FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Grégoire Vuagniaux

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Co-author Network

Publications

TOP 3
Philippe A Gallay; Roger G Ptak; Michael D Bobardt; Jean-Maurice Dumont; Grégoire Vuagniaux; Brigitte Rosenwirth
Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphisms.
Adriaan H de Wilde; Ying Fang; Yanhua Li; Robert Lysek; Eric J Snijder; Yvonne van der Meer; Grégoire Vuagniaux; Martijn J van Hemert
Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis.
Giovanni Quarato; Grégoire Vuagniaux; Nazzareno Capitanio; Annamaria D'Aprile; Bruno Gavillet; Darius Moradpour; Claudia Piccoli
The cyclophilin inhibitor alisporivir prevents hepatitis C virus-mediated mitochondrial dysfunction.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Grégoire Vuagniaux (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Philippe A Gallay; Roger G Ptak; Michael D Bobardt; Jean-Maurice Dumont; Grégoire Vuagniaux; Brigitte Rosenwirth
Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphisms.
Viruses 2013;5(3):981-97.
2013: Adriaan H de Wilde; Ying Fang; Yanhua Li; Robert Lysek; Eric J Snijder; Yvonne van der Meer; Grégoire Vuagniaux; Martijn J van Hemert
Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis.
Journal of virology 2013;87(3):1454-64.
2012: Giovanni Quarato; Grégoire Vuagniaux; Nazzareno Capitanio; Annamaria D'Aprile; Bruno Gavillet; Darius Moradpour; Claudia Piccoli
The cyclophilin inhibitor alisporivir prevents hepatitis C virus-mediated mitochondrial dysfunction.
Hepatology (Baltimore, Md.) 2012;55(5):1333-43.
2010: Erin R Wissing; Douglas P Millay; Grégoire Vuagniaux; Jeffery D Molkentin
Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice.
Neuromuscular disorders : NMD 2010;20(11):753-60.
2010: Isabelle Landrieu; Xavier Hanoulle; Fanny Bonachera; Arnaud Hamel; nathalie sibille; Yanxia Yin; Jean-Michel Wieruszeski; Dragos Horvath; Qun Wei; Grégoire Vuagniaux; Guy Lippens
Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025.
Biochemistry 2010;49(22):4679-86.
2010: Lotte Coelmont; Xavier Hanoulle; Udayan Chatterji; Carola Berger; Joke Snoeck; Michael Bobardt; Precious Lim; Inge Vliegen; Jan Paeshuyse; Grégoire Vuagniaux; Anne-Mieke Vandamme; Ralf Bartenschlager; Philippe Gallay; Guy Lippens; Johan Neyts
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A.
PloS one 2010;5(10):e13687.
2010: Virginie Prulière-Escabasse; Christine Clerici; Grégoire Vuagniaux; Andre Coste; Estelle Escudier; Carole Planès
Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells.
Respiratory research 2010;11():141.
2010: Carole Planès; Nadia H Randrianarison; Roch-Philippe Charles; Simona Frateschi; Françoise Cluzeaud; Grégoire Vuagniaux; Paul Soler; Christine Clerici; Bernard C Rossier; Edith Hummler
ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1.
EMBO molecular medicine 2010;2(1):26-37.
2009: Lotte Coelmont; Suzanne Kaptein; Jan Paeshuyse; Inge Vliegen; Jean-Maurice Dumont; Grégoire Vuagniaux; Johan Neyts
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.
Antimicrobial agents and chemotherapy 2009;53(3):967-76.
2009: Raf Crabbé; Grégoire Vuagniaux; Jean-Maurice Dumont; Valérie Nicolas-Métral; Judith Marfurt; Laura Novaroli
An evaluation of the cyclophilin inhibitor Debio 025 and its potential as a treatment for chronic hepatitis C.
Expert opinion on investigational drugs 2009;18(2):211-20.
2009: Laure Delavallée; Luca Semerano; Eric Assier; Géraldine Vogel; Grégoire Vuagniaux; Marion Laborie; Daniel Zagury; Natacha Bessis; Marie-Christophe Boissier
Active immunization to tumor necrosis factor-alpha is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis.
Arthritis research & therapy 2009;11(6):R195.
2008: Douglas P Millay; Michelle A Sargent; Hanna Osinska; Christopher P Baines; Elisabeth R Barton; Grégoire Vuagniaux; H Lee Sweeney; Jeffrey Robbins; Jeffery D Molkentin
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.
Nature medicine 2008;14(4):442-7.
2007: Ludovic Gomez; Hélène Thibault; Adbdallah Gharib; Jean-Maurice Dumont; Grégoire Vuagniaux; Pietro Scalfaro; Geneviève Derumeaux; Michel Ovize
Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice.
American journal of physiology. Heart and circulatory physiology 2007;293(3):H1654-61.
2007: Michael Harris; Dmitri Firsov; Grégoire Vuagniaux; Monroe Stutts; Bernard C Rossier
A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes.
The Journal of biological chemistry 2007;282(1):58-64.
2006: Ditte Andreasen; Grégoire Vuagniaux; Nicole Fowler Jaeger; Edith Hummler; Bernard C Rossier
Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1.
Journal of the American Society of Nephrology : JASN 2006;17(4):968-76.
2005: Carole Planès; Céline Leyvraz; Tokujiro Uchida; Milena Apostolova Angelova; Grégoire Vuagniaux; Edith Hummler; Michael A Matthay; Christine Clerici; Bernard C Rossier
In vitro and in vivo regulation of transepithelial lung alveolar sodium transport by serine proteases.
American journal of physiology. Lung cellular and molecular physiology 2005;288(6):L1099-109.
2002: Michel Guipponi; Grégoire Vuagniaux; Marie Wattenhofer; Kazunori Shibuya; Maria Vazquez; Loretta Dougherty; Nathalie Scamuffa; Elizabeth Guida; Michiyo Okui; Colette Rossier; Manuela Hancock; Karine Buchet; Alexandre Reymond; Edith Hummler; Phillip L Marzella; Jun Kudoh; Nobuyoshi Shimizu; Hamish Scott; Stylianos E Antonarakis; Bernard C Rossier
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro.
Human molecular genetics 2002;11(23):2829-36.
2002: Grégoire Vuagniaux; Véronique Vallet; Nicole Fowler Jaeger; Edith Hummler; Bernard C Rossier
Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes.
The Journal of general physiology 2002;120(2):191-201.
2002: Isabelle Rubera; Evelyne Meier; Grégoire Vuagniaux; Anne-Marie Mérillat; Friedrich Beermann; Bernard C Rossier; Edith Hummler
A conditional allele at the mouse channel activating protease 1 (Prss8) gene locus.
Genesis (New York, N.Y. : 2000) 2002;32(2):173-6.
2000: Grégoire Vuagniaux; Véronique Vallet; Nicole Fowler Jaeger; Corinne Pfister; Marcelle Bens; Nicolette Farman; Nathalie Courtois-Coutry; Alain Vandewalle; Bernard C Rossier; Edith Hummler
Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line.
Journal of the American Society of Nephrology : JASN 2000;11(5):828-34.