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Jan Voorberg

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Anatomy

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Hemophilia A

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Nicoletta Sorvillo; Anja Ten Brinke; Simon D van Haren; Rob Fijnheer; P H P Kaijen; Alexander B Meijer; Jan Voorberg
Preferential HLA-DRB1*11-dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells.
Jiong-Wei Wang; Eveline A M Bouwens; Hetty C de Boer; Koen Mertens; Maria Carolina Pintao; Pieter H Reitsma; Huma Safdar; Karin Valentijn; Jan Voorberg; J C J Eikenboom
Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.
A Wroblewska; Kathleen P Pratt; Birgit M Reipert; Jan Voorberg
Dangerous liaisons: how the immune system deals with factor VIII.

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2013: Nicoletta Sorvillo; Anja Ten Brinke; Simon D van Haren; Rob Fijnheer; P H P Kaijen; Alexander B Meijer; Jan Voorberg
Preferential HLA-DRB1*11-dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells.
Blood 2013;121(17):3502-10.
2013: Jiong-Wei Wang; Eveline A M Bouwens; Hetty C de Boer; Koen Mertens; Maria Carolina Pintao; Pieter H Reitsma; Huma Safdar; Karin Valentijn; Jan Voorberg; J C J Eikenboom
Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.
Blood 2013;121(14):2762-72.
2013: A Wroblewska; Kathleen P Pratt; Birgit M Reipert; Jan Voorberg
Dangerous liaisons: how the immune system deals with factor VIII.
Journal of thrombosis and haemostasis : JTH 2013;11(1):47-55.
2012: Bieuwke S Dragt; Ellen L van Agtmaal; Bas de Laat; Jan Voorberg
Effect of laminar shear stress on the distribution of Weibel-Palade bodies in endothelial cells.
Thrombosis research 2012;130(5):741-5.
2012: J W Wang; B S Dragt; Pieter H Reitsma; Jack A Valentijn; Karin Valentijn; Jan Voorberg; J C J Eikenboom
Formation of platelet-binding von Willebrand factor strings on non-endothelial cells.
Journal of thrombosis and haemostasis : JTH 2012;10(10):2168-78.
2012: Javier Martin-Ramirez; Maartje van den Biggelaar; Robert P Hebbel; Menno Hofman; Jan Voorberg
Establishment of outgrowth endothelial cells from peripheral blood.
Nature protocols 2012;7(9):1709-15.
2012: Kathinka W E M van Hooren; Jan A van Mourik; Jan Voorberg; Mar Fernandez-Borja; Ellen L van Agtmaal; ruben bierings
The Epac-Rap1 signaling pathway controls cAMP-mediated exocytosis of Weibel-Palade bodies in endothelial cells.
The Journal of biological chemistry 2012;287(29):24713-20.
2012: Jiong-Wei Wang; Guy Cosemans; Richard J Dirven; Dafna J Groeneveld; Pieter H Reitsma; Karine M Valentijn; Jan Voorberg; J C J Eikenboom
Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation.
Haematologica 2012;97(6):859-66.
2012: Aleksandra Wroblewska; X Long Zheng; Eszter Herczenik; Sheng-Yu Jin; P H P Kaijen; Alexander B Meijer; Aleksandra Ruminska; Anja ten Brinke; Maartje van den Biggelaar; Simon D van Haren; Jan Voorberg
Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice.
Blood 2012;119(22):5294-300.
2012: Dorothee van Breevoort; ruben bierings; Ilze Dienava-Verdoold; Bieuwke S Dragt; Jeroen C Eikenboom; Mar Fernandez-Borja; Jacqueline Klein Gebbinck; Anton J G Horrevoets; Astrid Kragt; Alexander B Meijer; Karine M Valentijn; Ellen L van Agtmaal; Jan Voorberg
Proteomic screen identifies IGFBP7 as a novel component of endothelial cell-specific Weibel-Palade bodies.
Journal of proteome research 2012;11(5):2925-36.
2012: Johanna A Kremer Hovinga; Jan Voorberg
Improving on nature: redesigning ADAMTS13.
Blood 2012;119(16):3654-5.
2012: Nicoletta Sorvillo; Linda M van den Berg; Rob Fijnheer; Teunis B Geijtenbeek; Eszter Herczenik; Luisa Martinez-Pomares; Wouter Pos; Jan Voorberg
The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells.
Blood 2012;119(16):3828-35.
2012: Christopher L Chavez; Jacqueline N Chu; Vanessa E Cuéllar; Alfonso P Farruggio; Annahita Keravala; Jan Voorberg; Michele P Calos
Long-term expression of human coagulation factor VIII in a tolerant mouse model using the φC31 integrase system.
Human gene therapy 2012;23(4):390-8.
2012: Rahel Froehlich-Zahnd; James N George; Khatira Aboulfatova; Ulrich Budde; Jing-Fei Dong; Bernhard Lämmle; Brenda M Luken; Irmela Sulzer; Deirdra R Terrell; Sara K Vesely; Jan Voorberg; Johanna A Kremer-Hovinga
Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura.
Haematologica 2012;97(2):297-303.
2012: Eszter Herczenik; P H P Kaijen; Luisa Martinez-Pomares; Alexander B Meijer; Anja ten Brinke; Maartje van den Biggelaar; Simon D van Haren; Aleksandra Wroblewska; Jan Voorberg
Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain.
The Journal of allergy and clinical immunology 2012;129(2):501-9, 509.e1-5.
2012: Ellen L van Agtmaal; ruben bierings; Bieuwke S Dragt; Mar Fernandez-Borja; Anton J G Horrevoets; Thomas A Leyen; Jan Voorberg
The shear stress-induced transcription factor KLF2 affects dynamics and angiopoietin-2 content of Weibel-Palade bodies.
PloS one 2012;7(6):e38399.
2011: Eveline A M Bouwens; Jeroen C J Eikenboom; Marjon J Mourik; Karine M Valentijn; Maartje van den Biggelaar; Jan Voorberg; Koen Mertens
Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies.
Blood 2011;118(22):5947-56.
2011: Wouter Pos; Nicoletta Sorvillo; Gestur Vidarsson; Hendrik B Feys; Rob Fijnheer; P H P Kaijen; Jan Voorberg
Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain.
Haematologica 2011;96(11):1670-7.
2011: Juan Xiao; Jing Xue; Sheng-Yu Jin; Nicoletta Sorvillo; Jan Voorberg; X Long Zheng
Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(10):2261-9.
2011: Jiong-Wei Wang; Hetty C de Boer; Richard J Dirven; Abraham Koster; Pieter H Reitsma; Karine M Valentijn; Anton-Jan van Zonneveld; Jan Voorberg; J C J Eikenboom
Intracellular storage and regulated secretion of von Willebrand factor in quantitative von Willebrand disease.
The Journal of biological chemistry 2011;286(27):24180-8.
2011: Wouter Pos; N Sorvillo; Brenda M Luken; J A Kremer Hovinga; Jan Voorberg
Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura.
Journal of thrombosis and haemostasis : JTH 2011;9(7):1285-91.
2011: Simon D van Haren; Eszter Herczenik; Anja ten Brinke; Koen Mertens; Jan Voorberg; Alexander B Meijer
HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII.
Molecular & cellular proteomics : MCP 2011;10(6):M110.002246.
2011: Karine M Valentijn; J Evan Sadler; Jack A Valentijn; Jan Voorberg; J C J Eikenboom
Functional architecture of Weibel-Palade bodies.
Blood 2011;117(19):5033-43.
2011: I Dienava-Verdoold; M G Boon-Spijker; Philip G de Groot; Herm-Jan Brinkman; Jan Voorberg; Koen Mertens; R H W M Derksen; Bas de Laat
Patient-derived monoclonal antibodies directed towards beta2 glycoprotein-1 display lupus anticoagulant activity.
Journal of thrombosis and haemostasis : JTH 2011;9(4):738-47.
2011: Eddie A James; S D van Haren; R A Ettinger; K Fijnvandraat; J A Liberman; William W Kwok; Jan Voorberg; Kathleen P Pratt
T-cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site.
Journal of thrombosis and haemostasis : JTH 2011;9(4):689-99.
2011: Simon D van Haren; Jan Voorberg
Getting rid of bad memory.
Blood 2011;117(1):7-8.
2011: Maartje van den Biggelaar; Jan Voorberg; Eveline A M Bouwens; Koen Mertens
Storage of factor VIII variants with impaired von Willebrand factor binding in Weibel-Palade bodies in endothelial cells.
PloS one 2011;6(8):e24163.
2010: P M W van Helden; P H P Kaijen; Eveline P Mauser-Bunschoten; Kathelijn Fischer; H Marijke van den Berg; Jan Voorberg
Domain specificity of factor VIII inhibitors during immune tolerance induction in patients with haemophilia A.
Haemophilia : the official journal of the World Federation of Hemophilia 2010;16(6):892-901.
2010: P M W van Helden; S D Van Haren; K Fijnvandraat; H Marijke van den Berg; Jan Voorberg
Factor VIII-specific B cell responses in haemophilia A patients with inhibitors.
Haemophilia : the official journal of the World Federation of Hemophilia 2010;16(102):35-43.
2010: Wouter Pos; James T B Crawley; Rob Fijnheer; Jan Voorberg; David A Lane; Brenda M Luken
An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF.
Blood 2010;115(8):1640-9.
2009: Maartje van den Biggelaar; Eveline A M Bouwens; Neeltje Kootstra; Robert P Hebbel; Jan Voorberg; Koen Mertens
Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells.
Haematologica 2009;94(5):670-8.
2009: Maartje van den Biggelaar; Alexander B Meijer; Jan Voorberg; Koen Mertens
Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles.
Blood 2009;113(13):3102-9.
2008: Pauline M W van Helden; H Marijke van den Berg; Samantha C Gouw; Paul H P Kaijen; Marleen G Zuurveld; Evelien P Mauser-Bunschoten; Rob C Aalberse; Gestur Vidarsson; Jan Voorberg
IgG subclasses of anti-FVIII antibodies during immune tolerance induction in patients with hemophilia A.
British journal of haematology 2008;142(4):644-52.
2008: Mariska G Rondaij; ruben bierings; Ellen L van Agtmaal; Karina A Gijzen; Erica Sellink; Astrid Kragt; Stephen S G Ferguson; Koen Mertens; Matthew J Hannah; Jan A van Mourik; Mar Fernandez-Borja; Jan Voorberg
Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells.
Blood 2008;112(1):56-63.
2008: Jan Voorberg
Slipping out the Weibel-Palade body.
Blood 2008;111(11):5264-5.
2007: ruben bierings; M van den Biggelaar; Astrid Kragt; Koen Mertens; Jan Voorberg; Jan A van Mourik
Efficiency of von Willebrand factor-mediated targeting of interleukin-8 into Weibel-Palade bodies.
Journal of thrombosis and haemostasis : JTH 2007;5(12):2512-9.
2007: P M W van Helden; P H P Kaijen; Karin Fijnvandraat; H Marijke van den Berg; Jan Voorberg
Factor VIII-specific memory B cells in patients with hemophilia A.
Journal of thrombosis and haemostasis : JTH 2007;5(11):2306-8.
2007: M van den Biggelaar; ruben bierings; G Storm; Jan Voorberg; Koen Mertens
Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies.
Journal of thrombosis and haemostasis : JTH 2007;5(11):2235-42.
2007: Niels P Riksen; Brenda M Luken; Ina S Klasen; Jan Voorberg; Niels Crama; Marcel van Deuren
Antibodies against the CUB1-2 domains of ADAMTS13 in a patient with benign monoclonal gammopathy: no causal relationship.
Haematologica 2007;92(7):e74-6.
2006: Pernilla Tjernberg; Hans L Vos; Caroline C Spaargaren-van Riel; Brenda M Luken; Jan Voorberg; Rogier M Bertina; J C J Eikenboom
Differential effects of the loss of intrachain- versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand disease.
Thrombosis and haemostasis 2006;96(6):717-24.
2006: Brenda M Luken; P H P Kaijen; Ellen A M Turenhout; Johanna A Kremer-Hovinga; Jan A van Mourik; Rob Fijnheer; Jan Voorberg
Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura.
Journal of thrombosis and haemostasis : JTH 2006;4(11):2355-64.
2006: Brenda M Luken; Ellen A M Turenhout; P H P Kaijen; Mascha J Greuter; Wouter Pos; Jan A van Mourik; Rob Fijnheer; Jan Voorberg
Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP.
Thrombosis and haemostasis 2006;96(3):295-301.
2006: Niels Bovenschen; Gunny Van Stempvoort; Jan Voorberg; Koen Mertens; Alexander B Meijer
Proteolytic cleavage of factor VIII heavy chain is required to expose the binding-site for low-density lipoprotein receptor-related protein within the A2 domain.
Journal of thrombosis and haemostasis : JTH 2006;4(7):1487-93.
2006: Rob J Dekker; Reinier A Boon; Mariska G Rondaij; Astrid Kragt; Oscar L Volger; Yvonne W Elderkamp; Joost C M Meijers; Jan Voorberg; Hans Pannekoek; Anton J G Horrevoets
KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium.
Blood 2006;107(11):4354-63.
2006: Mariska G Rondaij; ruben bierings; Astrid Kragt; Jan A van Mourik; Jan Voorberg
Dynamics and plasticity of Weibel-Palade bodies in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(5):1002-7.
2006: Wendy S Bril; Pauline M W van Helden; Christina Hausl; Marleen G Zuurveld; Rafi U Ahmad; Martine J Hollestelle; Pieter H Reitsma; Karin Fijnvandraat; René A W van Lier; Hans Peter Schwarz; Koen Mertens; Birgit M Reipert; Jan Voorberg
Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution.
Thrombosis and haemostasis 2006;95(2):341-7.
2006: Mariska G Rondaij; ruben bierings; Astrid Kragt; Karina A Gijzen; Erica Sellink; Jan A van Mourik; Mar Fernandez-Borja; Jan Voorberg
Dynein-dynactin complex mediates protein kinase A-dependent clustering of Weibel-Palade bodies in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):49-55.
2005: Deborah A Lewis; Niels Bovenschen; Koen Mertens; Jan Voorberg; Thomas L Ortel
Phospholipid vesicles interfere with the binding of antibody fragments to the light chain of factor VIII.
Thrombosis and haemostasis 2005;93(5):833-41.
2005: Brenda M Luken; Ellen A M Turenhout; Janine J J Hulstein; Jan A van Mourik; Rob Fijnheer; Jan Voorberg
The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura.
Thrombosis and haemostasis 2005;93(2):267-74.
2004: Wendy S Bril; P E MacLean; P H P Kaijen; Edward N van den Brink; N M Lardy; Karin Fijnvandraat; Marjolein Peters; Jan Voorberg
HLA class II genotype and factor VIII inhibitors in mild haemophilia A patients with an Arg593 to Cys mutation.
Haemophilia : the official journal of the World Federation of Hemophilia 2004;10(5):509-14.
2004: Mariska G Rondaij; Erica Sellink; Karina A Gijzen; Jean Paul ten Klooster; Peter L Hordijk; Jan A van Mourik; Jan Voorberg
Small GTP-binding protein Ral is involved in cAMP-mediated release of von Willebrand factor from endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(7):1315-20.
2003: Simone M Schatz; Peter L Turecek; Christian Fiedler; Klaus Zimmermann; Herbert Gritsch; Jan Voorberg; Hans Peter Schwarz; Friedrich Dorner; Friedrich Scheiflinger
Evaluation of the haemostatic potential of factor VIII-heparin cofactor II hybrid proteins in a mouse model.
British journal of haematology 2003;123(4):692-5.
2003: Thalia Romani de Wit; Hubert P J C de Leeuw; Mariska G Rondaij; Rozalia T M de Laaf; Erica Sellink; Herm-Jan Brinkman; Jan Voorberg; Jan A van Mourik
Von Willebrand factor targets IL-8 to Weibel-Palade bodies in an endothelial cell line.
Experimental cell research 2003;286(1):67-74.
2003: Thalia Romani de Wit; Mariska G Rondaij; Peter L Hordijk; Jan Voorberg; Jan A van Mourik
Real-time imaging of the dynamics and secretory behavior of Weibel-Palade bodies.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(5):755-61.
2003: Niels Bovenschen; Ria C Boertjes; Gunny Van Stempvoort; Jan Voorberg; Peter J Lenting; Alexander B Meijer; Koen Mertens
Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.
The Journal of biological chemistry 2003;278(11):9370-7.
2003: Karin Fijnvandraat; Wendy S Bril; Jan Voorberg
Immunobiology of inhibitor development in hemophilia A.
Seminars in thrombosis and hemostasis 2003;29(1):61-8.
2002: Wendy S Bril; Ellen A M Turenhout; P H P Kaijen; Edward N van den Brink; Maria M W Koopman; Marjolein Peters; Jan Voorberg
Analysis of factor VIII inhibitors in a haemophilia A patient with an Arg593-->Cys mutation using phage display.
British journal of haematology 2002;119(2):393-6.
2002: Edward N van den Brink; Wendy S Bril; Ellen A M Turenhout; Marleen Zuurveld; Niels Bovenschen; Marjolein Peters; Thynn Thynn Yee; Koen Mertens; Deborah A Lewis; Thomas L Ortel; Pete Lollar; Dorothea Scandella; Jan Voorberg
Two classes of germline genes both derived from the V(H)1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII.
Blood 2002;99(8):2828-34.
2002: André J Vlot; Shulamiet Wittebol; P F W Strengers; Ellen A M Turenhout; Jan Voorberg; H Marijke van den Berg; Eveline P Mauser-Bunschoten
Factor VIII inhibitor in a patient with mild haemophilia A and an Asn618-->Ser mutation responsive to immune tolerance induction and cyclophosphamide.
British journal of haematology 2002;117(1):136-40.
2002: Jan A van Mourik; Thalia Romani de Wit; Jan Voorberg
Biogenesis and exocytosis of Weibel-Palade bodies.
Histochemistry and cell biology 2002;117(2):113-22.
2001: Hubert P J C de Leeuw; Mar Fernandez-Borja; Eric Reits; Thalia Romani de Wit; P M Wijers-Koster; Peter L Hordijk; Jacques Neefjes; Jan A van Mourik; Jan Voorberg
Small GTP-binding protein Ral modulates regulated exocytosis of von Willebrand factor by endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(6):899-904.
2001: Edward N van den Brink; Ellen A M Turenhout; Niels Bovenschen; B G Heijnen; Koen Mertens; Marjolein Peters; Jan Voorberg
Multiple VH genes are used to assemble human antibodies directed toward the A3-C1 domains of factor VIII.
Blood 2001;97(4):966-72.
2000: Edward N van den Brink; Ellen A M Turenhout; E C Wijn-Maas; F J van der Meer; Jan Voorberg; L J Bosch
Disappearance of factor VIII autoantibodies preceding autoimmune haemolytic anaemia.
Haemophilia : the official journal of the World Federation of Hemophilia 2000;6(6):698-701.
2000: Edward N van den Brink; Ellen A M Turenhout; C M Bank; Karin Fijnvandraat; Marjolein Peters; Jan Voorberg
Molecular analysis of human anti-factor VIII antibodies by V gene phage display identifies a new epitope in the acidic region following the A2 domain.
Blood 2000;96(2):540-5.
2000: J C Roelse; R T De Laaf; Sarah Timmermans; Marjolein Peters; Jan A van Mourik; Jan Voorberg
Intracellular accumulation of factor VIII induced by missense mutations Arg593-->Cys and Asn618-->Ser explains cross-reacting material-reduced haemophilia A.
British journal of haematology 2000;108(2):241-6.
2000: Edward N van den Brink; Ellen A M Turenhout; J Davies; Niels Bovenschen; Karin Fijnvandraat; W H Ouwehand; Marjolein Peters; Jan Voorberg
Human antibodies with specificity for the C2 domain of factor VIII are derived from VH1 germline genes.
Blood 2000;95(2):558-63.
2000: Jan Voorberg; Edward N van den Brink
Phage display technology: a tool to explore the diversity of inhibitors to blood coagulation factor VIII.
Seminars in thrombosis and hemostasis 2000;26(2):143-50.
1999: Hubert P J C de Leeuw; P M Wijers-Koster; Jan A van Mourik; Jan Voorberg
Small GTP-binding protein RalA associates with Weibel-Palade bodies in endothelial cells.
Thrombosis and haemostasis 1999;82(3):1177-81.
1999: H Marijke van den Berg; Goris Roosendaal; Jan Voorberg; Eveline P Mauser-Bunschoten
Inhibitor development in a multitransfused patient with severe haemophilia A.
Thrombosis and haemostasis 1999;82(1):151-2.
1999: Edward N van den Brink; Sarah Timmermans; Ellen A M Turenhout; C M Bank; Karin Fijnvandraat; Jan Voorberg; Marjolein Peters
Longitudinal analysis of factor VIII inhibitors in a previously untreated mild haemophilia A patient with an Arg593-->Cys substitution.
Thrombosis and haemostasis 1999;81(5):723-6.
1998: Hubert P J C de Leeuw; P M Koster; J Calafat; H Janssen; Anton-Jan van Zonneveld; Jan A van Mourik; Jan Voorberg
Small GTP-binding proteins in human endothelial cells.
British journal of haematology 1998;103(1):15-9.
1998: Karin Fijnvandraat; Patrick H N Celie; Ellen A M Turenhout; JW ten Cate; Jan A van Mourik; Koen Mertens; Marjolein Peters; Jan Voorberg
A human alloantibody interferes with binding of factor IXa to the factor VIII light chain.
Blood 1998;91(7):2347-52.
1997: Karin Fijnvandraat; Ellen A M Turenhout; Edward N van den Brink; JW ten Cate; Jan A van Mourik; Marjolein Peters; Jan Voorberg
The missense mutation Arg593 --> Cys is related to antibody formation in a patient with mild hemophilia A.
Blood 1997;89(12):4371-7.
1996: Alessandra Borchiellini; Karin Fijnvandraat; JW ten Cate; D Pajkrt; Sander J H van Deventer; G Pasterkamp; F Meijer-Huizinga; L Zwart-Huinink; Jan Voorberg; Jan A van Mourik
Quantitative analysis of von Willebrand factor propeptide release in vivo: effect of experimental endotoxemia and administration of 1-deamino-8-D-arginine vasopressin in humans.
Blood 1996;88(8):2951-8.
1996: Jan Voorberg; R T de Laaf; P M Koster; Jan A van Mourik
Intracellular retention of a factor VIII protein with an Arg2307-->Gln mutation as a cause of haemophilia A.
The Biochemical journal 1996;318 ( Pt 3)():931-7.
1996: Jan Voorberg; G van Stempvoort; J M Bos; Koen Mertens; Jan A van Mourik; M J Donath
Enhanced thrombin sensitivity of a factor VIII-heparin cofactor II hybrid.
The Journal of biological chemistry 1996;271(35):20985-8.
1996: Barbara Montaruli; Alessandra Borchiellini; Giacomo Tamponi; L Giorda; P Bessone; Jan A van Mourik; Jan Voorberg; Piercarla Schinco
Factor V Arg506-->Gln mutation in patients with antiphospholipid antibodies.
Lupus 1996;5(4):303-6.
1996: Barbara Montaruli; Jan Voorberg; Giacomo Tamponi; Alessandra Borchiellini; G Muleo; A Pannocchia; Jan A van Mourik; Piercarla Schinco
Arterial and venous thrombosis in two Italian families with the factor V Arg506-->Gln mutation.
European journal of haematology 1996;57(1):96-100.
1995: M J Donath; R T de Laaf; P T Biessels; Peter J Lenting; J W van de Loo; Jan A van Mourik; Jan Voorberg; Koen Mertens
Characterization of des-(741-1668)-factor VIII, a single-chain factor VIII variant with a fusion site susceptible to proteolysis by thrombin and factor Xa.
The Biochemical journal 1995;312 ( Pt 1)():49-55.
1995: J Spaargaren; peter giesen; M P Janssen; Jan Voorberg; George M Willems; Jan A van Mourik
Binding of blood coagulation factor VIII and its light chain to phosphatidylserine/phosphatidylcholine bilayers as measured by ellipsometry.
The Biochemical journal 1995;310 ( Pt 2)():539-45.
1994: Jan Voorberg; J Roelse; R Koopman; H Büller; F Berends; JW ten Cate; Koen Mertens; Jan A van Mourik
Association of idiopathic venous thromboembolism with single point-mutation at Arg506 of factor V.
Lancet 1994;343(8912):1535-6.
1993: Jan Voorberg; R Fontijn; Jero Calafat; Hans Janssen; Jan A van Mourik; Hans Pannekoek
Biogenesis of von Willebrand factor-containing organelles in heterologous transfected CV-1 cells.
The EMBO journal 1993;12(2):749-58.
1992: Anne-Sophie Ribba; Jan Voorberg; D Meyer; Hans Pannekoek; G Pietu
Characterization of recombinant von Willebrand factor corresponding to mutations in type IIA and type IIB von Willebrand disease.
The Journal of biological chemistry 1992;267(32):23209-15.
1991: Jan Voorberg; R Fontijn; Jero Calafat; Hans Janssen; Jan A van Mourik; Hans Pannekoek
Assembly and routing of von Willebrand factor variants: the requirements for disulfide-linked dimerization reside within the carboxy-terminal 151 amino acids.
The Journal of cell biology 1991;113(1):195-205.
1991: A Leyte; Jan Voorberg; H B Van Schijndel; B Duim; Hans Pannekoek; Jan A van Mourik
The pro-polypeptide of von Willebrand factor is required for the formation of a functional factor VIII-binding site on mature von Willebrand factor.
The Biochemical journal 1991;274 ( Pt 1)():257-61.
1990: Wim J M Van De Ven; Jan Voorberg; R Fontijn; H Pannekoek; Ans M W van den Ouweland; H L van Duijnhoven; Anton J M Roebroek; Roland Siezen
Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes.
Molecular biology reports 1990;14(4):265-75.
1990: Jan Voorberg; R Fontijn; Jan A van Mourik; Hans Pannekoek
Domains involved in multimer assembly of von willebrand factor (vWF): multimerization is independent of dimerization.
The EMBO journal 1990;9(3):797-803.
1989: H Pannekoek; Jan Voorberg
Molecular cloning, expression and assembly of multimeric von Willebrand factor.
Baillière's clinical haematology 1989;2(4):879-96.