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Ralf-Holger Voss

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Ralf-Holger Voss; Simone Thomas; Christina Pfirschke; Beate Hauptrock; Sebastian Klobuch; Jürgen Kuball; Margarete Grabowski; Renate Engel; Philippe Guillaume; Pedro Romero; Christoph Huber; Philipp Beckhove; Matthias Theobald
Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells.
Shao-An Xue; Liquan Gao; Sharyn Thomas; Daniel P Hart; John Zhao Xue; Roopinder Gillmore; Ralf-Holger Voss; Emma Morris; Hans J Stauss
Development of a Wilms' tumor antigen-specific T-cell receptor for clinical trials: engineered patient's T cells can eliminate autologous leukemia blasts in NOD/SCID mice.
Jürgen Kuball; Beate Hauptrock; Victoria Marcu (-Malina); Edite Antunes; Ralf-Holger Voss; Matthias Wolfl; Roland Strong; Matthias Theobald; Philip D Greenberg
Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.

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2010: Ralf-Holger Voss; Simone Thomas; Christina Pfirschke; Beate Hauptrock; Sebastian Klobuch; Jürgen Kuball; Margarete Grabowski; Renate Engel; Philippe Guillaume; Pedro Romero; Christoph Huber; Philipp Beckhove; Matthias Theobald
Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells.
Blood 2010;115(25):5154-63.
2010: Shao-An Xue; Liquan Gao; Sharyn Thomas; Daniel P Hart; John Zhao Xue; Roopinder Gillmore; Ralf-Holger Voss; Emma Morris; Hans J Stauss
Development of a Wilms' tumor antigen-specific T-cell receptor for clinical trials: engineered patient's T cells can eliminate autologous leukemia blasts in NOD/SCID mice.
Haematologica 2010;95(1):126-34.
2009: Jürgen Kuball; Beate Hauptrock; Victoria Marcu (-Malina); Edite Antunes; Ralf-Holger Voss; Matthias Wolfl; Roland Strong; Matthias Theobald; Philip D Greenberg
Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.
The Journal of experimental medicine 2009;206(2):463-75.
2008: Ralf-Holger Voss; Ralph A Willemsen; Jürgen Kuball; Margarete Grabowski; Renate Engel; Ratna S Intan; Philippe Guillaume; Pedro Romero; Christoph Huber; Matthias Theobald
Molecular design of the Calphabeta interface favors specific pairing of introduced TCRalphabeta in human T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):391-401.
2007: Jürgen Kuball; Michelle L Dossett; Matthias Wolfl; William Y Ho; Ralf-Holger Voss; Carla Fowler; Philip D Greenberg
Facilitating matched pairing and expression of TCR chains introduced into human T cells.
Blood 2007;109(6):2331-8.
2007: Peng H Tan; Shao-An Xue; Bin Wei; shao-an xue; Ralf-Holger Voss; Andrew J T George
Changing viral tropism using immunoliposomes alters the stability of gene expression: implications for viral vector design.
Molecular medicine (Cambridge, Mass.) 2007;13(3-4):216-26.
2006: Ralf-Holger Voss; Jürgen Kuball; Renate Engel; Philippe Guillaume; Pedro Romero; Christoph Huber; Matthias Theobald
Redirection of T cells by delivering a transgenic mouse-derived MDM2 tumor antigen-specific TCR and its humanized derivative is governed by the CD8 coreceptor and affects natural human TCR expression.
Immunologic research 2006;34(1):67-87.
2005: Jürgen Kuball; Frank W Schmitz; Ralf-Holger Voss; Edite Antunes Ferreira; Renate Engel; Philippe Guillaume; Susanne Strand; Pedro Romero; Christoph Huber; Linda A Sherman; Matthias Theobald
Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR.
Immunity 2005;22(1):117-29.
2005: Ralf-Holger Voss; Jürgen Kuball; Matthias Theobald
Designing TCR for cancer immunotherapy.
Methods in molecular medicine 2005;109():229-56.
2001: T Stanislawski; Ralf-Holger Voss; Carina Lotz; Elena Sadovnikova; Ralph A Willemsen; Jürgen Kuball; Thomas Ruppert; Reinder L H Bolhuis; Cornelis J M Melief; Christoph Huber; Hans J Stauss; Matthias Theobald
Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer.
Nature immunology 2001;2(10):962-70.
2000: Ralf-Holger Voss; Carina Lotz; A Cellary; Matthias Theobald
Targeting p53, hdm2, and CD19: vaccination and immunologic strategies.
Bone marrow transplantation 2000;25 Suppl 2():S43-5.