FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Rob Voskuyl

Research Profile

Living Beings

Chemicals & Drugs

Procedures

Concepts & Ideas

Disorders

Anatomy

Co-author Network

Publications

TOP 3
Stina Syvänen; Yoshihiko Tagawa; Albert D Windhorst; Elizabeth C de Lange; Jonas Eriksson; Maaike Labots; Adriaan A Lammertsma; Rob A Voskuyl
Altered GABAA receptor density and unaltered blood-brain barrier transport in a kainate model of epilepsy: an in vivo study using 11C-flumazenil and PET.
Stina Syvänen; Dirk-Jan van den Berg; Rob A Voskuyl; Maarten Schenke; Elizabeth C de Lange
Alteration in P-glycoprotein functionality affects intrabrain distribution of quinidine more than brain entry-a study in rats subjected to status epilepticus by kainate.
Julia Müllauer; Markus Müller; Rob A Voskuyl; Jens P Bankstahl; Martin Bauer; Claudia Kuntner; Oliver Langer; Stina Syvänen
Pharmacokinetic modeling of P-glycoprotein function at the rat and human blood-brain barriers studied with (R)-[11C]verapamil positron emission tomography.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Rob Voskuyl (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Stina Syvänen; Yoshihiko Tagawa; Albert D Windhorst; Elizabeth C de Lange; Jonas Eriksson; Maaike Labots; Adriaan A Lammertsma; Rob A Voskuyl
Altered GABAA receptor density and unaltered blood-brain barrier transport in a kainate model of epilepsy: an in vivo study using 11C-flumazenil and PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(12):1974-83.
2012: Stina Syvänen; Dirk-Jan van den Berg; Rob A Voskuyl; Maarten Schenke; Elizabeth C de Lange
Alteration in P-glycoprotein functionality affects intrabrain distribution of quinidine more than brain entry-a study in rats subjected to status epilepticus by kainate.
The AAPS journal 2012;14(1):87-96.
2012: Julia Müllauer; Markus Müller; Rob A Voskuyl; Jens P Bankstahl; Martin Bauer; Claudia Kuntner; Oliver Langer; Stina Syvänen
Pharmacokinetic modeling of P-glycoprotein function at the rat and human blood-brain barriers studied with (R)-[11C]verapamil positron emission tomography.
EJNMMI research 2012;2(1):58.
2012: Joost Verbeek; Rob A Voskuyl; Elizabeth C M de Lange; Jonas Eriksson; Maaike Labots; Adriaan A Lammertsma; Martinus P J Mooijer; Marissa Rongen; Stina Syvänen; Albert D Windhorst
[11C]phenytoin revisited: synthesis by [11C]CO carbonylation and first evaluation as a P-gp tracer in rats.
EJNMMI research 2012;2(1):36.
2012: Femke E Froklage; Jan J Heimans; N Harry Hendrikse; Marc C Huisman; Adriaan A Lammertsma; Carla F M Molthoff; Jaap C Reijneveld; Stina Syvänen; Yoshihiko Tagawa; Elizabeth Cm de Lange; Jonas Eriksson; Rob A Voskuyl
[11C]Flumazenil brain uptake is influenced by the blood-brain barrier efflux transporter P-glycoprotein.
EJNMMI research 2012;2():12.
2011: Stina Syvänen; Yoshihiko Tagawa; Albert D Windhorst; Elizabeth C de Lange; Adriaan A Lammertsma; Carla F M Molthoff; Maarten Schenke; Rob A Voskuyl
Simultaneous in vivo measurements of receptor density and affinity using [11C]flumazenil and positron emission tomography: comparison of full saturation and steady state methods.
NeuroImage 2011;57(3):928-37.
2011: Stina Syvänen; Gert Luurtsema; Carla F M Molthoff; Albert D Windhorst; Marc C Huisman; Adriaan A Lammertsma; Rob A Voskuyl; Elizabeth C de Lange
(R)-[11C]verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus.
BMC medical imaging 2011;11():1.
2009: Lia C Liefaard; Bart A Ploeger; Carla F M Molthoff; Hugo W A M de Jong; Jouke Dijkstra; Louise van der Weerd; Adriaan A Lammertsma; Meindert Danhof; Rob A Voskuyl
Changes in GABAA receptor properties in amygdala kindled animals: in vivo studies using [11C]flumazenil and positron emission tomography.
Epilepsia 2009;50(1):88-98.
2008: Anouk E Muller; P Joep Dörr; Johan W Mouton; Joost De Jongh; Paul M Oostvogel; Eric A P Steegers; Rob A Voskuyl; Meindert Danhof
The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women.
British journal of clinical pharmacology 2008;66(6):866-74.
2008: Meindert Danhof; Elizabeth C M de Lange; Oscar Della-Pasqua; Bart A Ploeger; Rob A Voskuyl
Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research.
Trends in pharmacological sciences 2008;29(4):186-91.
2007: Lia C Liefaard; Rou-Afza F Gunput; Meindert Danhof; Rob A Voskuyl
Decreased Efficacy of GABAA-receptor modulation by midazolam in the kainate model of temporal lobe epilepsy.
Epilepsia 2007;48(7):1378-87.
2007: Erwin A Van Vliet; Rosalinde van Schaik; Peter M Edelbroek; Rob A Voskuyl; Sandra Redeker; Eleonora Aronica; Wytse J Wadman; Jan A Gorter
Region-specific overexpression of P-glycoprotein at the blood-brain barrier affects brain uptake of phenytoin in epileptic rats.
The Journal of pharmacology and experimental therapeutics 2007;322(1):141-7.
2007: Daniël M Jonker; Rob A Voskuyl; Meindert Danhof
Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments?
Epilepsia 2007;48(3):412-34.
2007: Meindert Danhof; Joost de Jongh; Elizabeth C M de Lange; Oscar Della-Pasqua; Bart A Ploeger; Rob A Voskuyl
Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis.
Annual review of pharmacology and toxicology 2007;47():357-400.
2005: Lia C Liefaard; Bart A Ploeger; Carla F M Molthoff; Ronald Boellaard; Adriaan A Lammertsma; Meindert Danhof; Rob A Voskuyl
Population pharmacokinetic analysis for simultaneous determination of B (max) and K (D) in vivo by positron emission tomography.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2005;7(6):411-21.
2005: Daniël M Jonker; Sandra A G Visser; Piet H van Der Graaf; Rob A Voskuyl; Meindert Danhof
Towards a mechanism-based analysis of pharmacodynamic drug-drug interactions in vivo.
Pharmacology & therapeutics 2005;106(1):1-18.
2004: Daniël M Jonker; Rob A Voskuyl; Meindert Danhof
Pharmacodynamic analysis of the anticonvulsant effects of tiagabine and lamotrigine in combination in the rat.
Epilepsia 2004;45(5):424-35.
2003: Daniël M Jonker; C van de Mheen; Paul H C Eilers; MR Kruk; Rob A Voskuyl; Meindert Danhof
Anticonvulsant drugs differentially suppress individual ictal signs: a pharmacokinetic/pharmacodynamic analysis in the cortical stimulation model in the rat.
Behavioral neuroscience 2003;117(5):1076-85.
2003: Daniël M Jonker; Dick A C Vermeij; Peter M Edelbroek; Rob A Voskuyl; Vladimir K Piotrovsky; Meindert Danhof
Pharmacodynamic analysis of the interaction between tiagabine and midazolam with an allosteric model that incorporates signal transduction.
Epilepsia 2003;44(3):329-38.
2000: Anne-Marie Cleton; B A Altorf; Rob A Voskuyl; Meindert Danhof
Pharmacokinetic-pharmacodynamic modelling of tiagabine CNS effects upon chronic treatment in rats: lack of change in concentration-EEG effect relationship.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;12(2):141-50.
2000: Anne-Marie Cleton; B A Altorf; Rob A Voskuyl; Meindert Danhof
Effect of amygdala kindling on the central nervous system effects of tiagabine: EEG effects versus brain GABA levels.
British journal of pharmacology 2000;130(5):1037-44.
2000: OE Della Paschoa; A Hoogerkamp; Peter M Edelbroek; Rob A Voskuyl; Meindert Danhof
Pharmacokinetic-pharmacodynamic correlation of lamotrigine, flunarizine, loreclezole, CGP40116 and CGP39551 in the cortical stimulation model.
Epilepsy research 2000;40(1):41-52.
2000: Anne-Marie Cleton; J Odman; Piet H van Der Graaf; W Ghijsen; Rob A Voskuyl; Meindert Danhof
Mechanism-based modeling of functional adaptation upon chronic treatment with midazolam.
Pharmaceutical research 2000;17(3):321-7.
1999: Anne-Marie Cleton; HJ de Greef; Peter M Edelbroek; Rob A Voskuyl; Meindert Danhof
Stereoselective central nervous system effects of the R- and S-isomers of the GABA uptake blocker N-(4, 4-di-(3-methylthien-2-yl)but-3-enyl) nipecotic acid in the rat.
British journal of pharmacology 1999;128(8):1651-8.
1999: Anne-Marie Cleton; Piet H van Der Graaf; W Ghijsen; Rob A Voskuyl; Meindert Danhof
Mechanism-based modeling of adaptive changes in the pharmacodynamics of midazolam in the kindling model of epilepsy.
Pharmaceutical research 1999;16(11):1702-9.
1999: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman; Rob A Voskuyl
The antiarrhythmic and anticonvulsant effects of dietary N-3 fatty acids.
The Journal of membrane biology 1999;172(1):1-11.
1999: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman; Rob A Voskuyl
Experimental studies on antiarrhythmic and antiseizure effects of polyunsaturated fatty acids in excitable tissues.
The Journal of nutritional biochemistry 1999;10(8):440-8.
1999: Anne-Marie Cleton; HJ de Greef; Peter M Edelbroek; Rob A Voskuyl; Meindert Danhof
Application of a combined "effect compartment/indirect response model" to the central nervous system effects of tiagabine in the rat.
Journal of pharmacokinetics and biopharmaceutics 1999;27(3):301-23.
1999: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman; Rob A Voskuyl
Functional and electrophysiologic effects of polyunsaturated fatty acids on exictable tissues: heart and brain.
Prostaglandins, leukotrienes, and essential fatty acids 1999;60(5-6):307-12.
1999: Anne-Marie Cleton; D Mazee; Rob A Voskuyl; Meindert Danhof
Rate of change of blood concentrations is a major determinant of the pharmacodynamics of midazolam in rats.
British journal of pharmacology 1999;127(1):227-35.
1998: OE Della Paschoa; MR Kruk; Rob A Voskuyl; Meindert Danhof
Effects of repeated seizure induction on seizure activity, post-ictal and interictal behavior.
Brain research 1998;814(1-2):199-208.
1998: OE Della Paschoa; Rob A Voskuyl; Meindert Danhof
Modelling of the pharmacodynamic interaction between phenytoin and sodium valproate.
British journal of pharmacology 1998;125(7):1610-6.
1998: OE Della Paschoa; MR Kruk; R Hamstra; Rob A Voskuyl; Meindert Danhof
Pharmacodynamic interaction between phenytoin and sodium valproate changes seizure thresholds and pattern.
British journal of pharmacology 1998;125(5):997-1004.
1998: Anne-Marie Cleton; Rob A Voskuyl; Meindert Danhof
Adaptive changes in the pharmacodynamics of midazolam in different experimental models of epilepsy: kindling, cortical stimulation and genetic absence epilepsy.
British journal of pharmacology 1998;125(4):615-20.
1998: OE Della Paschoa; JW Mandema; Rob A Voskuyl; Meindert Danhof
Pharmacokinetic-pharmacodynamic modeling of the anticonvulsant and electroencephalogram effects of phenytoin in rats.
The Journal of pharmacology and experimental therapeutics 1998;284(2):460-6.
1998: Rob A Voskuyl; M Vreugdenhil; Jing X Kang; Alexander Leaf
Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model.
European journal of pharmacology 1998;341(2-3):145-52.
1997: OE Della Paschoa; MR Kruk; R Hamstra; Rob A Voskuyl; Meindert Danhof
Seizure patterns in kindling and cortical stimulation models of experimental epilepsy.
Brain research 1997;770(1-2):221-7.
1996: A Hoogerkamp; R H Arends; A M Bomers; JW Mandema; Rob A Voskuyl; Meindert Danhof
Pharmacokinetic/pharmacodynamic relationship of benzodiazepines in the direct cortical stimulation model of anticonvulsant effect.
The Journal of pharmacology and experimental therapeutics 1996;279(2):803-12.
1996: Martin Vreugdenhil; C Bruehl; Rob A Voskuyl; Jing X Kang; Alexander Leaf; Wytse J Wadman
Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12559-63.
1994: R J Van den Berg; C A Versluys; A de Vos; Rob A Voskuyl
Nerve fiber size-related block of action currents by phenytoin in mammalian nerve.
Epilepsia 1994;35(6):1279-88.
1994: A Hoogerkamp; P W Vis; Meindert Danhof; Rob A Voskuyl
Characterization of the pharmacodynamics of several antiepileptic drugs in a direct cortical stimulation model of anticonvulsant effect in the rat.
The Journal of pharmacology and experimental therapeutics 1994;269(2):521-8.
1993: R J Van den Berg; P Kok; Rob A Voskuyl
Valproate and sodium currents in cultured hippocampal neurons.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1993;93(2):279-87.
1992: A M Stijnen; I Postel-Westra; MW Langemeijer; A Hoogerkamp; Rob A Voskuyl; C F van Bezooijen; Meindert Danhof
Pharmacodynamics of the anticonvulsant effect of oxazepam in aging BN/BiRij rats.
British journal of pharmacology 1992;107(1):165-70.
1992: Rob A Voskuyl; A Hoogerkamp; Meindert Danhof
Properties of the convulsive threshold determined by direct cortical stimulation in rats.
Epilepsy research 1992;12(2):111-20.
1990: J Dingemanse; Rob A Voskuyl; MW Langemeijer; I Postel-Westra; Douwe D Breimer; H Meinardi; Meindert Danhof
Pharmacokinetic-pharmacodynamic modelling of the anticonvulsant effect of oxazepam in individual rats.
British journal of pharmacology 1990;99(1):53-8.
1989: Rob A Voskuyl; J Dingemanse; Meindert Danhof
Determination of the threshold for convulsions by direct cortical stimulation.
Epilepsy research 1989;3(2):120-9.
1987: Rob A Voskuyl; Henk Albus
Enhancement of recurrent inhibition by angular bundle kindling is retained in hippocampal slices.
The International journal of neuroscience 1987;36(3-4):153-66.
1985: Rob A Voskuyl; Henk Albus
Spontaneous epileptiform discharges in hippocampal slices induced by 4-aminopyridine.
Brain research 1985;342(1):54-66.