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Kalpit Vora

Research Profile

Anatomy

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Physiology

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Genes, Immunoglobulin

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Peter M Gray; Zhiqiang Guo; Joseph Leone; Gene Porter; Julie A DeMartino; Gail Forrest; Daniel C Freed; Tong-Ming Fu; Thomas Wisniewski; Dennis M Zaller; Kalpit A Vora
Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities.
Kalpit A Vora; Gene Porter; Roche Peng; Yan Cui; Kellyann Pryor; George Eiermann; Dennis Zaller
Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses.
Swaminathan R Natarajan; Luping Liu; Mark Levorse; James E Thompson; Edward A O'Neill; Stephen J O'Keefe; Kalpit A Vora; Raymond J Cvetovich; John Y L Chung; Ester Carballo-Jane; Denise visco
p38 MAP kinase inhibitors. Part 5: discovery of an orally bio-available and highly efficacious compound based on the 7-amino-naphthyridone scaffold.

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All Publications

2012: Peter M Gray; Zhiqiang Guo; Joseph Leone; Gene Porter; Julie A DeMartino; Gail Forrest; Daniel C Freed; Tong-Ming Fu; Thomas Wisniewski; Dennis M Zaller; Kalpit A Vora
Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities.
Cellular immunology 2012;278(1-2):113-9.
2009: Kalpit A Vora; Gene Porter; Roche Peng; Yan Cui; Kellyann Pryor; George Eiermann; Dennis Zaller
Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses.
BMC immunology 2009;10():19.
2006: Swaminathan R Natarajan; Luping Liu; Mark Levorse; James E Thompson; Edward A O'Neill; Stephen J O'Keefe; Kalpit A Vora; Raymond J Cvetovich; John Y L Chung; Ester Carballo-Jane; Denise visco
p38 MAP kinase inhibitors. Part 5: discovery of an orally bio-available and highly efficacious compound based on the 7-amino-naphthyridone scaffold.
Bioorganic & medicinal chemistry letters 2006;16(20):5468-71.
2005: Francesco V Rao; Ole A Andersen; Kalpit A Vora; Julie A Demartino; Daan M F van Aalten
Methylxanthine drugs are chitinase inhibitors: investigation of inhibition and binding modes.
Chemistry & biology 2005;12(9):973-80.
2005: Kalpit A Vora; Elizabeth Nichols; Gene Porter; Yan Cui; Carol Ann Keohane; Richard Hajdu; Jeffrey Hale; William Neway; Dennis Zaller; Suzanne Mandala
Sphingosine 1-phosphate receptor agonist FTY720-phosphate causes marginal zone B cell displacement.
Journal of leukocyte biology 2005;78(2):471-80.
2003: Kalpit A Vora; Li Chun Wang; Sambasiva P Rao; Zhong-Ying Liu; Gerard R Majeau; Anne H Cutler; Paula S Hochman; Martin L Scott; Susan L Kalled
Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):547-51.
2002: Sambasiva P Rao; Kalpit A Vora; Tim Manser
Differential expression of the inhibitory IgG Fc receptor FcgammaRIIB on germinal center cells: implications for selection of high-affinity B cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):1859-68.
2001: Jeffrey S Thompson; Sarah A Bixler; Fang Qian; Kalpit A Vora; Martin L Scott; Teresa G Cachero; Cathy Hession; Pascal Schneider; Irene Sizing; Colleen Mullen; Kathy Strauch; Mohammad Zafari; Christopher D Benjamin; Jürg Tschopp; Jeffrey L Browning; Christine Ambrose
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF.
Science (New York, N.Y.) 2001;293(5537):2108-11.
2001: B Schiemann; J L Gommerman; Kalpit A Vora; Teresa G Cachero; Svetlana Shulga-Morskaya; Max Dobles; Erica Frew; Martin L Scott
An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.
Science (New York, N.Y.) 2001;293(5537):2111-4.
2001: Kalpit A Vora; VM Lentz; W Monsell; Sambasiva P Rao; Richard V Mettus; A Toscani; E Premkumar Reddy; Tim Manser
The T cell-dependent B cell immune response and germinal center reaction are intact in A-myb-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3226-30.
2000: D Qin; Jiuhua Wu; Kalpit A Vora; JV Ravetch; Andras K Szakal; Tim Manser; John G Tew
Fc gamma receptor IIB on follicular dendritic cells regulates the B cell recall response.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6268-75.
1999: Kalpit A Vora; KM Tumas-Brundage; Tim Manser
Contrasting the in situ behavior of a memory B cell clone during primary and secondary immune responses.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4315-27.
1999: Kalpit A Vora; KM Tumas-Brundage; VM Lentz; A Cranston; Richard Fishel; Tim Manser
Severe attenuation of the B cell immune response in Msh2-deficient mice.
The Journal of experimental medicine 1999;189(3):471-82.
1998: Tim Manser; KM Tumas-Brundage; L P Casson; A M Giusti; S Hande; Evangelia Notidis; Kalpit A Vora
The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment.
Immunological reviews 1998;162():183-96.
1998: Kalpit A Vora; KM Tumas-Brundage; Tim Manser
A periarteriolar lymphoid sheath-associated B cell focus response is not observed during the development of the anti-arsonate germinal center reaction.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):728-33.
1998: Kalpit A Vora; JV Ravetch; Tim Manser
Insights into the mechanisms of antibody-affinity maturation and the generation of the memory B-cell compartment using genetically altered mice.
Developmental immunology 1998;6(3-4):305-16.
1997: Kalpit A Vora; JV Ravetch; Tim Manser
Amplified follicular immune complex deposition in mice lacking the Fc receptor gamma-chain does not alter maturation of the B cell response.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(5):2116-24.
1997: KM Tumas-Brundage; Kalpit A Vora; Tim Manser
Evaluation of the role of the 3'alpha heavy chain enhancer [3'alpha E(hs1,2)] in Vh gene somatic hypermutation.
Molecular immunology 1997;34(5):367-78.
1996: KM Tumas-Brundage; Kalpit A Vora; A M Giusti; Tim Manser
Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches.
Seminars in immunology 1996;8(3):141-50.
1995: Kalpit A Vora; Tim Manser
Altering the antibody repertoire via transgene homologous recombination: evidence for global and clone-autonomous regulation of antigen-driven B cell differentiation.
The Journal of experimental medicine 1995;181(1):271-81.