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Lotte Vogel

Research Profile

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Brian R Larsen; Chen-Yong Lin; Nis V L Nielsen; Annika W Nonboe; Steen S Poulsen; Hanne Skovbjerg; Christoffer Soendergaard; Simon D R Steffensen; Roman Szabo; Martin N Andersen; Jette Bornholdt; Thomas H Bugge; Stine Friis; Sine Godiksen; Jan K Jensen; Lotte K Vogel
Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase.
Roman Szabo; Katiuchia Uzzun Sales; Lotte K Vogel; Eric Camerer; Stine Friis; Sine Godiksen; J Silvio Gutkind; Karina K Hansen; Edith Hummler; Peter Kosa; Natalia A Shylo; Thomas H Bugge
Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation.
Stine Friis; Sine Godiksen; Jette Bornholdt; Joanna Selzer-Plon; Hanne B Rasmussen; Thomas H Bugge; Chen-Yong Lin; Lotte K Vogel
Transport via the transcytotic pathway makes prostasin available as a substrate for matriptase.

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All Publications

2013: Brian R Larsen; Chen-Yong Lin; Nis V L Nielsen; Annika W Nonboe; Steen S Poulsen; Hanne Skovbjerg; Christoffer Soendergaard; Simon D R Steffensen; Roman Szabo; Martin N Andersen; Jette Bornholdt; Thomas H Bugge; Stine Friis; Sine Godiksen; Jan K Jensen; Lotte K Vogel
Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase.
Experimental cell research 2013;319(6):918-29.
2012: Roman Szabo; Katiuchia Uzzun Sales; Lotte K Vogel; Eric Camerer; Stine Friis; Sine Godiksen; J Silvio Gutkind; Karina K Hansen; Edith Hummler; Peter Kosa; Natalia A Shylo; Thomas H Bugge
Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation.
PLoS genetics 2012;8(8):e1002937.
2011: Stine Friis; Sine Godiksen; Jette Bornholdt; Joanna Selzer-Plon; Hanne B Rasmussen; Thomas H Bugge; Chen-Yong Lin; Lotte K Vogel
Transport via the transcytotic pathway makes prostasin available as a substrate for matriptase.
The Journal of biological chemistry 2011;286(7):5793-802.
2011: Nuno T Marcos; Eric P Bennett; Joana Gomes; Ana Magalhaes; Catarina Gomes; Leonor David; Imran Dar; Charlotte Jeanneau; Shawn DeFrees; Dorrit Krustrup; Lotte K Vogel; Elin H Kure; Joy Burchell; Joyce Taylor-Papadimitriou; Henrik Clausen; Ulla Mandel; Celso A Reis
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.
Frontiers in bioscience (Elite edition) 2011;3():1443-55.
2011: Jette Bornholdt; Stine Friis; Sine Godiksen; Steen S Poulsen; Eric Santoni-Rugiu; Hanne C Bisgaard; Inger M B Lothe; Tone Ikdahl; Kjell Magne Tveit; Egil Johnson; Elin H Kure; Lotte K Vogel
The level of claudin-7 is reduced as an early event in colorectal carcinogenesis.
BMC cancer 2011;11():65.
2011: Anders Lorentzen; Rikke H Lewinsky; Jette Bornholdt; Lotte K Vogel; Cathy Mitchelmore
Expression profile of the N-myc Downstream Regulated Gene 2 (NDRG2) in human cancers with focus on breast cancer.
BMC cancer 2011;11():14.
2010: Hanna Wallin; Maria Bjarnadottir; Lotte K Vogel; Johan Wassélius; Ulf Ekström; Magnus Abrahamson
Cystatins--Extra- and intracellular cysteine protease inhibitors: High-level secretion and uptake of cystatin C in human neuroblastoma cells.
Biochimie 2010;92(11):1625-34.
2009: Joanna Selzer-Plon; Jette Bornholdt; Stine Friis; Hanne C Bisgaard; Inger Mb Lothe; Kjell Magne Tveit; Elin H Kure; Ulla Vogel; Lotte K Vogel
Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis.
BMC cancer 2009;9():201.
2009: Hanne Skovbjerg; Dorit Anthonsen; Inger M B Lothe; Kjell Magne Tveit; Elin H Kure; Lotte K Vogel
Collagen mRNA levels changes during colorectal cancer carcinogenesis.
BMC cancer 2009;9():136.
2008: Paola Mina-Osorio; Beata McAuliffe; Catherine O'Conor; Christina L Grant; Lotte K Vogel; Daniel Rodriguez-Pinto; Kathryn V Holmes; Enrique Ortega; Linda H. Shapiro
CD13 is a novel mediator of monocytic/endothelial cell adhesion.
Journal of leukocyte biology 2008;84(2):448-59.
2008: Sine Godiksen; Joanna Selzer-Plon; Esben D K Pedersen; Kathrine Abell; Hanne B Rasmussen; Roman Szabo; Thomas H Bugge; Lotte K Vogel
Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary.
The Biochemical journal 2008;413(2):251-9.
2007: Anders Lorentzen; Lotte K Vogel; Rikke H Lewinsky; Mona Saebø; Camilla Furu Skjelbred; Sine Godiksen; Geir Hoff; Kjell Magne Tveit; Inger Marie Bowitz Lothe; Tone Ikdahl; Elin H Kure; Cathy Mitchelmore
Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma.
BMC cancer 2007;7():192.
2006: Marie-Thérèse Bawolak; Jean-Philippe Fortin; Lotte K Vogel; Albert Adam; Francois Marceau
The bradykinin B2 receptor antagonist icatibant (Hoe 140) blocks aminopeptidase N at micromolar concentrations: off-target alterations of signaling mediated by the bradykinin B1 and angiotensin receptors.
European journal of pharmacology 2006;551(1-3):108-11.
2006: Patrick M L Vanderheyden; Heidi Demaegdt; Julie Swales; Pieter-Jan Lenaerts; Jean-Paul De Backer; Lotte K Vogel; Georges Vauquelin
Synergistic inhibition of the enzymatic activity of aminopeptidase N by divalent metal ion chelators.
Fundamental & clinical pharmacology 2006;20(6):613-9.
2006: Heidi Demaegdt; Pieter-Jan Lenaerts; Julie Swales; Jean-Paul De Backer; Hilde Laeremans; Minh Tam Le; Ken Kersemans; Lotte K Vogel; Yvette Michotte; Patrick M L Vanderheyden; Georges Vauquelin
Angiotensin AT4 receptor ligand interaction with cystinyl aminopeptidase and aminopeptidase N: [125I]Angiotensin IV only binds to the cystinyl aminopeptidase apo-enzyme.
European journal of pharmacology 2006;546(1-3):19-27.
2006: Lotte K Vogel; Mona Saebø; Camilla Furu Skjelbred; Kathrine Abell; Esben D K Pedersen; Ulla Vogel; Elin H Kure
The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals.
BMC cancer 2006;6():176.
2005: Lotte K Vogel; Jakob E Larsen; Martin Hansen; Renato Truffer
Conversion of proteins from a non-polarized to an apical secretory pattern in MDCK cells.
Biochemical and biophysical research communications 2005;330(3):665-72.
2004: Thomas Jespersen; Hanne B Rasmussen; Morten Grunnet; Henrik Sindal Jensen; Kamilla Angelo; Delphine S Dupuis; Lotte K Vogel; Nanna K Jorgensen; Dan A Klaerke; Søren-Peter Olesen
Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.
Journal of cell science 2004;117(Pt 19):4517-26.
2003: Jamie J Breslin; Irene Mørk; M K Smith; Lotte K Vogel; Erin M Hemmila; Aurelio Bonavia; Pierre J Talbot; Hans Sjöström; Ove Norén; Kathryn V Holmes
Human coronavirus 229E: receptor binding domain and neutralization by soluble receptor at 37 degrees C.
Journal of virology 2003;77(7):4435-8.
2002: Jakob E Larsen; Hans Sjöström; Ove Norén; Lotte K Vogel
Serpins are apically secreted from MDCK cells independently of their raft association.
Biochemical and biophysical research communications 2002;299(1):35-41.
2002: Lotte K Vogel; Sia Sahkri; Hans Sjostrom; Ove Noren; Martin Spiess
Secretion of antithrombin is converted from nonpolarized to apical by exchanging its amino terminus for that of apically secreted family members.
The Journal of biological chemistry 2002;277(16):13883-8.
2000: Lotte K Vogel; Jakob E Larsen
Apical and non-polarized secretion of serpins from MDCK cells.
FEBS letters 2000;473(3):297-302.
2000: Anja Renold; R Cescato; Nicole Beuret; Lotte K Vogel; J M Wahlberg; J L Brown; Klaus Fiedler; Martin Spiess
Basolateral sorting signals differ in their ability to redirect apical proteins to the basolateral cell surface.
The Journal of biological chemistry 2000;275(13):9290-5.
1999: Jakob E Larsen; George V Avvakumov; Geoffrey L Hammond; Lotte K Vogel
N-glycans are not the signal for apical sorting of corticosteroid binding globulin in MDCK cells.
FEBS letters 1999;451(1):19-22.
1998: Gert H Hansen; Bernard Delmas; L Besnardeau; Lotte K Vogel; Hubert Laude; Hans Sjöström; Ove Norén
The coronavirus transmissible gastroenteritis virus causes infection after receptor-mediated endocytosis and acid-dependent fusion with an intracellular compartment.
Journal of virology 1998;72(1):527-34.
1997: K Norén; Gert H Hansen; H Clausen; Ove Norén; Hans Sjöström; Lotte K Vogel
Defectively N-glycosylated and non-O-glycosylated aminopeptidase N (CD13) is normally expressed at the cell surface and has full enzymatic activity.
Experimental cell research 1997;231(1):112-8.
1996: C Lerche; Lotte K Vogel; Linda H. Shapiro; Ove Norén; Hans Sjöström
Human aminopeptidase N is encoded by 20 exons.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(9):712-3.
1995: Lotte K Vogel; Ove Norén; Hans Sjöström
Transcytosis of aminopeptidase N in Caco-2 cells is mediated by a non-cytoplasmic signal.
The Journal of biological chemistry 1995;270(39):22933-8.
1993: Lotte K Vogel; G Suske; M Beato; Ove Norén; Hans Sjöström
Uteroglobin, an apically secreted protein of the uterine epithelium, is secreted non-polarized form MDCK cells and mainly basolaterally from Caco-2 cells.
FEBS letters 1993;330(3):293-6.
1992: Lotte K Vogel; Ove Norén; Hans Sjöström
The apical sorting signal on human aminopeptidase N is not located in the stalk but in the catalytic head group.
FEBS letters 1992;308(1):14-7.
1992: Bernard Delmas; Jacqueline Gelfi; R L'Haridon; Lotte K Vogel; Hans Sjöström; Ove Norén; Hubert Laude
Aminopeptidase N is a major receptor for the entero-pathogenic coronavirus TGEV.
Nature 1992;357(6377):417-20.
1992: Lotte K Vogel; M Spiess; Hans Sjöström; Ove Norén
Evidence for an apical sorting signal on the ectodomain of human aminopeptidase N.
The Journal of biological chemistry 1992;267(4):2794-7.