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Elly Vitters

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Anatomy

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Chemicals & Drugs

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Injections, Intra-Articular

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D F G Remst; J M Snabel; R Stoop; Wim B van den Berg; R A Bank; Esmeralda N Blaney Davidson; Arjen B Blom; Elly L Vitters; Peter van der Kraan
Osteoarthritis-related fibrosis is associated with both elevated pyridinoline cross-link formation and lysyl hydroxylase 2b expression.
Catharine A Hellingman; Esmeralda N Blaney Davidson; Wendy J L M Koevoet; Elly L Vitters; Wim B van den Berg; Gerjo J V M van Osch; Peter M van der Kraan
Smad signaling determines chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells: inhibition of Smad1/5/8P prevents terminal differentiation and calcification.
Esmeralda N Blaney Davidson; Dennis F G Remst; Elly L Vitters; Henk M van Beuningen; Arjen B Blom; Marie-Jose Goumans; Wim B van den Berg; Peter van der Kraan
Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.

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All Publications

2013: D F G Remst; J M Snabel; R Stoop; Wim B van den Berg; R A Bank; Esmeralda N Blaney Davidson; Arjen B Blom; Elly L Vitters; Peter van der Kraan
Osteoarthritis-related fibrosis is associated with both elevated pyridinoline cross-link formation and lysyl hydroxylase 2b expression.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2013;21(1):157-64.
2011: Catharine A Hellingman; Esmeralda N Blaney Davidson; Wendy J L M Koevoet; Elly L Vitters; Wim B van den Berg; Gerjo J V M van Osch; Peter M van der Kraan
Smad signaling determines chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells: inhibition of Smad1/5/8P prevents terminal differentiation and calcification.
Tissue engineering. Part A 2011;17(7-8):1157-67.
2009: Esmeralda N Blaney Davidson; Dennis F G Remst; Elly L Vitters; Henk M van Beuningen; Arjen B Blom; Marie-Jose Goumans; Wim B van den Berg; Peter van der Kraan
Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7937-45.
2007: E N Blaney Davidson; Elly L Vitters; Henk M van Beuningen; Fons A J van de Loo; Wim B van den Berg; Peter van der Kraan
Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation.
Arthritis and rheumatism 2007;56(12):4065-73.
2007: Esmeralda N Blaney Davidson; Elly L Vitters; P L E M van Lent; Fons A J van de Loo; Wim B van den Berg; Peter van der Kraan
Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling.
Arthritis research & therapy 2007;9(5):R102.
2006: Esmeralda N Blaney Davidson; Elly L Vitters; Peter van der Kraan; Wim B van den Berg
Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation.
Annals of the rheumatic diseases 2006;65(11):1414-21.
2006: Esmeralda N Blaney Davidson; Elly L Vitters; F M Mooren; N Oliver; W B van den Berg; Peter van der Kraan
Connective tissue growth factor/CCN2 overexpression in mouse synovial lining results in transient fibrosis and cartilage damage.
Arthritis and rheumatism 2006;54(5):1653-61.
2006: Esmeralda N Blaney Davidson; Elly L Vitters; Wim B van den Berg; Peter van der Kraan
TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7.
Arthritis research & therapy 2006;8(3):R65.
2005: N Takahashi; K Rieneck; Peter van der Kraan; Henk M van Beuningen; Elly L Vitters; Klaus Bendtzen; Wim B van den Berg
Elucidation of IL-1/TGF-beta interactions in mouse chondrocyte cell line by genome-wide gene expression.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2005;13(5):426-38.
2005: Esmeralda N Blaney Davidson; Alwin Scharstuhl; Elly L Vitters; Peter van der Kraan; Wim B van den Berg
Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity.
Arthritis research & therapy 2005;7(6):R1338-47.
2004: P L E M van Lent; Arjen B Blom; Peter van der Kraan; A E M Holthuysen; Elly L Vitters; Nico van Rooijen; Ruben L Smeets; K C A M Nabbe; Wim B van den Berg
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation.
Arthritis and rheumatism 2004;50(1):103-11.
2003: Alwin Scharstuhl; Elly L Vitters; Peter van der Kraan; Wim B van den Berg
Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis.
Arthritis and rheumatism 2003;48(12):3442-51.
2003: Alwin Scharstuhl; Robin J W Diepens; Joost Lensen; Elly L Vitters; Henk M van Beuningen; Peter van der Kraan; Wim B van den Berg
Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-beta-mediated chondrocyte proliferation and proteoglycan synthesis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2003;11(11):773-82.
2003: Alwin Scharstuhl; Harrie L Glansbeek; Elly L Vitters; Peter van der Kraan; Wim B van den Berg
Large scale protein production of the extracellular domain of the transforming growth factor-beta type II receptor using the Pichia pastoris expression system.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;786(1-2):271-7.
2002: Alwin Scharstuhl; Henk M van Beuningen; Elly L Vitters; Peter van der Kraan; Wim B van den Berg
Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice.
Annals of the rheumatic diseases 2002;61(12):1095-8.
2002: Alwin Scharstuhl; Harrie L Glansbeek; Henk M van Beuningen; Elly L Vitters; Peter van der Kraan; Wim B van den Berg
Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):507-14.
2000: Peter van der Kraan; Elly L Vitters; Henk M van Beuningen; Fons A J van de Loo; Wim B van den Berg
Role of nitric oxide in the inhibition of BMP-2-mediated stimulation of proteoglycan synthesis in articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2000;8(2):82-6.
1998: Peter van der Kraan; Elly L Vitters; Tineke Meijers; A Robin Poole; Wim B van den Berg
Collagen type I antisense and collagen type IIA messenger RNA is expressed in adult murine articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1998;6(6):417-26.
1998: Harrie L Glansbeek; Henk M van Beuningen; Elly L Vitters; Peter van der Kraan; Wim B van den Berg
Expression of recombinant human soluble type II transforming growth factor-beta receptor in Pichia pastoris and Escherichia coli: two powerful systems to express a potent inhibitor of transforming growth factor-beta.
Protein expression and purification 1998;12(2):201-7.
1998: Harrie L Glansbeek; Henk M van Beuningen; Elly L Vitters; Peter van der Kraan; Wim B van den Berg
Stimulation of articular cartilage repair in established arthritis by local administration of transforming growth factor-beta into murine knee joints.
Laboratory investigation; a journal of technical methods and pathology 1998;78(2):133-42.
1997: Harrie L Glansbeek; Henk M van Beuningen; Elly L Vitters; E A Morris; Peter van der Kraan; Wim B van den Berg
Bone morphogenetic protein 2 stimulates articular cartilage proteoglycan synthesis in vivo but does not counteract interleukin-1alpha effects on proteoglycan synthesis and content.
Arthritis and rheumatism 1997;40(6):1020-8.
1997: Harrie L Glansbeek; Peter van der Kraan; F P Lafeber; Elly L Vitters; Wim B van den Berg
Species-specific expression of type II TGF-beta receptor isoforms by articular chondrocytes: effect of proteoglycan depletion and aging.
Cytokine 1997;9(5):347-51.
1997: Peter van der Kraan; Harrie L Glansbeek; Elly L Vitters; Wim B van den Berg
Early elevation of transforming growth factor-beta, decorin, and biglycan mRNA levels during cartilage matrix restoration after mild proteoglycan depletion.
The Journal of rheumatology 1997;24(3):543-9.
1994: Peter van der Kraan; J de Lange; Elly L Vitters; Henk M van Beuningen; Gerjo J V M van Osch; P L E M van Lent; Wim B van den Berg
Analysis of changes in proteoglycan content in murine articular cartilage using image analysis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1994;2(3):207-14.
1994: P J Verschure; Peter van der Kraan; Elly L Vitters; Wim B van den Berg
Stimulation of proteoglycan synthesis by triamcinolone acetonide and insulin-like growth factor 1 in normal and arthritic murine articular cartilage.
The Journal of rheumatology 1994;21(5):920-6.
1993: Harrie L Glansbeek; Peter van der Kraan; Elly L Vitters; Wim B van den Berg
Correlation of the size of type II transforming growth factor beta (TGF-beta) receptor with TGF-beta responses of isolated bovine articular chondrocytes.
Annals of the rheumatic diseases 1993;52(11):812-6.
1993: Peter van der Kraan; Elly L Vitters; N S Postma; J Verbunt; Wim B van den Berg
Maintenance of the synthesis of large proteoglycans in anatomically intact murine articular cartilage by steroids and insulin-like growth factor I.
Annals of the rheumatic diseases 1993;52(10):734-41.
1993: Gerjo J V M van Osch; Peter van der Kraan; Elly L Vitters; Leendert Blankevoort; Wim B van den Berg
Induction of osteoarthritis by intra-articular injection of collagenase in mice. Strain and sex related differences.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1993;1(3):171-7.
1993: Harrie L Glansbeek; Peter van der Kraan; Elly L Vitters; Wim B van den Berg
Variable TGF-beta receptor expression regulates TGF-beta responses of articular chondrocytes.
Agents and actions. Supplements 1993;39():139-45.
1992: Floris P J G Lafeber; Peter van der Kraan; H L van Roy; Elly L Vitters; O Huber-Bruning; Wim B van den Berg; J W J Bijlsma
Local changes in proteoglycan synthesis during culture are different for normal and osteoarthritic cartilage.
The American journal of pathology 1992;140(6):1421-9.
1992: Peter van der Kraan; Elly L Vitters; Henk M van Beuningen; Wim B van den Berg
Proteoglycan synthesis and osteophyte formation in 'metabolically' and 'mechanically' induced murine degenerative joint disease: an in-vivo autoradiographic study.
International journal of experimental pathology 1992;73(3):335-50.
1992: Peter van der Kraan; Elly L Vitters; Wim B van den Berg
Inhibition of proteoglycan synthesis by transforming growth factor beta in anatomically intact articular cartilage of murine patellae.
Annals of the rheumatic diseases 1992;51(5):643-7.
1992: Peter van der Kraan; Elly L Vitters; Wim B van den Berg
Differential effect of transforming growth factor beta on freshly isolated and cultured articular chondrocytes.
The Journal of rheumatology 1992;19(1):140-5.
1990: Peter van der Kraan; Elly L Vitters; B J de Vries; Wim B van den Berg
High susceptibility of human articular cartilage glycosaminoglycan synthesis to changes in inorganic sulfate availability.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1990;8(4):565-71.
1990: Peter van der Kraan; Elly L Vitters; B J de Vries; Wim B van den Berg; L B A Van De Putte
The effect of chronic paracetamol administration to rats on the glycosaminoglycan content of patellar cartilage.
Agents and actions 1990;29(3-4):218-23.
1990: Peter van der Kraan; Elly L Vitters; Henk M van Beuningen; L B A Van De Putte; Wim B van den Berg
Degenerative knee joint lesions in mice after a single intra-articular collagenase injection. A new model of osteoarthritis.
Journal of experimental pathology (Oxford, England) 1990;71(1):19-31.
1989: Peter van der Kraan; Elly L Vitters; L B A Van De Putte; Wim B van den Berg
Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints.
The American journal of pathology 1989;135(6):1001-14.
1989: Peter van der Kraan; B J de Vries; Elly L Vitters; Wim B van den Berg; L B A Van De Putte
The effect of low sulfate concentrations on the glycosaminoglycan synthesis in anatomically intact articular cartilage of the mouse.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1989;7(5):645-53.
1988: Peter van der Kraan; B J de Vries; Elly L Vitters; Wim B van den Berg; L B A Van De Putte
Inhibition of glycosaminoglycan synthesis in anatomically intact rat patellar cartilage by paracetamol-induced serum sulfate depletion.
Biochemical pharmacology 1988;37(19):3683-90.
1988: Peter van der Kraan; Elly L Vitters; B J de Vries; Wim B van den Berg; L B A Van De Putte
Synthesis of aberrant glycosaminoglycans during cartilage culture in 'sulfate free' medium.
Journal of biochemical and biophysical methods 1988;15(5):273-7.
1988: Peter van der Kraan; B J de Vries; Wim B van den Berg; Elly L Vitters; L B A Van De Putte
Effects of drug-mediated serum sulfate depletion on glycosaminoglycan synthesis.
Agents and actions 1988;23(1-2):55-7.
1988: B J de Vries; Wim B van den Berg; Elly L Vitters; L B A Van De Putte
The influence of antirheumatic drugs on basal and accelerated breakdown of articular proteoglycans.
Agents and actions 1988;23(1-2):52-4.
1988: B J de Vries; W B van den Berg; Elly L Vitters; L B A Van De Putte
Effects of NSAIDs on the metabolism of sulphated glycosaminoglycans in healthy and (post) arthritic murine articular cartilage.
Drugs 1988;35 Suppl 1():24-32.
1988: B J de Vries; Wim B van den Berg; Elly L Vitters; L B A Van De Putte
Effect of nonsteroidal antiinflammatory drugs on cartilage destruction in antigen induced arthritis in mice.
Scandinavian journal of rheumatology. Supplement 1988;77():23-8.
1987: B J de Vries; Elly L Vitters; Wim B van den Berg; D Schram; L B A Van De Putte
Determination of small quantities of sulfate (0-12 nmol) in serum, urine, and cartilage of the mouse.
Analytical biochemistry 1987;163(2):408-17.
1986: B J de Vries; W B van den Berg; Elly L Vitters; L B van de Putte
The effect of salicylate on anatomically intact articular cartilage is influenced by sulfate and serum in the culture medium.
The Journal of rheumatology 1986;13(4):686-93.
1986: B J de Vries; W B van den Berg; Elly L Vitters; L B van de Putte
Quantitation of glycosaminoglycan metabolism in anatomically intact articular cartilage of the mouse patella: in vitro and in vivo studies with 35S-sulfate, 3H-glucosamine, and 3H-acetate.
Rheumatology international 1986;6(6):273-81.