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Steven Bozinovski

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Stavros Selemidis; Huei Jiunn Seow; Christopher G Sobey; Antony Vinh; Steven Bozinovski; Brad R S Broughton; Grant R Drummond; Ross Vlahos
Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress.
Selcuk Yatmaz; Zi Xin Wong; Gary P Anderson; Steven Bozinovski; Peter J Crack; Rosa C Gualano; Stavros Selemidis; Huei Jiunn Seow; John Stambas; Ross Vlahos
Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation.
Robert J J O'Donoghue; Cecilia M Prêle; Carl D Richards; Stefan Rose-John; Philip Stumbles; Stefan Thiem; Ross Vlahos; Bo Wang; Hong Jian Zhu; Gary P Anderson; Steven Bozinovski; Matthias R Ernst; Andrew G Jarnicki; Jessica Jones; Darryl A Knight; Hui Ling Lau; Geoffrey J Laurent; Robin J McAnulty; Brent S McKenzie; Steven E Mutsaers
Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis.

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All Publications

2013: Stavros Selemidis; Huei Jiunn Seow; Christopher G Sobey; Antony Vinh; Steven Bozinovski; Brad R S Broughton; Grant R Drummond; Ross Vlahos
Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress.
PloS one 2013;8(4):e60792.
2013: Selcuk Yatmaz; Zi Xin Wong; Gary P Anderson; Steven Bozinovski; Peter J Crack; Rosa C Gualano; Stavros Selemidis; Huei Jiunn Seow; John Stambas; Ross Vlahos
Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation.
American journal of respiratory cell and molecular biology 2013;48(1):17-26.
2012: Robert J J O'Donoghue; Cecilia M Prêle; Carl D Richards; Stefan Rose-John; Philip Stumbles; Stefan Thiem; Ross Vlahos; Bo Wang; Hong Jian Zhu; Gary P Anderson; Steven Bozinovski; Matthias R Ernst; Andrew G Jarnicki; Jessica Jones; Darryl A Knight; Hui Ling Lau; Geoffrey J Laurent; Robin J McAnulty; Brent S McKenzie; Steven E Mutsaers
Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis.
EMBO molecular medicine 2012;4(9):939-51.
2012: Saleela M Ruwanpura; Ross Vlahos; Gary P Anderson; Philip G Bardin; Steven Bozinovski; Jessica Jones; Anthony Longano; Louise McLeod; Alistair Miller; Georg Ramm; Brendan J Jenkins
Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice.
American journal of physiology. Lung cellular and molecular physiology 2012;302(7):L627-39.
2012: Steven Bozinovski; Anastasia Hutchinson; Louis B Irving; Bruce D Levy; Jonathan L McQualter; Anne-Sophie Merritt; Michelle Thompson; Mohib Uddin; Ross Vlahos; Peter A B Wark; Gary P Anderson
Serum amyloid A opposes lipoxin A₄ to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(3):935-40.
2012: Ross Vlahos; Peter A B Wark; Gary P Anderson; Steven Bozinovski
Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD.
PloS one 2012;7(3):e33277.
2012: Steven Bozinovski; Peter J Crack; Huei Jiunn Seow; Gary P Anderson; Ross Vlahos
Glutathione peroxidase-1 primes pro-inflammatory cytokine production after LPS challenge in vivo.
PloS one 2012;7(3):e33172.
2011: Saleela M Ruwanpura; Ross Vlahos; Jessica Jones; Louise McLeod; Alistair Miller; Gary P Anderson; Jane Armes; Philip G Bardin; Steven Bozinovski; Matthias Ernst; Brendan J Jenkins
Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.
American journal of respiratory cell and molecular biology 2011;45(4):720-30.
2011: Steven Bozinovski; Lin Chin Lah; Ashley Mansell; Huei Jiunn Seow; Ross Vlahos; Yilin Zhang; Gary P Anderson
Carbonylation caused by cigarette smoke extract is associated with defective macrophage immunity.
American journal of respiratory cell and molecular biology 2011;45(2):229-36.
2011: Ross Vlahos; John Stambas; Steven Bozinovski; Brad R S Broughton; Grant R Drummond; Stavros Selemidis
Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation.
PLoS pathogens 2011;7(2):e1001271.
2010: Chi Duong; Huei Jiunn Seow; Steven Bozinovski; Peter J Crack; Gary P Anderson; Ross Vlahos
Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice.
American journal of physiology. Lung cellular and molecular physiology 2010;299(3):L425-33.
2010: Gerdt C Riise; Petrea Ericson; Steven Bozinovski; Shigemi Yoshihara; Gary P Anderson; Anders Lindén
Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2010;29(7):800-7.
2010: Ross Vlahos; Steven Bozinovski; Sheau Pyng Jamie Chan; Stefan Ivanov; Anders Lindén; John A Hamilton; Gary P Anderson
Neutralizing granulocyte/macrophage colony-stimulating factor inhibits cigarette smoke-induced lung inflammation.
American journal of respiratory and critical care medicine 2010;182(1):34-40.
2010: Anastasia F Hutchinson; Jim Black; Michelle A Thompson; Steven Bozinovski; Caroline A Brand; David M Smallwood; Louis B Irving; Gary P Anderson
Identifying viral infections in vaccinated Chronic Obstructive Pulmonary Disease (COPD) patients using clinical features and inflammatory markers.
Influenza and other respiratory viruses 2010;4(1):33-9.
2009: Olof Prause; Apostolos Bossios; Elin Silverpil; Stefan Ivanov; Steven Bozinovski; Ross Vlahos; Margareta Sjöstrand; Gary P Anderson; Anders Lindén
IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo--effects of anti-inflammatory pharmacotherapy.
Pulmonary pharmacology & therapeutics 2009;22(3):199-207.
2008: Connie H Y Wong; Steven Bozinovski; Paul J Hertzog; Michael J Hickey; Peter J Crack
Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion.
Journal of neurochemistry 2008;107(1):241-52.
2008: P Glader; B Eldh; Steven Bozinovski; Kristina Andelid; Margareta Sjöstrand; Carina Malmhäll; Gary P Anderson; Gerdt C Riise; Ingemar Qvarfordt; Anders Lindén
Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space.
The European respiratory journal 2008;32(3):644-50.
2008: Kenneth Liu; Gary P Anderson; Steven Bozinovski
DNA vector augments inflammation in epithelial cells via EGFR-dependent regulation of TLR4 and TLR2.
American journal of respiratory cell and molecular biology 2008;39(3):305-11.
2008: Kenneth Liu; Rosa C Gualano; Margaret L Hibbs; Gary P Anderson; Steven Bozinovski
Epidermal growth factor receptor signaling to Erk1/2 and STATs control the intensity of the epithelial inflammatory responses to rhinovirus infection.
The Journal of biological chemistry 2008;283(15):9977-85.
2008: Steven Bozinovski; Anastasia Hutchinson; Michelle Thompson; Lochlan Macgregor; James Black; Eleni Giannakis; Anne-Sophie Karlsson; Roger Silvestrini; David Smallwood; Ross Vlahos; Louis B Irving; Gary P Anderson
Serum amyloid a is a biomarker of acute exacerbations of chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2008;177(3):269-78.
2007: Anastasia F Hutchinson; Anil K Ghimire; Michelle A Thompson; James F Black; Caroline A Brand; Adrian J Lowe; David M Smallwood; Ross Vlahos; Steven Bozinovski; Graham V Brown; Gary P Anderson; Louis B Irving
A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD.
Respiratory medicine 2007;101(12):2472-81.
2007: Stefan Ivanov; Steven Bozinovski; Apostolos Bossios; Hadi Valadi; Ross Vlahos; Carina Malmhäll; Margareta Sjöstrand; Jay K Kolls; Gary P Anderson; Anders Lindén
Functional relevance of the IL-23-IL-17 axis in lungs in vivo.
American journal of respiratory cell and molecular biology 2007;36(4):442-51.
2007: Hui Chen; Michelle J Hansen; Jessica E Jones; Ross Vlahos; Steven Bozinovski; Gary P Anderson; Margaret J Morris
Regulation of hypothalamic NPY by diet and smoking.
Peptides 2007;28(2):384-9.
2006: Ross Vlahos; Steven Bozinovski; John A Hamilton; Gary P Anderson
Therapeutic potential of treating chronic obstructive pulmonary disease (COPD) by neutralising granulocyte macrophage-colony stimulating factor (GM-CSF).
Pharmacology & therapeutics 2006;112(1):106-15.
2006: Hui Chen; Michelle J Hansen; Jessica E Jones; Ross Vlahos; Steven Bozinovski; Gary P Anderson; Margaret J Morris
Cigarette smoke exposure reprograms the hypothalamic neuropeptide Y axis to promote weight loss.
American journal of respiratory and critical care medicine 2006;173(11):1248-54.
2006: Ross Vlahos; Steven Bozinovski; Jessica E Jones; J Powell; J Gras; A Lilja; Michelle J Hansen; Rosa C Gualano; L Irving; Gary P Anderson
Differential protease, innate immunity, and NF-kappaB induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice.
American journal of physiology. Lung cellular and molecular physiology 2006;290(5):L931-45.
2006: Steven Bozinovski; Ross Vlahos; Michelle Hansen; Ken Liu; Gary P Anderson
Akt in the pathogenesis of COPD.
International journal of chronic obstructive pulmonary disease 2006;1(1):31-8.
2006: Ross Vlahos; Steven Bozinovski; Rosa C Gualano; Matthias Ernst; Gary P Anderson
Modelling COPD in mice.
Pulmonary pharmacology & therapeutics 2006;19(1):12-7.
2006: Michelle J Hansen; Rosa C Gualano; Steven Bozinovski; Ross Vlahos; Gary P Anderson
Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease).
Pharmacology & therapeutics 2006;109(1-2):162-72.
2005: Hui Chen; Ross Vlahos; Steven Bozinovski; Jessica Jones; Gary P Anderson; Margaret J Morris
Effect of short-term cigarette smoke exposure on body weight, appetite and brain neuropeptide Y in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(4):713-9.
2005: Steven Bozinovski; Maddalena Cross; Ross Vlahos; Jessica E Jones; Kenneth Hsuu; Philippe A Tessier; Eric C Reynolds; David A Hume; John A Hamilton; Carolyn L Geczy; Gary P Anderson
S100A8 chemotactic protein is abundantly increased, but only a minor contributor to LPS-induced, steroid resistant neutrophilic lung inflammation in vivo.
Journal of proteome research 2005;4(1):136-45.
2004: Martti Laan; Steven Bozinovski; Gary P Anderson
Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):4164-70.
2004: Olof Prause; Steven Bozinovski; Gary P Anderson; Anders Lindén
Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways.
Thorax 2004;59(4):313-7.
2004: Steven Bozinovski; Jessica Jones; Sarah-Jane E Beavitt; Andrew D Cook; John A Hamilton; Gary P Anderson
Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4.
American journal of physiology. Lung cellular and molecular physiology 2004;286(4):L877-85.
2004: Brendan J Jenkins; Dianne Grail; Melissa Inglese; Cathy Quilici; Steven Bozinovski; Peter Wong; Matthias Ernst
Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.
Molecular and cellular biology 2004;24(4):1453-63.
2003: Gary P Anderson; Steven Bozinovski
Acquired somatic mutations in the molecular pathogenesis of COPD.
Trends in pharmacological sciences 2003;24(2):71-6.
2002: Steven Bozinovski; Jessica E Jones; Ross Vlahos; John A Hamilton; Gary P Anderson
Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo.
The Journal of biological chemistry 2002;277(45):42808-14.
2002: Matthias Ernst; Melissa Inglese; Glen M Scholz; Kenneth W Harder; Fiona J Clay; Steven Bozinovski; Paul Waring; Rima Darwiche; Tom Kay; Peter Sly; Rachel Collins; Debra Turner; Margaret L Hibbs; Gary P Anderson; Ashley R Dunn
Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response.
The Journal of experimental medicine 2002;196(5):589-604.
2002: Steven Bozinovski; Briony E Cristiano; Nelly Marmy-Conus; Richard B Pearson
The synthetic peptide RPRAATF allows specific assay of Akt activity in cell lysates.
Analytical biochemistry 2002;305(1):32-9.
1999: Belinda J Michell; J E Griffiths; Kenneth I Mitchelhill; I Rodriguez-Crespo; Tony Tiganis; Steven Bozinovski; P R de Montellano; Bruce E Kemp; Richard B Pearson
The Akt kinase signals directly to endothelial nitric oxide synthase.
Current biology : CB 1999;9(15):845-8.