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Tobias von der Haar

Research Profile

Living Beings

Saccharomyces cerevisiae

Physiology

Chemicals & Drugs

Phenomena

Protein Binding

Anatomy

Ribosomes

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Co-author Network

Publications

TOP 3
Dominique Chu; Tobias von der Haar
The architecture of eukaryotic translation.
Lyne Jossé; Ricardo Marchante; Tobias von der Haar; Jo Zenthon; Mick F Tuite
Probing the role of structural features of mouse PrP in yeast by expression as Sup35-PrP fusions.
Emma J Mead; Gary A Montague; C Mark Smales; Sarah K Spurgeon; Lesley M Chiverton; Elaine B Martin; Tobias von der Haar
Experimental and in silico modelling analyses of the gene expression pathway for recombinant antibody and by-product production in NS0 cell lines.

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All Publications

2012: Dominique Chu; Tobias von der Haar
The architecture of eukaryotic translation.
Nucleic acids research 2012;40(20):10098-106.
2012: Lyne Jossé; Ricardo Marchante; Tobias von der Haar; Jo Zenthon; Mick F Tuite
Probing the role of structural features of mouse PrP in yeast by expression as Sup35-PrP fusions.
Prion 2012;6(3):201-10.
2012: Emma J Mead; Gary A Montague; C Mark Smales; Sarah K Spurgeon; Lesley M Chiverton; Elaine B Martin; Tobias von der Haar
Experimental and in silico modelling analyses of the gene expression pathway for recombinant antibody and by-product production in NS0 cell lines.
PloS one 2012;7(10):e47422.
2011: Dominique Chu; David J Barnes; Tobias von der Haar
The role of tRNA and ribosome competition in coupling the expression of different mRNAs in Saccharomyces cerevisiae.
Nucleic acids research 2011;39(15):6705-14.
2010: Gloria H Merritt; Wesley R Naemi; Pierre Mugnier; Helen M Webb; Mick F Tuite; Tobias von der Haar
Decoding accuracy in eRF1 mutants and its correlation with pleiotropic quantitative traits in yeast.
Nucleic acids research 2010;38(16):5479-92.
2009: Emma J Mead; Lesley M Chiverton; C Mark Smales; Tobias von der Haar
Identification of the limitations on recombinant gene expression in CHO cell lines with varying luciferase production rates.
Biotechnology and bioengineering 2009;102(6):1593-602.
2009: Tobias von der Haar
One for all? A viral protein supplants the mRNA cap-binding complex.
The EMBO journal 2009;28(1):6-7.
2008: Patrick Studte; Sabrina Zink; Daniel Jablonowski; Christian Bär; Tobias von der Haar; Mick F Tuite; Raffael Schaffrath
tRNA and protein methylase complexes mediate zymocin toxicity in yeast.
Molecular microbiology 2008;69(5):1266-77.
2008: Tobias von der Haar
A quantitative estimation of the global translational activity in logarithmically growing yeast cells.
BMC systems biology 2008;2():87.
2007: Robert J C Gilbert; Yulya Gordiyenko; Tobias von der Haar; Andreas F-P Sonnen; Gregor Hofmann; Maria Nardelli; David I Stuart; John E G McCarthy
Reconfiguration of yeast 40S ribosomal subunit domains by the translation initiation multifactor complex.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):5788-93.
2007: Tobias von der Haar; Mick F Tuite
Regulated translational bypass of stop codons in yeast.
Trends in microbiology 2007;15(2):78-86.
2007: Tobias von der Haar
Optimized protein extraction for quantitative proteomics of yeasts.
PloS one 2007;2(10):e1078.
2007: John E G McCarthy; Steven Marsden; Tobias von der Haar
Biophysical studies of the translation initiation pathway with immobilized mRNA analogs.
Methods in enzymology 2007;430():247-64.
2007: Tobias von der Haar; Lyne Jossé; Paul Wright; Jo Zenthon; Mick F Tuite
Development of a novel yeast cell-based system for studying the aggregation of Alzheimer's disease-associated Abeta peptides in vivo.
Neuro-degenerative diseases 2007;4(2-3):136-47.
2006: Tobias von der Haar; Yuko Oku; Marina Ptushkina; Nathan J Moerke; Gerhard Wagner; John D Gross; John E G McCarthy
Folding transitions during assembly of the eukaryotic mRNA cap-binding complex.
Journal of molecular biology 2006;356(4):982-92.
2004: Tobias von der Haar; John D Gross; Gerhard Wagner; John E G McCarthy
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression.
Nature structural & molecular biology 2004;11(6):503-11.
2003: John D Gross; Nathan J Moerke; Tobias von der Haar; Alexey A Lugovskoy; Alan B Sachs; John E G McCarthy; Gerhard Wagner
Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
Cell 2003;115(6):739-50.
2003: Hui He; Tobias von der Haar; Chingakham Ranjit Singh; Miki Ii; Bin Li; Alan G Hinnebusch; John E G McCarthy; Katsura Asano
The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selection.
Molecular and cellular biology 2003;23(15):5431-45.
2003: Tobias von der Haar; John E G McCarthy
Studying the assembly of multicomponent protein and ribonucleoprotein complexes using surface plasmon resonance.
Methods (San Diego, Calif.) 2003;29(2):167-74.
2002: Tobias von der Haar; John E G McCarthy
Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap-complex function.
Molecular microbiology 2002;46(2):531-44.
2002: Tobias von der Haar; J M X Hughes; M Manjarul Karim; Marina Ptushkina; John E G McCarthy
Translation initiation and surface plasmon resonance: new technology applied to old questions.
Biochemical Society transactions 2002;30(2):155-62.
2001: Marina Ptushkina; Karine V.J. BERTHELOT; Tobias von der Haar; L Geffers; Jim Warwicker; John E G McCarthy
A second eIF4E protein in Schizosaccharomyces pombe has distinct eIF4G-binding properties.
Nucleic acids research 2001;29(22):4561-9.
2000: Tobias von der Haar; P D Ball; John E G McCarthy
Stabilization of eukaryotic initiation factor 4E binding to the mRNA 5'-Cap by domains of eIF4G.
The Journal of biological chemistry 2000;275(39):30551-5.
1999: Marina Ptushkina; Tobias von der Haar; MM Karim; J M X Hughes; John E G McCarthy
Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state.
The EMBO journal 1999;18(14):4068-75.
1999: J M X Hughes; Marina Ptushkina; MM Karim; N Koloteva; Tobias von der Haar; John E G McCarthy
Translational repression by human 4E-BP1 in yeast specifically requires human eIF4E as target.
The Journal of biological chemistry 1999;274(6):3261-4.
1998: Marina Ptushkina; Tobias von der Haar; S Vasilescu; R Frank; Ralf Birkenhäger; John E G McCarthy
Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20.
The EMBO journal 1998;17(16):4798-808.