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Kenneth Wagner

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Yalikun Suofu; Kenneth R Wagner; J P Broderick; J F Clark; Y Kurosawa; Aigang Lu
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Yalikun Suofu; Joseph Clark; Joseph Broderick; Kenneth R Wagner; Thomas Tomsick; ya_lian sa; Aigang Lu
Peroxynitrite decomposition catalyst prevents matrix metalloproteinase activation and neurovascular injury after prolonged cerebral ischemia in rats.
Aigang Lu; Joseph F Clark; Ruiqiong Ran; Gail Pyne-Geithman; Kenneth R Wagner; David E Millhorn; Frank R Sharp
Down-regulation of interleukin 7 mRNA by hypoxia is calcium dependent.

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All Publications

2012: Yalikun Suofu; Kenneth R Wagner; J P Broderick; J F Clark; Y Kurosawa; Aigang Lu
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Neuroscience 2012;212():180-9.
2010: Yalikun Suofu; Joseph Clark; Joseph Broderick; Kenneth R Wagner; Thomas Tomsick; ya_lian sa; Aigang Lu
Peroxynitrite decomposition catalyst prevents matrix metalloproteinase activation and neurovascular injury after prolonged cerebral ischemia in rats.
Journal of neurochemistry 2010;115(5):1266-76.
2009: Aigang Lu; Joseph F Clark; Ruiqiong Ran; Gail Pyne-Geithman; Kenneth R Wagner; David E Millhorn; Frank R Sharp
Down-regulation of interleukin 7 mRNA by hypoxia is calcium dependent.
Neurological research 2009;31(5):545-9.
2009: Aigang Lu; Joseph F Clark; Joseph P Broderick; Gail J Pyne-Geithman; Kenneth R Wagner; Pooja Khatri; Thomas A Tomsick; Frank R Sharp
Mechanical reperfusion is associated with post-ischemic hemorrhage in rat brain.
Experimental neurology 2009;216(2):407-12.
2008: Huichun Xu; Yang Tang; Da-Zhi Liu; Ruiqiong Ran; Bradley P Ander; Michelle Apperson; Xin She Liu; Jane C Khoury; Jeffrey P Gregg; Arthur Pancioli; Edward Jauch; Kenneth R Wagner; Piero Verro; Joseph P Broderick; Frank R Sharp
Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(7):1320-8.
2008: Aigang Lu; Joseph F Clark; Joseph P Broderick; Gail J Pyne-Geithman; Kenneth R Wagner; Ruiqiong Ran; Pooja Khatri; Thomas A Tomsick; Frank R Sharp
Reperfusion activates metalloproteinases that contribute to neurovascular injury.
Experimental neurology 2008;210(2):549-59.
2008: J F Clark; Matthew C Loftspring; W L Wurster; Shauna Beiler; C Beiler; Kenneth R Wagner; Gail J Pyne-Geithman
Bilirubin oxidation products, oxidative stress, and intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2008;105():7-12.
2007: Matthew C Loftspring; Joseph F Clark; Kenneth R Wagner
A novel duplex ELISA method for quantitation of plasma proteins in areas of brain edema.
Brain research 2007;1162():130-2.
2007: George J Shaw; Ashima Dhamija; Nazli Bavani; Kenneth R Wagner; Christy K Holland
Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis.
Physics in medicine and biology 2007;52(11):2953-67.
2007: Kenneth R Wagner
Modeling intracerebral hemorrhage: glutamate, nuclear factor-kappa B signaling and cytokines.
Stroke; a journal of cerebral circulation 2007;38(2 Suppl):753-8.
2006: Matthew C Loftspring; Shauna Beiler; Christian Beiler; Kenneth R Wagner
Plasma proteins in edematous white matter after intracerebral hemorrhage confound immunoblots: an ELISA to quantify contamination.
Journal of neurotrauma 2006;23(12):1904-11.
2006: Yang Tang; Huichun Xu; XinLi Du; Lisa Lit; Wynn Walker; Aigang Lu; Ruiqiong Ran; Jeffrey P Gregg; Melinda Reilly; Art Pancioli; Jane C Khoury; Laura Sauerbeck; Janice Carrozzella; Judith Spilker; Joseph Clark; Kenneth R Wagner; Edward Jauch; Dongwoo J Chang; Piero Verro; Joseph P Broderick; Frank R Sharp
Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(8):1089-102.
2006: Aigang Lu; Yang Tang; Ruiqiong Ran; Timothy L Ardizzone; Kenneth R Wagner; Frank R Sharp
Brain genomics of intracerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(2):230-52.
2006: Kenneth R Wagner; Shauna Beiler; C Beiler; John Kirkman; K Casey; T Robinson; D Larnard; Gabrielle M De Courten-Myers; Michael J Linke; Mario Zuccarello
Delayed profound local brain hypothermia markedly reduces interleukin-1beta gene expression and vasogenic edema development in a porcine model of intracerebral hemorrhage.
Acta neurochirurgica. Supplement 2006;96():177-82.
2005: Kenneth R Wagner; Christopher Dean; Shauna Beiler; David W Bryan; Benjamin A Packard; A George Smulian; Michael J Linke; Gabrielle M De Courten-Myers
Plasma infusions into porcine cerebral white matter induce early edema, oxidative stress, pro-inflammatory cytokine gene expression and DNA fragmentation: implications for white matter injury with increased blood-brain-barrier permeability.
Current neurovascular research 2005;2(2):149-55.
2005: Kenneth R Wagner; Mario Zuccarello
Local brain hypothermia for neuroprotection in stroke treatment and aneurysm repair.
Neurological research 2005;27(3):238-45.
2004: Chad J Morgan; Gail J Pyne-Geithman; Edward Jauch; Rakesh Shukla; Kenneth R Wagner; Joseph F Clark; Mario Zuccarello
Bilirubin as a cerebrospinal fluid marker of sentinel subarachnoid hemorrhage: a preliminary report in pigs.
Journal of neurosurgery 2004;101(6):1026-9.
2004: Timothy D Ardizzone; Aigang Lu; Kenneth R Wagner; Yang Tang; Ruiqiong Ran; Frank R Sharp
Glutamate receptor blockade attenuates glucose hypermetabolism in perihematomal brain after experimental intracerebral hemorrhage in rat.
Stroke; a journal of cerebral circulation 2004;35(11):2587-91.
2004: Kenneth R Wagner; Edward Jauch
Extending the window for acute stroke treatment: thrombolytics plus CNS protective therapies.
Experimental neurology 2004;188(2):195-9.
2004: Kenneth R Wagner; Barney E Dwyer
Hematoma removal, heme, and heme oxygenase following hemorrhagic stroke.
Annals of the New York Academy of Sciences 2004;1012():237-51.
2003: Kenneth R Wagner; Frank R Sharp; Timothy D Ardizzone; Aigang Lu; Joseph F Clark
Heme and iron metabolism: role in cerebral hemorrhage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(6):629-52.
2002: Norberto Andaluz; Mario Zuccarello; Kenneth R Wagner
Experimental animal models of intracerebral hemorrhage.
Neurosurgery clinics of North America 2002;13(3):385-93.
2002: Mario Zuccarello; Norberto Andaluz; Kenneth R Wagner
Minimally invasive therapy for intracerebral hematomas.
Neurosurgery clinics of North America 2002;13(3):349-54.
2002: Yang Tang; Aigang Lu; Bruce Aronow; Kenneth R Wagner; Frank R Sharp
Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia.
The European journal of neuroscience 2002;15(12):1937-52.
2002: Kenneth R Wagner; Benjamin A Packard; Cathy L Hall; A George Smulian; Michael J Linke; Gabrielle M De Courten-Myers; Lori M Packard; Nathan C Hall
Protein oxidation and heme oxygenase-1 induction in porcine white matter following intracerebral infusions of whole blood or plasma.
Developmental neuroscience 2002;24(2-3):154-60.
2001: Frank R Sharp; Myriam Bernaudin; M Bartels; Kenneth R Wagner
Glial expression of heat shock proteins (HSPs) and oxygen-regulated proteins (ORPs).
Progress in brain research 2001;132():427-40.
2000: N C Hall; Benjamin A Packard; C L Hall; Gabrielle M De Courten-Myers; Kenneth R Wagner
Protein oxidation and enzyme susceptibility in white and gray matter with in vitro oxidative stress: relevance to brain injury from intracerebral hemorrhage.
Cellular and molecular biology (Noisy-le-Grand, France) 2000;46(3):673-83.
2000: Kenneth R Wagner; Ya Hua; Gabrielle M De Courten-Myers; Joseph P Broderick; RN Nishimura; SY Lu; Barney E Dwyer
Tin-mesoporphyrin, a potent heme oxygenase inhibitor, for treatment of intracerebral hemorrhage: in vivo and in vitro studies.
Cellular and molecular biology (Noisy-le-Grand, France) 2000;46(3):597-608.
2000: Gabrielle M De Courten-Myers; Guohua Xi; J H Hwang; R Scott Dunn; A S Mills; Scott K Holland; Kenneth R Wagner; RE Myers
Hypoglycemic brain injury: potentiation from respiratory depression and injury aggravation from hyperglycemic treatment overshoots.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(1):82-92.
1999: J Howard James; Kenneth R Wagner; Jy-Kung King; R E Leffler; RK Upputuri; Ambikaipakan Balasubramaniam; Lou Ann Friend; Daniel Shelly; Richard J Paul; Josef E Fischer
Stimulation of both aerobic glycolysis and Na(+)-K(+)-ATPase activity in skeletal muscle by epinephrine or amylin.
The American journal of physiology 1999;277(1 Pt 1):E176-86.
1999: Kenneth R Wagner; Guohua Xi; Ya Hua; Mario Zuccarello; Gabrielle M De Courten-Myers; Joseph P Broderick; Thomas G Brott
Ultra-early clot aspiration after lysis with tissue plasminogen activator in a porcine model of intracerebral hemorrhage: edema reduction and blood-brain barrier protection.
Journal of neurosurgery 1999;90(3):491-8.
1998: Guohua Xi; Kenneth R Wagner; Richard F Keep; Ya Hua; Gabrielle M De Courten-Myers; Joseph P Broderick; Thomas G Brott; J T Hoff
Role of blood clot formation on early edema development after experimental intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 1998;29(12):2580-6.
1998: Gabrielle M De Courten-Myers; M Kleinholz; Kenneth R Wagner; RE Myers
Stroke assessment: morphometric infarct size versus neurologic deficit.
Journal of neuroscience methods 1998;83(2):151-7.
1998: Kenneth R Wagner; Guohua Xi; Ya Hua; M Kleinholz; Gabrielle M De Courten-Myers; RE Myers
Early metabolic alterations in edematous perihematomal brain regions following experimental intracerebral hemorrhage.
Journal of neurosurgery 1998;88(6):1058-65.
1996: Kenneth R Wagner; Guohua Xi; Ya Hua; M Kleinholz; Gabrielle M De Courten-Myers; R E Myers; J P Broderick; T G Brott
Lobar intracerebral hemorrhage model in pigs: rapid edema development in perihematomal white matter.
Stroke; a journal of cerebral circulation 1996;27(3):490-7.
1996: Gabrielle M De Courten-Myers; Kenneth R Wagner; R E Myers
Insulin reduction of cerebral infarction.
Journal of neurosurgery 1996;84(1):146-8.
1994: Gabrielle M De Courten-Myers; M Kleinholz; Kenneth R Wagner; R E Myers
Normoglycemia (not hypoglycemia) optimizes outcome from middle cerebral artery occlusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(2):227-36.
1994: Gabrielle M De Courten-Myers; M Kleinholz; Kenneth R Wagner; Guohua Xi; R E Myers
Efficacious experimental stroke treatment with high-dose methylprednisolone.
Stroke; a journal of cerebral circulation 1994;25(2):487-92; discussion 493.
1992: Gabrielle M De Courten-Myers; Kenneth R Wagner
Stroke models: strengths and pitfalls.
Resuscitation 1992;23(2):91-100.
1992: Kenneth R Wagner; M Kleinholz; Gabrielle M De Courten-Myers; R E Myers
Hyperglycemic versus normoglycemic stroke: topography of brain metabolites, intracellular pH, and infarct size.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(2):213-22.
1992: Gabrielle M De Courten-Myers; M Kleinholz; P Holm; GW Devoe; G Schmitt; Kenneth R Wagner; R E Myers
Hemorrhagic infarct conversion in experimental stroke.
Annals of emergency medicine 1992;21(2):120-6.
1991: U Angerås; M Hall-Angerås; Kenneth R Wagner; H James; Per-Olof Hasselgren; Josef E Fischer
Tissue metabolite levels in different types of skeletal muscle during sepsis.
Metabolism: clinical and experimental 1991;40(11):1147-51.
1990: Kenneth R Wagner; M Kleinholz; R E Myers
Delayed decreases in specific brain mitochondrial electron transfer complex activities and cytochrome concentrations following anoxia/ischemia.
Journal of the neurological sciences 1990;100(1-2):142-51.
1990: Kenneth R Wagner; M Kleinholz; R E Myers
Delayed onset of neurologic deterioration following anoxia/ischemia coincides with appearance of impaired brain mitochondrial respiration and decreased cytochrome oxidase activity.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(3):417-23.
1990: Gabrielle M De Courten-Myers; R E Myers; Kenneth R Wagner
Effect of hyperglycemia on infarct size after cerebrovascular occlusion in cats.
Stroke; a journal of cerebral circulation 1990;21(2):357-8.
1990: Gabrielle M De Courten-Myers; M Kleinholz; Kenneth R Wagner; R E Myers
Determiners of fatal reperfusion brain oedema.
Acta neurochirurgica. Supplementum 1990;51():226-9.
1989: Gabrielle M De Courten-Myers; M Kleinholz; Kenneth R Wagner; R E Myers
Fatal strokes in hyperglycemic cats.
Stroke; a journal of cerebral circulation 1989;20(12):1707-15.
1989: Kenneth R Wagner; M Kleinholz; R E Myers
Delayed neurologic deterioration following anoxia: brain mitochondrial and metabolic correlates.
Journal of neurochemistry 1989;52(5):1407-17.
1987: R E Myers; Gabrielle M De Courten-Myers; Kenneth R Wagner
Blood glucose levels after cardiac arrest.
Neurology 1987;37(7):1267-8.
1986: Kenneth R Wagner; R E Myers
Hyperglycemia preserves brain mitochondrial respiration during anoxia.
Journal of neurochemistry 1986;47(5):1620-6.
1986: Kenneth R Wagner; P Ting; Margaret V Westfall; S Yamaguchi; J D Bacher; R E Myers
Brain metabolic correlates of hypoxic-ischemic cerebral necrosis in mid-gestational sheep fetuses: significance of hypotension.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1986;6(4):425-34.
1985: Gabrielle M De Courten-Myers; S Yamaguchi; Kenneth R Wagner; P Ting; R E Myers
Brain injury from marked hypoxia in cats: role of hypotension and hyperglycemia.
Stroke; a journal of cerebral circulation 1985;16(6):1016-21.
1985: Kenneth R Wagner; R E Myers
Topography of brain metabolites: rhesus monkey, goat, and cat.
Experimental neurology 1985;89(1):146-58.