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Michael Boyle

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Publications

TOP 3
Nicholas J Boylan; Michael P Boyle; Mark J Cooper; Raz Jelinek; Samuel Lai; Jung Soo Suk; Justin Hanes
Highly compacted DNA nanoparticles with low MW PEG coatings: in vitro, ex vivo and in vivo evaluation.
J P Clancy; Martyn Botfield; Laurent Vernillet; Kris De Boeck; Moira L Aitken; Anissa Leonard; Jordan M Dunitz; Michael P Boyle; Michael S Schechter; Joseph M Pilewski; George T Spencer-Green; Karl Yen; Henry L Dorkin; Preston W Campbell; Manfred Ballmann; Richard B Moss; Claudia L Ordoñez; Ronald C Rubenstein; Manu Jain; Steve Wisseh; Steven M Rowe; Raouf S Amin; Scott H Donaldson; Peter R Durie; Karen S McCoy; Daniel B Rosenbluth; Inez Bronsveld; Frank J Accurso; Melissa A Ashlock; Michael W Konstan
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.
Jung Soo Suk; Benjamin Tang; Kanika Trehan; Pamela L Zeitlin; Nicholas J Boylan; Michael P Boyle; Mark J Cooper; Samuel Lai; Jung-Ming G Lin; Craig S Schneider; Justin Hanes
N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.

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All Publications

2012: Nicholas J Boylan; Michael P Boyle; Mark J Cooper; Raz Jelinek; Samuel Lai; Jung Soo Suk; Justin Hanes
Highly compacted DNA nanoparticles with low MW PEG coatings: in vitro, ex vivo and in vivo evaluation.
Journal of controlled release : official journal of the Controlled Release Society 2012;157(1):72-9.
2012: J P Clancy; Martyn Botfield; Laurent Vernillet; Kris De Boeck; Moira L Aitken; Anissa Leonard; Jordan M Dunitz; Michael P Boyle; Michael S Schechter; Joseph M Pilewski; George T Spencer-Green; Karl Yen; Henry L Dorkin; Preston W Campbell; Manfred Ballmann; Richard B Moss; Claudia L Ordoñez; Ronald C Rubenstein; Manu Jain; Steve Wisseh; Steven M Rowe; Raouf S Amin; Scott H Donaldson; Peter R Durie; Karen S McCoy; Daniel B Rosenbluth; Inez Bronsveld; Frank J Accurso; Melissa A Ashlock; Michael W Konstan
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.
Thorax 2012;67(1):12-8.
2011: Jung Soo Suk; Benjamin Tang; Kanika Trehan; Pamela L Zeitlin; Nicholas J Boylan; Michael P Boyle; Mark J Cooper; Samuel Lai; Jung-Ming G Lin; Craig S Schneider; Justin Hanes
N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(11):1981-9.
2011: Natalie E West; Marsha E Davis; Noah Lechtzin; Christian A Merlo; Meghan Z Ramsay; Shane P Stenner; Jason B Turowski; Sharon L Watts; Michael P Boyle
Appropriate goal level for 25-hydroxyvitamin D in cystic fibrosis.
Chest 2011;140(2):469-74.
2011: Michelle NUTTALL Eakin; Peter J Mogayzel; Andrew Bilderback; Michael P Boyle; Kristin A Riekert
Longitudinal association between medication adherence and lung health in people with cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2011;10(4):258-64.
2011: Jung Soo Suk; Samuel Lai; Nicholas J Boylan; Michelle R Dawson; Michael P Boyle; Justin Hanes
Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine.
Nanomedicine (London, England) 2011;6(2):365-75.
2011: Kaoru Hida; Samuel Lai; Jung Soo Suk; Sang Y Won; Michael P Boyle; Justin Hanes
Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients.
PloS one 2011;6(5):e19919.
2010: Frank J Accurso; Steven M Rowe; J P Clancy; Michael P Boyle; Jordan M Dunitz; Peter Roy Durie; Scott D Sagel; Douglas B Hornick; Michael W Konstan; Scott H Donaldson; Richard B Moss; Joseph M Pilewski; Ronald C Rubenstein; Ahmet Z Uluer; Moira L Aitken; Steven D Freedman; Lynn M Rose; Nicole Mayer-Hamblett; Qunming Dong; Jiuhong Zha; Anne J Stone; Eric R Olson; Claudia L Ordoñez; Preston W Campbell; Melissa A Ashlock; Bonnie W Ramsey
Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation.
The New England journal of medicine 2010;363(21):1991-2003.
2010: Michael P Boyle
Cystic fibrosis: year in review.
Current opinion in pulmonary medicine 2010;16(6):583.
2010: Elliott C Dasenbrook; William Checkley; Christian A Merlo; Michael W Konstan; Noah Lechtzin; Michael P Boyle
Association between respiratory tract methicillin-resistant Staphylococcus aureus and survival in cystic fibrosis.
JAMA : the journal of the American Medical Association 2010;303(23):2386-92.
2010: Christopher R Sudfeld; Elliott C Dasenbrook; William G Merz; Karen C Carroll; Michael P Boyle
Prevalence and risk factors for recovery of filamentous fungi in individuals with cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2010;9(2):110-6.
2010: Avani C Modi; Alexandra L Quittner; Michael P Boyle
Assessing disease disclosure in adults with cystic fibrosis: the Adult Data for Understanding Lifestyle and Transitions (ADULT) survey Disclosure of disease in adults with cystic fibrosis.
BMC pulmonary medicine 2010;10():46.
2009: Benjamin Tang; Michelle Dawson; Samuel Lai; Ying-Ying Wang; Jung Soo Suk; Ming Yang; Pamela L Zeitlin; Michael P Boyle; Jie Fu; Justin Hanes
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19268-73.
2009: Jung Soo Suk; Samuel Lai; Ying-Ying Wang; Laura M Ensign; Pamela L Zeitlin; Michael P Boyle; Justin Hanes
The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.
Biomaterials 2009;30(13):2591-7.
2008: Elliott C Dasenbrook; Christian A Merlo; Marie Diener-West; Noah Lechtzin; Michael P Boyle
Persistent methicillin-resistant Staphylococcus aureus and rate of FEV1 decline in cystic fibrosis.
American journal of respiratory and critical care medicine 2008;178(8):814-21.
2008: Suzanne Elizabeth McLaughlin; Marie Diener-West; Alka Indurkhya; Haya Rubin; Rebekah Heckmann; Michael P Boyle
Improving transition from pediatric to adult cystic fibrosis care: lessons from a national survey of current practices.
Pediatrics 2008;121(5):e1160-6.
2007: Michael P Boyle
Adult cystic fibrosis.
JAMA : the journal of the American Medical Association 2007;298(15):1787-93.
2007: STEPHANIE HSU; Joshua D Groman; Christian A Merlo; Kathleen Naughton; Pamela L Zeitlin; Emily L Germain-Lee; Michael P Boyle; Garry R Cutting
Patients with mutations in Gsalpha have reduced activation of a downstream target in epithelial tissues due to haploinsufficiency.
The Journal of clinical endocrinology and metabolism 2007;92(10):3941-8.
2007: Christian A Merlo; Michael P Boyle; Marie Diener-West; Bruce C Marshall; Christopher H Goss; Noah Lechtzin
Incidence and risk factors for multiple antibiotic-resistant Pseudomonas aeruginosa in cystic fibrosis.
Chest 2007;132(2):562-8.
2007: Kristin A Riekert; Susan J Bartlett; Michael P Boyle; Jerry Krishnan; Cynthia S Rand
The association between depression, lung function, and health-related quality of life among adults with cystic fibrosis.
Chest 2007;132(1):231-7.
2007: Carlton K K Lee; Michael P Boyle; Marie Diener-West; Lois Brass-Ernst; Michelle Noschese; Pamela L Zeitlin
Levofloxacin pharmacokinetics in adult cystic fibrosis.
Chest 2007;131(3):796-802.
2007: Kitti Buranawuti; Michael P Boyle; Suzanne Cheng; Lori L Steiner; Kathryn McDougal; MARGARET D FALLIN; Christian A Merlo; Pamela L Zeitlin; Beryl J Rosenstein; Peter J Mogayzel; Xinjing Wang; Garry R Cutting
Variants in mannose-binding lectin and tumour necrosis factor alpha affect survival in cystic fibrosis.
Journal of medical genetics 2007;44(3):209-14.
2007: Michael P Boyle
Strategies for identifying modifier genes in cystic fibrosis.
Proceedings of the American Thoracic Society 2007;4(1):52-7.
2006: Michael P Boyle
Update on maintaining bone health in cystic fibrosis.
Current opinion in pulmonary medicine 2006;12(6):453-8.
2006: Jerry Wright; Christian A Merlo; Jeffrey B Reynolds; Pamela L Zeitlin; Joe G. N. Garcia; William B Guggino; Michael P Boyle
Respiratory epithelial gene expression in patients with mild and severe cystic fibrosis lung disease.
American journal of respiratory cell and molecular biology 2006;35(3):327-36.
2006: Michael P Boyle; Raymond A Enke; Jeffrey B Reynolds; Peter J Mogayzel; William B Guggino; Pamela L Zeitlin
Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia.
Virology journal 2006;3():29.
2006: Noah Lechtzin; Majnu John; Rafael A Irizarry; Christian A Merlo; Gregory B Diette; Michael P Boyle
Outcomes of adults with cystic fibrosis infected with antibiotic-resistant Pseudomonas aeruginosa.
Respiration; international review of thoracic diseases 2006;73(1):27-33.
2005: Michael P Boyle; Michelle L Noschese; Sharon L Watts; Marsha E Davis; Shane E Stenner; Noah Lechtzin
Failure of high-dose ergocalciferol to correct vitamin D deficiency in adults with cystic fibrosis.
American journal of respiratory and critical care medicine 2005;172(2):212-7.
2005: Robert M Aris; Peter A Merkel; Laura K Bachrach; Drucy Borowitz; Michael P Boyle; Sarah L Elkin; Theresa A Guise; Dana S Hardin; Charles S Haworth; Michael F Holick; Patricia M Joseph; Kimberly O'Brien; Elizabeth Tullis; Nelson B Watts; Terry B White
Guide to bone health and disease in cystic fibrosis.
The Journal of clinical endocrinology and metabolism 2005;90(3):1888-96.
2004: Pamela L Zeitlin; Michael P Boyle; William B Guggino; Luis Molina
A phase I trial of intranasal Moli1901 for cystic fibrosis.
Chest 2004;125(1):143-9.
2003: Michael P Boyle; Jonathan B Orens
Distal intestinal obstruction syndrome after surgery in cystic fibrosis.
Chest 2003;124(6):2408-9.
2003: Michael P Boyle
Nonclassic cystic fibrosis and CFTR-related diseases.
Current opinion in pulmonary medicine 2003;9(6):498-503.
2003: Michael P Boyle; Marie Diener-West; Laura J H Milgram; Michael Knowles; Carla Foy; Pamela L Zeitlin; Thomas A Standaert
A multicenter study of the effect of solution temperature on nasal potential difference measurements.
Chest 2003;124(2):482-9.
2003: Peter G Gibson; Peter A B Wark; Jodie L Simpson; Cliff Meldrum; S Meldrum; Nicholas Saltos; Michael P Boyle
Induced sputum IL-8 gene expression, neutrophil influx and MMP-9 in allergic bronchopulmonary aspergillosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;21(4):582-8.
2003: Christian A Merlo; Michael P Boyle
Modifier genes in cystic fibrosis lung disease.
The Journal of laboratory and clinical medicine 2003;141(4):237-41.
2003: Michael P Boyle; Raymond A Enke; Peter J Mogayzel; William B Guggino; Dana B Martin; Shikha Agarwal; Pamela L Zeitlin
Effect of adeno-associated virus-specific immunoglobulin G in human amniotic fluid on gene transfer.
Human gene therapy 2003;14(4):365-73.
2003: Michael P Boyle
So many drugs, so little time: the future challenge of cystic fibrosis care.
Chest 2003;123(1):3-5.
2002: Pamela L Zeitlin; Marie Diener-West; Ronald C Rubenstein; Michael P Boyle; Carlton K K Lee; Lois Brass-Ernst
Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(1):119-26.
2001: Michael P Boyle; Z Farukhi; M L Nosky
Strategies for improving transition to adult cystic fibrosis care, based on patient and parent views.
Pediatric pulmonology 2001;32(6):428-36.
2001: Michael P Boyle; Raymond A Enke; Robert J Adams; William B Guggino; Pamela L Zeitlin
In utero AAV-mediated gene transfer to rabbit pulmonary epithelium.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(2):115-21.
2001: Peadar G Noone; Nicole Hamblett; Frank J Accurso; Moira L Aitken; Michael P Boyle; Mark Dovey; Ron Gibson; C Johnson; D Kellerman; Michael W Konstan; Laura J H Milgram; J Mundahl; G Retsch-Bogort; D Rodman; J Williams-Warren; Robert W Wilmott; Pamela L Zeitlin; Bonnie W Ramsey
Safety of aerosolized INS 365 in patients with mild to moderate cystic fibrosis: results of a phase I multi-center study.
Pediatric pulmonology 2001;32(2):122-8.
2001: Michael P Boyle
The spectrum of CFTR-related disease.
Internal medicine (Tokyo, Japan) 2001;40(6):522-5.
2001: Michael P Boyle
Minocycline-induced pancreatitis in cystic fibrosis.
Chest 2001;119(4):1283-5.
2000: Michael P Boyle
Unique presentations and chronic complications in adult cystic fibrosis: do they teach us anything about CFTR?
Respiratory research 2000;1(3):133-5.
1993: Michael P Boyle; H F Weisman
Limitation of infarct expansion and ventricular remodeling by late reperfusion. Study of time course and mechanism in a rat model.
Circulation 1993;88(6):2872-83.
1990: H F Weisman; T Bartow; Michelle K Leppo; Henry C Marsh; G R Carson; M F Concino; Michael P Boyle; K H Roux; Myron L Weisfeldt; D T Fearon
Soluble human complement receptor type 1: in vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis.
Science (New York, N.Y.) 1990;249(4965):146-51.
1990: H F Weisman; T Bartow; Michelle K Leppo; Michael P Boyle; Henry C Marsh; G R Carson; K H Roux; Myron L Weisfeldt; D T Fearon
Recombinant soluble CR1 suppressed complement activation, inflammation, and necrosis associated with reperfusion of ischemic myocardium.
Transactions of the Association of American Physicians 1990;103():64-72.