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Mark Wainberg

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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HIV-1

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Co-Publications
Name
40
Liang, Chen
39
Kleiman, Lawrence
39
Brenner, Bluma
28
Oliveira, Maureen
26
Moisi, Daniela
25
Salomon, Horacio
24
Quan, Yudong
23
Hiscott, John
20
Brenner, Bluma
19
Rong, Liwei
17
Götte, Matthias
15
Turner, Dan
15
Bour, Stephan
14
Russell, Rodney
13
Tsoukas, Christos

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Publications

TOP 3
Quan Yudong; Liang Chen; Brenner Bluma G; Wainberg Mark A
Multidrug-resistant variants of HIV type 1 (HIV-1) can exist in cells as defective quasispecies and be rescued by superinfection with other defective HIV-1 variants.
Xu Hongtao; Quan Yudong; Brenner Bluma G; Bar-Magen Tamara; Oliveira Maureen; Schader Susan M; Wainberg Mark A
Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine.
Invernizzi Cédric F; Coutsinos Dimitrios; Oliveira Maureen; Moisi Daniela; Brenner Bluma G; Wainberg Mark A
Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C.

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All Publications

2009: Quan Yudong; Liang Chen; Brenner Bluma G; Wainberg Mark A
Multidrug-resistant variants of HIV type 1 (HIV-1) can exist in cells as defective quasispecies and be rescued by superinfection with other defective HIV-1 variants.
The Journal of infectious diseases 2009;200(9):1479-83.
2009: Xu Hongtao; Quan Yudong; Brenner Bluma G; Bar-Magen Tamara; Oliveira Maureen; Schader Susan M; Wainberg Mark A
Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine.
Antimicrobial agents and chemotherapy 2009;53(11):4667-72.
2009: Invernizzi Cédric F; Coutsinos Dimitrios; Oliveira Maureen; Moisi Daniela; Brenner Bluma G; Wainberg Mark A
Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C.
The Journal of infectious diseases 2009;200(8):1202-6.
2009: Colby-Germinario Susan; Rios Adan; Quesada Jorge; Anderson Dallas; Goldstein Allan L; Fossum Theresa; Wainberg Mark A
HIV inactivation by cross-linking of photo-labeled anti-retroviral compounds with HIV reverse transcriptase.
Vaccine 2009;27(44):6137-42.
2009: Turner Dan; Shahar Eduardo; Katchman Eugene; Kedem Eynat; Matus Natasha; Katzir Michal; Hassoun Gamal; Pollack Shimon; Kessner Rivka; Wainberg Mark A; Avidor Boaz
Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel.
Journal of medical virology 2009;81(9):1509-12.
2009: Ntemgwa Michel L; d'Aquin Toni Thomas; Brenner Bluma G; Camacho Ricardo J; Wainberg Mark A
Antiretroviral drug resistance in human immunodeficiency virus type 2.
Antimicrobial agents and chemotherapy 2009;53(9):3611-9.
2009: Rong Liwei; Zhang Jianyong; Lu Jennifer; Pan Qinghua; Lorgeoux René-Pierre; Aloysius Claudette; Guo Fei; Liu Shan-Lu; Wainberg Mark A; Liang Chen
The transmembrane domain of BST-2 determines its sensitivity to down-modulation by human immunodeficiency virus type 1 Vpu.
Journal of virology 2009;83(15):7536-46.
2009: Wainberg Mark A; Martinez-Cajas Jorge L
Sequencing of therapy to avoid resistance and the need for new antiretroviral drugs in the treatment of HIV disease.
Infectious disorders drug targets 2009;9(2):172-90.
2009: Oliveira Maureen; Moisi Daniela; Spira Bonnie; Cox Susan; Brenner Bluma G; Wainberg Mark A
Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations.
Antimicrobial agents and chemotherapy 2009;53(4):1683-5.
2009: Toni Thomas A; Asahchop Eugene L; Moisi Daniela; Ntemgwa Michel; Oliveira Maureen; Masquelier Bernard; Brenner Bluma G; Wainberg Mark A
Detection of human immunodeficiency virus (HIV) type 1 M184V and K103N minority variants in patients with primary HIV infection.
Antimicrobial agents and chemotherapy 2009;53(4):1670-2.
2009: Wainberg Mark A
Criminalizing HIV transmission may be a mistake.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2009;180(6):688.
2009: Coutsinos Dimitrios; Invernizzi Cédric F; Xu Hongtao; Moisi Daniela; Oliveira Maureen; Brenner Bluma G; Wainberg Mark A
Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1.
Journal of virology 2009;83(4):2029-33.
2009: Ntemgwa Michel L; Toni Thomas d'Aquin; Brenner Bluma G; Oliveira Maureen; Asahchop Eugene L; Moisi Daniela; Wainberg Mark A
Nucleoside and nucleotide analogs select in culture for different patterns of drug resistance in human immunodeficiency virus types 1 and 2.
Antimicrobial agents and chemotherapy 2009;53(2):708-15.
2009: Doualla-Bell Florence; Gaolathe Tendani; Avalos Ava; Cloutier Suzanne; Ndwapi Ndwapi; Holcroft Christina; Moffat Howard; Dickinson Diana; Essex Max; Wainberg Mark A; Mine Madisa
Five-year follow up of genotypic resistance patterns in HIV-1 subtype C infected patients in Botswana after failure of thymidine analogue-based regimens.
Journal of the International AIDS Society 2009;12(1):25.
2009: Martinez-Cajas Jorge L; Pai Nitika P; Klein Marina B; Wainberg Mark A
Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (1996-2008).
Journal of the International AIDS Society 2009;12(1):11.
2009: Xu Hong-Tao; Martinez-Cajas Jorge L; Ntemgwa Michel L; Coutsinos Dimitrios; Frankel Fernando A; Brenner Bluma G; Wainberg Mark A
Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance.
Retrovirology 2009;6():14.
2009: Oliveira Maureen; Brenner Bluma G; Wainberg Mark A
Isolation of drug-resistant mutant HIV variants using tissue culture drug selection.
Methods in molecular biology (Clifton, N.J.) 2009;485():427-33.
2008: Dandache Serge; Coburn Craig A; Oliveira Maureen; Allison Timothy J; Holloway M Katharine; Wu Jinzi J; Stranix Brent R; Panchal Chandra; Wainberg Mark A; Vacca Joseph P
PL-100, a novel HIV-1 protease inhibitor displaying a high genetic barrier to resistance: an in vitro selection study.
Journal of medical virology 2008;80(12):2053-63.
2008: Brenner Bluma G; Roger Michel; Moisi Daniela D; Oliveira Maureen; Hardy Isabelle; Turgel Reuven; Charest Hugues; Routy Jean-Pierre; Wainberg Mark A;
Transmission networks of drug resistance acquired in primary/early stage HIV infection.
AIDS (London, England) 2008;22(18):2509-15.
2008: Martinez-Cajas Jorge L; Invernizzi Cédric F; Ntemgwa Michel; Schader Susan M; Wainberg Mark A
The impact of the journalist-to-journalist program on worldwide HIV awareness.
AIDS (London, England) 2008;22(13):1687-8.
2008: Grant Robert M; Hamer Dean; Hope Thomas; Johnston Rowena; Lange Joep; Lederman Michael M; Lieberman Judy; Miller Christopher J; Moore John P; Mosier Donald E; Richman Douglas D; Schooley Robert T; Springer Marty S; Veazey Ronald S; Wainberg Mark A
Whither or wither microbicides?
Science (New York, N.Y.) 2008;321(5888):532-4.
2008: Wilson David P; Coplan Paul M; Wainberg Mark A; Blower Sally M
The paradoxical effects of using antiretroviral-based microbicides to control HIV epidemics.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9835-40.
2008: Ntemgwa Michel; Gill M John; Brenner Bluma G; Moisi Daniela; Wainberg Mark A
Discrepancies in assignment of subtype/recombinant forms by genotyping programs for HIV type 1 drug resistance testing may falsely predict superinfection.
AIDS research and human retroviruses 2008;24(7):995-1002.
2008: Ntemgwa Michel; Toni Thomas D'Aquin; Brenner Bluma G; Routy Jean-Pierre; Moisi Daniela; Oliveira Maureen; Wainberg Mark A
Near full-length genomic analysis of a novel subtype A1/C recombinant HIV type 1 isolate from Canada.
AIDS research and human retroviruses 2008;24(4):655-9.
2008: Wainberg Mark A
HIV transmission should be decriminalized: HIV prevention programs depend on it.
Retrovirology 2008;5():108.
2008: Martinez-Cajas Jorge L; Invernizzi Cédric F; Ntemgwa Michel; Schader Susan M; Wainberg Mark A
Benefits of an educational program for journalists on media coverage of HIV/AIDS in developing countries.
Journal of the International AIDS Society 2008;11(1):2.
2008: Wainberg Mark A; Katabira Elly; Heidari Shirin
Journal of the International AIDS Society: an important step forward.
Journal of the International AIDS Society 2008;11(1):1.
2008: Wainberg Mark A; Jeang Kuan-Teh
25 years of HIV-1 research - progress and perspectives.
BMC medicine 2008;6():31.
2008: Quan Yudong; Brenner Bluma G; Dascal André; Wainberg Mark A
Highly diversified multiply drug-resistant HIV-1 quasispecies in PBMCs: a case report.
Retrovirology 2008;5():43.
2008: Martinez-Cajas Jorge L; Wainberg Mark A
Antiretroviral therapy : optimal sequencing of therapy to avoid resistance.
Drugs 2008;68(1):43-72.
2007: Martinez-Cajas Jorge L; Wainberg Mark A
Protease inhibitor resistance in HIV-infected patients: molecular and clinical perspectives.
Antiviral research 2007;76(3):203-21.
2007: Ntemgwa Michel; Wainberg Mark A; Oliveira Maureen; Moisi Daniela; Lalonde Richard; Micheli Valeria; Brenner Bluma G
Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine.
Antimicrobial agents and chemotherapy 2007;51(11):3861-9.
2007: Dandache Serge; Sévigny Guy; Yelle Jocelyn; Stranix Brent R; Parkin Neil; Schapiro Jonathan M; Wainberg Mark A; Wu Jinzi J
In vitro antiviral activity and cross-resistance profile of PL-100, a novel protease inhibitor of human immunodeficiency virus type 1.
Antimicrobial agents and chemotherapy 2007;51(11):4036-43.
2007: Wainberg Mark A; Clotet Bonaventura
Review: immunologic response to protease inhibitor-based highly active antiretroviral therapy: a review.
AIDS patient care and STDs 2007;21(9):609-20.
2007: Invernizzi Cédric F; Xie Baode; Frankel Fernando A; Feldhammer Matthew; Roy Bibhuti B; Richard Stéphane; Wainberg Mark A
Arginine methylation of the HIV-1 nucleocapsid protein results in its diminished function.
AIDS (London, England) 2007;21(7):795-805.
2007: Brenner Bluma G; Roger Michel; Routy Jean-Pierre; Moisi Daniela; Ntemgwa Michel; Matte Claudine; Baril Jean-Guy; Thomas Rejéan; Rouleau Danielle; Bruneau Julie; Leblanc Roger; Legault Mario; Tremblay Cecile; Charest Hugues; Wainberg Mark A;
High rates of forward transmission events after acute/early HIV-1 infection.
The Journal of infectious diseases 2007;195(7):951-9.
2007: Xie Baode; Invernizzi Cédric F; Richard Stéphane; Wainberg Mark A
Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat Interactions with both cyclin T1 and the Tat transactivation region.
Journal of virology 2007;81(8):4226-34.
2007: Frankel Fernando A; Invernizzi Cédric F; Oliveira Maureen; Wainberg Mark A
Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations.
AIDS (London, England) 2007;21(6):665-75.
2007: Ntemgwa Michel; Brenner Bluma G; Oliveira Maureen; Moisi Daniela; Wainberg Mark A
Natural polymorphisms in the human immunodeficiency virus type 2 protease can accelerate time to development of resistance to protease inhibitors.
Antimicrobial agents and chemotherapy 2007;51(2):604-10.
2007: Gayle Helene; Wainberg Mark A
The 16th International Conference on AIDS: will it leave a legacy?
MedGenMed : Medscape general medicine 2007;9(2):15.
2007: Whitney James B; Wainberg Mark A
Recovery of fitness of a live attenuated simian immunodeficiency virus through compensation in both the coding and non-coding regions of the viral genome.
Retrovirology 2007;4():44.
2007: Frankel Fernando A; Coutsinos Dimitrios; Xu Hongtao; Wainberg Mark A
Kinetics of inhibition of HIV type 1 reverse transcriptase-bearing NRTI-associated mutations by apricitabine triphosphate.
Antiviral chemistry & chemotherapy 2007;18(2):93-101.
2007: Wainberg Mark A; Cahn Pedro; Bethell Richard C; Sawyer James; Cox Susan
Apricitabine: a novel deoxycytidine analogue nucleoside reverse transcriptase inhibitor for the treatment of nucleoside-resistant HIV infection.
Antiviral chemistry & chemotherapy 2007;18(2):61-70.
2007: Gayle Helene; Wainberg Mark A
Impact of the 16th International Conference on AIDS: can these conferences lead to policy change?
Retrovirology 2007;4():13.
2007: Gatignol Anne; Dubuisson Jean; Wainberg Mark A; Cohen Eric A; Darlix Jean-Luc
New pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and flu.
Retrovirology 2007;4():8.
2006: Doualla-Bell Florence; Avalos Ava; Brenner Bluma; Gaolathe Tendani; Mine Madisa; Gaseitsiwe Simani; Oliveira Maureen; Moisi Daniella; Ndwapi Ndwapi; Moffat Howard; Essex Max; Wainberg Mark A
High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens.
Antimicrobial agents and chemotherapy 2006;50(12):4182-5.
2006: Wainberg Mark A
The need to promote public health in the field of illicit drug use.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2006;175(11):1395.
2006: Derdelinckx Inge; Wainberg Mark A; Lange Joep M A; Hill Andrew; Halima Yasmin; Boucher Charles A B
Criteria for drugs used in pre-exposure prophylaxis trials against HIV infection.
PLoS medicine 2006;3(11):e454.
2006: Grant Robert M; Wainberg Mark A
Chemoprophylaxis of HIV infection: moving forward with caution.
The Journal of infectious diseases 2006;194(7):874-6.
2006: Martinez Jorge; Coplan Paul; Wainberg Mark A
Is HIV drug resistance a limiting factor in the development of anti-HIV NNRTI and NRTI-based vaginal microbicide strategies?
Antiviral research 2006;71(2-3):343-50.
2006: Solis Mayra; Wilkinson Peter; Romieu Raphaelle; Hernandez Eduardo; Wainberg Mark A; Hiscott John
Gene expression profiling of the host response to HIV-1 B, C, or A/E infection in monocyte-derived dendritic cells.
Virology 2006;352(1):86-99.
2006: Brenner Bluma G; Oliveira Maureen; Doualla-Bell Florence; Moisi Daniela D; Ntemgwa Michel; Frankel Fernando; Essex Max; Wainberg Mark A
HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture.
AIDS (London, England) 2006;20(9):F9-13.
2006: Doualla-Bell Florence; Avalos Ava; Gaolathe Tendani; Mine Madisa; Gaseitsiwe Simani; Ndwapi Ndwapi; Novitsky Vladimir A; Brenner Bluma; Oliveira Maureen; Moisi Daniella; Moffat Howard; Thior Ibou; Essex Max; Wainberg Mark A
Impact of human immunodeficiency virus type 1 subtype C on drug resistance mutations in patients from Botswana failing a nelfinavir-containing regimen.
Antimicrobial agents and chemotherapy 2006;50(6):2210-3.
2006: Machouf N; Thomas R; Nguyen V K; Trottier B; Boulassel M R; Wainberg M A; Routy J P
Effects of drug resistance on viral load in patients failing antiretroviral therapy.
Journal of medical virology 2006;78(5):608-13.
2006: Turner Dan; Wainberg Mark A
HIV transmission and primary drug resistance.
AIDS reviews 2006;8(1):17-23.
2006: Wainberg Mark A
Twenty-five years of AIDS: where are we now?
MedGenMed : Medscape general medicine 2006;8(4):21.
2006: Whitney James B; Wainberg Mark A
Impaired RNA incorporation and dimerization in live attenuated leader-variants of SIVmac239.
Retrovirology 2006;3():96.
2006: Invernizzi Cédric F; Xie Baode; Richard Stéphane; Wainberg Mark A
PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA.
Retrovirology 2006;3():93.
2006: Wainberg Mark A
The XVI International Conference on AIDS: the place to be!
Retrovirology 2006;3():9.
2005: Guo Xiaofeng; Roy Bibhuti Bhusan; Hu Jing; Roldan Ariel; Wainberg Mark A; Liang Chen
The R362A mutation at the C-terminus of CA inhibits packaging of human immunodeficiency virus type 1 RNA.
Virology 2005;343(2):190-200.
2005: Grant Robert M; Buchbinder Susan; Cates Willard; Clarke Edith; Coates Thomas; Cohen Myron S; Delaney Martin; Flores Guiselly; Goicochea Pedro; Gonsalves Gregg; Harrington Mark; Lama Javier R; MacQueen Kathleen M; Moore John P; Peterson Leigh; Sanchez Jorge; Thompson Melanie; Wainberg Mark A
AIDS. Promote HIV chemoprophylaxis research, don't prevent it.
Science (New York, N.Y.) 2005;309(5744):2170-1.
2005: Desfosses Yan; Solis Mayra; Sun Qiang; Grandvaux Nathalie; Van Lint Carine; Burny Arsene; Gatignol Anne; Wainberg Mark A; Lin Rongtuan; Hiscott John
Regulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins.
Journal of virology 2005;79(14):9180-91.
2005: Frankel Fernando A; Marchand Bruno; Turner Dan; Götte Matthias; Wainberg Mark A
Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase.
Antimicrobial agents and chemotherapy 2005;49(7):2657-64.
2005: Zolopa Andrew R; Lazzeroni Laura C; Rinehart Alex; Vezinet Françoise Brun; Clavel François; Collier Ann; Conway Brian; Gulick Roy M; Holodniy Mark; Perno Carlo-Frederico; Shafer Robert W; Richman Douglas D; Wainberg Mark A; Kuritzkes Daniel R
Accuracy, precision, and consistency of expert HIV type 1 genotype interpretation: an international comparison (The GUESS Study).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41(1):92-9.
2005: Wainberg Mark A; Brenner Bluma G; Turner Dan
Changing patterns in the selection of viral mutations among patients receiving nucleoside and nucleotide drug combinations directed against human immunodeficiency virus type 1 reverse transcriptase.
Antimicrobial agents and chemotherapy 2005;49(5):1671-8.
2005: Roldan Ariel; Warren Otis U; Russell Rodney S; Liang Chen; Wainberg Mark A
A HIV-1 minimal gag protein is superior to nucleocapsid at in vitro annealing and exhibits multimerization-induced inhibition of reverse transcription.
The Journal of biological chemistry 2005;280(17):17488-96.
2005: Wainberg Mark A
Generic HIV drugs--enlightened policy for global health.
The New England journal of medicine 2005;352(8):747-50.
2005: Guo Xiaofeng; Roldan Ariel; Hu Jing; Wainberg Mark A; Liang Chen
Mutation of the SP1 sequence impairs both multimerization and membrane-binding activities of human immunodeficiency virus type 1 Gag.
Journal of virology 2005;79(3):1803-12.
2005: Boulanger Marie-Chloé; Liang Chen; Russell Rodney S; Lin Rongtuan; Bedford Mark T; Wainberg Mark A; Richard Stéphane
Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression.
Journal of virology 2005;79(1):124-31.
2005: Turner Dan; Brenner Bluma; Moisi Daniela; Liang Chen; Wainberg Mark A
Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs.
Journal of the International AIDS Society 2005;7(1):69.
2005: Turner Dan; Brenner Bluma; Mosis Daniela; Liang Chen; Wainberg Mark A
Substitutions in the reverse transcriptase and protease genes of HIV-1 subtype B in untreated individuals and patients treated with antiretroviral drugs.
MedGenMed : Medscape general medicine 2005;7(1):69.
2005: Wainberg Mark A; Sawyer James P C; Montaner Julio S G; Murphy Robert L; Kuritzkes Daniel R; Raffi Francois
Challenges for the clinical development of new nucleoside reverse transcriptase inhibitors for HIV infection.
Antiviral therapy 2005;10(1):13-28.
2004: Turner Dan; Brenner Bluma; Routy Jean-Pierre; Moisi Daniela; Rosberger Zeev; Roger Michel; Wainberg Mark A
Diminished representation of HIV-1 variants containing select drug resistance-conferring mutations in primary HIV-1 infection.
Journal of acquired immune deficiency syndromes (1999) 2004;37(5):1627-31.
2004: Routy Jean-Pierre; Machouf Nimâ; Edwardes Michael D; Brenner Bluma G; Thomas Réjean; Trottier Benoit; Rouleau Danielle; Tremblay Cécile L; Côté Pierre; Baril Jean-Guy; Remis Robert S; Sékaly Rafick P; Wainberg Mark A
Factors associated with a decrease in the prevalence of drug resistance in newly HIV-1 infected individuals in Montreal.
AIDS (London, England) 2004;18(17):2305-12.
2004: Petrella Marco; Oliveira Maureen; Moisi Daniela; Detorio Mervi; Brenner Bluma G; Wainberg Mark A
Differential maintenance of the M184V substitution in the reverse transcriptase of human immunodeficiency virus type 1 by various nucleoside antiretroviral agents in tissue culture.
Antimicrobial agents and chemotherapy 2004;48(11):4189-94.
2004: Doualla-Bell Florence; Turner Dan; Loemba Hugues; Petrella Marco; Brenner Bluma; Wainberg Mark A
[HIV drug resistance and optimization of antiviral treatment in resource-poor countries]
Médecine sciences : M/S 2004;20(10):882-6.
2004: Turner Dan; Roldan Ariel; Brenner Bluma; Moisi Daniela; Routy Jean-Pierre; Wainberg Mark A
Variability in the PR and RT genes of HIV-1 isolated from recently infected subjects.
Antiviral chemistry & chemotherapy 2004;15(5):255-9.
2004: Wainberg Mark A; Turner Dan
Resistance issues with new nucleoside/nucleotide backbone options.
Journal of acquired immune deficiency syndromes (1999) 2004;37 Suppl 1():S36-43.
2004: Roldan Ariel; Russell Rodney S; Marchand Bruno; Götte Matthias; Liang Chen; Wainberg Mark A
In vitro identification and characterization of an early complex linking HIV-1 genomic RNA recognition and Pr55Gag multimerization.
The Journal of biological chemistry 2004;279(38):39886-94.
2004: Brenner Bluma; Routy Jean-Pierre; Quan Yudong; Moisi Daniela; Oliveira Maureen; Turner Dan; Wainberg Mark A;
Persistence of multidrug-resistant HIV-1 in primary infection leading to superinfection.
AIDS (London, England) 2004;18(12):1653-60.
2004: Turner Dan; Brenner Bluma; Moisi Daniela; Detorio Mervi; Cesaire Raymond; Kurimura Takashi; Mori Haruyo; Essex Max; Maayan Shlomo; Wainberg Mark A
Nucleotide and amino acid polymorphisms at drug resistance sites in non-B-subtype variants of human immunodeficiency virus type 1.
Antimicrobial agents and chemotherapy 2004;48(8):2993-8.
2004: Doualla-Bell Florence; Gaseitsiwe Simane; Ndungú Thumbi; Modukanele Musetsanagepe; Peter Trevor; Novitsky Vladimir; Ndwapi Ndwapi; Tendani Gaolathe; Avalos Ava; Wester William; Bussmann Hermann; Cardiello Peter; Marlink Richard; Moffat Howard; Thior Ibou; Wainberg Mark A; Essex Max
Mutations and polymorphisms associated with antiretroviral drugs in HIV-1C-infected African patients.
Antiviral chemistry & chemotherapy 2004;15(4):189-200.
2004: Wainberg Mark A
HIV-1 subtype distribution and the problem of drug resistance.
AIDS (London, England) 2004;18 Suppl 3():S63-8.
2004: Wainberg Mark A
The emergence of HIV resistance and new antiretrovirals: are we winning?
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2004;7(3):163-7.
2004: Turner Dan; Schapiro Jonathan M; Brenner Bluma G; Wainberg Mark A
The influence of protease inhibitor resistance profiles on selection of HIV therapy in treatment-naive patients.
Antiviral therapy 2004;9(3):301-14.
2004: Wainberg Mark A; Brenner Bluma G; Daar Eric; Gertner Joseph M; Olivier Clement; Kenley Susan
Lack of effect of recombinant human growth hormone on the in vitro activities of antiretroviral drugs against human immunodeficiency virus type 1.
Antimicrobial agents and chemotherapy 2004;48(6):2337-40.
2004: Turner D; Brenner B G; Routy J P; Petrella M; Wainberg M A
Rationale for maintenance of the M184v resistance mutation in human immunodeficiency virus type 1 reverse transcriptase in treatment experienced patients.
The new microbiologica : official journal of the Italian Society for Medical, Odontoiatric, and Clinical Microbiology (SIMMOC) 2004;27(2 Suppl 1):31-9.
2004: Wainberg Mark A
The impact of the M184V substitution on drug resistance and viral fitness.
Expert review of anti-infective therapy 2004;2(1):147-51.
2004: Wainberg Mark A
Is there any hope for AIDS?
Clinical and investigative medicine. Médecine clinique et experimentale 2004;27(1):51-8.
2004: Liang Chen; Hu Jing; Russell Rodney S; Kameoka Masanori; Wainberg Mark A
Spliced human immunodeficiency virus type 1 RNA is reverse transcribed into cDNA within infected cells.
AIDS research and human retroviruses 2004;20(2):203-11.
2004: Xie Baode; Calabro Valerie; Wainberg Mark A; Frankel Alan D
Selection of TAR RNA-binding chameleon peptides by using a retroviral replication system.
Journal of virology 2004;78(3):1456-63.
2004: Spira Shalom C; Wainberg Mark A
Jewish religious ethics mandate access to antiretroviral drugs in developing countries.
Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 2004;3(1):7-11.
2004: Turner Dan; Brenner Bluma; Wainberg Mark A
Relationships among various nucleoside resistance-conferring mutations in the reverse transcriptase of HIV-1.
The Journal of antimicrobial chemotherapy 2004;53(1):53-7.
2004: Wainberg Mark A
eJIAS: Editor's Welcome.
MedGenMed : Medscape general medicine 2004;6(3):58.
2004: Russell Rodney S; Liang Chen; Wainberg Mark A
Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably?
Retrovirology 2004;1():23.
2004: Petrella Marco; Montaner Julio; Batist Gerald; Wainberg Mark A
The role of surrogate markers in the clinical development of antiretroviral therapy: a model for early evaluation of targeted cancer drugs.
Cancer investigation 2004;22(1):149-60.
2003: Gallant Joel E; Gerondelis Peter Z; Wainberg Mark A; Shulman Nancy S; Haubrich Richard H; St Clair Marty; Lanier Ernest R; Hellmann Nicholas S; Richman Douglas D
Nucleoside and nucleotide analogue reverse transcriptase inhibitors: a clinical review of antiretroviral resistance.
Antiviral therapy 2003;8(6):489-506.
2003: Russell Rodney S; Roldan Ariel; Detorio Mervi; Hu Jing; Wainberg Mark A; Liang Chen
Effects of a single amino acid substitution within the p2 region of human immunodeficiency virus type 1 on packaging of spliced viral RNA.
Journal of virology 2003;77(24):12986-95.
2003: Turner Dan; Brenner Bluma; Wainberg Mark A
Multiple effects of the M184V resistance mutation in the reverse transcriptase of human immunodeficiency virus type 1.
Clinical and diagnostic laboratory immunology 2003;10(6):979-81.
2003: Diallo Karidia; Götte Matthias; Wainberg M A
Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase.
Antimicrobial agents and chemotherapy 2003;47(11):3377-83.
2003: Quan Yudong; Brenner Bluma G; Marlink Richard G; Essex Max; Kurimura Takashi; Wainberg Mark A
Drug resistance profiles of recombinant reverse transcriptases from human immunodeficiency virus type 1 subtypes A/E, B, and C.
AIDS research and human retroviruses 2003;19(9):743-53.
2003: Wainberg Mark A
HIV resistance to nevirapine and other non-nucleoside reverse transcriptase inhibitors.
Journal of acquired immune deficiency syndromes (1999) 2003;34 Suppl 1():S2-7.
2003: Rong Liwei; Russell Rodney S; Hu Jing; Laughrea Michael; Wainberg Mark A; Liang Chen
Deletion of stem-loop 3 is compensated by second-site mutations within the Gag protein of human immunodeficiency virus type 1.
Virology 2003;314(1):221-8.
2003: Germinario R J; Colby-Germinario S P; Cammalleri C; Wainberg M A
The long-term effects of anti-retroviral protease inhibitors on sugar transport in L6 cells.
The Journal of endocrinology 2003;178(3):449-56.
2003: Diallo Karidia; Marchand Bruno; Wei Xin; Cellai Luciano; Götte Matthias; Wainberg Mark A
Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity.
Journal of virology 2003;77(16):8621-32.
2003: Youle Mike; Wainberg Mark A
Pre-exposure chemoprophylaxis (PREP) as an HIV prevention strategy.
Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 2003;2(3):102-5.
2003: Diallo Karidia; Brenner Bluma; Oliveira Maureen; Moisi Daniela; Detorio Mervi; Götte Matthias; Wainberg Mark A
The M184V substitution in human immunodeficiency virus type 1 reverse transcriptase delays the development of resistance to amprenavir and efavirenz in subtype B and C clinical isolates.
Antimicrobial agents and chemotherapy 2003;47(7):2376-9.
2003: Wei Xin; Liang Chen; Götte Matthias; Wainberg Mark A
Negative effect of the M184V mutation in HIV-1 reverse transcriptase on initiation of viral DNA synthesis.
Virology 2003;311(1):202-12.
2003: Klein Marina B; Campeol Nadia; Lalonde Richard G; Brenner Bluma; Wainberg Mark A
Didanosine, interferon-alfa and ribavirin: a highly synergistic combination with potential activity against HIV-1 and hepatitis C virus.
AIDS (London, England) 2003;17(7):1001-8.
2003: Youle Mike; Wainberg Mark A
Could chemoprophylaxis be used as an HIV prevention strategy while we wait for an effective vaccine?
AIDS (London, England) 2003;17(6):937-8.
2003: Guo Xiaofeng; Kameoka Masanori; Wei Xin; Roques Bernard; Gotte Matthias; Liang Chen; Wainberg Mark A
Suppression of an intrinsic strand transfer activity of HIV-1 Tat protein by its second-exon sequences.
Virology 2003;307(1):154-63.
2003: Spira Shalom; Wainberg Mark A; Loemba Hugues; Turner Dan; Brenner Bluma G
Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance.
The Journal of antimicrobial chemotherapy 2003;51(2):229-40.
2003: Quan Yudong; Brenner Bluma G; Oliveira Maureen; Wainberg Mark A
Lamivudine can exert a modest antiviral effect against human immunodeficiency virus type 1 containing the M184V mutation.
Antimicrobial agents and chemotherapy 2003;47(2):747-54.
2003: Xie Baode; Wainberg Mark A; Frankel Alan D
Replication of human immunodeficiency viruses engineered with heterologous Tat-transactivation response element interactions.
Journal of virology 2003;77(3):1984-91.
2003: Liang Chen; Hu Jing; Whitney James B; Kleiman Lawrence; Wainberg Mark A
A structurally disordered region at the C terminus of capsid plays essential roles in multimerization and membrane binding of the gag protein of human immunodeficiency virus type 1.
Journal of virology 2003;77(3):1772-83.
2003: Brenner Bluma; Turner Dan; Oliveira Maureen; Moisi Daniela; Detorio Mervi; Carobene Mauricio; Marlink Richard G; Schapiro Jonathan; Roger Michel; Wainberg Mark A
A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to non-nucleoside reverse transcriptase inhibitors.
AIDS (London, England) 2003;17(1):F1-5.
2003: Russell Rodney S; Hu Jing; Bériault Véronique; Mouland Andrew J; Laughrea Michael; Kleiman Lawrence; Wainberg Mark A; Liang Chen
Sequences downstream of the 5' splice donor site are required for both packaging and dimerization of human immunodeficiency virus type 1 RNA.
Journal of virology 2003;77(1):84-96.
2002: Wei Xin; Liang Chen; Götte Matthias; Wainberg Mark A
The M184V mutation in HIV-1 reverse transcriptase reduces the restoration of wild-type replication by attenuated viruses.
AIDS (London, England) 2002;16(18):2391-8.
2002: Russell Rodney S; Hu Jing; Laughrea Michael; Wainberg Mark A; Liang Chen
Deficient dimerization of human immunodeficiency virus type 1 RNA caused by mutations of the u5 RNA sequences.
Virology 2002;303(1):152-63.
2002: Hogg Robert; Cahn Pedro; Katabira Elly T; Lange Joep; Samuel N M; O'Shaughnessy Michael; Vella Stefano; Wainberg Mark A; Montaner Julio
Time to act: global apathy towards HIV/AIDS is a crime against humanity.
Lancet 2002;360(9347):1710-1.
2002: Liang Chen; Hu Jing; Russell Rodney S; Roldan Ariel; Kleiman Lawrence; Wainberg Mark A
Characterization of a putative alpha-helix across the capsid-SP1 boundary that is critical for the multimerization of human immunodeficiency virus type 1 gag.
Journal of virology 2002;76(22):11729-37.
2002: Loemba Hugues; Brenner Bluma; Parniak Michael A; Ma'ayan Shlomo; Spira Bonnie; Moisi Daniela; Oliveira Maureen; Detorio Mervi; Essex Max; Wainberg Mark A
Polymorphisms of cytotoxic T-lymphocyte (CTL) and T-helper epitopes within reverse transcriptase (RT) of HIV-1 subtype C from Ethiopia and Botswana following selection of antiretroviral drug resistance.
Antiviral research 2002;56(2):129-42.
2002: Petrella Marco; Wainberg Mark A
Might the M184V substitution in HIV-1 RT confer clinical benefit?
AIDS reviews 2002;4(4):224-32.
2002: Liang Chen; Hu Jing; Russell Rodney S; Wainberg Mark A
Translation of Pr55(gag) augments packaging of human immunodeficiency virus type 1 RNA in a cis-acting manner.
AIDS research and human retroviruses 2002;18(15):1117-26.
2002: Brenner Bluma G; Turner Dan; Wainberg Mark A
HIV-1 drug resistance: can we overcome?
Expert opinion on biological therapy 2002;2(7):751-61.
2002: Whitney James B; Oliveira Maureen; Detorio Mervi; Guan Yongjun; Wainberg Mark A
The M184V mutation in reverse transcriptase can delay reversion of attenuated variants of simian immunodeficiency virus.
Journal of virology 2002;76(17):8958-62.
2002: McLellan N; Wei X; Marchand B; Wainberg M A; Götte M
Nonradioactive detection of retroviral-associated RNase H activity in a microplate-based, high-throughput format.
BioTechniques 2002;33(2):424-9.
2002: Borkow Gadi; Salomon Horacio; Wainberg Mark A; Parniak Michael A
Attenuated infectivity of HIV type 1 from epithelial cells pretreated with a tight-binding nonnucleoside reverse transcriptase inhibitor.
AIDS research and human retroviruses 2002;18(10):711-4.
2002: Diallo Karidia; Oliveira Maureen; Moisi Daniela; Brenner Bluma; Wainberg Mark A; Götte Matthias
Pressure of zidovudine accelerates the reversion of lamivudine resistance-conferring M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1.
Antimicrobial agents and chemotherapy 2002;46(7):2254-6.
2002: Loemba Hugues; Brenner Bluma; Parniak Michael A; Ma'ayan Shlomo; Spira Bonnie; Moisi Daniela; Oliveira Maureen; Detorio Mervi; Wainberg Mark A
Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT.
Antimicrobial agents and chemotherapy 2002;46(7):2087-94.
2002: Loemba Hugues; Brenner Bluma; Parniak Michael A; Ma'ayan Shlomo; Spira Bonnie; Moisi Daniela; Oliveira Maureen; Detorio Mervi; Essex Max; Wainberg Mark A
Co-receptor usage and HIV-1 intra-clade C polymorphisms in the protease and reverse transcriptase genes of HIV-1 isolates from Ethiopia and Botswana.
Antiviral therapy 2002;7(2):141-8.
2002: Van Rompay Koen K A; Matthews Tim B; Higgins Joanne; Canfield Don R; Tarara Ross P; Wainberg Mark A; Schinazi Raymond F; Pedersen Niels C; North Thomas W
Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase.
Journal of virology 2002;76(12):6083-92.
2002: Roof Philippe; Ricci Maria; Genin Pierre; Montano Monty A; Essex Max; Wainberg Mark A; Gatignol Anne; Hiscott John
Differential regulation of HIV-1 clade-specific B, C, and E long terminal repeats by NF-kappaB and the Tat transactivator.
Virology 2002;296(1):77-83.
2002: Khorchid Ahmad; Halwani Rabih; Wainberg Mark A; Kleiman Lawrence
Role of RNA in facilitating Gag/Gag-Pol interaction.
Journal of virology 2002;76(8):4131-7.
2002: Kameoka Masanori; Morgan Max; Binette Marc; Russell Rodney S; Rong Liwei; Guo Xiaofeng; Mouland Andrew; Kleiman Lawrence; Liang Chen; Wainberg Mark A
The Tat protein of human immunodeficiency virus type 1 (HIV-1) can promote placement of tRNA primer onto viral RNA and suppress later DNA polymerization in HIV-1 reverse transcription.
Journal of virology 2002;76(8):3637-45.
2002: Brenner Bluma G; Routy Jean-Pierre; Petrella Marco; Moisi Daniela; Oliveira Maureen; Detorio Mervi; Spira Bonnie; Essabag Vidal; Conway Brian; Lalonde Richard; Sekaly Rafick-Pierre; Wainberg Mark A
Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection.
Journal of virology 2002;76(4):1753-61.
2002: Liang Chen; Wainberg Mark A
The role of Tat in HIV-1 replication: an activator and/or a suppressor?
AIDS reviews 2002;4(1):41-9.
2002: Brulé Fabienne; Marquet Roland; Rong Liwei; Wainberg Mark A; Roques Bernard P; Le Grice Stuart F J; Ehresmann Bernard; Ehresmann Chantal
Structural and functional properties of the HIV-1 RNA-tRNA(Lys)3 primer complex annealed by the nucleocapsid protein: comparison with the heat-annealed complex.
RNA (New York, N.Y.) 2002;8(1):8-15.
2001: Petrella M; Brenner B; Loemba H; Wainberg M A
HIV drug resistance and implications for the introduction of antiretroviral therapy in resource-poor countries.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2001;4(6):339-46.
2001: Guan Y; Diallo K; Whitney J B; Liang C; Wainberg M A
An intact U5-leader stem is important for efficient replication of simian immunodeficiency virus.
Journal of virology 2001;75(23):11924-9.
2001: Guan Y; Diallo K; Detorio M; Whitney J B; Liang C; Wainberg M A
Partial restoration of replication of simian immunodeficiency virus by point mutations in either the dimerization initiation site (DIS) or Gag region after deletion mutagenesis within the DIS.
Journal of virology 2001;75(23):11920-3.
2001: Rong L; Liang C; Hsu M; Guo X; Roques B P; Wainberg M A
HIV-1 nucleocapsid protein and the secondary structure of the binary complex formed between tRNA(Lys.3) and viral RNA template play different roles during initiation of (-) strand DNA reverse transcription.
The Journal of biological chemistry 2001;276(50):47725-32.
2001: Shen N; Jetté L; Wainberg M A; Laughrea M
Role of stem B, loop B, and nucleotides next to the primer binding site and the kissing-loop domain in human immunodeficiency virus type 1 replication and genomic-RNA dimerization.
Journal of virology 2001;75(21):10543-9.
2001: Rong L; Russell R S; Hu J; Guan Y; Kleiman L; Liang C; Wainberg M A
Hydrophobic amino acids in the human immunodeficiency virus type 1 p2 and nucleocapsid proteins can contribute to the rescue of deleted viral RNA packaging signals.
Journal of virology 2001;75(16):7230-43.
2001: Conway B; Wainberg M A; Hall D; Harris M; Reiss P; Cooper D; Vella S; Curry R; Robinson P; Lange J M; Montaner J S
Development of drug resistance in patients receiving combinations of zidovudine, didanosine and nevirapine.
AIDS (London, England) 2001;15(10):1269-74.
2001: Guan Y; Whitney J B; Detorio M; Wainberg M A
Construction and in vitro properties of a series of attenuated simian immunodeficiency viruses with all accessory genes deleted.
Journal of virology 2001;75(9):4056-67.
2001: Guan Y; Whitney J B; Liang C; Wainberg M A
Novel, live attenuated simian immunodeficiency virus constructs containing major deletions in leader RNA sequences.
Journal of virology 2001;75(6):2776-85.
2001: Kameoka M; Rong L; Götte M; Liang C; Russell R S; Wainberg M A
Role for human immunodeficiency virus type 1 Tat protein in suppression of viral reverse transcriptase activity during late stages of viral replication.
Journal of virology 2001;75(6):2675-83.
2001: Laughrea M; Shen N; Jetté L; Darlix J L; Kleiman L; Wainberg M A
Role of distal zinc finger of nucleocapsid protein in genomic RNA dimerization of human immunodeficiency virus type 1; no role for the palindrome crowning the R-U5 hairpin.
Virology 2001;281(1):109-16.
2001: Götte M; Kameoka M; McLellan N; Cellai L; Wainberg M A
Analysis of efficiency and fidelity of HIV-1 (+)-strand DNA synthesis reveals a novel rate-limiting step during retroviral reverse transcription.
The Journal of biological chemistry 2001;276(9):6711-9.
2001: Wainberg M A
Microbicides 2000 conference. Welcoming remarks. The global need for microbicides.
AIDS (London, England) 2001;15 Suppl 1():S1-2.
2001: Wainberg M A; White A J
Current insights into reverse transcriptase inhibitor-associated resistance.
Antiviral therapy 2001;6 Suppl 2():11-9.
2000: Brenner B; Wainberg M A; Salomon H; Rouleau D; Dascal A; Spira B; Sekaly R P; Conway B; Routy J P
Resistance to antiretroviral drugs in patients with primary HIV-1 infection. Investigators of the Quebec Primary Infection Study.
International journal of antimicrobial agents 2000;16(4):429-34.
2000: Richard N; Salomon H; Oliveira M; Rando R; Mansour T; Gu Z; Wainberg M A
Selection of resistance-conferring mutations in HIV-1 by the nucleoside reverse transcriptase inhibitors (+/-)dOTC and (+/-)dOTFC.
Antiviral chemistry & chemotherapy 2000;11(6):359-65.
2000: Brenner B G; Wainberg M A
The role of antiretrovirals and drug resistance in vertical transmission of HIV-1 infection.
Annals of the New York Academy of Sciences 2000;918():9-15.
2000: Cen S; Khorchid A; Gabor J; Rong L; Wainberg M A; Kleiman L
Roles of Pr55(gag) and NCp7 in tRNA(3)(Lys) genomic placement and the initiation step of reverse transcription in human immunodeficiency virus type 1.
Journal of virology 2000;74(22):10796-800.
2000: Guan Y; Whitney J B; Diallo K; Wainberg M A
Leader sequences downstream of the primer binding site are important for efficient replication of simian immunodeficiency virus.
Journal of virology 2000;74(19):8854-60.
2000: Wei X; Götte M; Wainberg M A
Human immunodeficiency virus type-1 reverse transcription can be inhibited in vitro by oligonucleotides that target both natural and synthetic tRNA primers.
Nucleic acids research 2000;28(16):3065-74.
2000: Liang C; Rong L; Russell R S; Wainberg M A
Deletion mutagenesis downstream of the 5' long terminal repeat of human immunodeficiency virus type 1 is compensated for by point mutations in both the U5 region and gag gene.
Journal of virology 2000;74(14):6251-61.
2000: Shen N; Jetté L; Liang C; Wainberg M A; Laughrea M
Impact of human immunodeficiency virus type 1 RNA dimerization on viral infectivity and of stem-loop B on RNA dimerization and reverse transcription and dissociation of dimerization from packaging.
Journal of virology 2000;74(12):5729-35.
2000: Khorchid A; Javanbakht H; Wise S; Halwani R; Parniak M A; Wainberg M A; Kleiman L
Sequences within Pr160gag-pol affecting the selective packaging of primer tRNA(Lys3) into HIV-1.
Journal of molecular biology 2000;299(1):17-26.
2000: Richard N; Salomon H; Rando R; Mansour T; Bowlin T L; Wainberg M A
Selection and characterization of human immunodeficiency virus type 1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thio-5-fluorocytidine.
Antimicrobial agents and chemotherapy 2000;44(5):1127-31.
2000: Hsu M; Rong L; de Rocquigny H; Roques B P; Wainberg M A
The effect of mutations in the HIV-1 nucleocapsid protein on strand transfer in cell-free reverse transcription reactions.
Nucleic acids research 2000;28(8):1724-9.
2000: Götte M; Arion D; Parniak M A; Wainberg M A
The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis.
Journal of virology 2000;74(8):3579-85.
2000: Hsu M; Wainberg M A
Interactions between human immunodeficiency virus type 1 reverse transcriptase, tRNA primer, and nucleocapsid protein during reverse transcription.
Journal of human virology 2000;3(1):16-26.
2000: Salomon H; Wainberg M A; Brenner B; Quan Y; Rouleau D; Coté P; LeBlanc R; Lefebvre E; Spira B; Tsoukas C; Sekaly R P; Conway B; Mayers D; Routy J P
Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use. Investigators of the Quebec Primary Infection Study.
AIDS (London, England) 2000;14(2):F17-23.
1999: Gu Z; Wainberg M A; Nguyen-Ba N; L'Heureux L; de Muys J M; Bowlin T L; Rando R F
Mechanism of action and in vitro activity of 1',3'-dioxolanylpurine nucleoside analogues against sensitive and drug-resistant human immunodeficiency virus type 1 variants.
Antimicrobial agents and chemotherapy 1999;43(10):2376-82.
1999: DeLuca C; Kwon H; Lin R; Wainberg M; Hiscott J
NF-kappaB activation and HIV-1 induced apoptosis.
Cytokine & growth factor reviews 1999;10(3-4):235-53.
1999: Génin P; Mamane Y; Kwon H; LePage C; Wainberg M A; Hiscott J
Differential regulation of CC chemokine gene expression in human immunodeficiency virus-infected myeloid cells.
Virology 1999;261(2):205-15.
1999: de Muys J M; Gourdeau H; Nguyen-Ba N; Taylor D L; Ahmed P S; Mansour T; Locas C; Richard N; Wainberg M A; Rando R F
Anti-human immunodeficiency virus type 1 activity, intracellular metabolism, and pharmacokinetic evaluation of 2'-deoxy-3'-oxa-4'-thiocytidine.
Antimicrobial agents and chemotherapy 1999;43(8):1835-44.
1999: Liang C; Rong L; Quan Y; Laughrea M; Kleiman L; Wainberg M A
Mutations within four distinct gag proteins are required to restore replication of human immunodeficiency virus type 1 after deletion mutagenesis within the dimerization initiation site.
Journal of virology 1999;73(8):7014-20.
1999: Quan Y; Rong L; Liang C; Wainberg M A
Reverse transcriptase inhibitors can selectively block the synthesis of differently sized viral DNA transcripts in cells acutely infected with human immunodeficiency virus type 1.
Journal of virology 1999;73(8):6700-7.
1999: Wainberg M A; Kallings L O
The International Conference on AIDS. Why we chose South Africa.
AIDS (London, England) 1999;13(11):11-2.
1999: Liang C; Rong L; Cherry E; Kleiman L; Laughrea M; Wainberg M A
Deletion mutagenesis within the dimerization initiation site of human immunodeficiency virus type 1 results in delayed processing of the p2 peptide from precursor proteins.
Journal of virology 1999;73(7):6147-51.
1999: Germinario R J; Colby-Germinario S P; Acel A; Chandok R; Davison K; Mak J; Kleiman L; Faust E; Wainberg M A
Effect of insulin-like growth factor I on HIV type 1 long terminal repeat-driven chloramphenicol acetyltransferase expression.
AIDS research and human retroviruses 1999;15(9):829-36.
1999: Wainberg M A
A new source of resistance to HIV drugs.
JAMA : the journal of the American Medical Association 1999;281(23):2169-70.
1999: Götte M; Li X; Wainberg M A
HIV-1 reverse transcription: a brief overview focused on structure-function relationships among molecules involved in initiation of the reaction.
Archives of biochemistry and biophysics 1999;365(2):199-210.
1999: Cen S; Huang Y; Khorchid A; Darlix J L; Wainberg M A; Kleiman L
The role of Pr55(gag) in the annealing of tRNA3Lys to human immunodeficiency virus type 1 genomic RNA.
Journal of virology 1999;73(5):4485-8.
1999: Machado J; Salomon H; Oliveira M; Tsoukas C; Krayevsky A A; Wainberg M A
Antiviral activity and resistance profile of phosphazid--a novel prodrug of AZT.
Nucleosides & nucleotides 1999;18(4-5):901-6.
1999: Gu Z; Wainberg M A; Nguyen-Ba P; L'Heureux L; de Muys J M; Rando R F
Anti-HIV-1 activities of 1,3-dioxolane guanine and 2,6-diaminopurine dioxolane.
Nucleosides & nucleotides 1999;18(4-5):891-2.
1999: Richard N; Salomon H; Oliveira M; Rando R; Wainberg M A
Resistance profiles of (+)2'-deoxy-3'-oxa-4'-thiocytidine and (-)2'-deoxy-3'-oxa-4'-thio-5-fluorocytidine.
Nucleosides & nucleotides 1999;18(4-5):773-8.
1999: Hsu M; Cherry E; Quan Y; Richard N; Kleiman L; Wainberg M A
Effect of mutations in NC7 on endogenous reverse transcription in HIV-1.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13 Suppl 1():S113-5.
1999: Götte M; Maier G; Onori A M; Cellai L; Wainberg M A; Heumann H
Temporal coordination between initiation of HIV (+)-strand DNA synthesis and primer removal.
The Journal of biological chemistry 1999;274(16):11159-69.
1999: Wainberg M A
The need for microbicides: why aren't women's groups more involved in the fight against AIDS?
AIDS research and human retroviruses 1999;15(5):405-6.
1999: Borkow G; Arion D; Wainberg M A; Parniak M A
The thiocarboxanilide nonnucleoside inhibitor UC781 restores antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus type 1.
Antimicrobial agents and chemotherapy 1999;43(2):259-63.
1999: Laughrea M; Shen N; Jetté L; Wainberg M A
Variant effects of non-native kissing-loop hairpin palindromes on HIV replication and HIV RNA dimerization: role of stem-loop B in HIV replication and HIV RNA dimerization.
Biochemistry 1999;38(1):226-34.
1999: Richar N; Quan Y; Salomon H; Hsu M; Bedard J; Harrigan P R; Rando R; Mansour T; Bowlin T L; Wainberg M A
Selection and characterization of HIV-1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thiocytidine (dOTC).
Antiviral therapy 1999;4(3):171-7.
1999: Quan Y; Motakis D; Buckheit R; Xu Z Q; Flavin M T; Parniak M A; Wainberg M A
Sensitivity and resistance to (+)-calanolide A of wild-type and mutated forms of HIV-1 reverse transcriptase.
Antiviral therapy 1999;4(4):203-9.
1999: Wainberg M A; Miller M D; Quan Y; Salomon H; Mulato A S; Lamy P D; Margot N A; Anton K E; Cherrington J M
In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA.
Antiviral therapy 1999;4(2):87-94.
1999: Brenner B G; Wainberg M A
Heat shock protein-based therapeutic strategies against human immunodeficiency virus type 1 infection.
Infectious diseases in obstetrics and gynecology 1999;7(1-2):80-90.
1998: Quan Y; Liang C; Inouye P; Wainberg M A
Enhanced impairment of chain elongation by inhibitors of HIV reverse transcriptase in cell-free reactions yielding longer DNA products.
Nucleic acids research 1998;26(24):5692-8.
1998: Rae S; Raboud J M; Conway B; Reiss P; Vella S; Cooper D; Lange J; Harris M; Wainberg M A; Robinson P; Myers M; Hall D; Montaner J S
Estimates of the virological benefit of antiretroviral therapy are both assay- and analysis-dependent.
AIDS (London, England) 1998;12(16):2185-92.
1998: Cherry E; Liang C; Rong L; Quan Y; Inouye P; Li X; Morin N; Kotler M; Wainberg M A
Characterization of human immunodeficiency virus type-1 (HIV-1) particles that express protease-reverse transcriptase fusion proteins.
Journal of molecular biology 1998;284(1):43-56.
1998: Rong L; Liang C; Hsu M; Kleiman L; Petitjean P; de Rocquigny H; Roques B P; Wainberg M A
Roles of the human immunodeficiency virus type 1 nucleocapsid protein in annealing and initiation versus elongation in reverse transcription of viral negative-strand strong-stop DNA.
Journal of virology 1998;72(11):9353-8.
1998: Caro C; Colby-Germinario S; Brenner B; Oliveira M; Wainberg M A; Germinario R J
Sugar transport and glut transporter expression in a variety of human immunodeficiency virus-1 (HIV-1) chronically infected target cell lines.
The international journal of biochemistry & cell biology 1998;30(9):1031-8.
1998: Raboud J M; Montaner J S; Conway B; Rae S; Reiss P; Vella S; Cooper D; Lange J; Harris M; Wainberg M A; Robinson P; Myers M; Hall D
Suppression of plasma viral load below 20 copies/ml is required to achieve a long-term response to therapy.
AIDS (London, England) 1998;12(13):1619-24.
1998: Drosopoulos W C; Rezende L F; Wainberg M A; Prasad V R
Virtues of being faithful: can we limit the genetic variation in human immunodeficiency virus?
Journal of molecular medicine (Berlin, Germany) 1998;76(9):604-12.
1998: Quan Y; Inouye P; Liang C; Rong L; Götte M; Wainberg M A
Dominance of the E89G substitution in HIV-1 reverse transcriptase in regard to increased polymerase processivity and patterns of pausing.
The Journal of biological chemistry 1998;273(34):21918-25.
1998: Liang C; Rong L; Götte M; Li X; Quan Y; Kleiman L; Wainberg M A
Mechanistic studies of early pausing events during initiation of HIV-1 reverse transcription.
The Journal of biological chemistry 1998;273(33):21309-15.
1998: Liang C; Rong L; Laughrea M; Kleiman L; Wainberg M A
Compensatory point mutations in the human immunodeficiency virus type 1 Gag region that are distal from deletion mutations in the dimerization initiation site can restore viral replication.
Journal of virology 1998;72(8):6629-36.
1998: Cherry E; Morin N; Wainberg M A
Effect of HIV constructs containing protease-reverse transcriptase fusion proteins on viral replication.
AIDS (London, England) 1998;12(9):967-75.
1998: Wainberg M A; Friedland G
Public health implications of antiretroviral therapy and HIV drug resistance.
JAMA : the journal of the American Medical Association 1998;279(24):1977-83.
1998: Inouye P; Cherry E; Hsu M; Zolla-Pazner S; Wainberg M A
Neutralizing antibodies directed against the V3 loop select for different escape variants in a virus with mutated reverse transcriptase (M184V) than in wild-type human immunodeficiency virus type 1.
AIDS research and human retroviruses 1998;14(9):735-40.
1998: Mayers D; Bethel J; Wainberg M A; Weislow O; Schnittman S
Human immunodeficiency virus proviral DNA from peripheral blood and lymph nodes demonstrates concordant resistance mutations to zidovudine (codon 215) and didanosine (codon 74). Division of AIDS Treatment Research Initiative 003 Study Group.
The Journal of infectious diseases 1998;177(6):1730-3.
1998: Huang Y; Khorchid A; Gabor J; Wang J; Li X; Darlix J L; Wainberg M A; Kleiman L
The role of nucleocapsid and U5 stem/A-rich loop sequences in tRNA(3Lys) genomic placement and initiation of reverse transcription in human immunodeficiency virus type 1.
Journal of virology 1998;72(5):3907-15.
1998: DeLuca C; Kwon H; Pelletier N; Wainberg M A; Hiscott J
NF-kappaB protects HIV-1-infected myeloid cells from apoptosis.
Virology 1998;244(1):27-38.
1998: Tsoukas C M; Raboud J; Bernard N F; Montaner J S; Gill M J; Rachlis A; Fong I W; Schlech W; Djurdjev O; Freedman J; Thomas R; Lafrenière R; Wainberg M A; Cassol S; O'Shaughnessy M; Todd J; Volvovitz F; Smith G E
Active immunization of patients with HIV infection: a study of the effect of VaxSyn, a recombinant HIV envelope subunit vaccine, on progression of immunodeficiency.
AIDS research and human retroviruses 1998;14(6):483-90.
1998: Morin N; Cherry E; Li X; Wainberg M A
Cotransfection of mutated forms of human immunodeficiency virus type 1 Gag-Pol with wild-type constructs can interfere with processing and viral replication.
Journal of human virology 1998;1(3):240-7.
1998: Kwon H; Pelletier N; DeLuca C; Genin P; Cisternas S; Lin R; Wainberg M A; Hiscott J
Inducible expression of IkappaBalpha repressor mutants interferes with NF-kappaB activity and HIV-1 replication in Jurkat T cells.
The Journal of biological chemistry 1998;273(13):7431-40.
1998: Quan Y; Gu Z; Li X; Liang C; Parniak M A; Wainberg M A
Endogenous reverse transcriptase assays reveal synergy between combinations of the M184V and other drug resistance-conferring mutations in interactions with nucleoside analog triphosphates.
Journal of molecular biology 1998;277(2):237-47.
1998: Acel A; Udashkin B E; Wainberg M A; Faust E A
Efficient gap repair catalyzed in vitro by an intrinsic DNA polymerase activity of human immunodeficiency virus type 1 integrase.
Journal of virology 1998;72(3):2062-71.
1998: Wainberg M A; Cameron D W
HIV resistance to antiviral drugs: public health implications.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 1998;1(2):104-8.
1998: Salomon H; Montaner J S; Belmonte A; Wainberg M A
Diminished HIV-1 sensitivity to stavudine in patients on prolonged therapy occurs only at low levels and cannot be attributed to any single amino acid substitution in reverse transcriptase.
Antiviral therapy 1998;3(3):177-82.
1997: Cherry E; Slater M; Salomon H; Rud E; Wainberg M A
Mutations at codon 184 in simian immunodeficiency virus reverse transcriptase confer resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine.
Antimicrobial agents and chemotherapy 1997;41(12):2763-5.
1997: Liang C; Rong L; Morin N; Cherry E; Huang Y; Kleiman L; Wainberg M A
The roles of the human immunodeficiency virus type 1 Pol protein and the primer binding site in the placement of primer tRNA(3Lys) onto viral genomic RNA.
Journal of virology 1997;71(12):9075-86.
1997: Bour S; Geleziunas R; Wainberg M A
Inhibition of CD4 translation mediated by human immunodeficiency virus type 1 envelope protein in a cell-free system.
The Journal of biological chemistry 1997;272(46):29005-14.
1997: Hsu M; Inouye P; Rezende L; Richard N; Li Z; Prasad V R; Wainberg M A
Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1.
Nucleic acids research 1997;25(22):4532-6.
1997: Liang C; Li X; Quan Y; Laughrea M; Kleiman L; Hiscott J; Wainberg M A
Sequence elements downstream of the human immunodeficiency virus type 1 long terminal repeat are required for efficient viral gene transcription.
Journal of molecular biology 1997;272(2):167-77.
1997: Li X; Liang C; Quan Y; Chandok R; Laughrea M; Parniak M A; Kleiman L; Wainberg M A
Identification of sequences downstream of the primer binding site that are important for efficient replication of human immunodeficiency virus type 1.
Journal of virology 1997;71(8):6003-10.
1997: Liang C; Li X; Rong L; Inouye P; Quan Y; Kleiman L; Wainberg M A
The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.
Journal of virology 1997;71(8):5750-7.
1997: Huang Y; Khorchid A; Wang J; Parniak M A; Darlix J L; Wainberg M A; Kleiman L
Effect of mutations in the nucleocapsid protein (NCp7) upon Pr160(gag-pol) and tRNA(Lys) incorporation into human immunodeficiency virus type 1.
Journal of virology 1997;71(6):4378-84.
1997: Li X; Quan Y; Wainberg M A
Controlling elements in replication of the human immunodeficiency virus type 1.
Cellular and molecular biology (Noisy-le-Grand, France) 1997;43(3):443-54.
1997: Laughrea M; Jetté L; Mak J; Kleiman L; Liang C; Wainberg M A
Mutations in the kissing-loop hairpin of human immunodeficiency virus type 1 reduce viral infectivity as well as genomic RNA packaging and dimerization.
Journal of virology 1997;71(5):3397-406.
1997: Wainberg M A
Increased fidelity of drug-selected M184V mutated HIV-1 reverse transcriptase as the basis for the effectiveness of 3TC in HIV clinical trials.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11 Suppl 3():85-8.
1997: Borkow G; Barnard J; Nguyen T M; Belmonte A; Wainberg M A; Parniak M A
Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase.
Journal of virology 1997;71(4):3023-30.
1997: Nagai K; Wong A H; Li S; Tam W N; Cuddihy A R; Sonenberg N; Mathews M B; Hiscott J; Wainberg M A; Koromilas A E
Induction of CD4 expression and human immunodeficiency virus type 1 replication by mutants of the interferon-inducible protein kinase PKR.
Journal of virology 1997;71(2):1718-25.
1997: Mak J; Khorchid A; Cao Q; Huang Y; Lowy I; Parniak M A; Prasad V R; Wainberg M A; Kleiman L
Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1.
Journal of molecular biology 1997;265(4):419-31.
1997: Huang Y; Wang J; Shalom A; Li Z; Khorchid A; Wainberg M A; Kleiman L
Primer tRNA3Lys on the viral genome exists in unextended and two-base extended forms within mature human immunodeficiency virus type 1.
Journal of virology 1997;71(1):726-8.
1996: Wainberg M A; Hsu M; Gu Z; Borkow G; Parniak M A
Effectiveness of 3TC in HIV clinical trials may be due in part to the M184V substitution in 3TC-resistant HIV-1 reverse transcriptase.
AIDS (London, England) 1996;10 Suppl 5():S3-10.
1996: Foli A; Sogocio K M; Anderson B; Kavlick M; Saville M W; Wainberg M A; Gu Z; Cherrington J M; Mitsuya H; Yarchoan R
In vitro selection and molecular characterization of human immunodeficiency virus type 1 with reduced sensitivity to 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).
Antiviral research 1996;32(2):91-8.
1996: Li Z; Shalom A; Huang Y; Mak J; Arts E; Wainberg M A; Kleiman L
Multiple forms of tRNA(Lys3) in HIV-1.
Biochemical and biophysical research communications 1996;227(2):530-40.
1996: Arts E J; Stetor S R; Li X; Rausch J W; Howard K J; Ehresmann B; North T W; Wöhrl B M; Goody R S; Wainberg M A; Grice S F
Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs: implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10063-8.
1996: Beauparlant P; Kwon H; Clarke M; Lin R; Sonenberg N; Wainberg M; Hiscott J
Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication.
Journal of virology 1996;70(9):5777-85.
1996: Arion D; Harada R; Li X; Wainberg M A; Parniak M A
HIV-1 reverse transcriptase shows no specificity for the binding of primer tRNA(Lys3).
Biochemical and biophysical research communications 1996;225(3):839-43.
1996: Quan Y; Gu Z; Li X; Li Z; Morrow C D; Wainberg M A
Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2'-dideoxy-3'-thiacytidine by mutated M184V human immunodeficiency virus type 1.
Journal of virology 1996;70(8):5642-5.
1996: DeLuca C; Roulston A; Koromilas A; Wainberg M A; Hiscott J
Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-kappaB/Rel pathway via enhanced IkappaBalpha degradation.
Journal of virology 1996;70(8):5183-93.
1996: Li X; Quan Y; Arts E J; Li Z; Preston B D; de Rocquigny H; Roques B P; Darlix J L; Kleiman L; Parniak M A; Wainberg M A
Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site.
Journal of virology 1996;70(8):4996-5004.
1996: Arion D; Borkow G; Gu Z; Wainberg M A; Parniak M A
The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase.
The Journal of biological chemistry 1996;271(33):19860-4.
1996: Kew Y; Salomon H; Olsen L R; Wainberg M A; Prasad V R
The nucleoside analog-resistant E89G mutant of human immunodeficiency virus type 1 reverse transcriptase displays a broader cross-resistance that extends to nonnucleoside inhibitors.
Antimicrobial agents and chemotherapy 1996;40(7):1711-4.
1996: Huang Y; Shalom A; Li Z; Wang J; Mak J; Wainberg M A; Kleiman L
Effects of modifying the tRNA(3Lys) anticodon on the initiation of human immunodeficiency virus type 1 reverse transcription.
Journal of virology 1996;70(7):4700-6.
1996: Wainberg M A; Lewis L; Salomon H; Gu Z; Keller A; Cammack N; Goldsmith J; Church J; Spira B; Wheeler S; Pizzo P
Resistance to (-)-2',3'-dideoxy-3'-thiacytidine (3TC) in HIV-1 isolated from paediatric patients.
Antiviral therapy 1996;1(2):98-104.
1996: Gu Z; Li X; Quan Y; Parniak M A; Wainberg M A
Studies of neutralizing monoclonal antibody to human immunodeficiency virus type 1 reverse transcriptase: antagonistic and synergistic effects in reactions performed in the presence of nucleoside and nonnucleoside inhibitors, respectively.
Journal of virology 1996;70(4):2620-6.
1996: Mercure L; Tannenbaum G S; Schipper H M; Phaneuf D; Wainberg M A
Expression of the somatostatin gene in human astrocytoma cell lines.
Clinical and diagnostic laboratory immunology 1996;3(2):151-5.
1996: Arts E J; Wainberg M A
Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcription.
Antimicrobial agents and chemotherapy 1996;40(3):527-40.
1996: Wainberg M A; Drosopoulos W C; Salomon H; Hsu M; Borkow G; Parniak M; Gu Z; Song Q; Manne J; Islam S; Castriota G; Prasad V R
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase.
Science (New York, N.Y.) 1996;271(5253):1282-5.
1996: Fletcher R S; Holleschak G; Nagy E; Arion D; Borkow G; Gu Z; Wainberg M A; Parniak M A
Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase.
Protein expression and purification 1996;7(1):27-32.
1996: Arts E J; Marois J P; Gu Z; Le Grice S F; Wainberg M A
Effects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNA.
Journal of virology 1996;70(2):712-20.
1996: Arts E J; Wainberg M A
Human immunodeficiency virus type 1 reverse transcriptase and early events in reverse transcription.
Advances in virus research 1996;46():97-163.
1995: Gu Z; Quan Y; Li Z; Arts E J; Wainberg M A
Effects of non-nucleoside inhibitors of human immunodeficiency virus type 1 in cell-free recombinant reverse transcriptase assays.
The Journal of biological chemistry 1995;270(52):31046-51.
1995: Salomon H E; Pampuro S E; Gu Z; Montaner J S; Libonatti O; Wainberg M A
[Basic and clinical aspects of drug resistance in human immunodeficiency virus type 1 infection]
Revista Argentina de microbiología 1995;27(4):214-29.
1995: Montaner J S; Schechter M T; Rachlis A; Gill J; Beaulieu R; Tsoukas C; Raboud J; Cameron B; Salomon H; Dunkle L; Smaldone L; Wainberg M A
Didanosine compared with continued zidovudine therapy for HIV-infected patients with 200 to 500 CD4 cells/mm3. A double-blind, randomized, controlled trial. Canadian HIV Trials Network Protocol 002 Study Group.
Annals of internal medicine 1995;123(8):561-71.
1995: Gu Z; Gao Q; Faust E A; Wainberg M A
Possible involvement of cell fusion and viral recombination in generation of human immunodeficiency virus variants that display dual resistance to AZT and 3TC.
The Journal of general virology 1995;76 ( Pt 10)():2601-5.
1995: Roulston A; Lin R; Beauparlant P; Wainberg M A; Hiscott J
Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors.
Microbiological reviews 1995;59(3):481-505.
1995: Fletcher R S; Arion D; Borkow G; Wainberg M A; Dmitrienko G I; Parniak M A
Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide nonnucleoside compounds.
Biochemistry 1995;34(32):10106-12.
1995: Gu Z; Salomon H; Cherrington J M; Mulato A S; Chen M S; Yarchoan R; Foli A; Sogocio K M; Wainberg M A
K65R mutation of human immunodeficiency virus type 1 reverse transcriptase encodes cross-resistance to 9-(2-phosphonylmethoxyethyl)adenine.
Antimicrobial agents and chemotherapy 1995;39(8):1888-91.
1995: Faust E A; Acel A; Udashkin B; Wainberg M A
Human immunodeficiency virus type 1 integrase stabilizes a linearized HIV-1 LTR plasmid in vivo.
Biochemistry and molecular biology international 1995;36(4):745-58.
1995: Wainberg M A; Gu Z
Targeting HIV reverse transcriptase in novel ways.
Nature medicine 1995;1(7):628-9.
1995: Germinario R J; DeSantis T; Wainberg M A
Insulin-like growth factor 1 and insulin inhibit HIV type 1 replication in cultured cells.
AIDS research and human retroviruses 1995;11(5):555-61.
1995: Wainberg M A; Salomon H; Gu Z; Montaner J S; Cooley T P; McCaffrey R; Ruedy J; Hirst H M; Cammack N; Cameron J
Development of HIV-1 resistance to (-)2'-deoxy-3'-thiacytidine in patients with AIDS or advanced AIDS-related complex.
AIDS (London, England) 1995;9(4):351-7.
1995: Bour S; Geleziunas R; Wainberg M A
The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.
Microbiological reviews 1995;59(1):63-93.
1995: Mercure L; Phaneuf D; Wainberg M A
Differential effect of the immunomodulatory hormone somatostatin on replication of human immunodeficiency virus type 1 in CD4+ and CD8+ T lymphocytes.
Clinical and diagnostic laboratory immunology 1995;2(2):192-8.
1995: Wainberg M A; Gu Z; Salomon H; Arts E J; Kleiman L; Parniak M A; Morin N
[Molecular basis and clinical significance of HIV-1 resistance to nucleoside compounds]
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1995;318(3):315-28.
1995: Gu Z; Arts E J; Parniak M A; Wainberg M A
Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2760-4.
1995: Mansour T S; Jin H; Wang W; Hooker E U; Ashman C; Cammack N; Salomon H; Belmonte A R; Wainberg M A
Anti-human immunodeficiency virus and anti-hepatitis-B virus activities and toxicities of the enantiomers of 2'-deoxy-3'-oxa-4'-thiocytidine and their 5-fluoro analogues in vitro.
Journal of medicinal chemistry 1995;38(1):1-4.
1994: Huang Y; Mak J; Cao Q; Li Z; Wainberg M A; Kleiman L
Incorporation of excess wild-type and mutant tRNA(3Lys) into human immunodeficiency virus type 1.
Journal of virology 1994;68(12):7676-83.
1994: Gu Z; Fletcher R S; Arts E J; Wainberg M A; Parniak M A
The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro.
The Journal of biological chemistry 1994;269(45):28118-22.
1994: Li X; Mak J; Arts E J; Gu Z; Kleiman L; Wainberg M A; Parniak M A
Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replication.
Journal of virology 1994;68(10):6198-206.
1994: Brenner B G; Gornitsky M; Wainberg M A
Interleukin-2-inducible natural immune (lymphokine-activated killer cell) responses as a functional correlate of progression to AIDS.
Clinical and diagnostic laboratory immunology 1994;1(5):538-44.
1994: Bour S; Geleziunas R; Wainberg M A
The role of CD4 and its downmodulation in establishment and maintenance of HIV-1 infection.
Immunological reviews 1994;140():147-71.
1994: Salomon H; Belmonte A; Nguyen K; Gu Z; Gelfand M; Wainberg M A
Comparison of cord blood and peripheral blood mononuclear cells as targets for viral isolation and drug sensitivity studies involving human immunodeficiency virus type 1.
Journal of clinical microbiology 1994;32(8):2000-2.
1994: Mercure L; Lalonde R; Phaneuf D; Brenner B; Wainberg M A
Inhibitory effect of 3'-azido-3'-deoxythymidine on proliferative responsiveness of CD8+ lymphocytes to interleukin-2.
Clinical and diagnostic laboratory immunology 1994;1(4):482-5.
1994: Arts E J; Mak J; Kleiman L; Wainberg M A
DNA found in human immunodeficiency virus type 1 particles may not be required for infectivity.
The Journal of general virology 1994;75 ( Pt 7)():1605-13.
1994: Geleziunas R; Bour S; Wainberg M A
Cell surface down-modulation of CD4 after infection by HIV-1.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(9):593-600.
1994: Smith M; Salomon H; Wainberg M A
Development and significance of nucleoside drug resistance in infection caused by the human immunodeficiency virus type 1.
Clinical and investigative medicine. Médecine clinique et experimentale 1994;17(3):226-43.
1994: Geleziunas R; Bour S; Wainberg M A
HIV-1 associated down-modulation of CD4 gene expression is differentially restricted in lymphocytic and monocytic cell lines.
Journal of leukocyte biology 1994;55(5):589-95.
1994: Mercure L; Brenner B J; Phaneuf D; Tsoukas C; Wainberg M A
Effect of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine on establishment of human immunodeficiency virus type 1 infection in cultured CD8+ lymphocytes.
Antimicrobial agents and chemotherapy 1994;38(5):986-90.
1994: Arts E J; Wainberg M A
Preferential incorporation of nucleoside analogs after template switching during human immunodeficiency virus reverse transcription.
Antimicrobial agents and chemotherapy 1994;38(5):1008-16.
1994: Arts E J; Li X; Gu Z; Kleiman L; Parniak M A; Wainberg M A
Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction.
The Journal of biological chemistry 1994;269(20):14672-80.
1994: Brenner B G; Vo C; Wainberg M A
Different effects of breast cancer, HIV-1 infection and chemotherapy on inducible natural immunity.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8 Suppl 1():S183-5.
1994: Roulston A; Conti L; McKiel V; Wainberg M A; Hiscott J
Virus induction of NF-kappa B/Rel proteins and type I interferon gene expression in myelomonoblastic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8 Suppl 1():S170-4.
1994: Geleziunas R; Bour S; Wainberg M A
Correlation between high level gp160 expression and reduced CD4 biosynthesis in clonal derivatives of human immunodeficiency virus type 1-infected U-937 cells.
The Journal of general virology 1994;75 ( Pt 4)():857-65.
1994: Arts E J; Mak J; Kleiman L; Wainberg M A
Mature reverse transcriptase (p66/p51) is responsible for low levels of viral DNA found in human immunodeficiency virus type 1 (HIV-1).
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8 Suppl 1():S175-8.
1994: Gu Z; Gao Q; Fang H; Parniak M A; Brenner B G; Wainberg M A
Identification of novel mutations that confer drug resistance in the human immunodeficiency virus polymerase gene.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8 Suppl 1():S166-9.
1994: Mak J; Jiang M; Wainberg M A; Hammarskjöld M L; Rekosh D; Kleiman L
Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles.
Journal of virology 1994;68(4):2065-72.
1994: Mercure L; Wainberg M A
Direct involvement of extracellular HIV-1 virions in the apoptosis of CD8+ lymphocytes: a two-step model.
Medical hypotheses 1994;42(3):159-68.
1994: Tremblay M; Meloche S; Gratton S; Wainberg M A; Sékaly R P
Association of p56lck with the cytoplasmic domain of CD4 modulates HIV-1 expression.
The EMBO journal 1994;13(4):774-83.
1994: Gu Z; Gao Q; Fang H; Salomon H; Parniak M A; Goldberg E; Cameron J; Wainberg M A
Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
Antimicrobial agents and chemotherapy 1994;38(2):275-81.
1994: Gao Q; Gu Z; Salomon H; Nagai K; Parniak M A; Wainberg M A
Generation of multiple drug resistance by sequential in vitro passage of the human immunodeficiency virus type 1.
Archives of virology 1994;136(1-2):111-22.
1994: Geleziunas R; Bour S; Wainberg M A
Human immunodeficiency virus type 1-associated CD4 downmodulation.
Advances in virus research 1994;44():203-66.
1993: Mercure L; Phaneuf D; Wainberg M A
Detection of unintegrated human immunodeficiency virus type 1 DNA in persistently infected CD8+ cells.
The Journal of general virology 1993;74 ( Pt 10)():2077-83.
1993: St Luce S; Arts E; Geleziunas R; Bour S; Wainberg M A
Infection of human monocyte-derived macrophages by human immunodeficiency virus mediated by cell-to-cell transmission.
Journal of medical virology 1993;41(1):71-8.
1993: Li X; Gu Z; Geleziunas R; Kleiman L; Wainberg M A; Parniak M A
Expression, purification, and RNA-binding properties of HIV-1 p15gag nucleocapsid protein.
Protein expression and purification 1993;4(4):304-11.
1993: Brenner B G; Gryllis C; Gornitsky M; Wainberg M A
Changes in natural immunity during the course of HIV-1 infection.
Clinical and experimental immunology 1993;93(2):142-8.
1993: Gao Q; Gu Z; Parniak M A; Cameron J; Cammack N; Boucher C; Wainberg M A
The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine.
Antimicrobial agents and chemotherapy 1993;37(6):1390-2.
1993: Geleziunas R; Arts E J; Boulerice F; Goldman H; Wainberg M A
Effect of 3'-azido-3'-deoxythymidine on human immunodeficiency virus type 1 replication in human fetal brain macrophages.
Antimicrobial agents and chemotherapy 1993;37(6):1305-12.
1993: Soudeyns H; Geleziunas R; Shyamala G; Hiscott J; Wainberg M A
Identification of a novel glucocorticoid response element within the genome of the human immunodeficiency virus type 1.
Virology 1993;194(2):758-68.
1993: Wu J; Amandoron E; Li X; Wainberg M A; Parniak M A
Monoclonal antibody-mediated inhibition of HIV-1 reverse transcriptase polymerase activity. Interaction with a possible deoxynucleoside triphosphate binding domain.
The Journal of biological chemistry 1993;268(14):9980-5.
1993: Wainberg M A; Beaulieu R; Tsoukas C; Thomas R
Detection of zidovudine-resistant variants of HIV-1 in genital fluids.
AIDS (London, England) 1993;7(3):433-4.
1993: Li X; Amandoron E; Wainberg M A; Parniak M A
Generation and characterization of murine monoclonal antibodies reactive against N-terminal and other regions of HIV-1 reverse transcriptase.
Journal of medical virology 1993;39(3):251-9.
1993: Wainberg M A; Salomon H; Spira B; Mercure L; Wainberg J; Nagai K; Bentwich Z; Montaner J
HIV resistance to anti-viral drugs.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1993;26(3):299-308.
1993: Wainberg M A; Geleziunas R; Bour S
The role and fate of the CD4 molecule in lymphocytes and monocytes infected by HIV-1.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1993;26(2):123-36.
1993: Gao Q; Gu Z; Hiscott J; Dionne G; Wainberg M A
Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
Antimicrobial agents and chemotherapy 1993;37(1):130-3.
1993: Wainberg M A; Gu Z; Gao Q; Arts E; Geleziunas R; Bour S; Beaulieu R; Tsoukas C; Singer J; Montaner J
Clinical correlates and molecular basis of HIV drug resistance.
Journal of acquired immune deficiency syndromes 1993;6 Suppl 1():S36-46.
1992: Gu Z; Gao Q; Li X; Parniak M A; Wainberg M A
Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine.
Journal of virology 1992;66(12):7128-35.
1992: Gryllis C; Wainberg M A; Bentwich Z; Gornitsky M; Brenner B G
Increased LAK activity against HIV-infected cell lines in HIV-1+ individuals.
Clinical and experimental immunology 1992;89(3):356-61.
1992: Wainberg M A; Bour S; Geleziunas R; Bentwich Z
[Antiviral strategies in the replication of human immunodeficiency virus]
L'unión médicale du Canada 1992;121(5):307-9, 312-4.
1992: Jiang M; Mak J; Wainberg M A; Parniak M A; Cohen E; Kleiman L
Variable tRNA content in HIV-1IIIB.
Biochemical and biophysical research communications 1992;185(3):1005-15.
1992: Roulston A; D'Addario M; Boulerice F; Caplan S; Wainberg M A; Hiscott J
Induction of monocytic differentiation and NF-kappa B-like activities by human immunodeficiency virus 1 infection of myelomonoblastic cells.
The Journal of experimental medicine 1992;175(3):751-63.
1992: Yao X J; Wainberg M A; Parniak M A
Mechanism of inhibition of HIV-1 infection in vitro by purified extract of Prunella vulgaris.
Virology 1992;187(1):56-62.
1992: Boulerice F; Geleziunas R; Bour S; Li H L; D'Addario M; Roulston A; Hiscott J; Wainberg M A
Differential susceptibilities of U-937 cell clones to infection by human immunodeficiency virus type 1.
Journal of virology 1992;66(2):1183-7.
1992: D'Addario M; Wainberg M A; Hiscott J
Activation of cytokine genes in HIV-1 infected myelomonoblastic cells by phorbol ester and tumor necrosis factor.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(4):1222-9.
1992: Gao Q; Gu Z X; Parniak M A; Li X G; Wainberg M A
In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine.
Journal of virology 1992;66(1):12-9.
1992: Gao Q; Parniak M A; Gu Z; Wainberg M A
Generation of nucleoside-resistant variants of HIV-1 by in vitro selection in the presence of AZT or DDI but no by combinations.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6 Suppl 3():192S-195S.
1992: Wainberg M A; Tremblay M; Rooke R; Fanning M; Tsoukas C; Montaner J S; O'Shaughnessy M; Ruedy J
Characterization of zidovudine resistant variants of HIV-1 isolated from patients on prolonged therapy.
Drugs under experimental and clinical research 1992;18(7):283-90.
1991: Bour S; Boulerice F; Wainberg M A
Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.
Journal of virology 1991;65(12):6387-96.
1991: Brenner B G; Gryllis C; Wainberg M A
Role of antibody-dependent cellular cytotoxicity and lymphokine-activated killer cells in AIDS and related diseases.
Journal of leukocyte biology 1991;50(6):628-40.
1991: Yao X J; Wainberg M A; Richard M; Pollak M
The ability of suramin to block CD4-gp120 binding is reversed in the presence of albumin.
Antimicrobial agents and chemotherapy 1991;35(12):2636-8.
1991: Yao X J; Wainberg M A; Pollak M
The inhibitory effects of suramin on HIV-1 are attenuated in the presence of albumin.
AIDS (London, England) 1991;5(11):1389-91.
1991: Boulerice F; Li X G; Lvovich A; Wainberg M A
Recovery of infectious human immunodeficiency virus type 1 after fusion of defectively infected clones of U-937 cells.
Journal of virology 1991;65(10):5589-92.
1991: Soudeyns H; Yao X I; Gao Q; Belleau B; Kraus J L; Nguyen-Ba N; Spira B; Wainberg M A
Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog.
Antimicrobial agents and chemotherapy 1991;35(7):1386-90.
1991: Rooke R; Parniak M A; Tremblay M; Soudeyns H; Li X G; Gao Q; Yao X J; Wainberg M A
Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs.
Antimicrobial agents and chemotherapy 1991;35(5):988-91.
1991: Geleziunas R; McQuillan A; Malapetsa A; Hutchinson M; Kopriva D; Wainberg M A; Hiscott J; Bramson J; Panasci L
Increased DNA synthesis and repair-enzyme expression in lymphocytes from patients with chronic lymphocytic leukemia resistant to nitrogen mustards.
Journal of the National Cancer Institute 1991;83(8):557-64.
1991: Brenner B G; Gryllis C; Gornitsky M; Cupples W; Wainberg M
Differential effects of chemotherapy-induced and HIV-1-induced immunocompromise on NK and LAK activities using breast cancer and HIV-1 seropositive patient populations.
Anticancer research 1991;11(2):969-74.
1991: Kleiman L; Caudry S; Boulerice F; Wainberg M A; Parniak M A
Incorporation of tRNA into normal and mutant HIV-1.
Biochemical and biophysical research communications 1991;174(3):1272-80.
1991: Geleziunas R; Bour S; Boulerice F; Hiscott J; Wainberg M A
Diminution of CD4 surface protein but not CD4 messenger RNA levels in monocytic cells infected by HIV-1.
AIDS (London, England) 1991;5(1):29-33.
1990: D'Addario M; Roulston A; Wainberg M A; Hiscott J
Coordinate enhancement of cytokine gene expression in human immunodeficiency virus type 1-infected promonocytic cells.
Journal of virology 1990;64(12):6080-9.
1990: Gryllis C; Wainberg M A; Gornitsky M; Brenner B
Diminution of inducible lymphokine-activated killer cell activity in individuals with AIDS-related disorders.
AIDS (London, England) 1990;4(12):1205-12.
1990: Dubreuil M; Sportza L; D'Addario M; Lacoste J; Rooke R; Wainberg M A; Hiscott J
Inhibition of HIV-1 transmission by interferon and 3'-azido-3'-deoxythymidine during de novo infection of promonocytic cells.
Virology 1990;179(1):388-94.
1990: Tremblay M; Numazaki K; Li X G; Gornitsky M; Hiscott J; Wainberg M A
Resistance to infection by HIV-1 of peripheral blood mononuclear cells from HIV-1-infected patients is probably mediated by neutralizing antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(9):2896-901.
1990: Lacoste J; D'Addario M; Roulston A; Wainberg M A; Hiscott J
Cell-specific differences in activation of NF-kappa B regulatory elements of human immunodeficiency virus and beta interferon promoters by tumor necrosis factor.
Journal of virology 1990;64(10):4726-34.
1990: Tremblay M; Wainberg M A
Neutralization of multiple HIV-1 isolates from a single subject by autologous sequential sera.
The Journal of infectious diseases 1990;162(3):735-7.
1990: Boulerice F; Wainberg M A
Inhibition by AZT of HIV-1 replication in acutely infected U-937 cells.
Journal of leukocyte biology 1990;47(6):498-505.
1990: Tremblay M; Meloche S; Sekaly R P; Wainberg M A
Complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in Epstein-Barr virus-carrying B cells.
The Journal of experimental medicine 1990;171(5):1791-6.
1990: Boulerice F; Bour S; Geleziunas R; Lvovich A; Wainberg M A
High frequency of isolation of defective human immunodeficiency virus type 1 and heterogeneity of viral gene expression in clones of infected U-937 cells.
Journal of virology 1990;64(4):1745-55.
1990: Numazaki K; Goldman H; Seemayer T A; Wong I; Wainberg M A
Infection by human cytomegalovirus and rubella virus of cultured human fetal islets of Langerhans.
In vivo (Athens, Greece) 1990;4(1):49-54.
1990: Montaner J S; Le T; Fanning M; Gelmon K; Tsoukas C; Falutz J; O'Shaughnessy M; Wainberg M A; Ruedy J
The effect of zidovudine on platelet count in HIV-infected individuals.
Journal of acquired immune deficiency syndromes 1990;3(6):565-70.
1990: Wainberg M A; Tremblay M; Rooke R; Blain N; Soudeyns H; Parniak M A; Yao X J; Li X G; Fanning M; Montaner J S
Characterization of reverse transcriptase activity and susceptibility to other nucleosides of AZT-resistant variants of HIV-1. Results from the Canadian AZT Multicentre Study.
Annals of the New York Academy of Sciences 1990;616():346-55.
1989: Tremblay M; Gornitsky M; Wainberg M A
Active replication of human immunodeficiency virus type 1 by peripheral blood mononuclear cells following coincubation with herpes viruses.
Journal of medical virology 1989;29(2):109-14.
1989: Gelmon K; Montaner J S; Fanning M; Smith J R; Falutz J; Tsoukas C; Gill J; Wells G; O'Shaughnessy M; Wainberg M
Nature, time course and dose dependence of zidovudine-related side effects: results from the Multicenter Canadian Azidothymidine Trial.
AIDS (London, England) 1989;3(9):555-61.
1989: Tremblay M; Sullivan A K; Rooke R; Geleziunas R; Tsoukas C; Shematek G; Gilmore N; Wainberg M A
New CD4(+) cell line susceptible to infection by HIV-1.
Journal of medical virology 1989;28(4):243-9.
1989: Brenner B G; Dascal A; Margolese R G; Wainberg M A
Natural killer cell function in patients with acquired immunodeficiency syndrome and related diseases.
Journal of leukocyte biology 1989;46(1):75-83.
1989: Tremblay M; Wainberg M A
Susceptibility to AZT of HIV-1 variants grown in Epstein-Barr virus-transformed B cell lines.
The Journal of infectious diseases 1989;160(1):31-6.
1989: Numazaki K; Bai X Q; Goldman H; Wong I; Spira B; Wainberg M A
Infection of cultured human thymic epithelial cells by human immunodeficiency virus.
Clinical immunology and immunopathology 1989;51(2):185-95.
1989: Numazaki K; Goldman H; Wong I; Wainberg M A
Infection of cultured human fetal pancreatic islet cells by rubella virus.
American journal of clinical pathology 1989;91(4):446-51.
1989: Numazaki K; Wainberg M A; McDonald J
Chlamydia trachomatis infections in infants.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 1989;140(6):615-22.
1989: Numazaki K; Goldman H; Wong I; Wainberg M A
Maturation of human fetal and infantile thymic cells in tissue culture.
In vivo (Athens, Greece) 1989;3(2):101-7.
1989: Wainberg M A; Falutz J; Fanning M; Gill J; Gelmon K; Montaner J S; O'Shaughnessy M; Tsoukas C; Ruedy J
Cessation of zidovudine therapy may lead to increased replication of HIV-1.
JAMA : the journal of the American Medical Association 1989;261(6):865-6.
1989: Numazaki K; Goldman H; Wong I; Wainberg M A
Replication of measles virus in cultured human thymic epithelial cells.
Journal of medical virology 1989;27(1):52-8.
1989: Numazaki K; Goldman H; Bai X Q; Wong I; Wainberg M A
Effects of infection by HIV-1, cytomegalovirus, and human measles virus on cultured human thymic epithelial cells.
Microbiology and immunology 1989;33(9):733-45.
1989: Numazaki K; DeStephano L; Wong I; Goldman H; Spira B; Wainberg M A
Replication of cytomegalovirus in human thymic epithelial cells.
Medical microbiology and immunology 1989;178(2):89-98.
1988: Wainberg M A; Dascal A; Blain N; Fitz-Gibbon L; Boulerice F; Numazaki K; Tremblay M
The effect of cyclosporine A on infection of susceptible cells by human immunodeficiency virus type 1.
Blood 1988;72(6):1904-10.
1988: Tremblay M; Fitz-Gibbon L; Wainberg M A
Heterogeneity of HIV-1 replication and antigen expression in EBV-transformed B cell lines.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1988;2(12 Suppl):233S-240S.
1988: Samnotra V; Germinario R J; Wainberg M A
Presence of insulin binding sites on viral particles.
Antiviral research 1988;9(5):285-93.
1988: Numazaki K; Goldman H; Wong I; Wainberg M A
Viral infection of human fetal islets of Langerhans. Replication of human cytomegalovirus in cultured human fetal pancreatic islets.
American journal of clinical pathology 1988;90(1):52-7.
1988: Roy S; Fitz-Gibbon L; Poulin L; Wainberg M A
Infection of human monocytes/macrophages by HIV-1: effect on secretion of IL-1 activity.
Immunology 1988;64(2):233-9.
1988: Wainberg M A; Numazaki K; Destephano L; Wong I; Goldman H
Infection of human thymic epithelial cells by human cytomegalovirus and other viruses: effect on secretion of interleukin 1-like activity.
Clinical and experimental immunology 1988;72(3):415-21.
1988: Wainberg M A; Kendall O; Gilmore N
Vaccine and antiviral strategies against infections caused by human immunodeficiency virus.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 1988;138(9):797-807.
1988: Numazaki K; Destephano L; Goldman H; Wong I; Wainberg M A
Effect of cytomegalovirus on lectin-driven mitogenesis of human thymic and peripheral blood lymphocytes.
In vivo (Athens, Greece) 1988;2(2):133-8.
1988: Numazaki K; Goldman H; Wainberg M A
Effect of co-incubation with cytomegalovirus on growth of interleukin 2-dependent lymphocytes.
Microbial pathogenesis 1988;4(2):137-44.
1988: Roy S; Wainberg M A
Role of the mononuclear phagocyte system in the development of acquired immunodeficiency syndrome (AIDS).
Journal of leukocyte biology 1988;43(1):91-7.
1987: Wainberg M A; Blain N; Fitz-Gibbon L
Differential susceptibility of human lymphocyte cultures to infection by HIV.
Clinical and experimental immunology 1987;70(1):136-42.
1987: Wainberg M A; Blain N; Spira B
Inhibition of human lymphocyte mitogenesis by human and other retroviruses. Differential effect of interleukin-2 in restoration of responsiveness.
AIDS (London, England) 1987;1(2):83-7.
1987: Poulin L; Grise-Miron L; Spira B; Wainberg M A
Altered pp60src kinase activity in regressing tumors induced by Rous sarcoma virus.
Cancer letters 1987;36(1):99-110.
1987: Poulin L; Spira B; Wainberg M A
Studies on pp60src and associated kinase activity in regressing tumors induced by Rous sarcoma virus.
In vivo (Athens, Greece) 1987;1(2):125-30.
1987: Wainberg M A; Portnoy J; Tsoukas C; Gilmore N
Specific stimulation of lymphocytes from patients with AIDS by herpes simplex virus antigens.
Immunology 1987;60(2):275-80.
1987: Poulin L; Wainberg M A
Expression of avian sarcoma virus genes in tumor cells derived from different periods of tumor growth.
Microbial pathogenesis 1987;2(2):101-12.

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