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John Aitken

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Anatomy

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Co-Publications
Name
25
Baker, Mark
17
mclaughlin, eileen
11
Nixon, Brett
10
De Iuliis, Geoffry
9
Hetherington, Louise
9
Roman, Shaun
6
Lin, Minjie
6
Curry, Benjamin
5
Koppers, Adam
5
Jones, Russell
4
Holt, Janet
4
Ecroyd, Heath
4
Griffith, Renate
3
Krutskikh, Anton
3
Asquith, Kelly

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Publications

TOP 3
Baker Mark A; Hetherington Louise; Curry Benjamin; Aitken R John
Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa; its implications during capacitation.
De Iuliis Geoffry N; Thomson Laura K; Mitchell Lisa A; Finnie Jane M; Koppers Adam J; Hedges Andrew; Nixon Brett; Aitken R John
DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress.
Aitken R John
Gpx5 protects the family jewels.

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All Publications

2009: Baker Mark A; Hetherington Louise; Curry Benjamin; Aitken R John
Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa; its implications during capacitation.
Developmental biology 2009;333(1):57-66.
2009: De Iuliis Geoffry N; Thomson Laura K; Mitchell Lisa A; Finnie Jane M; Koppers Adam J; Hedges Andrew; Nixon Brett; Aitken R John
DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress.
Biology of reproduction 2009;81(3):517-24.
2009: Aitken R John
Gpx5 protects the family jewels.
The Journal of clinical investigation 2009;119(7):1849-51.
2009: Hughes Louise M; Griffith Renate; Carey Alison; Butler Trent; Donne Scott W; Beagley Ken W; Aitken R John
The spermostatic and microbicidal actions of quinones and maleimides: toward a dual-purpose contraceptive agent.
Molecular pharmacology 2009;76(1):113-24.
2009: Aitken R John; De Iuliis Geoffry N; McLachlan Robert I
Biological and clinical significance of DNA damage in the male germ line.
International journal of andrology 2009;32(1):46-56.
2009: Nixon Brett; Bielanowicz Amanda; McLaughlin Eileen A; Tanphaichitr Nongnuj; Ensslin Michael A; Aitken R John
Composition and significance of detergent resistant membranes in mouse spermatozoa.
Journal of cellular physiology 2009;218(1):122-34.
2009: De Iuliis Geoffry N; Newey Rhiannon J; King Bruce V; Aitken R John
Mobile phone radiation induces reactive oxygen species production and DNA damage in human spermatozoa in vitro.
PloS one 2009;4(7):e6446.
2008: Aitken R John; Roman Shaun D
Antioxidant systems and oxidative stress in the testes.
Oxidative medicine and cellular longevity 2008;1(1):15-24.
2008: Aitken R John; Hughes Louise M; Griffith Renate; Baker Mark A
Bridging the gap between male and female fertility control; contraception-on-demand.
Contraception 2008;78(4 Suppl):S28-35.
2008: Koppers Adam J; De Iuliis Geoffry N; Finnie Jane M; McLaughlin Eileen A; Aitken R John
Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa.
The Journal of clinical endocrinology and metabolism 2008;93(8):3199-207.
2008: Baker Mark A; Hetherington Louise; Reeves Gabi; Müller Jörg; Aitken R John
The rat sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification.
Proteomics 2008;8(11):2312-21.
2008: Walsh Andrew; Whelan Dean; Bielanowicz Amanda; Skinner Brooke; Aitken R John; O'Bryan Moira K; Nixon Brett
Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse.
Biology of reproduction 2008;78(6):983-93.
2008: Aitken R John; Baker Mark A
The role of proteomics in understanding sperm cell biology.
International journal of andrology 2008;31(3):295-302.
2008: Bennetts L E; De Iuliis G N; Nixon B; Kime M; Zelski K; McVicar C M; Lewis S E; Aitken R J
Impact of estrogenic compounds on DNA integrity in human spermatozoa: evidence for cross-linking and redox cycling activities.
Mutation research 2008;641(1-2):1-11.
2008: Aitken R John; Baker Mark A; Doncel Gustavo F; Matzuk Martin M; Mauck Christine K; Harper Michael J K
As the world grows: contraception in the 21st century.
The Journal of clinical investigation 2008;118(4):1330-43.
2008: Baker Mark A; Hetherington Louise; Reeves Gabi M; Aitken R John
The mouse sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification.
Proteomics 2008;8(8):1720-30.
2008: Mitchell Lisa A; Nixon Brett; Baker Mark A; Aitken R John
Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa.
Molecular human reproduction 2008;14(4):235-43.
2008: Aitken R John; Roman Shaun D
Antioxidant systems and oxidative stress in the testes.
Advances in experimental medicine and biology 2008;636():154-71.
2007: Hughes Louise; Wingate Jordana; Griffith Renate; Aitken R John
Modelling and measuring redox cycling and cytotoxicity of quinones.
Drug metabolism letters 2007;1(4):245-53.
2007: Mitchell L A; Nixon B; Aitken R J
Analysis of chaperone proteins associated with human spermatozoa during capacitation.
Molecular human reproduction 2007;13(9):605-13.
2007: Aitken R John; Nixon Brett; Lin Minjie; Koppers Adam J; Lee Yun H; Baker Mark A
Proteomic changes in mammalian spermatozoa during epididymal maturation.
Asian journal of andrology 2007;9(4):554-64.
2007: Nixon B; Aitken R J; McLaughlin E A
New insights into the molecular mechanisms of sperm-egg interaction.
Cellular and molecular life sciences : CMLS 2007;64(14):1805-23.
2007: Aitken R John; De Iuliis Geoffry N
Origins and consequences of DNA damage in male germ cells.
Reproductive biomedicine online 2007;14(6):727-33.
2007: Aitken R John; Wingate Jordana K; De Iuliis Geoffry N; McLaughlin Eileen A
Analysis of lipid peroxidation in human spermatozoa using BODIPY C11.
Molecular human reproduction 2007;13(4):203-11.
2007: Ainsworth C; Nixon B; Jansen R P S; Aitken R J
First recorded pregnancy and normal birth after ICSI using electrophoretically isolated spermatozoa.
Human reproduction (Oxford, England) 2007;22(1):197-200.
2007: Aitken R John; De Iuliis Geoffry N
Value of DNA integrity assays for fertility evaluation.
Society of Reproduction and Fertility supplement 2007;65():81-92.
2007: Aitken R J; McLaughlin E A
Molecular mechanisms of sperm capacitation: progesterone-induced secondary calcium oscillations reflect the attainment of a capacitated state.
Society of Reproduction and Fertility supplement 2007;63():273-93.
2007: Hughes Louise M; Griffith Renate; Aitken R J
The search for a topical dual action spermicide/microbicide.
Current medicinal chemistry 2007;14(7):775-86.
2006: Aitken R John; Wingate Jordana K; De Iuliis Geoffry N; Koppers Adam J; McLaughlin Eileen A
Cis-unsaturated fatty acids stimulate reactive oxygen species generation and lipid peroxidation in human spermatozoa.
The Journal of clinical endocrinology and metabolism 2006;91(10):4154-63.
2006: Lin Minjie; Lee Yun Hwa; Xu Weian; Baker Mark A; Aitken R John
Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse.
Biology of reproduction 2006;75(4):588-97.
2006: Baker Mark A; Hetherington Louise; Aitken R John
Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa.
Journal of cell science 2006;119(Pt 15):3182-92.
2006: Holt Janet E; Jackson Andrew; Roman Shaun D; Aitken R John; Koopman Peter; McLaughlin Eileen A
CXCR4/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary.
Developmental biology 2006;293(2):449-60.
2006: De Iuliis Geoffry N; Wingate Jordana K; Koppers Adam J; McLaughlin Eileen A; Aitken R John
Definitive evidence for the nonmitochondrial production of superoxide anion by human spermatozoa.
The Journal of clinical endocrinology and metabolism 2006;91(5):1968-75.
2006: Aitken R John; Baker Mark A
Oxidative stress, sperm survival and fertility control.
Molecular and cellular endocrinology 2006;250(1-2):66-9.
2006: Holt Janet E; Roman Shaun D; Aitken R John; McLaughlin Eileen A
Identification and characterization of a novel Mt-retrotransposon highly represented in the female mouse germline.
Genomics 2006;87(4):490-9.
2006: Aitken R J
Sperm function tests and fertility.
International journal of andrology 2006;29(1):69-75; discussion 105-8.
2006: Curry Benjamin J; Holt Janet E; McLaughlin Eileen A; Aitken R John
Characterization of structure and expression of the Dzip1 gene in the rat and mouse.
Genomics 2006;87(2):275-85.
2006: Nixon Brett; MacIntyre David A; Mitchell Lisa A; Gibbs Gerard M; O'Bryan Moira; Aitken R John
The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors.
Biology of reproduction 2006;74(2):275-87.
2006: Gasanov Uta; Koina Craig; Beagley Kenneth W; Aitken R John; Hansbro Philip M
Identification of the insulin-like growth factor II receptor as a novel receptor for binding and invasion by Listeria monocytogenes.
Infection and immunity 2006;74(1):566-77.
2005: Nixon Brett; Paul Jonathan W; Spiller Cassy M; Attwell-Heap Abigail G; Ashman Leonie K; Aitken R John
Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa.
Journal of cell science 2005;118(Pt 20):4865-77.
2005: Baleato Rosa M; Aitken R John; Roman Shaun D
Vitamin A regulation of BMP4 expression in the male germ line.
Developmental biology 2005;286(1):78-90.
2005: Baker Mark A; Krutskikh Anton; Curry Benjamin J; Hetherington Louise; Aitken R John
Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa.
Biology of reproduction 2005;73(2):334-42.
2005: Ainsworth C; Nixon B; Aitken R J
Development of a novel electrophoretic system for the isolation of human spermatozoa.
Human reproduction (Oxford, England) 2005;20(8):2261-70.
2005: Aitken R J; Bennetts L E; Sawyer D; Wiklendt A M; King B V
Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline.
International journal of andrology 2005;28(3):171-9.
2005: Bennetts Liga E; Aitken R John
A comparative study of oxidative DNA damage in mammalian spermatozoa.
Molecular reproduction and development 2005;71(1):77-87.
2005: Baker Mark A; Witherdin Roxanne; Hetherington Louise; Cunningham-Smith Kelly; Aitken R John
Identification of post-translational modifications that occur during sperm maturation using difference in two-dimensional gel electrophoresis.
Proteomics 2005;5(4):1003-12.
2005: Asquith Kelly L; Harman Amanda J; McLaughlin Eileen A; Nixon Brett; Aitken R John
Localization and significance of molecular chaperones, heat shock protein 1, and tumor rejection antigen gp96 in the male reproductive tract and during capacitation and acrosome reaction.
Biology of reproduction 2005;72(2):328-37.
2005: Baker Mark A; Aitken R John
Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility.
Reproductive biology and endocrinology : RB&E 2005;3():67.
2004: Aitken R John; Koopman Peter; Lewis Sheena E M
Seeds of concern.
Nature 2004;432(7013):48-52.
2004: Curry Benjamin J; Su Hua; Law Estelle G; McLaughlin Eileen A; Nixon Brett; Aitken R John
Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells.
Genomics 2004;84(2):406-18.
2004: Blackmore Daniel G; Baillie Lucan R; Holt Janet E; Dierkx Lynda; Aitken R John; McLaughlin Eileen A
Biosynthesis of the canine zona pellucida requires the integrated participation of both oocytes and granulosa cells.
Biology of reproduction 2004;71(2):661-8.
2004: Asquith Kelly L; Baleato Rosa M; McLaughlin Eileen A; Nixon Brett; Aitken R John
Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition.
Journal of cell science 2004;117(Pt 16):3645-57.
2004: Aitken R John; Baker Mark A; O'Bryan Moira
Shedding light on chemiluminescence: the application of chemiluminescence in diagnostic andrology.
Journal of andrology 2004;25(4):455-65.
2004: Baker Mark A; Krutskikh Anton; Curry Benjamin J; McLaughlin Eileen A; Aitken R John
Identification of cytochrome P450-reductase as the enzyme responsible for NADPH-dependent lucigenin and tetrazolium salt reduction in rat epididymal sperm preparations.
Biology of reproduction 2004;71(1):307-18.
2004: Aitken R John; Ryan Angela L; Baker Mark A; McLaughlin Eileen A
Redox activity associated with the maturation and capacitation of mammalian spermatozoa.
Free radical biology & medicine 2004;36(8):994-1010.
2004: Ecroyd Heath; Asquith Kelly L; Jones Russell C; Aitken R John
The development of signal transduction pathways during epididymal maturation is calcium dependent.
Developmental biology 2004;268(1):53-63.
2004: Baker Mark A; Aitken R John
The importance of redox regulated pathways in sperm cell biology.
Molecular and cellular endocrinology 2004;216(1-2):47-54.
2004: Curry Benjamin J; Roman Shaun D; Wallace Ceanne A; Scott Rebecca; Miriami Elana; Aitken R John
Identification and characterization of a novel splice variant of mouse and rat cytochrome b5/cytochrome b5 reductase.
Genomics 2004;83(3):425-38.
2004: Bennetts Liga; Lin Minjie; Aitken R John
Cyclic AMP-dependent tyrosine phosphorylation in tammar wallaby (Macropus eugenii) spermatozoa.
Journal of experimental zoology. Part A, Comparative experimental biology 2004;301(2):118-30.
2004: Sidhu K S; Mate K E; Gunasekera T; Veal D; Hetherington L; Baker M A; Aitken R J; Rodger J C
A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula).
Reproduction (Cambridge, England) 2004;127(1):95-103.
2004: Baker Mark A; Hetherington Louise; Ecroyd Heath; Roman Shaun D; Aitken R John
Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation.
Journal of cell science 2004;117(Pt 2):211-22.
2004: Aitken R John
Founders' Lecture. Human spermatozoa: fruits of creation, seeds of doubt.
Reproduction, fertility, and development 2004;16(7):655-64.
2004: Aitken R John; Baker Mark A
Oxidative stress and male reproductive biology.
Reproduction, fertility, and development 2004;16(5):581-8.
2003: Wade M A; Roman S D; Jones R C; Aitken R J
Adenylyl cyclase isoforms in rat testis and spermatozoa from the cauda epididymidis.
Cell and tissue research 2003;314(3):411-9.
2003: Ecroyd Heath; Jones Russell C; Aitken R John
Tyrosine phosphorylation of HSP-90 during mammalian sperm capacitation.
Biology of reproduction 2003;69(6):1801-7.
2003: Aitken R J; Ryan A L; Curry B J; Baker M A
Multiple forms of redox activity in populations of human spermatozoa.
Molecular human reproduction 2003;9(11):645-61.
2003: Sawyer Dennis E; Mercer Belinda G; Wiklendt Agnieszka M; Aitken R John
Quantitative analysis of gene-specific DNA damage in human spermatozoa.
Mutation research 2003;529(1-2):21-34.
2003: McLaughlin Eileen A; Holland Michael K; Aitken R John
Contraceptive vaccines.
Expert opinion on biological therapy 2003;3(5):829-41.
2003: Aitken R John; Baker Mark A; Sawyer Dennis
Oxidative stress in the male germ line and its role in the aetiology of male infertility and genetic disease.
Reproductive biomedicine online 2003;7(1):65-70.
2003: Ecroyd Heath W; Jones Russell C; Aitken R John
Endogenous redox activity in mouse spermatozoa and its role in regulating the tyrosine phosphorylation events associated with sperm capacitation.
Biology of reproduction 2003;69(1):347-54.
2003: Baker Mark A; Krutskikh Anton; Aitken R John
Biochemical entities involved in reactive oxygen species generation by human spermatozoa.
Protoplasma 2003;221(1-2):145-51.
2003: Baker Mark A; Lewis Beverley; Hetherington Louise; Aitken R John
Development of the signalling pathways associated with sperm capacitation during epididymal maturation.
Molecular reproduction and development 2003;64(4):446-57.
2003: Wade M A; Jones R C; Murdoch R N; Aitken R J
Motility activation and second messenger signalling in spermatozoa from rat cauda epididymidis.
Reproduction (Cambridge, England) 2003;125(2):175-83.
2003: Aitken R John; Sawyer Dennis
The human spermatozoon--not waving but drowning.
Advances in experimental medicine and biology 2003;518():85-98.
2002: Aitken R John
Immunocontraceptive vaccines for human use.
Journal of reproductive immunology 2002;57(1-2):273-87.
2002: Lin M; Hess R; Aitken R J
Induction of sperm maturation in vitro in epididymal cell cultures of the tammar wallaby (Macropus eugenii): disruption of motility initiation and sperm morphogenesis by inhibition of actin polymerization.
Reproduction (Cambridge, England) 2002;124(1):107-17.
2002: Aitken R John; Marshall Graves Jennifer A
The future of sex.
Nature 2002;415(6875):963.
2001: Aitken R J; Krausz C
Oxidative stress, DNA damage and the Y chromosome.
Reproduction (Cambridge, England) 2001;122(4):497-506.
2001: Scarlett C J; Lin M; Aitken R J
Actin polymerisation during morphogenesis of the acrosome as spermatozoa undergo epididymal maturation in the tammar wallaby (Macropus eugenii).
Journal of anatomy 2001;198(Pt 1):93-101.
2001: Sawyer D E; Roman S D; Aitken R J
Relative susceptibilities of mitochondrial and nuclear DNA to damage induced by hydrogen peroxide in two mouse germ cell lines.
Redox report : communications in free radical research 2001;6(3):182-4.
2000: Aitken R J
Possible redox regulation of sperm motility activation.
Journal of andrology 2000;21(4):491-6.
2000: Lin M; Zhang X; Murdoch R; Aitken R J
In vitro culture of brushtail possum (Trichosurus vulpecula) epididymal epithelium and induction of epididymal sperm maturation in co-culture.
Journal of reproduction and fertility 2000;119(1):1-14.

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