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Eberhard Voit

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Physiology

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Sphingolipids

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Publications

TOP 3
Zhen Qi; F Tretter; D Fieni; Eberhard O Voit
The neurochemical mobile with non-linear interaction matrix: an exploratory computational model.
Weiwei Yin; Eberhard O Voit
Function and design of the Nox1 system in vascular smooth muscle cells.
Eberhard O Voit; Z Qi; Z Qui; S Kikuchi
Mesoscopic models of neurotransmission as intermediates between disease simulators and tools for discovering design principles.

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All Publications

2013: Zhen Qi; F Tretter; D Fieni; Eberhard O Voit
The neurochemical mobile with non-linear interaction matrix: an exploratory computational model.
Pharmacopsychiatry 2013;46 Suppl 1():S53-63.
2013: Weiwei Yin; Eberhard O Voit
Function and design of the Nox1 system in vascular smooth muscle cells.
BMC systems biology 2013;7():20.
2012: Eberhard O Voit; Z Qi; Z Qui; S Kikuchi
Mesoscopic models of neurotransmission as intermediates between disease simulators and tools for discovering design principles.
Pharmacopsychiatry 2012;45 Suppl 1():S22-30.
2012: Yun Lee; Richard A Dixon; Luis Escamilla-Treviño; Eberhard O Voit
Functional analysis of metabolic channeling and regulation in lignin biosynthesis: a computational approach.
PLoS computational biology 2012;8(11):e1002769.
2012: Eberhard O Voit; Wendy C Newstetter; Melissa L Kemp
A feel for systems.
Molecular systems biology 2012;8():609.
2012: I-Chun Chou; Eberhard O Voit
Estimation of dynamic flux profiles from metabolic time series data.
BMC systems biology 2012;6():84.
2011: Yun Lee; Fang Chen; Lina Gallego-Giraldo; Richard A Dixon; Eberhard O Voit
Integrative analysis of transgenic alfalfa (Medicago sativa L.) suggests new metabolic control mechanisms for monolignol biosynthesis.
PLoS computational biology 2011;7(5):e1002047.
2011: Zhen Qi; S Kikuchi; F Tretter; Eberhard O Voit
Effects of dopamine and glutamate on synaptic plasticity: a computational modeling approach for drug abuse as comorbidity in mood disorders.
Pharmacopsychiatry 2011;44 Suppl 1():S62-75.
2011: Yun Lee; Po-Wei Chen; Eberhard O Voit
Analysis of operating principles with S-system models.
Mathematical biosciences 2011;231(1):49-60.
2011: Luis Fonseca; Claudia Sánchez; Helena Santos; Eberhard O Voit
Complex coordination of multi-scale cellular responses to environmental stress.
Molecular bioSystems 2011;7(3):731-41.
2011: fernando alvarez; Yusuf A Hannun; Howard Riezman; Eberhard O Voit
Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae.
PloS one 2011;6(12):e28344.
2011: Jialiang Wu; Brani Vidakovic; Eberhard O Voit
Constructing stochastic models from deterministic process equations by propensity adjustment.
BMC systems biology 2011;5():187.
2011: Jialiang Wu; Zhen Qi; Eberhard O Voit
Impact of delays and noise on dopamine signal transduction.
Studies in health technology and informatics 2011;162():222-35.
2011: Juliet Ndukum; Helena Santos; Eberhard O Voit; Luis Fonseca; Susmita Datta
Statistical inference methods for sparse biological time series data.
BMC systems biology 2011;5():57.
2011: Eberhard O Voit; M L Kemp
So, you want to be a systems biologist? Determinants for creating graduate curricula in systems biology.
IET systems biology 2011;5(1):70.
2011: Alberto Marin-Sanguino; Shailendra Gupta; Eberhard O Voit; Julio Vera
Biochemical pathway modeling tools for drug target detection in cancer and other complex diseases.
Methods in enzymology 2011;487():319-69.
2010: Yun Lee; Eberhard O Voit
Mathematical modeling of monolignol biosynthesis in Populus xylem.
Mathematical biosciences 2010;228(1):78-89.
2010: Andreas Dress; Eduardo Mendoza; Eberhard O Voit
Advanced methods in molecular systems biology.
Journal of biotechnology 2010;149(3):95-7.
2010: Anna Machina; Arkady Ponosov; Eberhard O Voit
Automated piecewise power-law modeling of biological systems.
Journal of biotechnology 2010;149(3):154-65.
2010: Alberto Marin-Sanguino; Eduardo R Mendoza; Eberhard O Voit
Flux duality in nonlinear GMA systems: implications for metabolic engineering.
Journal of biotechnology 2010;149(3):166-72.
2010: Zhen Qi; Gary Miller; Eberhard O Voit
Computational modeling of synaptic neurotransmission as a tool for assessing dopamine hypotheses of schizophrenia.
Pharmacopsychiatry 2010;43 Suppl 1():S50-60.
2010: Weiwei Yin; Hanjoong Jo; Eberhard O Voit
Systems analysis of the role of bone morphogenic protein 4 in endothelial inflammation.
Annals of biomedical engineering 2010;38(2):291-307.
2010: Jialiang Wu; Zhen Qi; Eberhard O Voit
Impact of delays and noise on dopamine signal transduction.
In silico biology 2010;10(1):67-80.
2010: Eberhard O Voit; fernando alvarez; Yusuf A Hannun
Computational analysis of sphingolipid pathway systems.
Advances in experimental medicine and biology 2010;688():264-75.
2010: Zhen Qi; Gary Miller; Eberhard O Voit
The internal state of medium spiny neurons varies in response to different input signals.
BMC systems biology 2010;4():26.
2009: Zhen Qi; Gary Miller; Eberhard O Voit
Computational analysis of determinants of dopamine (DA) dysfunction in DA nerve terminals.
Synapse (New York, N.Y.) 2009;63(12):1133-42.
2009: Eberhard O Voit; G Goel; I-C Chou; Luis Fonseca
Estimation of metabolic pathway systems from different data sources.
IET systems biology 2009;3(6):513-22.
2009: I-Chun Chou; Eberhard O Voit
Recent developments in parameter estimation and structure identification of biochemical and genomic systems.
Mathematical biosciences 2009;219(2):57-83.
2009: Jialiang Wu; Eberhard O Voit
Hybrid modeling in biochemical systems theory by means of functional petri nets.
Journal of bioinformatics and computational biology 2009;7(1):107-34.
2009: Chih-Lung Ko; Eberhard O Voit; Feng-Sheng Wang
Estimating parameters for generalized mass action models with connectivity information.
BMC bioinformatics 2009;10():140.
2009: Marco Vilela; Susana Vinga; Marco A Grivet Mattoso Maia; Eberhard O Voit; Jonas Almeida
Identification of neutral biochemical network models from time series data.
BMC systems biology 2009;3():47.
2009: Eberhard O Voit
A systems-theoretical framework for health and disease: inflammation and preconditioning from an abstract modeling point of view.
Mathematical biosciences 2009;217(1):11-8.
2009: Yoram Vodovotz; Gregory Constantine; Jonathan Rubin; Marie Csete; Eberhard O Voit; Gary An
Mechanistic simulations of inflammation: current state and future prospects.
Mathematical biosciences 2009;217(1):1-10.
2008: Gautam Goel; I-Chun Chou; Eberhard O Voit
System estimation from metabolic time-series data.
Bioinformatics (Oxford, England) 2008;24(21):2505-11.
2008: Joshua S Weitz; Yuriy Mileyko; Richard I Joh; Eberhard O Voit
Collective decision making in bacterial viruses.
Biophysical journal 2008;95(6):2673-80.
2008: Zhen Qi; Gary Miller; Eberhard O Voit
A mathematical model of presynaptic dopamine homeostasis: implications for schizophrenia.
Pharmacopsychiatry 2008;41 Suppl 1():S89-98.
2008: Eberhard O Voit; Zhen Qi; Gary Miller
Steps of modeling complex biological systems.
Pharmacopsychiatry 2008;41 Suppl 1():S78-84.
2008: R C H del Rosario; Eduardo Mendoza; Eberhard O Voit
Challenges in lin-log modelling of glycolysis in Lactococcus lactis.
IET systems biology 2008;2(3):136-49.
2008: Pradeep K Polisetty; Edward P Gatzke; Eberhard O Voit
Yield optimization of regulated metabolic systems using deterministic branch-and-reduce methods.
Biotechnology and bioengineering 2008;99(5):1154-69.
2008: Ludwig Feinendegen; Philip Hahnfeldt; Eric E Schadt; Michael Stumpf; Eberhard O Voit
Systems biology and its potential role in radiobiology.
Radiation and environmental biophysics 2008;47(1):5-23.
2008: Eberhard O Voit
Modelling metabolic networks using power-laws and S-systems.
Essays in biochemistry 2008;45():29-40.
2008: Zhen Qi; Gary Miller; Eberhard O Voit
Computational systems analysis of dopamine metabolism.
PloS one 2008;3(6):e2444.
2008: Marco Vilela; I-Chun Chou; Susana Vinga; Ana Tereza R Vasconcelos; Eberhard O Voit; Jonas Almeida
Parameter optimization in S-system models.
BMC systems biology 2008;2():35.
2008: Jacqueline Garcia; John Shea; fernando alvarez; Asfia Qureshi; Chiara Luberto; Eberhard O Voit; Maurizio Del Poeta
Mathematical modeling of pathogenicity of Cryptococcus neoformans.
Molecular systems biology 2008;4():183.
2007: John H Schwacke; Eberhard O Voit
The potential for signal integration and processing in interacting MAP kinase cascades.
Journal of theoretical biology 2007;246(4):604-20.
2007: John H Schwacke; Eberhard O Voit
Concentration-dependent effects on the rapid and efficient activation of the MAP kinase signaling cascade.
Proteomics 2007;7(6):890-9.
2007: fernando alvarez; Kellie J Sims; Eberhard O Voit; Yusuf A Hannun
Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift.
Theoretical biology & medical modelling 2007;4():42.
2007: Kellie J Sims; fernando alvarez; Eberhard O Voit; Yusuf A Hannun
A guide to biochemical systems modeling of sphingolipids for the biochemist.
Methods in enzymology 2007;432():319-50.
2007: Alberto Marin-Sanguino; Eberhard O Voit; Carlos Gonzalez-Alcon; Néstor V Torres
Optimization of biotechnological systems through geometric programming.
Theoretical biology & medical modelling 2007;4():38.
2007: Marco Vilela; Carlos C H Borges; Susana Vinga; Ana Tereza R Vasconcelos; Helena Santos; Eberhard O Voit; Jonas Almeida
Automated smoother for the numerical decoupling of dynamics models.
BMC bioinformatics 2007;8():305.
2006: Gautam Goel; I-Chun Chou; Eberhard O Voit
Biological systems modeling and analysis: a biomolecular technique of the twenty-first century.
Journal of biomolecular techniques : JBT 2006;17(4):252-69.
2006: Eberhard O Voit; J Almeida; Simeone Marino; Raman Lall; G Goel; Ana Rute Neves; Helena Santos
Regulation of glycolysis in Lactococcus lactis: an unfinished systems biological case study.
Systems biology 2006;153(4):286-98.
2006: Eberhard O Voit; Ana Rute Neves; Helena Santos
The intricate side of systems biology.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(25):9452-7.
2006: Simeone Marino; Eberhard O Voit
An automated procedure for the extraction of metabolic network information from time series data.
Journal of bioinformatics and computational biology 2006;4(3):665-91.
2006: I-Chun Chou; Harald Martens; Eberhard O Voit
Parameter estimation in biochemical systems models with alternating regression.
Theoretical biology & medical modelling 2006;3():25.
2006: Yian A Chen; Cheng-Chung Chou; Xinghua Lu; Elizabeth Slate; Konan Peck; Wenying Xu; Eberhard O Voit; Jonas Almeida
A multivariate prediction model for microarray cross-hybridization.
BMC bioinformatics 2006;7():101.
2006: Pradeep K Polisetty; Eberhard O Voit; Edward P Gatzke
Identification of metabolic system parameters using global optimization methods.
Theoretical biology & medical modelling 2006;3():4.
2005: Eberhard O Voit
Smooth bistable S-systems.
Systems biology 2005;152(4):207-13.
2005: W T Mocek; R Rudnicki; Eberhard O Voit
Approximation of delays in biochemical systems.
Mathematical biosciences 2005;198(2):190-216.
2005: Raman Lall; Eberhard O Voit
Parameter estimation in modulated, unbranched reaction chains within biochemical systems.
Computational biology and chemistry 2005;29(5):309-18.
2005: John H Schwacke; Eberhard O Voit
Computation and analysis of time-dependent sensitivities in Generalized Mass Action systems.
Journal of theoretical biology 2005;236(1):21-38.
2005: Anandhi Ervadi-Radhakrishnan; Eberhard O Voit
Controllability of non-linear biochemical systems.
Mathematical biosciences 2005;196(1):99-123.
2005: fernando alvarez; Kellie J Sims; L Ashley Cowart; Yasuo Okamoto; Eberhard O Voit; Yusuf A Hannun
Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae.
Nature 2005;433(7024):425-30.
2005: Eberhard O Voit; Simeone Marino; Raman Lall
Challenges for the identification of biological systems from in vivo time series data.
In silico biology 2005;5(2):83-92.
2004: Eberhard O Voit; fernando alvarez; Kellie J Sims
Analysis of dynamic labeling data.
Mathematical biosciences 2004;191(1):83-99.
2004: Eberhard O Voit; Jonas Almeida
Decoupling dynamical systems for pathway identification from metabolic profiles.
Bioinformatics (Oxford, England) 2004;20(11):1670-81.
2004: fernando alvarez; Kellie J Sims; Yusuf A Hannun; Eberhard O Voit
Integration of kinetic information on yeast sphingolipid metabolism in dynamical pathway models.
Journal of theoretical biology 2004;226(3):265-91.
2004: Kellie J Sims; Stefka Spassieva; Eberhard O Voit; Lina M Obeid
Yeast sphingolipid metabolism: clues and connections.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2004;82(1):45-61.
2004: Siren R Veflingstad; Jonas Almeida; Eberhard O Voit
Priming nonlinear searches for pathway identification.
Theoretical biology & medical modelling 2004;1():8.
2004: John H Schwacke; Eberhard O Voit
Improved methods for the mathematically controlled comparison of biochemical systems.
Theoretical biology & medical modelling 2004;1():1.
2003: António E N Ferreira; Ana Ponces Freire; Eberhard O Voit
A quantitative model of the generation of N(epsilon)-(carboxymethyl)lysine in the Maillard reaction between collagen and glucose.
The Biochemical journal 2003;376(Pt 1):109-21.
2003: Eberhard O Voit
Biochemical and genomic regulation of the trehalose cycle in yeast: review of observations and canonical model analysis.
Journal of theoretical biology 2003;223(1):55-78.
2003: Eberhard O Voit
Design principles and operating principles: the yin and yang of optimal functioning.
Mathematical biosciences 2003;182(1):81-92.
2003: Jonas Almeida; Eberhard O Voit
Neural-network-based parameter estimation in S-system models of biological networks.
Genome informatics. International Conference on Genome Informatics 2003;14():114-23.
2003: Eberhard O Voit; Monica Riley
Extending knowledge of Escherichia coli metabolism by modeling and experiment.
Genome biology 2003;4(11):235.
2002: Lori H Schwacke; Eberhard O Voit; Larry J Hansen; Randall S Wells; Greg B Mitchum; Aleta A Hohn; Patricia A Fair
Probabilistic risk assessment of reproductive effects of polychlorinated biphenyls on bottlenose dolphins (Tursiops truncatus) from the Southeast United States Coast.
Environmental toxicology and chemistry / SETAC 2002;21(12):2752-64.
2002: Eberhard O Voit
Models-of-data and models-of-processes in the post-genomic era.
Mathematical biosciences 2002;180():263-74.
2002: Eberhard O Voit
Metabolic modeling: a tool of drug discovery in the post-genomic era.
Drug discovery today 2002;7(11):621-8.
2001: Eberhard O Voit; Mario J Del Signore
Assessment of effects of experimental imprecision on optimized biochemical systems.
Biotechnology and bioengineering 2001;74(5):443-8.
2000: Eberhard O Voit; Tomas Radivoyevitch
Biochemical systems analysis of genome-wide expression data.
Bioinformatics (Oxford, England) 2000;16(11):1023-37.
2000: Eberhard O Voit
Canonical modeling: review of concepts with emphasis on environmental health.
Environmental health perspectives 2000;108 Suppl 5():895-909.
2000: Eberhard O Voit
Utility of Biochemical Systems Theory for the analysis of metabolic effects from low-dose chemical exposure.
Risk analysis : an official publication of the Society for Risk Analysis 2000;20(3):393-402.
2000: Albert Sorribas; Jaume March; Eberhard O Voit
Estimating age-related trends in cross-sectional studies using S-distributions.
Statistics in medicine 2000;19(5):697-713.
2000: Eberhard O Voit; Lori H Schwacke
Random number generation from right-skewed, symmetric, and left-skewed distributions.
Risk analysis : an official publication of the Society for Risk Analysis 2000;20(1):59-71.
1998: Raul Curto; Eberhard O Voit; Albert Sorribas; Marta Cascante
Mathematical models of purine metabolism in man.
Mathematical biosciences 1998;151(1):1-49.
1998: Raul Curto; Eberhard O Voit; Marta Cascante
Analysis of abnormalities in purine metabolism leading to gout and to neurological dysfunctions in man.
The Biochemical journal 1998;329 ( Pt 3)():477-87.
1997: Néstor V Torres; Eberhard O Voit; C Glez-Alcón; F Rodríguez
An indirect optimization method for biochemical systems: description of method and application to the maximization of the rate of ethanol, glycerol, and carbohydrate production in Saccharomyces cerevisiae.
Biotechnology and bioengineering 1997;55(5):758-72.
1997: Eberhard O Voit; Rebecca G Knapp
Derivation of the linear-logistic model and Cox's proportional hazard model from a canonical system description.
Statistics in medicine 1997;16(15):1705-29.
1997: Raul Curto; Eberhard O Voit; Albert Sorribas; Marta Cascante
Validation and steady-state analysis of a power-law model of purine metabolism in man.
The Biochemical journal 1997;324 ( Pt 3)():761-75.
1996: P H Berg; Eberhard O Voit; Roger L White
A pharmacodynamic model for the action of the antibiotic imipenem on Pseudomonas aeruginosa populations in vitro.
Bulletin of mathematical biology 1996;58(5):923-38.
1996: Néstor V Torres; Eberhard O Voit; C González-Alcón
Optimization of nonlinear biotechnological processes with linear programming: Application to citric acid production by Aspergillus niger.
Biotechnology and bioengineering 1996;49(3):247-58.
1992: Eberhard O Voit
Optimization in integrated biochemical systems.
Biotechnology and bioengineering 1992;40(5):572-82.
1992: Eberhard O Voit
Symmetries of S-systems.
Mathematical biosciences 1992;109(1):19-37.
1990: Eberhard O Voit; P N Yi
Comparison of isoeffect relationships in radiotherapy.
Bulletin of mathematical biology 1990;52(5):657-75.
1988: Eberhard O Voit; H J Anton
Estimation of cell cycle parameters from double labeling experiments.
Journal of theoretical biology 1988;131(4):435-40.
1987: Eberhard O Voit; Michael A Savageau
Accuracy of alternative representations for integrated biochemical systems.
Biochemistry 1987;26(21):6869-80.
1985: Eberhard O Voit
Cell cycles and growth laws: the CCC model.
Journal of theoretical biology 1985;114(4):589-99.
1985: Eberhard O Voit; H J Anton
Derivation of the frequency distributions of cycle durations from continuous labeling curves.
Journal of theoretical biology 1985;112(3):575-88.
1984: Eberhard O Voit
Encounters in predator-prey systems: a simple discrete model.
Bio Systems 1984;17(1):57-63.