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Joseph Vita

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Matthew A Kluge; Jessica L Fetterman; Joseph A Vita
Mitochondria and endothelial function.
Soroosh Kiani; Rebecca M Leleiko; Farhana Sharmeen; Corey E Tabit; Joseph A Vita; Jonathan G Aasen; Robert T Eberhardt; Alik Farber; Noyan Gokce; Monika Holbrook; Abhishek Khemka; Naomi M Hamburg
Peripheral artery disease is associated with severe impairment of vascular function.
Corey E Tabit; Joseph A Vita; Mustali M Dohadwala; Melissa G Farb; Jessica L Fetterman; Alissa A Frame; Noyan Gokce; Aaron Held; Monika Holbrook; Soroosh Kiani; Matthew A Kluge; James Rosenzweig; Neil Ruderman; Sherene M Shenouda; Naomi M Hamburg
Protein kinase C-β contributes to impaired endothelial insulin signaling in humans with diabetes mellitus.

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2013: Matthew A Kluge; Jessica L Fetterman; Joseph A Vita
Mitochondria and endothelial function.
Circulation research 2013;112(8):1171-88.
2013: Soroosh Kiani; Rebecca M Leleiko; Farhana Sharmeen; Corey E Tabit; Joseph A Vita; Jonathan G Aasen; Robert T Eberhardt; Alik Farber; Noyan Gokce; Monika Holbrook; Abhishek Khemka; Naomi M Hamburg
Peripheral artery disease is associated with severe impairment of vascular function.
Vascular medicine (London, England) 2013;18(2):72-8.
2013: Corey E Tabit; Joseph A Vita; Mustali M Dohadwala; Melissa G Farb; Jessica L Fetterman; Alissa A Frame; Noyan Gokce; Aaron Held; Monika Holbrook; Soroosh Kiani; Matthew A Kluge; James Rosenzweig; Neil Ruderman; Sherene M Shenouda; Naomi M Hamburg
Protein kinase C-β contributes to impaired endothelial insulin signaling in humans with diabetes mellitus.
Circulation 2013;127(1):86-95.
2012: Tinoy J Kizhakekuttu; Joseph A Vita; Jingli Wang; Kodlipet Dharmashankar; David D Gutterman; Rong Ying; Michael E Widlansky
Adverse alterations in mitochondrial function contribute to type 2 diabetes mellitus-related endothelial dysfunction in humans.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(10):2531-9.
2012: George Thanassoulis; Joseph A Vita; Michael E Widlansky; Emelia J Benjamin; Naomi M Hamburg; Martin G Larson; Daniel Levy; Asya Lyass; Gary F Mitchell; Christopher J O'Donnell; Ramachandran S Vasan
Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham Heart Study.
Circulation 2012;125(23):2836-43.
2012: Corey E Tabit; Joseph A Vita; Michael E Widlansky; Mustali M Dohadwala; Mai-Ann Duess; Alissa A Frame; Monica Holbrook; John F Keaney; Brian H Kim; Matthew A Kluge; Aaron Levit; Sherene M Shenouda; Naomi M Hamburg
Effect of sulfasalazine on inflammation and endothelial function in patients with established coronary artery disease.
Vascular medicine (London, England) 2012;17(2):101-7.
2012: Melissa G Farb; Antonino J Fiscale; Lisa Ganley-Leal; Caroline M Apovian; Sherman J Bigornia; Brian Carmine; Bahadir Ercan; Donald T Hess; Yanmei Liang; Melanie Mott; Joseph A Vita; Michael E Widlansky; Noyan Gokce
Arteriolar function in visceral adipose tissue is impaired in human obesity.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(2):467-73.
2011: Apranta Deka; Joseph A Vita
Tea and cardiovascular disease.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(2):136-45.
2011: Sherene M Shenouda; Orian S Shirihai; Corey E Tabit; Michael E Widlansky; Guoquan Xu; Tara L Caiano; Kai Chen; Mai-Ann Duess; Alissa A Frame; Naomi M Hamburg; Mor-Li Hartman; Monika Holbrook; Lija Joseph; Brian Kim; Matthew A Kluge; Aaron Levit; Joseph A Vita
Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus.
Circulation 2011;124(4):444-53.
2011: Melissa G Farb; Jane E Freedman; Caroline M Apovian; Sherman Bigornia; Donald T Hess; Lija Joseph; Kristine M Morin; Melanie Mott; Kahraman Tanriverdi; Joseph A Vita; Noyan Gokce
Reduced adipose tissue inflammation represents an intermediate cardiometabolic phenotype in obesity.
Journal of the American College of Cardiology 2011;58(3):232-7.
2011: Mustali M Dohadwala; Monika Holbrook; Naomi M Hamburg; Sherene M Shenouda; William B Chung; Megan Titas; Matthew A Kluge; Na Wang; Joseph Palmisano; Paul E Milbury; Jeffrey B Blumberg; Joseph A Vita
Effects of cranberry juice consumption on vascular function in patients with coronary artery disease.
The American journal of clinical nutrition 2011;93(5):934-40.
2011: Naomi M Hamburg; Joseph Palmisano; Martin G Larson; Lisa M Sullivan; Birgitta T Lehman; Ramachandran S Vasan; Daniel Levy; Gary F Mitchell; Joseph A Vita; Emelia J Benjamin
Relation of brachial and digital measures of vascular function in the community: the Framingham heart study.
Hypertension 2011;57(3):390-6.
2011: Xiaochao Wei; Jochen G Schneider; Sherene M Shenouda; Ada Lee; Dwight A Towler; Manu V Chakravarthy; Joseph A Vita; Clay F Semenkovich
De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.
The Journal of biological chemistry 2011;286(4):2933-45.
2010: Mustali M Dohadwala; Naomi M Hamburg; Monika Holbrook; Brian H Kim; Mai-Ann Duess; Aaron Levit; Megan Titas; William B Chung; Felix B Vincent; Tara L Caiano; Alissa A Frame; John F Keaney; Joseph A Vita
Effects of Concord grape juice on ambulatory blood pressure in prehypertension and stage 1 hypertension.
The American journal of clinical nutrition 2010;92(5):1052-9.
2010: Michael E Widlansky; Jingli Wang; Sherene M Shenouda; Tory M Hagen; Anthony R Smith; Tinoy J Kizhakekuttu; Matthew A Kluge; Dorothee Weihrauch; David D Gutterman; Joseph A Vita
Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes.
Translational research : the journal of laboratory and clinical medicine 2010;156(1):15-25.
2010: Naomi M Hamburg; Melanie M Mott; Sherman J Bigornia; Mai-Ann Duess; Matthew A Kluge; Donald T Hess; Caroline M Apovian; Joseph A Vita; Noyan Gokce
Maladaptive enlargement of the brachial artery in severe obesity is reversed with weight loss.
Vascular medicine (London, England) 2010;15(3):215-22.
2010: Sherman J Bigornia; Melanie M Mott; Donald T Hess; Caroline M Apovian; Marie E McDonnell; Mai-Ann Duess; Matthew A Kluge; Antonino J Fiscale; Joseph A Vita; Noyan Gokce
Long-term successful weight loss improves vascular endothelial function in severely obese individuals.
Obesity (Silver Spring, Md.) 2010;18(4):754-9.
2010: Corey E Tabit; William B Chung; Naomi M Hamburg; Joseph A Vita
Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications.
Reviews in endocrine & metabolic disorders 2010;11(1):61-74.
2009: Hassan A Chami; Michelle J Keyes; Joseph A Vita; Gary F Mitchell; Martin G Larson; Shuxia Fan; Ramachandran S Vasan; George T O'Connor; Emelia Benjamin; Daniel J Gottlieb
Brachial artery diameter, blood flow and flow-mediated dilation in sleep-disordered breathing.
Vascular medicine (London, England) 2009;14(4):351-60.
2009: Mustali M Dohadwala; Joseph A Vita
Grapes and cardiovascular disease.
The Journal of nutrition 2009;139(9):1788S-93S.
2009: Eiman Jahangir; Joseph A Vita; Diane E Handy; Monica Holbrook; Joseph Palmisano; Ryan Beal; Joseph Loscalzo; Robert T Eberhardt
The effect of L-arginine and creatine on vascular function and homocysteine metabolism.
Vascular medicine (London, England) 2009;14(3):239-48.
2009: William B Chung; Naomi M Hamburg; Monika Holbrook; Sherene M Shenouda; Mustali M Dohadwala; Dellara F Terry; Noyan Gokce; Joseph A Vita
The brachial artery remodels to maintain local shear stress despite the presence of cardiovascular risk factors.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(4):606-12.
2009: Hao G Nguyen; Amit Korach; Chey Collura; Benjamin R Eskenazi; Joseph A Vita; Oz M Shapira
Differential effects of natriuretic peptides on arterial and venous coronary artery bypass conduits.
The Annals of thoracic surgery 2009;87(3):748-56.
2008: John F Keaney; Izabella Lipinska; Martin G Larson; Josée Dupuis; Jane E Freedman; Naomi M Hamburg; Joseph M Massaro; Jian Rong; Patrice Sutherland; Joseph A Vita; Ramachandran S Vasan; Emelia Benjamin
Clinical correlates, heritability, and genetic linkage of circulating CD40 ligand in the Framingham Offspring Study.
American heart journal 2008;156(5):1003-1009.e1.
2008: Joseph A Vita; Monika Holbrook; Joseph Palmisano; Sherene M Shenouda; William B Chung; Naomi M Hamburg; Benjamin R Eskenazi; Lija Joseph; Oz M Shapira
Flow-induced arterial remodeling relates to endothelial function in the human forearm.
Circulation 2008;117(24):3126-33.
2008: Naomi M Hamburg; Michelle J Keyes; Martin G Larson; Ramachandran S Vasan; Renate Schnabel; Moira M Pryde; Gary F Mitchell; Jacob Sheffy; Joseph A Vita; Emelia Benjamin
Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study.
Circulation 2008;117(19):2467-74.
2008: Naomi M Hamburg; Martin G Larson; Joseph A Vita; Ramachandran S Vasan; Michelle J Keyes; Michael E Widlansky; Caroline S Fox; Gary F Mitchell; Daniel Levy; James B Meigs; Emelia Benjamin
Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease.
The American journal of cardiology 2008;101(1):82-8.
2007: Naomi M Hamburg; Craig J McMackin; Alex L Huang; Sherene M Shenouda; Michael E Widlansky; Eberhard Schulz; Noyan Gokce; Neil B Ruderman; John F Keaney; Joseph A Vita
Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2650-6.
2007: Alex L Huang; Annemarie E Silver; Elena Shvenke; David W Schopfer; Eiman Jahangir; Megan A Titas; Alex Shpilman; James O Menzoian; Michael T Watkins; Joseph D Raffetto; Gary H Gibbons; Jonathan Woodson; Palma M Shaw; Mandeep Dhadly; Robert T Eberhardt; John F Keaney; Noyan Gokce; Joseph A Vita
Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(10):2113-9.
2007: Sherene M Shenouda; Joseph A Vita
Effects of flavonoid-containing beverages and EGCG on endothelial function.
Journal of the American College of Nutrition 2007;26(4):366S-372S.
2007: Michael E Widlansky; Joseph A Vita; Michelle J Keyes; Martin G Larson; Naomi M Hamburg; Daniel Levy; Gary F Mitchell; Ewa Osypiuk; Ramachandran S Vasan; Emelia Benjamin
Relation of season and temperature to endothelium-dependent flow-mediated vasodilation in subjects without clinical evidence of cardiovascular disease (from the Framingham Heart Study).
The American journal of cardiology 2007;100(3):518-23.
2007: Michael E Widlansky; Naomi M Hamburg; Elad Anter; Monika Holbrook; David F Kahn; James G Elliott; John F Keaney; Joseph A Vita
Acute EGCG supplementation reverses endothelial dysfunction in patients with coronary artery disease.
Journal of the American College of Nutrition 2007;26(2):95-102.
2007: Craig J McMackin; Michael E Widlansky; Naomi M Hamburg; Alex L Huang; Susan Weller; Monika Holbrook; Noyan Gokce; Tory M Hagen; John F Keaney; Joseph A Vita
Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease.
Journal of clinical hypertension (Greenwich, Conn.) 2007;9(4):249-55.
2006: Flora Sam; Isaac Halickman; Joseph A Vita; Yamini Levitzky; L Adrienne Cupples; Joseph Loscalzo; Donald Allensworth-Davies
Predictors of improved left ventricular systolic function in an urban cardiomyopathy program.
The American journal of cardiology 2006;98(12):1622-6.
2006: Anthony Solages; Joseph A Vita; David J Thornton; Jessica Murray; Timothy Heeren; Donald E Craven; C Robert Horsburgh
Endothelial function in HIV-infected persons.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;42(9):1325-32.
2006: Eugene Kotlyar; Joseph A Vita; Michael R Winter; Eric H Awtry; Deborah A Siwik; John F Keaney; Douglas B Sawyer; L Adrienne Cupples; Wilson S Colucci; Flora Sam
The relationship between aldosterone, oxidative stress, and inflammation in chronic, stable human heart failure.
Journal of cardiac failure 2006;12(2):122-7.
2006: Oz M Shapira; Benjamin R Eskenazi; Elad Anter; Lija Joseph; Thomas G Christensen; Curtis T Hunter; Harold L Lazar; Joseph A Vita; Richard J Shemin; John F Keaney
Endoscopic versus conventional radial artery harvest for coronary artery bypass grafting: functional and histologic assessment of the conduit.
The Journal of thoracic and cardiovascular surgery 2006;131(2):388-94.
2006: Alex L Huang; Joseph A Vita
Effects of systemic inflammation on endothelium-dependent vasodilation.
Trends in cardiovascular medicine 2006;16(1):15-20.
2005: Stephen J Duffy; Elizabeth S Biegelsen; Robert T Eberhardt; David F Kahn; Bronwyn A Kingwell; Joseph A Vita
Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation.
Hypertension 2005;46(4):707-13.
2005: Josée Dupuis; Martin G Larson; Ramachandran S Vasan; Joseph M Massaro; Peter W F Wilson; Izabella Lipinska; Diane Corey; Joseph A Vita; John F Keaney; Emelia Benjamin
Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: evidence for susceptibility loci on 1q.
Atherosclerosis 2005;182(2):307-14.
2005: Michael E Widlansky; Stephen J Duffy; Naomi M Hamburg; Noyan Gokce; Beverly Warden; Sheila Wiseman; John F Keaney; Balz Frei; Joseph A Vita
Effects of black tea consumption on plasma catechins and markers of oxidative stress and inflammation in patients with coronary artery disease.
Free radical biology & medicine 2005;38(4):499-506.
2005: Noyan Gokce; Joseph A Vita; Marie McDonnell; Armour R Forse; Nawfal W Istfan; Maria Stoeckl; Izabella Lipinska; John F Keaney; Caroline M Apovian
Effect of medical and surgical weight loss on endothelial vasomotor function in obese patients.
The American journal of cardiology 2005;95(2):266-8.
2005: Craig J McMackin; Joseph A Vita
Update on nitric oxide-dependent vasodilation in human subjects.
Methods in enzymology 2005;396():541-53.
2005: Joseph A Vita
Polyphenols and cardiovascular disease: effects on endothelial and platelet function.
The American journal of clinical nutrition 2005;81(1 Suppl):292S-297S.
2004: Joseph A Vita; John F Keaney; Martin G Larson; Michelle J Keyes; Joseph M Massaro; Izabella Lipinska; Birgitta T Lehman; Shuxia Fan; Ewa Osypiuk; Peter W F Wilson; Ramachandran S Vasan; Gary F Mitchell; Emelia Benjamin
Brachial artery vasodilator function and systemic inflammation in the Framingham Offspring Study.
Circulation 2004;110(23):3604-9.
2004: Elad Anter; Shane R Thomas; Eberhard Schulz; Oz M Shapira; Joseph A Vita; John F Keaney
Activation of endothelial nitric-oxide synthase by the p38 MAPK in response to black tea polyphenols.
The Journal of biological chemistry 2004;279(45):46637-43.
2004: Joseph A Vita; Marie-Luise Brennan; Noyan Gokce; Shirley A Mann; Marlene Goormastic; Mehdi H Shishehbor; Marc S Penn; John F Keaney; Stanley L Hazen
Serum myeloperoxidase levels independently predict endothelial dysfunction in humans.
Circulation 2004;110(9):1134-9.
2004: John F Keaney; Joseph M Massaro; Martin G Larson; Ramachandran S Vasan; Peter W F Wilson; Izabella Lipinska; Diane Corey; Patrice Sutherland; Joseph A Vita; Emelia Benjamin
Heritability and correlates of intercellular adhesion molecule-1 in the Framingham Offspring Study.
Journal of the American College of Cardiology 2004;44(1):168-73.
2004: Emelia Benjamin; Martin G Larson; Michelle J Keyes; Gary F Mitchell; Ramachandran S Vasan; John F Keaney; Birgitta T Lehman; Shuxia Fan; Ewa Osypiuk; Joseph A Vita
Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study.
Circulation 2004;109(5):613-9.
2004: Andrew P Levy; Martin G Larson; Diane Corey; Rachel Lotan; Joseph A Vita; Emelia Benjamin
Haptoglobin phenotype and prevalent coronary heart disease in the Framingham offspring cohort.
Atherosclerosis 2004;172(2):361-5.
2004: Michael E Widlansky; Elizabeth S Biegelsen; Naomi M Hamburg; Stephen J Duffy; John F Keaney; Joseph A Vita
Coronary endothelial dysfunction is not rapidly reversible with ascorbic acid.
Free radical biology & medicine 2004;36(1):123-30.
2003: Joseph A Vita
Nitric oxide and vascular reactivity in African American patients with hypertension.
Journal of cardiac failure 2003;9(5 Suppl Nitric Oxide):S199-204; discussion S205-9.
2003: Michael E Widlansky; Noyan Gokce; John F Keaney; Joseph A Vita
The clinical implications of endothelial dysfunction.
Journal of the American College of Cardiology 2003;42(7):1149-60.
2003: Joseph A Vita
Tea consumption and cardiovascular disease: effects on endothelial function.
The Journal of nutrition 2003;133(10):3293S-3297S.
2003: Robert T Eberhardt; Lillian McMahon; Stephen J Duffy; Martin H Steinberg; Susan P Perrine; Joseph Loscalzo; Jay D Coffman; Joseph A Vita
Sickle cell anemia is associated with reduced nitric oxide bioactivity in peripheral conduit and resistance vessels.
American journal of hematology 2003;74(2):104-11.
2003: Michael E Widlansky; Daniel T Price; Noyan Gokce; Robert T Eberhardt; Stephen J Duffy; Monika Holbrook; Carolyn Maxwell; Joseph Palmisano; John F Keaney; Jason D Morrow; Joseph A Vita
Short- and long-term COX-2 inhibition reverses endothelial dysfunction in patients with hypertension.
Hypertension 2003;42(3):310-5.
2003: Salomon Amar; Noyan Gokce; Sonia Morgan; Mariana Loukideli; Thomas E Van Dyke; Joseph A Vita
Periodontal disease is associated with brachial artery endothelial dysfunction and systemic inflammation.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(7):1245-9.
2003: Noyan Gokce; John F Keaney; Liza M Hunter; Michael T Watkins; Zoran S Nedeljkovic; James O Menzoian; Joseph A Vita
Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events in patients with peripheral vascular disease.
Journal of the American College of Cardiology 2003;41(10):1769-75.
2003: Mehdi H Shishehbor; Ronnier J Aviles; Marie-Luise Brennan; Xiaoming Fu; Marlene Goormastic; Gregory Pearce; Noyan Gokce; John F Keaney; Marc S Penn; Dennis L Sprecher; Joseph A Vita; Stanley L Hazen
Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy.
JAMA : the journal of the American Medical Association 2003;289(13):1675-80.
2003: Joseph A Vita; Noyan Gokce; Stephen J Duffy; David Kahn; Douglas Tomasian; Joseph Palmisano; Shane Thomas; Monika Holbrook; John F Keaney
Effect of atorvastatin on endothelium-dependent vasodilation in patients with coronary artery disease.
The American journal of cardiology 2003;91(7):857-60.
2003: Jeffrey T Kuvin; Noyan Gokce; Monika Holbrook; Liza M Hunter; Ayan R Patel; Kathleen A Sliney; Donald E Craven; J Thomas Grayston; John F Keaney; Richard H Karas; Joseph A Vita
Effect of short-term antibiotic treatment on Chlamydia pneumoniae and peripheral endothelial function.
The American journal of cardiology 2003;91(6):732-5.
2003: John F Keaney; Martin G Larson; Ramachandran S Vasan; Peter W F Wilson; Izabella Lipinska; Diane Corey; Joseph M Massaro; Patrice Sutherland; Joseph A Vita; Emelia Benjamin
Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(3):434-9.
2002: Noyan Gokce; Monika Holbrook; Liza M Hunter; Joseph Palmisano; Elena Vigalok; John F Keaney; Joseph A Vita
Acute effects of vasoactive drug treatment on brachial artery reactivity.
Journal of the American College of Cardiology 2002;40(4):761-5.
2002: David F Kahn; Stephen J Duffy; Douglas Tomasian; Monika Holbrook; Lynn Rescorl; Judson Russell; Noyan Gokce; Joseph Loscalzo; Joseph A Vita
Effects of black race on forearm resistance vessel function.
Hypertension 2002;40(2):195-201.
2002: Noyan Gokce; Joseph A Vita; David S Bader; Debra L Sherman; Liza M Hunter; Monika Holbrook; Carol J O'Malley; John F Keaney; Gary J Balady
Effect of exercise on upper and lower extremity endothelial function in patients with coronary artery disease.
The American journal of cardiology 2002;90(2):124-7.
2002: John F Keaney; Joseph A Vita
Vascular oxidative stress and antioxidant protection in atherosclerosis: what do the clinical trials say?
Journal of cardiopulmonary rehabilitation 2002;22(4):225-33.
2002: Noyan Gokce; John F Keaney; Liza M Hunter; Michael T Watkins; James O Menzoian; Joseph A Vita
Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study.
Circulation 2002;105(13):1567-72.
2002: Joseph A Vita
Nitric oxide-dependent vasodilation in human subjects.
Methods in enzymology 2002;359():186-200.
2001: Noyan Gokce; Monika Holbrook; Stephen J Duffy; Serkalem Demissie; L Adrienne Cupples; Elizabeth S Biegelsen; John F Keaney; Joseph Loscalzo; Joseph A Vita
Effects of race and hypertension on flow-mediated and nitroglycerin-mediated dilation of the brachial artery.
Hypertension 2001;38(6):1349-54.
2001: Noyan Gokce; Stephen J Duffy; Liza M Hunter; John F Keaney; Joseph A Vita
Acute hypertriglyceridemia is associated with peripheral vasodilation and increased basal flow in healthy young adults.
The American journal of cardiology 2001;88(2):153-9.
2001: Stephen J Duffy; John F Keaney; Monika Holbrook; Noyan Gokce; P L Swerdloff; Balz Frei; Joseph A Vita
Short- and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease.
Circulation 2001;104(2):151-6.
2001: Stephen J Duffy; Elizabeth S Biegelsen; Monika Holbrook; J D Russell; Noyan Gokce; John F Keaney; Joseph A Vita
Iron chelation improves endothelial function in patients with coronary artery disease.
Circulation 2001;103(23):2799-804.
2001: Stephen J Duffy; Joseph A Vita; Monika Holbrook; P L Swerdloff; John F Keaney
Effect of acute and chronic tea consumption on platelet aggregation in patients with coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(6):1084-9.
2001: Kai Chen; Joseph A Vita; B C Berk; John F Keaney
c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.
The Journal of biological chemistry 2001;276(19):16045-50.
2001: Stephen J Duffy; Noyan Gokce; Monika Holbrook; Liza M Hunter; Elizabeth S Biegelsen; A Huang; John F Keaney; Joseph A Vita
Effect of ascorbic acid treatment on conduit vessel endothelial dysfunction in patients with hypertension.
American journal of physiology. Heart and circulatory physiology 2001;280(2):H528-34.
2000: Oz M Shapira; Joseph D Alkon; D S Macron; John F Keaney; Joseph A Vita; Gabriel S Aldea; Richard J Shemin
Nitroglycerin is preferable to diltiazem for prevention of coronary bypass conduit spasm.
The Annals of thoracic surgery 2000;70(3):883-8; discussion 888-9.
2000: Joseph A Vita; A C Yeung; M Winniford; J M Hodgson; C B Treasure; J L Klein; S Werns; M Kern; Diane J Plotkin; W J Shih; Yale B Mitchel; Peter Ganz
Effect of cholesterol-lowering therapy on coronary endothelial vasomotor function in patients with coronary artery disease.
Circulation 2000;102(8):846-51.
2000: Douglas Tomasian; John F Keaney; Joseph A Vita
Antioxidants and the bioactivity of endothelium-derived nitric oxide.
Cardiovascular research 2000;47(3):426-35.
2000: A Xu; Joseph A Vita; John F Keaney
Ascorbic acid and glutathione modulate the biological activity of S-nitrosoglutathione.
Hypertension 2000;36(2):291-5.
2000: Annong Huang; Joseph A Vita; Richard C Venema; John F Keaney
Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin.
The Journal of biological chemistry 2000;275(23):17399-406.
2000: Debra L Sherman; John F Keaney; Elizabeth S Biegelsen; Stephen J Duffy; Jay D Coffman; Joseph A Vita
Pharmacological concentrations of ascorbic acid are required for the beneficial effect on endothelial vasomotor function in hypertension.
Hypertension 2000;35(4):936-41.
2000: Daniel T Price; Joseph A Vita; John F Keaney
Redox control of vascular nitric oxide bioavailability.
Antioxidants & redox signaling 2000;2(4):919-35.
1999: Oz M Shapira; A Xu; Gabriel S Aldea; Joseph A Vita; Richard J Shemin; John F Keaney
Enhanced nitric oxide-mediated vascular relaxation in radial artery compared with internal mammary artery or saphenous vein.
Circulation 1999;100(19 Suppl):II322-7.
1999: Luc Djoussé; R Curtis Ellison; Christine E McLennan; L Adrienne Cupples; Izabella Lipinska; Geoffrey H Tofler; Noyan Gokce; Joseph A Vita
Acute effects of a high-fat meal with and without red wine on endothelial function in healthy subjects.
The American journal of cardiology 1999;84(6):660-4.
1999: Noyan Gokce; John F Keaney; Balz Frei; Monika Holbrook; M Olesiak; B J Zachariah; C Leeuwenburgh; J W Heinecke; Joseph A Vita
Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease.
Circulation 1999;99(25):3234-40.
1999: Oz M Shapira; A Xu; Joseph A Vita; Gabriel S Aldea; N Shah; Richard J Shemin; John F Keaney
Nitroglycerin is superior to diltiazem as a coronary bypass conduit vasodilator.
The Journal of thoracic and cardiovascular surgery 1999;117(5):906-11.
1999: A Ceriello; John F Keaney; Joseph A Vita
Vitamin C and endothelial dysfunction: what is new?
Circulation 1999;99(9):1273-4.
1998: Harold L Lazar; C Volpe; Yusheng Bao; Samuel Rivers; Joseph A Vita; John F Keaney
Beneficial effects of angiotensin-converting enzyme inhibitors during acute revascularization.
The Annals of thoracic surgery 1998;66(2):487-92.
1998: GT Shwaery; Joseph A Vita; John F Keaney
Antioxidant protection of LDL by physiologic concentrations of estrogens is specific for 17-beta-estradiol.
Atherosclerosis 1998;138(2):255-62.
1998: Joseph A Vita; John F Keaney; K E Raby; J D Morrow; Jane E Freedman; S Lynch; S N Koulouris; B R Hankin; Balz Frei
Low plasma ascorbic acid independently predicts the presence of an unstable coronary syndrome.
Journal of the American College of Cardiology 1998;31(5):980-6.
1998: Joseph A Vita; Balz Frei; Monika Holbrook; Noyan Gokce; C Leaf; John F Keaney
L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease.
The Journal of clinical investigation 1998;101(6):1408-14.
1998: T C Mannion; Joseph A Vita; John F Keaney; Emelia Benjamin; L Hunter; Joseph F Polak
Non-invasive assessment of brachial artery endothelial vasomotor function: the effect of cuff position on level of discomfort and vasomotor responses.
Vascular medicine (London, England) 1998;3(4):263-7.
1998: S Charo; Noyan Gokce; Joseph A Vita
Endothelial dysfunction and coronary risk reduction.
Journal of cardiopulmonary rehabilitation 1998;18(1):60-7.
1997: S M Lynch; Balz Frei; J D Morrow; L J Roberts; A Xu; T Jackson; R Reyna; L M Klevay; Joseph A Vita; John F Keaney
Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):2975-81.
1997: M N Diaz; B Frei; Joseph A Vita; John F Keaney
Antioxidants and atherosclerotic heart disease.
The New England journal of medicine 1997;337(6):408-16.
1997: GT Shwaery; Joseph A Vita; John F Keaney
Antioxidant protection of LDL by physiological concentrations of 17 beta-estradiol. Requirement for estradiol modification.
Circulation 1997;95(6):1378-85.
1996: John F Keaney; Y Guo; D Cunningham; GT Shwaery; A Xu; Joseph A Vita
Vascular incorporation of alpha-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation.
The Journal of clinical investigation 1996;98(2):386-94.
1996: J E Burchenal; John F Keaney; J Curran-Celentano; J Michael Gaziano; Joseph A Vita
The lack of effect of beta-carotene on restenosis in cholesterol-fed rabbits.
Atherosclerosis 1996;123(1-2):157-67.
1996: G N Levine; B Frei; S N Koulouris; M D Gerhard; John F Keaney; Joseph A Vita
Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease.
Circulation 1996;93(6):1107-13.
1995: D S Marks; Joseph A Vita; J D Folts; John F Keaney; GN Welch; Joseph Loscalzo
Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide.
The Journal of clinical investigation 1995;96(6):2630-8.
1995: John F Keaney; Joseph A Vita
Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action.
Progress in cardiovascular diseases 1995;38(2):129-54.
1995: John F Keaney; A Xu; D Cunningham; T Jackson; B Frei; Joseph A Vita
Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation.
The Journal of clinical investigation 1995;95(6):2520-9.
1995: G N Levine; John F Keaney; Joseph A Vita
Cholesterol reduction in cardiovascular disease. Clinical benefits and possible mechanisms.
The New England journal of medicine 1995;332(8):512-21.
1994: J S Scharfstein; John F Keaney; A Slivka; GN Welch; Joseph A Vita; Jonathan S Stamler; Joseph Loscalzo
In vivo transfer of nitric oxide between a plasma protein-bound reservoir and low molecular weight thiols.
The Journal of clinical investigation 1994;94(4):1432-9.
1994: John F Keaney; GT Shwaery; A Xu; Robert J Nicolosi; Joseph Loscalzo; T L Foxall; Joseph A Vita
17 beta-estradiol preserves endothelial vasodilator function and limits low-density lipoprotein oxidation in hypercholesterolemic swine.
Circulation 1994;89(5):2251-9.
1994: John F Keaney; J Michael Gaziano; A Xu; B Frei; J Curran-Celentano; GT Shwaery; Joseph Loscalzo; Joseph A Vita
Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.
The Journal of clinical investigation 1994;93(2):844-51.
1993: John F Keaney; J Michael Gaziano; A Xu; B Frei; J Curran-Celentano; GT Shwaery; Joseph Loscalzo; Joseph A Vita
Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11880-4.
1993: K E Raby; Joseph A Vita; M B Rocco; Alan C Yeung; P Ganz; G Fantasia; J Barry; Andrew P Selwyn
Changing vasomotor responses of coronary arteries to nifedipine.
American heart journal 1993;126(2):333-8.
1993: John F Keaney; Daniel I Simon; Jonathan S Stamler; O Jaraki; J Scharfstein; Joseph A Vita; Joseph Loscalzo
NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties.
The Journal of clinical investigation 1993;91(4):1582-9.
1993: C B Treasure; J Larry Klein; Joseph A Vita; S V Manoukian; G H Renwick; Andrew P Selwyn; P Ganz; Wayne R Alexander
Hypertension and left ventricular hypertrophy are associated with impaired endothelium-mediated relaxation in human coronary resistance vessels.
Circulation 1993;87(1):86-93.
1992: C B Treasure; S V Manoukian; J Larry Klein; Joseph A Vita; Elizabeth G Nabel; G H Renwick; Andrew P Selwyn; Wayne R Alexander; P Ganz
Epicardial coronary artery responses to acetylcholine are impaired in hypertensive patients.
Circulation research 1992;71(4):776-81.
1992: C B Treasure; Joseph A Vita; P Ganz; T J Ryan; Frederick J Schoen; V I Vekshtein; Alan C Yeung; G H Mudge; Wayne R Alexander; Andrew P Selwyn
Loss of the coronary microvascular response to acetylcholine in cardiac transplant patients.
Circulation 1992;86(4):1156-64.
1992: Jonathan S Stamler; O Jaraki; J Osborne; Daniel I Simon; John F Keaney; Joseph A Vita; D Singel; C R Valeri; Joseph Loscalzo
Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7674-7.
1992: Joseph A Vita; C B Treasure; Alan C Yeung; V I Vekshtein; G M Fantasia; R D Fish; P Ganz; Andrew P Selwyn
Patients with evidence of coronary endothelial dysfunction as assessed by acetylcholine infusion demonstrate marked increase in sensitivity to constrictor effects of catecholamines.
Circulation 1992;85(4):1390-7.
1991: Alan C Yeung; V I Vekshtein; D S Krantz; Joseph A Vita; T J Ryan; P Ganz; Andrew P Selwyn
The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress.
The New England journal of medicine 1991;325(22):1551-6.
1991: P Ganz; Franz Weidinger; Alan C Yeung; V I Vekshtein; Joseph A Vita; T J Ryan; J M McLenachan; Andrew P Selwyn
Coronary vasospasm in humans: the role of atherosclerosis and of impaired endothelial vasodilator function.
Basic research in cardiology 1991;86 Suppl 2():215-22.
1991: Andrew P Selwyn; K Raby; Joseph A Vita; P Ganz; A Yeung
Diurnal rhythms and clinical events in coronary artery disease.
Postgraduate medical journal 1991;67 Suppl 5():S44-7.
1990: J M McLenachan; Joseph A Vita; D R Fish; C B Treasure; D A Cox; P Ganz; Andrew P Selwyn
Early evidence of endothelial vasodilator dysfunction at coronary branch points.
Circulation 1990;82(4):1169-73.
1990: C B Treasure; Joseph A Vita; D A Cox; R D Fish; John B Gordon; G H Mudge; Wilson S Colucci; Martin G St John Sutton; Andrew P Selwyn; Wayne R Alexander
Endothelium-dependent dilation of the coronary microvasculature is impaired in dilated cardiomyopathy.
Circulation 1990;81(3):772-9.
1990: Joseph A Vita; C B Treasure; Elizabeth G Nabel; J M McLenachan; R D Fish; Alan C Yeung; V I Vekshtein; Andrew P Selwyn; P Ganz
Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease.
Circulation 1990;81(2):491-7.
1990: C B Treasure; Joseph A Vita; D A Cox; R D Fish; Andrew P Selwyn; Wayne R Alexander; P Ganz
Acute myocardial infarction with normal coronary arteries associated with acetylcholine-induced vasoconstriction in the absence of a positive ergonovine test.
The American journal of cardiology 1990;65(3):255-7.
1990: Andrew P Selwyn; Joseph A Vita; V I Vekshtein; A Yeung; T Ryan; P Ganz
Myocardial ischemia: pathogenic role of disturbed vasomotion and endothelial dysfunction in coronary atherosclerosis.
Advances in cardiology 1990;37():42-52.
1989: Joseph A Vita; C B Treasure; P Ganz; D A Cox; R D Fish; Andrew P Selwyn
Control of shear stress in the epicardial coronary arteries of humans: impairment by atherosclerosis.
Journal of the American College of Cardiology 1989;14(5):1193-9.
1989: D A Cox; Joseph A Vita; C B Treasure; R D Fish; Wayne R Alexander; P Ganz; Andrew P Selwyn
Atherosclerosis impairs flow-mediated dilation of coronary arteries in humans.
Circulation 1989;80(3):458-65.
1989: D A Cox; Joseph A Vita; C B Treasure; R D Fish; Andrew P Selwyn; P Ganz
Reflex increase in blood pressure during the intracoronary administration of adenosine in man.
The Journal of clinical investigation 1989;84(2):592-6.
1989: Joseph A Vita; Peter L Friedman; C Cantillon; Elliott M Antman
Efficacy of intravenous propafenone for the acute management of atrial fibrillation.
The American journal of cardiology 1989;63(17):1275-8.
1988: Joseph A Vita; John A Bittl; Andrew P Selwyn; J E Lock
Transcatheter closure of a calcified patent ductus arteriosus in an elderly man.
Journal of the American College of Cardiology 1988;12(5):1382-5.
1985: Elsa-Grace V Giardina; K Raby; D Freilich; Joseph A Vita; Rachel F. Brem; M Louie
Time course of alpha-1-acid glycoprotein and its relation to myocardial enzymes after acute myocardial infarction.
The American journal of cardiology 1985;56(4):262-5.
1985: Elsa-Grace V Giardina; Lynne L Johnson; Joseph A Vita; J Thomas Bigger; Rachel F. Brem
Effect of imipramine and nortriptyline on left ventricular function and blood pressure in patients treated for arrhythmias.
American heart journal 1985;109(5 Pt 1):992-8.