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Martha Hotz Vitaterna

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Kazuhiro Shimomura; Martha Hotz Vitaterna; A Whiteley; Tim Wiltshire; Seung-Hee Yoo; Joseph Bass; Ethan D Buhr; Jason Chong; Deborah Fenner; John Hogenesch; Hee-Kyung Hong; Tae-Kyung Kim; Nobuya Koike; Vivek Kumar; Sharon S Low; Phillip L Lowrey; Chiaki Omura; Joseph R Owens; Mathew T Pletcher; Marc Richards; Joseph S Takahashi
Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice.
Keith C Summa; Martha Hotz Vitaterna; Fred W Turek
Environmental perturbation of the circadian clock disrupts pregnancy in the mouse.
Deborah Fenner; Joseph Grimsby; Hee-Kyung Hong; Yumiko Kobayashi; Akira Kohsaka; Franz M Matschinsky; Stella Odili; Sandra M Siepka; Joseph S Takahashi; Martha Hotz Vitaterna; Bogumil Zelent; Pan Chen; Joseph Bass
Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators.

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All Publications

2013: Kazuhiro Shimomura; Martha Hotz Vitaterna; A Whiteley; Tim Wiltshire; Seung-Hee Yoo; Joseph Bass; Ethan D Buhr; Jason Chong; Deborah Fenner; John Hogenesch; Hee-Kyung Hong; Tae-Kyung Kim; Nobuya Koike; Vivek Kumar; Sharon S Low; Phillip L Lowrey; Chiaki Omura; Joseph R Owens; Mathew T Pletcher; Marc Richards; Joseph S Takahashi
Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice.
eLife 2013;2():e00426.
2012: Keith C Summa; Martha Hotz Vitaterna; Fred W Turek
Environmental perturbation of the circadian clock disrupts pregnancy in the mouse.
PloS one 2012;7(5):e37668.
2011: Deborah Fenner; Joseph Grimsby; Hee-Kyung Hong; Yumiko Kobayashi; Akira Kohsaka; Franz M Matschinsky; Stella Odili; Sandra M Siepka; Joseph S Takahashi; Martha Hotz Vitaterna; Bogumil Zelent; Pan Chen; Joseph Bass
Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators.
The Journal of biological chemistry 2011;286(45):39560-72.
2011: Deanna Marie Arble; Martha Hotz Vitaterna; Fred W Turek
Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouse.
PloS one 2011;6(9):e25079.
2011: Fred W Turek; Martha Hotz Vitaterna
Molecular neurobiology of circadian rhythms.
Handbook of clinical neurology 2011;99():951-61.
2010: Kazuhiro Shimomura; Phillip L Lowrey; Martha Hotz Vitaterna; Ethan D Buhr; Vivek Kumar; Peter Hanna; Chiaki Omura; Mariko Izumo; Sharon S Low; R Keith Barrett; Silvia I LaRue; Carla B Green; Joseph S Takahashi
Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(18):8399-403.
2009: Deanna M Arble; Joseph Bass; Aaron D Laposky; Martha Hotz Vitaterna; Fred W Turek
Circadian timing of food intake contributes to weight gain.
Obesity (Silver Spring, Md.) 2009;17(11):2100-2.
2009: He S Yang; Martha Hotz Vitaterna; Aaron D Laposky; Kazuhiro Shimomura; Fred W Turek
Genetic analysis of daily physical activity using a mouse chromosome substitution strain.
Physiological genomics 2009;39(1):47-55.
2007: Kole Roybal; David Theobold; Ami Graham; Jennifer A DiNieri; Scott J Russo; Vaishnav Krishnan; Sumana Chakravarty; Joseph Peevey; Nathan Oehrlein; Shari Birnbaum; Martha Hotz Vitaterna; Paul Orsulak; Joseph S Takahashi; Eric J Nestler; William A Carlezon; Colleen A McClung
Mania-like behavior induced by disruption of CLOCK.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6406-11.
2007: Lawrence H Pinto; Martha Hotz Vitaterna; Kazuhiro Shimomura; Sandra M Siepka; Victoria Balannik; Erin L McDearmon; Chiaki Omura; Stephen Lumayag; Brandon M Invergo; Brett Glawe; Donald R Cantrell; Samsoon Inayat; Marissa A Olvera; Kirstan A Vessey; Maureen A McCall; Dennis Maddox; Catherine W Morgans; Brandon Young; Mathew Pletcher; robert Mullins; John B Troy; Joseph S Takahashi
Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse.
Visual neuroscience 2007;24(1):111-23.
2006: Martha Hotz Vitaterna; Caroline Ko; Anne-Marie Chang; Ethan D Buhr; Ethan M Fruechte; Andrew Schook; Marina P Antoch; Fred W Turek; Joseph S Takahashi
The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9327-32.
2006: Martha Hotz Vitaterna; Lawrence H Pinto; Joseph S Takahashi
Large-scale mutagenesis and phenotypic screens for the nervous system and behavior in mice.
Trends in neurosciences 2006;29(4):233-40.
2006: Jennifer L Moran; Andrew D Bolton; Pamela V Tran; Alison Brown; Noelle D Dwyer; Danielle K Manning; Bryan Bjork; Cheng Li; Kate Montgomery; Sandra M Siepka; Martha Hotz Vitaterna; Joseph S Takahashi; Timothy Wiltshire; David J Kwiatkowski; Raju Kucherlapati; David Beier
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.
Genome research 2006;16(3):436-40.
2005: Lawrence H Pinto; Martha Hotz Vitaterna; Kazuhiro Shimomura; Sandra M Siepka; Erin L McDearmon; Deborah Fenner; Stephen Lumayag; Chiaki Omura; Anne W Andrews; Matthew Baker; Brandon M Invergo; Marissa A Olvera; Edward Heffron; robert Mullins; Val C Sheffield; Edwin M Stone; Joseph S Takahashi
Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse.
Visual neuroscience 2005;22(5):619-29.
2005: Joseph A Brzezinski; Nadean L Brown; Atsuhiro Tanikawa; Ronald A Bush; Paul Sieving; Martha Hotz Vitaterna; Joseph S Takahashi; Thomas M Glaser
Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice.
Investigative ophthalmology & visual science 2005;46(7):2540-51.
2005: Colleen A McClung; Kyriaki Sidiropoulou; Martha Hotz Vitaterna; Joseph S Takahashi; Francis J White; Donald C Cooper; Eric J Nestler
Regulation of dopaminergic transmission and cocaine reward by the Clock gene.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9377-81.
2004: Lawrence H Pinto; Martha Hotz Vitaterna; Sandra M Siepka; Kazuhiro Shimomura; Stephen Lumayag; Matthew Baker; Deborah Fenner; robert Mullins; Val C Sheffield; Edwin M Stone; Edward Heffron; Joseph S Takahashi
Results from screening over 9000 mutation-bearing mice for defects in the electroretinogram and appearance of the fundus.
Vision research 2004;44(28):3335-45.
2004: Amander T Clark; Dan Goldowitz; Joseph S Takahashi; Martha Hotz Vitaterna; Sandra M Siepka; Luanne L Peters; Wayne N Frankel; George A Carlson; Janet Rossant; Joseph H Nadeau; Monica J Justice
Implementing large-scale ENU mutagenesis screens in North America.
Genetica 2004;122(1):51-64.
2004: Carol Bult; Warren Kibbe; Jay Snoddy; Martha Hotz Vitaterna; Doug Swanson; Stephanie Pretel; Yanxia Li; Moses M Hohman; Eugene Rinchik; Joseph S Takahashi; Wayne N Frankel; Dan Goldowitz
A genome end-game: understanding gene function in the nervous system.
Nature neuroscience 2004;7(5):484-5.
2004: Daniel E Kolker; Martha Hotz Vitaterna; Ethan M Fruechte; Joseph S Takahashi; Fred W Turek
Effects of age on circadian rhythms are similar in wild-type and heterozygous Clock mutant mice.
Neurobiology of aging 2004;25(4):517-23.
2001: Kazuhiro Shimomura; Sharon S Low; DP King; TD Steeves; A Whiteley; J Kushla; P D Zemenides; A Lin; Martha Hotz Vitaterna; Gary Churchill; Joseph S Takahashi
Genome-wide epistatic interaction analysis reveals complex genetic determinants of circadian behavior in mice.
Genome research 2001;11(6):959-80.
2001: Martha Hotz Vitaterna; Joseph S Takahashi; Fred W Turek
Overview of circadian rhythms.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 2001;25(2):85-93.
2000: Elizabeth M Naylor; Bernard M Bergmann; K Krauski; Phyllis C Zee; Joseph S Takahashi; Martha Hotz Vitaterna; Fred W Turek
The circadian clock mutation alters sleep homeostasis in the mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(21):8138-43.
1999: Martha Hotz Vitaterna; Christopher P Selby; T Todo; H Niwa; Carol Thompson; Ethan M Fruechte; K Hitomi; Randy J Thresher; T Ishikawa; J Miyazaki; Joseph S Takahashi; Aziz Sancar
Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):12114-9.
1998: Randy J Thresher; Martha Hotz Vitaterna; Y Miyamoto; A Kazantsev; DS Hsu; C Petit; Christopher P Selby; L Dawut; Oliver Smithies; Joseph S Takahashi; Aziz Sancar
Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.
Science (New York, N.Y.) 1998;282(5393):1490-4.
1998: AM Sangoram; Lino Saez; Marina P Antoch; Nicholas Gekakis; David Staknis; A Whiteley; Ethan M Fruechte; Martha Hotz Vitaterna; Kazuhiro Shimomura; D P King; Michael W Young; Charles J Weitz; Joseph S Takahashi
Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.
Neuron 1998;21(5):1101-13.
1998: VS Valentinuzzi; Daniel E Kolker; Martha Hotz Vitaterna; Kazuhiro Shimomura; A Whiteley; Sharon S Low; Fred W Turek; EA Ferrari; R Paylor; Joseph S Takahashi
Automated measurement of mouse freezing behavior and its use for quantitative trait locus analysis of contextual fear conditioning in (BALB/cJ x C57BL/6J)F2 mice.
Learning & memory (Cold Spring Harbor, N.Y.) 1998;5(4-5):391-403.
1997: T Porkka-Heiskanen; N Khoshaba; K Scarbrough; Janice H Urban; Martha Hotz Vitaterna; Jon E Levine; Fred W Turek; Teresa H Horton
Rapid photoperiod-induced increase in detectable GnRH mRNA-containing cells in Siberian hamster.
The American journal of physiology 1997;273(6 Pt 2):R2032-9.
1997: DP King; Martha Hotz Vitaterna; Anne-Marie Chang; W F Dove; Lawrence H Pinto; Fred W Turek; Joseph S Takahashi
The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit.
Genetics 1997;146(3):1049-60.
1997: Marina P Antoch; Eun-joo Song; Anne-Marie Chang; Martha Hotz Vitaterna; Y Zhao; Lisa D Wilsbacher; AM Sangoram; DP King; Lawrence H Pinto; Joseph S Takahashi
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
Cell 1997;89(4):655-67.
1997: DP King; Y Zhao; AM Sangoram; Lisa D Wilsbacher; M Tanaka; Marina P Antoch; TD Steeves; Martha Hotz Vitaterna; JM Kornhauser; Phillip L Lowrey; Fred W Turek; Joseph S Takahashi
Positional cloning of the mouse circadian clock gene.
Cell 1997;89(4):641-53.
1995: Fred W Turek; Lawrence H Pinto; Martha Hotz Vitaterna; PD Penev; Phyllis C Zee; Joseph S Takahashi
Pharmacological and genetic approaches for the study of circadian rhythms in mammals.
Frontiers in neuroendocrinology 1995;16(3):191-223.
1994: Joseph S Takahashi; Lawrence H Pinto; Martha Hotz Vitaterna
Forward and reverse genetic approaches to behavior in the mouse.
Science (New York, N.Y.) 1994;264(5166):1724-33.
1994: Martha Hotz Vitaterna; DP King; Anne-Marie Chang; Jon M Kornhauser; P L Lowrey; J D McDonald; William F Dove; Lawrence H Pinto; Fred W Turek; Joseph S Takahashi
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior.
Science (New York, N.Y.) 1994;264(5159):719-25.
1993: Martha Hotz Vitaterna; Fred W Turek
Photoperiodic responses differ among inbred strains of golden hamsters (Mesocricetus auratus).
Biology of reproduction 1993;49(3):496-501.
1993: Martha Hotz Vitaterna; J C Wu; Fred W Turek; Lawrence H Pinto
Reduced light sensitivity of the circadian clock in a hypopigmented mouse mutant.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1993;95(3):436-42.