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Claes Wahlestedt

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Olof Gidlöf; Patrik Gilje; Jenny Ohman; Björn Olde; Marcel van der Brug; Claes Wahlestedt; David Erlinge
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression.
Veronica J Peschansky; Zicai Liang; Claes Wahlestedt
RNAi joins the "Singles Club".
Marco Magistri; Georges St Laurent; Mohammad Faghihi; Claes Wahlestedt
Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts.

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All Publications

2013: Olof Gidlöf; Patrik Gilje; Jenny Ohman; Björn Olde; Marcel van der Brug; Claes Wahlestedt; David Erlinge
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression.
Blood 2013;121(19):3908-17.
2012: Veronica J Peschansky; Zicai Liang; Claes Wahlestedt
RNAi joins the "Singles Club".
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(11):2010-1.
2012: Marco Magistri; Georges St Laurent; Mohammad Faghihi; Claes Wahlestedt
Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts.
Trends in genetics : TIG 2012;28(8):389-96.
2012: Gopi Kumar Mittapalli; Shaun P. Brothers; Marion Toussaint; Danielle Vellucci; Claes Wahlestedt; Jun Yang; Edward Roberts
Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists.
Bioorganic & medicinal chemistry letters 2012;22(12):3916-20.
2012: Chiara Pastori; Claes Wahlestedt
Involvement of long noncoding RNAs in diseases affecting the central nervous system.
RNA biology 2012;9(6):860-70.
2012: Farzaneh Modarresi; Marcel P van der Brug; Shaun P. Brothers; Mohammad Faghihi; Roya Pedram Fatemi; Miguel A Lopez-Toledano; Marco Magistri; Claes Wahlestedt
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation.
Nature biotechnology 2012;30(5):453-9.
2012: Brooke H Miller; Robert H Roth; Julia Strathmann; Shibing Deng; Dieter Edbauer; John D Elsworth; Paul J Kenny; Robin J Kleiman; Thomas A Lanz; Matthew S Lawrence; David Willoughby; Li Xi; Zane Zeier; Claes Wahlestedt
MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(8):3125-30.
2012: Georges St Laurent; Michael R Tackett; Silvio Urcuqui-Inchima; Claes Wahlestedt; Zhaoqing Yang; Tatyana Eremina; Timothy A McCaffrey; Bernd Seilheimer; Dmitry Shtokalo; Philipp Kapranov
Intronic RNAs constitute the major fraction of the non-coding RNA in mammalian cells.
BMC genomics 2012;13():504.
2012: Gregory C Sartor; Georges St Laurent; Claes Wahlestedt
The Emerging Role of Non-Coding RNAs in Drug Addiction.
Frontiers in genetics 2012;3():106.
2011: Michael B Clark; Marcel Dinger; Mark B Gerstein; Thomas R Gingeras; Yoshihide Hayashizaki; Paulo P Amaral; piero carninci; Antonin Morillon; Kevin V Morris; Chris P Ponting; John L Rinn; Joel S Rozowsky; Felix J Schlesinger; Peter F Stadler; Ryan J Taft; Claes Wahlestedt; John S Mattick
The reality of pervasive transcription.
PLoS biology 2011;9(7):e1000625; discussion e1001102.
2011: Farzaneh Modarresi; Nikunj S Patel; Barbara G Sahagan; Claes Wahlestedt; Mohammad Ali Faghihi; Miguel A Lopez-Toledano
Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis.
International journal of Alzheimer's disease 2011;2011():929042.
2010: Shaun P. Brothers; Claes Wahlestedt
Therapeutic potential of neuropeptide Y (NPY) receptor ligands.
EMBO molecular medicine 2010;2(11):429-39.
2010: Jose P Silva; Claes Wahlestedt
Role of Sirtuin 1 in metabolic regulation.
Drug discovery today 2010;15(17-18):781-91.
2010: Jonathan A Hollander; Heh-In Im; Antonio L Amelio; Jannet Kocerha; Purva Bali; Qun Lu; David Willoughby; Claes Wahlestedt; Michael D Conkright; Paul J Kenny
Striatal microRNA controls cocaine intake through CREB signalling.
Nature 2010;466(7303):197-202.
2010: Kai-Christian Sonntag; Claes Wahlestedt
RNA mechanisms in CNS systems and disorders.
Brain research 2010;1338():1-2.
2010: Brooke H Miller; Claes Wahlestedt
MicroRNA dysregulation in psychiatric disease.
Brain research 2010;1338():89-99.
2010: James A Timmons; Steen Knudsen; Tuomo Rankinen; Lauren G Koch; Mark A Sarzynski; Thomas Jensen; Pernille Keller; Camilla Scheele; Niels B J Vollaard; Søren Nielsen; Thorbjörn Akerström; Ormond A MacDougald; Eva Jansson; Paul L Greenhaff; Mark A Tarnopolsky; Luc J C van Loon; Bente K Pedersen; Carl Johan Sundberg; Claes Wahlestedt; steven britton; Claude Bouchard
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans.
Journal of applied physiology (Bethesda, Md. : 1985) 2010;108(6):1487-96.
2010: Marcel P van der Brug; Claes Wahlestedt
Navigating genomic maps of cancer cells.
Nature biotechnology 2010;28(3):241-2.
2010: Mohammad Faghihi; Jannet Kocerha; Farzaneh Modarresi; Pär G Engström; Alistair Chalk; Shaun P. Brothers; Eric Koesema; Georges St Laurent; Claes Wahlestedt
RNAi screen indicates widespread biological function for human natural antisense transcripts.
PloS one 2010;5(10):.
2010: Mohammad Faghihi; Ming Zhang; Jia Huang; Farzaneh Modarresi; Marcel P Van der Brug; Michael A Nalls; Mark Cookson; Georges St-Laurent; Claes Wahlestedt
Evidence for natural antisense transcript-mediated inhibition of microRNA function.
Genome biology 2010;11(5):R56.
2010: Iain J Gallagher; Camilla Scheele; Pernille Keller; Anders R Nielsen; Judit Remenyi; Christian P Fischer; Karim Roder; John Babraj; Claes Wahlestedt; Gyorgy Hutvagner; Bente K Pedersen; James A Timmons
Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes.
Genome medicine 2010;2(2):9.
2010: Miguel Angel Lopez-Toledano; Mohammad Ali Faghihi; Nikunj S Patel; Claes Wahlestedt
Adult neurogenesis: a potential tool for early diagnosis in Alzheimer's disease?
Journal of Alzheimer's disease : JAD 2010;20(2):395-408.
2010: Shaun P. Brothers; S Adrian Saldanha; Timothy P Spicer; Michael Cameron; Becky A Mercer; Peter Chase; Patricia McDonald; Claes Wahlestedt; Peter S Hodder
Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening.
Molecular pharmacology 2010;77(1):46-57.
2009: Georges St Laurent; Mohammad Faghihi; Claes Wahlestedt
Non-coding RNA transcripts: sensors of neuronal stress, modulators of synaptic plasticity, and agents of change in the onset of Alzheimer's disease.
Neuroscience letters 2009;466(2):81-8.
2009: Mohammad Faghihi; Claes Wahlestedt
Regulatory roles of natural antisense transcripts.
Nature reviews. Molecular cell biology 2009;10(9):637-43.
2009: Christian Schönbach; Alistair Forrest; Erik van Nimwegen; Carsten O Daub; Piotr J Balwierz; Katharine M Irvine; Timo Lassmann; Timothy Ravasi; Yuki Hasegawa; Michiel J L de Hoon; Shintaro Katayama; Kate Schroder; piero carninci; Yasuhiro Tomaru; Mutsumi Kanamori-Katayama; Atsutaka Kubosaki; Altuna Akalin; Yoshinari Ando; Erik Arner; Maki Asada; Hiroshi Asahara; Timothy Bailey; Vladimir Bajic; Denis Bauer; Anthony Beckhouse; Nicolas Bertin; Johan Björkegren; Frank Brombacher; Erika Bulger; Alistair Chalk; Joe Chiba; Nicole Cloonan; Adam Dawe; Josee Dostie; Pär G Engström; Magbubah Essack; Geoffrey J Faulkner; J Lynn Fink; David Fredman; Ko Fujimori; Masaaki Furuno; Takashi Gojobori; Julian Gough; Sean M Grimmond; Mika Gustafsson; Megumi Hashimoto; Takehiro Hashimoto; Mariko Hatakeyama; Susanne Heinzel; Winston Hide; Oliver Hofmann; Michael Hörnquist; Lukasz Huminiecki; Kazuho Ikeo; Naoko Imamoto; Satoshi Inoue; Yusuke Inoue; Ryoko Ishihara; Takao Iwayanagi; Anders Jacobsen; Mandeep Kaur; Hideya Kawaji; Markus C Kerr; Ryuichiro Kimura; Syuhei Kimura; Yasumasa Kimura; Hiroaki Kitano; Hisashi Koga; Toshio Kojima; Shinji Kondo; Takeshi Konno; Anders Krogh; Adele Kruger; Ajit Kumar; Boris Lenhard; Andreas Lennartsson; Morten Lindow; Marina Lizio; Cameron Macpherson; Norihiro Maeda; Christopher A. Maher; Monique Maqungo; Jessica Mar; Nicholas A Matigian; Hideo Matsuda; John S Mattick; Stuart Meier; Sei Miyamoto; Etsuko Miyamoto-Sato; Kazuhiko Nakabayashi; Yutaka Nakachi; Mika Nakano; Sanne Nygaard; Toshitsugu Okayama; Yasushi Okazaki; Haruka Okuda-Yabukami; Valerio Orlando; Jun Otomo; Mikhail Pachkov; Nikolai Petrovsky; Charles Plessy; John Quackenbush; Aleksandar Radovanovic; Michael Rehli; Rintaro Saito; Albin Sandelin; Sebastian Schmeier; Christian Schönbach; Ariel S Schwartz; Colin A Semple; Miho Sera; Jessica Severin; Katsuhiko Shirahige; Cas Simons; George St Laurent; Masanori Suzuki; Takahiro Suzuki; Matthew J Sweet; Ryan J Taft; Shizu Takeda; Yoichi Takenaka; Kai Tan; Martin S Taylor; Rohan D Teasdale; Jesper Tegnér; Sarah Teichmann; Eivind Valen; Claes Wahlestedt; Kazunori Waki; Andrew Waterhouse; Christine A Wells; Ole Winther; Linda Wu; Kazumi Yamaguchi; Hiroshi Yanagawa; Jun Yasuda; Mihaela Zavolan; David A Hume; Takahiro Arakawa; Shiro Fukuda; Kengo Imamura; Chikatoshi Kai; Ai Kaiho; Tsugumi Kawashima; Chika Kawazu; Yayoi Kitazume; Miki Kojima; Hisashi Miura; Kayoko Murakami; Mitsuyoshi Murata; Noriko Ninomiya; Hiromi Nishiyori; Shohei Noma; Chihiro Ogawa; Takuma Sano; Christophe Simon; Michihira Tagami; Yukari Takahashi; Jun Kawai; Yoshihide Hayashizaki
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.
Nature genetics 2009;41(5):553-62.
2009: Jannet Kocerha; Mohammad Faghihi; Miguel Angel Lopez-Toledano; Jia Huang; Amy J Ramsey; Marc G Caron; Nicole Sales; David Willoughby; Joacim Elmen; Henrik F Hansen; Henrik Orum; Sakari Kauppinen; Paul J Kenny; Claes Wahlestedt
MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3507-12.
2009: Jannet Kocerha; Sakari Kauppinen; Claes Wahlestedt
microRNAs in CNS disorders.
Neuromolecular medicine 2009;11(3):162-72.
2008: P W Franks; C Scheele; R J F Loos; A R Nielsen; F M Finucane; Claes Wahlestedt; B K Pedersen; N J Wareham; J A Timmons
Genomic variants at the PINK1 locus are associated with transcript abundance and plasma nonesterified fatty acid concentrations in European whites.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(9):3135-45.
2008: Ge Shan; Yujing Li; Junliang Zhang; Wendi Li; Keith E Szulwach; Ranhui Duan; Mohammad Faghihi; Ahmad M Khalil; Lianghua Lu; Zain Paroo; Anthony W S Chan; Zhangjie Shi; Qinghua Liu; Claes Wahlestedt; Chuan He; Peng Jin
A small molecule enhances RNA interference and promotes microRNA processing.
Nature biotechnology 2008;26(8):933-40.
2008: Mohammad Faghihi; Farzaneh Modarresi; Ahmad M Khalil; Douglas E Wood; Barbara G Sahagan; Todd E Morgan; Caleb E Finch; Georges St Laurent; Paul J Kenny; Claes Wahlestedt
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase.
Nature medicine 2008;14(7):723-30.
2008: Cecilia Dahlgren; Hong-Yan Zhang; Quan Du; Maria Grahn; Gunnar Norstedt; Claes Wahlestedt; Zicai Liang
Analysis of siRNA specificity on targets with double-nucleotide mismatches.
Nucleic acids research 2008;36(9):e53.
2008: Junmei Hong; Na Wei; Alistair Chalk; Jue Wang; Yutong Song; Fan Yi; Ren-Ping Qiao; Erik L L Sonnhammer; Claes Wahlestedt; Zicai Liang; Quan Du
Focusing on RISC assembly in mammalian cells.
Biochemical and biophysical research communications 2008;368(3):703-8.
2008: Jia Huang; Brandon Young; Mathew Pletcher; Markus Heilig; Claes Wahlestedt
Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence.
Addiction biology 2008;13(1):88-94.
2008: Ahmad M Khalil; Claes Wahlestedt
Epigenetic mechanisms of gene regulation during mammalian spermatogenesis.
Epigenetics : official journal of the DNA Methylation Society 2008;3(1):21-8.
2008: Ahmad M Khalil; Mohammad Faghihi; Farzaneh Modarresi; Shaun P. Brothers; Claes Wahlestedt
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome.
PloS one 2008;3(1):e1486.
2008: Danielle Kemmer; Raf M Podowski; Dimas Yusuf; Jochen Brumm; Warren Cheung; Claes Wahlestedt; Boris Lenhard; Wyeth W Wasserman
Gene characterization index: assessing the depth of gene annotation.
PloS one 2008;3(1):e1440.
2007: Georges St Laurent; Claes Wahlestedt
Noncoding RNAs: couplers of analog and digital information in nervous system function?
Trends in neurosciences 2007;30(12):612-21.
2007: Camilla Scheele; Anders Rinnov Nielsen; Tomas B Walden; Dean A Sewell; Christian Fischer; Robert J Brogan; Natasa Petrovic; Ola Larsson; Per A Tesch; Kristian Wennmalm; Dana S Hutchinson; Barbara Cannon; Claes Wahlestedt; Bente Klarlund Pedersen; James A Timmons
Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(13):3653-65.
2007: James A Timmons; Kristian Wennmalm; Ola Larsson; Tomas B Walden; Timo Lassmann; Natasa Petrovic; David Hamilton; Ruth E Gimeno; Claes Wahlestedt; Keith Baar; Jan Nedergaard; Barbara Cannon
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4401-6.
2007: Camilla Scheele; Natasa Petrovic; Mohammad Faghihi; Timo Lassmann; Katarina Fredriksson; Olav Rooyackers; Claes Wahlestedt; Liam Good; James A Timmons
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function.
BMC genomics 2007;8():74.
2006: Claes Wahlestedt
Natural antisense and noncoding RNA transcripts as potential drug targets.
Drug discovery today 2006;11(11-12):503-8.
2006: piero carninci; Albin Sandelin; Boris Lenhard; Shintaro Katayama; Kazuro Shimokawa; Jasmina Ponjavic; Colin Semple; Martin Taylor; Pär G Engström; Martin C Frith; Alistair Forrest; Wynand B Alkema; Sin Lam Tan; Charles Plessy; Rimantas Kodzius; Timothy Ravasi; Takeya Kasukawa; Shiro Fukuda; Mutsumi Kanamori-Katayama; Yayoi Kitazume; Hideya Kawaji; Chikatoshi Kai; Mari Nakamura; Hideaki Konno; Kenji Nakano; Salim Mottagui-Tabar; Peter Arner; Alessandra Chesi; Stefano Gustincich; Francesca Persichetti; Harukazu Suzuki; Sean M Grimmond; Christine A Wells; Valerio Orlando; Claes Wahlestedt; Edison Liu; Matthias Harbers; Jun Kawai; Vladimir Bajic; David A Hume; Yoshihide Hayashizaki
Genome-wide analysis of mammalian promoter architecture and evolution.
Nature genetics 2006;38(6):626-35.
2006: Pär G Engström; Harukazu Suzuki; Noriko Ninomiya; Altuna Akalin; Luca Sessa; Giovanni Lavorgna; Alessandro Brozzi; Lucilla Luzi; Sin Lam Tan; Liang Yang; Galih Kunarso; Edwin Lian-Chong Ng; Serge Batalov; Claes Wahlestedt; Chikatoshi Kai; Jun Kawai; piero carninci; Yoshihide Hayashizaki; Christine Wells; Vladimir Bajic; Valerio Orlando; James F Reid; Boris Lenhard; Leonard Lipovich
Complex Loci in human and mouse genomes.
PLoS genetics 2006;2(4):e47.
2006: Martin C Frith; Laurens G Wilming; Alistair Forrest; Hideya Kawaji; Sin Lam Tan; Claes Wahlestedt; Vladimir Bajic; Chikatoshi Kai; Jun Kawai; piero carninci; Yoshihide Hayashizaki; Timothy Lawrence Bailey; Lukasz Huminiecki
Pseudo-messenger RNA: phantoms of the transcriptome.
PLoS genetics 2006;2(4):e23.
2006: Cecilia Dahlgren; Claes Wahlestedt; Håkan Thonberg
No induction of anti-viral responses in human cell lines HeLa and MCF-7 when transfecting with siRNA or siLNA.
Biochemical and biophysical research communications 2006;341(4):1211-7.
2006: David Fredman; Sarah L Sawyer; Linda Strömqvist; Salim Mottagui-Tabar; Kenneth K Kidd; Claes Wahlestedt; STEPHEN CHANOCK; Anthony J Brookes
Nonsynonymous SNPs: validation characteristics, derived allele frequency patterns, and suggestive evidence for natural selection.
Human mutation 2006;27(2):173-86.
2006: Ola Larsson; David M Perlman; Danhua Fan; Cavan S Reilly; Mark Peterson; Cecilia Dahlgren; Zicai Liang; Shunan Li; Vitaly A Polunovsky; Claes Wahlestedt; Peter B Bitterman
Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure.
Nucleic acids research 2006;34(16):4375-86.
2006: Hong-Yan Zhang; Quan Du; Claes Wahlestedt; Zicai Liang
RNA Interference with chemically modified siRNA.
Current topics in medicinal chemistry 2006;6(9):893-900.
2006: Mohammad Faghihi; Claes Wahlestedt
RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals.
Genome biology 2006;7(5):R38.
2006: James A Timmons; Jessica Norrbom; Camilla Schéele; Håkan Thonberg; Claes Wahlestedt; Per A Tesch
Expression profiling following local muscle inactivity in humans provides new perspective on diabetes-related genes.
Genomics 2006;87(1):165-72.
2005: Shane McCarthy; Salim Mottagui-Tabar; Yumi Mizuno; Bengt Sennblad; Johan Hoffstedt; Peter Arner; Claes Wahlestedt; Björn Andersson
Complex HTR2C linkage disequilibrium and promoter associations with body mass index and serum leptin.
Human genetics 2005;117(6):545-57.
2005: S Katayama; Y Tomaru; T Kasukawa; Kazunori Waki; M Nakanishi; M Nakamura; H Nishida; C C Yap; M Suzuki; J Kawai; H Suzuki; piero carninci; Y Hayashizaki; C Wells; M Frith; T Ravasi; K C Pang; J Hallinan; J Mattick; D A Hume; Leonard Lipovich; S Batalov; P G Engström; Y Mizuno; Mohammad Faghihi; A Sandelin; Alistair Chalk; S Mottagui-Tabar; Z Liang; B Lenhard; Claes Wahlestedt
Antisense transcription in the mammalian transcriptome.
Science (New York, N.Y.) 2005;309(5740):1564-6.
2005: piero carninci; T Kasukawa; S Katayama; J Gough; M C Frith; N Maeda; R Oyama; T Ravasi; B Lenhard; C Wells; R Kodzius; K Shimokawa; Vladimir Bajic; S E Brenner; S Batalov; Alistair Forrest; M Zavolan; M J Davis; L G Wilming; V Aidinis; J E Allen; A Ambesi-Impiombato; R Apweiler; R N Aturaliya; Timothy Lawrence Bailey; M Bansal; L Baxter; K W Beisel; Tom Bersano; H Bono; Alistair Chalk; K P Chiu; V Choudhary; A Christoffels; D R Clutterbuck; M L Crowe; E Dalla; B P Dalrymple; B de Bono; G Della Gatta; D di Bernardo; T Down; P Engstrom; M Fagiolini; G Faulkner; C F Fletcher; T Fukushima; M Furuno; S Futaki; manuela gariboldi; P Georgii-Hemming; Thomas Gingeras; Takashi Gojobori; R E Green; S Gustincich; M Harbers; Y Hayashi; T K Hensch; N Hirokawa; D Hill; L Huminiecki; M Iacono; Kazuho Ikeo; A Iwama; T Ishikawa; M Jakt; Alexander Kanapin; M Katoh; Y Kawasawa; J Kelso; H Kitamura; H Kitano; george kollias; S P T Krishnan; A Kruger; S K Kummerfeld; I V Kurochkin; L F Lareau; D Lazarevic; Leonard Lipovich; J Liu; S Liuni; S McWilliam; M Madan Babu; M Madera; LUIGI MARCHIONNI; H Matsuda; S Matsuzawa; H Miki; F Mignone; S Miyake; K Morris; S Mottagui-Tabar; N Mulder; N Nakano; H Nakauchi; P Ng; R Nilsson; S Nishiguchi; S Nishikawa; F Nori; O Ohara; Yasushi Okazaki; V Orlando; K C Pang; W J Pavan; G Pavesi; G Pesole; Nikolai Petrovsky; S Piazza; J Reed; J F Reid; B Z Ring; M Ringwald; B Rost; Y Ruan; Steven L Salzberg; A Sandelin; C Schneider; Christian Schönbach; K Sekiguchi; Colin Semple; S Seno; L Sessa; Y Sheng; Y Shibata; H Shimada; K Shimada; D Silva; B Sinclair; S Sperling; Elia Stupka; K Sugiura; R Sultana; Y Takenaka; K Taki; K Tammoja; S L Tan; S Tang; Martin Taylor; J Tegner; S A Teichmann; H R Ueda; E van Nimwegen; R Verardo; C L Wei; K Yagi; H Yamanishi; E Zabarovsky; S Zhu; A Zimmer; Winston Hide; Carol Bult; S M Grimmond; Rohan Teasdale; Edison Liu; V Brusic; John Quackenbush; Claes Wahlestedt; J S Mattick; D A Hume; C Kai; D Sasaki; Y Tomaru; S Fukuda; M Kanamori-Katayama; M Suzuki; J Aoki; T Arakawa; J Iida; K Imamura; Masayoshi Itoh; T Kato; Hideya Kawaji; N Kawagashira; T Kawashima; M Kojima; S Kondo; H Konno; K Nakano; N Ninomiya; T Nishio; M Okada; C Plessy; K Shibata; T Shiraki; S Suzuki; M Tagami; Kazunori Waki; A Watahiki; Y Okamura-Oho; H Suzuki; J Kawai; Y Hayashizaki
The transcriptional landscape of the mammalian genome.
Science (New York, N.Y.) 2005;309(5740):1559-63.
2005: Salim Mottagui-Tabar; Jonathan A Prince; Claes Wahlestedt; Guanshan Zhu; David Goldman; Markus Heilig
A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence.
Alcoholism, clinical and experimental research 2005;29(5):702-7.
2005: James A Timmons; Ola Larsson; Eva Jansson; Helene Fischer; Gustafsson Thomas; Paul L Greenhaff; John Ridden; Jonathan Rachman; Myriam Peyrard-Janvid; Claes Wahlestedt; Carl Johan Sundberg
Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):750-60.
2005: Bo Ding; Björn Kull; Zhurong Liu; Salim Mottagui-Tabar; Håkan Thonberg; Harvest F Gu; Anthony J Brookes; Lars Grundemar; Christina Karlsson; Anders Hamsten; Peter Arner; Claes-Göran Ostenson; Suad Efendic; Magnus Monné; Gunnar von Heijne; Per Eriksson; Claes Wahlestedt
Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function.
Regulatory peptides 2005;127(1-3):45-53.
2005: Meihong Chen; Lishu Zhang; Hong-Yan Zhang; Xiahui Xiong; Bo Wang; Quan Du; Bing Lu; Claes Wahlestedt; Zicai Liang
A universal plasmid library encoding all permutations of small interfering RNA.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(7):2356-61.
2005: Meihong Chen; Quan Du; Hong-Yan Zhang; Claes Wahlestedt; Zicai Liang
Vector-based siRNA delivery strategies for high-throughput screening of novel target genes.
Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research 2005;1(1):5-11.
2005: Kristian Wennmalm; Claes Wahlestedt; Ola Larsson
The expression signature of in vitro senescence resembles mouse but not human aging.
Genome biology 2005;6(13):R109.
2005: Ola Larsson; Claes Wahlestedt; James A Timmons
Considerations when using the significance analysis of microarrays (SAM) algorithm.
BMC bioinformatics 2005;6():129.
2005: Quan Du; Håkan Thonberg; Jue Wang; Claes Wahlestedt; Zicai Liang
A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites.
Nucleic acids research 2005;33(5):1671-7.
2005: Salim Mottagui-Tabar; Mohammad Faghihi; Yosuke Mizuno; Pär G Engström; Boris Lenhard; Wyeth W Wasserman; Claes Wahlestedt
Identification of functional SNPs in the 5-prime flanking sequences of human genes.
BMC genomics 2005;6():18.
2005: Joacim Elmén; Håkan Thonberg; Karl Ljungberg; Miriam Frieden; Majken Westergaard; Yunhe Xu; Britta Wahren; Zicai Liang; Henrik Ørum; Troels Koch; Claes Wahlestedt
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality.
Nucleic acids research 2005;33(1):439-47.
2005: Ken C Pang; Stuart Stephen; Pär G Engström; Khairina Tajul-Arifin; Weisan Chen; Claes Wahlestedt; Boris Lenhard; Yoshihide Hayashizaki; John S Mattick
RNAdb--a comprehensive mammalian noncoding RNA database.
Nucleic acids research 2005;33(Database issue):D125-30.
2004: Joacim Elmén; Hong-Yan Zhang; Bartek Zuber; Karl Ljungberg; Britta Wahren; Claes Wahlestedt; Zicai Liang
Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication.
FEBS letters 2004;578(3):285-90.
2004: Claes Wahlestedt; Anthony J Brookes; Salim Mottagui-Tabar
Lower rate of genomic variation identified in the trans-membrane domain of monoamine sub-class of Human G-Protein Coupled Receptors: the Human GPCR-DB Database.
BMC genomics 2004;5():91.
2004: Quan Du; Håkan Thonberg; Hong-Yan Zhang; Claes Wahlestedt; Zicai Liang
Validating siRNA using a reporter made from synthetic DNA oligonucleotides.
Biochemical and biophysical research communications 2004;325(1):243-9.
2004: Salim Mottagui-Tabar; Shane McCarthy; Jana Reinemund; Björn Andersson; Claes Wahlestedt; Markus Heilig
Analysis of 5-hydroxytryptamine 2c receptor gene promoter variants as alcohol-dependence risk factors.
Alcohol and alcoholism (Oxford, Oxfordshire) 2004;39(5):380-5.
2004: Alistair Chalk; Claes Wahlestedt; Erik L L Sonnhammer
Improved and automated prediction of effective siRNA.
Biochemical and biophysical research communications 2004;319(1):264-74.
2004: Håkan Thonberg; Camilla Schéele; Cecilia Dahlgren; Claes Wahlestedt
Characterization of RNA interference in rat PC12 cells: requirement of GERp95.
Biochemical and biophysical research communications 2004;318(4):927-34.
2004: Mohammad Faghihi; Salim Mottagui-Tabar; Claes Wahlestedt
Genetics of neurological disorders.
Expert review of molecular diagnostics 2004;4(3):317-32.
2004: Yunhe Xu; Annika Linde; Ola Larsson; Dorit Thormeyer; Joacim Elmen; Claes Wahlestedt; Zicai Liang
Functional comparison of single- and double-stranded siRNAs in mammalian cells.
Biochemical and biophysical research communications 2004;316(3):680-7.
2004: Markus Heilig; Olof Zachrisson; Annika Thorsell; Anna Ehnvall; Salim Mottagui-Tabar; Magnus Sjögren; Marie Asberg; Rolf Ekman; Claes Wahlestedt; Hans Agren
Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism.
Journal of psychiatric research 2004;38(2):113-21.
2004: Harvest F Gu; Adili Abulaiti; Claes-Göran Ostenson; Keith Humphreys; Claes Wahlestedt; Anthony J Brookes; Suad Efendic
Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians.
Diabetes 2004;53 Suppl 1():S31-5.
2004: Ola Larsson; Camilla Scheele; Zicai Liang; Jurgen Moll; Christina Karlsson; Claes Wahlestedt
Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model.
Cancer research 2004;64(2):482-9.
2004: Danielle Kemmer; Margareta Faxén; Emily Hodges; Jonathan Lim; Elena Herzog; Elsebrit Ljungström; Anders Lundmark; Mary K Olsen; Raf Podowski; Erik L L Sonnhammer; Peter Nilsson; Mark Reimers; Boris Lenhard; Steven L Roberds; Claes Wahlestedt; Christer Höög; Pankaj Agarwal; Wyeth W Wasserman
Exploring the foundation of genomics: a northern blot reference set for the comparative analysis of transcript profiling technologies.
Comparative and functional genomics 2004;5(8):584-95.
2004: Håkan Thonberg; Cecilia Dahlgren; Claes Wahlestedt
Antisense-induced Fas mRNA degradation produces site-specific stable 3'-mRNA fragment by exonuclease cleavage at the complementary sequence.
Oligonucleotides 2004;14(3):221-6.
2004: Ruben Isacson; Björn Kull; Claes Wahlestedt; Peter Salmi
A 68930 and dihydrexidine inhibit locomotor activity and d-amphetamine-induced hyperactivity in rats: a role of inhibitory dopamine D(1/5) receptors in the prefrontal cortex?
Neuroscience 2004;124(1):33-42.
2003: Ruben Isacson; Björn Kull; Peter Salmi; Claes Wahlestedt
Lack of efficacy of 'naked' small interfering RNA applied directly to rat brain.
Acta physiologica Scandinavica 2003;179(2):173-7.
2003: Hong-Yan Zhang; Jianping Mao; Daixing Zhou; Yunhe Xu; Håkan Thonberg; Zicai Liang; Claes Wahlestedt
mRNA accessible site tagging (MAST): a novel high throughput method for selecting effective antisense oligonucleotides.
Nucleic acids research 2003;31(14):e72.
2003: Johanna Kela; Peter Salmi; Roberto Rimondini-Giorgini; Markus Heilig; Claes Wahlestedt
Behavioural analysis of melanin-concentrating hormone in rats: evidence for orexigenic and anxiolytic properties.
Regulatory peptides 2003;114(2-3):109-14.
2003: Yunhe Xu; Hong-Yan Zhang; Dorit Thormeyer; Ola Larsson; Quan Du; Joacim Elmén; Claes Wahlestedt; Zicai Liang
Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs.
Biochemical and biophysical research communications 2003;306(3):712-7.
2003: Boris Lenhard; Claes Wahlestedt; Wyeth W Wasserman
GeneLynx mouse: integrated portal to the mouse genome.
Genome research 2003;13(6B):1501-4.
2003: Jenny Ahlqvist; Ruben Isacson; Claes Wahlestedt; Peter Salmi
Anti-cataleptic effects of clozapine, but not olanzapine and quetiapine, on SCH 23390- or raclopride-induced catalepsy in rats.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(3):177-82.
2003: Anna Eriksson; Renhai Cao; Joy Roy; Katerina Tritsaris; Claes Wahlestedt; Steen Dissing; Johan Thyberg; Yihai Cao
Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability.
Circulation 2003;107(11):1532-8.
2003: Anna Josephson; Alexandra Trifunovski; Camilla Schéele; Johan Widenfalk; Claes Wahlestedt; Stefan Brené; Lars Olson; Christian Spenger
Activity-induced and developmental downregulation of the Nogo receptor.
Cell and tissue research 2003;311(3):333-42.
2003: Dorit Thormeyer; Ole Ammerpohl; Ola Larsson; Y Xu; A Asinger; Claes Wahlestedt; Z Liang
Characterization of lacZ complementation deletions using membrane receptor dimerization.
BioTechniques 2003;34(2):346-50, 352-5.
2003: Claes Wahlestedt
Array of possibilities.
Pharmacogenetics 2003;13(1):1.
2003: Guanshan Zhu; Lotta Pollak; Salim Mottagui-Tabar; Claes Wahlestedt; Julie Taubman; Matti Virkkunen; David Goldman; Markus Heilig
NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations.
Alcoholism, clinical and experimental research 2003;27(1):19-24.
2003: Peter Salmi; Johanna Kela; Ulf Arvidsson; Claes Wahlestedt
Functional interactions between delta- and mu-opioid receptors in rat thermoregulation.
European journal of pharmacology 2003;458(1-2):101-6.
2002: Yasushi Okazaki; M Furuno; T Kasukawa; J Adachi; H Bono; S Kondo; I Nikaido; N Osato; R Saito; H Suzuki; I Yamanaka; H Kiyosawa; K Yagi; Y Tomaru; Y Hasegawa; A Nogami; Christian Schönbach; Takashi Gojobori; R Baldarelli; D P Hill; Carol Bult; D A Hume; John Quackenbush; Lynn M Schriml; Alexander Kanapin; H Matsuda; S Batalov; K W Beisel; J A Blake; D Bradt; V Brusic; C Chothia; L E Corbani; S Cousins; E Dalla; T A Dragani; C F Fletcher; Alistair Forrest; K S Frazer; T Gaasterland; manuela gariboldi; C Gissi; A Godzik; J Gough; S Grimmond; S Gustincich; N Hirokawa; I J Jackson; E D Jarvis; A Kanai; Hideya Kawaji; Y Kawasawa; R M Kedzierski; B L King; A Konagaya; I V Kurochkin; Y Lee; B Lenhard; P A Lyons; D R Maglott; L Maltais; LUIGI MARCHIONNI; L McKenzie; H Miki; T Nagashima; K Numata; T Okido; W J Pavan; G Pertea; G Pesole; Nikolai Petrovsky; R Pillai; J U Pontius; D Qi; S Ramachandran; T Ravasi; J C Reed; D J Reed; J Reid; B Z Ring; M Ringwald; A Sandelin; C Schneider; Colin Semple; M Setou; K Shimada; R Sultana; Y Takenaka; Martin Taylor; Rohan Teasdale; M Tomita; R Verardo; L Wagner; Claes Wahlestedt; Y Wang; Y Watanabe; C Wells; L G Wilming; A Wynshaw-Boris; M Yanagisawa; I Yang; L Yang; Z Yuan; M Zavolan; Y Zhu; A Zimmer; piero carninci; N Hayatsu; T Hirozane-Kishikawa; H Konno; M Nakamura; N Sakazume; K Sato; T Shiraki; Kazunori Waki; J Kawai; K Aizawa; T Arakawa; S Fukuda; A Hara; W Hashizume; K Imotani; Y Ishii; Masayoshi Itoh; I Kagawa; A Miyazaki; K Sakai; D Sasaki; K Shibata; A Shinagawa; A Yasunishi; M Yoshino; R Waterston; E S Lander; J Rogers; E Birney; Y Hayashizaki
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Nature 2002;420(6915):563-73.
2002: Ola Larsson; Dorit Thormeyer; Arian Asinger; Björn Wihlén; Claes Wahlestedt; Zicai Liang
Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptides.
Nucleic acids research 2002;30(23):e133.
2002: Jingfeng Li; Alexei Protopopov; Fuli Wang; Vera Senchenko; Valentin Petushkov; Olga Vorontsova; Lev Petrenko; Veronika I Zabarovska; Olga V Muravenko; Eleonora Braga; Lev L Kisselev; Michael I Lerman; Vladimir I Kashuba; George Klein; Ingemar Ernberg; Claes Wahlestedt; Eugene R Zabarovsky
NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10724-9.
2002: Alexey S Kutsenko; Rinat Z Gizatullin; Ali N Al-Amin; Fuli Wang; Sergei M Kvasha; Raf M Podowski; Yuri G Matushkin; Anita Gyanchandani; Olga V Muravenko; Viktor G Levitsky; Nikolay A Kolchanov; Alexei Protopopov; Vladimir I Kashuba; Lev L Kisselev; Wyeth W Wasserman; Claes Wahlestedt; Eugene R Zabarovsky
NotI flanking sequences: a tool for gene discovery and verification of the human genome.
Nucleic acids research 2002;30(14):3163-70.
2002: B Ding; L Bertilsson; Claes Wahlestedt
The single nucleotide polymorphism T1128C in the signal peptide of neuropeptide Y (NPY) was not identified in a Korean population.
Journal of clinical pharmacy and therapeutics 2002;27(3):211-2.
2002: Lars M Bjorklund; Rosario Sanchez-Pernaute; Sangmi Chung; Therese Andersson; Iris Yin Ching Chen; Kevin St P McNaught; Anna-Liisa Brownell; Bruce G Jenkins; Claes Wahlestedt; Kwang-Soo Kim; Ole Isacson
Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2344-9.
2002: Vladimir I Kashuba; Alexei Protopopov; Sergei M Kvasha; Rinat Z Gizatullin; Claes Wahlestedt; Lev L Kisselev; George Klein; Eugene R Zabarovsky
hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein.
Gene 2002;283(1-2):209-17.
2002: Veronika I Zabarovska; Rinat Z Gizatullin; Ali N Al-Amin; Raf M Podowski; Alexei Protopopov; Sven Löfdahl; Claes Wahlestedt; Gösta Winberg; Vladimir I Kashuba; Ingemar Ernberg; Eugene R Zabarovsky
A new approach to genome mapping and sequencing: slalom libraries.
Nucleic acids research 2002;30(2):E6.
2001: J Li; F Wang; Vladimir I Kashuba; Claes Wahlestedt; E R Zabarovsky
Cloning of deleted sequences (CODE): A genomic subtraction method for enriching and cloning deleted sequences.
BioTechniques 2001;31(4):788, 790, 792-3.
2001: K Sollerbrant; Joacim Elmén; Claes Wahlestedt; Joel Acker; H Leblois-Prehaud; Martine Latta-Mahieu; Patrice Yeh; M Perricaudet
A novel method using baculovirus-mediated gene transfer for production of recombinant adeno-associated virus vectors.
The Journal of general virology 2001;82(Pt 9):2051-60.
2001: Renhai Cao; Ebba Brakenhielm; Claes Wahlestedt; J Thyberg; Yihai Cao
Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6390-5.
2001: Vladimir I Kashuba; Sergei M Kvasha; Alexei Protopopov; Rinat Z Gizatullin; A V Rynditch; Claes Wahlestedt; Wyeth W Wasserman; Eugene R Zabarovsky
Initial isolation and analysis of the human Kv1.7 (KCNA7) gene, a member of the voltage-gated potassium channel gene family.
Gene 2001;268(1-2):115-22.
2001: S P Schrimpf; H Langen; A V Gomes; Claes Wahlestedt
A two-dimensional protein map of Caenorhabditis elegans.
Electrophoresis 2001;22(6):1224-32.
2000: GL Fraser; Amynah Pradhan; Paul B S Clarke; Claes Wahlestedt
Supraspinal antinociceptive response to [D-Pen(2,5)]-enkephalin (DPDPE) is pharmacologically distinct from that to other delta-agonists in the rat.
The Journal of pharmacology and experimental therapeutics 2000;295(3):1135-41.
2000: Liam Good; R Sandberg; Ola Larsson; Peter E Nielsen; Claes Wahlestedt
Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer.
Microbiology (Reading, England) 2000;146 ( Pt 10)():2665-70.
2000: Mary-Rose Hoja; Claes Wahlestedt; Christer Höög
A visual intracellular classification strategy for uncharacterized human proteins.
Experimental cell research 2000;259(1):239-46.
2000: A Vaz Gomes; Claes Wahlestedt
Altered behaviour following RNA interference knockdown of a C. elegans G-protein coupled receptor by ingested double stranded RNA.
European journal of pharmacology 2000;397(2-3):R3-5.
2000: Vladimir I Kashuba; Alexei Protopopov; Raf M Podowski; Rinat Z Gizatullin; Jingfeng Li; George Klein; Claes Wahlestedt; Eugene R Zabarovsky
Isolation and chromosomal localization of a new human retinoblastoma binding protein 2 homologue 1a (RBBP2H1A).
European journal of human genetics : EJHG 2000;8(6):407-13.
2000: Claes Wahlestedt; Peter Salmi; L Good; Johanna Kela; T Johnsson; T Hökfelt; C Broberger; F Porreca; J Lai; K Ren; Michael H Ossipov; A Koshkin; N Jakobsen; J Skouv; H Oerum; M H Jacobsen; J Wengel
Potent and nontoxic antisense oligonucleotides containing locked nucleic acids.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5633-8.
2000: GL Fraser; J Holmgren; Paul B S Clarke; Claes Wahlestedt
Antisense inhibition of delta-opioid receptor gene function in vivo by peptide nucleic acids.
Molecular pharmacology 2000;57(4):725-31.
2000: Eugene R Zabarovsky; Rinat Z Gizatullin; Raf M Podowski; V V Zabarovska; L Xie; Olga V Muravenko; S Kozyrev; Lev Petrenko; N Skobeleva; Jingfeng Li; Alexei Protopopov; Vladimir I Kashuba; Ingemar Ernberg; Gösta Winberg; Claes Wahlestedt
NotI clones in the analysis of the human genome.
Nucleic acids research 2000;28(7):1635-9.
2000: Peter Salmi; B S Sproat; J Ludwig; R Hale; N Avery; Johanna Kela; Claes Wahlestedt
Dopamine D(2) receptor ribozyme inhibits quinpirole-induced stereotypy in rats.
European journal of pharmacology 2000;388(1):R1-2.
2000: Jingfeng Li; Fuli Wang; Veronika I Zabarovska; Claes Wahlestedt; Eugene R Zabarovsky
Cloning of polymorphisms (COP): enrichment of polymorphic sequences from complex genomes.
Nucleic acids research 2000;28(2):e1.
2000: Alexei Protopopov; Vladimir I Kashuba; Raf M Podowski; Rinat Z Gizatullin; E Sonnhammer; Claes Wahlestedt; Eugene R Zabarovsky
Assignment of the GPR14 gene coding for the G-protein-coupled receptor 14 to human chromosome 17q25.3 by fluorescent in situ hybridization.
Cytogenetics and cell genetics 2000;88(3-4):312-3.
2000: Veronika I Zabarovska; Jinfeng Li; Olga V Muravenko; Ludmila Fedorova; Eleonora Braga; Ingemar Ernberg; Claes Wahlestedt; George Klein; Eugene R Zabarovsky
CIS--cloning of identical sequences between two complex genomes.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2000;8(1):77-84.
1999: A Eriksson; Claes Wahlestedt; K Nordqvist
Isolation of sex-specific cDNAs from fetal mouse brain using mRNA differential display and representational difference analysis.
Brain research. Molecular brain research 1999;74(1-2):91-7.
1999: Vladimir I Kashuba; Rinat Z Gizatullin; Alexei Protopopov; Jinfeng Li; N V Vorobieva; Ludmila Fedorova; Veronika I Zabarovska; Olga V Muravenko; Maria Kost-Alimova; D A Domninsky; Csaba Kiss; R Allikmets; V M Zakharyev; Eleonora Braga; Janos Sumegi; M Lerman; Claes Wahlestedt; Alexander V Zelenin; Denise Sheer; Gösta Winberg; Alexander Graphodatsky ; Lev L Kisselev; George Klein; Eugene R Zabarovsky
Analysis of NotI linking clones isolated from human chromosome 3 specific libraries.
Gene 1999;239(2):259-71.
1999: D O'Donnell; S Ahmad; Claes Wahlestedt; P Walker
Expression of the novel galanin receptor subtype GALR2 in the adult rat CNS: distinct distribution from GALR1.
The Journal of comparative neurology 1999;409(3):469-81.
1999: Claes Wahlestedt; L Good
Antisense oligonucleotides - the way forward.
Current opinion in drug discovery & development 1999;2(2):142-6.
1998: Sultan Ahmad; Dajan O'Donnell; Kemal Payza; Julie Ducharme; D Ménard; William Brown; Ralf Schmidt; Claes Wahlestedt; Shi-Hsiang Shen; Philippe Walker
Cloning and evaluation of the role of rat GALR-2, a novel subtype of galanin receptor, in the control of pain perception.
Annals of the New York Academy of Sciences 1998;863():108-19.
1998: Claes Wahlestedt
Reward for persistence in substance P research.
Science (New York, N.Y.) 1998;281(5383):1624-5.
1997: K Emilsson; Claes Wahlestedt; M K Sun; S Nystedt; Christer Owman; J Sundelin
Vascular effects of proteinase-activated receptor 2 agonist peptide.
Journal of vascular research 1997;34(4):267-72.
1997: M C Pepin; S Y Yue; E Roberts; Claes Wahlestedt; P Walker
Novel "restoration of function" mutagenesis strategy to identify amino acids of the delta-opioid receptor involved in ligand binding.
The Journal of biological chemistry 1997;272(14):9260-7.
1996: M Valiquette; H K Vu; S Y Yue; Claes Wahlestedt; P Walker
Involvement of Trp-284, Val-296, and Val-297 of the human delta-opioid receptor in binding of delta-selective ligands.
The Journal of biological chemistry 1996;271(31):18789-96.
1996: G Weng; Douglas L Feinstein; Donald J Reis; Claes Wahlestedt
Neuropeptide Y receptor gene regulation in mouse adrenocortical Y-1 cells.
Regulatory peptides 1996;63(1):53-6.
1996: XY Sun; X H Zhao; David Erlinge; Lars Edvinsson; B Fallgren; Claes Wahlestedt; Thomas Hedner
Effects of phosphorothioated neuropeptide Y Y1-receptor antisense oligodeoxynucleotide in conscious rats and in human vessels.
British journal of pharmacology 1996;118(1):131-6.
1996: X Sun; J You; Thomas Hedner; David Erlinge; B Fellström; H Yoo; Claes Wahlestedt; Lars Edvinsson
alpha-Trinositol: a functional (non-receptor) neuropeptide Y antagonist in vasculature.
The Journal of pharmacy and pharmacology 1996;48(1):77-84.
1995: G Weng; Frances Yee; P Michl; Donald J Reis; Claes Wahlestedt
Studies on neuropeptide Y receptors in a mouse adrenocortical cell line.
Molecular pharmacology 1995;48(1):9-14.
1995: XY Sun; Lars Edvinsson; H Yoo; Claes Wahlestedt; Thomas Hedner
Effects of some novel D-myo-inositol-phosphate derivatives on binding and sympathetic transmission.
Journal of cardiovascular pharmacology 1995;25(5):696-704.
1995: David Erlinge; J You; Claes Wahlestedt; Lars Edvinsson
Characterisation of an ATP receptor mediating mitogenesis in vascular smooth muscle cells.
European journal of pharmacology 1995;289(1):135-49.
1994: Akira Akabayashi; Y Watanabe; Claes Wahlestedt; Bruce S McEwen; X Paez; Sarah F Leibowitz
Hypothalamic neuropeptide Y, its gene expression and receptor activity: relation to circulating corticosterone in adrenalectomized rats.
Brain research 1994;665(2):201-12.
1994: Frances Yee; H Ericson; Donald J Reis; Claes Wahlestedt
Cellular uptake of intracerebroventricularly administered biotin- or digoxigenin-labeled antisense oligodeoxynucleotides in the rat.
Cellular and molecular neurobiology 1994;14(5):475-86.
1994: S Nystedt; K Emilsson; Claes Wahlestedt; J Sundelin
Molecular cloning of a potential proteinase activated receptor.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9208-12.
1994: Mikael Adner; David Erlinge; Leif G Salford; Frances Yee; Claes Wahlestedt; Lars Edvinsson
Human endothelin ETA receptor antisense oligodeoxynucleotides inhibit endothelin-1 evoked vasoconstriction.
European journal of pharmacology 1994;261(3):281-4.
1994: H Yoo; B Fallgren; A Lindahl; Claes Wahlestedt
Characterization of specific binding sites for alpha-trinositol (D-myo-inositol 1,2,6-trisphosphate) in rat tissues.
European journal of pharmacology 1994;268(1):55-63.
1994: K M Standifer; C C Chien; Claes Wahlestedt; G P Brown; Gavril W Pasternak
Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor.
Neuron 1994;12(4):805-10.
1994: Claes Wahlestedt
Antisense oligonucleotide strategies in neuropharmacology.
Trends in pharmacological sciences 1994;15(2):42-6.
1994: Akira Akabayashi; Claes Wahlestedt; Jesline T Alexander; Sarah F Leibowitz
Specific inhibition of endogenous neuropeptide Y synthesis in arcuate nucleus by antisense oligonucleotides suppresses feeding behavior and insulin secretion.
Brain research. Molecular brain research 1994;21(1-2):55-61.
1993: Z Zukowska-Grojec; M Golczynska; G H Shen; A Torres-Duarte; M Haass; Claes Wahlestedt; Adam K Myers
Modulation of vascular function by neuropeptide Y during development of hypertension in spontaneously hypertensive rats.
Pediatric nephrology (Berlin, Germany) 1993;7(6):845-52.
1993: David Erlinge; H Yoo; Lars Edvinsson; Donald J Reis; Claes Wahlestedt
Mitogenic effects of ATP on vascular smooth muscle cells vs. other growth factors and sympathetic cotransmitters.
The American journal of physiology 1993;265(4 Pt 2):H1089-97.
1993: Elena Jazin; H Yoo; A G Blomqvist; Frances Yee; G Weng; M W Walker; J Salon; Dan Larhammar; Claes Wahlestedt
A proposed bovine neuropeptide Y (NPY) receptor cDNA clone, or its human homologue, confers neither NPY binding sites nor NPY responsiveness on transfected cells.
Regulatory peptides 1993;47(3):247-58.
1993: David Erlinge; Lars Edvinsson; J Brunkwall; Frances Yee; Claes Wahlestedt
Human neuropeptide Y Y1 receptor antisense oligodeoxynucleotide specifically inhibits neuropeptide Y-evoked vasoconstriction.
European journal of pharmacology 1993;240(1):77-80.
1993: Steven O Franklin; K Elliott; Y S Zhu; Claes Wahlestedt; Charles E Inturrisi
Quantitation of NMDA receptor (NMDAR1) mRNA levels in the adult and developing rat CNS.
Brain research. Molecular brain research 1993;19(1-2):93-100.
1993: Claes Wahlestedt; Eugene Golanov; S Yamamoto; Frances Yee; H Ericson; H Yoo; C E Inturrisi; Donald J Reis
Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions.
Nature 1993;363(6426):260-3.
1993: Z Zukowska-Grojec; nhu nguyen; Carol A. Colton; J Yao; G H Shen; Adam K Myers; Claes Wahlestedt
Mitogenic effect of neuropeptide Y in rat vascular smooth muscle cells.
Peptides 1993;14(2):263-8.
1993: L Grundemar; Claes Wahlestedt; Z Y Wang
Neuropeptide Y suppresses the neurogenic inflammatory response in the rabbit eye; mode of action.
Regulatory peptides 1993;43(1-2):57-64.
1993: Claes Wahlestedt; E M Pich; George F Koob; Frances Yee; Markus Heilig
Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides.
Science (New York, N.Y.) 1993;259(5094):528-31.
1993: Claes Wahlestedt; Donald J Reis
Neuropeptide Y-related peptides and their receptors--are the receptors potential therapeutic drug targets?
Annual review of pharmacology and toxicology 1993;33():309-52.
1993: D Larhammar; A G Blomqvist; Claes Wahlestedt
The receptor revolution--multiplicity of G-protein-coupled receptors.
Drug design and discovery 1993;9(3-4):179-88.
1992: M K Sun; Claes Wahlestedt; Donald J Reis
Action of externally applied ATP on rat reticulospinal vasomotor neurons.
European journal of pharmacology 1992;224(1):93-6.
1992: Claes Wahlestedt; Donald J Reis; H Yoo; M Adamsson; D Andersson; Lars Edvinsson
A novel inositol phosphate selectively inhibits vasoconstriction evoked by the sympathetic co-transmitters neuropeptide Y (NPY) and adenosine triphosphate (ATP).
Neuroscience letters 1992;143(1-2):123-6.
1992: M K Sun; Claes Wahlestedt; Donald J Reis
Inositol hexakisphosphate excites rat medullary sympathoexcitatory neurons in vivo.
European journal of pharmacology 1992;215(1):9-16.
1992: Soundar Regunathan; Donald J Reis; Claes Wahlestedt
Specific binding of inositol hexakisphosphate (phytic acid) to adrenal chromaffin cell membranes and effects on calcium-dependent catecholamine release.
Biochemical pharmacology 1992;43(6):1331-6.
1992: J B Sundelin; D M Provvedini; Claes Wahlestedt; H Laurell; J S Pohl; P A Peterson
Molecular cloning of the murine substance K and substance P receptor genes.
European journal of biochemistry / FEBS 1992;203(3):625-31.
1992: L Grundemar; S E Jonas; N Mörner; Edward D Högestätt; Claes Wahlestedt; Rolf Håkanson
Characterization of vascular neuropeptide Y receptors.
British journal of pharmacology 1992;105(1):45-50.
1992: Claes Wahlestedt; Soundar Regunathan; Donald J Reis
Identification of cultured cells selectively expressing Y1-, Y2-, or Y3-type receptors for neuropeptide Y/peptide YY.
Life sciences 1992;50(4):PL7-12.
1991: Markus Heilig; L Edvinsson; Claes Wahlestedt
Effects of intracerebroventricular D-myo-inositol-1,2,6-trisphosphate (PP56), a proposed neuropeptide Y (NPY) antagonist, on locomotor activity, food intake, central effects of NPY and NPY-receptor binding.
European journal of pharmacology 1991;209(1-2):27-32.
1991: G H Shen; L Grundemar; Z Zukowska-Grojec; Rolf Håkanson; Claes Wahlestedt
C-terminal neuropeptide Y fragments are mast cell-dependent vasodepressor agents.
European journal of pharmacology 1991;204(3):249-56.
1991: Sue A Aicher; M Springston; S B Berger; Donald J Reis; Claes Wahlestedt
Receptor-selective analogs demonstrate NPY/PYY receptor heterogeneity in rat brain.
Neuroscience letters 1991;130(1):32-6.
1991: L Grundemar; Claes Wahlestedt; Donald J Reis
Neuropeptide Y acts at an atypical receptor to evoke cardiovascular depression and to inhibit glutamate responsiveness in the brainstem.
The Journal of pharmacology and experimental therapeutics 1991;258(2):633-8.
1991: Claes Wahlestedt; F Karoum; george jaskiw; R J Wyatt; D Larhammar; R Ekman; Donald J Reis
Cocaine-induced reduction of brain neuropeptide Y synthesis dependent on medial prefrontal cortex.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2078-82.
1991: L Grundemar; Claes Wahlestedt; Donald J Reis
Long-lasting inhibition of the cardiovascular responses to glutamate and the baroreceptor reflex elicited by neuropeptide Y injected into the nucleus tractus solitarius of the rat.
Neuroscience letters 1991;122(1):135-9.
1991: Claes Wahlestedt
Strategies to detect heterologously expressed tachykinin receptors in Xenopus Oocytes.
Annals of the New York Academy of Sciences 1991;632():116-22.
1990: L Grundemar; Claes Wahlestedt; G H Shen; Z Zukowska-Grojec; Rolf Håkanson
Biphasic blood pressure response to neuropeptide Y in anesthetized rats.
European journal of pharmacology 1990;179(1-2):83-7.
1990: Gary Brooker; T Seki; D Croll; Claes Wahlestedt
Calcium wave evoked by activation of endogenous or exogenously expressed receptors in Xenopus oocytes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2813-7.
1990: Claes Wahlestedt; R Håkanson; C A Vaz; Z Zukowska-Grojec
Norepinephrine and neuropeptide Y: vasoconstrictor cooperation in vivo and in vitro.
The American journal of physiology 1990;258(3 Pt 2):R736-42.
1990: Claes Wahlestedt; J A Blendy; Kenneth J Kellar; Markus Heilig; E Widerlöv; R Ekman
Electroconvulsive shocks increase the concentration of neocortical and hippocampal neuropeptide Y (NPY)-like immunoreactivity in the rat.
Brain research 1990;507(1):65-8.
1990: Markus Heilig; L Vècséi; Claes Wahlestedt; Christer Alling; E Widerlöv
Effects of centrally administered neuropeptide Y (NPY) and NPY13-36 on the brain monoaminergic systems of the rat.
Journal of neural transmission. General section 1990;79(3):193-208.
1990: Claes Wahlestedt; L Grundemar; Rolf Håkanson; Markus Heilig; G H Shen; Z Zukowska-Grojec; Donald J Reis
Neuropeptide Y receptor subtypes, Y1 and Y2.
Annals of the New York Academy of Sciences 1990;611():7-26.
1990: O Häppölä; Claes Wahlestedt; R Ekman; Seppo Soinila; Pertti Panula; R Håkanson
Peptide YY-like immunoreactivity in sympathetic neurons of the rat.
Neuroscience 1990;39(1):225-30.
1989: Claes Wahlestedt; R Ekman; Markus Heilig; E Widerlöv
Effects of psychoactive drugs on delta sleep-inducing peptide concentrations in rat brain.
European journal of pharmacology 1989;159(3):285-9.
1989: Claes Wahlestedt; R Ekman; E Widerlöv
Neuropeptide Y (NPY) and the central nervous system: distribution effects and possible relationship to neurological and psychiatric disorders.
Progress in neuro-psychopharmacology & biological psychiatry 1989;13(1-2):31-54.
1988: Markus Heilig; Claes Wahlestedt; E Widerlöv
Neuropeptide Y (NPY)-induced suppression of activity in the rat: evidence for NPY receptor heterogeneity and for interaction with alpha-adrenoceptors.
European journal of pharmacology 1988;157(2-3):205-13.
1988: Helen M Cox; Alan W Cuthbert; R Håkanson; Claes Wahlestedt
The effect of neuropeptide Y and peptide YY on electrogenic ion transport in rat intestinal epithelia.
The Journal of physiology 1988;398():65-80.
1988: Markus Heilig; Claes Wahlestedt; R Ekman; E Widerlöv
Antidepressant drugs increase the concentration of neuropeptide Y (NPY)-like immunoreactivity in the rat brain.
European journal of pharmacology 1988;147(3):465-7.
1988: E Widerlöv; L H Lindström; Claes Wahlestedt; R Ekman
Neuropeptide Y and peptide YY as possible cerebrospinal fluid markers for major depression and schizophrenia, respectively.
Journal of psychiatric research 1988;22(1):69-79.
1987: P Kannisto; Rolf Håkanson; Christer Owman; G Schmidt; Claes Wahlestedt
GABA suppresses stimulation-induced release of [3H]-noradrenaline from sympathetic nerve fibres in bovine ovarian follicles.
Journal of autonomic pharmacology 1987;7(4):339-47.
1987: Claes Wahlestedt; G Skagerberg; R Ekman; Markus Heilig; F Sundler; R Håkanson
Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat.
Brain research 1987;417(1):33-8.
1987: R Håkanson; B Beding; R Ekman; Markus Heilig; Claes Wahlestedt; F Sundler
Multiple tachykinin pools in sensory nerve fibres in the rabbit iris.
Neuroscience 1987;21(3):943-50.
1987: Lars-Torsten Larsson; G Malmfors; Claes Wahlestedt; S Leander; R Håkanson
Hirschsprung's disease: a comparison of the nervous control of ganglionic and aganglionic smooth muscle in vitro.
Journal of pediatric surgery 1987;22(5):431-5.
1987: Claes Wahlestedt; B Wohlfart; R Håkanson
Effects of neuropeptide Y (NPY) on isolated guinea-pig heart.
Acta physiologica Scandinavica 1987;129(4):459-63.
1986: R Ekman; Claes Wahlestedt; G Böttcher; F Sundler; R Håkanson; Pertti Panula
Peptide YY-like immunoreactivity in the central nervous system of the rat.
Regulatory peptides 1986;16(2):157-68.
1986: Claes Wahlestedt; B Beding; R Ekman; Olli Oksala; J Stjernschantz; R Håkanson
Calcitonin gene-related peptide in the eye: release by sensory nerve stimulation and effects associated with neurogenic inflammation.
Regulatory peptides 1986;16(2):107-15.
1986: Claes Wahlestedt; N Yanaihara; R Håkanson
Evidence for different pre-and post-junctional receptors for neuropeptide Y and related peptides.
Regulatory peptides 1986;13(3-4):307-18.
1986: R Håkanson; Claes Wahlestedt; E Ekblad; L Edvinsson; F Sundler
Neuropeptide Y: coexistence with noradrenaline. Functional implications.
Progress in brain research 1986;68():279-87.
1986: F Sundler; R Håkanson; E Ekblad; R Uddman; Claes Wahlestedt
Neuropeptide Y in the peripheral adrenergic and enteric nervous systems.
International review of cytology 1986;102():243-69.
1986: Claes Wahlestedt; R Håkanson
Effects of neuropeptide Y (NPY) at the sympathetic neuroeffector junction. Can pre- and postjunctional receptors be distinguished?
Medical biology 1986;64(2-3):85-8.
1985: Claes Wahlestedt; G Bynke; B Beding; P von Leithner; R Håkanson
Neurogenic mechanisms in control of the rabbit iris sphincter muscle.
European journal of pharmacology 1985;117(3):303-9.
1985: Claes Wahlestedt; L Edvinsson; E Ekblad; R Håkanson
Neuropeptide Y potentiates noradrenaline-evoked vasoconstriction: mode of action.
The Journal of pharmacology and experimental therapeutics 1985;234(3):735-41.
1985: L Edvinsson; R Håkanson; S Steen; F Sundler; R Uddman; Claes Wahlestedt
Innervation of human omental arteries and veins and vasomotor response to noradrenaline, neuropeptide Y, substance P and vasoactive intestinal peptide.
Regulatory peptides 1985;12(1):67-79.
1985: E Ekblad; R Håkanson; F Sundler; Claes Wahlestedt
Galanin: neuromodulatory and direct contractile effects on smooth muscle preparations.
British journal of pharmacology 1985;86(1):241-6.
1985: Claes Wahlestedt; G Skagerberg; R Håkanson; F Sundler; H Wada; T Watanabe
Spinal projections of hypothalamic histidine decarboxylase-immunoreactive neurones.
Agents and actions 1985;16(3-4):231-3.
1985: G Bynke; Claes Wahlestedt; B Beding; R Håkanson
Pupillary supersensitivity to substance P following prolonged treatment with tetrodotoxin or substance P antagonists.
European journal of pharmacology 1985;108(3):217-23.
1985: E Ekblad; Claes Wahlestedt; R Håkanson; F Sundler; T Watanabe; H Wada
Is histamine a neurotransmitter in the gut? Evidence from histidine decarboxylase immunocytochemistry.
Acta physiologica Scandinavica 1985;123(2):225-7.
1984: Claes Wahlestedt; G Bynke; R Håkanson
Pupillary constriction by bradykinin and capsaicin: mode of action.
European journal of pharmacology 1984;106(3):577-83.
1984: L Edvinsson; E Ekblad; R Håkanson; Claes Wahlestedt
Neuropeptide Y potentiates the effect of various vasoconstrictor agents on rabbit blood vessels.
British journal of pharmacology 1984;83(2):519-25.
1984: E Ekblad; L Edvinsson; Claes Wahlestedt; R Uddman; R Håkanson; F Sundler
Neuropeptide Y co-exists and co-operates with noradrenaline in perivascular nerve fibers.
Regulatory peptides 1984;8(3):225-35.
1983: R Håkanson; Claes Wahlestedt; L Westlin; S Vallgren; F Sundler
Neuronal histamine in the gut wall releasable by gastrin and cholecystokinin.
Neuroscience letters 1983;42(3):305-10.
1982: J Ekström; Claes Wahlestedt
Supersensitivity to substance P and physalaemin in rat salivary glands after denervation or decentralization.
Acta physiologica Scandinavica 1982;115(4):437-46.