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Bert Vogelstein

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Disorders

Physiology

Mutation

Chemicals & Drugs

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Molecular Sequence Data

Anatomy

Living Beings

Mice

Procedures

Polymerase Chain Reaction

Genes & Molecular Sequences

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Publications

TOP 3
Mandelker Diana; Gabelli Sandra B; Schmidt-Kittler Oleg; Zhu Jiuxiang; Cheong Ian; Huang Chuan-Hsiang; Kinzler Kenneth W; Vogelstein Bert; Amzel L Mario
A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane.
Li Meng; Chen Wei-Dong; Papadopoulos Nickolas; Goodman Steven N; Bjerregaard Niels Christian; Laurberg Søren; Levin Bernard; Juhl Hartmut; Arber Nadir; Moinova Helen; Durkee Kris; Schmidt Kerstin; He Yiping; Diehl Frank; Velculescu Victor E; Zhou Shibin; Diaz Luis A; Kinzler Kenneth W; Markowitz Sanford D; Vogelstein Bert
Sensitive digital quantification of DNA methylation in clinical samples.
Yun Jihye; Rago Carlo; Cheong Ian; Pagliarini Ray; Angenendt Philipp; Rajagopalan Harith; Schmidt Kerstin; Willson James K V; Markowitz Sandy; Zhou Shibin; Diaz Luis A; Velculescu Victor E; Lengauer Christoph; Kinzler Kenneth W; Vogelstein Bert; Papadopoulos Nickolas
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.

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All Publications

2009: Mandelker Diana; Gabelli Sandra B; Schmidt-Kittler Oleg; Zhu Jiuxiang; Cheong Ian; Huang Chuan-Hsiang; Kinzler Kenneth W; Vogelstein Bert; Amzel L Mario
A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(40):16996-7001.
2009: Li Meng; Chen Wei-Dong; Papadopoulos Nickolas; Goodman Steven N; Bjerregaard Niels Christian; Laurberg Søren; Levin Bernard; Juhl Hartmut; Arber Nadir; Moinova Helen; Durkee Kris; Schmidt Kerstin; He Yiping; Diehl Frank; Velculescu Victor E; Zhou Shibin; Diaz Luis A; Kinzler Kenneth W; Markowitz Sanford D; Vogelstein Bert
Sensitive digital quantification of DNA methylation in clinical samples.
Nature biotechnology 2009;27(9):858-63.
2009: Yun Jihye; Rago Carlo; Cheong Ian; Pagliarini Ray; Angenendt Philipp; Rajagopalan Harith; Schmidt Kerstin; Willson James K V; Markowitz Sandy; Zhou Shibin; Diaz Luis A; Velculescu Victor E; Lengauer Christoph; Kinzler Kenneth W; Vogelstein Bert; Papadopoulos Nickolas
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
Science (New York, N.Y.) 2009;325(5947):1555-9.
2009: Carter Hannah; Chen Sining; Isik Leyla; Tyekucheva Svitlana; Velculescu Victor E; Kinzler Kenneth W; Vogelstein Bert; Karchin Rachel
Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations.
Cancer research 2009;69(16):6660-7.
2009: Guda Kishore; Moinova Helen; He Jian; Jamison Oliver; Ravi Lakshmeswari; Natale Leanna; Lutterbaugh James; Lawrence Earl; Lewis Susan; Willson James K V; Lowe John B; Wiesner Georgia L; Parmigiani Giovanni; Barnholtz-Sloan Jill; Dawson Dawn W; Velculescu Victor E; Kinzler Kenneth W; Papadopoulos Nikolas; Vogelstein Bert; Willis Joseph; Gerken Thomas A; Markowitz Sanford D
Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12921-5.
2009: Blackford Amanda; Serrano Oscar K; Wolfgang Christopher L; Parmigiani Giovanni; Jones Siân; Zhang Xiaosong; Parsons D Williams; Lin Jimmy Cheng-Ho; Leary Rebecca J; Eshleman James R; Goggins Michael; Jaffee Elizabeth M; Iacobuzio-Donahue Christine A; Maitra Anirban; Cameron John L; Olino Kelly; Schulick Richard; Winter Jordan; Herman Joseph M; Laheru Daniel; Klein Alison P; Vogelstein Bert; Kinzler Kenneth W; Velculescu Victor E; Hruban Ralph H
SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(14):4674-9.
2009: Blackford Amanda; Parmigiani Giovanni; Kensler Thomas W; Wolfgang Christopher; Jones Siân; Zhang Xiaosong; Parsons D Willams; Lin Jimmy Cheng-Ho; Leary Rebecca J; Eshleman James R; Goggins Michael; Jaffee Elizabeth M; Iacobuzio-Donahue Christine A; Maitra Anirban; Klein Alison; Cameron John L; Olino Kelly; Schulick Richard; Winter Jordan; Vogelstein Bert; Velculescu Victor E; Kinzler Kenneth W; Hruban Ralph H
Genetic mutations associated with cigarette smoking in pancreatic cancer.
Cancer research 2009;69(8):3681-8.
2009: Jones Siân; Hruban Ralph H; Kamiyama Mihoko; Borges Michael; Zhang Xiaosong; Parsons D Williams; Lin Jimmy Cheng-Ho; Palmisano Emily; Brune Kieran; Jaffee Elizabeth M; Iacobuzio-Donahue Christine A; Maitra Anirban; Parmigiani Giovanni; Kern Scott E; Velculescu Victor E; Kinzler Kenneth W; Vogelstein Bert; Eshleman James R; Goggins Michael; Klein Alison P
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.
Science (New York, N.Y.) 2009;324(5924):217.
2009: Sur Surojit; Pagliarini Raymond; Bunz Fred; Rago Carlo; Diaz Luis A; Kinzler Kenneth W; Vogelstein Bert; Papadopoulos Nickolas
A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3964-9.
2009: Yan Hai; Parsons D Williams; Jin Genglin; McLendon Roger; Rasheed B Ahmed; Yuan Weishi; Kos Ivan; Batinic-Haberle Ines; Jones Siân; Riggins Gregory J; Friedman Henry; Friedman Allan; Reardon David; Herndon James; Kinzler Kenneth W; Velculescu Victor E; Vogelstein Bert; Bigner Darell D
IDH1 and IDH2 mutations in gliomas.
The New England journal of medicine 2009;360(8):765-73.
2009: Parmigiani Giovanni; Boca Simina; Lin Jimmy; Kinzler Kenneth W; Velculescu Victor; Vogelstein Bert
Design and analysis issues in genome-wide somatic mutation studies of cancer.
Genomics 2009;93(1):17-21.
2009: Duncan Christopher G; Leary Rebecca J; Lin Jimmy Cheng-Ho; Cummins Jordan; Di Chunhui; Schaefer Carl F; Wang Tian-Li; Riggins Gregory J; Edwards Jennifer; Bigner Darell; Kopelovich Levy; Vogelstein Bert; Kinzler Kenneth W; Velculescu Victor E; Yan Hai
Identification of microbial DNA in human cancer.
BMC medical genomics 2009;2():22.
2008: He Yiping; Vogelstein Bert; Velculescu Victor E; Papadopoulos Nickolas; Kinzler Kenneth W
The antisense transcriptomes of human cells.
Science (New York, N.Y.) 2008;322(5909):1855-7.
2008: Leary Rebecca J; Lin Jimmy C; Cummins Jordan; Boca Simina; Wood Laura D; Parsons D Williams; Jones Siân; Sjöblom Tobias; Park Ben-Ho; Parsons Ramon; Willis Joseph; Dawson Dawn; Willson James K V; Nikolskaya Tatiana; Nikolsky Yuri; Kopelovich Levy; Papadopoulos Nick; Pennacchio Len A; Wang Tian-Li; Markowitz Sanford D; Parmigiani Giovanni; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16224-9.
2008: Jones Siân; Zhang Xiaosong; Parsons D Williams; Lin Jimmy Cheng-Ho; Leary Rebecca J; Angenendt Philipp; Mankoo Parminder; Carter Hannah; Kamiyama Hirohiko; Jimeno Antonio; Hong Seung-Mo; Fu Baojin; Lin Ming-Tseh; Calhoun Eric S; Kamiyama Mihoko; Walter Kimberly; Nikolskaya Tatiana; Nikolsky Yuri; Hartigan James; Smith Douglas R; Hidalgo Manuel; Leach Steven D; Klein Alison P; Jaffee Elizabeth M; Goggins Michael; Maitra Anirban; Iacobuzio-Donahue Christine; Eshleman James R; Kern Scott E; Hruban Ralph H; Karchin Rachel; Papadopoulos Nickolas; Parmigiani Giovanni; Vogelstein Bert; Velculescu Victor E; Kinzler Kenneth W
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.
Science (New York, N.Y.) 2008;321(5897):1801-6.
2008: Parsons D Williams; Jones Siân; Zhang Xiaosong; Lin Jimmy Cheng-Ho; Leary Rebecca J; Angenendt Philipp; Mankoo Parminder; Carter Hannah; Siu I-Mei; Gallia Gary L; Olivi Alessandro; McLendon Roger; Rasheed B Ahmed; Keir Stephen; Nikolskaya Tatiana; Nikolsky Yuri; Busam Dana A; Tekleab Hanna; Diaz Luis A; Hartigan James; Smith Doug R; Strausberg Robert L; Marie Suely Kazue Nagahashi; Shinjo Sueli Mieko Oba; Yan Hai; Riggins Gregory J; Bigner Darell D; Karchin Rachel; Papadopoulos Nick; Parmigiani Giovanni; Vogelstein Bert; Velculescu Victor E; Kinzler Kenneth W
An integrated genomic analysis of human glioblastoma multiforme.
Science (New York, N.Y.) 2008;321(5897):1807-12.
2008: Diehl Frank; Schmidt Kerstin; Choti Michael A; Romans Katharine; Goodman Steven; Li Meng; Thornton Katherine; Agrawal Nishant; Sokoll Lori; Szabo Steve A; Kinzler Kenneth W; Vogelstein Bert; Diaz Luis A
Circulating mutant DNA to assess tumor dynamics.
Nature medicine 2008;14(9):985-90.
2008: Amzel L Mario; Huang Chuan-Hsiang; Mandelker Diana; Lengauer Christoph; Gabelli Sandra B; Vogelstein Bert
Structural comparisons of class I phosphoinositide 3-kinases.
Nature reviews. Cancer 2008;8(9):665-9.
2008: Frazzetto Mark; Suphioglu Cenk; Zhu Jiuxiang; Schmidt-Kittler Oleg; Jennings Ian G; Cranmer Susan L; Jackson Shaun P; Kinzler Kenneth W; Vogelstein Bert; Thompson Philip E
Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket.
The Biochemical journal 2008;414(3):383-90.
2008: Diehl Frank; Schmidt Kerstin; Durkee Kristine H; Moore Kent J; Goodman Steve N; Shuber Anthony P; Kinzler Kenneth W; Vogelstein Bert
Analysis of mutations in DNA isolated from plasma and stool of colorectal cancer patients.
Gastroenterology 2008;135(2):489-98.
2008: Jones Siân; Chen Wei-Dong; Parmigiani Giovanni; Diehl Frank; Beerenwinkel Niko; Antal Tibor; Traulsen Arne; Nowak Martin A; Siegel Christopher; Velculescu Victor E; Kinzler Kenneth W; Vogelstein Bert; Willis Joseph; Markowitz Sanford D
Comparative lesion sequencing provides insights into tumor evolution.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4283-8.
2008: Barber Thomas D; McManus Kirk; Yuen Karen W Y; Reis Marcelo; Parmigiani Giovanni; Shen Dong; Barrett Irene; Nouhi Yasaman; Spencer Forrest; Markowitz Sanford; Velculescu Victor E; Kinzler Kenneth W; Vogelstein Bert; Lengauer Christoph; Hieter Philip
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(9):3443-8.
2008: Segal Neil H; Parsons D Williams; Peggs Karl S; Velculescu Victor; Kinzler Ken W; Vogelstein Bert; Allison James P
Epitope landscape in breast and colorectal cancer.
Cancer research 2008;68(3):889-92.
2008: Picelli Simone; Vandrovcova Jana; Jones Siân; Djureinovic Tatjana; Skoglund Johanna; Zhou Xiao-Lei; Velculescu Victor E; Vogelstein Bert; Lindblom Annika
Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q.
BMC cancer 2008;8():87.
2007: Huang Chuan-Hsiang; Mandelker Diana; Schmidt-Kittler Oleg; Samuels Yardena; Velculescu Victor E; Kinzler Kenneth W; Vogelstein Bert; Gabelli Sandra B; Amzel L Mario
The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations.
Science (New York, N.Y.) 2007;318(5857):1744-8.
2007: Beerenwinkel Niko; Antal Tibor; Dingli David; Traulsen Arne; Kinzler Kenneth W; Velculescu Victor E; Vogelstein Bert; Nowak Martin A
Genetic progression and the waiting time to cancer.
PLoS computational biology 2007;3(11):e225.
2007: Wood Laura D; Parsons D Williams; Jones Siân; Lin Jimmy; Sjöblom Tobias; Leary Rebecca J; Shen Dong; Boca Simina M; Barber Thomas; Ptak Janine; Silliman Natalie; Szabo Steve; Dezso Zoltan; Ustyanksky Vadim; Nikolskaya Tatiana; Nikolsky Yuri; Karchin Rachel; Wilson Paul A; Kaminker Joshua S; Zhang Zemin; Croshaw Randal; Willis Joseph; Dawson Dawn; Shipitsin Michail; Willson James K V; Sukumar Saraswati; Polyak Kornelia; Park Ben Ho; Pethiyagoda Charit L; Pant P V Krishna; Ballinger Dennis G; Sparks Andrew B; Hartigan James; Smith Douglas R; Suh Erick; Papadopoulos Nickolas; Buckhaults Phillip; Markowitz Sanford D; Parmigiani Giovanni; Kinzler Kenneth W; Velculescu Victor E; Vogelstein Bert
The genomic landscapes of human breast and colorectal cancers.
Science (New York, N.Y.) 2007;318(5853):1108-13.
2007: Rago Carlo; Huso David L; Diehl Frank; Karim Baktiar; Liu Guosheng; Papadopoulos Nickolas; Samuels Yardena; Velculescu Victor E; Vogelstein Bert; Kinzler Kenneth W; Diaz Luis A
Serial assessment of human tumor burdens in mice by the analysis of circulating DNA.
Cancer research 2007;67(19):9364-70.
2007: Lin Jimmy; Gan Christine M; Zhang Xiaosong; Jones Siân; Sjöblom Tobias; Wood Laura D; Parsons D Williams; Papadopoulos Nickolas; Kinzler Kenneth W; Vogelstein Bert; Parmigiani Giovanni; Velculescu Victor E
A multidimensional analysis of genes mutated in breast and colorectal cancers.
Genome research 2007;17(9):1304-18.
2007: Plomp Marco; McCaffery J Michael; Cheong Ian; Huang Xin; Bettegowda Chetan; Kinzler Kenneth W; Zhou Shibin; Vogelstein Bert; Malkin Alexander J
Spore coat architecture of Clostridium novyi NT spores.
Journal of bacteriology 2007;189(17):6457-68.
2007: Zhang Xiaosong; Zhao Ming; Rudek Michelle A; He Ping; Vogelstein Bert
Development and validation of a liquid chromatography/tandem mass spectrometry method for the determination of DMXAA in human and mouse plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;852(1-2):217-22.
2007: Zhang Xiaodong; Guo Ailan; Yu Jianshi; Possemato Anthony; Chen Yueting; Zheng Weiping; Polakiewicz Roberto D; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E; Wang Zhenghe John
Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):4060-4.
2007: Lagerstedt Robinson Kristina; Liu Tao; Vandrovcova Jana; Halvarsson Britta; Clendenning Mark; Frebourg Thierry; Papadopoulos Nickolas; Kinzler Kenneth W; Vogelstein Bert; Peltomäki Päivi; Kolodner Richard D; Nilbert Mef; Lindblom Annika
Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics.
Journal of the National Cancer Institute 2007;99(4):291-9.
2007: Wei Ming Q; Ellem Kay A O; Dunn Paul; West Malcolm J; Bai Chun Xue; Vogelstein Bert
Facultative or obligate anaerobic bacteria have the potential for multimodality therapy of solid tumours.
European journal of cancer (Oxford, England : 1990) 2007;43(3):490-6.
2007: Rago Carlo; Vogelstein Bert; Bunz Fred
Genetic knockouts and knockins in human somatic cells.
Nature protocols 2007;2(11):2734-46.
2007: Diaz Luis A; Foss Catherine A; Thornton Katherine; Nimmagadda Sridhar; Endres Christopher J; Uzuner Ovsev; Seyler Thorsten M; Ulrich Slif D; Conway Janet; Bettegowda Chetan; Agrawal Nishant; Cheong Ian; Zhang Xiaosong; Ladenson Paul W; Vogelstein Barry N; Mont Michael A; Zhou Shibin; Kinzler Kenneth W; Vogelstein Bert; Pomper Martin G
Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT.
PloS one 2007;2(10):e1007.
2007: Diaz Luis A; Foss Catherine A; Thornton Katherine; Nimmagadda Sridhar; Endres Christopher J; Uzuner Ovsev; Seyler Thorsten M; Ulrich Slif D; Conway Janet; Bettegowda Chetan; Agrawal Nishant; Cheong Ian; Zhang Xiaosong; Ladenson Paul W; Vogelstein Barry N; Mont Michael A; Zhou Shibin; Kinzler Kenneth W; Vogelstein Bert; Pomper Martin G
Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT.
PloS one 2007;2(10):e1007.
2007: Luo Jinyong; Deng Zhong-Liang; Luo Xiaoji; Tang Ni; Song Wen-Xin; Chen Jin; Sharff Katie A; Luu Hue H; Haydon Rex C; Kinzler Kenneth W; Vogelstein Bert; He Tong-Chuan
A protocol for rapid generation of recombinant adenoviruses using the AdEasy system.
Nature protocols 2007;2(5):1236-47.
2006: Bettegowda Chetan; Huang Xin; Lin Jimmy; Cheong Ian; Kohli Manu; Szabo Stephen A; Zhang Xiaosong; Diaz Luis A; Velculescu Victor E; Parmigiani Giovanni; Kinzler Kenneth W; Vogelstein Bert; Zhou Shibin
The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT.
Nature biotechnology 2006;24(12):1573-80.
2006: Cheong Ian; Huang Xin; Bettegowda Chetan; Diaz Luis A; Kinzler Kenneth W; Zhou Shibin; Vogelstein Bert
A bacterial protein enhances the release and efficacy of liposomal cancer drugs.
Science (New York, N.Y.) 2006;314(5803):1308-11.
2006: Sjöblom Tobias; Jones Siân; Wood Laura D; Parsons D Williams; Lin Jimmy; Barber Thomas D; Mandelker Diana; Leary Rebecca J; Ptak Janine; Silliman Natalie; Szabo Steve; Buckhaults Phillip; Farrell Christopher; Meeh Paul; Markowitz Sanford D; Willis Joseph; Dawson Dawn; Willson James K V; Gazdar Adi F; Hartigan James; Wu Leo; Liu Changsheng; Parmigiani Giovanni; Park Ben Ho; Bachman Kurtis E; Papadopoulos Nickolas; Vogelstein Bert; Kinzler Kenneth W; Velculescu Victor E
The consensus coding sequences of human breast and colorectal cancers.
Science (New York, N.Y.) 2006;314(5797):268-74.
2006: Wood Laura D; Calhoun Eric S; Silliman Natalie; Ptak Janine; Szabo Steve; Powell Steve M; Riggins Gregory J; Wang Tian-Li; Yan Hai; Gazdar Adi; Kern Scott E; Pennacchio Len; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.
Human mutation 2006;27(10):1060-1.
2006: Papadopoulos Nickolas; Kinzler Kenneth W; Vogelstein Bert
The role of companion diagnostics in the development and use of mutation-targeted cancer therapies.
Nature biotechnology 2006;24(8):985-95.
2006: Diehl Frank; Li Meng; He Yiping; Kinzler Kenneth W; Vogelstein Bert; Dressman Devin
BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions.
Nature methods 2006;3(7):551-9.
2006: McDonald Donald; Vogelstein Bert; King Marie-Claire; Hong Waun Ki; Augustin Hellmut; Hanahan Douglas; Lippman Marc
Wanted: cancer boss.
Nature 2006;440(7087):978-9.
2006: Cummins Jordan M; He Yiping; Leary Rebecca J; Pagliarini Ray; Diaz Luis A; Sjoblom Tobias; Barad Omer; Bentwich Zvi; Szafranska Anna E; Labourier Emmanuel; Raymond Christopher K; Roberts Brian S; Juhl Hartmut; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
The colorectal microRNAome.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3687-92.
2006: Nanda Akash; Karim Baktiar; Peng Zhongsheng; Liu Guosheng; Qiu Weiping; Gan Christine; Vogelstein Bert; St Croix Brad; Kinzler Kenneth W; Huso David L
Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3351-6.
2006: Li Meng; Diehl Frank; Dressman Devin; Vogelstein Bert; Kinzler Kenneth W
BEAMing up for detection and quantification of rare sequence variants.
Nature methods 2006;3(2):95-7.
2005: Diaz Luis A; Cheong Ian; Foss Catherine A; Zhang Xiaosong; Peters Brock A; Agrawal Nishant; Bettegowda Chetan; Karim Baktiar; Liu Guosheng; Khan Khalid; Huang Xin; Kohli Manu; Dang Long H; Hwang Paul; Vogelstein Ahava; Garrett-Mayer Elizabeth; Kobrin Barry; Pomper Martin; Zhou Shibin; Kinzler Kenneth W; Vogelstein Bert; Huso David L
Pharmacologic and toxicologic evaluation of C. novyi-NT spores.
Toxicological sciences : an official journal of the Society of Toxicology 2005;88(2):562-75.
2005: Diehl Frank; Li Meng; Dressman Devin; He Yiping; Shen Dong; Szabo Steve; Diaz Luis A; Goodman Steven N; David Kerstin A; Juhl Hartmut; Kinzler Kenneth W; Vogelstein Bert
Detection and quantification of mutations in the plasma of patients with colorectal tumors.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16368-73.
2005: Parsons D Williams; Wang Tian-Li; Samuels Yardena; Bardelli Alberto; Cummins Jordan M; DeLong Laura; Silliman Natalie; Ptak Janine; Szabo Steve; Willson James K V; Markowitz Sanford; Kinzler Kenneth W; Vogelstein Bert; Lengauer Christoph; Velculescu Victor E
Colorectal cancer: mutations in a signalling pathway.
Nature 2005;436(7052):792.
2005: Smith Amos B; Freeze B Scott; LaMarche Matthew J; Sager Jason; Kinzler Kenneth W; Vogelstein Bert
Discodermolide analogues as the chemical component of combination bacteriolytic therapy.
Bioorganic & medicinal chemistry letters 2005;15(15):3623-6.
2005: Bachman Kurtis E; Sager Jason; Cheong Ian; Catto Marco; Bardelli Alberto; Park Ben Ho; Vogelstein Bert; Carotti Angelo; Kinzler Kenneth W; Lengauer Christoph
Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells.
Molecular cancer therapeutics 2005;4(6):1026-30.
2005: Samuels Yardena; Diaz Luis A; Schmidt-Kittler Oleg; Cummins Jordan M; Delong Laura; Cheong Ian; Rago Carlo; Huso David L; Lengauer Christoph; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
Mutant PIK3CA promotes cell growth and invasion of human cancer cells.
Cancer cell 2005;7(6):561-73.
2005: Hienonen Tuija; Sammalkorpi Heli; Enholm Susa; Alhopuro Pia; Barber Thomas D; Lehtonen Rainer; Nupponen Nina N; Lehtonen Heli; Salovaara Reijo; Mecklin Jukka-Pekka; Järvinen Heikki; Koistinen Riitta; Arango Diego; Launonen Virpi; Vogelstein Bert; Karhu Auli; Aaltonen Lauri A
Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers.
Cancer research 2005;65(11):4607-13.
2005: Peters Brock A; Diaz Luis A; Polyak Kornelia; Meszler Leslie; Romans Kathy; Guinan Eva C; Antin Joseph H; Myerson David; Hamilton Stanley R; Vogelstein Bert; Kinzler Kenneth W; Lengauer Christoph
Contribution of bone marrow-derived endothelial cells to human tumor vasculature.
Nature medicine 2005;11(3):261-2.
2005: Michor Franziska; Iwasa Yoh; Vogelstein Bert; Lengauer Christoph; Nowak Martin A
Can chromosomal instability initiate tumorigenesis?
Seminars in cancer biology 2005;15(1):43-9.
2005: Bettegowda Chetan; Foss Catherine A; Cheong Ian; Wang Yuchuan; Diaz Luis; Agrawal Nishant; Fox James; Dick James; Dang Long H; Zhou Shibin; Kinzler Kenneth W; Vogelstein Bert; Pomper Martin G
Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1145-50.
2004: Barber Thomas D; Vogelstein Bert; Kinzler Kenneth W; Velculescu Victor E
Somatic mutations of EGFR in colorectal cancers and glioblastomas.
The New England journal of medicine 2004;351(27):2883.
2004: Bentires-Alj Mohamed; Paez J Guillermo; David Frank S; Keilhack Heike; Halmos Balazs; Naoki Katsuhiko; Maris John M; Richardson Andrea; Bardelli Alberto; Sugarbaker David J; Richards William G; Du Jinyan; Girard Luc; Minna John D; Loh Mignon L; Fisher David E; Velculescu Victor E; Vogelstein Bert; Meyerson Matthew; Sellers William R; Neel Benjamin G
Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia.
Cancer research 2004;64(24):8816-20.
2004: Nanda Akash; Buckhaults Phillip; Seaman Steven; Agrawal Nishant; Boutin Paula; Shankara Srinivas; Nacht Mariana; Teicher Beverly; Stampfl Jason; Singh Sujay; Vogelstein Bert; Kinzler Kenneth W; St Croix Brad
Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R.
Cancer research 2004;64(23):8507-11.
2004: Kohli Manu; Yu Jian; Seaman Craig; Bardelli Alberto; Kinzler Kenneth W; Vogelstein Bert; Lengauer Christoph; Zhang Lin
SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(48):16897-902.
2004: Agrawal Nishant; Bettegowda Chetan; Cheong Ian; Geschwind Jean-Francois; Drake Charles G; Hipkiss Edward L; Tatsumi Mitsuaki; Dang Long H; Diaz Luis A; Pomper Martin; Abusedera Mohammad; Wahl Richard L; Kinzler Kenneth W; Zhou Shibin; Huso David L; Vogelstein Bert
Bacteriolytic therapy can generate a potent immune response against experimental tumors.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(42):15172-7.
2004: Vogelstein Bert; Kinzler Kenneth W
Cancer genes and the pathways they control.
Nature medicine 2004;10(8):789-99.
2004: Gurulingappa Hallur; Buckhalts Phillip; Kinzler Kenneth W; Vogelstein Bert; Khan Saeed R
Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase.
Bioorganic & medicinal chemistry letters 2004;14(13):3531-3.
2004: Cummins Jordan M; Vogelstein Bert
HAUSP is required for p53 destabilization.
Cell cycle (Georgetown, Tex.) 2004;3(6):689-92.
2004: Wang Zhenghe; Shen Dong; Parsons D Williams; Bardelli Alberto; Sager Jason; Szabo Steve; Ptak Janine; Silliman Natalie; Peters Brock A; van der Heijden Michiel S; Parmigiani Giovanni; Yan Hai; Wang Tian-Li; Riggins Greg; Powell Steven M; Willson James K V; Markowitz Sanford; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
Mutational analysis of the tyrosine phosphatome in colorectal cancers.
Science (New York, N.Y.) 2004;304(5674):1164-6.
2004: Cummins Jordan M; Kohli Manu; Rago Carlo; Kinzler Kenneth W; Vogelstein Bert; Bunz Fred
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells.
Cancer research 2004;64(9):3006-8.
2004: Wang Zhenghe; Cummins Jordan M; Shen Dong; Cahill Daniel P; Jallepalli Prasad V; Wang Tian-Li; Parsons D Williams; Traverso Giovanni; Awad Mark; Silliman Natalie; Ptak Janine; Szabo Steve; Willson James K V; Markowitz Sanford D; Goldberg Michael L; Karess Roger; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E; Lengauer Christoph
Three classes of genes mutated in colorectal cancers with chromosomal instability.
Cancer research 2004;64(9):2998-3001.
2004: Koopmann Jens; Buckhaults Phillip; Brown David A; Zahurak Marianna L; Sato Norihiro; Fukushima Noriyoshi; Sokoll Lori J; Chan Daniel W; Yeo Charles J; Hruban Ralph H; Breit Samuel N; Kinzler Kenneth W; Vogelstein Bert; Goggins Michael
Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2386-92.
2004: Cummins Jordan M; Rago Carlo; Kohli Manu; Kinzler Kenneth W; Lengauer Christoph; Vogelstein Bert
Tumour suppression: disruption of HAUSP gene stabilizes p53.
Nature 2004;428(6982):1 p following 486.
2004: Samuels Yardena; Wang Zhenghe; Bardelli Alberto; Silliman Natalie; Ptak Janine; Szabo Steve; Yan Hai; Gazdar Adi; Powell Steven M; Riggins Gregory J; Willson James K V; Markowitz Sanford; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
High frequency of mutations of the PIK3CA gene in human cancers.
Science (New York, N.Y.) 2004;304(5670):554.
2004: Rajagopalan Harith; Jallepalli Prasad V; Rago Carlo; Velculescu Victor E; Kinzler Kenneth W; Vogelstein Bert; Lengauer Christoph
Inactivation of hCDC4 can cause chromosomal instability.
Nature 2004;428(6978):77-81.
2004: Wang Tian-Li; Diaz Luis A; Romans Katharine; Bardelli Alberto; Saha Saurabh; Galizia Gennaro; Choti Michael; Donehower Ross; Parmigiani Giovanni; Shih Ie-Ming; Iacobuzio-Donahue Christine; Kinzler Kenneth W; Vogelstein Bert; Lengauer Christoph; Velculescu Victor E
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3089-94.
2004: Dang Long H; Bettegowda Chetan; Agrawal Nishant; Cheong Ian; Huso David; Frost Philip; Loganzo Frank; Greenberger Lee; Barkoczy Jozsef; Pettit George R; Smith Amos B; Gurulingappa Hallur; Khan Saeed; Parmigiani Giovanni; Kinzler Kenneth W; Zhou Shibin; Vogelstein Bert
Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agents.
Cancer biology & therapy 2004;3(3):326-37.
2004: Nanda Akash; Carson-Walter Eleanor B; Seaman Steven; Barber Thomas D; Stampfl Jason; Singh Sujay; Vogelstein Bert; Kinzler Kenneth W; St Croix Brad
TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI).
Cancer research 2004;64(3):817-20.
2004: Kohli Manu; Rago Carlo; Lengauer Christoph; Kinzler Kenneth W; Vogelstein Bert
Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses.
Nucleic acids research 2004;32(1):e3.
2003: Traverso Giovanni; Bettegowda Chetan; Kraus Jürgen; Speicher Michael R; Kinzler Kenneth W; Vogelstein Bert; Lengauer Christoph
Hyper-recombination and genetic instability in BLM-deficient epithelial cells.
Cancer research 2003;63(24):8578-81.
2003: Bettegowda Chetan; Dang Long H; Abrams Ross; Huso David L; Dillehay Larry; Cheong Ian; Agrawal Nishant; Borzillary Scott; McCaffery J Michael; Watson E Latice; Lin Kuo-Shyan; Bunz Fred; Baidoo Kwamena; Pomper Martin G; Kinzler Kenneth W; Vogelstein Bert; Zhou Shibin
Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15083-8.
2003: Baker Suzanne J; Kinzler Kenneth W; Vogelstein Bert
Knudson's hypothesis and the TP53 revolution.
Genes, chromosomes & cancer 2003;38(4):329.
2003: Bardelli Alberto; Saha Saurabh; Sager Jason A; Romans Kathy E; Xin Baozhong; Markowitz Sanford D; Lengauer Christoph; Velculescu Victor E; Kinzler Kenneth W; Vogelstein Bert
PRL-3 expression in metastatic cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5607-15.
2003: Wang Zhenghe; Vogelstein Bert; Kinzler Kenneth W
Phosphorylation of beta-catenin at S33, S37, or T41 can occur in the absence of phosphorylation at T45 in colon cancer cells.
Cancer research 2003;63(17):5234-5.
2003: Rajagopalan Harith; Nowak Martin A; Vogelstein Bert; Lengauer Christoph
The significance of unstable chromosomes in colorectal cancer.
Nature reviews. Cancer 2003;3(9):695-701.
2003: Traverso Giovanni; Diehl Frank; Hurst Robin; Shuber Anthony; Whitney Duncan; Johnson Constance; Levin Bernard; Kinzler Kenneth W; Vogelstein Bert
Multicolor in vitro translation.
Nature biotechnology 2003;21(9):1093-7.
2003: Dressman Devin; Yan Hai; Traverso Giovanni; Kinzler Kenneth W; Vogelstein Bert
Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8817-22.
2003: Brown David A; Ward Robyn L; Buckhaults Philip; Liu Tao; Romans Katharine E; Hawkins Nicholas J; Bauskin Asne R; Kinzler Kenneth W; Vogelstein Bert; Breit Samuel N
MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2642-50.
2003: Jallepalli Prasad V; Lengauer Christoph; Vogelstein Bert; Bunz Fred
The Chk2 tumor suppressor is not required for p53 responses in human cancer cells.
The Journal of biological chemistry 2003;278(23):20475-9.
2003: Bardelli Alberto; Parsons D Williams; Silliman Natalie; Ptak Janine; Szabo Steve; Saha Saurabh; Markowitz Sanford; Willson James K V; Parmigiani Giovanni; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
Mutational analysis of the tyrosine kinome in colorectal cancers.
Science (New York, N.Y.) 2003;300(5621):949.
2003: Hempen Paula M; Zhang Lin; Bansal Ravi K; Iacobuzio-Donahue Christine A; Murphy Kathleen M; Maitra Anirban; Vogelstein Bert; Whitehead Robert H; Markowitz Sanford D; Willson James K V; Yeo Charles J; Hruban Ralph H; Kern Scott E
Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.
Cancer research 2003;63(5):994-9.
2003: Yu Jian; Wang Zhenghe; Kinzler Kenneth W; Vogelstein Bert; Zhang Lin
PUMA mediates the apoptotic response to p53 in colorectal cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1931-6.
2003: Bachman Kurtis E; Park Ben Ho; Rhee Ina; Rajagopalan Harith; Herman James G; Baylin Stephen B; Kinzler Kenneth W; Vogelstein Bert
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.
Cancer cell 2003;3(1):89-95.
2002: Wang Tian-Li; Maierhofer Christine; Speicher Michael R; Lengauer Christoph; Vogelstein Bert; Kinzler Kenneth W; Velculescu Victor E
Digital karyotyping.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16156-61.
2002: Nowak Martin A; Komarova Natalia L; Sengupta Anirvan; Jallepalli Prasad V; Shih Ie-Ming; Vogelstein Bert; Lengauer Christoph
The role of chromosomal instability in tumor initiation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16226-31.
2002: Komarova Natalia L; Lengauer Christoph; Vogelstein Bert; Nowak Martin A
Dynamics of genetic instability in sporadic and familial colorectal cancer.
Cancer biology & therapy 2002;1(6):685-92.
2002: Sayed M G; Ahmed A F; Ringold J R; Anderson M E; Bair J L; Mitros F A; Lynch H T; Tinley S T; Petersen G M; Giardiello F M; Vogelstein B; Howe J R
Germline SMAD4 or BMPR1A mutations and phenotype of juvenile polyposis.
Annals of surgical oncology 2002;9(9):901-6.
2002: Rajagopalan Harith; Bardelli Alberto; Lengauer Christoph; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status.
Nature 2002;418(6901):934.
2002: Yan Hai; Yuan Weishi; Velculescu Victor E; Vogelstein Bert; Kinzler Kenneth W
Allelic variation in human gene expression.
Science (New York, N.Y.) 2002;297(5584):1143.
2002: Nakagawa Hidewaki; Yan Hai; Lockman Janet; Hampel Heather; Kinzler Kenneth W; Vogelstein Bert; De La Chapelle Albert
Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements.
Cancer research 2002;62(16):4579-82.
2002: Chan Timothy A; Wang Zhenghe; Dang Long H; Vogelstein Bert; Kinzler Kenneth W
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8265-70.
2002: Saha Saurabh; Sparks Andrew B; Rago Carlo; Akmaev Viatcheslav; Wang Clarence J; Vogelstein Bert; Kinzler Kenneth W; Velculescu Victor E
Using the transcriptome to annotate the genome.
Nature biotechnology 2002;20(5):508-12.
2002: Rhee Ina; Bachman Kurtis E; Park Ben Ho; Jair Kam-Wing; Yen Ray-Whay Chiu; Schuebel Kornel E; Cui Hengmi; Feinberg Andrew P; Lengauer Christoph; Kinzler Kenneth W; Baylin Stephen B; Vogelstein Bert
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.
Nature 2002;416(6880):552-6.
2002: Zawel Leigh; Yu Jian; Torrance Christopher J; Markowitz Sanford; Kinzler Kenneth W; Vogelstein Bert; Zhou Shibin
DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2848-53.
2002: Wang Tian-Li; Rago Carlo; Silliman Natalie; Ptak Janine; Markowitz Sanford; Willson James K V; Parmigiani Giovanni; Kinzler Kenneth W; Vogelstein Bert; Velculescu Victor E
Prevalence of somatic alterations in the colorectal cancer cell genome.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3076-80.
2002: Bunz Fred; Fauth Christine; Speicher Michael R; Dutriaux Annie; Sedivy John M; Kinzler Kenneth W; Vogelstein Bert; Lengauer Christoph
Targeted inactivation of p53 in human cells does not result in aneuploidy.
Cancer research 2002;62(4):1129-33.
2002: Vogelstein Bert; Alberts Bruce; Shine Kenneth
Genetics. Please don't call it cloning!
Science (New York, N.Y.) 2002;295(5558):1237.
2002: Traverso Giovanni; Shuber Anthony; Olsson Louise; Levin Bernard; Johnson Constance; Hamilton Stanley R; Boynton Kevin; Kinzler Kenneth W; Vogelstein Bert
Detection of proximal colorectal cancers through analysis of faecal DNA.
Lancet 2002;359(9304):403-4.
2002: Traverso Giovanni; Shuber Anthony; Levin Bernard; Johnson Constance; Olsson Louise; Schoetz David J; Hamilton Stanley R; Boynton Kevin; Kinzler Kenneth W; Vogelstein Bert
Detection of APC mutations in fecal DNA from patients with colorectal tumors.
The New England journal of medicine 2002;346(5):311-20.
2002: Zhou Wei; Goodman Steven N; Galizia Gennaro; Lieto Eva; Ferraraccio Francesca; Pignatelli Carlo; Purdie Colin A; Piris Juan; Morris Robert; Harrison David J; Paty Philip B; Culliford Al; Romans Katharine E; Montgomery Elizabeth A; Choti Michael A; Kinzler Kenneth W; Vogelstein Bert
Counting alleles to predict recurrence of early-stage colorectal cancers.
Lancet 2002;359(9302):219-25.
2002: Yan Hai; Dobbie Zuzana; Gruber Stephen B; Markowitz Sanford; Romans Kathy; Giardiello Francis M; Kinzler Kenneth W; Vogelstein Bert
Small changes in expression affect predisposition to tumorigenesis.
Nature genetics 2002;30(1):25-6.
2001: Dang L H; Bettegowda C; Huso D L; Kinzler K W; Vogelstein B
Combination bacteriolytic therapy for the treatment of experimental tumors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15155-60.
2001: Liu T; Yan H; Kuismanen S; Percesepe A; Bisgaard M L; Pedroni M; Benatti P; Kinzler K W; Vogelstein B; Ponz de Leon M; Peltomäki P; Lindblom A
The role of hPMS1 and hPMS2 in predisposing to colorectal cancer.
Cancer research 2001;61(21):7798-802.
2001: Marra G; D'Atri S; Yan H; Perrera C; Cannavo' E; Vogelstein B; Jiricny J
Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes.
Cancer research 2001;61(21):7719-21.
2001: Saha S; Bardelli A; Buckhaults P; Velculescu V E; Rago C; St Croix B; Romans K E; Choti M A; Lengauer C; Kinzler K W; Vogelstein B
A phosphatase associated with metastasis of colorectal cancer.
Science (New York, N.Y.) 2001;294(5545):1343-6.
2001: Hwang P M; Bunz F; Yu J; Rago C; Chan T A; Murphy M P; Kelso G F; Smith R A; Kinzler K W; Vogelstein B
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells.
Nature medicine 2001;7(10):1111-7.
2001: Buckhaults P; Rago C; St Croix B; Romans K E; Saha S; Zhang L; Vogelstein B; Kinzler K W
Secreted and cell surface genes expressed in benign and malignant colorectal tumors.
Cancer research 2001;61(19):6996-7001.
2001: Torrance C J; Agrawal V; Vogelstein B; Kinzler K W
Use of isogenic human cancer cells for high-throughput screening and drug discovery.
Nature biotechnology 2001;19(10):940-5.
2001: Carson-Walter E B; Watkins D N; Nanda A; Vogelstein B; Kinzler K W; St Croix B
Cell surface tumor endothelial markers are conserved in mice and humans.
Cancer research 2001;61(18):6649-55.
2001: Vogelstein B; Kinzler K W
Achilles' heel of cancer?
Nature 2001;412(6850):865-6.
2001: Dong S M; Traverso G; Johnson C; Geng L; Favis R; Boynton K; Hibi K; Goodman S N; D'Allessio M; Paty P; Hamilton S R; Sidransky D; Barany F; Levin B; Shuber A; Kinzler K W; Vogelstein B; Jen J
Detecting colorectal cancer in stool with the use of multiple genetic targets.
Journal of the National Cancer Institute 2001;93(11):858-65.
2001: Howe J R; Bair J L; Sayed M G; Anderson M E; Mitros F A; Petersen G M; Velculescu V E; Traverso G; Vogelstein B
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.
Nature genetics 2001;28(2):184-7.
2001: Jallepalli P V; Waizenegger I C; Bunz F; Langer S; Speicher M R; Peters J M; Kinzler K W; Vogelstein B; Lengauer C
Securin is required for chromosomal stability in human cells.
Cell 2001;105(4):445-57.
2001: Zhang L; Yu J; Willson J K; Markowitz S D; Kinzler K W; Vogelstein B
Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers.
Cancer research 2001;61(9):3801-5.
2001: Bardelli A; Cahill D P; Lederer G; Speicher M R; Kinzler K W; Vogelstein B; Lengauer C
Carcinogen-specific induction of genetic instability.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5770-5.
2001: Yu J; Zhang L; Hwang P M; Kinzler K W; Vogelstein B
PUMA induces the rapid apoptosis of colorectal cancer cells.
Molecular cell 2001;7(3):673-82.
2001: Sparks A B; Peterson S N; Bell C; Loftus B J; Hocking L; Cahill D P; Frassica F J; Streeten E A; Levine M A; Fraser C M; Adams M D; Broder S; Venter J C; Kinzler K W; Vogelstein B; Ralston S H
Mutation screening of the TNFRSF11A gene encoding receptor activator of NF kappa B (RANK) in familial and sporadic Paget's disease of bone and osteosarcoma.
Calcified tissue international 2001;68(3):151-5.
2001: Thiagalingam S; Laken S; Willson J K; Markowitz S D; Kinzler K W; Vogelstein B; Lengauer C
Mechanisms underlying losses of heterozygosity in human colorectal cancers.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2698-702.
2001: Shih I M; Wang T L; Traverso G; Romans K; Hamilton S R; Ben-Sasson S; Kinzler K W; Vogelstein B
Top-down morphogenesis of colorectal tumors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2640-5.
2001: Park B H; Vogelstein B; Kinzler K W
Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2598-603.
2001: Shih I M; Zhou W; Goodman S N; Lengauer C; Kinzler K W; Vogelstein B
Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis.
Cancer research 2001;61(3):818-22.
2001: Jackson P E; Qian G S; Friesen M D; Zhu Y R; Lu P; Wang J B; Wu Y; Kensler T W; Vogelstein B; Groopman J D
Specific p53 mutations detected in plasma and tumors of hepatocellular carcinoma patients by electrospray ionization mass spectrometry.
Cancer research 2001;61(1):33-5.
2001: Fink S P; Swinler S E; Lutterbaugh J D; Massagué J; Thiagalingam S; Kinzler K W; Vogelstein B; Willson J K; Markowitz S
Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line.
Cancer research 2001;61(1):256-60.
2001: Zhou W; Galizia G; Lieto E; Goodman S N; Romans K E; Kinzler K W; Vogelstein B; Choti M A; Montgomery E A
Counting alleles reveals a connection between chromosome 18q loss and vascular invasion.
Nature biotechnology 2001;19(1):78-81.
2000: Vogelstein B; Lane D; Levine A J
Surfing the p53 network.
Nature 2000;408(6810):307-10.
2000: Zhang L; Yu J; Park B H; Kinzler K W; Vogelstein B
Role of BAX in the apoptotic response to anticancer agents.
Science (New York, N.Y.) 2000;290(5493):989-92.
2000: Velculescu V E; Vogelstein B; Kinzler K W
Analysing uncharted transcriptomes with SAGE.
Trends in genetics : TIG 2000;16(10):423-5.
2000: Yan H; Kinzler K W; Vogelstein B
Tech.sight. Genetic testing--present and future.
Science (New York, N.Y.) 2000;289(5486):1890-2.
2000: Torrance C J; Jackson P E; Montgomery E; Kinzler K W; Vogelstein B; Wissner A; Nunes M; Frost P; Discafani C M
Combinatorial chemoprevention of intestinal neoplasia.
Nature medicine 2000;6(9):1024-8.
2000: St Croix B; Rago C; Velculescu V; Traverso G; Romans K E; Montgomery E; Lal A; Riggins G J; Lengauer C; Vogelstein B; Kinzler K W
Genes expressed in human tumor endothelium.
Science (New York, N.Y.) 2000;289(5482):1197-202.
2000: Flatt P M; Polyak K; Tang L J; Scatena C D; Westfall M D; Rubinstein L A; Yu J; Kinzler K W; Vogelstein B; Hill D E; Pietenpol J A
p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest.
Cancer letters 2000;156(1):63-72.
2000: Chan T A; Hwang P M; Hermeking H; Kinzler K W; Vogelstein B
Cooperative effects of genes controlling the G(2)/M checkpoint.
Genes & development 2000;14(13):1584-8.
2000: Shih I M; Torrance C; Sokoll L J; Chan D W; Kinzler K W; Vogelstein B
Assessing tumors in living animals through measurement of urinary beta-human chorionic gonadotropin.
Nature medicine 2000;6(6):711-4.
2000: Rhee I; Jair K W; Yen R W; Lengauer C; Herman J G; Kinzler K W; Vogelstein B; Baylin S B; Schuebel K E
CpG methylation is maintained in human cancer cells lacking DNMT1.
Nature 2000;404(6781):1003-7.
2000: Shih I M; Yu J; He T C; Vogelstein B; Kinzler K W
The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression.
Cancer research 2000;60(6):1671-6.
2000: Yan H; Papadopoulos N; Marra G; Perrera C; Jiricny J; Boland C R; Lynch H T; Chadwick R B; de la Chapelle A; Berg K; Eshleman J R; Yuan W; Markowitz S; Laken S J; Lengauer C; Kinzler K W; Vogelstein B
Conversion of diploidy to haploidy.
Nature 2000;403(6771):723-4.
2000: Hermeking H; Rago C; Schuhmacher M; Li Q; Barrett J F; Obaya A J; O'Connell B C; Mateyak M K; Tam W; Kohlhuber F; Dang C V; Sedivy J M; Eick D; Vogelstein B; Kinzler K W
Identification of CDK4 as a target of c-MYC.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2229-34.
1999: Cahill D P; Kinzler K W; Vogelstein B; Lengauer C
Genetic instability and darwinian selection in tumours.
Trends in cell biology 1999;9(12):M57-60.
1999: Yu J; Zhang L; Hwang P M; Rago C; Kinzler K W; Vogelstein B
Identification and classification of p53-regulated genes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14517-22.
1999: Lal A; Lash A E; Altschul S F; Velculescu V; Zhang L; McLendon R E; Marra M A; Prange C; Morin P J; Polyak K; Papadopoulos N; Vogelstein B; Kinzler K W; Strausberg R L; Riggins G J
A public database for gene expression in human cancers.
Cancer research 1999;59(21):5403-7.
1999: He T C; Chan T A; Vogelstein B; Kinzler K W
PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs.
Cell 1999;99(3):335-45.
1999: Chan T A; Hermeking H; Lengauer C; Kinzler K W; Vogelstein B
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage.
Nature 1999;401(6753):616-20.
1999: Zhou S; Kinzler K W; Vogelstein B
Going mad with Smads.
The New England journal of medicine 1999;341(15):1144-6.
1999: da Costa L T; He T C; Yu J; Sparks A B; Morin P J; Polyak K; Laken S; Vogelstein B; Kinzler K W
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
Oncogene 1999;18(35):5010-4.
1999: Vogelstein B; Kinzler K W
Digital PCR.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9236-41.
1999: Bunz F; Hwang P M; Torrance C; Waldman T; Zhang Y; Dillehay L; Williams J; Lengauer C; Kinzler K W; Vogelstein B
Disruption of p53 in human cancer cells alters the responses to therapeutic agents.
The Journal of clinical investigation 1999;104(3):263-9.
1999: Cahill D P; da Costa L T; Carson-Walter E B; Kinzler K W; Vogelstein B; Lengauer C
Characterization of MAD2B and other mitotic spindle checkpoint genes.
Genomics 1999;58(2):181-7.
1999: Laken S J; Papadopoulos N; Petersen G M; Gruber S B; Hamilton S R; Giardiello F M; Brensinger J D; Vogelstein B; Kinzler K W
Analysis of masked mutations in familial adenomatous polyposis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2322-6.
1999: Grady W M; Myeroff L L; Swinler S E; Rajput A; Thiagalingam S; Lutterbaugh J D; Neumann A; Brattain M G; Chang J; Kim S J; Kinzler K W; Vogelstein B; Willson J K; Markowitz S
Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers.
Cancer research 1999;59(2):320-4.
1999: Vogelstein B
Genetic testings for cancer: the surgeon's critical role. Familial colon cancer.
Journal of the American College of Surgeons 1999;188(1):74-9.
1999: Gruber S B; Petersen G M; Kinzler K W; Vogelstein B
Cancer, crash sites, and the new genetics of neoplasia.
Gastroenterology 1999;116(1):210-2.
1998: Lengauer C; Kinzler K W; Vogelstein B
Genetic instabilities in human cancers.
Nature 1998;396(6712):643-9.
1998: Laken S J; Jackson P E; Kinzler K W; Vogelstein B; Strickland P T; Groopman J D; Friesen M D
Genotyping by mass spectrometric analysis of short DNA fragments.
Nature biotechnology 1998;16(13):1352-6.
1998: Gruber S B; Entius M M; Petersen G M; Laken S J; Longo P A; Boyer R; Levin A M; Mujumdar U J; Trent J M; Kinzler K W; Vogelstein B; Hamilton S R; Polymeropoulos M H; Offerhaus G J; Giardiello F M
Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome.
Cancer research 1998;58(23):5267-70.
1998: Bunz F; Dutriaux A; Lengauer C; Waldman T; Zhou S; Brown J P; Sedivy J M; Kinzler K W; Vogelstein B
Requirement for p53 and p21 to sustain G2 arrest after DNA damage.
Science (New York, N.Y.) 1998;282(5393):1497-501.
1998: Polyak K; Li Y; Zhu H; Lengauer C; Willson J K; Markowitz S D; Trush M A; Kinzler K W; Vogelstein B
Somatic mutations of the mitochondrial genome in human colorectal tumours.
Nature genetics 1998;20(3):291-3.
1998: Fujiwara T; Stolker J M; Watanabe T; Rashid A; Longo P; Eshleman J R; Booker S; Lynch H T; Jass J R; Green J S; Kim H; Jen J; Vogelstein B; Hamilton S R
Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences.
The American journal of pathology 1998;153(4):1063-78.
1998: He T C; Sparks A B; Rago C; Hermeking H; Zawel L; da Costa L T; Morin P J; Vogelstein B; Kinzler K W
Identification of c-MYC as a target of the APC pathway.
Science (New York, N.Y.) 1998;281(5382):1509-12.
1998: Zhou S; Zawel L; Lengauer C; Kinzler K W; Vogelstein B
Characterization of human FAST-1, a TGF beta and activin signal transducer.
Molecular cell 1998;2(1):121-7.
1998: Herman J G; Umar A; Polyak K; Graff J R; Ahuja N; Issa J P; Markowitz S; Willson J K; Hamilton S R; Kinzler K W; Kane M F; Kolodner R D; Vogelstein B; Kunkel T A; Baylin S B
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6870-5.
1998: Kinzler K W; Vogelstein B
Landscaping the cancer terrain.
Science (New York, N.Y.) 1998;280(5366):1036-7.
1998: Zawel L; Dai J L; Buckhaults P; Zhou S; Kinzler K W; Vogelstein B; Kern S E
Human Smad3 and Smad4 are sequence-specific transcription activators.
Molecular cell 1998;1(4):611-7.
1998: Cahill D P; Lengauer C; Yu J; Riggins G J; Willson J K; Markowitz S D; Kinzler K W; Vogelstein B
Mutations of mitotic checkpoint genes in human cancers.
Nature 1998;392(6673):300-3.
1998: Sparks A B; Morin P J; Vogelstein B; Kinzler K W
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.
Cancer research 1998;58(6):1130-4.
1998: Nicolaides N C; Littman S J; Modrich P; Kinzler K W; Vogelstein B
A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype.
Molecular and cellular biology 1998;18(3):1635-41.
1998: He T C; Zhou S; da Costa L T; Yu J; Kinzler K W; Vogelstein B
A simplified system for generating recombinant adenoviruses.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2509-14.
1998: Zhou S; Buckhaults P; Zawel L; Bunz F; Riggins G; Dai J L; Kern S E; Kinzler K W; Vogelstein B
Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2412-6.
1998: Zhou W; Sokoll L J; Bruzek D J; Zhang L; Velculescu V E; Goldin S B; Hruban R H; Kern S E; Hamilton S R; Chan D W; Vogelstein B; Kinzler K W
Identifying markers for pancreatic cancer by gene expression analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(2):109-12.
1998: Chan T A; Morin P J; Vogelstein B; Kinzler K W
Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(2):681-6.
1997: Hermeking H; Lengauer C; Polyak K; He T C; Zhang L; Thiagalingam S; Kinzler K W; Vogelstein B
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression.
Molecular cell 1997;1(1):3-11.
1997: Polyak K; Xia Y; Zweier J L; Kinzler K W; Vogelstein B
A model for p53-induced apoptosis.
Nature 1997;389(6648):300-5.
1997: Waldman T; Zhang Y; Dillehay L; Yu J; Kinzler K; Vogelstein B; Williams J
Cell-cycle arrest versus cell death in cancer therapy.
Nature medicine 1997;3(9):1034-6.
1997: Laken S J; Petersen G M; Gruber S B; Oddoux C; Ostrer H; Giardiello F M; Hamilton S R; Hampel H; Markowitz A; Klimstra D; Jhanwar S; Winawer S; Offit K; Luce M C; Kinzler K W; Vogelstein B
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.
Nature genetics 1997;17(1):79-83.
1997: Riggins G J; Kinzler K W; Vogelstein B; Thiagalingam S
Frequency of Smad gene mutations in human cancers.
Cancer research 1997;57(13):2578-80.
1997: Zhang L; Zhou W; Velculescu V E; Kern S E; Hruban R H; Hamilton S R; Vogelstein B; Kinzler K W
Gene expression profiles in normal and cancer cells.
Science (New York, N.Y.) 1997;276(5316):1268-72.
1997: Polyak K; Wu T T; Hamilton S R; Kinzler K W; Vogelstein B
Less death in the dying.
Cell death and differentiation 1997;4(3):242-6.
1997: Giardiello F M; Petersen G M; Piantadosi S; Gruber S B; Traboulsi E I; Offerhaus G J; Muro K; Krush A J; Booker S V; Luce M C; Laken S J; Kinzler K W; Vogelstein B; Hamilton S R
APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis.
Gut 1997;40(4):521-5.
1997: Kinzler K W; Vogelstein B
Cancer-susceptibility genes. Gatekeepers and caretakers.
Nature 1997;386(6627):761, 763.
1997: Lengauer C; Kinzler K W; Vogelstein B
Genetic instability in colorectal cancers.
Nature 1997;386(6625):623-7.
1997: Lengauer C; Kinzler K W; Vogelstein B
DNA methylation and genetic instability in colorectal cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2545-50.
1997: Morin P J; Sparks A B; Korinek V; Barker N; Clevers H; Vogelstein B; Kinzler K W
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.
Science (New York, N.Y.) 1997;275(5307):1787-90.
1997: Korinek V; Barker N; Morin P J; van Wichen D; de Weger R; Kinzler K W; Vogelstein B; Clevers H
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.
Science (New York, N.Y.) 1997;275(5307):1784-7.
1997: Velculescu V E; Zhang L; Zhou W; Vogelstein J; Basrai M A; Bassett D E; Hieter P; Vogelstein B; Kinzler K W
Characterization of the yeast transcriptome.
Cell 1997;88(2):243-51.
1997: Dunlop M G; Farrington S M; Carothers A D; Wyllie A H; Sharp L; Burn J; Liu B; Kinzler K W; Vogelstein B
Cancer risk associated with germline DNA mismatch repair gene mutations.
Human molecular genetics 1997;6(1):105-10.
1996: Dowell S P; McGoogan E; Picksley S M; el-Deiry W S; Vogelstein B; Hall P A
Expression of p21waf1/Cip1, MDM2 and p53 in vivo: analysis of cytological preparations.
Cytopathology : official journal of the British Society for Clinical Cytology 1996;7(5):340-51.
1996: Derynck R; Gelbart W M; Harland R M; Heldin C H; Kern S E; Massagué J; Melton D A; Mlodzik M; Padgett R W; Roberts A B; Smith J; Thomsen G H; Vogelstein B; Wang X F
Nomenclature: vertebrate mediators of TGFbeta family signals.
Cell 1996;87(2):173.
1996: Kinzler K W; Vogelstein B
Lessons from hereditary colorectal cancer.
Cell 1996;87(2):159-70.
1996: Huang J; Papadopoulos N; McKinley A J; Farrington S M; Curtis L J; Wyllie A H; Zheng S; Willson J K; Markowitz S D; Morin P; Kinzler K W; Vogelstein B; Dunlop M G
APC mutations in colorectal tumors with mismatch repair deficiency.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9049-54.
1996: Beazer-Barclay Y; Levy D B; Moser A R; Dove W F; Hamilton S R; Vogelstein B; Kinzler K W
Sulindac suppresses tumorigenesis in the Min mouse.
Carcinogenesis 1996;17(8):1757-60.
1996: Polyak K; Waldman T; He T C; Kinzler K W; Vogelstein B
Genetic determinants of p53-induced apoptosis and growth arrest.
Genes & development 1996;10(15):1945-52.
1996: Kinzler K W; Vogelstein B
Breast cancer. What's mice got to do with it?
Nature 1996;382(6593):672.
1996: Pietenpol J A; Lengauer C; Jordan J; Kinzler K W; Vogelstein B
Mammalian cells resistant to tumor suppressor genes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8390-4.
1996: Polyak K; Hamilton S R; Vogelstein B; Kinzler K W
Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia.
The American journal of pathology 1996;149(2):381-7.
1996: Morin P J; Vogelstein B; Kinzler K W
Apoptosis and APC in colorectal tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7950-4.
1996: Thiagalingam S; Lisitsyn N A; Hamaguchi M; Wigler M H; Willson J K; Markowitz S D; Leach F S; Kinzler K W; Vogelstein B
Evaluation of the FHIT gene in colorectal cancers.
Cancer research 1996;56(13):2936-9.
1996: Riggins G J; Thiagalingam S; Rozenblum E; Weinstein C L; Kern S E; Hamilton S R; Willson J K; Markowitz S D; Kinzler K W; Vogelstein B
Mad-related genes in the human.
Nature genetics 1996;13(3):347-9.
1996: Thiagalingam S; Lengauer C; Leach F S; Schutte M; Hahn S A; Overhauser J; Willson J K; Markowitz S; Hamilton S R; Kern S E; Kinzler K W; Vogelstein B
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers.
Nature genetics 1996;13(3):343-6.
1996: Waldman T; Lengauer C; Kinzler K W; Vogelstein B
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21.
Nature 1996;381(6584):713-6.
1996: Da Costa L T; Jen J; He T C; Chan T A; Kinzler K W; Vogelstein B
Converting cancer genes into killer genes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4192-6.
1996: Nicolaides N C; Palombo F; Kinzler K W; Vogelstein B; Jiricny J
Molecular cloning of the N-terminus of GTBP.
Genomics 1996;31(3):395-7.
1996: Liu B; Parsons R; Papadopoulos N; Nicolaides N C; Lynch H T; Watson P; Jass J R; Dunlop M; Wyllie A; Peltomäki P; de la Chapelle A; Hamilton S R; Vogelstein B; Kinzler K W
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients.
Nature medicine 1996;2(2):169-74.
1996: Leach F S; Polyak K; Burrell M; Johnson K A; Hill D; Dunlop M G; Wyllie A H; Peltomaki P; de la Chapelle A; Hamilton S R; Kinzler K W; Vogelstein B
Expression of the human mismatch repair gene hMSH2 in normal and neoplastic tissues.
Cancer research 1996;56(2):235-40.
1996: Kinzler K W; Vogelstein B
Life (and death) in a malignant tumour.
Nature 1996;379(6560):19-20.
1995: Parsons R; Myeroff L L; Liu B; Willson J K; Markowitz S D; Kinzler K W; Vogelstein B
Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer.
Cancer research 1995;55(23):5548-50.
1995: Nicolaides N C; Carter K C; Shell B K; Papadopoulos N; Vogelstein B; Kinzler K W
Genomic organization of the human PMS2 gene family.
Genomics 1995;30(2):195-206.
1995: Waldman T; Kinzler K W; Vogelstein B
p21 is necessary for the p53-mediated G1 arrest in human cancer cells.
Cancer research 1995;55(22):5187-90.
1995: Riggins G J; Markowitz S; Wilson J K; Vogelstein B; Kinzler K W
Absence of secretory phospholipase A2 gene alterations in human colorectal cancer.
Cancer research 1995;55(22):5184-6.
1995: Nyström-Lahti M; Kristo P; Nicolaides N C; Chang S Y; Aaltonen L A; Moisio A L; Järvinen H J; Mecklin J P; Kinzler K W; Vogelstein B
Founding mutations and Alu-mediated recombination in hereditary colon cancer.
Nature medicine 1995;1(11):1203-6.
1995: Velculescu V E; Zhang L; Vogelstein B; Kinzler K W
Serial analysis of gene expression.
Science (New York, N.Y.) 1995;270(5235):484-7.
1995: Nicolaides N C; Kinzler K W; Vogelstein B
Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene.
Genomics 1995;29(2):329-34.
1995: Papadopoulos N; Leach F S; Kinzler K W; Vogelstein B
Monoallelic mutation analysis (MAMA) for identifying germline mutations.
Nature genetics 1995;11(1):99-102.
1995: Sato Y; Suto Y; Pietenpol J; Golub T R; Gilliland D G; Davis E M; Le Beau M M; Roberts J M; Vogelstein B; Rowley J D
TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies.
Blood 1995;86(4):1525-33.
1995: Su L K; Burrell M; Hill D E; Gyuris J; Brent R; Wiltshire R; Trent J; Vogelstein B; Kinzler K W
APC binds to the novel protein EB1.
Cancer research 1995;55(14):2972-7.
1995: Markowitz S; Wang J; Myeroff L; Parsons R; Sun L; Lutterbaugh J; Fan R S; Zborowska E; Kinzler K W; Vogelstein B
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.
Science (New York, N.Y.) 1995;268(5215):1336-8.
1995: Thiagalingam S; Kinzler K W; Vogelstein B
PAK1, a gene that can regulate p53 activity in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):6062-6.
1995: Parsons R; Li G M; Longley M; Modrich P; Liu B; Berk T; Hamilton S R; Kinzler K W; Vogelstein B
Mismatch repair deficiency in phenotypically normal human cells.
Science (New York, N.Y.) 1995;268(5211):738-40.
1995: Macleod K F; Sherry N; Hannon G; Beach D; Tokino T; Kinzler K; Vogelstein B; Jacks T
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.
Genes & development 1995;9(8):935-44.
1995: Eshleman J R; Lang E Z; Bowerfind G K; Parsons R; Vogelstein B; Willson J K; Veigl M L; Sedwick W D; Markowitz S D
Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer.
Oncogene 1995;10(1):33-7.
1995: da Costa L T; Liu B; el-Deiry W; Hamilton S R; Kinzler K W; Vogelstein B; Markowitz S; Willson J K; de la Chapelle A; Downey K M
Polymerase delta variants in RER colorectal tumours.
Nature genetics 1995;9(1):10-1.
1995: Trent J M; Wiltshire R; Su L K; Nicolaides N C; Vogelstein B; Kinzler K W
The gene for the APC-binding protein beta-catenin (CTNNB1) maps to chromosome 3p22, a region frequently altered in human malignancies.
Cytogenetics and cell genetics 1995;71(4):343-4.
1994: Jen J; Harper J W; Bigner S H; Bigner D D; Papadopoulos N; Markowitz S; Willson J K; Kinzler K W; Vogelstein B
Deletion of p16 and p15 genes in brain tumors.
Cancer research 1994;54(24):6353-8.
1994: Shiohara M; el-Deiry W S; Wada M; Nakamaki T; Takeuchi S; Yang R; Chen D L; Vogelstein B; Koeffler H P
Absence of WAF1 mutations in a variety of human malignancies.
Blood 1994;84(11):3781-4.
1994: Levy D B; Smith K J; Beazer-Barclay Y; Hamilton S R; Vogelstein B; Kinzler K W
Inactivation of both APC alleles in human and mouse tumors.
Cancer research 1994;54(22):5953-8.
1994: Jen J; Powell S M; Papadopoulos N; Smith K J; Hamilton S R; Vogelstein B; Kinzler K W
Molecular determinants of dysplasia in colorectal lesions.
Cancer research 1994;54(21):5523-6.
1994: Leach F S; Nicolaides N C; Sistonen P; Yu J W; Kao F T; de la Chapelle A; Kinzler K W; Vogelstein B
Three dinucleotide repeat polymorphisms proximal to the D2S123 locus.
Human molecular genetics 1994;3(11):2082.
1994: Vogelstein B; Kinzler K W
Has the breast cancer gene been found?
Cell 1994;79(1):1-3.
1994: Ueba T; Nosaka T; Takahashi J A; Shibata F; Florkiewicz R Z; Vogelstein B; Oda Y; Kikuchi H; Hatanaka M
Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9009-13.
1994: Lynch H T; Drouhard T; Lanspa S; Smyrk T; Lynch P; Lynch J; Vogelstein B; Nyström-Lahti M; Sistonen P; Peltomäki P
Mutation of an mutL homologue in a Navajo family with hereditary nonpolyposis colorectal cancer.
Journal of the National Cancer Institute 1994;86(18):1417-9.
1994: Tokino T; Thiagalingam S; el-Deiry W S; Waldman T; Kinzler K W; Vogelstein B
p53 tagged sites from human genomic DNA.
Human molecular genetics 1994;3(9):1537-42.
1994: Kinzler K W; Vogelstein B
Cancer therapy meets p53.
The New England journal of medicine 1994;331(1):49-50.
1994: Pietenpol J A; Papadopoulos N; Markowitz S; Willson J K; Kinzler K W; Vogelstein B
Paradoxical inhibition of solid tumor cell growth by bcl2.
Cancer research 1994;54(14):3714-7.
1994: Smith K J; Levy D B; Maupin P; Pollard T D; Vogelstein B; Kinzler K W
Wild-type but not mutant APC associates with the microtubule cytoskeleton.
Cancer research 1994;54(14):3672-5.
1994: Kim H; Jen J; Vogelstein B; Hamilton S R
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences.
The American journal of pathology 1994;145(1):148-56.
1994: Vogelstein B; Kinzler K W
Tumour-suppressor genes. X-rays strike p53 again.
Nature 1994;370(6486):174-5.
1994: Jen J; Kim H; Piantadosi S; Liu Z F; Levitt R C; Sistonen P; Kinzler K W; Vogelstein B; Hamilton S R
Allelic loss of chromosome 18q and prognosis in colorectal cancer.
The New England journal of medicine 1994;331(4):213-21.
1994: Hedrick L; Cho K R; Fearon E R; Wu T C; Kinzler K W; Vogelstein B
The DCC gene product in cellular differentiation and colorectal tumorigenesis.
Genes & development 1994;8(10):1174-83.
1994: Chen C Y; Oliner J D; Zhan Q; Fornace A J; Vogelstein B; Kastan M B
Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2684-8.
1994: Pietenpol J A; Tokino T; Thiagalingam S; el-Deiry W S; Kinzler K W; Vogelstein B
Sequence-specific transcriptional activation is essential for growth suppression by p53.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):1998-2002.
1994: Pierceall W E; Cho K R; Getzenberg R H; Reale M A; Hedrick L; Vogelstein B; Fearon E R
NIH3T3 cells expressing the deleted in colorectal cancer tumor suppressor gene product stimulate neurite outgrowth in rat PC12 pheochromocytoma cells.
The Journal of cell biology 1994;124(6):1017-27.
1994: Cho K R; Oliner J D; Simons J W; Hedrick L; Fearon E R; Preisinger A C; Hedge P; Silverman G A; Vogelstein B
The DCC gene: structural analysis and mutations in colorectal carcinomas.
Genomics 1994;19(3):525-31.
1994: Baas I O; Mulder J W; Offerhaus G J; Vogelstein B; Hamilton S R
An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms.
The Journal of pathology 1994;172(1):5-12.
1994: Arthur R R; Grossman S A; Ronnett B M; Bigner S H; Vogelstein B; Shah K V
Lack of association of human polyomaviruses with human brain tumors.
Journal of neuro-oncology 1994;20(1):55-8.
1994: Lisitsyn N A; Leach F S; Vogelstein B; Wigler M H
Detection of genetic loss in tumors by representational difference analysis.
Cold Spring Harbor symposia on quantitative biology 1994;59():585-7.
1994: Vogelstein B; Kinzler K W
Colorectal cancer and the intersection between basic and clinical research.
Cold Spring Harbor symposia on quantitative biology 1994;59():517-21.
1993: Parsons R; Li G M; Longley M J; Fang W H; Papadopoulos N; Jen J; de la Chapelle A; Kinzler K W; Vogelstein B; Modrich P
Hypermutability and mismatch repair deficiency in RER+ tumor cells.
Cell 1993;75(6):1227-36.
1993: Su L K; Vogelstein B; Kinzler K W
Association of the APC tumor suppressor protein with catenins.
Science (New York, N.Y.) 1993;262(5140):1734-7.
1993: Powell S M; Petersen G M; Krush A J; Booker S; Jen J; Giardiello F M; Hamilton S R; Vogelstein B; Kinzler K W
Molecular diagnosis of familial adenomatous polyposis.
The New England journal of medicine 1993;329(27):1982-7.
1993: Oliner J D; Kinzler K W; Vogelstein B
In vivo cloning of PCR products in E. coli.
Nucleic acids research 1993;21(22):5192-7.
1993: el-Deiry W S; Tokino T; Velculescu V E; Levy D B; Parsons R; Trent J M; Lin D; Mercer W E; Kinzler K W; Vogelstein B
WAF1, a potential mediator of p53 tumor suppression.
Cell 1993;75(4):817-25.
1993: Pietenpol J A; Vogelstein B
Tumour suppressor genes. No room at the p53 inn.
Nature 1993;365(6441):17-8.
1993: Kinzler K W; Vogelstein B
Cancer. A gene for neurofibromatosis 2.
Nature 1993;363(6429):495-6.
1993: Su L K; Johnson K A; Smith K J; Hill D E; Vogelstein B; Kinzler K W
Association between wild type and mutant APC gene products.
Cancer research 1993;53(12):2728-31.
1993: Leach F S; Elledge S J; Sherr C J; Willson J K; Markowitz S; Kinzler K W; Vogelstein B
Amplification of cyclin genes in colorectal carcinomas.
Cancer research 1993;53(9):1986-9.
1993: Leach F S; Tokino T; Meltzer P; Burrell M; Oliner J D; Smith S; Hill D E; Sidransky D; Kinzler K W; Vogelstein B
p53 Mutation and MDM2 amplification in human soft tissue sarcomas.
Cancer research 1993;53(10 Suppl):2231-4.
1993: Vogelstein B; Kinzler K W
The multistep nature of cancer.
Trends in genetics : TIG 1993;9(4):138-41.
1993: Oliner J D; Pietenpol J A; Thiagalingam S; Gyuris J; Kinzler K W; Vogelstein B
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53.
Nature 1993;362(6423):857-60.
1993: Smith K J; Johnson K A; Bryan T M; Hill D E; Markowitz S; Willson J K; Paraskeva C; Petersen G M; Hamilton S R; Vogelstein B
The APC gene product in normal and tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2846-50.
1993: Hedrick L; Cho K R; Vogelstein B
Cell adhesion molecules as tumour suppressors.
Trends in cell biology 1993;3(2):36-9.
1993: Luongo C; Gould K A; Su L K; Kinzler K W; Vogelstein B; Dietrich W; Lander E S; Moser A R
Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.
Genomics 1993;15(1):3-8.
1992: Schneider S S; Hiemstra J L; Zehnbauer B A; Taillon-Miller P; Le Paslier D L; Vogelstein B; Brodeur G M
Isolation and structural analysis of a 1.2-megabase N-myc amplicon from a human neuroblastoma.
Molecular and cellular biology 1992;12(12):5563-70.
1992: Kastan M B; Zhan Q; el-Deiry W S; Carrier F; Jacks T; Walsh W V; Plunkett B S; Vogelstein B; Fornace A J
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia.
Cell 1992;71(4):587-97.
1992: Kinzler K W; Vogelstein B
The colorectal cancer gene hunt: current findings.
Hospital practice (Office ed.) 1992;27(11):51-8.
1992: Mulder J W; Offerhaus G J; de Feyter E P; Floyd J J; Kern S E; Vogelstein B; Hamilton S R
The relationship of quantitative nuclear morphology to molecular genetic alterations in the adenoma-carcinoma sequence of the large bowel.
The American journal of pathology 1992;141(4):797-804.
1992: Lawlor K G; Telang N T; Osborne M P; Schaapveld R Q; Cho K R; Vogelstein B; Narayanan R
Antisense RNA to the putative tumor suppressor gene "deleted in colorectal cancer" transforms fibroblasts.
Annals of the New York Academy of Sciences 1992;660():283-5.
1992: Nakamura Y; Nishisho I; Kinzler K W; Vogelstein B; Miyoshi Y; Miki Y; Ando H; Horii A
Mutations of the APC (adenomatous polyposis coli) gene in FAP (familial polyposis coli) patients and in sporadic colorectal tumors.
The Tohoku journal of experimental medicine 1992;168(2):141-7.
1992: Powell S M; Zilz N; Beazer-Barclay Y; Bryan T M; Hamilton S R; Thibodeau S N; Vogelstein B; Kinzler K W
APC mutations occur early during colorectal tumorigenesis.
Nature 1992;359(6392):235-7.
1992: Cho K R; Vogelstein B
Genetic alterations in the adenoma--carcinoma sequence.
Cancer 1992;70(6 Suppl):1727-31.
1992: Shah K V; Daniel R W; Simons J W; Vogelstein B
Investigation of colon cancers for human papillomavirus genomic sequences by polymerase chain reaction.
Journal of surgical oncology 1992;51(1):5-7.
1992: Vogelstein B; Kinzler K W
p53 function and dysfunction.
Cell 1992;70(4):523-6.
1992: Simons J W; Oliner J D; Cho K R; Kinzler K W; Vogelstein B
SAM 1.1 and JOSH 4.4: two RFLPs within the human DCC gene.
Human molecular genetics 1992;1(5):352.
1992: Justice M J; Gilbert D J; Kinzler K W; Vogelstein B; Buchberg A M; Ceci J D; Matsuda Y; Chapman V M; Patriotis C; Makris A
A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18.
Genomics 1992;13(4):1281-8.
1992: Oliner J D; Kinzler K W; Meltzer P S; George D L; Vogelstein B
Amplification of a gene encoding a p53-associated protein in human sarcomas.
Nature 1992;358(6381):80-3.
1992: Kern S E; Pietenpol J A; Thiagalingam S; Seymour A; Kinzler K W; Vogelstein B
Oncogenic forms of p53 inhibit p53-regulated gene expression.
Science (New York, N.Y.) 1992;256(5058):827-30.
1992: Sidransky D; Tokino T; Helzlsouer K; Zehnbauer B; Rausch G; Shelton B; Prestigiacomo L; Vogelstein B; Davidson N
Inherited p53 gene mutations in breast cancer.
Cancer research 1992;52(10):2984-6.
1992: Offerhaus G J; De Feyter E P; Cornelisse C J; Tersmette K W; Floyd J; Kern S E; Vogelstein B; Hamilton S R
The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma.
Gastroenterology 1992;102(5):1612-9.
1992: Su L K; Kinzler K W; Vogelstein B; Preisinger A C; Moser A R; Luongo C; Gould K A; Dove W F
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene.
Science (New York, N.Y.) 1992;256(5057):668-70.
1992: Sidransky D; Tokino T; Hamilton S R; Kinzler K W; Levin B; Frost P; Vogelstein B
Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors.
Science (New York, N.Y.) 1992;256(5053):102-5.
1992: Wong A J; Ruppert J M; Bigner S H; Grzeschik C H; Humphrey P A; Bigner D S; Vogelstein B
Structural alterations of the epidermal growth factor receptor gene in human gliomas.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2965-9.
1992: Gerwin B I; Spillare E; Forrester K; Lehman T A; Kispert J; Welsh J A; Pfeifer A M; Lechner J F; Baker S J; Vogelstein B
Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2759-63.
1992: Fong C T; White P S; Peterson K; Sapienza C; Cavenee W K; Kern S E; Vogelstein B; Cantor A B; Look A T; Brodeur G M
Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas.
Cancer research 1992;52(7):1780-5.
1992: el-Deiry W S; Kern S E; Pietenpol J A; Kinzler K W; Vogelstein B
Definition of a consensus binding site for p53.
Nature genetics 1992;1(1):45-9.
1992: Narayanan R; Lawlor K G; Schaapveld R Q; Cho K R; Vogelstein B; Bui-Vinh Tran P; Osborne M P; Telang N T
Antisense RNA to the putative tumor-suppressor gene DCC transforms Rat-1 fibroblasts.
Oncogene 1992;7(3):553-61.
1992: Nigro J M; Sikorski R; Reed S I; Vogelstein B
Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae.
Molecular and cellular biology 1992;12(3):1357-65.
1992: Bennett W P; Hollstein M C; Hsu I C; Sidransky D; Lane D P; Vogelstein B; Harris C C
Mutational spectra and immunohistochemical analyses of p53 in human cancers.
Chest 1992;101(3 Suppl):19S-20S.
1992: Sidransky D; Frost P; Von Eschenbach A; Oyasu R; Preisinger A C; Vogelstein B
Clonal origin bladder cancer.
The New England journal of medicine 1992;326(11):737-40.
1992: Goyette M C; Cho K; Fasching C L; Levy D B; Kinzler K W; Paraskeva C; Vogelstein B; Stanbridge E J
Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer.
Molecular and cellular biology 1992;12(3):1387-95.
1992: Sidransky D; Mikkelsen T; Schwechheimer K; Rosenblum M L; Cavanee W; Vogelstein B
Clonal expansion of p53 mutant cells is associated with brain tumour progression.
Nature 1992;355(6363):846-7.
1992: Miki Y; Nishisho I; Horii A; Miyoshi Y; Utsunomiya J; Kinzler K W; Vogelstein B; Nakamura Y
Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer.
Cancer research 1992;52(3):643-5.
1992: Miyoshi Y; Nishisho I; Miki Y; Mori T; Kinzler K W; Vogelstein B; Nakamura Y
Insertion/deletion polymorphism and other restriction fragment length polymorphisms in the MCC gene.
Japanese journal of cancer research : Gann 1992;83(1):10-4.
1992: Vogelstein B; Kinzler K W
Carcinogens leave fingerprints.
Nature 1992;355(6357):209-10.
1992: Cho K R; Vogelstein B
Suppressor gene alterations in the colorectal adenoma-carcinoma sequence.
Journal of cellular biochemistry. Supplement 1992;16G():137-41.
1992: Plaetke R; Weber J; Wood S; Dean M; Jeffreys A J; Weiffenbach B; Vergnaud G; Vogelstein B; White R
Report of the second international workshop on human chromosome 5 mapping: consensus genetic map.
Cytogenetics and cell genetics 1992;61(4):237-42.
1992: Hedrick L; Cho K R; Boyd J; Risinger J; Vogelstein B
DCC: a tumor suppressor gene expressed on the cell surface.
Cold Spring Harbor symposia on quantitative biology 1992;57():345-51.
1992: Nagase H; Miyoshi Y; Horii A; Aoki T; Petersen G M; Vogelstein B; Maher E; Ogawa M; Maruyama M; Utsunomiya J
Screening for germ-line mutations in familial adenomatous polyposis patients: 61 new patients and a summary of 150 unrelated patients.
Human mutation 1992;1(6):467-73.
1991: Kastan M B; Onyekwere O; Sidransky D; Vogelstein B; Craig R W
Participation of p53 protein in the cellular response to DNA damage.
Cancer research 1991;51(23 Pt 1):6304-11.
1991: Parry P J; Markie D; Fearon E R; Nigro J M; Vogelstein B; Bodmer W F
PCR-based detection of two MspI polymorphic sites at D18S8.
Nucleic acids research 1991;19(24):6983.
1991: Devilee P; van Vliet M; Cho K R; Vogelstein B
HindIII polymorphism in the DCC gene.
Nucleic acids research 1991;19(24):6965.
1991: Casey G; Lo-Hsueh M; Lopez M E; Vogelstein B; Stanbridge E J
Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene.
Oncogene 1991;6(10):1791-7.
1991: Millikin D; Meese E; Vogelstein B; Witkowski C; Trent J
Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma.
Cancer research 1991;51(20):5449-53.
1991: Saylors R L; Sidransky D; Friedman H S; Bigner S H; Bigner D D; Vogelstein B; Brodeur G M
Infrequent p53 gene mutations in medulloblastomas.
Cancer research 1991;51(17):4721-3.
1991: Peltomäki P; Sistonen P; Mecklin J P; Pylkkänen L; Järvinen H; Simons J W; Cho K R; Vogelstein B; de la Chapelle A
Evidence supporting exclusion of the DCC gene and a portion of chromosome 18q as the locus for susceptibility to hereditary nonpolyposis colorectal carcinoma in five kindreds.
Cancer research 1991;51(16):4135-40.
1991: Kinzler K W; Nilbert M C; Su L K; Vogelstein B; Bryan T M; Levy D B; Smith K J; Preisinger A C; Hedge P; McKechnie D
Identification of FAP locus genes from chromosome 5q21.
Science (New York, N.Y.) 1991;253(5020):661-5.
1991: Hollstein M; Sidransky D; Vogelstein B; Harris C C
p53 mutations in human cancers.
Science (New York, N.Y.) 1991;253(5015):49-53.
1991: Kovach J S; McGovern R M; Cassady J D; Swanson S K; Wold L E; Vogelstein B; Sommer S S
Direct sequencing from touch preparations of human carcinomas: analysis of p53 mutations in breast carcinomas.
Journal of the National Cancer Institute 1991;83(14):1004-9.
1991: Meltzer S J; Yin J; Huang Y; McDaniel T K; Newkirk C; Iseri O; Vogelstein B; Resau J H
Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4976-80.
1991: Kern S E; Kinzler K W; Bruskin A; Jarosz D; Friedman P; Prives C; Vogelstein B
Identification of p53 as a sequence-specific DNA-binding protein.
Science (New York, N.Y.) 1991;252(5013):1708-11.
1991: Bargonetti J; Friedman P N; Kern S E; Vogelstein B; Prives C
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication.
Cell 1991;65(6):1083-91.
1991: Kinzler K W; Nilbert M C; Vogelstein B; Bryan T M; Levy D B; Smith K J; Preisinger A C; Hamilton S R; Hedge P; Markham A
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers.
Science (New York, N.Y.) 1991;251(4999):1366-70.
1991: Ruppert J M; Vogelstein B; Kinzler K W
The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A.
Molecular and cellular biology 1991;11(3):1724-8.
1991: Nigro J M; Cho K R; Fearon E R; Kern S E; Ruppert J M; Oliner J D; Kinzler K W; Vogelstein B
Scrambled exons.
Cell 1991;64(3):607-13.
1991: Kern S E; Kinzler K W; Baker S J; Nigro J M; Rotter V; Levine A J; Friedman P; Prives C; Vogelstein B
Mutant p53 proteins bind DNA abnormally in vitro.
Oncogene 1991;6(1):131-6.
1991: Schneider S S; Zehnbauer B A; Vogelstein B; Brodeur G M
Yeast artificial chromosome (YAC) vector cloning of the MYCN amplified domain in neuroblastomas.
Progress in clinical and biological research 1991;366():71-6.
1991: Itaya T; Fearon E; Fiesinger T; Hunt B; Vogelstein B; Frost P
Immunogenicity of a non-class I MHC expressing murine tumor transfected with the influenza virus hemagglutinin or murine interleukin-2 genes.
Cancer immunology, immunotherapy : CII 1991;33(4):267-73.
1991: Nakamura Y; Nishisho I; Kinzler K W; Vogelstein B; Miyoshi Y; Miki Y; Ando H; Horii A; Nagase H
Mutations of the adenomatous polyposis coli gene in familial polyposis coli patients and sporadic colorectal tumors.
Princess Takamatsu symposia 1991;22():285-92.
1990: Hinds P W; Finlay C A; Quartin R S; Baker S J; Fearon E R; Vogelstein B; Levine A J
Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(12):571-80.
1990: Vogelstein B
Cancer. A deadly inheritance.
Nature 1990;348(6303):681-2.
1990: Bigner S H; Humphrey P A; Wong A J; Vogelstein B; Mark J; Friedman H S; Bigner D D
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.
Cancer research 1990;50(24):8017-22.
1990: Paulien S; Turc-Carel C; Dal Cin P; Jani-Sait S; Sreekantaiah C; Leong S P; Vogelstein B; Kinzler K W; Sandberg A A; Gemmill R M
Myxoid liposarcoma with t(12;16) (q13;p11) contains site-specific differences in methylation patterns surrounding a zinc-finger gene mapped to the breakpoint region on chromosome 12.
Cancer research 1990;50(24):7902-7.
1990: Baker S J; Preisinger A C; Jessup J M; Paraskeva C; Markowitz S; Willson J K; Hamilton S; Vogelstein B
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.
Cancer research 1990;50(23):7717-22.
1990: Friedman P N; Kern S E; Vogelstein B; Prives C
Wild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9275-9.
1990: Diller L; Kassel J; Nelson C E; Gryka M A; Litwak G; Gebhardt M; Bressac B; Ozturk M; Baker S J; Vogelstein B
p53 functions as a cell cycle control protein in osteosarcomas.
Molecular and cellular biology 1990;10(11):5772-81.
1990: Ruppert J M; Vogelstein B; Arheden K; Kinzler K W
GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity.
Molecular and cellular biology 1990;10(10):5408-15.
1990: Bigner S H; Vogelstein B
Cytogenetics and molecular genetics of malignant gliomas and medulloblastoma.
Brain pathology (Zurich, Switzerland) 1990;1(1):12-8.
1990: Baker S J; Markowitz S; Fearon E R; Willson J K; Vogelstein B
Suppression of human colorectal carcinoma cell growth by wild-type p53.
Science (New York, N.Y.) 1990;249(4971):912-5.
1990: Vogelstein B; Civin C I; Preisinger A C; Krischer J P; Steuber P; Ravindranath Y; Weinstein H; Elfferich P; Bos J
RAS gene mutations in childhood acute myeloid leukemia: a Pediatric Oncology Group study.
Genes, chromosomes & cancer 1990;2(2):159-62.
1990: Fearon E R; Vogelstein B
A genetic model for colorectal tumorigenesis.
Cell 1990;61(5):759-67.
1990: Humphrey P A; Wong A J; Vogelstein B; Zalutsky M R; Fuller G N; Archer G E; Friedman H S; Kwatra M M; Bigner S H; Bigner D D
Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4207-11.
1990: Kinzler K W; Vogelstein B
EcoRI polymorphism within the GLI gene (chromosome 12q13.3-14.1).
Nucleic acids research 1990;18(9):2834.
1990: Bigner S H; Friedman H S; Vogelstein B; Oakes W J; Bigner D D
Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts.
Cancer research 1990;50(8):2347-50.
1990: Fearon E R; Pardoll D M; Itaya T; Golumbek P; Levitsky H I; Simons J W; Karasuyama H; Vogelstein B; Frost P
Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response.
Cell 1990;60(3):397-403.
1990: Kinzler K W; Vogelstein B
The GLI gene encodes a nuclear protein which binds specific sequences in the human genome.
Molecular and cellular biology 1990;10(2):634-42.
1990: Bigner S H; Vogelstein B; Mark J; Friedman H S; Bigner D D
Cytogenetics and molecular genetics: their status and role in understanding the behavior of central nervous system neoplasms.
Monographs in pathology 1990;(32):30-40.
1989: Kern S E; Fearon E R; Tersmette K W; Enterline J P; Leppert M; Nakamura Y; White R; Vogelstein B; Hamilton S R
Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected]
JAMA : the journal of the American Medical Association 1989;261(21):3099-103.
1989: Kinzler K W; Vogelstein B
Whole genome PCR: application to the identification of sequences bound by gene regulatory proteins.
Nucleic acids research 1989;17(10):3645-53.
1989: Schackert H K; Itaya T; Schackert G; Fearon E; Vogelstein B; Frost P
Systemic immunity against a murine colon tumor (CT-26) produced by immunization with syngeneic cells expressing a transfected viral gene product.
International journal of cancer. Journal international du cancer 1989;43(5):823-7.
1989: Baker S J; Fearon E R; Nigro J M; Hamilton S R; Preisinger A C; Jessup J M; vanTuinen P; Ledbetter D H; Barker D F; Nakamura Y; White R; Vogelstein B
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas.
Science (New York, N.Y.) 1989;244(4901):217-21.
1989: Vogelstein B; Fearon E R; Kern S E; Hamilton S R; Preisinger A C; Nakamura Y; White R
Allelotype of colorectal carcinomas.
Science (New York, N.Y.) 1989;244(4901):207-11.
1989: Arheden K; Rønne M; Mandahl N; Heim S; Kinzler K W; Vogelstein B; Mitelman F
In situ hybridization localizes the human putative oncogene GLI to chromosome subbands 12q13.3-14.1.
Human genetics 1989;82(1):1-2.
1988: Fearon E R; Kohn D B; Winkelstein J A; Vogelstein B; Blaese R M
Carrier detection in the Wiskott Aldrich syndrome.
Blood 1988;72(5):1735-9.
1988: Vogelstein B; Fearon E R; Hamilton S R; Kern S E; Preisinger A C; Leppert M; Nakamura Y; White R; Smits A M; Bos J L
Genetic alterations during colorectal-tumor development.
The New England journal of medicine 1988;319(9):525-32.
1988: Ruppert J M; Kinzler K W; Wong A J; Bigner S H; Kao F T; Law M L; Seuanez H N; O'Brien S J; Vogelstein B
The GLI-Kruppel family of human genes.
Molecular and cellular biology 1988;8(8):3104-13.
1988: Fearon E R; Itaya T; Hunt B; Vogelstein B; Frost P
Induction in a murine tumor of immunogenic tumor variants by transfection with a foreign gene.
Cancer research 1988;48(11):2975-80.
1988: Bigner S H; Burger P C; Wong A J; Werner M H; Hamilton S R; Muhlbaier L H; Vogelstein B; Bigner D D
Gene amplification in malignant human gliomas: clinical and histopathologic aspects.
Journal of neuropathology and experimental neurology 1988;47(3):191-205.
1988: Humphrey P A; Wong A J; Vogelstein B; Friedman H S; Werner M H; Bigner D D; Bigner S H
Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts.
Cancer research 1988;48(8):2231-8.
1988: Hamilton S R; Vogelstein B
Point mutations in human neoplasia.
The Journal of pathology 1988;154(3):205-6.
1988: Kinzler K W; Ruppert J M; Bigner S H; Vogelstein B
The GLI gene is a member of the Kruppel family of zinc finger proteins.
Nature 1988;332(6162):371-4.
1988: Zehnbauer B A; Small D; Brodeur G M; Seeger R; Vogelstein B
Characterization of N-myc amplification units in human neuroblastoma cells.
Molecular and cellular biology 1988;8(2):522-30.
1987: Bigner S H; Wong A J; Mark J; Muhlbaier L H; Kinzler K W; Vogelstein B; Bigner D D
Relationship between gene amplification and chromosomal deviations in malignant human gliomas.
Cancer genetics and cytogenetics 1987;29(1):165-70.
1987: Wong A J; Bigner S H; Bigner D D; Kinzler K W; Hamilton S R; Vogelstein B
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6899-903.
1987: Fearon E R; Hamilton S R; Vogelstein B
Clonal analysis of human colorectal tumors.
Science (New York, N.Y.) 1987;238(4824):193-7.
1987: Vogelstein B; Fearon E R; Hamilton S R; Preisinger A C; Willard H F; Michelson A M; Riggs A D; Orkin S H
Clonal analysis using recombinant DNA probes from the X-chromosome.
Cancer research 1987;47(18):4806-13.
1987: Baylin S B; Fearon E R; Vogelstein B; de Bustros A; Sharkis S J; Burke P J; Staal S P; Nelkin B D
Hypermethylation of the 5' region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies.
Blood 1987;70(2):412-7.
1987: Bos J L; Fearon E R; Hamilton S R; Verlaan-de Vries M; van Boom J H; van der Eb A J; Vogelstein B
Prevalence of ras gene mutations in human colorectal cancers.
Nature 1987;327(6120):293-7.
1987: Kinzler K W; Bigner S H; Bigner D D; Trent J M; Law M L; O'Brien S J; Wong A J; Vogelstein B
Identification of an amplified, highly expressed gene in a human glioma.
Science (New York, N.Y.) 1987;236(4797):70-3.
1987: Fearon E R; Winkelstein J A; Civin C I; Pardoll D M; Vogelstein B
Carrier detection in X-linked agammaglobulinemia by analysis of X-chromosome inactivation.
The New England journal of medicine 1987;316(8):427-31.
1987: Vogelstein B
Rapid purification of DNA from agarose gels by centrifugation through a disposable plastic column.
Analytical biochemistry 1987;160(1):115-8.
1987: Feinberg A P; Vogelstein B
Alterations in DNA methylation in human colon neoplasia.
Seminars in surgical oncology 1987;3(3):149-51.
1986: Fearon E R; Burke P J; Zehnbauer B A; Vogelstein B; Schiffer C A
Differentiation of blast cells in acute nonlymphocytic leukemia.
The New England journal of medicine 1986;315(23):1488.
1986: Fearon E R; Burke P J; Schiffer C A; Zehnbauer B A; Vogelstein B
Differentiation of leukemia cells to polymorphonuclear leukocytes in patients with acute nonlymphocytic leukemia.
The New England journal of medicine 1986;315(1):15-24.
1986: Wong A J; Ruppert J M; Eggleston J; Hamilton S R; Baylin S B; Vogelstein B
Gene amplification of c-myc and N-myc in small cell carcinoma of the lung.
Science (New York, N.Y.) 1986;233(4762):461-4.
1986: Zehnbauer B A; Pardoll D M; Burke P J; Graham M L; Vogelstein B
Immunoglobulin gene rearrangements in remission bone marrow specimens from patients with acute lymphoblastic leukemia.
Blood 1986;67(3):835-8.
1986: Kinzler K W; Zehnbauer B A; Brodeur G M; Seeger R C; Trent J M; Meltzer P S; Vogelstein B
Amplification units containing human N-myc and c-myc genes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(4):1031-5.
1986: Trent J; Meltzer P; Rosenblum M; Harsh G; Kinzler K; Mashal R; Feinberg A; Vogelstein B
Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(2):470-3.
1986: Meltzer P; Kinzler K; Vogelstein B; Trent J M
Gene amplification in cancer: a molecular cytogenetic approach.
Cancer genetics and cytogenetics 1986;19(1-2):93-9.
1985: Small D; Vogelstein B
The anatomy of supercoiled loops in the Drosophila 7F locus.
Nucleic acids research 1985;13(21):7703-13.
1985: Fearon E R; Feinberg A P; Hamilton S H; Vogelstein B
Loss of genes on the short arm of chromosome 11 in bladder cancer.
Nature 1985;318(6044):377-80.
1985: Goelz S E; Hamilton S R; Vogelstein B
Purification of DNA from formaldehyde fixed and paraffin embedded human tissue.
Biochemical and biophysical research communications 1985;130(1):118-26.
1985: Small D; Nelkin B; Vogelstein B
The association of transcribed genes with the nuclear matrix of Drosophila cells during heat shock.
Nucleic acids research 1985;13(7):2413-31.
1985: Goelz S E; Vogelstein B; Hamilton S R; Feinberg A P
Hypomethylation of DNA from benign and malignant human colon neoplasms.
Science (New York, N.Y.) 1985;228(4696):187-90.
1985: Vogelstein B; Fearon E R; Hamilton S R; Feinberg A P
Use of restriction fragment length polymorphisms to determine the clonal origin of human tumors.
Science (New York, N.Y.) 1985;227(4687):642-5.
1984: Fearon E R; Vogelstein B; Feinberg A P
Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours.
Nature 1984;309(5964):176-8.
1984: Feinberg A P; Vogelstein B
"A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.
Analytical biochemistry 1984;137(1):266-7.
1983: Robinson S I; Small D; Idzerda R; McKnight G S; Vogelstein B
The association of transcriptionally active genes with the nuclear matrix of the chicken oviduct.
Nucleic acids research 1983;11(15):5113-30.
1983: Feinberg A P; Vogelstein B
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
Analytical biochemistry 1983;132(1):6-13.
1983: Feinberg A P; Vogelstein B; Droller M J; Baylin S B; Nelkin B D
Mutation affecting the 12th amino acid of the c-Ha-ras oncogene product occurs infrequently in human cancer.
Science (New York, N.Y.) 1983;220(4602):1175-7.
1983: Feinberg A P; Vogelstein B
Hypomethylation of ras oncogenes in primary human cancers.
Biochemical and biophysical research communications 1983;111(1):47-54.
1983: Feinberg A P; Vogelstein B
Hypomethylation distinguishes genes of some human cancers from their normal counterparts.
Nature 1983;301(5895):89-92.
1982: Small D; Nelkin B; Vogelstein B
Nonrandom distribution of repeated DNA sequences with respect to supercoiled loops and the nuclear matrix.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(19):5911-5.
1982: Vogelstein B; Hunt B F
A subset of small nuclear ribonucleoprotein particle antigens is a component of the nuclear matrix.
Biochemical and biophysical research communications 1982;105(3):1224-32.
1982: Dintzis R Z; Vogelstein B; Dintzis H M
Specific cellular stimulation in the primary immune response: experimental test of a quantized model.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(3):884-8.
1982: Robinson S I; Nelkin B D; Vogelstein B
The ovalbumin gene is associated with the nuclear matrix of chicken oviduct cells.
Cell 1982;28(1):99-106.
1982: Vogelstein B; Dintzis R Z; Dintzis H M
Specific cellular stimulation in the primary immune response: a quantized model.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(2):395-9.
1981: Robinson S I; Nelkin B; Kaufmann S; Vogelstein B
Increased phosphorylation rate of intermediate filaments during mitotic arrest.
Experimental cell research 1981;133(2):445-8.
1981: Hunt B F; Vogelstein B
Association of newly replicated DNA with the nuclear matrix of Physarum polycephalum.
Nucleic acids research 1981;9(2):349-63.
1980: Nelkin B D; Pardoll D M; Vogelstein B
Localization of SV40 genes within supercoiled loop domains.
Nucleic acids research 1980;8(23):5623-33.
1980: Vogelstein B; Pardoll D M; Coffey D S
Supercoiled loops and eucaryotic DNA replicaton.
Cell 1980;22(1 Pt 1):79-85.
1980: Nelkin B; Strayer D; Vogelstein B
Divergence of primate ribosomal RNA genes as assayed by restriction enzyme analysis.
Gene 1980;11(1-2):89-96.
1980: Pardoll D M; Vogelstein B
Sequence analysis of nuclear matrix associated DNA from rat liver.
Experimental cell research 1980;128(2):466-70.
1980: Pardoll D M; Vogelstein B; Coffey D S
A fixed site of DNA replication in eucaryotic cells.
Cell 1980;19(2):527-36.
1980: Nelkin B; Nichols C; Vogelstein B
Protein factor(s) from mitotic CHO cells induce meiotic maturation in Xenopus laevis oocytes.
FEBS letters 1980;109(2):233-8.
1979: Vogelstein B; Gillespie D
Preparative and analytical purification of DNA from agarose.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(2):615-9.
1978: Shaper J H; Pardoll D M; Kaufmann S H; Barrack E R; Vogelstein B; Coffey D S
The relationship of the nuclear matrix to cellular structure and function.
Advances in enzyme regulation 1978;17():213-48.
1977: Vogelstein B; Kowarski A A; Lietman P S
Continuous sampling as a pharmacokinetic tool.
Clinical pharmacology and therapeutics 1977;22(2):131-9.
1977: Vogelstein B; Kowarski A; Lietman P S
The pharmacokinetics of amikacin in children.
The Journal of pediatrics 1977;91(2):333-9.
1977: Vogelstein B; Gillespie D
RNA-DNA hybridization in solution without DNA reannealing.
Biochemical and biophysical research communications 1977;75(4):1127-32.
1976: Dintzis H M; Dintzis R Z; Vogelstein B
Molecular determinants of immunogenicity: the immunon model of immune response.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(10):3671-5.
1976: Prystowsky S D; Vogelstein B; Ettinger D S; Merz W G; Kaizer H; Sulica V I; Zinkham W H
Invasive aspergillosis.
The New England journal of medicine 1976;295(12):655-8.

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