Karl A Werbovetz
Novel arylimidamides for treatment of visceral leishmaniasis.
Antimicrobial agents and chemotherapy 2010;54(6):2507-16.
2010: Danuta Branowska; Abdelbasset Farahat; Arvind Kumar; Tanja Wenzler; Reto Brun; Yang Liu; W David Wilson; David W Boykin
Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles.
Bioorganic & medicinal chemistry 2010;18(10):3551-8.
2010: Kirsten Gillingwater; Arvind Kumar; Mohamed A Ismail; Reem K Arafa; Chad E Stephens; David W Boykin; Richard R Tidwell; Reto Brun
In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi.
Veterinary parasitology 2010;169(3-4):264-72.
2010: D G J Batista; M G O Pacheco; A Kumar; D Branowska; M A Ismail; L Hu; David W Boykin; M N C Soeiro
Biological, ultrastructural effect and subcellular localization of aromatic diamidines in Trypanosoma cruzi.
Parasitology 2010;137(2):251-9.
2010: Abdelbasset Farahat; Arvind Kumar; Martial Say; Alaa El-Din M Barghash; Fatma E Goda; Hassan M Eisa; Tanja Wenzler; Reto Brun; Yang Liu; Leah Mickelson; W David Wilson; David W Boykin
Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines.
Bioorganic & medicinal chemistry 2010;18(2):557-66.
2009: Zong-Ying Liu; Yue-Ming Wang; Zhuo-Rong Li; Jian-Dong Jiang; David W Boykin
Synthesis and anticancer activity of novel 3,4-diarylthiazol-2(3H)-ones (imines).
Bioorganic & medicinal chemistry letters 2009;19(19):5661-4.
2009: Laixing Hu; Reem K Arafa; Mohamed A Ismail; Alpa Patel; Manoj Munde; David W. Wilson; Tanja Wenzler; Reto Brun; David W Boykin
Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum.
Bioorganic & medicinal chemistry 2009;17(18):6651-8.
2009: Denise S Tevis; Arvind Kumar; Chad E Stephens; David W Boykin; David W. Wilson
Large, sequence-dependent effects on DNA conformation by minor groove binding compounds.
Nucleic acids research 2009;37(16):5550-8.
2009: Michele Gabriele de Oliveira Pacheco; Cristiane França da Silva; Elen Mello de Souza; Marcos Meuser Batista; Patrícia Bernardino da Silva; Arvind Kumar; Chad E Stephens; David W Boykin; Maria de Nazaré Correia Soeiro
Trypanosoma cruzi: activity of heterocyclic cationic molecules in vitro.
Experimental parasitology 2009;123(1):73-80.
2009: Laixing Hu; Maureen L Kully; David W Boykin; Norman Abood
Synthesis and structure-activity relationship of dicationic diaryl ethers as novel potent anti-MRSA and anti-VRE agents.
Bioorganic & medicinal chemistry letters 2009;19(16):4626-9.
2009: Maria de Nazaré Correia Soeiro; Andreia P Dantas; Anissa Daliry; Cristiane F da Silva; Denise G J Batista; Elen Mello de Souza; Gabriel M Oliveira; Kelly Salomão; Marcos Meuser Batista; Michelle G O Pacheco; Patrícia Bernardino da Silva; Ricardo M Santa-Rita; Rubem F S Menna Barreto; David W Boykin; Solange Lisboa de Castro
Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies.
Memórias do Instituto Oswaldo Cruz 2009;104 Suppl 1():301-10.
2009: Laixing Hu; Maureen L Kully; David W Boykin; Norman Abood
Optimization of the central linker of dicationic bis-benzimidazole anti-MRSA and anti-VRE agents.
Bioorganic & medicinal chemistry letters 2009;19(13):3374-7.
2009: Laixing Hu; Maureen L Kully; David W Boykin; Norman Abood
Synthesis and in vitro activity of dicationic bis-benzimidazoles as a new class of anti-MRSA and anti-VRE agents.
Bioorganic & medicinal chemistry letters 2009;19(5):1292-5.
2009: Maryam Rahimian; Arvind Kumar; Martial Say; Stanislav A Bakunov; David W Boykin; Richard R Tidwell; David W. Wilson
Minor groove binding compounds that jump a gc base pair and bind to adjacent AT base pair sites.
Biochemistry 2009;48(7):1573-83.
2008: Reem K Arafa; Mohamed A Ismail; Manoj Munde; David W. Wilson; Tanja Wenzler; Reto Brun; David W Boykin
Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents.
European journal of medicinal chemistry 2008;43(12):2901-8.
2008: Laixing Hu; Zhuo-Rong Li; Jian-Dong Jiang; David W Boykin
Novel diaryl or heterocyclic sulfonamides as antimitotic agents.
Anti-cancer agents in medicinal chemistry 2008;8(7):739-45.
2008: Cristiane França da Silva; Marcos Meuser Batista; Denise da Gama Jaen Batista; Elen Mello de Souza; Patrícia Bernardino da Silva; Gabriel Melo de Oliveira; Andrea Souza Meuser; Abdur-Rafay Shareef; David W Boykin; Maria de Nazaré Correia Soeiro
In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi.
Antimicrobial agents and chemotherapy 2008;52(9):3307-14.
2008: David W. Wilson; Farial A Tanious; Amanda Mathis; Denise Tevis; James Edwin Hall; David W Boykin
Antiparasitic compounds that target DNA.
Biochimie 2008;90(7):999-1014.
2008: M N C Soeiro; Solange L de Castro; Elen Mello de Souza; D G J Batista; Cristiane F Silva; David W Boykin
Diamidine activity against trypanosomes: the state of the art.
Current molecular pharmacology 2008;1(2):151-61.
2008: Alexa C Rosypal; Karl A Werbovetz; Manar Salem; Chad E Stephens; Arvind Kumar; David W Boykin; James Edwin Hall; Richard R Tidwell
Inhibition by Dications of in vitro growth of Leishmania major and Leishmania tropica: causative agents of old world cutaneous leishmaniasis.
The Journal of parasitology 2008;94(3):743-9.
2008: Paul Peixoto; Yang Liu; Sabine Depauw; Marie-Paule Hildebrand; David W Boykin; Christian Bailly; David W. Wilson; Marie-Hélène David-Cordonnier
Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication.
Nucleic acids research 2008;36(10):3341-53.
2008: Mohamed A Ismail; Reem K Arafa; Tanja Wenzler; Reto Brun; Farial A Tanious; David W. Wilson; David W Boykin
Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.
Bioorganic & medicinal chemistry 2008;16(2):683-91.
2008: Laixing Hu; Reem K Arafa; Mohamed A Ismail; Tanja Wenzler; Reto Brun; Manoj Munde; David W. Wilson; Sandra Nzimiro; Serene Samyesudhas; Karl A Werbovetz; David W Boykin
Azaterphenyl diamidines as antileishmanial agents.
Bioorganic & medicinal chemistry letters 2008;18(1):247-51.
2008: Syed M Rahmathullah; Richard R Tidwell; Susan K Jones; James Edwin Hall; David W Boykin
Carbamate prodrugs of N-alkylfuramidines.
European journal of medicinal chemistry 2008;43(1):174-7.
2007: Laixing Hu; Zhuo-Rong Li; Jian-Nong Li; Jinrong Qu; Jian-Dong Jiang; David W Boykin
3-(2'-Bromopropionylamino)-benzamides as novel S-phase arrest agents.
Bioorganic & medicinal chemistry letters 2007;17(24):6847-52.
2007: Yang Liu; Arvind Kumar; David W Boykin; David W. Wilson
Sequence and length dependent thermodynamic differences in heterocyclic diamidine interactions at AT base pairs in the DNA minor groove.
Biophysical chemistry 2007;131(1-3):1-14.
2007: Manoj Munde; Mohamed A Ismail; Reem K Arafa; Paul Peixoto; Catharine J Collar; Yang Liu; Laixing Hu; Marie-Hélène David-Cordonnier; Amélie Lansiaux; Christian Bailly; David W Boykin; David W. Wilson
Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif.
Journal of the American Chemical Society 2007;129(44):13732-43.
2007: Cristiane F Silva; Marcos B Meuser; Elen Mello de Souza; M N L Meirelles; Chad E Stephens; P Som; David W Boykin; M N C Soeiro
Cellular effects of reversed amidines on Trypanosoma cruzi.
Antimicrobial agents and chemotherapy 2007;51(11):3803-9.
2007: Amanda M Mathis; Arlene Bridges; Mohamed A Ismail; Arvind Kumar; Iris Francesconi; Mariappan Anbazhagan; Qiyue Hu; Farial A Tanious; Tanja Wenzler; Janelle Y Saulter; David W. Wilson; Reto Brun; David W Boykin; Richard R Tidwell; James Edwin Hall
Diphenyl furans and aza analogs: effects of structural modification on in vitro activity, DNA binding, and accumulation and distribution in trypanosomes.
Antimicrobial agents and chemotherapy 2007;51(8):2801-10.
2007: Laixing Hu; Jian-Dong Jiang; Jinrong Qu; Yan Li; Jie Jin; Zhuo-Rong Li; David W Boykin
Novel potent antimitotic heterocyclic ketones: synthesis, antiproliferative activity, and structure-activity relationships.
Bioorganic & medicinal chemistry letters 2007;17(13):3613-7.
2007: Cristiane F Silva; Marcos Meuser Batista; Renata Alves Mota; Elen Mello de Souza; Chad E Stephens; Phanneth Som; David W Boykin; Maria de Nazaré Correia Soeiro
Activity of "reversed" diamidines against Trypanosoma cruzi "in vitro".
Biochemical pharmacology 2007;73(12):1939-46.
2007: Manoj Munde; Michael Lee; Stephen Neidle; Reem K Arafa; David W Boykin; Yang Liu; Christian Bailly; David W. Wilson
Induced fit conformational changes of a "reversed amidine" heterocycle: optimized interactions in a DNA minor groove complex.
Journal of the American Chemical Society 2007;129(17):5688-98.
2007: Alexa C Rosypal; James Edwin Hall; Svetlana Bakunova; Donald A Patrick; Stanislav Bakunov; Chad E Stephens; Arvind Kumar; David W Boykin; Richard R Tidwell
In vitro activity of dicationic compounds against a North American foxhound isolate of Leishmania infantum.
Veterinary parasitology 2007;145(3-4):207-16.
2007: Jose L Gonzalez; Chad E Stephens; Tanja Wenzler; Reto Brun; Farial A Tanious; David W. Wilson; Todd Barszcz; Karl A Werbovetz; David W Boykin
Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes.
European journal of medicinal chemistry 2007;42(4):552-7.
2007: Laixing Hu; Zhuo-Rong Li; Yue-ming Wang; Yanbin Wu; Jian-Dong Jiang; David W Boykin
Novel pyridinyl and pyrimidinylcarbazole sulfonamides as antiproliferative agents.
Bioorganic & medicinal chemistry letters 2007;17(5):1193-6.
2007: Elizabeth W White; Farial A Tanious; Mohamed A Ismail; Anthony P Reszka; Stephen Neidle; David W Boykin; David W. Wilson
Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge.
Biophysical chemistry 2007;126(1-3):140-53.
2006: Zhuo Wang; Janelle Y Saulter; Etsuko Usuki; Yen-Ling Cheung; Michael Hall; Arlene Bridges; Greg Loewen; Oliver T Parkinson; Chad E Stephens; James L Allen; Darryl C Zeldin; David W Boykin; Richard R Tidwell; Andrew Parkinson; Mary F Paine; James Edwin Hall
CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime].
Drug metabolism and disposition: the biological fate of chemicals 2006;34(12):1985-94.
2006: Sarah Chackal-Catoen; Yi Miao; David W. Wilson; Tanja Wenzler; Reto Brun; David W Boykin
Dicationic DNA-targeted antiprotozoal agents: naphthalene replacement of benzimidazole.
Bioorganic & medicinal chemistry 2006;14(22):7434-45.
2006: Laixing Hu; Zhuo-Rong Li; Yan Li; Jinrong Qu; Yi-He Ling; Jian-Dong Jiang; David W Boykin
Synthesis and structure-activity relationships of carbazole sulfonamides as a novel class of antimitotic agents against solid tumors.
Journal of medicinal chemistry 2006;49(21):6273-82.
2006: Elen Mello de Souza; Gabriel M Oliveira; David W Boykin; Arvind Kumar; Qiyue Hu; Maria de Nazaré C Soeiro
Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo.
The Journal of antimicrobial chemotherapy 2006;58(3):610-4.
2006: Mohamed A Ismail; Reem K Arafa; Reto Brun; Tanja Wenzler; Yi Miao; David W. Wilson; Claudia Generaux; Arlene Bridges; James Edwin Hall; David W Boykin
Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues.
Journal of medicinal chemistry 2006;49(17):5324-32.
2006: Elen Mello de Souza; Rubem F S Menna-Barreto; Tania C Araújo-Jorge; A Kumar; Qiyue Hu; David W Boykin; M N C Soeiro
Antiparasitic activity of aromatic diamidines is related to apoptosis-like death in Trypanosoma cruzi.
Parasitology 2006;133(Pt 1):75-9.
2006: Amanda M Mathis; Jacqueline L Holman; Lisa M Sturk; Mohamed A Ismail; David W Boykin; Richard R Tidwell; James Edwin Hall
Accumulation and intracellular distribution of antitrypanosomal diamidine compounds DB75 and DB820 in African trypanosomes.
Antimicrobial agents and chemotherapy 2006;50(6):2185-91.
2006: Prashanth Athri; Tanja Wenzler; Patricia Ruiz; Reto Brun; David W Boykin; Richard R Tidwell; David W. Wilson
3D QSAR on a library of heterocyclic diamidine derivatives with antiparasitic activity.
Bioorganic & medicinal chemistry 2006;14(9):3144-52.
2005: Mohamed A Ismail; Adalgisa Batista-Parra; Yi Miao; David W. Wilson; Tanja Wenzler; Reto Brun; David W Boykin
Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents.
Bioorganic & medicinal chemistry 2005;13(24):6718-26.
2005: Janelle Y Saulter; Joseph R Kurian; Lauren A Trepanier; Richard R Tidwell; Arlene Bridges; David W Boykin; Chad E Stephens; Mariappan Anbazhagan; James Edwin Hall
Unusual dehydroxylation of antimicrobial amidoxime prodrugs by cytochrome b5 and NADH cytochrome b5 reductase.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(12):1886-93.
2005: Yi Miao; Michael P H Lee; Gary N Parkinson; Adalgisa Batista-Parra; Mohamed A Ismail; Stephen Neidle; David W Boykin; David W. Wilson
Out-of-shape DNA minor groove binders: induced fit interactions of heterocyclic dications with the DNA minor groove.
Biochemistry 2005;44(45):14701-8.
2005: Hakan Göker; Seçkin Ozden; Sulhiye Yildiz; David W Boykin
Synthesis and potent antibacterial activity against MRSA of some novel 1,2-disubstituted-1H-benzimidazole-N-alkylated-5-carboxamidines.
European journal of medicinal chemistry 2005;40(10):1062-9.
2005: Reem K Arafa; Reto Brun; Tanja Wenzler; Farial A Tanious; David W. Wilson; Chad E Stephens; David W Boykin
Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs.
Journal of medicinal chemistry 2005;48(17):5480-8.
2005: M N C Soeiro; Elen Mello de Souza; Chad E Stephens; David W Boykin
Aromatic diamidines as antiparasitic agents.
Expert opinion on investigational drugs 2005;14(8):957-72.
2005: David W. Wilson; Binh Nguyen; Farial A Tanious; Amanda Mathis; James Edwin Hall; Chad E Stephens; David W Boykin
Dications that target the DNA minor groove: compound design and preparation, DNA interactions, cellular distribution and biological activity.
Current medicinal chemistry. Anti-cancer agents 2005;5(4):389-408.
2005: John H Ansede; Robert D Voyksner; Mohamed A Ismail; David W Boykin; Richard R Tidwell; James Edwin Hall
In vitro metabolism of an orally active O-methyl amidoxime prodrug for the treatment of CNS trypanosomiasis.
Xenobiotica; the fate of foreign compounds in biological systems 2005;35(3):211-26.
2005: Hakan Göker; David W Boykin; Sulhiye Yildiz
Synthesis and potent antimicrobial activity of some novel 2-phenyl or methyl-4H-1-benzopyran-4-ones carrying amidinobenzimidazoles.
Bioorganic & medicinal chemistry 2005;13(5):1707-14.
2005: Christian Bailly; Reem K Arafa; Farial A Tanious; William Laine; Christelle Tardy; Amélie Lansiaux; Pierre Colson; David W Boykin; David W. Wilson
Molecular determinants for DNA minor groove recognition: design of a bis-guanidinium derivative of ethidium that is highly selective for AT-rich DNA sequences.
Biochemistry 2005;44(6):1941-52.
2004: Jonathan B Chaires; Jinsong Ren; Donald Hamelberg; Arvind Kumar; Vandna Pandya; David W Boykin; David W. Wilson
Structural selectivity of aromatic diamidines.
Journal of medicinal chemistry 2004;47(23):5729-42.
2004: M Daniel Givens; David A Stringfellow; Christine C Dykstra; Kay P Riddell; Patricia K Galik; Eddie Sullivan; James M Robl; Poothappillai Kasinathan; Arvind Kumar; David W Boykin
Prevention and elimination of bovine viral diarrhea virus infections in fetal fibroblast cells.
Antiviral research 2004;64(2):113-8.
2004: Sirish Mallena; Michael P H Lee; Christian Bailly; Stephen Neidle; Arvind Kumar; David W Boykin; David W. Wilson
Thiophene-based diamidine forms a "super" at binding minor groove agent.
Journal of the American Chemical Society 2004;126(42):13659-69.
2004: Mohamed A Ismail; Reto Brun; Tanja Wenzler; Farial A Tanious; David W. Wilson; David W Boykin
Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents.
Bioorganic & medicinal chemistry 2004;12(20):5405-13.
2004: Andrea L Crowell; Chad E Stephens; Arvind Kumar; David W Boykin; W Evan Secor
Activities of dicationic compounds against Trichomonas vaginalis.
Antimicrobial agents and chemotherapy 2004;48(9):3602-5.
2004: Elen Mello de Souza; Amélie Lansiaux; C Bailly; David W. Wilson; Qiyue Hu; David W Boykin; Marcos Meuser Batista; Tania C Araújo-Jorge; M N C Soeiro
Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis.
Biochemical pharmacology 2004;68(4):593-600.
2004: John H Ansede; Mariappan Anbazhagan; Reto Brun; Judy D Easterbrook; James Edwin Hall; David W Boykin
O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection.
Journal of medicinal chemistry 2004;47(17):4335-8.
2004: Mohamed A Ismail; Reto Brun; Tanja Wenzler; Farial A Tanious; David W. Wilson; David W Boykin
Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents.
Journal of medicinal chemistry 2004;47(14):3658-64.
2004: Bin Tao; David W Boykin
Simple amine/Pd(OAc)(2)-catalyzed suzuki coupling reactions of aryl bromides under mild aerobic conditions.
The Journal of organic chemistry 2004;69(13):4330-5.
2004: Lian Zhou; Dhiren R Thakker; Robert D Voyksner; Mariappan Anbazhagan; David W Boykin; James Edwin Hall; Richard R Tidwell
Metabolites of an orally active antimicrobial prodrug, 2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime, identified by liquid chromatography/tandem mass spectrometry.
Journal of mass spectrometry : JMS 2004;39(4):351-60.
2004: Farial A Tanious; Donald Hamelberg; Christian Bailly; Agnieska Czarny; David W Boykin; David W. Wilson
DNA sequence dependent monomer-dimer binding modulation of asymmetric benzimidazole derivatives.
Journal of the American Chemical Society 2004;126(1):143-53.
2004: Zhijan Kang; Christine C Dykstra; David W Boykin
The synthesis of dicationic extended bis-benzimidazoles.
Molecules (Basel, Switzerland) 2004;9(3):158-63.
2003: Farial A Tanious; David W. Wilson; Lei Wang; Arvind Kumar; David W Boykin; Carine Marty; Brigitte Baldeyrou; Christian Bailly
Cooperative dimerization of a heterocyclic diamidine determines sequence-specific DNA recognition.
Biochemistry 2003;42(46):13576-86.
2003: Mohamed A Ismail; Reto Brun; Judy D Easterbrook; Farial A Tanious; David W. Wilson; David W Boykin
Synthesis and antiprotozoal activity of aza-analogues of furamidine.
Journal of medicinal chemistry 2003;46(22):4761-9.
2003: Edwin C Rowland; Deborah Moore-Lai; John Seed; Chad E Stephens; David W Boykin
Inhibition of in vitro intracellular growth of Trypanosoma cruzi by dicationic compounds.
The Journal of parasitology 2003;89(5):1078-80.
2003: M Daniel Givens; Christine C Dykstra; Kenny V Brock; David A Stringfellow; Arvind Kumar; Chad E Stephens; Hakan Goker; David W Boykin
Detection of inhibition of bovine viral diarrhea virus by aromatic cationic molecules.
Antimicrobial agents and chemotherapy 2003;47(7):2223-30.
2003: Chad E Stephens; Reto Brun; Manar M Salem; Karl A Werbovetz; Farial A Tanious; David W. Wilson; David W Boykin
The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani.
Bioorganic & medicinal chemistry letters 2003;13(12):2065-9.
2002: Amélie Lansiaux; Farial A Tanious; Zohar Mishal; Laurent Dassonneville; Arvind Kumar; Chad E Stephens; Qiyue Hu; David W. Wilson; David W Boykin; Christian Bailly
Distribution of furamidine analogues in tumor cells: targeting of the nucleus or mitochondria depending on the amidine substitution.
Cancer research 2002;62(24):7219-29.
2002: Liao Zhou; Kiho Lee; Dhiren R Thakker; David W Boykin; Richard R Tidwell; James Edwin Hall
Enhanced permeability of the antimicrobial agent 2,5-bis(4-amidinophenyl)furan across Caco-2 cell monolayers via its methylamidoidme prodrug.
Pharmaceutical research 2002;19(11):1689-95.
2002: Hakan Göker; Canan Kuş; David W Boykin; Sulhiye Yildiz; Nurten Altanlar
Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5-carbonitriles and their potent activity against Candida species.
Bioorganic & medicinal chemistry 2002;10(8):2589-96.
2002: Amélie Lansiaux; Laurent Dassonneville; Michaël Facompré; Arvind Kumar; Chad E Stephens; Miroslav Bajic; Farial A Tanious; David W. Wilson; David W Boykin; Christian Bailly
Distribution of furamidine analogues in tumor cells: influence of the number of positive charges.
Journal of medicinal chemistry 2002;45(10):1994-2002.
2002: Binh Nguyen; Christelle Tardy; Christian Bailly; Pierre Colson; Claude Houssier; Arvind Kumar; David W Boykin; David W. Wilson
Influence of compound structure on affinity, sequence selectivity, and mode of binding to DNA for unfused aromatic dications related to furamidine.
Biopolymers 2002;63(5):281-97.
2002: Lei Wang; Arvind Kumar; David W Boykin; Christian Bailly; David W. Wilson
Comparative thermodynamics for monomer and dimer sequence-dependent binding of a heterocyclic dication in the DNA minor groove.
Journal of molecular biology 2002;317(3):361-74.
2002: James J Brendle; Abram Outlaw; Arvind Kumar; David W Boykin; Donald A Patrick; Richard R Tidwell; Karl A Werbovetz
Antileishmanial activities of several classes of aromatic dications.
Antimicrobial agents and chemotherapy 2002;46(3):797-807.
2002: Lian Zhou; Robert D Voyksner; Dhiren R Thakker; Chad E Stephens; Mariappan Anbazhagan; David W Boykin; James Edwin Hall; Richard R Tidwell
Characterizing the fragmentation of 2,5-bis (4-amidinophenyl)furan-bis-O-methylamidoxime and selected metabolites using ion trap mass spectrometry.
Rapid communications in mass spectrometry : RCM 2002;16(11):1078-85.
2001: Christian Bailly; Christelle Tardy; L Wang; Bruce A Armitage; K Hopkins; Arvind Kumar; Gary B Schuster; David W Boykin; David W. Wilson
Recognition of ATGA sequences by the unfused aromatic dication DB293 forming stacked dimers in the DNA minor groove.
Biochemistry 2001;40(33):9770-9.
2001: P Bilik; Farial A Tanious; Arvind Kumar; David W. Wilson; David W Boykin; Pierre Colson; Claude Houssier; Michaël Facompré; Christelle Tardy; Christian Bailly
Novel dications with unfused aromatic systems: trithiophene and trifuran derivatives of furimidazoline.
Chembiochem : a European journal of chemical biology 2001;2(7-8):559-69.
2001: Chad E Stephens; Farial A Tanious; S Kim; David W. Wilson; Wiley A Schell; J R Perfect; Scott Franzblau; David W Boykin
Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents.
Journal of medicinal chemistry 2001;44(11):1741-8.
2001: G Xiao; Arvind Kumar; K Li; CT Rigl; Miroslav Bajic; T M Davis; David W Boykin; David W. Wilson
Inhibition of the HIV-1 rev-RRE complex formation by unfused aromatic cations.
Bioorganic & medicinal chemistry 2001;9(5):1097-113.
2001: Lei Wang; C Carrasco; Arvind Kumar; Chad E Stephens; Christian Bailly; David W Boykin; David W. Wilson
Evaluation of the influence of compound structure on stacked-dimer formation in the DNA minor groove.
Biochemistry 2001;40(8):2511-21.
2001: K Li; T M Davis; Christian Bailly; Arvind Kumar; David W Boykin; David W. Wilson
A heterocyclic inhibitor of the REV-RRE complex binds to RRE as a dimer.
Biochemistry 2001;40(5):1150-8.
2000: IJ Simpson; M Lee; Arvind Kumar; David W Boykin; Stephen Neidle
DNA minor groove interactions and the biological activity of 2,5-bis.
Bioorganic & medicinal chemistry letters 2000;10(23):2593-7.
2000: S Mazur; Farial A Tanious; D Ding; Arvind Kumar; David W Boykin; IJ Simpson; Stephen Neidle; David W. Wilson
A thermodynamic and structural analysis of DNA minor-groove complex formation.
Journal of molecular biology 2000;300(2):321-37.
2000: Lei Wang; Christian Bailly; Arvind Kumar; D Ding; Miroslav Bajic; David W Boykin; David W. Wilson
Specific molecular recognition of mixed nucleic acid sequences: an aromatic dication that binds in the DNA minor groove as a dimer.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):12-6.
1999: S M Rahmathullah; James Edwin Hall; BC Bender; DR McCurdy; Richard R Tidwell; David W Boykin
Prodrugs for amidines: synthesis and anti-Pneumocystis carinii activity of carbamates of 2,5-bis(4-amidinophenyl)furan.
Journal of medicinal chemistry 1999;42(19):3994-4000.
1999: Maurizio Del Poeta; A S Bixel; F Barchiesi; Richard R Tidwell; David W Boykin; G Scalise; John R Perfect
In-vitro activity of dicationic aromatic compounds and fluconazole against Cryptococcus neoformans and Candida spp.
The Journal of antimicrobial chemotherapy 1999;44(2):223-8.
1999: I Francesconi; David W. Wilson; Farial A Tanious; James Edwin Hall; BC Bender; Richard R Tidwell; DR McCurdy; David W Boykin
2,4-Diphenyl furan diamidines as novel anti-Pneumocystis carinii pneumonia agents.
Journal of medicinal chemistry 1999;42(12):2260-5.
1999: Christian Bailly; Laurent Dassonneville; C Carrasco; D Lucas; A Kumar; David W Boykin; David W. Wilson
Relationships between topoisomerase II inhibition, sequence-specificity and DNA binding mode of dicationic diphenylfuran derivatives.
Anti-cancer drug design 1999;14(1):47-60.
1998: Byron L Blagburn; K L Drain; Tracey M Land; R G Kinard; P H Moore; David S Lindsay; Donald A Patrick; David W Boykin; Richard R Tidwell
Comparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide, and paromomycin against Cryptosporidium parvum infections in a neonatal mouse model.
Antimicrobial agents and chemotherapy 1998;42(11):2877-82.
1998: Maurizio Del Poeta; Wiley A Schell; Christine C Dykstra; Susan Kilgore Jones; Richard R Tidwell; Arvind Kumar; David W Boykin; John R Perfect
In vitro antifungal activities of a series of dication-substituted carbazoles, furans, and benzimidazoles.
Antimicrobial agents and chemotherapy 1998;42(10):2503-10.
1998: Maurizio Del Poeta; Wiley A Schell; Christine C Dykstra; S Jones; Richard R Tidwell; A Czarny; Miroslav Bajic; Arvind Kumar; David W Boykin; John R Perfect
Structure-in vitro activity relationships of pentamidine analogues and dication-substituted bis-benzimidazoles as new antifungal agents.
Antimicrobial agents and chemotherapy 1998;42(10):2495-502.
1998: K T Hopkins; David W. Wilson; BC Bender; DR McCurdy; James Edwin Hall; Richard R Tidwell; Arvind Kumar; Miroslav Bajic; David W Boykin
Extended aromatic furan amidino derivatives as anti-Pneumocystis carinii agents.
Journal of medicinal chemistry 1998;41(20):3872-8.
1998: Byron L Blagburn; K L Drain; Tracey M Land; P H Moore; R G Kinard; David S Lindsay; Arvind Kumar; J Shi; David W Boykin; Richard R Tidwell
Dicationic furans inhibit development of Cryptosporidium parvum in HSD/ICR suckling Swiss mice.
The Journal of parasitology 1998;84(4):851-6.
1998: E Hildebrandt; David W Boykin; Arvind Kumar; Richard R Tidwell; Christine C Dykstra
Identification and characterization of an endo/exonuclease in Pneumocystis carinii that is inhibited by dicationic diarylfurans with efficacy against Pneumocystis pneumonia.
The Journal of eukaryotic microbiology 1998;45(1):112-21.
1998: David W Boykin; Arvind Kumar; G Xiao; David W. Wilson; BC Bender; DR McCurdy; James Edwin Hall; Richard R Tidwell
2,5-bis[4-(N-alkylamidino)phenyl]furans as anti-Pneumocystis carinii agents.
Journal of medicinal chemistry 1998;41(1):124-9.
1997: K Li; M Fernandez-Saiz; CT Rigl; Arvind Kumar; K G Ragunathan; A W McConnaughie; David W Boykin; H J Schneider; David W. Wilson
Design and analysis of molecular motifs for specific recognition of RNA.
Bioorganic & medicinal chemistry 1997;5(6):1157-72.
1997: Maria L Zapp; D W Young; A Kumar; Ravinder Singh; David W Boykin; David W. Wilson; M R Green
Modulation of the Rev-RRE interaction by aromatic heterocyclic compounds.
Bioorganic & medicinal chemistry 1997;5(6):1149-55.
1996: J O Trent; George R Clark; A Kumar; David W. Wilson; David W Boykin; James Edwin Hall; Richard R Tidwell; B L Blagburn; Stephen Neidle
Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2.
Journal of medicinal chemistry 1996;39(23):4554-62.
1996: L Ratmeyer; Maria L Zapp; M R Green; R Vinayak; Arvind Kumar; David W Boykin; David W. Wilson
Inhibition of HIV-1 Rev-RRE interaction by diphenylfuran derivatives.
Biochemistry 1996;35(42):13689-96.
1996: C A Laughton; Farial A Tanious; C M Nunn; David W Boykin; David W. Wilson; Stephen Neidle
A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity.
Biochemistry 1996;35(18):5655-61.
1996: David W. Wilson; L Ratmeyer; M Zhao; D Ding; A W McConnaughie; Arvind Kumar; David W Boykin
Design and analysis of RNA structure-specific agents as potential antivirals.
Journal of molecular recognition : JMR 1996;9(2):187-96.
1996: Arvind Kumar; W Wilson; B Bender; David W Boykin; Christine C Dykstra; J Hall; S Jones; Richard R Tidwell
Anti-Pneumocystis carinii pneumonia activity of dicationic 2,4-diarylpyrimidines.
European journal of medicinal chemistry 1996;31(10):767-73.
1996: G Karminski-Zamola; V Tralić-Kulenović; L Fiser-Jakić; Miroslav Bajic; David W Boykin
Electron impact mass spectra of some bis-(2-benzothiazolyl)furans and bis-(2-benzothiazolyl)thiophenes.
Rapid communications in mass spectrometry : RCM 1996;10(13):1621-5.
1995: AA Wood; C M Nunn; A Czarny; David W Boykin; Stephen Neidle
Variability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2.
Nucleic acids research 1995;23(18):3678-84.
1995: M Zhao; L Ratmeyer; R G Peloquin; S Yao; Arvind Kumar; J Spychala; David W Boykin; David W. Wilson
Small changes in cationic substituents of diphenylfuran derivatives have major effects on the binding affinity and the binding mode with RNA helical duplexes.
Bioorganic & medicinal chemistry 1995;3(6):785-94.
1995: David W Boykin; Arvind Kumar; J Spychala; M Zhou; R J Lombardy; David W. Wilson; Christine C Dykstra; S K Jones; James Edwin Hall; Richard R Tidwell
Dicationic diarylfurans as anti-Pneumocystis carinii agents.
Journal of medicinal chemistry 1995;38(6):912-6.
1995: G Karminski-Zamola; V Tralić-Kulenović; L Fiser-Jakić; M Bajié; David W Boykin
Electron impact mass spectra of some 1-(2-furyl)- and 1-(2-thienyl)-2-(2-benzothiazolyl)ethenes.
Rapid communications in mass spectrometry : RCM 1995;9(14):1345-8.
1995: G Karminski-Zamola; M Malesević; N Blazević; M Bajić; David W Boykin
Mass spectral fragmentation patterns of some new 3,7-dichloro-benzo[1,2-b:4,5-b']dithiophene-2,6-dicarboxylic acid dianilides and 3,5-dichloro-dithieno[3,2-b:2',3'-d]thiophene-2,6-dicarboxylic acid dianilides. II.
Rapid communications in mass spectrometry : RCM 1995;9(5):400-4.
1995: G Karminski-Zamola; J Dogan; David W Boykin; M Bajić
Mass spectral fragmentation patterns of some new benzo[b]thiophene- and thieno[2,3-b]thiophene-2,5-dicarbonyldichlorides and -dicarbonyldianilides and anilidoquinolones.
Rapid communications in mass spectrometry : RCM 1995;9(4):282-8.
1995: G Karminski-Zamola; L Fiser-Jakić; M Bajić; David W Boykin
Mass spectra of dicarboxylic acid dianilides III. Furan-based compounds.
Rapid communications in mass spectrometry : RCM 1995;9(9):781-2.
1995: G Karminski-Zamola; L Fiser-Jakić; M Bajić; David W Boykin
Mass spectral fragmentation patterns of some 2-methyl-3-furancarboxanilides and 2-methyl-3-furancarbothioanilides. II.
Rapid communications in mass spectrometry : RCM 1995;9(9):778-80.
1994: A W McConnaughie; J Spychala; M Zhao; David W Boykin; David W. Wilson
Design and synthesis of RNA-specific groove-binding cations: implications for antiviral drug design.
Journal of medicinal chemistry 1994;37(8):1063-9.
1994: Farial A Tanious; J Spychala; Arvind Kumar; K Greene; David W Boykin; David W. Wilson
Different binding mode in AT and GC sequences for unfused-aromatic dications.
Journal of biomolecular structure & dynamics 1994;11(5):1063-83.
1993: David W. Wilson; L Ratmeyer; M Zhao; Lucjan Strekowski; David W Boykin
The search for structure-specific nucleic acid-interactive drugs: effects of compound structure on RNA versus DNA interaction strength.
Biochemistry 1993;32(15):4098-104.
1991: H P Hopkins; Y Ming; David W. Wilson; David W Boykin
Intercalation binding of 6-substituted naphthothiopheneamides to DNA: enthalpy and entropy components.
Biopolymers 1991;31(9):1105-14.
1990: David W. Wilson; Farial A Tanious; Henryk J. Barton; R L Wydra; R L Jones; David W Boykin; Lucjan Strekowski
The interaction of unfused polyaromatic heterocycles with DNA: intercalation, groove-binding and bleomycin amplification.
Anti-cancer drug design 1990;5(1):31-42.
1987: David W. Wilson; S Chandrasekaran; S Kusuma; David W Boykin; Stephen Neidle
The influence of intercalator structure on DNA binding strength: the importance of side chain orientation.
Journal of biomolecular structure & dynamics 1987;5(2):327-44.
1986: David W. Wilson; Y H Wang; S Kusuma; S Chandrasekaran; David W Boykin
The effect of intercalator structure on binding strength and base-pair specificity in DNA interactions.
Biophysical chemistry 1986;24(2):101-9.