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Ellen Vitetta

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Peter C Isakson; Ellen Puré; Ellen S Vitetta; Peter H Krammer
Pillars article: T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells. J. Exp. Med. 1982. 155: 734-748.
Shihong Ma; Andrew BitMansour; Rajesh Pidikiti; James A Richardson; Timothy D Solberg; Kwang Song; Strahinja Stojadinovic; Ellen S Vitetta; Jeffrey J Meyer
Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation.
Ellen S Vitetta; Joan E Smallshaw; John Schindler
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.

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2013: Peter C Isakson; Ellen Puré; Ellen S Vitetta; Peter H Krammer
Pillars article: T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells. J. Exp. Med. 1982. 155: 734-748.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(3):849-63.
2013: Shihong Ma; Andrew BitMansour; Rajesh Pidikiti; James A Richardson; Timothy D Solberg; Kwang Song; Strahinja Stojadinovic; Ellen S Vitetta; Jeffrey J Meyer
Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation.
PloS one 2013;8(2):e56607.
2012: Ellen S Vitetta; Joan E Smallshaw; John Schindler
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
Clinical and vaccine immunology : CVI 2012;19(10):1697-9.
2012: Megan B Wachsmann; Laurentiu M Pop; Ellen S Vitetta
Pancreatic ductal adenocarcinoma: a review of immunologic aspects.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2012;60(4):643-63.
2012: Xiao-yun Liu; Laurentiu M Pop; John Schindler; Ellen S Vitetta
Immunotoxins constructed with chimeric, short-lived anti-CD22 monoclonal antibodies induce less vascular leak without loss of cytotoxicity.
mAbs 2012;4(1):57-68.
2012: Joan E Smallshaw; Ellen S Vitetta
Ricin vaccine development.
Current topics in microbiology and immunology 2012;357():259-72.
2011: Seth H Pincus; Joan E Smallshaw; Kejing Song; Jody Berry; Ellen S Vitetta
Passive and active vaccination strategies to prevent ricin poisoning.
Toxins 2011;3(9):1163-84.
2011: Patricia M Legler; Joan E Smallshaw; Ellen S Vitetta; Robert N Brey; Charles B Millard
Structure of RiVax: a recombinant ricin vaccine.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 9):826-30.
2011: Xiao-Yun Liu; Iliodora V Pop; Laurentiu M Pop; Lydia Tsai; Ellen S Vitetta
Chimeric, divalent and tetravalent anti-CD19 monoclonal antibodies with potent in vitro and in vivo antitumor activity against human B-cell lymphoma and pre-B acute lymphoblastic leukemia cell lines.
International journal of cancer. Journal international du cancer 2011;129(2):497-506.
2011: Lydia K Tsai; Xiaoyun Liu; Laurentiu M Pop; Ellen S Vitetta
A comparison of the anti-tumor effects of a chimeric versus murine anti-CD19 immunotoxins on human B cell lymphoma and Pre-B acute lymphoblastic leukemia cell lines.
Toxins 2011;3(4):409-19.
2011: Radu Marches; Carole Mikoryak; Ru-Hung Wang; Paul Pantano; Rockford K Draper; Ellen S Vitetta
The importance of cellular internalization of antibody-targeted carbon nanotubes in the photothermal ablation of breast cancer cells.
Nanotechnology 2011;22(9):095101.
2010: Praveena S Marconescu; Joan E Smallshaw; Laurentiu M Pop; Stephen L Ruback; Ellen S Vitetta
Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication.
Vaccine 2010;28(32):5315-22.
2010: Joan E Smallshaw; Ellen S Vitetta
A lyophilized formulation of RiVax, a recombinant ricin subunit vaccine, retains immunogenicity.
Vaccine 2010;28(12):2428-35.
2009: Radu Marches; Pavitra Chakravarty; Inga H Musselman; Pooja Bajaj; Robert N Azad; Paul Pantano; Rockford K Draper; Ellen S Vitetta
Specific thermal ablation of tumor cells using single-walled carbon nanotubes targeted by covalently-coupled monoclonal antibodies.
International journal of cancer. Journal international du cancer 2009;125(12):2970-7.
2009: Larry Herrera; Bruce C Bostrom; Lisa Gore; Eric Sandler; Glen Lew; Paul G Schlegel; Victor Aquino; Victor Ghetie; Ellen S Vitetta; John Schindler
A phase 1 study of Combotox in pediatric patients with refractory B-lineage acute lymphoblastic leukemia.
Journal of pediatric hematology/oncology 2009;31(12):936-41.
2009: Iliodora V Pop; Laurentiu M Pop; Maria-Ana Ghetie; Ellen S Vitetta
Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines.
Leukemia & lymphoma 2009;50(7):1155-62.
2008: Kimberly J Brooks; Elaine J Coleman; Ellen S Vitetta
The antitumor activity of an anti-CD54 antibody in SCID mice xenografted with human breast, prostate, non-small cell lung, and pancreatic tumor cell lines.
International journal of cancer. Journal international du cancer 2008;123(10):2438-45.
2008: Pavitra Chakravarty; Radu Marches; Neil S Zimmerman; Austin D-E Swafford; Pooja Bajaj; Inga H Musselman; Paul Pantano; Rockford K Draper; Ellen S Vitetta
Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(25):8697-702.
2008: Xiao-yun Liu; Laurentiu M Pop; Ellen S Vitetta
Engineering therapeutic monoclonal antibodies.
Immunological reviews 2008;222():9-27.
2008: Iliodora Pop; Laurentiu Pop; Ellen S Vitetta; Maria-Ana Ghetie
Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein.
Oncology reports 2008;19(4):889-95.
2008: Daniel J Powell; Peter Attia; Victor Ghetie; John Schindler; Ellen S Vitetta; STEVEN ROSENBERG
Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(2):189-98.
2007: Joan E Smallshaw; James A Richardson; Ellen S Vitetta
RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosol.
Vaccine 2007;25(42):7459-69.
2007: Stephan Mielke; Katayoun Rezvani; Bipin N Savani; Raquel Nunes; Agnes S M Yong; John Schindler; Roger Kurlander; Victor Ghetie; Elizabeth J Read; Scott R Solomon; Ellen S Vitetta; A John Barrett
Reconstitution of FOXP3+ regulatory T cells (Tregs) after CD25-depleted allotransplantation in elderly patients and association with acute graft-versus-host disease.
Blood 2007;110(5):1689-97.
2007: Rosalia Rabinovsky; Jonathan Uhr; Ellen S Vitetta; Eitan Yefenof
Cancer dormancy: lessons from a B cell lymphoma and adenocarcinoma of the prostate.
Advances in cancer research 2007;97():189-202.
2006: L Herrera; C Stanciu-Herrera; C Morgan; Victor Ghetie; Ellen S Vitetta
Anti-CD19 immunotoxin enhances the activity of chemotherapy in severe combined immunodeficient mice with human pre-B acute lymphoblastic leukemia.
Leukemia & lymphoma 2006;47(11):2380-7.
2006: Persis J Amrolia; Giada Muccioli-Casadei; Helen Huls; Stuart Adams; April Durett; Adrian Gee; Eric Yvon; Heidi Weiss; Mark Cobbold; H Bobby Gaspar; Cliona Rooney; Ingrid Kuehnle; Victor Ghetie; John Schindler; Robert A Krance; Helen E Heslop; Paul Veys; Ellen S Vitetta; Malcolm K Brenner
Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation.
Blood 2006;108(6):1797-808.
2006: Maria-Ana Ghetie; Michelle Crank; Stephanie Kufert; Iliodora Pop; Ellen S Vitetta
Rituximab but not other anti-CD20 antibodies reverses multidrug resistance in 2 B lymphoma cell lines, blocks the activity of P-glycoprotein (P-gp), and induces P-gp to translocate out of lipid rafts.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(5):536-44.
2006: Elaine J Coleman; Kimberly J Brooks; Joan E Smallshaw; Ellen S Vitetta
The Fc portion of UV3, an anti-CD54 monoclonal antibody, is critical for its antitumor activity in SCID mice with human multiple myeloma or lymphoma cell lines.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(5):489-98.
2006: Ellen S Vitetta; Victor Ghetie
Immunology. Considering therapeutic antibodies.
Science (New York, N.Y.) 2006;313(5785):308-9.
2006: Xiao-Yun Liu; Laurentiu M Pop; Derry C Roopenian; Victor Ghetie; Ellen S Vitetta; Joan E Smallshaw
Generation and characterization of a novel tetravalent anti-CD22 antibody with improved antitumor activity and pharmacokinetics.
International immunopharmacology 2006;6(5):791-9.
2006: P Vaclavkova; Yanying Cao; L K Wu; J Michalek; Ellen S Vitetta
A comparison of an anti-CD25 immunotoxin, Ontak and anti-CD25 microbeads for their ability to deplete alloreactive T cells in vitro.
Bone marrow transplantation 2006;37(6):559-67.
2006: Shixuan Wang; Elaine J Coleman; Laurentiu M Pop; Kimberly J Brooks; Ellen S Vitetta; Jerry Y Niederkorn
Effect of an anti-CD54 (ICAM-1) monoclonal antibody (UV3) on the growth of human uveal melanoma cells transplanted heterotopically and orthotopically in SCID mice.
International journal of cancer. Journal international du cancer 2006;118(4):932-41.
2006: Ellen S Vitetta; Joan E Smallshaw; Elaine Coleman; Hasan Jafri; Callie Foster; Robert Munford; John Schindler
A pilot clinical trial of a recombinant ricin vaccine in normal humans.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2268-73.
2005: Laurentiu M Pop; Joan E Smallshaw; Thomas F Tucker; Freda K Stevenson; Ellen S Vitetta
Failure of vaccination with idiotypic protein or DNA, (+/-IL-2), the depletion of regulatory T cells, or the blockade of CTLA-4 to prolong dormancy in mice with BCL1 lymphoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2005;28(6):525-34.
2005: Joan E Smallshaw; James A Richardson; Seth Pincus; John Schindler; Ellen S Vitetta
Preclinical toxicity and efficacy testing of RiVax, a recombinant protein vaccine against ricin.
Vaccine 2005;23(39):4775-84.
2005: Scott R Solomon; Stephan Mielke; Bipin N Savani; Aldemar Montero; Laura Wisch; Richard Childs; Nancy Hensel; John Schindler; Victor Ghetie; Susan F Leitman; Thao Mai; Charles S Carter; Roger Kurlander; Elizabeth J Read; Ellen S Vitetta; A John Barrett
Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation.
Blood 2005;106(3):1123-9.
2005: Laurentiu M Pop; Xiaoyun Liu; Victor Ghetie; Ellen S Vitetta
The generation of immunotoxins using chimeric anti-CD22 antibodies containing mutations which alter their serum half-life.
International immunopharmacology 2005;5(7-8):1279-90.
2005: Persis J Amrolia; G Mucioli-Casadei; Helen Huls; Helen E Heslop; John Schindler; Paul Veys; Ellen S Vitetta; Malcolm K Brenner
Add-back of allodepleted donor T cells to improve immune reconstitution after haplo-identical stem cell transplantation.
Cytotherapy 2005;7(2):116-25.
2004: Joan E Smallshaw; Elaine Coleman; Camelia I Spiridon; Ellen S Vitetta
The generation and anti-myeloma activity of a chimeric anti-CD54 antibody, cUV3.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(6):419-24.
2004: Paul J Martin; Ji Pei; Ted Gooley; Claudio Anasetti; Frederick R Appelbaum; Joachim Deeg; John A Hansen; Richard A Nash; Effie W Petersdorf; Rainer Storb; Victor Ghetie; John Schindler; Ellen S Vitetta
Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(8):552-60.
2004: Jesús Saavedra-Lozano; Cynthia McCoig; Yanying Cao; Ellen S Vitetta; Octavio Ramilo
Zidovudine, lamivudine, and abacavir have different effects on resting cells infected with human immunodeficiency virus in vitro.
Antimicrobial agents and chemotherapy 2004;48(8):2825-30.
2004: Maria-Ana Ghetie; Radu Marches; Stephanie Kufert; Ellen S Vitetta
An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line.
Blood 2004;104(1):178-83.
2004: Songdong Meng; Debu Tripathy; Sanjay Shete; Raheela Ashfaq; Barbara B Haley; Steve Perkins; Peter D Beitsch; Amanullah Khan; David M Euhus; Cynthia Osborne; Eugene P Frenkel; Susan Hoover; Marilyn Leitch; Edward Clifford; Ellen S Vitetta; Larry Morrison; Dorothee Herlyn; Leon W M M Terstappen; Timothy Fleming; Tanja Fehm; Thomas Tucker; Nancy Lane; Jianqiang Wang; Jonathan Uhr
HER-2 gene amplification can be acquired as breast cancer progresses.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9393-8.
2004: Camelia I Spiridon; Sarah Guinn; Ellen S Vitetta
A comparison of the in vitro and in vivo activities of IgG and F(ab')2 fragments of a mixture of three monoclonal anti-Her-2 antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3542-51.
2004: Jesús Saavedra-Lozano; Yanying Cao; J Callison; Ravindra Sarode; Donald L Sodora; J Edgar; Jeanine Hatfield; Louis J Picker; D Peterson; Octavio Ramilo; Ellen S Vitetta
An anti-CD45RO immunotoxin kills HIV-latently infected cells from individuals on HAART with little effect on CD8 memory.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2494-9.
2004: Ruiqi Meng; Joan E Smallshaw; Laurentiu M Pop; Michael Yen; Xiaoyun Liu; Lien Le; Maria-Ana Ghetie; Ellen S Vitetta; Victor Ghetie
The evaluation of recombinant, chimeric, tetravalent antihuman CD22 antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(4):1274-81.
2003: Persis J Amrolia; Giada Muccioli-Casadei; Eric Yvon; Helen Huls; Uluhan Sili; Eric Wieder; Catherine M Bollard; Jaroslav Michalek; Victor Ghetie; Helen E Heslop; Jeffrey J Molldrem; Cliona M Rooney; John Schlinder; Ellen S Vitetta; Malcolm K Brenner
Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses.
Blood 2003;102(6):2292-9.
2003: Roland Schnell; Peter Borchmann; Jan Oliver Staak; John Schindler; Victor Ghetie; Ellen S Vitetta; Andreas Engert
Clinical evaluation of ricin A-chain immunotoxins in patients with Hodgkin's lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(5):729-36.
2003: Joan E Smallshaw; Victor Ghetie; Josep Rizo; John R Fulmer; Linda L Trahan; Maria-Ana Ghetie; Ellen S Vitetta
Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice.
Nature biotechnology 2003;21(4):387-91.
2003: J Michalek; Robert H Collins; H P Durrani; P Vaclavkova; Laura E Ruff; Daniel C Douek; Ellen S Vitetta
Definitive separation of graft-versus-leukemia- and graft-versus-host-specific CD4+ T cells by virtue of their receptor beta loci sequences.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1180-4.
2003: L Herrera; S Yarbrough; Victor Ghetie; DB Aquino; Ellen S Vitetta
Treatment of SCID/human B cell precursor ALL with anti-CD19 and anti-CD22 immunotoxins.
Leukemia 2003;17(2):334-8.
2003: Jaroslav Michálek; Robert H Collins; Ellen S Vitetta
Clinical-scale selective depletion of alloreactive T cells using an anti-CD25 immunotoxin.
Neoplasma 2003;50(4):296-9.
2002: Isabelle André-Schmutz; Françoise Le Deist; Salima Hacein-Bey; Yamina Hamel; Ellen S Vitetta; John Schindler; Alain Fischer; Marina Cavazzana-Calvo
Donor T lymphocyte infusion following ex vivo depletion of donor anti-host reactivity by a specific anti-interleukin-2 receptor P55 chain immunotoxin.
Transplantation proceedings 2002;34(7):2927-8.
2002: Joan E Smallshaw; Ana Firan; John R Fulmer; Stephen L Ruback; Victor Ghetie; Ellen S Vitetta
A novel recombinant vaccine which protects mice against ricin intoxication.
Vaccine 2002;20(27-28):3422-7.
2002: Isabelle André-Schmutz; Françoise Le Deist; Salima Hacein-Bey-Abina; Ellen S Vitetta; John Schindler; Gaëlle Chedeville; Etienne Vilmer; Alain Fischer; Marina Cavazzana-Calvo
Immune reconstitution without graft-versus-host disease after haemopoietic stem-cell transplantation: a phase 1/2 study.
Lancet 2002;360(9327):130-7.
2002: Roland Schnell; Oliver Staak; Peter Borchmann; Christine Schwartz; Bärbel Matthey; Hinrich Hansen; John Schindler; Victor Ghetie; Ellen S Vitetta; Volker Diehl; Andreas Engert
A Phase I study with an anti-CD30 ricin A-chain immunotoxin (Ki-4.dgA) in patients with refractory CD30+ Hodgkin's and non-Hodgkin's lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1779-86.
2002: Camelia I Spiridon; Maria-Ana Ghetie; Jonathan Uhr; Radu Marches; Jia-Ling Li; Guo-Liang Shen; Ellen S Vitetta
Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1720-30.
2002: Jesús Saavedra-Lozano; Cynthia McCoig; Jinbo Xu; Yanying Cao; Philip Keiser; Victor Ghetie; Robert Siliciano; Janet D Siliciano; Louis J Picker; Octavio Ramilo; Ellen S Vitetta
An anti-CD45RO immunotoxin kills latently infected human immunodeficiency virus (HIV) CD4 T cells in the blood of HIV-positive persons.
The Journal of infectious diseases 2002;185(3):306-14.
2002: Scott R Solomon; T Tran; Charles S Carter; S Donnelly; Nancy Hensel; John Schindler; Erkut Bahceci; Victor Ghetie; Jaroslav Michálek; DA Mavroudis; Elizabeth J Read; Ellen S Vitetta; A John Barrett
Optimized clinical-scale culture conditions for ex vivo selective depletion of host-reactive donor lymphocytes: a strategy for GvHD prophylaxis in allogeneic PBSC transplantation.
Cytotherapy 2002;4(5):395-406.
2001: Victor Ghetie; Ellen S Vitetta
Chemical construction of immunotoxins.
Molecular biotechnology 2001;18(3):251-68.
2001: Radu Marches; Ellen S Vitetta; Jonathan Uhr
A role for intracellular pH in membrane IgM-mediated cell death of human B lymphomas.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3434-9.
2001: Maria-Ana Ghetie; H Bright; Ellen S Vitetta
Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin.
Blood 2001;97(5):1392-8.
2001: J Schindler; Edward A Sausville; Richard A Messmann; Jonathan Uhr; Ellen S Vitetta
The toxicity of deglycosylated ricin A chain-containing immunotoxins in patients with non-Hodgkin's lymphoma is exacerbated by prior radiotherapy: a retrospective analysis of patients in five clinical trials.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(2):255-8.
2000: R Baluna; Elaine Coleman; C Jones; Victor Ghetie; Ellen S Vitetta
The effect of a monoclonal antibody coupled to ricin A chain-derived peptides on endothelial cells in vitro: insights into toxin-mediated vascular damage.
Experimental cell research 2000;258(2):417-24.
2000: B Clinchy; A Gazdar; Rosalia Rabinovsky; Eitan Yefenof; B Gordon; Ellen S Vitetta
The growth and metastasis of human, HER-2/neu-overexpressing tumor cell lines in male SCID mice.
Breast cancer research and treatment 2000;61(3):217-28.
2000: Ellen S Vitetta
Immunotoxins and vascular leak syndrome.
Cancer journal (Sudbury, Mass.) 2000;6 Suppl 3():S218-24.
2000: L Herrera; RA Farah; V A Pellegrini; DB Aquino; Eric S Sandler; George R Buchanan; Ellen S Vitetta
Immunotoxins against CD19 and CD22 are effective in killing precursor-B acute lymphoblastic leukemia cells in vitro.
Leukemia 2000;14(5):853-8.
2000: Richard A Messmann; Ellen S Vitetta; Donna Headlee; Adrian M Senderowicz; William D Figg; John Schindler; D F Michiel; Stephen Creekmore; Seth M Steinberg; David R Kohler; Elaine S Jaffe; Maryalice Stetler-Stevenson; H Chen; Victor Ghetie; Edward A Sausville
A phase I study of combination therapy with immunotoxins IgG-HD37-deglycosylated ricin A chain (dgA) and IgG-RFB4-dgA (Combotox) in patients with refractory CD19(+), CD22(+) B cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1302-13.
2000: B R Wei; Maria-Ana Ghetie; Ellen S Vitetta
The combined use of an immunotoxin and a radioimmunoconjugate to treat disseminated human B-cell lymphoma in immunodeficient mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):631-42.
2000: Victor Ghetie; Ellen S Vitetta
Chemical construction of immunotoxins.
Methods in molecular medicine 2000;25():1-26.
2000: Roland Schnell; Ellen S Vitetta; John Schindler; Peter Borchmann; Stefan Barth; Victor Ghetie; K Hell; S Drillich; Volker Diehl; Andreas Engert
Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin.
Leukemia 2000;14(1):129-35.
1999: Maria-Ana Ghetie; Victor Ghetie; Ellen S Vitetta
Anti-CD19 antibodies inhibit the function of the P-gp pump in multidrug-resistant B lymphoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(12):3920-7.
1999: Cynthia McCoig; G Van Dyke; C S Chou; Louis J Picker; Octavio Ramilo; Ellen S Vitetta
An anti-CD45RO immunotoxin eliminates T cells latently infected with HIV-1 in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11482-5.
1999: R Baluna; Josep Rizo; BE Gordon; Victor Ghetie; Ellen S Vitetta
Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3957-62.
1999: R Baluna; Ellen S Vitetta
An in vivo model to study immunotoxin-induced vascular leak in human tissue.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1999;22(1):41-7.
1998: B Clinchy; Ellen S Vitetta
The use of an anti-CD3 immunotoxin to prevent the development of lymphoproliferative disease in SCID/PBL mice.
Journal of immunological methods 1998;218(1-2):141-53.
1998: Roland Schnell; Ellen S Vitetta; John Schindler; Stefan Barth; U Winkler; Peter Borchmann; M L Hansmann; Volker Diehl; Victor Ghetie; Andreas Engert
Clinical trials with an anti-CD25 ricin A-chain experimental and immunotoxin (RFT5-SMPT-dgA) in Hodgkin's lymphoma.
Leukemia & lymphoma 1998;30(5-6):525-37.
1998: E E Gelber; Ellen S Vitetta
Effect of immunosuppressive agents on the immunogenicity and efficacy of an immunotoxin in mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(5):1297-304.
1998: RA Farah; B Clinchy; L Herrera; Ellen S Vitetta
The development of monoclonal antibodies for the therapy of cancer.
Critical reviews in eukaryotic gene expression 1998;8(3-4):321-56.
1998: Andreas Engert; Edward A Sausville; Ellen S Vitetta
The emerging role of ricin A-chain immunotoxins in leukemia and lymphoma.
Current topics in microbiology and immunology 1998;234():13-33.
1997: R Baluna; Ellen S Vitetta
Vascular leak syndrome: a side effect of immunotherapy.
Immunopharmacology 1997;37(2-3):117-32.
1997: Maria-Ana Ghetie; E M Podar; A Ilgen; BE Gordon; Jonathan Uhr; Ellen S Vitetta
Homodimerization of tumor-reactive monoclonal antibodies markedly increases their ability to induce growth arrest or apoptosis of tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7509-14.
1997: Maria-Ana Ghetie; Victor Ghetie; Ellen S Vitetta
Immunotoxins for the treatment of B-cell lymphomas.
Molecular medicine (Cambridge, Mass.) 1997;3(7):420-7.
1997: S Epzsteyn; Ellen S Vitetta; Eitan Yefenof
Prophylactic intervention in RadLV-induced lymphomagenesis with an anti-IL-4 monoclonal antibody.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1997;20(4):287-91.
1997: Ellen S Vitetta; Thomas F Tucker; E Racila; Y W Huang; Radu Marches; Nancy Lane; Richard Scheuermann; NE Street; T Watanabe; Jonathan Uhr
Tumor dormancy and cell signaling. V. Regrowth of the BCL1 tumor after dormancy is established.
Blood 1997;89(12):4425-36.
1997: Adrian M Senderowicz; Ellen S Vitetta; Donna Headlee; Victor Ghetie; Jonathan Uhr; William D Figg; Richard M Lush; Maryalice Stetler-Stevenson; G Kershaw; Douglas W Kingma; Elaine S Jaffe; Edward A Sausville
Complete sustained response of a refractory, post-transplantation, large B-cell lymphoma to an anti-CD22 immunotoxin.
Annals of internal medicine 1997;126(11):882-5.
1997: Jonathan Uhr; Richard Scheuermann; NE Street; Ellen S Vitetta
Cancer dormancy: opportunities for new therapeutic approaches.
Nature medicine 1997;3(5):505-9.
1997: Y W Huang; R Baluna; Ellen S Vitetta
Adhesion molecules as targets for cancer therapy.
Histology and histopathology 1997;12(2):467-77.
1997: C S Chou; Octavio Ramilo; Ellen S Vitetta
Highly purified CD25- resting T cells cannot be infected de novo with HIV-1.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1361-5.
1997: Andreas Engert; Volker Diehl; Roland Schnell; A Radszuhn; M T Hatwig; S Drillich; G Schön; Heribert Bohlen; Hans Tesch; M L Hansmann; Stefan Barth; John Schindler; Victor Ghetie; Jonathan Uhr; Ellen S Vitetta
A phase-I study of an anti-CD25 ricin A-chain immunotoxin (RFT5-SMPT-dgA) in patients with refractory Hodgkin's lymphoma.
Blood 1997;89(2):403-10.
1996: J M Armstrong; Ellen S Vitetta
The roles of Fas and perforin in LAK T-cell/bispecific antibody-mediated killing of the murine B-lymphoma cells, BCL1.
International journal of cancer. Journal international du cancer 1996;68(6):822-7.
1996: R Baluna; Edward A Sausville; M J Stone; M A Stetler-Stevenson; Jonathan Uhr; Ellen S Vitetta
Decreases in levels of serum fibronectin predict the severity of vascular leak syndrome in patients treated with ricin A chain-containing immunotoxins.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(10):1705-12.
1996: J Borvak; C S Chou; G Van Dyke; B Rosenwirth; Ellen S Vitetta; Octavio Ramilo
The use of cyclosporine, FK506, and SDZ NIM811 to prevent CD25- quiescent peripheral blood mononuclear cells from producing human immunodeficiency virus.
The Journal of infectious diseases 1996;174(4):850-3.
1996: Maria-Ana Ghetie; E M Podar; BE Gordon; P Pantazis; Jonathan Uhr; Ellen S Vitetta
Combination immunotoxin treatment and chemotherapy in SCID mice with advanced, disseminated Daudi lymphoma.
International journal of cancer. Journal international du cancer 1996;68(1):93-6.
1996: lee stone; Edward A Sausville; Joseph W Fay; Donna Headlee; Robert H Collins; William D Figg; Maryalice Stetler-Stevenson; V Jain; E S Jaffe; D Solomon; Richard M Lush; Adrian M Senderowicz; Victor Ghetie; J Schindler; J W Uhr; Ellen S Vitetta
A phase I study of bolus versus continuous infusion of the anti-CD19 immunotoxin, IgG-HD37-dgA, in patients with B-cell lymphoma.
Blood 1996;88(4):1188-97.
1996: R Baluna; Victor Ghetie; Nancy Oppenheimer-Marks; Ellen S Vitetta
Fibronectin inhibits the cytotoxic effect of ricin A chain on endothelial cells.
International journal of immunopharmacology 1996;18(6-7):355-61.
1996: Maria-Ana Ghetie; BE Gordon; E M Podar; Ellen S Vitetta
Effect of sublethal irradiation of SCID mice on growth of B-cell lymphoma xenografts and on efficacy of chemotherapy and/or immunotoxin therapy.
Laboratory animal science 1996;46(3):305-9.
1996: Octavio Ramilo; P J Hicks; J Borvak; L M Gross; D Zhong; JE Squires; Ellen S Vitetta
T cell activation and human immunodeficiency virus replication after influenza immunization of infected children.
The Pediatric infectious disease journal 1996;15(3):197-203.
1996: Jonathan Uhr; Radu Marches; E Racila; T F Tucker; R Hsueh; NE Street; Ellen S Vitetta; Richard Scheuermann
Role of antibody signaling in inducing tumor dormancy.
Advances in experimental medicine and biology 1996;406():69-74.
1996: G R Thrush; L R Lark; B C Clinchy; Ellen S Vitetta
Immunotoxins: an update.
Annual review of immunology 1996;14():49-71.
1995: F J Burrows; E J Derbyshire; P L Tazzari; P Amlot; Adi F Gazdar; S W King; M Letarte; Ellen S Vitetta; Philip E Thorpe
Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1623-34.
1995: Victor Ghetie; A Engert; R Schnell; Ellen S Vitetta
The in vivo anti-tumor activity of immunotoxins containing two versus one deglycosylated ricin A chains.
Cancer letters 1995;98(1):97-101.
1995: J Borvak; C S Chou; K Bell; G Van Dyke; H Zola; Octavio Ramilo; Ellen S Vitetta
Expression of CD25 defines peripheral blood mononuclear cells with productive versus latent HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(6):3196-204.
1995: Radu Marches; E Racila; T F Tucker; Louis J Picker; Patricia Mongini; R Hsueh; Ellen S Vitetta; Richard Scheuermann; Jonathan Uhr
Tumour dormancy and cell signalling--III: Role of hypercrosslinking of IgM and CD40 on the induction of cell cycle arrest and apoptosis in B lymphoma cells.
Therapeutic immunology 1995;2(3):125-36.
1995: E Racila; Richard Scheuermann; Louis J Picker; Eitan Yefenof; T Tucker; W Chang; Radu Marches; NE Street; Ellen S Vitetta; Jonathan Uhr
Tumor dormancy and cell signaling. II. Antibody as an agonist in inducing dormancy of a B cell lymphoma in SCID mice.
The Journal of experimental medicine 1995;181(4):1539-50.
1995: Y W Huang; Ellen S Vitetta
Immunotherapy of multiple myeloma.
Stem cells (Dayton, Ohio) 1995;13(2):123-34.
1995: Y W Huang; J A Richardson; Ellen S Vitetta
Anti-CD54 (ICAM-1) has antitumor activity in SCID mice with human myeloma cells.
Cancer research 1995;55(3):610-6.
1994: Ellen S Vitetta; Jonathan Uhr
Monoclonal antibodies as agonists: an expanded role for their use in cancer therapy.
Cancer research 1994;54(20):5301-9.
1994: Maria-Ana Ghetie; Ellen S Vitetta
Recent developments in immunotoxin therapy.
Current opinion in immunology 1994;6(5):707-14.
1994: Victor Ghetie; Ellen S Vitetta
Immunotoxins in the therapy of cancer: from bench to clinic.
Pharmacology & therapeutics 1994;63(3):209-34.
1994: Ellen S Vitetta
From the basic science of B cells to biological missiles at the bedside.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(4):1407-20.
1994: Maria-Ana Ghetie; K Tucker; J Richardson; Jonathan Uhr; Ellen S Vitetta
Eradication of minimal disease in severe combined immunodeficient mice with disseminated Daudi lymphoma using chemotherapy and an immunotoxin cocktail.
Blood 1994;84(3):702-7.
1994: Richard Scheuermann; E Racila; T Tucker; Eitan Yefenof; NE Street; Ellen S Vitetta; Louis J Picker; Jonathan Uhr
Lyn tyrosine kinase signals cell cycle arrest but not apoptosis in B-lineage lymphoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):4048-52.
1994: G L Shen; J L Li; Ellen S Vitetta
Bispecific anti-CD22/anti-CD3-ricin A chain immunotoxin is cytotoxic to Daudi lymphoma cells but not T cells in vitro and shows both A-chain-mediated and LAK-T-mediated killing.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2368-76.
1994: Maria-Ana Ghetie; Louis J Picker; J A Richardson; K Tucker; Jonathan Uhr; Ellen S Vitetta
Anti-CD19 inhibits the growth of human B-cell tumor lines in vitro and of Daudi cells in SCID mice by inducing cell cycle arrest.
Blood 1994;83(5):1329-36.
1993: Y W Huang; F J Burrows; Ellen S Vitetta
Cytotoxicity of a novel anti-ICAM-1 immunotoxin on human myeloma cell lines.
Hybridoma 1993;12(6):661-75.
1993: Victor Ghetie; E Swindell; Jonathan Uhr; Ellen S Vitetta
Purification and properties of immunotoxins containing one vs. two deglycosylated ricin A chains.
Journal of immunological methods 1993;166(1):117-22.
1993: Y W Huang; Ellen S Vitetta
A monoclonal anti-human IL-6 receptor antibody inhibits the proliferation of human myeloma cells.
Hybridoma 1993;12(5):621-30.
1993: Eitan Yefenof; Louis J Picker; Richard Scheuermann; Ellen S Vitetta; NE Street; T F Tucker; Jonathan Uhr
Induction of B cell tumor dormancy by anti-idiotypic antibodies.
Current opinion in immunology 1993;5(5):740-4.
1993: Octavio Ramilo; K D Bell; Jonathan Uhr; Ellen S Vitetta
Role of CD25+ and CD25-T cells in acute HIV infection in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(11):5202-8.
1993: Ellen S Vitetta; Philip E Thorpe; Jonathan Uhr
Immunotoxins: magic bullets or misguided missiles?
Immunology today 1993;14(6):252-9.
1993: A M Soler-Rodríguez; Maria-Ana Ghetie; Nancy Oppenheimer-Marks; Jonathan Uhr; Ellen S Vitetta
Ricin A-chain and ricin A-chain immunotoxins rapidly damage human endothelial cells: implications for vascular leak syndrome.
Experimental cell research 1993;206(2):227-34.
1993: A W Tong; Y W Huang; B Q Zhang; GEORGES NETTO; Ellen S Vitetta; M J Stone
Heterotransplantation of human multiple myeloma cell lines in severe combined immunodeficiency (SCID) mice.
Anticancer research 1993;13(3):593-7.
1993: Ellen S Vitetta; Philip E Thorpe; Jonathan Uhr
Immunotoxins: magic bullets or misguided missiles?
Trends in pharmacological sciences 1993;14(5):148-54.
1993: Y W Huang; J A Richardson; A W Tong; B Q Zhang; M J Stone; Ellen S Vitetta
Disseminated growth of a human multiple myeloma cell line in mice with severe combined immunodeficiency disease.
Cancer research 1993;53(6):1392-6.
1993: Eitan Yefenof; Louis J Picker; Richard Scheuermann; T F Tucker; Ellen S Vitetta; Jonathan Uhr
Cancer dormancy: isolation and characterization of dormant lymphoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1829-33.
1993: K D Bell; Octavio Ramilo; Ellen S Vitetta
Combined use of an immunotoxin and cyclosporine to prevent both activated and quiescent peripheral blood T cells from producing type 1 human immunodeficiency virus.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1411-5.
1992: Victor Ghetie; T Wheeler; D Scott; Jonathan Uhr; Ellen S Vitetta
A CD4-derived peptide carrier blocks acute HIV-1 infection in vitro and binds to gp120 in the presence of Walter-Reed stage 1-6 HIV+ sera.
AIDS research and human retroviruses 1992;8(11):1945-8.
1992: Maria-Ana Ghetie; K Tucker; J Richardson; Jonathan Uhr; Ellen S Vitetta
The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin.
Blood 1992;80(9):2315-20.
1992: W T Lee; Ellen S Vitetta
Memory T cells are anergic to the superantigen staphylococcal enterotoxin B.
The Journal of experimental medicine 1992;176(2):575-9.
1992: X M Yin; Ellen S Vitetta
The lineage relationship between virgin and memory B cells.
International immunology 1992;4(6):691-8.
1992: W T Lee; Ellen S Vitetta
Changes in expression of CD45R during the development of Th1 and Th2 cell lines.
European journal of immunology 1992;22(6):1455-9.
1992: Michael Berton; Ellen S Vitetta
IL-4-induced expression of germline gamma 1 transcripts in B cells following cognate interactions with T helper cells.
International immunology 1992;4(3):387-96.
1992: Eitan Yefenof; C Ela; Moshe Kotler; Ellen S Vitetta
Induction of IL-4 secretion by the radiation leukemia virus (RadLV): role in autocrine growth stimulation of RadLV infected pre-leukemic cells.
International journal of cancer. Journal international du cancer 1992;50(3):481-5.
1992: A M Soler-Rodriguez; Jonathan Uhr; J Richardson; Ellen S Vitetta
The toxicity of chemically deglycosylated ricin A-chain in mice.
International journal of immunopharmacology 1992;14(2):281-91.
1992: Eitan Yefenof; G Abboud; S Epszteyn; Ellen S Vitetta
Treatment of premalignancy: prevention of lymphoma in radiation leukemia virus-inoculated mice by cyclosporin A and immunotoxin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):728-32.
1991: Maria-Ana Ghetie; J Richardson; T Tucker; D Jones; Jonathan Uhr; Ellen S Vitetta
Antitumor activity of Fab' and IgG-anti-CD22 immunotoxins in disseminated human B lymphoma grown in mice with severe combined immunodeficiency disease: effect on tumor cells in extranodal sites.
Cancer research 1991;51(21):5876-80.
1991: C Burger; Ellen S Vitetta
The response of B cells in spleen, Peyer's patches, and lymph nodes to LPS and IL-4.
Cellular immunology 1991;138(1):35-43.
1991: X M Yin; W T Lee; Ellen S Vitetta
Changes in expression of J11d on murine B cells during activation and generation of memory.
Cellular immunology 1991;137(2):448-60.
1991: X M Yin; Ellen S Vitetta
IL-4 down-regulates the expression of J11d on murine B cells.
Cellular immunology 1991;137(2):461-73.
1991: Jonathan Uhr; T Tucker; R D May; H Siu; Ellen S Vitetta
Cancer dormancy: studies of the murine BCL1 lymphoma.
Cancer research 1991;51(18 Suppl):5045s-5053s.
1991: Victor Ghetie; P Thorpe; Maria-Ana Ghetie; P Knowles; Jonathan Uhr; Ellen S Vitetta
The GLP large scale preparation of immunotoxins containing deglycosylated ricin A chain and a hindered disulfide bond.
Journal of immunological methods 1991;142(2):223-30.
1991: R Fernandez-Botran; Ellen S Vitetta
Evidence that natural murine soluble interleukin 4 receptors may act as transport proteins.
The Journal of experimental medicine 1991;174(3):673-81.
1991: W T Lee; Ellen S Vitetta
Virgin T cells do not provide help for antigen-specific B cells in the absence of IL-4, IL-5, and IL-6.
International immunology 1991;3(9):907-16.
1991: Ellen S Vitetta; M Stone; P Amlot; J Fay; R May; M Till; J Newman; P Clark; R Collins; D Cunningham
Phase I immunotoxin trial in patients with B-cell lymphoma.
Cancer research 1991;51(15):4052-8.
1991: Victor Ghetie; C Slaughter; H T Wheeler; Jonathan Uhr; Ellen S Vitetta
CD4 peptide-protein conjugates, but not recombinant human CD4, bind to recombinant gp120 from the human immunodeficiency virus in the presence of serum from AIDS patients.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5690-3.
1991: R D May; H T Wheeler; F D Finkelman; Jonathan Uhr; Ellen S Vitetta
Intracellular routing rather than cross-linking or rate of internalization determines the potency of immunotoxins directed against different epitopes of sIgD on murine B cells.
Cellular immunology 1991;135(2):490-500.
1991: A Bossie; Ellen S Vitetta
IFN-gamma enhances secretion of IgG2a from IgG2a-committed LPS-stimulated murine B cells: implications for the role of IFN-gamma in class switching.
Cellular immunology 1991;135(1):95-104.
1991: Maria-Ana Ghetie; Jonathan Uhr; Ellen S Vitetta
Covalent binding of human alpha 2-macroglobulin to deglycosylated ricin A chain and its immunotoxins.
Cancer research 1991;51(5):1482-7.
1991: Ellen S Vitetta; Philip E Thorpe
Immunotoxins containing ricin or its A chain.
Seminars in cell biology 1991;2(1):47-58.
1991: Ellen S Vitetta; Michael Berton; C Burger; M Kepron; W T Lee; X M Yin
Memory B and T cells.
Annual review of immunology 1991;9():193-217.
1991: Virginia M Sanders; Ellen S Vitetta
B cell-associated LFA-1 and T cell-associated ICAM-1 transiently cluster in the area of contact between interacting cells.
Cellular immunology 1991;132(1):45-55.
1991: W T Lee; Ellen S Vitetta
The differential expression of homing and adhesion molecules on virgin and memory T cells in the mouse.
Cellular immunology 1991;132(1):215-22.
1990: Ellen S Vitetta
Immunotoxins: new therapeutic reagents for autoimmunity, cancer, and AIDS.
Journal of clinical immunology 1990;10(6 Suppl):15S-18S.
1990: W T Lee; Ellen S Vitetta
Limiting dilution analysis of CD45Rhi and CD45Rlo T cells: further evidence that CD45Rlo cells are memory cells.
Cellular immunology 1990;130(2):459-71.
1990: Michael Berton; Ellen S Vitetta
Interleukin 4 induces changes in the chromatin structure of the gamma 1 switch region in resting B cells before switch recombination.
The Journal of experimental medicine 1990;172(1):375-8.
1990: Ellen S Vitetta; N Yen
Expression and functional properties of genetically engineered ricin B chain lacking galactose-binding activity.
Biochimica et biophysica acta 1990;1049(2):151-7.
1990: R Fernandez-Botran; Ellen S Vitetta
A soluble, high-affinity, interleukin-4-binding protein is present in the biological fluids of mice.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4202-6.
1990: W T Lee; X M Yin; Ellen S Vitetta
Functional and ontogenetic analysis of murine CD45Rhi and CD45Rlo CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3288-95.
1990: R D May; F D Finkelman; H T Wheeler; Jonathan Uhr; Ellen S Vitetta
Evaluation of ricin A chain-containing immunotoxins directed against different epitopes on the delta-chain of cell surface-associated IgD on murine B cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3637-42.
1990: Maria-Ana Ghetie; J Richardson; T Tucker; D Jones; Jonathan Uhr; Ellen S Vitetta
Disseminated or localized growth of a human B-cell tumor (Daudi) in SCID mice.
International journal of cancer. Journal international du cancer 1990;45(3):481-5.
1990: T L Stevens; Ellen S Vitetta
Antigen-specific sIalo B cells do not secrete IgG2a in response to TH1 cells and antigen: responsiveness can be restored by IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(3):869-74.
1990: Victor Ghetie; M A Till; Maria-Ana Ghetie; Jonathan Uhr; Ellen S Vitetta
Large scale preparation of an immunoconjugate constructed with human recombinant CD4 and deglycosylated ricin A chain.
Journal of immunological methods 1990;126(1):135-41.
1990: M A Till; Victor Ghetie; R D May; P C Auerbach; Susan Zolla-Pazner; M K Gorny; T Gregory; Jonathan Uhr; Ellen S Vitetta
Immunoconjugates containing ricin A chain and either human anti-gp41 or CD4 kill H9 cells infected with different isolates of HIV, but do not inhibit normal T or B cell function.
Journal of acquired immune deficiency syndromes 1990;3(6):609-14.
1990: Victor Ghetie; M A Till; Maria-Ana Ghetie; T Tucker; J Porter; E J Patzer; J A Richardson; Jonathan Uhr; Ellen S Vitetta
Preparation and characterization of conjugates of recombinant CD4 and deglycosylated ricin A chain using different cross-linkers.
Bioconjugate chemistry 1990;1(1):24-31.
1989: M R Kepron; Y W Chen; Jonathan Uhr; Ellen S Vitetta
IL-4 induces the specific rearrangement of gamma 1 genes on the expressed and unexpressed chromosomes of lipopolysaccharide-activated normal murine B cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(1):334-9.
1989: R Fernandez-Botran; Jonathan Uhr; Ellen S Vitetta
Cross-linking of interleukin 4 to surface molecules on murine T and B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4235-9.
1989: C D Myers; Ellen S Vitetta
Splenic B cells and antigen-specific B cells process anti-Ig in a similar manner.
Cellular immunology 1989;121(1):174-84.
1989: NE Street; K Uyemura; Virginia M Sanders; Jonathan Uhr; Ellen S Vitetta
In vivo administration of Fab' fragments of anti-L3T4 (GK1.5) antibody inhibits the T helper cell function of murine lymph node cells.
Cellular immunology 1989;120(1):75-81.
1989: Michael Berton; Jonathan Uhr; Ellen S Vitetta
Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2829-33.
1989: M A Till; Susan Zolla-Pazner; M K Gorny; J S Patton; Jonathan Uhr; Ellen S Vitetta
Human immunodeficiency virus-infected T cells and monocytes are killed by monoclonal human anti-gp41 antibodies coupled to ricin A chain.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(6):1987-91.
1989: R Fernandez-Botran; Virginia M Sanders; Ellen S Vitetta
Interactions between receptors for interleukin 2 and interleukin 4 on lines of helper T cells (HT-2) and B lymphoma cells (BCL1).
The Journal of experimental medicine 1989;169(2):379-91.
1989: Jonathan Uhr; R J Fulton; M A Till; R D May; Ellen S Vitetta
Monoclonal antibodies as carriers of toxins.
Progress in clinical and biological research 1989;288():403-12.
1989: Ellen S Vitetta; R Fernandez-Botran; C D Myers; Virginia M Sanders
Cellular interactions in the humoral immune response.
Advances in immunology 1989;45():1-105.
1989: R Fernandez-Botran; Virginia M Sanders; Ellen S Vitetta
Regulation of the biological effects of IL-4 on murine T and B cells.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():705-11.
1989: C D Myers; Ellen S Vitetta
The processing of antigen and anti-Ig by antigen-specific B cells.
The Journal of molecular and cellular immunology : JMCI 1989;4(4):179-87; discussion 187-90.
1988: M A Till; Victor Ghetie; T Gregory; E J Patzer; J P Porter; Jonathan Uhr; D J Capon; Ellen S Vitetta
HIV-infected cells are killed by rCD4-ricin A chain.
Science (New York, N.Y.) 1988;242(4882):1166-8.
1988: Virginia M Sanders; R Fernandez-Botran; R L Coffman; T R Mosmann; Ellen S Vitetta
A single antigen-specific B cell can conjugate to either a type 1 or a type 2 helper T cell.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7724-8.
1988: Victor Ghetie; Maria-Ana Ghetie; Jonathan Uhr; Ellen S Vitetta
Large scale preparation of immunotoxins constructed with the Fab' fragment of IgG1 murine monoclonal antibodies and chemically deglycosylated ricin A chain.
Journal of immunological methods 1988;112(2):267-77.
1988: R Fernandez-Botran; Virginia M Sanders; T R Mosmann; Ellen S Vitetta
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells.
The Journal of experimental medicine 1988;168(2):543-58.
1988: T L Stevens; A Bossie; Virginia M Sanders; R Fernandez-Botran; R L Coffman; T R Mosmann; Ellen S Vitetta
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells.
Nature 1988;334(6179):255-8.
1988: R J Fulton; Jonathan Uhr; Ellen S Vitetta
In vivo therapy of the BCL1 tumor: effect of immunotoxin valency and deglycosylation of the ricin A chain.
Cancer research 1988;48(9):2626-31.
1988: R J Fulton; T F Tucker; Ellen S Vitetta; Jonathan Uhr
Pharmacokinetics of tumor-reactive immunotoxins in tumor-bearing mice: effect of antibody valency and deglycosylation of the ricin A chain on clearance and tumor localization.
Cancer research 1988;48(9):2618-25.
1988: M Till; R D May; Jonathan Uhr; P E Thorpe; Ellen S Vitetta
An assay that predicts the ability of monoclonal antibodies to form potent ricin A chain-containing immunotoxins.
Cancer research 1988;48(5):1119-23.
1988: Ellen S Vitetta
The development of immunotoxins for the therapy of cancer, AIDS, and immune dysfunctions.
Princess Takamatsu symposia 1988;19():333-40.
1988: M L Birkeland; J Metlay; Virginia M Sanders; R Fernandez-Botran; Ellen S Vitetta; Ralph M Steinman; Ellen Puré
Epitopes on CD45R [T200] molecules define differentiation antigens on murine B and T lymphocytes.
The Journal of molecular and cellular immunology : JMCI 1988;4(2):71-85.
1987: Ellen S Vitetta; R J Fulton; R D May; M Till; Jonathan Uhr
Redesigning nature's poisons to create anti-tumor reagents.
Science (New York, N.Y.) 1987;238(4830):1098-104.
1987: Virginia M Sanders; R Fernandez-Botran; Jonathan Uhr; Ellen S Vitetta
Interleukin 4 enhances the ability of antigen-specific B cells to form conjugates with T cells.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(7):2349-54.
1987: Ellen S Vitetta; A Bossie; R Fernandez-Botran; C D Myers; K G Oliver; Virginia M Sanders; T L Stevens
Interaction and activation of antigen-specific T and B cells.
Immunological reviews 1987;99():193-239.
1987: NE Street; R J Fulton; Virginia M Sanders; Ellen S Vitetta
Inhibition of the helper function of murine T cells with Fab'-anti-L3T4 ricin A chain immunotoxin.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(5):1734-8.
1987: A Bossie; K H Brooks; P H Krammer; Ellen S Vitetta
Activation of murine B cells from different tissues with different mitogens. II. Isotype distribution of secreted immunoglobulins in the presence and absence of IL-4-containing T cell supernatants.
The Journal of molecular and cellular immunology : JMCI 1987;3(4):221-6.
1987: K H Brooks; Ellen S Vitetta
Activation of murine B cells with Salmonella typhimurium mitogen (STM), lipopolysaccharide (LPS), and dextran sulfate (DxS). I. Cell-cycle analysis and induction of cytoplasmic immunoglobulin.
The Journal of molecular and cellular immunology : JMCI 1987;3(4):215-9.
1986: R Fernandez-Botran; Virginia M Sanders; K G Oliver; Y W Chen; P H Krammer; Jonathan Uhr; Ellen S Vitetta
Interleukin 4 mediates autocrine growth of helper T cells after antigenic stimulation.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(24):9689-93.
1986: C D Myers; Virginia M Sanders; Ellen S Vitetta
Isolation of antigen-binding virgin and memory B cells.
Journal of immunological methods 1986;92(1):45-57.
1986: H Siu; Ellen S Vitetta; R D May; Jonathan Uhr
Tumor dormancy. I. Regression of BCL1 tumor and induction of a dormant tumor state in mice chimeric at the major histocompatibility complex.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(4):1376-82.
1986: R J Fulton; D C Blakey; P P Knowles; Jonathan Uhr; Philip E Thorpe; Ellen S Vitetta
Purification of ricin A1, A2, and B chains and characterization of their toxicity.
The Journal of biological chemistry 1986;261(12):5314-9.
1985: S Jones; J Layton; P H Krammer; Ellen S Vitetta; Philip W Tucker
The effect of T cell-derived lymphokines on the levels of isotype-specific RNA in normal B cells.
The Journal of molecular and cellular immunology : JMCI 1985;2(3):143-53.
1985: J E Layton; P H Krammer; T Hamaoka; Jonathan Uhr; Ellen S Vitetta
Small and large B cells respond differently to T cell-derived B cell growth and differentiation factors.
The Journal of molecular and cellular immunology : JMCI 1985;2(3):155-67.