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Kanako Wakabayashi

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Anatomy

Physiology

Concepts & Ideas

Drug Dose Response Relationship

Disorders

Photosensitivity Disorders

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Publications

TOP 3
Tomoka Furukawa; Kanako Wakabayashi; Ai Tamura; Hiroshi Nakagawa; Yoshihiro Morishima; Yoichi Osawa; Toshihisa Ishikawa
Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations.
Shoko Koshiba; R An; Hikaru Saito; Kanako Wakabayashi; Ai Tamura; Toshihisa Ishikawa
Human ABC transporters ABCG2 (BCRP) and ABCG4.
Hiroshi Nakagawa; Ai Tamura; Kanako Wakabayashi; Kazuyuki Hoshijima; Masayuki Komada; Takashi Yoshida; Satoshi Kometani; Takayoshi Matsubara; Kenta Mikuriya; Toshihisa Ishikawa
Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2.

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All Publications

2009: Tomoka Furukawa; Kanako Wakabayashi; Ai Tamura; Hiroshi Nakagawa; Yoshihiro Morishima; Yoichi Osawa; Toshihisa Ishikawa
Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations.
Pharmaceutical research 2009;26(2):469-79.
2008: Shoko Koshiba; R An; Hikaru Saito; Kanako Wakabayashi; Ai Tamura; Toshihisa Ishikawa
Human ABC transporters ABCG2 (BCRP) and ABCG4.
Xenobiotica; the fate of foreign compounds in biological systems 2008;38(7-8):863-88.
2008: Hiroshi Nakagawa; Ai Tamura; Kanako Wakabayashi; Kazuyuki Hoshijima; Masayuki Komada; Takashi Yoshida; Satoshi Kometani; Takayoshi Matsubara; Kenta Mikuriya; Toshihisa Ishikawa
Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2.
The Biochemical journal 2008;411(3):623-31.
2007: Ai Tamura; Yuko Onishi; Ran An; Shoko Koshiba; Kanako Wakabayashi; Kazuyuki Hoshijima; Waldemar Priebe; Takashi Yoshida; Satoshi Kometani; Takayoshi Matsubara; Kenta Mikuriya; Toshihisa Ishikawa
In vitro evaluation of photosensitivity risk related to genetic polymorphisms of human ABC transporter ABCG2 and inhibition by drugs.
Drug metabolism and pharmacokinetics 2007;22(6):428-40.
2007: Kanako Wakabayashi; Hiroshi Nakagawa; Ai Tamura; Shoko Koshiba; Kazuyuki Hoshijima; Masayuki Komada; Toshihisa Ishikawa
Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein.
The Journal of biological chemistry 2007;282(38):27841-6.
2007: Kanako Wakabayashi; Ai Tamura; Toshihisa Ishikawa
[Genetic polymorphisms of human ABC transporter ABCG2: Porphyria risk and ER quality control].
Seikagaku. The Journal of Japanese Biochemical Society 2007;79(2):151-7.
2007: Ai Tamura; Kanako Wakabayashi; Yuko Onishi; Misako Takeda; Yoji Ikegami; Seigo Sawada; Masahisa Tsuji; Yoichi Matsuda; Toshihisa Ishikawa
Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2.
Cancer science 2007;98(2):231-9.
2007: Shoko Koshiba; Takehito Ito; Akira Shiota; Kanako Wakabayashi; Masatsugu Ueda; Hiroshi Ichinose; Toshihisa Ishikawa
Development of polyclonal antibodies specific to ATP-binding cassette transporters human ABCG4 and mouse Abcg4: site-specific expression of mouse Abcg4 in brain.
Journal of experimental therapeutics & oncology 2007;6(4):321-33.
2006: Ai Tamura; Kanako Wakabayashi; Yuko Onishi; Hiroshi Nakagawa; Masahisa Tsuji; Yoichi Matsuda; Toshihisa Ishikawa
Genetic polymorphisms of human ABC transporter ABCG2: development of the standard method for functional validation of SNPs by using the Flp recombinase system.
Journal of experimental therapeutics & oncology 2006;6(1):1-11.
2006: Kanako Wakabayashi; Ai Tamura; Hikaru Saito; Yuko Onishi; Toshihisa Ishikawa
Human ABC transporter ABCG2 in xenobiotic protection and redox biology.
Drug metabolism reviews 2006;38(3):371-91.
2006: Kanako Wakabayashi; Hiroshi Nakagawa; Tatsuhiko Adachi; Isao Kii; Eiry Kobatake; Akira Kudo; Toshihisa Ishikawa
Identification of cysteine residues critically involved in homodimer formation and protein expression of human ATP-binding cassette transporter ABCG2: a new approach using the flp recombinase system.
Journal of experimental therapeutics & oncology 2006;5(3):205-22.
2005: Toshihisa Ishikawa; Ai Tamura; Hikaru Saito; Kanako Wakabayashi; Hiroshi Nakagawa
Pharmacogenomics of the human ABC transporter ABCG2: from functional evaluation to drug molecular design.
Die Naturwissenschaften 2005;92(10):451-63.