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Sonja Von Aulock

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Sonja Von Aulock
Evidence-Based Toxicology Collaboration (EBTC). Editorial.
Stefanie Sigel; Karin Stich; Thomas Stulnig; Sonja Von Aulock; Sebastian Bunk; Susanne Deininger; Kurt Derfler; Bianca Doninger; Julia Hoffmann; Thomas Meergans; Sylvia Knapp
Apolipoprotein B100 is a suppressor of Staphylococcus aureus-induced innate immune responses in humans and mice.
Wolfram Petzl; Tobias Pfister; Carola Sauter-Louis; Hans-Joachim Schuberth; Hans-Martin Seyfert; Sonja Von Aulock; Leopold Goetze; Juliane Günther; Angela Hafner-Marx; Holm Zerbe
Lipopolysaccharide pretreatment of the udder protects against experimental Escherichia coli mastitis.

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All Publications

2013: Sonja Von Aulock
Evidence-Based Toxicology Collaboration (EBTC). Editorial.
ALTEX 2013;30(1):1.
2012: Stefanie Sigel; Karin Stich; Thomas Stulnig; Sonja Von Aulock; Sebastian Bunk; Susanne Deininger; Kurt Derfler; Bianca Doninger; Julia Hoffmann; Thomas Meergans; Sylvia Knapp
Apolipoprotein B100 is a suppressor of Staphylococcus aureus-induced innate immune responses in humans and mice.
European journal of immunology 2012;42(11):2983-9.
2012: Wolfram Petzl; Tobias Pfister; Carola Sauter-Louis; Hans-Joachim Schuberth; Hans-Martin Seyfert; Sonja Von Aulock; Leopold Goetze; Juliane Günther; Angela Hafner-Marx; Holm Zerbe
Lipopolysaccharide pretreatment of the udder protects against experimental Escherichia coli mastitis.
Innate immunity 2012;18(3):467-77.
2012: Sonja Von Aulock
Alternative methods in Europe. Editorial.
ALTEX 2012;29(3):249.
2012: Toni Lindl; Irmela Ruhdel; Ulrike Gross; Sonja Von Aulock; Manfred Völkel
Guidance on determining indispensability and balancing potential benefits of animal experiments with costs to the animals with specific consideration of EU directive 2010/63/EU.
ALTEX 2012;29(2):219-28.
2012: Sonja Von Aulock
Developing alternatives to systemic toxicity testing approaches.
ALTEX 2012;29(1):1.
2011: Marieke A D van Zoelen; Marleen I Verstege; Christian Draing; Regina de Beer; Sandrine Florquin; Paul Bresser; jaring s. van der zee; Anje A Te Velde; Sonja Von Aulock; Cornelis van't Veer; Tom van der Poll
Endogenous MCP-1 promotes lung inflammation induced by LPS and LTA.
Molecular immunology 2011;48(12-13):1468-76.
2011: Sonja Von Aulock
Validation is a key theme in this issue of ALTEX.
ALTEX 2011;28(1):1.
2010: Sebastian Bunk; Stefanie Sigel; Daniela Metzdorf; Omar Sharif; Kathy Triantafilou; Martha Triantafilou; Thomas Hartung; Sylvia Knapp; Sonja Von Aulock
Internalization and coreceptor expression are critical for TLR2-mediated recognition of lipoteichoic acid in human peripheral blood.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(6):3708-17.
2010: Sonja Von Aulock
The patchwork of toxicological research for pharmaceutical testing.
ALTEX 2010;27(1):1.
2010: Shariq M Usmani; Giorgio Fois; Susanne Albrecht; Sonja Von Aulock; Paul Dietl; Oliver H Wittekindt
2-APB and capsazepine-induced Ca2+ influx stimulates clathrin-dependent endocytosis in alveolar epithelial cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2010;25(1):91-102.
2009: Yuping Lai; Anna Di Nardo; Teruaki Nakatsuji; Anke Leichtle; Yan Yang; Anna L Cogen; Zi-Rong Wu; Lora V Hooper; Richard R Schmidt; Sonja Von Aulock; Katherine A Radek; Chun-Ming Huang; Allen F Ryan; Richard L Gallo
Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury.
Nature medicine 2009;15(12):1377-82.
2009: Quentin Espinassous; Elvira Garcia-de-Paco; Ignacio Garcia-Verdugo; Monique Synguelakis; Sonja Von Aulock; Jean-Michel Sallenave; Andrew N J McKenzie; Jean M Kanellopoulos
IL-33 enhances lipopolysaccharide-induced inflammatory cytokine production from mouse macrophages by regulating lipopolysaccharide receptor complex.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):1446-55.
2009: Jacobien J Hoogerwerf; Alex F de Vos; Marcel Levi; Paul Bresser; jaring s. van der zee; Christian Draing; Sonja Von Aulock; Tom van der Poll
Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide.
Critical care medicine 2009;37(2):619-25.
2009: Stefanie Schindler; Sonja Von Aulock; Mardas Daneshian; Thomas Hartung
Development, validation and applications of the monocyte activation test for pyrogens based on human whole blood.
ALTEX 2009;26(4):265-77.
2009: Mardas Daneshian; Sonja Von Aulock; Thomas Hartung
Assessment of pyrogenic contaminations with validated human whole-blood assay.
Nature protocols 2009;4(12):1709-21.
2008: Ida A J Giebelen; Masja Leendertse; Mark C Dessing; Joost C M Meijers; Marcel Levi; Christian Draing; Sonja Von Aulock; Tom van der Poll
Endogenous beta-adrenergic receptors inhibit lipopolysaccharide-induced pulmonary cytokine release and coagulation.
American journal of respiratory cell and molecular biology 2008;39(3):373-9.
2008: Nahuel Fittipaldi; Tsutomu Sekizaki; Daisuke Takamatsu; Josée Harel; María de la Cruz Domínguez-Punaro; Sonja Von Aulock; Christian Draing; Corinne Marois; Marylène Kobisch; Maria de la Cruz Dominguez-Punaro
D-alanylation of lipoteichoic acid contributes to the virulence of Streptococcus suis.
Infection and immunity 2008;76(8):3587-94.
2008: Mardas Daneshian; Albrecht Wendel; Thomas Hartung; Sonja Von Aulock
High sensitivity pyrogen testing in water and dialysis solutions.
Journal of immunological methods 2008;336(1):64-70.
2008: Nadra Nilsen; Susanne Deininger; Unni Nonstad; Frode Skjeldal; Harald Husebye; Dmitrii Rodionov; Sonja Von Aulock; Thomas Hartung; Egil Lien; Oddmund Bakke; Terje Espevik
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36.
Journal of leukocyte biology 2008;84(1):280-91.
2008: Jacobien J Hoogerwerf; Alex F de Vos; Paul Bresser; jaring s. van der zee; Jennie M Pater; Anita de Boer; Michael W T Tanck; Daniel L Lundell; Chung Her-Jenh; Christian Draing; Sonja Von Aulock; Tom van der Poll
Lung inflammation induced by lipoteichoic acid or lipopolysaccharide in humans.
American journal of respiratory and critical care medicine 2008;178(1):34-41.
2008: Sylvia Knapp; Sonja Von Aulock; Masja Leendertse; Isabella Haslinger; Christian Draing; Douglas T Golenbock; Tom van der Poll
Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3478-84.
2008: Christian Draing; Stephanie Traub; Susanne Deininger; Philippa Mang; Heiko M Möller; Miguel Manso; Francois Rossi; Siegfried Morath; Thomas Hartung; Sonja Von Aulock
Polypropylene glycol is a selective binding inhibitor for LTA and other structurally related TLR2 agonists.
European journal of immunology 2008;38(3):797-808.
2008: Wei Yang; Holm Zerbe; Wolfram Petzl; Ronald Brunner; Juliane Günther; Christian Draing; Sonja Von Aulock; Hans-Joachim Schuberth; Hans-Martin Seyfert
Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder.
Molecular immunology 2008;45(5):1385-97.
2008: Mark C Dessing; Marcel Schouten; Christian Draing; Marcel Levi; Sonja Von Aulock; Tom van der Poll
Role played by Toll-like receptors 2 and 4 in lipoteichoic acid-induced lung inflammation and coagulation.
The Journal of infectious diseases 2008;197(2):245-52.
2008: Oliver Dehus; Sebastian Bunk; Sonja Von Aulock; Corinna Hermann
IL-10 release requires stronger toll-like receptor 4-triggering than TNF: a possible explanation for the selective effects of heterozygous TLR4 polymorphism Asp(299)Gly on IL-10 release.
Immunobiology 2008;213(8):621-7.
2008: Susanne Deininger; Stephanie Traub; Diana Aichele; Tamara Rupp; Teodora Baris; Heiko M Möller; Thomas Hartung; Sonja Von Aulock
Presentation of lipoteichoic acid potentiates its inflammatory activity.
Immunobiology 2008;213(6):519-29.
2008: Christian Draing; Stefanie Sigel; Susanne Deininger; Stephanie Traub; Rebekka Munke; Christoph Mayer; Lars Hareng; Thomas Hartung; Sonja Von Aulock; Corinna Hermann
Cytokine induction by Gram-positive bacteria.
Immunobiology 2008;213(3-4):285-96.
2007: Susanne Deininger; Ignacio Figueroa-Perez; Stefanie Sigel; Andreas Stadelmaier; Richard R Schmidt; Thomas Hartung; Sonja Von Aulock
Use of synthetic derivatives to determine the minimal active structure of cytokine-inducing lipoteichoic acid.
Clinical and vaccine immunology : CVI 2007;14(12):1629-33.
2007: Marieke A D van Zoelen; Alex F de Vos; Greg La Rosa; Christian Draing; Sonja Von Aulock; Tom van der Poll
Intrapulmonary delivery of ethyl pyruvate attenuates lipopolysaccharide- and lipoteichoic acid-induced lung inflammation in vivo.
Shock (Augusta, Ga.) 2007;28(5):570-5.
2007: Mónica Perea Vélez; Tine L A Verhoeven; Christian Draing; Sonja Von Aulock; Markus Pfitzenmaier; Armin Geyer; Ivo Lambrichts; Corinne Grangette; Bruno Pot; Jos Vanderleyden; Sigrid C J De Keersmaecker
Functional analysis of D-alanylation of lipoteichoic acid in the probiotic strain Lactobacillus rhamnosus GG.
Applied and environmental microbiology 2007;73(11):3595-604.
2007: Liisa Räisänen; Christian Draing; Markus Pfitzenmaier; Karin Schubert; Tiina Jaakonsaari; Sonja Von Aulock; Thomas Hartung; Tapani Alatossava
Molecular interaction between lipoteichoic acids and Lactobacillus delbrueckii phages depends on D-alanyl and alpha-glucose substitution of poly(glycerophosphate) backbones.
Journal of bacteriology 2007;189(11):4135-40.
2007: Sonja Von Aulock; Thomas Hartung; Corinna Hermann
Comment on "Not lipoteichoic acid but lipoproteins appear to be the dominant immunobiologically active compounds in Staphylococcus aureus".
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2610; author reply 2610-1.
2007: Marina Hasiwa; Karin Kullmann; Sonja Von Aulock; Christoph Klein; Thomas Hartung
An in vitro pyrogen safety test for immune-stimulating components on surfaces.
Biomaterials 2007;28(7):1367-75.
2007: Francesca Mazzotti; Julia Beuttler; Richard Zeller; Ulrich Fink; Stefanie Schindler; Albrecht Wendel; Thomas Hartung; Sonja Von Aulock
In vitro pyrogen test--A new test method for solid medical devices.
Journal of biomedical materials research. Part A 2007;80(2):276-82.
2006: Christian Draing; Markus Pfitzenmaier; Sebastiana Zummo; Giuseppe Mancuso; Armin Geyer; Thomas Hartung; Sonja Von Aulock
Comparison of lipoteichoic acid from different serotypes of Streptococcus pneumoniae.
The Journal of biological chemistry 2006;281(45):33849-59.
2006: Andreas Stadelmaier; Ignacio Figueroa-Perez; Susanne Deininger; Sonja Von Aulock; Thomas Hartung; Richard R Schmidt
A Staphylococcus aureus lipoteichoic acid (LTA) derived structural variant with two diacylglycerol residues.
Bioorganic & medicinal chemistry 2006;14(18):6239-54.
2006: Mardas Daneshian; Armin Guenther; Albrecht Wendel; Thomas Hartung; Sonja Von Aulock
In vitro pyrogen test for toxic or immunomodulatory drugs.
Journal of immunological methods 2006;313(1-2):169-75.
2006: Corinna Hermann; Sonja Von Aulock; Oliver Dehus; Moritz Keller; Hiromi Okigami; Florian Gantner; Albrecht Wendel; Thomas Hartung
Endogenous cortisol determines the circadian rhythm of lipopolysaccharide-- but not lipoteichoic acid--inducible cytokine release.
European journal of immunology 2006;36(2):371-9.
2006: Stephanie Traub; Sonja Von Aulock; Thomas Hartung; Corinna Hermann
MDP and other muropeptides--direct and synergistic effects on the immune system.
Journal of endotoxin research 2006;12(2):69-85.
2005: Sonja Von Aulock; Jan Rupp; Katja Gueinzius; Matthias Maass; Corinna Hermann
Critical investigation of the CD14 promoter polymorphism: lack of a role for in vitro cytokine response and membrane CD14 expression.
Clinical and diagnostic laboratory immunology 2005;12(10):1254-6.
2005: Ilona Kindinger; Mardas Daneshian; Hans Baur; Thomas Gabrio; Andreas Hofmann; Stefan Fennrich; Sonja Von Aulock; Thomas Hartung
A new method to measure air-borne pyrogens based on human whole blood cytokine response.
Journal of immunological methods 2005;298(1-2):143-53.
2005: Siegfried Morath; Sonja Von Aulock; Thomas Hartung
Structure/function relationships of lipoteichoic acids.
Journal of endotoxin research 2005;11(6):348-56.
2004: Stefanie Schindler; Silvia Asmus; Sonja Von Aulock; Albrecht Wendel; Thomas Hartung; Stefan Fennrich
Cryopreservation of human whole blood for pyrogenicity testing.
Journal of immunological methods 2004;294(1-2):89-100.
2004: Sonja Von Aulock; Isabel Diterich; Lars Hareng; Thomas Hartung
G-CSF: boosting endogenous production--a new strategy?
Current opinion in investigational drugs (London, England : 2000) 2004;5(11):1148-52.
2004: Corinna Hermann; Katja Gueinzius; Albrecht Oehme; Sonja Von Aulock; Eberhard Straube; Thomas Hartung
Comparison of quantitative and semiquantitative enzyme-linked immunosorbent assays for immunoglobulin G against Chlamydophila pneumoniae to a microimmunofluorescence test for use with patients with respiratory tract infections.
Journal of clinical microbiology 2004;42(6):2476-9.
2004: Sonja Von Aulock; Nicolas W J Schröder; Stephanie Traub; Katja Gueinzius; Eva Lorenz; Thomas Hartung; Ralf R Schumann; Corinna Hermann
Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responses.
Infection and immunity 2004;72(3):1828-31.
2004: Sonja Von Aulock; Eva-Maria Boneberg; Isabel Diterich; Thomas Hartung
Granulocyte colony-stimulating factor (filgrastim) treatment primes for increased ex vivo inducible prostanoid release.
The Journal of pharmacology and experimental therapeutics 2004;308(2):754-9.
2004: Christian Schneider; Sonja Von Aulock; Siegfried Zedler; Christian Schinkel; Thomas Hartung; Eugen Faist
Perioperative recombinant human granulocyte colony-stimulating factor (Filgrastim) treatment prevents immunoinflammatory dysfunction associated with major surgery.
Annals of surgery 2004;239(1):75-81.
2003: Sonja Von Aulock; Nicolas W J Schröder; Katja Gueinzius; Stephanie Traub; Sebastian Hoffmann; Kathrin Graf; Stefanie Dimmeler; Thomas Hartung; Ralf R Schumann; Corinna Hermann
Heterozygous toll-like receptor 4 polymorphism does not influence lipopolysaccharide-induced cytokine release in human whole blood.
The Journal of infectious diseases 2003;188(6):938-43.
2003: Lars Hareng; Thomas Meergans; Sonja Von Aulock; Hans-Dieter Volk; Thomas Hartung
Cyclic AMP increases endogenous granulocyte colony-stimulating factor formation in monocytes and THP-1 macrophages despite attenuated TNF-alpha formation.
European journal of immunology 2003;33(8):2287-96.
2003: Sonja Von Aulock; Corinna Hermann; Thomas Hartung
Determination of the eicosanoid response to inflammatory stimuli in whole blood and its pharmacological modulation ex vivo.
Journal of immunological methods 2003;277(1-2):53-63.
2003: Susanne Deininger; Andreas Stadelmaier; Sonja Von Aulock; Siegfried Morath; Richard R Schmidt; Thomas Hartung
Definition of structural prerequisites for lipoteichoic acid-inducible cytokine induction by synthetic derivatives.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(8):4134-8.
2003: Corinna Hermann; Sonja Von Aulock; Kathrin Graf; Thomas Hartung
A model of human whole blood lymphokine release for in vitro and ex vivo use.
Journal of immunological methods 2003;275(1-2):69-79.
2003: Sonja Von Aulock; Siegfried Morath; Lars Hareng; Sylvia Knapp; Kok P M van Kessel; Jos van Strijp; Thomas Hartung
Lipoteichoic acid from Staphylococcus aureus is a potent stimulus for neutrophil recruitment.
Immunobiology 2003;208(4):413-22.
2003: Thomas Hartung; Sonja Von Aulock; Christian Schneider; Eugen Faist
How to leverage an endogenous immune defense mechanism: the example of granulocyte colony-stimulating factor.
Critical care medicine 2003;31(1 Suppl):S65-75.
2002: Sonja Von Aulock; Thomas Hartung
Potential for immune reconstitution through G-CSF treatment of HIV patients.
Archivum immunologiae et therapiae experimentalis 2002;50(2):111-20.
2000: Thomas Hartung; Sonja Von Aulock; M Freitag; Stefan Höxtermann; M Stücker; K Hoffmann; P Altmeyer; A Kottke; Albrecht Wendel
Blood cytokine response of low-dose molgramostim (rhGM-CSF)-treated patients.
Cytokine 2000;12(10):1570-4.
2000: Sonja Von Aulock; Eva-Maria Boneberg; Thomas Hartung
Intermittent G-CSF (filgrastim) treatment cannot induce lymphocytosis in volunteers.
Clinical pharmacology and therapeutics 2000;68(1):104.
1999: Thomas Hartung; W D Doecke; Daniela S Bundschuh; M A Foote; Florian Gantner; Corinna Hermann; A Lenz; S Milwee; B Rich; B Simon; Hans-Dieter Volk; Sonja Von Aulock; Albrecht Wendel
Effect of filgrastim treatment on inflammatory cytokines and lymphocyte functions.
Clinical pharmacology and therapeutics 1999;66(4):415-24.
1998: Thomas Hartung; Sonja Von Aulock; Albrecht Wendel
Role of granulocyte colony-stimulating factor in infection and inflammation.
Medical microbiology and immunology 1998;187(2):61-9.