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Walter Wahli

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José Iglesias; Shawon Lahiri; Angela McDonald; Daniel Metzger; Sylvain Pradevand; Marc Prentki; Frank Reimann; Catherine Roger; Guy A Rutter; Bernard Thorens; David Vallois; Sebastian Barg; Claire Bonal; Pierre Chambon; Marie-Bernard Debril; Fiona Gribble; Pedro Herrera; Akadiri Yessoufou; Walter Wahli
PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
Walter Wahli; Liliane Michalik
PPARs at the crossroads of lipid signaling and inflammation.
Xiaojia Ge; Craig McFarlane; Mridula Sharma; Anuradha Vajjala; Walter Wahli; Ravi Kambadur
Lack of Smad3 signaling leads to impaired skeletal muscle regeneration.

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All Publications

2012: José Iglesias; Shawon Lahiri; Angela McDonald; Daniel Metzger; Sylvain Pradevand; Marc Prentki; Frank Reimann; Catherine Roger; Guy A Rutter; Bernard Thorens; David Vallois; Sebastian Barg; Claire Bonal; Pierre Chambon; Marie-Bernard Debril; Fiona Gribble; Pedro Herrera; Akadiri Yessoufou; Walter Wahli
PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
The Journal of clinical investigation 2012;122(11):4105-17.
2012: Walter Wahli; Liliane Michalik
PPARs at the crossroads of lipid signaling and inflammation.
Trends in endocrinology and metabolism: TEM 2012;23(7):351-63.
2012: Xiaojia Ge; Craig McFarlane; Mridula Sharma; Anuradha Vajjala; Walter Wahli; Ravi Kambadur
Lack of Smad3 signaling leads to impaired skeletal muscle regeneration.
American journal of physiology. Endocrinology and metabolism 2012;303(1):E90-102.
2012: Sabeera Bonala; Harikumar Arigela; Sudarsanareddy Lokireddy; Craig McFarlane; Mridula Sharma; Serena Teng; Walter Wahli; Ravi Kambadur
Peroxisome proliferator-activated receptor β/δ induces myogenesis by modulating myostatin activity.
The Journal of biological chemistry 2012;287(16):12935-51.
2012: L Serrano-Marco; Walter Wahli; E Barroso; I El Kochairi; Liliane Michalik; Xavier Palomer; Manuel Vázquez-Carrera
The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells.
Diabetologia 2012;55(3):743-51.
2012: Radina Kostadinova; Alexandra Montagner; Pierre Desreumaux; David Dombrowicz; Sébastien Fleury; Erwan Gouranton; Hervé Guillou; Walter Wahli
GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation.
Cell & bioscience 2012;2(1):34.
2012: Estelle Woldt; Audrey Bednarczyk; Christian Boudier; Véronique Bruban; Pierre Chambon; Maria Eugenia Chollet; Fanny Coudane; Zeina El Asmar; Sophie Foppolo; Joachim Herz; Rachel L Matz; Daniel Metzger; Mohamed Mlih; Ewa Ninio; Christine Schaeffer; Jérome Terrand; Danièle Thiersé; Alain Van Dorsselaer; Walter Wahli; Philippe Boucher
The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells.
Nature communications 2012;3():1077.
2011: Alexandra Montagner; Gianpaolo Rando; Gwendoline Degueurce; Nicolas Leuenberger; Liliane Michalik; Walter Wahli
New insights into the role of PPARs.
Prostaglandins, leukotrienes, and essential fatty acids 2011;85(5):235-43.
2011: Xiaojia Ge; Sudarsanareddy Lokireddy; Craig McFarlane; Zhi Hui Ng; Mridula Sharma; Chek Kun Tan; Nguan Soon Tan; Anuradha Vajjala; Walter Wahli; Ravi Kambadur
Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts.
Cell research 2011;21(11):1591-604.
2011: Ilhem El Kochairi; Christine Lohmann; Christian M Matter; Alexandra Montagner; Gianpaolo Rando; Walter Wahli
Beneficial effects of combinatorial micronutrition on body fat and atherosclerosis in mice.
Cardiovascular research 2011;91(4):732-41.
2011: Gianpaolo Rando; Walter Wahli
Sex differences in nuclear receptor-regulated liver metabolic pathways.
Biochimica et biophysica acta 2011;1812(8):964-73.
2011: Lucía Serrano-Marco; Walter Wahli; Ilhem El Kochairi; Liliane Michalik; Xavier Palomer; Ricardo Rodríguez-Calvo; Manuel Vázquez-Carrera
Activation of peroxisome proliferator-activated receptor-β/-δ (PPAR-β/-δ) ameliorates insulin signaling and reduces SOCS3 levels by inhibiting STAT3 in interleukin-6-stimulated adipocytes.
Diabetes 2011;60(7):1990-9.
2011: Philipp Kulozik; Allan Jones; Frits Mattijssen; Adam J Rose; Anja Reimann; Daniela Strzoda; Stefan Kleinsorg; Christina Raupp; Jürgen Kleinschmidt; Karin Müller-Decker; Walter Wahli; Carsten Sticht; Norbert Gretz; Christian von Loeffelholz; Martin Stockmann; Andreas Pfeiffer; Sigrid Stöhr; Geesje M Dallinga-Thie; Peter P Nawroth; Mauricio Berriel Diaz; Stephan Herzig
Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.
Cell metabolism 2011;13(4):389-400.
2011: Frédéric Gachon; Nicolas Leuenberger; Thierry Claudel; Pascal Gos; Céline Jouffe; Fabienne Fleury-Olela; Xavier de Mollerat du Jeu; Walter Wahli; Ueli Schibler
Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPARalpha) activity.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(12):4794-9.
2011: Chek Kun Tan; Nicolas Leuenberger; Ming Jie Tan; Yew Wai Yan; Yinghui Chen; Ravi Kambadur; Walter Wahli; Nguan Soon Tan
Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet.
Diabetes 2011;60(2):464-76.
2011: David Alvarez-Guardia; Xavier Palomer; Teresa Coll; Lucía Serrano; Ricardo Rodríguez-Calvo; Mercy M Davidson; Manuel Merlos; Ilhem El Kochairi; Liliane Michalik; Walter Wahli; Manuel Vázquez-Carrera
PPARβ/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells.
Biochimica et biophysica acta 2011;1811(2):59-67.
2011: Nicolas Deblon; Vincenzo Di Marzo; Michelangelo Foti; Vincent Geenen; Jean-Jacques Legros; Stefania Petrosino; Fabiana Piscitelli; Lucie Bourgoin; Anne-Lise Bussier; Aurélie Caillon; Christelle Veyrat-Durebex; Walter Wahli; Françoise Rohner-Jeanrenaud
Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats.
PloS one 2011;6(9):e25565.
2011: Michal Hensler; Zuzana Macek Jilkova; Jan Kopecky; Daniel Meztger; Walter Wahli; Kristina Bardova; Pierre Chambon; Pavel Flachs
The inhibition of fat cell proliferation by n-3 fatty acids in dietary obese mice.
Lipids in health and disease 2011;10():128.
2010: Nicolas Rotman; Walter Wahli
PPAR modulation of kinase-linked receptor signaling in physiology and disease.
Physiology (Bethesda, Md.) 2010;25(3):176-85.
2010: Alexandros Vegiopoulos; Karin Müller-Decker; Daniela Strzoda; Iris Schmitt; Evgeny Chichelnitskiy; Anke Ostertag; Mauricio Berriel Diaz; Jan Rozman; Martin Hrabe de Angelis; Rolf M Nüsing; Carola W Meyer; Walter Wahli; Martin Klingenspor; Stephan Herzig
Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes.
Science (New York, N.Y.) 2010;328(5982):1158-61.
2009: Christine Lohmann; Nicola Schäfer; Tobias von Lukowicz; M A Sokrates Stein; Jan Borén; Sabine Rütti; Walter Wahli; Marc Y Donath; Thomas F Lüscher; Christian M Matter
Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets.
Atherosclerosis 2009;207(2):360-7.
2009: Nicolas Leuenberger; Sylvain Pradervand; Walter Wahli
Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice.
The Journal of clinical investigation 2009;119(10):3138-48.
2009: Nicolas Rotman; Walter Wahli
Fatty acid synthesis and PPARalpha hand in hand.
Chemistry & biology 2009;16(8):801-2.
2009: Han Chung Chong; Ming Jie Tan; Virginie Philippe; Siew Hwey Tan; Chek Kun Tan; Chee Wai Ku; Yan Yih Goh; Walter Wahli; Liliane Michalik; Nguan Soon Tan
Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing.
The Journal of cell biology 2009;184(6):817-31.
2009: Andrée Demers; Véronique Caron; Amélie Rodrigue-Way; Walter Wahli; Huy Ong; André Tremblay
A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages.
PloS one 2009;4(11):e7728.
2008: Ricardo Rodríguez-Calvo; Lucía Serrano; Teresa Coll; Norman Moullan; Rosa M Sánchez; Manuel Merlos; Xavier Palomer; Juan C Laguna; Liliane Michalik; Walter Wahli; Manuel Vázquez-Carrera
Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2.
Diabetes 2008;57(8):2149-57.
2008: Aruna Jahoor; Rashila Patel; Amanda Bryan; Catherine Do; Jay Krier; Chase Watters; Walter Wahli; Guigen Li; Simon C Williams; Kendra P Rumbaugh
Peroxisome proliferator-activated receptors mediate host cell proinflammatory responses to Pseudomonas aeruginosa autoinducer.
Journal of bacteriology 2008;190(13):4408-15.
2008: Walter Wahli
A gut feeling of the PXR, PPAR and NF-kappaB connection.
Journal of internal medicine 2008;263(6):613-9.
2008: David Brawand; Walter Wahli; Henrik Kaessmann
Loss of egg yolk genes in mammals and the origin of lactation and placentation.
PLoS biology 2008;6(3):e63.
2008: Walter Wahli
PPAR gamma: ally and foe in bone metabolism.
Cell metabolism 2008;7(3):188-90.
2008: Liliane Michalik; Walter Wahli
PPARs Mediate Lipid Signaling in Inflammation and Cancer.
PPAR research 2008;2008():134059.
2007: Haibin Wang; Huirong Xie; Xiaofei Sun; Susanne Tranguch; Hao Zhang; Xiangxu Jia; Dingzhi Wang; Sanjoy K Das; Béatrice Desvergne; Walter Wahli; Raymond DuBois; Sudhansu K Dey
Stage-specific integration of maternal and embryonic peroxisome proliferator-activated receptor delta signaling is critical to pregnancy success.
The Journal of biological chemistry 2007;282(52):37770-82.
2007: Silvia I Anghel; Elodie Bedu; Celine Delucinge Vivier; Patrick Descombes; Béatrice Desvergne; Walter Wahli
Adipose tissue integrity as a prerequisite for systemic energy balance: a critical role for peroxisome proliferator-activated receptor gamma.
The Journal of biological chemistry 2007;282(41):29946-57.
2007: Nguan Soon Tan; Guillaume Icre; Alexandra Montagner; Béatrice Bordier-ten-Heggeler; Walter Wahli; Liliane Michalik
The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration.
Molecular and cellular biology 2007;27(20):7161-75.
2007: Liliane Michalik; Walter Wahli
Peroxisome proliferator-activated receptors (PPARs) in skin health, repair and disease.
Biochimica et biophysica acta 2007;1771(8):991-8.
2007: Jerome N Feige; Laurent Gelman; Daniel Rossi; Vincent Zoete; Raphaël Métivier; Cicerone Tudor; Silvia I Anghel; Aurélien Grosdidier; Caroline Lathion; Yves Engelborghs; Olivier Michielin; Walter Wahli; Béatrice Desvergne
The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis.
The Journal of biological chemistry 2007;282(26):19152-66.
2007: Silvia I Anghel; Walter Wahli
Fat poetry: a kingdom for PPAR gamma.
Cell research 2007;17(6):486-511.
2007: Antoine Berry; Patricia Balard; Agnès Coste; David Olagnier; Céline Lagane; Hélène Authier; Françoise Benoit-Vical; Jean-Claude Lepert; Jean-Paul Séguéla; Jean-François Magnaval; Pierre Chambon; Daniel Metzger; Béatrice Desvergne; Walter Wahli; Johan Auwerx; Bernard Pipy
IL-13 induces expression of CD36 in human monocytes through PPARgamma activation.
European journal of immunology 2007;37(6):1642-52.
2007: Liliane Michalik; Walter Wahli
Guiding ligands to nuclear receptors.
Cell 2007;129(4):649-51.
2007: Stéphane Mandard; Rinke Stienstra; Pascal Escher; Nguan Soon Tan; I Kim; F J Gonzalez; Walter Wahli; Béatrice Desvergne; Michael Müller; Sander Kersten
Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors.
Cellular and molecular life sciences : CMLS 2007;64(9):1145-57.
2007: Rinke Stienstra; Stéphane Mandard; Nguan Soon Tan; Walter Wahli; Christian Trautwein; Terrilyn A Richardson; Elgin Lichtenauer-Kaligis; Sander Kersten; Michael Müller
The Interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver.
Journal of hepatology 2007;46(5):869-77.
2007: Arup Kumar Indra; Eduardo Castaneda; Maria Cristina Antal; Ming Jiang; Nadia Messaddeq; Xiangjun Meng; Christiane V Loehr; Patricio Gariglio; Shigeaki Kato; Walter Wahli; Béatrice Desvergne; Daniel Metzger; Pierre Chambon
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
The Journal of investigative dermatology 2007;127(5):1250-60.
2007: Liliane Michalik; Vincent Zoete; Grigorios Krey; Aurélien Grosdidier; Laurent Gelman; Pierre Chodanowski; Jerome N Feige; Béatrice Desvergne; Walter Wahli; Olivier Michielin
Combined simulation and mutagenesis analyses reveal the involvement of key residues for peroxisome proliferator-activated receptor alpha helix 12 dynamic behavior.
The Journal of biological chemistry 2007;282(13):9666-77.
2007: Cicerone Tudor; Jerome N Feige; Harikishore Pingali; Vidya Bhushan Lohray; Walter Wahli; Béatrice Desvergne; Yves Engelborghs; Laurent Gelman
Association with coregulators is the major determinant governing peroxisome proliferator-activated receptor mobility in living cells.
The Journal of biological chemistry 2007;282(7):4417-26.
2006: Dingzhi Wang; Haibin Wang; Yong Guo; Wei Ning; Sharada Katkuri; Walter Wahli; Béatrice Desvergne; Sudhansu K Dey; Raymond DuBois
Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19069-74.
2006: Liliane Michalik; Johan Auwerx; Joel P Berger; V Krishna Chatterjee; Christopher K Glass; Frank J Gonzalez; Paul A Grimaldi; Takashi Kadowaki; Mitchell Lazar; Stephen O'Rahilly; Colin N A Palmer; Jorge Plutzky; Janardan K Reddy; Bruce M Spiegelman; Bart Staels; Walter Wahli
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.
Pharmacological reviews 2006;58(4):726-41.
2006: Roberta Avallone; Andrée Demers; Amélie Rodrigue-Way; Kim Bujold; Diala Harb; Silvia Anghel; Walter Wahli; Sylvie Marleau; Huy Ong; André Tremblay
A growth hormone-releasing peptide that binds scavenger receptor CD36 and ghrelin receptor up-regulates sterol transporters and cholesterol efflux in macrophages through a peroxisome proliferator-activated receptor gamma-dependent pathway.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3165-78.
2006: Michael Schuler; Faisal Ali; Céline Chambon; Delphine Duteil; Jean-Marc Bornert; Aubry Tardivel; Béatrice Desvergne; Walter Wahli; Pierre Chambon; Daniel Metzger
PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes.
Cell metabolism 2006;4(5):407-14.
2006: Guillaume Icre; Walter Wahli; Liliane Michalik
Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2006;11(1):30-5.
2006: Claude Knauf; Jennifer Rieusset; Marc Foretz; Patrice Cani; Marc Uldry; Masaya Hosokawa; Estelle Martinez; Matthieu Bringart; Aurélie Waget; Sander Kersten; Béatrice Desvergne; Sandrine Gremlich; Walter Wahli; Josiane Seydoux; Nathalie M Delzenne; Bernard Thorens; Rémy Burcelin
Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.
Endocrinology 2006;147(9):4067-78.
2006: Frédéric VARNAT; Béatrice Bordier-Ten Heggeler; Philippe Grisel; Nathalie Boucard; Irène Corthésy-Theulaz; Walter Wahli; Béatrice Desvergne
PPARbeta/delta regulates paneth cell differentiation via controlling the hedgehog signaling pathway.
Gastroenterology 2006;131(2):538-53.
2006: Laurence Canaple; Juliette Rambaud; Ouria Dkhissi-Benyahya; Béatrice Rayet; Nguan Soon Tan; Liliane Michalik; Franck Delaunay; Walter Wahli; Vincent Laudet
Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.
Molecular endocrinology (Baltimore, Md.) 2006;20(8):1715-27.
2006: Béatrice Desvergne; Liliane Michalik; Walter Wahli
Transcriptional regulation of metabolism.
Physiological reviews 2006;86(2):465-514.
2006: Karim Nadra; Silvia I Anghel; Elisabeth Joye; Nguan Soon Tan; Sharmila Basu-Modak; Didier Trono; Walter Wahli; Béatrice Desvergne
Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta.
Molecular and cellular biology 2006;26(8):3266-81.
2006: Liliane Michalik; Walter Wahli
Involvement of PPAR nuclear receptors in tissue injury and wound repair.
The Journal of clinical investigation 2006;116(3):598-606.
2006: Jerome N Feige; Laurent Gelman; Liliane Michalik; Béatrice Desvergne; Walter Wahli
From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions.
Progress in lipid research 2006;45(2):120-59.
2006: Ferhana Y Ali; Karine Egan; garret fitzgerald; Béatrice Desvergne; Walter Wahli; David Bishop-Bailey; Timothy D Warner; Jane A Mitchell
Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts.
American journal of respiratory cell and molecular biology 2006;34(2):242-6.
2006: Stéphane Mandard; Fokko Zandbergen; Esther van Straten; Walter Wahli; Folkert Kuipers; Michael Müller; Sander Kersten
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity.
The Journal of biological chemistry 2006;281(2):934-44.
2006: Laurent Gelman; Jerome N Feige; Cicerone Tudor; Yves Engelborghs; Walter Wahli; Béatrice Desvergne
Integrating nuclear receptor mobility in models of gene regulation.
Nuclear receptor signaling 2006;4():e010.
2005: Marie-Bernard Debril; Laurent Dubuquoy; Jerome N Feige; Walter Wahli; Béatrice Desvergne; Johan Auwerx; Laurent Gelman
Scaffold attachment factor B1 directly interacts with nuclear receptors in living cells and represses transcriptional activity.
Journal of molecular endocrinology 2005;35(3):503-17.
2005: Zhong-Zhou Yang; Oliver Tschopp; Nicolas Di-Poï; Elisabeth Bruder; Anne Baudry; Bettina Dümmler; Walter Wahli; Brian A Hemmings
Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice.
Molecular and cellular biology 2005;25(23):10407-18.
2005: Fokko Zandbergen; Stéphane Mandard; Pascal Escher; Nguan Soon Tan; David Patsouris; Tim Jatkoe; Sandra Rojas-Caro; Steve Madore; Walter Wahli; Sherrie Tafuri; Michael Müller; Sander Kersten
The G0/G1 switch gene 2 is a novel PPAR target gene.
The Biochemical journal 2005;392(Pt 2):313-24.
2005: Nicolas Di-Poï; Béatrice Desvergne; Liliane Michalik; Walter Wahli
Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins.
The Journal of biological chemistry 2005;280(46):38700-10.
2005: David M Mutch; Walter Wahli; Gary Williamson
Nutrigenomics and nutrigenetics: the emerging faces of nutrition.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(12):1602-16.
2005: Jerome N Feige; Daniel Sage; Walter Wahli; Béatrice Desvergne; Laurent Gelman
PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs.
Microscopy research and technique 2005;68(1):51-8.
2005: Liliane Michalik; Jerome N Feige; Laurent Gelman; Thierry Pedrazzini; H Keller; Béatrice Desvergne; Walter Wahli
Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2335-48.
2005: Elodie Bedu; Walter Wahli; Béatrice Desvergne
Peroxisome proliferator-activated receptor beta/delta as a therapeutic target for metabolic diseases.
Expert opinion on therapeutic targets 2005;9(4):861-73.
2005: Emmanuel Letavernier; Joëlle Perez; Elisabeth Joye; Agnès Bellocq; Bruno Fouqueray; Jean-Philippe Haymann; Didier Heudes; Walter Wahli; Béatrice Desvergne; Laurent Baud
Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure.
Journal of the American Society of Nephrology : JASN 2005;16(8):2395-402.
2005: Daniel Metzger; Takeshi Imai; Ming Jiang; R Takukawa; Béatrice Desvergne; Walter Wahli; Pierre Chambon
Functional role of RXRs and PPARgamma in mature adipocytes.
Prostaglandins, leukotrienes, and essential fatty acids 2005;73(1):51-8.
2005: Raphael Genolet; Sander Kersten; Olivier Braissant; Stéphane Mandard; Nguan Soon Tan; Philipp Bucher; Béatrice Desvergne; Liliane Michalik; Walter Wahli
Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.
The Journal of biological chemistry 2005;280(25):24143-52.
2005: Jerome N Feige; Laurent Gelman; Cicerone Tudor; Yves Engelborghs; Walter Wahli; Béatrice Desvergne
Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand.
The Journal of biological chemistry 2005;280(18):17880-90.
2005: Nguan Soon Tan; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics.
The Journal of biological chemistry 2005;280(18):18163-70.
2005: Christel Rousseaux; Bruno Lefebvre; Laurent Dubuquoy; Philippe Lefebvre; Olivier Romano; Johan Auwerx; Daniel Metzger; Walter Wahli; Béatrice Desvergne; Gian Carlo Naccari; Philippe CHAVATTE; Amaury Farce; Philippe Bulois; Antoine Cortot; Jean-Frédéric Colombel; Pierre Desreumaux
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma.
The Journal of experimental medicine 2005;201(8):1205-15.
2005: Jeremy A Sellers; Li Hou; Daniel R Schoenberg; Silvia R Batistuzzo de Medeiros; Walter Wahli; Gregory S Shelness
Microsomal triglyceride transfer protein promotes the secretion of Xenopus laevis vitellogenin A1.
The Journal of biological chemistry 2005;280(14):13902-5.
2005: Laurent Gelman; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Kinase signaling cascades that modulate peroxisome proliferator-activated receptors.
Current opinion in cell biology 2005;17(2):216-22.
2005: Anna Planavila; Ricardo Rodríguez-Calvo; Mireia Jové; Liliane Michalik; Walter Wahli; Juan C Laguna; Manuel Vázquez-Carrera
Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes.
Cardiovascular research 2005;65(4):832-41.
2005: Nicolas Di-Poï; Chuan Young Ng; Nguan Soon Tan; Zhongzhou Yang; Brian A Hemmings; Béatrice Desvergne; Liliane Michalik; Walter Wahli
Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.
Molecular and cellular biology 2005;25(5):1696-712.
2005: Nguan Soon Tan; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes.
The Journal of steroid biochemistry and molecular biology 2005;93(2-5):99-105.
2005: Stanko Skrtic; Linda Carlsson; Anna Ljungberg; Daniel Lindén; Liliane Michalik; Walter Wahli; Jan Oscarsson
Decreased expression of peroxisome proliferator-activated receptor alpha and liver fatty acid binding protein after partial hepatectomy of rats and mice.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(1):33-40.
2005: Radina Kostadinova; Walter Wahli; Liliane Michalik
PPARs in diseases: control mechanisms of inflammation.
Current medicinal chemistry 2005;12(25):2995-3009.
2005: Sandrine Gremlich; Christopher Nolan; Raphael Roduit; Rémy Burcelin; Marie-Line Peyot; Viviane Delghingaro-Augusto; Béatrice Desvergne; Liliane Michalik; Marc Prentki; Walter Wahli
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.
Endocrinology 2005;146(1):375-82.
2004: Raphael Genolet; Walter Wahli; Liliane Michalik
PPARs as drug targets to modulate inflammatory responses?
Current drug targets. Inflammation and allergy 2004;3(4):361-75.
2004: Nicolas Di-Poï; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Functions of peroxisome proliferator-activated receptors (PPAR) in skin homeostasis.
Lipids 2004;39(11):1093-9.
2004: Nguan Soon Tan; Liliane Michalik; Nicolas Di-Poï; Chuan Young Ng; Nicolas Mermod; Anita B Roberts; Béatrice Desvergne; Walter Wahli
Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression.
The EMBO journal 2004;23(21):4211-21.
2004: Jennifer Rieusset; Josiane Seydoux; Silvia I Anghel; Pascal Escher; Liliane Michalik; Nguan Soon Tan; Daniel Metzger; Pierre Chambon; Walter Wahli; Béatrice Desvergne
Altered growth in male peroxisome proliferator-activated receptor gamma (PPARgamma) heterozygous mice: involvement of PPARgamma in a negative feedback regulation of growth hormone action.
Molecular endocrinology (Baltimore, Md.) 2004;18(10):2363-77.
2004: Stéphane Mandard; Fokko Zandbergen; Nguan Soon Tan; Pascal Escher; David Patsouris; Wolfgang Koenig; Robert Kleemann; Arjen Bakker; Frank Veenman; Walter Wahli; Michael Müller; Sander Kersten
The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment.
The Journal of biological chemistry 2004;279(33):34411-20.
2004: Man Mao-Qiang; Ashley J Fowler; Matthias Schmuth; Peggy Lau; Sandra Chang; Barbara E Brown; Arthur H Moser; Liliane Michalik; Béatrice Desvergne; Walter Wahli; Mei Li; Daniel Metzger; Pierre H Chambon; Peter M Elias; Kenneth R Feingold
Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation.
The Journal of investigative dermatology 2004;123(2):305-12.
2004: David Patsouris; Stéphane Mandard; Peter J Voshol; Pascal Escher; Nguan Soon Tan; Louis M Havekes; Wolfgang Koenig; Winfried März; Sherrie Tafuri; Walter Wahli; Michael Müller; Sander Kersten
PPARalpha governs glycerol metabolism.
The Journal of clinical investigation 2004;114(1):94-103.
2004: Béatrice Desvergne; Liliane Michalik; Walter Wahli
Be fit or be sick: peroxisome proliferator-activated receptors are down the road.
Molecular endocrinology (Baltimore, Md.) 2004;18(6):1321-32.
2004: Annemieke Ijpenberg; Nguan Soon Tan; Laurent Gelman; Sander Kersten; Josiane Seydoux; Jianming Xu; Daniel Metzger; Laurence Canaple; Pierre Chambon; Walter Wahli; Béatrice Desvergne
In vivo activation of PPAR target genes by RXR homodimers.
The EMBO journal 2004;23(10):2083-91.
2004: Takeshi Imai; Reiko Takakuwa; Sandra Marchand; Emilie Dentz; Jean-Marc Bornert; Nadia Messaddeq; Olivia Wendling; Manuel Mark; Béatrice Desvergne; Walter Wahli; Pierre Chambon; Daniel Metzger
Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4543-7.
2004: David M Mutch; Pascale Anderle; Muriel Fiaux; Robert Mansourian; Karine Vidal; Walter Wahli; Gary Williamson; Matthew-Alan Roberts
Regional variations in ABC transporter expression along the mouse intestinal tract.
Physiological genomics 2004;17(1):11-20.
2004: Nguan Soon Tan; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptor-beta as a target for wound healing drugs.
Expert opinion on therapeutic targets 2004;8(1):39-48.
2004: Nguan Soon Tan; Liliane Michalik; Nicolas Di-Poï; Béatrice Desvergne; Walter Wahli
Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healing.
Biochemical Society transactions 2004;32(Pt 1):97-102.
2004: Liliane Michalik; Béatrice Desvergne; Walter Wahli
Peroxisome-proliferator-activated receptors and cancers: complex stories.
Nature reviews. Cancer 2004;4(1):61-70.
2004: Elena Sanguino; Miguel Ramón; Liliane Michalik; Walter Wahli; Marta Alegret; Rosa M Sánchez; Manuel Vázquez-Carrera; Juan C Laguna
Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha.
Biochemical pharmacology 2004;67(1):157-66.
2004: Mireia Jové; Joel Salla; Anna Planavila; Agatha Cabrero; Liliane Michalik; Walter Wahli; Juan C Laguna; Manuel Vázquez-Carrera
Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone.
Journal of lipid research 2004;45(1):113-23.
2003: Nicolas Di-Poï; Liliane Michalik; Nguan Soon Tan; Béatrice Desvergne; Walter Wahli
The anti-apoptotic role of PPARbeta contributes to efficient skin wound healing.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):257-65.
2003: Liliane Michalik; Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptors beta/delta: emerging roles for a previously neglected third family member.
Current opinion in lipidology 2003;14(2):129-35.
2003: Karine Hellemans; Krista Rombouts; Erik Quartier; Andrea S Dittié; Andreas Knorr; Liliane Michalik; Vera Rogiers; Frans Schuit; Walter Wahli; Albert Geerts
PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation.
Journal of lipid research 2003;44(2):280-95.
2003: Nguan Soon Tan; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?
American journal of clinical dermatology 2003;4(8):523-30.
2003: Karine Hellemans; Liliane Michalik; Andrea Dittie; Andreas Knorr; Krista Rombouts; Jan De Jong; Carlo Heirman; Erik Quartier; Frans Schuit; Walter Wahli; Albert Geerts
Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells.
Gastroenterology 2003;124(1):184-201.
2003: Masoumeh Jalouli; Linda Carlsson; Caroline Améen; Daniel Lindén; Anna Ljungberg; Liliane Michalik; Staffan Edén; Walter Wahli; Jan Oscarsson
Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: influence of pituitary and gonadal hormones.
Endocrinology 2003;144(1):101-9.
2002: Jennifer Rieusset; Fethi Touri; Liliane Michalik; Pascal Escher; Béatrice Desvergne; Eric Niesor; Walter Wahli
A new selective peroxisome proliferator-activated receptor gamma antagonist with antiobesity and antidiabetic activity.
Molecular endocrinology (Baltimore, Md.) 2002;16(11):2628-44.
2002: Nicolas Di-Poï; Nguan Soon Tan; Liliane Michalik; Walter Wahli; Béatrice Desvergne
Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.
Molecular cell 2002;10(4):721-33.
2002: Nguan Soon Tan; Natacha S Shaw; Nicolas Vinckenbosch; Peng Liu; Rubina Yasmin; Béatrice Desvergne; Walter Wahli; Noa Noy
Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription.
Molecular and cellular biology 2002;22(14):5114-27.
2002: Sylvie Fauconnet; Isabelle Lascombe; Eric Chabannes; Gérard-Louis Adessi; Béatrice Desvergne; Walter Wahli; Hugues Bittard
Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells.
The Journal of biological chemistry 2002;277(26):23534-43.
2002: AK Hihi; Liliane Michalik; Walter Wahli
PPARs: transcriptional effectors of fatty acids and their derivatives.
Cellular and molecular life sciences : CMLS 2002;59(5):790-8.
2002: Walter Wahli
Peroxisome proliferator-activated receptors (PPARs): from metabolic control to epidermal wound healing.
Swiss medical weekly 2002;132(7-8):83-91.
2002: Paolo Ciana; Elisabetta Vegeto; Miguel Beato; Pierre Chambon; Jan-�ke GUSTAFSSON; Malcolm Parker; Walter Wahli; Stefano Di Giovine
Looking at nuclear receptors from the heights of Erice. Workshop on nuclear receptor structure and function.
EMBO reports 2002;3(2):125-9.
2002: Liliane Michalik; Béatrice Desvergne; Christine Dreyer; Mathilde Gavillet; Ricardo Laurini; Walter Wahli
PPAR expression and function during vertebrate development.
The International journal of developmental biology 2002;46(1):105-14.
2001: Nguan Soon Tan; Liliane Michalik; Noa Noy; Rubina Yasmin; C Pacot; M Heim; B Flühmann; Béatrice Desvergne; Walter Wahli
Critical roles of PPAR beta/delta in keratinocyte response to inflammation.
Genes & development 2001;15(24):3263-77.
2001: Pascal Escher; Olivier Braissant; Sharmila Basu-Modak; Liliane Michalik; Walter Wahli; Béatrice Desvergne
Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.
Endocrinology 2001;142(10):4195-202.
2001: Sander Kersten; Stéphane Mandard; Pascal Escher; FJ Gonzalez; Sherrie Tafuri; Béatrice Desvergne; Walter Wahli
The peroxisome proliferator-activated receptor alpha regulates amino acid metabolism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):1971-8.
2001: Liliane Michalik; Béatrice Desvergne; Nguan Soon Tan; Sharmila Basu-Modak; Pascal Escher; Jennifer Rieusset; J M Peters; G Kaya; FJ Gonzalez; Jozsef Zakany; Daniel Metzger; Pierre Chambon; D Duboule; Walter Wahli
Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice.
The Journal of cell biology 2001;154(4):799-814.
2001: Hélène Poirier; Isabelle Niot; Marie-Claude Monnot; Olivier Braissant; C Meunier-Durmort; Philippe Costet; Thierry Pineau; Walter Wahli; T M Willson; Philippe Besnard
Differential involvement of peroxisome-proliferator-activated receptors alpha and delta in fibrate and fatty-acid-mediated inductions of the gene encoding liver fatty-acid-binding protein in the liver and the small intestine.
The Biochemical journal 2001;355(Pt 2):481-8.
2001: Pierre Desreumaux; Laurent Dubuquoy; Sophie Nutten; M Peuchmaur; W Englaro; Kristina Schoonjans; B Derijard; Béatrice Desvergne; Walter Wahli; P Chambon; M D Leibowitz; Jean-Frédéric Colombel; Johan Auwerx
Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies.
The Journal of experimental medicine 2001;193(7):827-38.
2000: G Lazennec; Laurence Canaple; D Saugy; Walter Wahli
Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators.
Molecular endocrinology (Baltimore, Md.) 2000;14(12):1962-75.
2000: Sander Kersten; Stéphane Mandard; Nguan Soon Tan; Pascal Escher; Daniel Metzger; Pierre Chambon; FJ Gonzalez; Béatrice Desvergne; Walter Wahli
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene.
The Journal of biological chemistry 2000;275(37):28488-93.
2000: D Robyr; A Gegonne; A P Wolffe; Walter Wahli
Determinants of vitellogenin B1 promoter architecture. HNF3 and estrogen responsive transcription within chromatin.
The Journal of biological chemistry 2000;275(36):28291-300.
2000: I Lascombe; D Beffa; UT Rüegg; J Tarradellas; Walter Wahli
Estrogenic activity assessment of environmental chemicals using in vitro assays: identification of two new estrogenic compounds.
Environmental health perspectives 2000;108(7):621-9.
2000: Sander Kersten; Béatrice Desvergne; Walter Wahli
Roles of PPARs in health and disease.
Nature 2000;405(6785):421-4.
2000: Pascal Escher; Walter Wahli
Peroxisome proliferator-activated receptors: insight into multiple cellular functions.
Mutation research 2000;448(2):121-38.
2000: D Robyr; A P Wolffe; Walter Wahli
Nuclear hormone receptor coregulators in action: diversity for shared tasks.
Molecular endocrinology (Baltimore, Md.) 2000;14(3):329-47.
2000: Liliane Michalik; Béatrice Desvergne; Sharmila Basu-Modak; Nguan Soon Tan; Walter Wahli
Nuclear hormone receptors and mouse skin homeostasis: implication of PPARbeta.
Hormone research 2000;54(5-6):263-8.
2000: Sander Kersten; Walter Wahli
Peroxisome proliferator activated receptor agonists.
EXS 2000;89():141-51.
1999: Sharmila Basu-Modak; Olivier Braissant; Pascal Escher; Béatrice Desvergne; Paul Honegger; Walter Wahli
Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cell cultures.
The Journal of biological chemistry 1999;274(50):35881-8.
1999: Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptors: nuclear control of metabolism.
Endocrine reviews 1999;20(5):649-88.
1999: P Bernard; Hervé Goudonnet; Yves Artur; Béatrice Desvergne; Walter Wahli
Activation of the mouse TATA-less and human TATA-containing UDP-glucuronosyltransferase 1A1 promoters by hepatocyte nuclear factor 1.
Molecular pharmacology 1999;56(3):526-36.
1999: PR Devchand; AK Hihi; M Perroud; W D Schleuning; Bruce M Spiegelman; Walter Wahli
Chemical probes that differentially modulate peroxisome proliferator-activated receptor alpha and BLTR, nuclear and cell surface receptors for leukotriene B(4).
The Journal of biological chemistry 1999;274(33):23341-8.
1999: Sander Kersten; Josiane Seydoux; J M Peters; F J Gonzalez; Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting.
The Journal of clinical investigation 1999;103(11):1489-98.
1999: PR Devchand; Annemieke Ijpenberg; B Devesvergne; Walter Wahli
PPARs: nuclear receptors for fatty acids, eicosanoids, and xenobiotics.
Advances in experimental medicine and biology 1999;469():231-6.
1999: Walter Wahli; PR Devchand; Annemieke Ijpenberg; Béatrice Desvergne
Fatty acids, eicosanoids, and hypolipidemic agents regulate gene expression through direct binding to peroxisome proliferator-activated receptors.
Advances in experimental medicine and biology 1999;447():199-209.
1998: Monika Tsai-Pflugfelder; Susan Gasser; Walter Wahli
Functional interaction between the estrogen receptor and CTF1: analysis of the vitellogenin gene B1 promoter in yeast.
Molecular endocrinology (Baltimore, Md.) 1998;12(10):1525-41.
1998: D Marilley; D Robyr; C Schild-Poulter; Walter Wahli
Regulation of the vitellogenin gene B1 promoter after transfer into hepatocytes in primary cultures.
Molecular and cellular endocrinology 1998;141(1-2):79-93.
1998: Olivier Braissant; Walter Wahli
Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development.
Endocrinology 1998;139(6):2748-54.
1998: Béatrice Desvergne; Annemieke Ijpenberg; PR Devchand; Walter Wahli
The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signalling.
The Journal of steroid biochemistry and molecular biology 1998;65(1-6):65-74.
1997: Annemieke Ijpenberg; Elisabeth Jeannin; Walter Wahli; Béatrice Desvergne
Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element.
The Journal of biological chemistry 1997;272(32):20108-17.
1997: Hélène Poirier; Olivier Braissant; Isabelle Niot; Walter Wahli; Philippe Besnard
9-cis-retinoic acid enhances fatty acid-induced expression of the liver fatty acid-binding protein gene.
FEBS letters 1997;412(3):480-4.
1997: S R Batistuzzo de Medeiros; Grigorios Krey; AK Hihi; Walter Wahli
Functional interactions between the estrogen receptor and the transcription activator Sp1 regulate the estrogen-dependent transcriptional activity of the vitellogenin A1 io promoter.
The Journal of biological chemistry 1997;272(29):18250-60.
1997: T Masmoudi; A K Hihi; M Vázquez; Yves Artur; Béatrice Desvergne; Walter Wahli; Hervé Goudonnet
Transcriptional regulation by triiodothyronine of the UDP-glucuronosyltransferase family 1 gene complex in rat liver. Comparison with induction by 3-methylcholanthrene.
The Journal of biological chemistry 1997;272(27):17171-5.
1997: H Keller; PR Devchand; M Perroud; Walter Wahli
PPAR alpha structure-function relationships derived from species-specific differences in responsiveness to hypolipidemic agents.
Biological chemistry 1997;378(7):651-5.
1997: Grigorios Krey; Olivier Braissant; F L'Horset; Eric Kalkhoven; M Perroud; Malcolm G Parker; Walter Wahli
Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay.
Molecular endocrinology (Baltimore, Md.) 1997;11(6):779-91.
1996: T Lemberger; Olivier Braissant; Cristiana E Juge-Aubry; H Keller; R Saladin; B Staels; J Auwerx; Albert G Burger; Christoph A Meier; Walter Wahli
PPAR tissue distribution and interactions with other hormone-signaling pathways.
Annals of the New York Academy of Sciences 1996;804():231-51.
1996: PR Devchand; H Keller; J M Peters; M Vazquez; F J Gonzalez; Walter Wahli
The PPARalpha-leukotriene B4 pathway to inflammation control.
Nature 1996;384(6604):39-43.
1996: A Shalev; C A Siegrist-Kaiser; Paul M Yen; Walter Wahli; Albert G Burger; William W Chin; Christoph A Meier
The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin.
Endocrinology 1996;137(10):4499-502.
1996: T Lemberger; R Saladin; M Vázquez; F Assimacopoulos; B Staels; Béatrice Desvergne; Walter Wahli; J Auwerx
Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm.
The Journal of biological chemistry 1996;271(3):1764-9.
1996: T Lemberger; Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology.
Annual review of cell and developmental biology 1996;12():335-63.
1996: Olivier Braissant; F Foufelle; C Scotto; Michel Dauça; Walter Wahli
Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat.
Endocrinology 1996;137(1):354-66.
1995: A Alevizopoulos; Yves Dusserre; Monika Tsai-Pflugfelder; T von der Weid; Walter Wahli; Nicolas Mermod
A proline-rich TGF-beta-responsive transcriptional activator interacts with histone H3.
Genes & development 1995;9(24):3051-66.
1995: E Roulet; Marie-Therese Armentero; G Krey; Blaise Corthésy; Christine Dreyer; Nicolas Mermod; Walter Wahli
Regulation of the DNA-binding and transcriptional activities of Xenopus laevis NFI-X by a novel C-terminal domain.
Molecular and cellular biology 1995;15(10):5552-62.
1995: Kristina Schoonjans; M Watanabe; H Suzuki; Abderrahim Mahfoudi; G Krey; Walter Wahli; P Grimaldi; Bart Staels; T Yamamoto; Johan Auwerx
Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter.
The Journal of biological chemistry 1995;270(33):19269-76.
1995: Cristiana E Juge-Aubry; A Gorla-Bajszczak; Agnès Pernin; T Lemberger; Walter Wahli; Albert G Burger; Christoph A Meier
Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for retinoid X receptor. Possible role of a leucine zipper-like heptad repeat.
The Journal of biological chemistry 1995;270(30):18117-22.
1995: H Keller; F Givel; M Perroud; Walter Wahli
Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements.
Molecular endocrinology (Baltimore, Md.) 1995;9(7):794-804.
1995: B ten Heggeler-Bordier; C Schild-Poulter; S Chapel; Walter Wahli
Fate of linear and supercoiled multinucleosomic templates during transcription.
The EMBO journal 1995;14(11):2561-9.
1995: Abderrahim Mahfoudi; E Roulet; S Dauvois; M G Parker; Walter Wahli
Specific mutations in the estrogen receptor change the properties of antiestrogens to full agonists.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4206-10.
1995: Walter Wahli; Olivier Braissant; Béatrice Desvergne
Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more....
Chemistry & biology 1995;2(5):261-6.
1995: G Krey; A Mahfoudi; Walter Wahli
Functional interactions of peroxisome proliferator-activated receptor, retinoid-X receptor, and Sp1 in the transcriptional regulation of the acyl-coenzyme-A oxidase promoter.
Molecular endocrinology (Baltimore, Md.) 1995;9(2):219-31.
1995: S B Nunez; Jeffrey A Medin; H Keller; K Wang; Keiko Ozato; Walter Wahli; James H Segars
Retinoid X receptor beta and peroxisome proliferator-activated receptor activate an estrogen response element.
Recent progress in hormone research 1995;50():409-16.
1994: Jean-René Cardinaux; S Chapel; Walter Wahli
Complex organization of CTF/NF-I, C/EBP, and HNF3 binding sites within the promoter of the liver-specific vitellogenin gene.
The Journal of biological chemistry 1994;269(52):32947-56.
1994: T Lemberger; B Staels; R Saladin; Béatrice Desvergne; J Auwerx; Walter Wahli
Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids.
The Journal of biological chemistry 1994;269(40):24527-30.
1994: Francois Claret; S Chapel; J Garcés; Monika Tsai-Pflugfelder; C Bertholet; David J Shapiro; Riccardo Wittek; Walter Wahli
Two functional forms of the Xenopus laevis estrogen receptor translated from a single mRNA species.
The Journal of biological chemistry 1994;269(19):14047-55.
1994: D Marilley; Abderrahim Mahfoudi; Walter Wahli
Gene transfer into Xenopus hepatocytes: transcriptional regulation by members of the nuclear receptor superfamily.
Molecular and cellular endocrinology 1994;101(1-2):227-36.
1994: H Ellinger-Ziegelbauer; A K Hihi; V Laudet; H Keller; Walter Wahli; Christine Dreyer
FTZ-F1-related orphan receptors in Xenopus laevis: transcriptional regulators differentially expressed during early embryogenesis.
Molecular and cellular biology 1994;14(4):2786-97.
1993: G Krey; H Keller; A Mahfoudi; J Medin; K Ozato; Christine Dreyer; Walter Wahli
Xenopus peroxisome proliferator activated receptors: genomic organization, response element recognition, heterodimer formation with retinoid X receptor and activation by fatty acids.
The Journal of steroid biochemistry and molecular biology 1993;47(1-6):65-73.
1993: H Keller; Abderrahim Mahfoudi; Christine Dreyer; A K Hihi; J Medin; K Ozato; Walter Wahli
Peroxisome proliferator-activated receptors and lipid metabolism.
Annals of the New York Academy of Sciences 1993;684():157-73.
1993: James H Segars; Michael S Marks; S Hirschfeld; P H Driggers; E Martinez; J F Grippo; Myles Brown; Walter Wahli; Keiko Ozato
Inhibition of estrogen-responsive gene activation by the retinoid X receptor beta: evidence for multiple inhibitory pathways.
Molecular and cellular biology 1993;13(4):2258-68.
1993: H Keller; Christine Dreyer; J Medin; A Mahfoudi; K Ozato; Walter Wahli
Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2160-4.
1993: C Schild; Francois Claret; Walter Wahli; Alan P Wolffe
A nucleosome-dependent static loop potentiates estrogen-regulated transcription from the Xenopus vitellogenin B1 promoter in vitro.
The EMBO journal 1993;12(2):423-33.
1993: Christine Dreyer; H Keller; Abderrahim Mahfoudi; V Laudet; G Krey; Walter Wahli
Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR).
Biology of the cell / under the auspices of the European Cell Biology Organization 1993;77(1):67-76.
1992: Christine Dreyer; G Krey; H Keller; F Givel; G Helftenbein; Walter Wahli
Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors.
Cell 1992;68(5):879-87.
1992: B ten Heggeler-Bordier; Walter Wahli; M Adrian; Andrzej Stasiak; Jacques Dubochet
The apical localization of transcribing RNA polymerases on supercoiled DNA prevents their rotation around the template.
The EMBO journal 1992;11(2):667-72.
1991: M C Lebeau; G Alvarez-Bolado; Walter Wahli; Stefan Catsicas
PCR driven DNA-DNA competitive hybridization: a new method for sensitive differential cloning.
Nucleic acids research 1991;19(17):4778.
1991: E Martinez; Yves Dusserre; Walter Wahli; Nicolas Mermod
Synergistic transcriptional activation by CTF/NF-I and the estrogen receptor involves stabilized interactions with a limiting target factor.
Molecular and cellular biology 1991;11(6):2937-45.
1991: Walter Wahli; E Martinez
Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(9):2243-9.
1991: M C Lebeau; G Alvarez-Bolado; Olivier Braissant; Walter Wahli; Stefan Catsicas
Ribosomal protein L27 is identical in chick and rat.
Nucleic acids research 1991;19(6):1337.
1991: E Martinez; F Givel; Walter Wahli
A common ancestor DNA motif for invertebrate and vertebrate hormone response elements.
The EMBO journal 1991;10(2):263-8.
1991: Blaise Corthésy; Irène Corthésy-Theulaz; Jean-René Cardinaux; Walter Wahli
A liver protein fraction regulating hormone-dependent in vitro transcription from the vitellogenin genes induces their expression in Xenopus oocytes.
Molecular endocrinology (Baltimore, Md.) 1991;5(2):159-69.
1990: M Adrian; B ten Heggeler-Bordier; Walter Wahli; Andrzej Stasiak; A Stasiak; Jacques Dubochet
Direct visualization of supercoiled DNA molecules in solution.
The EMBO journal 1990;9(13):4551-4.
1990: Blaise Corthésy; Francois Claret; Walter Wahli
Estrogen receptor level determines sex-specific in vitro transcription from the Xenopus vitellogenin promoter.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):7878-82.
1990: Blaise Corthésy; P Léonnard; Walter Wahli
Transcriptional potentiation of the vitellogenin B1 promoter by a combination of both nucleosome assembly and transcription factors: an in vitro dissection.
Molecular and cellular biology 1990;10(8):3926-33.
1989: Blaise Corthésy; Jean-René Cardinaux; Francois Claret; Walter Wahli
A nuclear factor I-like activity and a liver-specific repressor govern estrogen-regulated in vitro transcription from the Xenopus laevis vitellogenin B1 promoter.
Molecular and cellular biology 1989;9(12):5548-62.
1989: E Martinez; Walter Wahli
Cooperative binding of estrogen receptor to imperfect estrogen-responsive DNA elements correlates with their synergistic hormone-dependent enhancer activity.
The EMBO journal 1989;8(12):3781-91.
1989: F Tremea; S R Batistuzzo de Medeiros; B ten Heggeler-Bordier; J E Germond; A Seiler-Tuyns; Walter Wahli
Identification of two steroid-responsive promoters of different strength controlled by the same estrogen-responsive element in the 5'-end region of the Xenopus laevis vitellogenin gene A1.
Molecular endocrinology (Baltimore, Md.) 1989;3(10):1596-609.
1989: D N Haefliger; J E Moskaitis; Daniel R Schoenberg; Walter Wahli
Amphibian albumins as members of the albumin, alpha-fetoprotein, vitamin D-binding protein multigene family.
Journal of molecular evolution 1989;29(4):344-54.
1989: Walter Wahli; E Martinez; Blaise Corthésy; Jean-René Cardinaux
cis- and trans-acting elements of the estrogen-regulated vitellogenin gene B1 of Xenopus laevis.
Journal of steroid biochemistry 1989;34(1-6):17-32.
1988: B ten Heggler-Bordier; Francois Claret; Walter Wahli
Immuno-electron microscopic identification of human estrogen receptor-DNA complexes at the estrogen-responsive element and in the first intron of a Xenopus vitellogenin gene.
Journal of molecular biology 1988;204(1):217-20.
1988: S Green; V Kumar; I Theulaz; Walter Wahli; P Chambon
The N-terminal DNA-binding 'zinc finger' of the oestrogen and glucocorticoid receptors determines target gene specificity.
The EMBO journal 1988;7(10):3037-44.
1988: A Seiler-Tuyns; A M Mérillat; D N Haefliger; Walter Wahli
The human estrogen receptor can regulate exogenous but not endogenous vitellogenin gene promoters in a Xenopus cell line.
Nucleic acids research 1988;16(17):8291-305.
1988: I Theulaz; R Hipskind; B ten Heggeler-Bordier; S Green; V Kumar; P Chambon; Walter Wahli
Expression of human estrogen receptor mutants in Xenopus oocytes: correlation between transcriptional activity and ability to form protein-DNA complexes.
The EMBO journal 1988;7(6):1653-60.
1988: Blaise Corthésy; R Hipskind; I Theulaz; Walter Wahli
Estrogen-dependent in vitro transcription from the vitellogenin promoter in liver nuclear extracts.
Science (New York, N.Y.) 1988;239(4844):1137-9.
1987: E Martinez; F Givel; Walter Wahli
The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element.
The EMBO journal 1987;6(12):3719-27.
1987: D Nardelli; F D van het Schip; S Gerber-Huber; J A Haefliger; M Gruber; G Ab; Walter Wahli
Comparison of the organization and fine structure of a chicken and a Xenopus laevis vitellogenin gene.
The Journal of biological chemistry 1987;262(32):15377-85.
1987: D Nardelli; S Gerber-Huber; F D van het Schip; M Gruber; G Ab; Walter Wahli
Vertebrate and nematode genes coding for yolk proteins are derived from a common ancestor.
Biochemistry 1987;26(20):6397-402.
1987: S Gerber-Huber; D Nardelli; J A Haefliger; D N Cooper; F Givel; J E Germond; J Engel; N M Green; Walter Wahli
Precursor-product relationship between vitellogenin and the yolk proteins as derived from the complete sequence of a Xenopus vitellogenin gene.
Nucleic acids research 1987;15(12):4737-60.
1987: J A Haefliger; Jürg Tschopp; D Nardelli; Walter Wahli; H P Kocher; M Tosi; K K Stanley
Complementary DNA cloning of complement C8 beta and its sequence homology to C9.
Biochemistry 1987;26(12):3551-6.
1987: B ten Heggeler-Bordier; R Hipskind; A Seiler-Tuyns; E Martinez; Blaise Corthésy; Walter Wahli
Electron microscopic visualization of protein-DNA interactions at the estrogen responsive element and in the first intron of the Xenopus laevis vitellogenin gene.
The EMBO journal 1987;6(6):1715-20.
1987: D N Cooper; S Gerber-Huber; D Nardelli; J L Schubiger; Walter Wahli
The distribution of the dinucleotide CpG and cytosine methylation in the vitellogenin gene family.
Journal of molecular evolution 1987;25(2):107-15.
1986: A Seiler-Tuyns; P Walker; E Martinez; A M Mérillat; F Givel; Walter Wahli
Identification of estrogen-responsive DNA sequences by transient expression experiments in a human breast cancer cell line.
Nucleic acids research 1986;14(22):8755-70.
1986: J L Schubiger; Walter Wahli
Linkage arrangement in the vitellogenin gene family of Xenopus laevis as revealed by gene segregation analysis.
Nucleic acids research 1986;14(22):8723-34.
1986: J L Schubiger; Walter Wahli
Transposition of a bacterial IS3 element into a Xenopus Vi-element.
Nucleic acids research 1986;14(19):7814.
1985: J L Schubiger; J E Germond; B ten Heggeler; Walter Wahli
The Vi element. A transposon-like repeated DNA sequence interspersed in the vitellogenin locus of Xenopus laevis.
Journal of molecular biology 1985;186(3):491-503.
1985: B ten Heggeler; Walter Wahli
Visualization of RNA polymerase II ternary transcription complexes formed in vitro on a Xenopus laevis vitellogenin gene.
The EMBO journal 1985;4(9):2269-73.
1984: P Walker; J E Germond; M Brown-Luedi; F Givel; Walter Wahli
Sequence homologies in the region preceding the transcription initiation site of the liver estrogen-responsive vitellogenin and apo-VLDLII genes.
Nucleic acids research 1984;12(22):8611-26.
1984: J E Germond; P Walker; B ten Heggeler; M Brown-Luedi; E de Bony; Walter Wahli
Evolution of vitellogenin genes: comparative analysis of the nucleotide sequences downstream of the transcription initiation site of four Xenopus laevis and one chicken gene.
Nucleic acids research 1984;12(22):8595-609.
1984: J Knowland; I Theulaz; C V Wright; Walter Wahli
Injection of partially purified estrogen receptor protein from Xenopus liver nuclei into oocytes activates the silent vitellogenin locus.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(18):5777-81.
1983: G U Ryffel; D B Muellener; S Gerber-Huber; T Wyler; Walter Wahli
Scattering of repetitive DNA sequences in the albumin and vitellogenin gene loci of Xenopus laevis.
Nucleic acids research 1983;11(22):7701-16.
1983: J E Germond; B ten Heggeler; J L Schubiger; P Walker; B Westley; Walter Wahli
Vitellogenin B2 gene in Xenopus laevis: isolation, in vitro transcription and relation to other vitellogenin genes.
Nucleic acids research 1983;11(10):2979-97.
1983: P Walker; M Brown-Luedi; J E Germond; Walter Wahli; F C Meijlink; A D van het Schip; H Roelink; M Gruber; G Ab
Sequence homologies within the 5' end region of the estrogen-controlled vitellogenin gene in Xenopus and chicken.
The EMBO journal 1983;2(12):2271-9.
1982: Walter Wahli; J E Germond; B ten Heggeler; F E May
Vitellogenin genes A1 and B1 are linked in the Xenopus laevis genome.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(22):6832-6.
1981: G U Ryffel; D B Muellener; T Wyler; Walter Wahli; R Weber
Transcription of single-copy vitellogenin gene of Xenopus involves expression of middle repetitive DNA.
Nature 1981;291(5814):429-31.
1980: Walter Wahli; Igor B Dawid; T Wyler; R Weber; G U Ryffel
Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis.
Cell 1980;20(1):107-17.
1980: B K Felber; S Maurhofer; R B Jaggi; T Wyler; Walter Wahli; G U Ryffel; R Weber
Isolation and translation in vitro of four related vitellogenin mRNAs of estrogen-stimulated Xenopus laevis.
European journal of biochemistry / FEBS 1980;105(1):17-24.