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Gunnar von Heijne
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20
Nilsson, IngMarie
15
de Gier, Jan-Willem
13
Monné, Magnus
10
Elofsson, Arne
9
Brunak, Søren
9
Kim, Hyun
9
Sääf, A
9
Whitley, P
8
Melén, Karin
8
Luirink, Joen
8
Wallin, Ewa
7
Gafvelin, Guro
7
Hessa, Tara
7
Emanuelsson, Olof
6
Daley, Daniel
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All Publications
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2009: Jaud Simon; Fernández-Vidal Mónica; Nilsson Ingmarie; Meindl-Beinker Nadja M; Hübner Nadja C; Tobias Douglas J; von Heijne Gunnar; White Stephen H
Insertion of short transmembrane helices by the Sec61 translocon.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(28):11588-93.
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2009: Enquist Karl; Fransson Mawritz; Boekel Carolina; Bengtsson Inger; Geiger Karin; Lang Lisa; Pettersson Aron; Johansson Sofia; von Heijne Gunnar; Nilsson IngMarie
Membrane-integration characteristics of two ABC transporters, CFTR and P-glycoprotein.
Journal of molecular biology 2009;387(5):1153-64.
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2009: Hessa Tara; Reithinger Johannes H; von Heijne Gunnar; Kim Hyun
Analysis of transmembrane helix integration in the endoplasmic reticulum in S. cerevisiae.
Journal of molecular biology 2009;386(5):1222-8.
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2008: Lundin Carolina; Kim Hyun; Nilsson IngMarie; White Stephen H; von Heijne Gunnar
Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(41):15702-7.
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2008: Cassel Marika; Seppälä Susanna; von Heijne Gunnar
Confronting fusion protein-based membrane protein topology mapping with reality: the Escherichia coli ClcA H+/Cl- exchange transporter.
Journal of molecular biology 2008;381(4):860-6.
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2008: von Heijne Gunnar; Rees Douglas
Membranes: reading between the lines.
Current opinion in structural biology 2008;18(4):403-5.
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2008: Bernsel Andreas; Viklund Håkan; Falk Jenny; Lindahl Erik; von Heijne Gunnar; Elofsson Arne
Prediction of membrane-protein topology from first principles.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(20):7177-81.
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2008: Lerch-Bader Mirjam; Lundin Carolina; Kim Hyun; Nilsson Ingmarie; von Heijne Gunnar
Contribution of positively charged flanking residues to the insertion of transmembrane helices into the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4127-32.
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2008: White Stephen H; von Heijne Gunnar
How translocons select transmembrane helices.
Annual review of biophysics 2008;37():23-42.
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2008: Drew David; Newstead Simon; Sonoda Yo; Kim Hyun; von Heijne Gunnar; Iwata So
GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae.
Nature protocols 2008;3(5):784-98.
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2007: Hessa Tara; Meindl-Beinker Nadja M; Bernsel Andreas; Kim Hyun; Sato Yoko; Lerch-Bader Mirjam; Nilsson IngMarie; White Stephen H; von Heijne Gunnar
Molecular code for transmembrane-helix recognition by the Sec61 translocon.
Nature 2007;450(7172):1026-30.
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2007: Granseth Erik; Seppälä Susanna; Rapp Mikaela; Daley Daniel O; Von Heijne Gunnar
Membrane protein structural biology--how far can the bugs take us?
Molecular membrane biology 2007;24(5-6):329-32.
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2007: Newstead Simon; Kim Hyun; von Heijne Gunnar; Iwata So; Drew David
High-throughput fluorescent-based optimization of eukaryotic membrane protein overexpression and purification in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):13936-41.
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2007: Lundin Carolina; Johansson Sofia; Johnson Arthur E; Näslund Jan; von Heijne Gunnar; Nilsson IngMarie
Stable insertion of Alzheimer Abeta peptide into the ER membrane strongly correlates with its length.
FEBS letters 2007;581(20):3809-13.
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2007: Stenberg Filippa; von Heijne Gunnar; Daley Daniel O
Assembly of the cytochrome bo3 complex.
Journal of molecular biology 2007;371(3):765-73.
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2007: von Heijne Gunnar
Membrane proteins up for grabs.
Nature biotechnology 2007;25(6):646-7.
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2007: Zhang Liyan; Sato Yoko; Hessa Tara; von Heijne Gunnar; Lee Jong-Kook; Kodama Itsuo; Sakaguchi Masao; Uozumi Nobuyuki
Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K+ channel voltage sensor domain.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(20):8263-8.
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2007: von Heijne Gunnar
Formation of transmembrane helices in vivo--is hydrophobicity all that matters?
The Journal of general physiology 2007;129(5):353-6.
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2007: Rapp Mikaela; Seppälä Susanna; Granseth Erik; von Heijne Gunnar
Emulating membrane protein evolution by rational design.
Science (New York, N.Y.) 2007;315(5816):1282-4.
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2007: Elofsson Arne; von Heijne Gunnar
Membrane protein structure: prediction versus reality.
Annual review of biochemistry 2007;76():125-40.
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2007: Emanuelsson Olof; Brunak Søren; von Heijne Gunnar; Nielsen Henrik
Locating proteins in the cell using TargetP, SignalP and related tools.
Nature protocols 2007;2(4):953-71.
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2006: von Heijne Gunnar
Membrane-protein topology.
Nature reviews. Molecular cell biology 2006;7(12):909-18.
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2006: Meindl-Beinker Nadja M; Lundin Carolina; Nilsson Ingmarie; White Stephen H; von Heijne Gunnar
Asn- and Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly.
EMBO reports 2006;7(11):1111-6.
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2006: Kim Hyun; Melén Karin; Osterberg Marie; von Heijne Gunnar
A global topology map of the Saccharomyces cerevisiae membrane proteome.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(30):11142-7.
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2006: Osterberg Marie; Kim Hyun; Warringer Jonas; Melén Karin; Blomberg Anders; von Heijne Gunnar
Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(30):11148-53.
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2006: Amico Mauro; Finelli Michele; Rossi Ivan; Zauli Andrea; Elofsson Arne; Viklund Håkan; von Heijne Gunnar; Jones David; Krogh Anders; Fariselli Piero; Luigi Martelli Pier; Casadio Rita
PONGO: a web server for multiple predictions of all-alpha transmembrane proteins.
Nucleic acids research 2006;34(Web Server issue):W169-72.
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2006: Lundin Carolina; Nordström Rickard; Wagner Klaus; Windpassinger Christian; Andersson Helena; von Heijne Gunnar; Nilsson IngMarie
Membrane topology of the human seipin protein.
FEBS letters 2006;580(9):2281-4.
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2006: Marani Paola; Wagner Samuel; Baars Louise; Genevaux Pierre; de Gier Jan-Willem; Nilsson Ingmarie; Casadio Rita; von Heijne Gunnar
New Escherichia coli outer membrane proteins identified through prediction and experimental verification.
Protein science : a publication of the Protein Society 2006;15(4):884-9.
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2006: Rapp Mikaela; Granseth Erik; Seppälä Susanna; von Heijne Gunnar
Identification and evolution of dual-topology membrane proteins.
Nature structural & molecular biology 2006;13(2):112-6.
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2005: Villarejo Arsenio; Burén Stefan; Larsson Susanne; Déjardin Annabelle; Monné Magnus; Rudhe Charlotta; Karlsson Jan; Jansson Stefan; Lerouge Patrice; Rolland Norbert; von Heijne Gunnar; Grebe Markus; Bako Laszlo; Samuelsson Göran
Evidence for a protein transported through the secretory pathway en route to the higher plant chloroplast.
Nature cell biology 2005;7(12):1224-31.
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2005: Karamyshev Andrey L; Kelleher Daniel J; Gilmore Reid; Johnson Arthur E; von Heijne Gunnar; Nilsson Ingmarie
Mapping the interaction of the STT3 subunit of the oligosaccharyl transferase complex with nascent polypeptide chains.
The Journal of biological chemistry 2005;280(49):40489-93.
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2005: Freites J Alfredo; Tobias Douglas J; von Heijne Gunnar; White Stephen H
Interface connections of a transmembrane voltage sensor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(42):15059-64.
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2005: von Heijne Gunnar
Helices on the move.
Nature structural & molecular biology 2005;12(10):834-5.
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2005: Pasche Boris; Knobloch Thomas J; Bian Yansong; Liu Junjian; Phukan Sharbani; Rosman Diana; Kaklamani Virginia; Baddi Lisa; Siddiqui Farida S; Frankel Wendy; Prior Thomas W; Schuller David E; Agrawal Amit; Lang Jas; Dolan M Eileen; Vokes Everett E; Lane William S; Huang Chiang-Ching; Caldes Trinidad; Di Cristofano Antonio; Hampel Heather; Nilsson IngMarie; von Heijne Gunnar; Fodde Riccardo; Murty V V V S; de la Chapelle Albert; Weghorst Christopher M
Somatic acquisition and signaling of TGFBR1*6A in cancer.
JAMA : the journal of the American Medical Association 2005;294(13):1634-46.
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2005: Médigue Claudine; Krin Evelyne; Pascal Géraldine; Barbe Valérie; Bernsel Andreas; Bertin Philippe N; Cheung Frankie; Cruveiller Stéphane; D'Amico Salvino; Duilio Angela; Fang Gang; Feller Georges; Ho Christine; Mangenot Sophie; Marino Gennaro; Nilsson Johan; Parrilli Ermenegilda; Rocha Eduardo P C; Rouy Zoé; Sekowska Agnieszka; Tutino Maria Luisa; Vallenet David; von Heijne Gunnar; Danchin Antoine
Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125.
Genome research 2005;15(10):1325-35.
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2005: Stenberg Filippa; Chovanec Peter; Maslen Sarah L; Robinson Carol V; Ilag Leopold L; von Heijne Gunnar; Daley Daniel O
Protein complexes of the Escherichia coli cell envelope.
The Journal of biological chemistry 2005;280(41):34409-19.
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2005: Laudon Hanna; Hansson Emil M; Melén Karin; Bergman Anna; Farmery Mark R; Winblad Bengt; Lendahl Urban; von Heijne Gunnar; Näslund Jan
A nine-transmembrane domain topology for presenilin 1.
The Journal of biological chemistry 2005;280(42):35352-60.
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2005: Granseth Erik; Daley Daniel O; Rapp Mikaela; Melén Karin; von Heijne Gunnar
Experimentally constrained topology models for 51,208 bacterial inner membrane proteins.
Journal of molecular biology 2005;352(3):489-94.
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2005: Nilsson Johan; Persson Bengt; von Heijne Gunnar
Comparative analysis of amino acid distributions in integral membrane proteins from 107 genomes.
Proteins 2005;60(4):606-16.
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2005: White Stephen H; von Heijne Gunnar
Transmembrane helices before, during, and after insertion.
Current opinion in structural biology 2005;15(4):378-86.
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2005: von Heijne Gunnar
Microbiology. Translocation of anthrax toxin: lord of the rings.
Science (New York, N.Y.) 2005;309(5735):709-10.
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2005: Bernsel Andreas; Von Heijne Gunnar
Improved membrane protein topology prediction by domain assignments.
Protein science : a publication of the Protein Society 2005;14(7):1723-8.
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2005: Daley Daniel O; Rapp Mikaela; Granseth Erik; Melén Karin; Drew David; von Heijne Gunnar
Global topology analysis of the Escherichia coli inner membrane proteome.
Science (New York, N.Y.) 2005;308(5726):1321-3.
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2005: Kim Hyun; von Heijne Gunnar; Nilsson IngMarie
Membrane topology of the STT3 subunit of the oligosaccharyl transferase complex.
The Journal of biological chemistry 2005;280(21):20261-7.
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2005: Tie Jian-Ke; Nicchitta Christopher; von Heijne Gunnar; Stafford Darrel W
Membrane topology mapping of vitamin K epoxide reductase by in vitro translation/cotranslocation.
The Journal of biological chemistry 2005;280(16):16410-6.
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2005: Ding Bo; Kull Björn; Liu Zhurong; Mottagui-Tabar Salim; Thonberg Håkan; Gu Harvest F; Brookes Anthony J; Grundemar Lars; Karlsson Christina; Hamsten Anders; Arner Peter; Ostenson Claes-Göran; Efendic Suad; Monné Magnus; von Heijne Gunnar; Eriksson Per; Wahlestedt Claes
Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function.
Regulatory peptides 2005;127(1-3):45-53.
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2005: Hessa Tara; White Stephen H; von Heijne Gunnar
Membrane insertion of a potassium-channel voltage sensor.
Science (New York, N.Y.) 2005;307(5714):1427.
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2005: Granseth Erik; von Heijne Gunnar; Elofsson Arne
A study of the membrane-water interface region of membrane proteins.
Journal of molecular biology 2005;346(1):377-85.
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2005: Hessa Tara; Kim Hyun; Bihlmaier Karl; Lundin Carolina; Boekel Jorrit; Andersson Helena; Nilsson Ingmarie; White Stephen H; von Heijne Gunnar
Recognition of transmembrane helices by the endoplasmic reticulum translocon.
Nature 2005;433(7024):377-81.
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2005: Monné Magnus; Hessa Tara; Thissen Laura; von Heijne Gunnar
Competition between neighboring topogenic signals during membrane protein insertion into the ER.
The FEBS journal 2005;272(1):28-36.
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2005: Luirink Joen; von Heijne Gunnar; Houben Edith; de Gier Jan-Willem
Biogenesis of inner membrane proteins in Escherichia coli.
Annual review of microbiology 2005;59():329-55.
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2004: Kerje Susanne; Sharma Preety; Gunnarsson Ulrika; Kim Hyun; Bagchi Sonchita; Fredriksson Robert; Schütz Karin; Jensen Per; von Heijne Gunnar; Okimoto Ron; Andersson Leif
The Dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 gene.
Genetics 2004;168(3):1507-18.
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2004: White Stephen H; von Heijne Gunnar
The machinery of membrane protein assembly.
Current opinion in structural biology 2004;14(4):397-404.
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2004: Bendtsen Jannick Dyrløv; Nielsen Henrik; von Heijne Gunnar; Brunak Søren
Improved prediction of signal peptides: SignalP 3.0.
Journal of molecular biology 2004;340(4):783-95.
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2004: Stefansson Anne; Armulik Annika; Nilsson IngMarie; von Heijne Gunnar; Johansson Staffan
Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits.
The Journal of biological chemistry 2004;279(20):21200-5.
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2004: Bendtsen Jannick Dyrløv; Jensen Lars Juhl; Blom Nikolaj; Von Heijne Gunnar; Brunak Søren
Feature-based prediction of non-classical and leaderless protein secretion.
Protein engineering, design & selection : PEDS 2004;17(4):349-56.
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2004: Rapp Mikaela; Drew David; Daley Daniel O; Nilsson Johan; Carvalho Tiago; Melén Karin; De Gier Jan-Willem; Von Heijne Gunnar
Experimentally based topology models for E. coli inner membrane proteins.
Protein science : a publication of the Protein Society 2004;13(4):937-45.
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2003: Hermansson Marika; von Heijne Gunnar
Inter-helical hydrogen bond formation during membrane protein integration into the ER membrane.
Journal of molecular biology 2003;334(4):803-9.
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2003: Westerlund Isabelle; Von Heijne Gunnar; Emanuelsson Olof
LumenP--a neural network predictor for protein localization in the thylakoid lumen.
Protein science : a publication of the Protein Society 2003;12(10):2360-6.
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2003: Andersson Helena; D'Antona Aaron M; Kendall Debra A; Von Heijne Gunnar; Chin Chen-Ni
Membrane assembly of the cannabinoid receptor 1: impact of a long N-terminal tail.
Molecular pharmacology 2003;64(3):570-7.
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2003: Juncker Agnieszka S; Willenbrock Hanni; Von Heijne Gunnar; Brunak Søren; Nielsen Henrik; Krogh Anders
Prediction of lipoprotein signal peptides in Gram-negative bacteria.
Protein science : a publication of the Protein Society 2003;12(8):1652-62.
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2003: Nilsson IngMarie; Johnson Arthur E; von Heijne Gunnar
How hydrophobic is alanine?
The Journal of biological chemistry 2003;278(32):29389-93.
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2003: Emanuelsson Olof; Elofsson Arne; von Heijne Gunnar; Cristóbal Susana
In silico prediction of the peroxisomal proteome in fungi, plants and animals.
Journal of molecular biology 2003;330(2):443-56.
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2003: Kim Hyun; Yan Qi; Von Heijne Gunnar; Caputo Gregory A; Lennarz William J
Determination of the membrane topology of Ost4p and its subunit interactions in the oligosaccharyltransferase complex in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7460-4.
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2003: Nilsson IngMarie; Kelleher Daniel J; Miao Yiwei; Shao Yuanlong; Kreibich Gert; Gilmore Reid; von Heijne Gunnar; Johnson Arthur E
Photocross-linking of nascent chains to the STT3 subunit of the oligosaccharyltransferase complex.
The Journal of cell biology 2003;161(4):715-25.
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2003: Lundin Marika; Monné Magnus; Widell Anders; Von Heijne Gunnar; Persson Mats A A
Topology of the membrane-associated hepatitis C virus protein NS4B.
Journal of virology 2003;77(9):5428-38.
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2003: Melén Karin; Krogh Anders; von Heijne Gunnar
Reliability measures for membrane protein topology prediction algorithms.
Journal of molecular biology 2003;327(3):735-44.
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2003: Kim Hyun; Melén Karin; von Heijne Gunnar
Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions.
The Journal of biological chemistry 2003;278(12):10208-13.
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2003: Hessa Tara; Monné Magnus; von Heijne Gunnar
Stop-transfer efficiency of marginally hydrophobic segments depends on the length of the carboxy-terminal tail.
EMBO reports 2003;4(2):178-83.
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2003: Von Heijne Gunnar
Membrane protein assembly in vivo.
Advances in protein chemistry 2003;63():1-18.
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2002: Nilsson Johan; Persson Bengt; Von Heijne Gunnar
Prediction of partial membrane protein topologies using a consensus approach.
Protein science : a publication of the Protein Society 2002;11(12):2974-80.
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2002: Vilar Marçal; Saurí Ana; Monné Magnus; Marcos José F; von Heijne Gunnar; Pérez-Payá Enrique; Mingarro Ismael
Insertion and topology of a plant viral movement protein in the endoplasmic reticulum membrane.
The Journal of biological chemistry 2002;277(26):23447-52.
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2002: Chin Chen-Ni; von Heijne Gunnar; de Gier Jan-Willem L
Membrane proteins: shaping up.
Trends in biochemical sciences 2002;27(5):231-4.
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2002: Nilsson IngMarie; Johnson Arthur E; von Heijne Gunnar
Cleavage of a tail-anchored protein by signal peptidase.
FEBS letters 2002;516(1-3):106-8.
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2002: Drew David; Sjöstrand Dan; Nilsson Johan; Urbig Thomas; Chin Chen-ni; de Gier Jan-Willem; von Heijne Gunnar
Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2690-5.
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2002: Hedman Maria; Deloof Hans; Von Heijne Gunnar; Elofsson Arne
Improved detection of homologous membrane proteins by inclusion of information from topology predictions.
Protein science : a publication of the Protein Society 2002;11(3):652-8.
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2002: Peltier Jean-Benoît; Emanuelsson Olof; Kalume Dário E; Ytterberg Jimmy; Friso Giulia; Rudella Andrea; Liberles David A; Söderberg Linda; Roepstorff Peter; von Heijne Gunnar; van Wijk Klaas J
Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction.
The Plant cell 2002;14(1):211-36.
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2001: Emanuelsson O; von Heijne G
Prediction of organellar targeting signals.
Biochimica et biophysica acta 2001;1541(1-2):114-9.
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2001: Hermansson M; Monné M; von Heijne G
Formation of helical hairpins during membrane protein integration into the endoplasmic reticulum membrane. Role of the N and C-terminal flanking regions.
Journal of molecular biology 2001;313(5):1171-9.
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2001: Nilsson I; Ohvo-Rekilä H; Slotte J P; Johnson A E; von Heijne G
Inhibition of protein translocation across the endoplasmic reticulum membrane by sterols.
The Journal of biological chemistry 2001;276(45):41748-54.
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2001: Drew D E; von Heijne G; Nordlund P; de Gier J W
Green fluorescent protein as an indicator to monitor membrane protein overexpression in Escherichia coli.
FEBS letters 2001;507(2):220-4.
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2001: Sääf A; Baars L; von Heijne G
The internal repeats in the Na+/Ca2+ exchanger-related Escherichia coli protein YrbG have opposite membrane topologies.
The Journal of biological chemistry 2001;276(22):18905-7.
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2001: Monné M; von Heijne G
Effects of 'hydrophobic mismatch' on the location of transmembrane helices in the ER membrane.
FEBS letters 2001;496(2-3):96-100.
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2001: Krogh A; Larsson B; von Heijne G; Sonnhammer E L
Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Journal of molecular biology 2001;305(3):567-80.
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2001: Emanuelsson O; von Heijne G; Schneider G
Analysis and prediction of mitochondrial targeting peptides.
Methods in cell biology 2001;65():175-87.
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2000: Nilsson J; Persson B; von Heijne G
Consensus predictions of membrane protein topology.
FEBS letters 2000;486(3):267-9.
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2000: Chin C N; von Heijne G
Charge pair interactions in a model transmembrane helix in the ER membrane.
Journal of molecular biology 2000;303(1):1-5.
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2000: Sääf A; Hermansson M; von Heijne G
Formation of cytoplasmic turns between two closely spaced transmembrane helices during membrane protein integration into the ER membrane.
Journal of molecular biology 2000;301(1):191-7.
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2000: Emanuelsson O; Nielsen H; Brunak S; von Heijne G
Predicting subcellular localization of proteins based on their N-terminal amino acid sequence.
Journal of molecular biology 2000;300(4):1005-16.
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2000: Nilsson I; von Heijne G
Glycosylation efficiency of Asn-Xaa-Thr sequons depends both on the distance from the C terminus and on the presence of a downstream transmembrane segment.
The Journal of biological chemistry 2000;275(23):17338-43.
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2000: Nilsson I; Witt S; Kiefer H; Mingarro I; von Heijne G
Distant downstream sequence determinants can control N-tail translocation during protein insertion into the endoplasmic reticulum membrane.
The Journal of biological chemistry 2000;275(9):6207-13.
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2000: Scotti P A; Urbanus M L; Brunner J; de Gier J W; von Heijne G; van der Does C; Driessen A J; Oudega B; Luirink J
YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase.
The EMBO journal 2000;19(4):542-9.
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2000: Mingarro I; Nilsson I; Whitley P; von Heijne G
Different conformations of nascent polypeptides during translocation across the ER membrane.
BMC cell biology 2000;1():3.
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1999: Armulik A; Nilsson I; von Heijne G; Johansson S
Determination of the border between the transmembrane and cytoplasmic domains of human integrin subunits.
The Journal of biological chemistry 1999;274(52):37030-4.
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1999: Monné M; Nilsson I; Elofsson A; von Heijne G
Turns in transmembrane helices: determination of the minimal length of a "helical hairpin" and derivation of a fine-grained turn propensity scale.
Journal of molecular biology 1999;293(4):807-14.
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1999: von Heijne G
A Day in the Life of Dr K. or How I Learned to Stop Worrying and Love Lysozyme: a tragedy in six acts.
Journal of molecular biology 1999;293(2):367-79.
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1999: Monné M; Gafvelin G; Nilsson R; von Heijne G
N-tail translocation in a eukaryotic polytopic membrane protein: synergy between neighboring transmembrane segments.
European journal of biochemistry / FEBS 1999;263(1):264-9.
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1999: Braun P; von Heijne G
The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane.
Biochemistry 1999;38(30):9778-82.
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1999: Sääf A; Johansson M; Wallin E; von Heijne G
Divergent evolution of membrane protein topology: the Escherichia coli RnfA and RnfE homologues.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8540-4.
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1999: Cristóbal S; Scotti P; Luirink J; von Heijne G; de Gier J W
The signal recognition particle-targeting pathway does not necessarily deliver proteins to the sec-translocase in Escherichia coli.
The Journal of biological chemistry 1999;274(29):20068-70.
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1999: Cristóbal S; de Gier J W; Nielsen H; von Heijne G
Competition between Sec- and TAT-dependent protein translocation in Escherichia coli.
The EMBO journal 1999;18(11):2982-90.
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1999: Emanuelsson O; Nielsen H; von Heijne G
ChloroP, a neural network-based method for predicting chloroplast transit peptides and their cleavage sites.
Protein science : a publication of the Protein Society 1999;8(5):978-84.
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1999: Monné M; Hermansson M; von Heijne G
A turn propensity scale for transmembrane helices.
Journal of molecular biology 1999;288(1):141-5.
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1999: Nielsen H; Brunak S; von Heijne G
Machine learning approaches for the prediction of signal peptides and other protein sorting signals.
Protein engineering 1999;12(1):3-9.
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1998: de Gier J W; Scotti P A; Sääf A; Valent Q A; Kuhn A; Luirink J; von Heijne G
Differential use of the signal recognition particle translocase targeting pathway for inner membrane protein assembly in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14646-51.
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1998: Nilsson I; von Heijne G
Breaking the camel's back: proline-induced turns in a model transmembrane helix.
Journal of molecular biology 1998;284(4):1185-9.
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1998: Monné M; Nilsson I; Johansson M; Elmhed N; von Heijne G
Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix.
Journal of molecular biology 1998;284(4):1177-83.
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1998: Nilsson I; Sääf A; Whitley P; Gafvelin G; Waller C; von Heijne G
Proline-induced disruption of a transmembrane alpha-helix in its natural environment.
Journal of molecular biology 1998;284(4):1165-75.
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1998: Sääf A; Monné M; de Gier J W; von Heijne G
Membrane topology of the 60-kDa Oxa1p homologue from Escherichia coli.
The Journal of biological chemistry 1998;273(46):30415-8.
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1998: Seshadri K; Garemyr R; Wallin E; von Heijne G; Elofsson A
Architecture of beta-barrel membrane proteins: analysis of trimeric porins.
Protein science : a publication of the Protein Society 1998;7(9):2026-32.
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1998: Valent Q A; Scotti P A; High S; de Gier J W; von Heijne G; Lentzen G; Wintermeyer W; Oudega B; Luirink J
The Escherichia coli SRP and SecB targeting pathways converge at the translocon.
The EMBO journal 1998;17(9):2504-12.
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1998: Wallin E; von Heijne G
Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms.
Protein science : a publication of the Protein Society 1998;7(4):1029-38.
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1998: Sääf A; Wallin E; von Heijne G
Stop-transfer function of pseudo-random amino acid segments during translocation across prokaryotic and eukaryotic membranes.
European journal of biochemistry / FEBS 1998;251(3):821-9.
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1997: Nielsen H; Engelbrecht J; Brunak S; von Heijne G
A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites.
International journal of neural systems 1997;8(5-6):581-99.
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1997: Mingarro I; von Heijne G; Whitley P
Membrane-protein engineering.
Trends in biotechnology 1997;15(10):432-7.
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1997: Mingarro I; Elofsson A; von Heijne G
Helix-helix packing in a membrane-like environment.
Journal of molecular biology 1997;272(4):633-41.
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1997: Valent Q A; de Gier J W; von Heijne G; Kendall D A; ten Hagen-Jongman C M; Oudega B; Luirink J
Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor.
Molecular microbiology 1997;25(1):53-64.
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1997: Cserzö M; Wallin E; Simon I; von Heijne G; Elofsson A
Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method.
Protein engineering 1997;10(6):673-6.
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1997: De Gier J W; Valent Q A; Von Heijne G; Luirink J
The E. coli SRP: preferences of a targeting factor.
FEBS letters 1997;408(1):1-4.
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1997: von Heijne G
Getting greasy: how transmembrane polypeptide segments integrate into the lipid bilayer.
Molecular microbiology 1997;24(2):249-53.
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1997: Wallin E; Tsukihara T; Yoshikawa S; von Heijne G; Elofsson A
Architecture of helix bundle membrane proteins: an analysis of cytochrome c oxidase from bovine mitochondria.
Protein science : a publication of the Protein Society 1997;6(4):808-15.
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1997: Gafvelin G; Sakaguchi M; Andersson H; von Heijne G
Topological rules for membrane protein assembly in eukaryotic cells.
The Journal of biological chemistry 1997;272(10):6119-27.
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1997: Nielsen H; Engelbrecht J; Brunak S; von Heijne G
Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites.
Protein engineering 1997;10(1):1-6.
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1996: de Gier J W; Mansournia P; Valent Q A; Phillips G J; Luirink J; von Heijne G
Assembly of a cytoplasmic membrane protein in Escherichia coli is dependent on the signal recognition particle.
FEBS letters 1996;399(3):307-9.
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1996: Kiefer H; Krieger J; Olszewski J D; Von Heijne G; Prestwich G D; Breer H
Expression of an olfactory receptor in Escherichia coli: purification, reconstitution, and ligand binding.
Biochemistry 1996;35(50):16077-84.
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1996: Andersson H; Nilsson I; von Heijne G
Calnexin can interact with N-linked glycans located close to the endoplasmic reticulum membrane.
FEBS letters 1996;397(2-3):321-4.
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1996: Johansson M; von Heijne G
Membrane topology of Kch, a putative K+ channel from Escherichia coli.
The Journal of biological chemistry 1996;271(42):25912-5.
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1996: Mingarro I; Whitley P; Lemmon M A; von Heijne G
Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix: a rapid way to map helix-helix interactions in integral membrane proteins.
Protein science : a publication of the Protein Society 1996;5(7):1339-41.
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1996: Whitley P; Grahn E; Kutay U; Rapoport T A; von Heijne G
A 12-residue-long polyleucine tail is sufficient to anchor synaptobrevin to the endoplasmic reticulum membrane.
The Journal of biological chemistry 1996;271(13):7583-6.
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1996: Whitley P; Nilsson I M; von Heijne G
A nascent secretory protein may traverse the ribosome/endoplasmic reticulum translocase complex as an extended chain.
The Journal of biological chemistry 1996;271(11):6241-4.
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1996: Nielsen H; Engelbrecht J; von Heijne G; Brunak S
Defining a similarity threshold for a functional protein sequence pattern: the signal peptide cleavage site.
Proteins 1996;24(2):165-77.
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1995: Whitley P; Gafvelin G; von Heijne G
SecA-independent translocation of the periplasmic N-terminal tail of an Escherichia coli inner membrane protein. Position-specific effects on translocation of positively charged residues and construction of a protein with a C-terminal translocation signal.
The Journal of biological chemistry 1995;270(50):29831-5.
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1995: Whitley P; Sääf A; Gafvelin G; Johansson M; Wallin E; von Heijne G
Membrane protein anchors and polytopic determinants.
Biochemical Society transactions 1995;23(4):965-7.
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1995: Wallin E; von Heijne G
Properties of N-terminal tails in G-protein coupled receptors: a statistical study.
Protein engineering 1995;8(7):693-8.
-
1995: Sääf A; Andersson H; Gafvelin G; von Heijne G
SecA-dependence of the translocation of a large periplasmic loop in the Escherichia coli MalF inner membrane protein is a function of sequence context.
Molecular membrane biology 1995;12(2):209-15.
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1994: Whitley P; Nilsson I; von Heijne G
De novo design of integral membrane proteins.
Nature structural biology 1994;1(12):858-62.
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1994: von Heijne G
Sec-independent protein insertion into the inner E. coli membrane. A phenomenon in search of an explanation.
FEBS letters 1994;346(1):69-72.
-
1994: Andersson H; von Heijne G
Membrane protein topology: effects of delta mu H+ on the translocation of charged residues explain the 'positive inside' rule.
The EMBO journal 1994;13(10):2267-72.
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1994: Gafvelin G; von Heijne G
Topological "frustration" in multispanning E. coli inner membrane proteins.
Cell 1994;77(3):401-12.
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1993: Whitley P; Nilsson L; von Heijne G
Three-dimensional model for the membrane domain of Escherichia coli leader peptidase based on disulfide mapping.
Biochemistry 1993;32(33):8534-9.
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