Mladen Vranic

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Bates Holly E; Sirek Adam; Kiraly Michael A; Yue Jessica T Y; Riddell Michael C; Matthews Stephen G; Vranic Mladen
Adaptation to intermittent stress promotes maintenance of beta-cell compensation: comparison with food restriction.
Inouye Karen E; Chan Owen; Yue Jessica T Y; Andrews Marcus; Li Qifu; Matthews Stephen G; Vranic Mladen
The effect of long-term insulin treatment with and without antecedent hypoglycemia on neuropeptide and corticosteroid receptor expression in the brains of diabetic rats.
Bates Holly E; Sirek Adam S; Kiràly Michael A; Yue Jessica T Y; Goche Montes Danitza; Matthews Stephen G; Vranic Mladen
Adaptation to mild, intermittent stress delays development of hyperglycemia in the Zucker diabetic Fatty rat independent of food intake: role of habituation of the hypothalamic-pituitary-adrenal axis.

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All Publications

2008: Bates Holly E; Sirek Adam; Kiraly Michael A; Yue Jessica T Y; Riddell Michael C; Matthews Stephen G; Vranic Mladen
Adaptation to intermittent stress promotes maintenance of beta-cell compensation: comparison with food restriction.
American journal of physiology. Endocrinology and metabolism 2008;295(4):E947-58.
2008: Inouye Karen E; Chan Owen; Yue Jessica T Y; Andrews Marcus; Li Qifu; Matthews Stephen G; Vranic Mladen
The effect of long-term insulin treatment with and without antecedent hypoglycemia on neuropeptide and corticosteroid receptor expression in the brains of diabetic rats.
Brain research bulletin 2008;77(4):149-57.
2008: Bates Holly E; Sirek Adam S; Kiràly Michael A; Yue Jessica T Y; Goche Montes Danitza; Matthews Stephen G; Vranic Mladen
Adaptation to mild, intermittent stress delays development of hyperglycemia in the Zucker diabetic Fatty rat independent of food intake: role of habituation of the hypothalamic-pituitary-adrenal axis.
Endocrinology 2008;149(6):2990-3001.
2008: Teodoro Tracy; Zhang Liling; Alexander Todd; Yue Jessica; Vranic Mladen; Volchuk Allen
Oleanolic acid enhances insulin secretion in pancreatic beta-cells.
FEBS letters 2008;582(9):1375-80.
2008: Zhang W-J; Tan Y-F; Yue J T Y; Vranic M; Wojtowicz J M
Impairment of hippocampal neurogenesis in streptozotocin-treated diabetic rats.
Acta neurologica Scandinavica 2008;117(3):205-10.
2008: Király Michael A; Bates Holly E; Kaniuk Natalia A; Yue Jessica T Y; Brumell John H; Matthews Stephen G; Riddell Michael C; Vranic Mladen
Swim training prevents hyperglycemia in ZDF rats: mechanisms involved in the partial maintenance of beta-cell function.
American journal of physiology. Endocrinology and metabolism 2008;294(2):E271-83.
2007: Bates Holly E; Kiraly Michael A; Yue Jessica T Y; Goche Montes Danitza; Elliott Melanie E; Riddell Michael C; Matthews Stephen G; Vranic Mladen
Recurrent intermittent restraint delays fed and fasting hyperglycemia and improves glucose return to baseline levels during glucose tolerance tests in the Zucker diabetic fatty rat--role of food intake and corticosterone.
Metabolism: clinical and experimental 2007;56(8):1065-75.
2007: Király Michael A; Bates Holly E; Yue Jessica T Y; Goche-Montes Danitza; Fediuc Sergiu; Park Edward; Matthews Stephen G; Vranic Mladen; Riddell Michael C
Attenuation of type 2 diabetes mellitus in the male Zucker diabetic fatty rat: the effects of stress and non-volitional exercise.
Metabolism: clinical and experimental 2007;56(6):732-44.
2007: Kaniuk Natalia A; Kiraly Michael; Bates Holly; Vranic Mladen; Volchuk Allen; Brumell John H
Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy.
Diabetes 2007;56(4):930-9.
2006: Klip Amira; Vranic Mladen
Muscle, liver, and pancreas: Three Musketeers fighting to control glycemia.
American journal of physiology. Endocrinology and metabolism 2006;291(6):E1141-3.
2006: Inouye Karen E; Yue Jessica T Y; Chan Owen; Kim Tony; Akirav Eitan M; Park Edward; Riddell Michael C; Burdett Elena; Matthews Stephen G; Vranic Mladen
Effects of insulin treatment without and with recurrent hypoglycemia on hypoglycemic counterregulation and adrenal catecholamine-synthesizing enzymes in diabetic rats.
Endocrinology 2006;147(4):1860-70.
2005: Park Edward; Chan Owen; Li Qifu; Kiraly Mike; Matthews Stephen G; Vranic Mladen; Riddell Michael C
Changes in basal hypothalamo-pituitary-adrenal activity during exercise training are centrally mediated.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(5):R1360-71.
2005: Chan Owen; Inouye Karen; Akirav Eitan M; Park Edward; Riddell Michael C; Matthews Stephen G; Vranic Mladen
Hyperglycemia does not increase basal hypothalamo-pituitary-adrenal activity in diabetes but it does impair the HPA response to insulin-induced hypoglycemia.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(1):R235-46.
2005: Chan Owen; Inouye Karen; Akirav Eitan; Park Edward; Riddell Michael C; Vranic Mladen; Matthews Stephen G
Insulin alone increases hypothalamo-pituitary-adrenal activity, and diabetes lowers peak stress responses.
Endocrinology 2005;146(3):1382-90.
2005: Inouye Karen E; Chan Owen; Yue Jessica T Y; Matthews Stephen G; Vranic Mladen
Effects of diabetes and recurrent hypoglycemia on the regulation of the sympathoadrenal system and hypothalamo-pituitary-adrenal axis.
American journal of physiology. Endocrinology and metabolism 2005;288(2):E422-9.
2004: Akirav Eitan M; Chan Owen; Inouye Karen; Riddell Michael C; Matthews Stephen G; Vranic Mladen
Partial leptin restoration increases hypothalamic-pituitary-adrenal activity while diminishing weight loss and hyperphagia in streptozotocin diabetic rats.
Metabolism: clinical and experimental 2004;53(12):1558-64.
2003: Kreisman Stuart H; Halter Jeffrey B; Vranic Mladen; Marliss Errol B
Combined infusion of epinephrine and norepinephrine during moderate exercise reproduces the glucoregulatory response of intense exercise.
Diabetes 2003;52(6):1347-54.
2003: Chan O; Inouye K; Riddell M C; Vranic M; Matthews S G
Diabetes and the hypothalamo-pituitary-adrenal (HPA) axis.
Minerva endocrinologica 2003;28(2):87-102.
2002: Inouye K; Chan O; Riddell M C; Akirav E; Matthews S G; Vranic M
Mechanisms of impaired hypothalamic-pituitary-adrenal (HPA) function in diabetes: reduced counterregulatory responsiveness to hypoglycaemia.
Diabetes, nutrition & metabolism 2002;15(5):348-55; discussion 355-6, 362.
2002: Chan Owen; Chan Stephen; Inouye Karen; Shum Kathy; Matthews Stephen G; Vranic Mladen
Diabetes impairs hypothalamo-pituitary-adrenal (HPA) responses to hypoglycemia, and insulin treatment normalizes HPA but not epinephrine responses.
Diabetes 2002;51(6):1681-9.
2002: Inouye Karen; Shum Kathy; Chan Owen; Mathoo Julian; Matthews Stephen G; Vranic Mladen
Effects of recurrent hyperinsulinemia with and without hypoglycemia on counterregulation in diabetic rats.
American journal of physiology. Endocrinology and metabolism 2002;282(6):E1369-79.
2002: Chan Owen; Inouye Karen; Vranic Mladen; Matthews Stephen G
Hyperactivation of the hypothalamo-pituitary-adrenocortical axis in streptozotocin-diabetes is associated with reduced stress responsiveness and decreased pituitary and adrenal sensitivity.
Endocrinology 2002;143(5):1761-8.
2002: Marliss Errol B; Vranic Mladen
Intense exercise has unique effects on both insulin release and its roles in glucoregulation: implications for diabetes.
Diabetes 2002;51 Suppl 1():S271-83.
2001: Chan O; Chan S; Inouye K; Vranic M; Matthews S G
Molecular regulation of the hypothalamo-pituitary-adrenal axis in streptozotocin-induced diabetes: effects of insulin treatment.
Endocrinology 2001;142(11):4872-9.
2001: Shum K; Inouye K; Chan O; Mathoo J; Bilinski D; Matthews S G; Vranic M
Effects of antecedent hypoglycemia, hyperinsulinemia, and excess corticosterone on hypoglycemic counterregulation.
American journal of physiology. Endocrinology and metabolism 2001;281(3):E455-65.
2001: Carpentier A; Patterson B W; Uffelman K D; Giacca A; Vranic M; Cattral M S; Lewis G F
The effect of systemic versus portal insulin delivery in pancreas transplantation on insulin action and VLDL metabolism.
Diabetes 2001;50(6):1402-13.
2001: Kreisman S H; Ah Mew N; Halter J B; Vranic M; Marliss E B
Norepinephrine infusion during moderate-intensity exercise increases glucose production and uptake.
The Journal of clinical endocrinology and metabolism 2001;86(5):2118-24.
2001: Fisher S J; Shi Z Q; Lickley H L; Efendic S; Vranic M; Giacca A
Low-dose IGF-I has no selective advantage over insulin in regulating glucose metabolism in hyperglycemic depancreatized dogs.
The Journal of endocrinology 2001;168(1):49-58.
2000: Niwa M; Rashid S; Shum K; Mathoo J M; Chan O; Tchipashvili V; Kawamori R; Vranic M; Giacca A
Effect of JTT-501 on net hepatic glucose balance and peripheral glucose uptake in alloxan-induced diabetic dogs.
Metabolism: clinical and experimental 2000;49(7):862-7.
2000: Kreisman S H; Ah Mew N; Arsenault M; Nessim S J; Halter J B; Vranic M; Marliss E B
Epinephrine infusion during moderate intensity exercise increases glucose production and uptake.
American journal of physiology. Endocrinology and metabolism 2000;278(5):E949-57.
2000: Kreisman S H; Manzon A; Nessim S J; Morais J A; Gougeon R; Fisher S J; Vranic M; Marliss E B
Glucoregulatory responses to intense exercise performed in the postprandial state.
American journal of physiology. Endocrinology and metabolism 2000;278(5):E786-93.
2000: Sigal R J; Fisher S J; Manzon A; Morais J A; Halter J B; Vranic M; Marliss E B
Glucoregulation during and after intense exercise: effects of alpha-adrenergic blockade.
Metabolism: clinical and experimental 2000;49(3):386-94.
2000: Rashid S; Shi Z Q; Niwa M; Mathoo J M; Vandelangeryt M L; Bilinski D; Lewis G F; Vranic M
Beta-blockade, but not normoglycemia or hyperinsulinemia, markedly diminishes stress-induced hyperglycemia in diabetic dogs.
Diabetes 2000;49(2):253-62.
2000: Marliss E B; Kreisman S H; Manzon A; Halter J B; Vranic M; Nessim S J
Gender differences in glucoregulatory responses to intense exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;88(2):457-66.
1999: Sigal R J; Fisher S J; Halter J B; Vranic M; Marliss E B
Glucoregulation during and after intense exercise: effects of beta-adrenergic blockade in subjects with type 1 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1999;84(11):3961-71.
1999: Lekas M C; Fisher S J; El-Bahrani B; van Delangeryt M; Vranic M; Shi Z Q
Glucose uptake during centrally induced stress is insulin independent and enhanced by adrenergic blockade.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;87(2):722-31.
1999: Mathoo J M; Shi Z Q; Klip A; Vranic M
Opposite effects of acute hypoglycemia and acute hyperglycemia on glucose transport and glucose transporters in perfused rat skeletal muscle.
Diabetes 1999;48(6):1281-8.
1999: Sandhu H; Wiesenthal S R; MacDonald P E; McCall R H; Tchipashvili V; Rashid S; Satkunarajah M; Irwin D M; Shi Z Q; Brubaker P L; Wheeler M B; Vranic M; Efendic S; Giacca A
Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs.
Diabetes 1999;48(5):1045-53.
1999: Lewis G F; Carpentier A; Bilinski D; Giacca A; Vranic M
Counterregulatory response to hypoglycemia differs according to the insulin delivery route, but does not affect glucose production in normal humans.
The Journal of clinical endocrinology and metabolism 1999;84(3):1037-46.
1999: Lewis G F; Carpentier A; Vranic M; Giacca A
Resistance to insulin's acute direct hepatic effect in suppressing steady-state glucose production in individuals with type 2 diabetes.
Diabetes 1999;48(3):570-6.
1999: Marette A; Dimitrakoudis D; Shi Q; Rodgers C D; Klip A; Vranic M
Glucose rapidly decreases plasma membrane GLUT4 content in rat skeletal muscle.
Endocrine 1999;10(1):13-8.
1998: Rodgers C D; Vranic M
Mediation of glucoregulation at rest and during exercise by the glucose-fatty acid cycle: in vivo and in vitro studies.
Canadian journal of applied physiology = Revue canadienne de physiologie appliquée 1998;23(6):534-57.
1998: Manzon A; Fisher S J; Morais J A; Lipscombe L; Guimond M C; Nessim S J; Sigal R J; Halter J B; Vranic M; Marliss E B
Glucose infusion partially attenuates glucose production and increases uptake during intense exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;85(2):511-24.
1998: Lewis G F; Vranic M; Giacca A
Role of free fatty acids and glucagon in the peripheral effect of insulin on glucose production in humans.
The American journal of physiology 1998;275(1 Pt 1):E177-86.
1997: Rastogi K S; Cooper R L; Shi Z Q; Vranic M
Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: effects of phlorizin treatment.
Endocrine 1997;7(3):367-75.
1997: Fisher S J; Lekas M; Shi Z Q; Bilinski D; Carvalho G; Giacca A; Vranic M
Insulin-independent acute restoration of euglycemia normalizes the impaired glucose clearance during exercise in diabetic dogs.
Diabetes 1997;46(11):1805-12.
1997: Lewis G F; Vranic M; Harley P; Giacca A
Fatty acids mediate the acute extrahepatic effects of insulin on hepatic glucose production in humans.
Diabetes 1997;46(7):1111-9.
1997: Lewis G F; Vranic M; Giacca A
Glucagon enhances the direct suppressive effect of insulin on hepatic glucose production in humans.
The American journal of physiology 1997;272(3 Pt 1):E371-8.
1997: Giacca A; Fisher S J; McCall R H; Shi Z Q; Vranic M
Direct and indirect effects of insulin in suppressing glucose production in depancreatized dogs: role of glucagon.
Endocrinology 1997;138(3):999-1007.
1997: Matsuhisa M; Shi Z Q; Wan C; Lekas M; Rodgers C D; Giacca A; Kawamori R; Vranic M
The effect of pioglitazone on hepatic glucose uptake measured with indirect and direct methods in alloxan-induced diabetic dogs.
Diabetes 1997;46(2):224-31.
1996: Shi Z Q; Rastogi K S; Lekas M; Efendic S; Drucker D J; Vranic M
Glucagon response to hypoglycemia is improved by insulin-independent restoration of normoglycemia in diabetic rats.
Endocrinology 1996;137(8):3193-9.
1996: Fisher S J; Shi Z Q; Lickley H L; Efendic S; Vranic M; Giacca A
A moderate decline in specific activity does not lead to an underestimation of hepatic glucose production during a glucose clamp.
Metabolism: clinical and experimental 1996;45(5):587-93.
1996: Fisher S J; Lekas M C; McCall R H; Shi Z Q; Giacca A; Vranic M
Determinants of glucose turnover in the pathophysiology of diabetes: an in vivo analysis in diabetic dogs.
Diabetes & metabolism 1996;22(2):111-21.
1996: Lewis G F; Zinman B; Groenewoud Y; Vranic M; Giacca A
Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans.
Diabetes 1996;45(4):454-62.
1996: Tsakiridis T; Wong P P; Liu Z; Rodgers C D; Vranic M; Klip A
Exercise increases the plasma membrane content of the Na+ -K+ pump and its mRNA in rat skeletal muscles.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;80(2):699-705.
1995: Tsakiridis T; McDowell H E; Walker T; Downes C P; Hundal H S; Vranic M; Klip A
Multiple roles of phosphatidylinositol 3-kinase in regulation of glucose transport, amino acid transport, and glucose transporters in L6 skeletal muscle cells.
Endocrinology 1995;136(10):4315-22.
1995: Tsakiridis T; Vranic M; Klip A
Phosphatidylinositol 3-kinase and the actin network are not required for the stimulation of glucose transport caused by mitochondrial uncoupling: comparison with insulin action.
The Biochemical journal 1995;309 ( Pt 1)():1-5.
1994: Tsakiridis T; Vranic M; Klip A
Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane.
The Journal of biological chemistry 1994;269(47):29934-42.
1994: Shi Z Q; Giacca A; Fisher S; Vidal H; van de Werve G; Vranic M
Importance of substrate changes in the decrease of hepatic glucose cycling during insulin infusion and declining glycemia in the depancreatized dog.
Diabetes 1994;43(11):1284-90.
1994: Miles P D; Yamatani K; Brown M R; Lickley H L; Vranic M
Intracerebroventricular administration of somatostatin octapeptide counteracts the hormonal and metabolic responses to stress in normal and diabetic dogs.
Metabolism: clinical and experimental 1994;43(9):1134-43.
1994: Giacca A; Fisher S J; Shi Z Q; Gupta R; Lickley H L; Skottner A; Anderson G H; Efendic S; Vranic M
Insulin-like growth factor-I and insulin have no differential effects on glucose production and utilization under conditions of hyperglycemia.
Endocrinology 1994;134(5):2251-8.
1993: Rastogi K S; Brubaker P L; Kawasaki A; Efendic S; Vranic M
Increase in somatostatin to glucagon ratio in islets of alloxan-diabetic dogs: effect of insulin-induced euglycemia.
Canadian journal of physiology and pharmacology 1993;71(7):512-7.
1993: Shi Z Q; Giacca A; Yamatani K; Fisher S J; Lickley H L; Vranic M
Effects of subbasal insulin infusion on resting and exercise-induced glucose turnover in depancreatized dogs.
The American journal of physiology 1993;264(3 Pt 1):E334-41.
1993: Lavoie L; Dimitrakoudis D; Marette A; Annabi B; Klip A; Vranic M; van de Werve G
Opposite effects of hyperglycemia and insulin deficiency on liver glycogen synthase phosphatase activity in the diabetic rat.
Diabetes 1993;42(2):363-6.
1993: Shi Z Q; Giacca A; Fisher S J; Lekas M; Bilinski D; Van Delangeryt M; Lickley H L; Vranic M
Indirect effects of insulin in regulating glucose fluxes.
Advances in experimental medicine and biology 1993;334():151-68.
1992: Marette A; Burdett E; Douen A; Vranic M; Klip A
Insulin induces the translocation of GLUT4 from a unique intracellular organelle to transverse tubules in rat skeletal muscle.
Diabetes 1992;41(12):1562-9.
1992: Dimitrakoudis D; Vranic M; Klip A
Effects of hyperglycemia on glucose transporters of the muscle: use of the renal glucose reabsorption inhibitor phlorizin to control glycemia.
Journal of the American Society of Nephrology : JASN 1992;3(5):1078-91.
1992: Klip A; Marette A; Dimitrakoudis D; Ramlal T; Giacca A; Shi Z Q; Vranic M
Effect of diabetes on glucoregulation. From glucose transporters to glucose metabolism in vivo.
Diabetes care 1992;15(11):1747-66.
1992: Giacca A; Fisher S J; Shi Z Q; Gupta R; Lickley H L; Vranic M
Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs.
The Journal of clinical investigation 1992;90(5):1769-77.
1992: Yamatani K; Shi Z Q; Giacca A; Gupta R; Fisher S; Lickley H L; Vranic M
Role of FFA-glucose cycle in glucoregulation during exercise in total absence of insulin.
The American journal of physiology 1992;263(4 Pt 1):E646-53.
1992: Vranic M
Banting Lecture: glucose turnover. A key to understanding the pathogenesis of diabetes (indirect effects of insulin).
Diabetes 1992;41(9):1188-206.
1992: Marette A; Richardson J M; Ramlal T; Balon T W; Vranic M; Pessin J E; Klip A
Abundance, localization, and insulin-induced translocation of glucose transporters in red and white muscle.
The American journal of physiology 1992;263(2 Pt 1):C443-52.
1992: Finegood D T; Miles P D; Lickley H L; Vranic M
Estimation of glucose production during exercise with a one-compartment variable-volume model.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(6):2501-9.
1992: Miles P D; Finegood D T; Lickley H L; Vranic M
Regulation of glucose turnover at the onset of exercise in the dog.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(6):2487-94.
1992: Dimitrakoudis D; Ramlal T; Rastogi S; Vranic M; Klip A
Glycaemia regulates the glucose transporter number in the plasma membrane of rat skeletal muscle.
The Biochemical journal 1992;284 ( Pt 2)():341-8.
1991: Brubaker P L; Kazumi T; Hirano T; Vranic M; Steiner G
Failure of chronic hyperinsulinemia to suppress pancreatic glucagon in vivo in the rat.
Canadian journal of physiology and pharmacology 1991;69(3):437-43.
1991: Miles P D; Yamatani K; Lickley H L; Vranic M
Mechanism of glucoregulatory responses to stress and their deficiency in diabetes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1296-300.
1991: Douen A G; Burdett E; Ramlal T; Rastogi S; Vranic M; Klip A
Characterization of glucose transporter-enriched membranes from rat skeletal muscle: assessment of endothelial cell contamination and presence of sarcoplasmic reticulum and transverse tubules.
Endocrinology 1991;128(1):611-6.
1991: Vranic M; Miles P; Rastogi K; Yamatani K; Shi Z; Lickley L; Hetenyi G
Effect of stress on glucoregulation in physiology and diabetes.
Advances in experimental medicine and biology 1991;291():161-83.
1990: Douen A G; Ramlal T; Rastogi S; Bilan P J; Cartee G D; Vranic M; Holloszy J O; Klip A
Exercise induces recruitment of the "insulin-responsive glucose transporter". Evidence for distinct intracellular insulin- and exercise-recruitable transporter pools in skeletal muscle.
The Journal of biological chemistry 1990;265(23):13427-30.
1990: Giacca A; Gupta R; Efendic S; Hall K; Skottner A; Lickley L; Vranic M
Differential effects of IGF-I and insulin on glucoregulation and fat metabolism in depancreatized dogs.
Diabetes 1990;39(3):340-7.
1990: Rastogi K S; Lickley L; Jokay M; Efendic S; Vranic M
Paradoxical reduction in pancreatic glucagon with normalization of somatostatin and decrease in insulin in normoglycemic alloxan-diabetic dogs: a putative mechanism of glucagon irresponsiveness to hypoglycemia.
Endocrinology 1990;126(2):1096-104.
1989: Ramlal T; Rastogi S; Vranic M; Klip A
Decrease in glucose transporter number in skeletal muscle of mildly diabetic (streptozotocin-treated) rats.
Endocrinology 1989;125(2):890-7.
1989: Hetenyi G; Gauthier C; Byers M; Vranic M
Phlorizin-induced normoglycemia partially restores glucoregulation in diabetic dogs.
The American journal of physiology 1989;256(2 Pt 1):E277-83.
1988: Finegood D T; Bergman R N; Vranic M
Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps.
Diabetes 1988;37(8):1025-34.
1988: Bjorkman O; Miles P; Wasserman D; Lickley L; Vranic M
Regulation of glucose turnover during exercise in pancreatectomized, totally insulin-deficient dogs. Effects of beta-adrenergic blockade.
The Journal of clinical investigation 1988;81(6):1759-67.
1987: el-Tayeb K M; Vranic M; Brubaker P L; Lickley H L
Beta endorphin modulation of the glucoregulatory effects of repeated epinephrine infusion in alloxan-diabetic and normal dogs.
Diabetologia 1987;30(9):745-54.
1987: Lickley H L; Kemmer F W; el-Tayeb K M; Vranic M
Importance of glucagon in the control of futile cycling as studied in alloxan-diabetic dogs.
Diabetologia 1987;30(3):175-82.
1987: Rastogi K S; Efendic S; Lickley L; Kovacevic N; Vranic M
Elevated somatostatin in pancreatic islets of adrenalectomized dogs.
Endocrinology 1987;120(2):544-8.
1986: Gauthier C; el-Tayeb K; Vranic M; Lickley H L
Glucoregulatory role of cortisol and epinephrine interactions studied in adrenalectomized dogs.
The American journal of physiology 1986;250(4 Pt 1):E393-401.
1986: el-Tayeb K M; Brubaker P L; Lickley H L; Cook E; Vranic M
Effect of opiate-receptor blockade on normoglycemic and hypoglycemic glucoregulation.
The American journal of physiology 1986;250(3 Pt 1):E236-42.
1986: el-Tayeb K M; Gauthier C J; Brubaker P L; Lickley H L; Vranic M
Hormonal and metabolic responses to intracarotid and intrajugular infusion of beta-endorphin in normal dogs.
Canadian journal of physiology and pharmacology 1986;64(3):306-10.
1986: Lussier B; Vranic M; Kovacevic N; Hetenyi G
Glucoregulation in alloxan-diabetic dogs.
Metabolism: clinical and experimental 1986;35(1):18-24.
1985: el-Tayeb K M; Brubaker P L; Vranic M; Lickley H L
Beta-endorphin modulation of the glucoregulatory effects of repeated epinephrine infusion in normal dogs.
Diabetes 1985;34(12):1293-300.
1985: Lussier B; Vranic M; Gauthier C; Hetenyi G
Glucoregulation in dogs treated with methyl-prednisolone.
Metabolism: clinical and experimental 1985;34(10):906-11.
1984: Vranic M; Gauthier C; Bilinski D; Wasserman D; El Tayeb K; Hetenyi G; Lickley H L
Catecholamine responses and their interactions with other glucoregulatory hormones.
The American journal of physiology 1984;247(2 Pt 1):E145-56.
1983: Lickley H L; Kemmer F W; Doi K; Vranic M
Glucagon suppression improves glucoregulation in moderate but not chronic severe diabetes.
The American journal of physiology 1983;245(4):E424-9.
1983: Gauthier C; Vranic M; Hetenyi G
Nonhypoglycemic glucoregulation: role of glycerol and glucoregulatory hormones.
The American journal of physiology 1983;244(4):E373-9.
1983: Kemmer F W; Sirek A; Sirek O V; Perez G; Vranic M
Glucoregulatory mechanisms following hypophysectomy in diabetic dogs with residual insulin secretion.
Diabetes 1983;32(1):26-34.
1982: Kemmer F W; Lickley H L; Gray D E; Perez G; Vranic M
State of metabolic control determines role of epinephrine-glucagon interaction in glucoregulation in diabetes.
The American journal of physiology 1982;242(6):E428-36.
1981: Perez G; Kemmer F W; Lickley H L; Vranic M
Importance of glucagon in mediating epinephrine-induced hyperglycemia in alloxan-diabetic dogs.
The American journal of physiology 1981;241(4):E328-35.
1981: Lickley H L; Kemmer F W; Gray D E; Kovacevic N; Hatton T W; Perez G; Vranic M
Chromatographic pattern of extrapancreatic glucagon and glucagon-like immunoreactivity before and during stimulation by epinephrine and participation of glucagon in epinephrine-induced hepatic glucose overproduction.
Surgery 1981;90(2):186-94.
1980: Gauthier C; Vranic M; Hetenyi G
Importance of glucagon in regulatory rather than emergency responses to hypoglycemia.
The American journal of physiology 1980;238(2):E131-40.

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Mladen Vranic

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