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Toshihiko Wakabayashi

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Noriaki Matsubara; Shigeru Miyachi; Keisuke Ota; Nobuhiro Tsukamoto; Takumi Asai; Kenichi Haraguchi; Takashi Izumi; Takao Kojima; Takashi Yamanouchi; Toshihiko Wakabayashi
Endovascular intervention for acute cervical carotid artery occlusion.
Hitoshi Ando; Tsuneyoshi Hoshino; Kengo Ito; Kenichiro Iwami; Shinae Kizaka-Kondoh; Takahiro Kuchimaru; Atsushi Natsume; Fumiharu Ohka; Kiyoshi Saito; Sachi Sugita; Toshihiko Wakabayashi
A hypoxia-inducible factor (HIF)-3α splicing variant, HIF-3α4 impairs angiogenesis in hypervascular malignant meningiomas with epigenetically silenced HIF-3α4.
Zhengang Jiang; Yasukazu Kajita; Takayuki Kitasaka; Kazunari Misawa; Michitaka Fujiwara; Yuichiro Hayashi; Yukitaka Nimura; Toshihiko Wakabayashi; Kensaku Mori
Anatomical annotation on vascular structure in volume rendered images.

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2013: Noriaki Matsubara; Shigeru Miyachi; Keisuke Ota; Nobuhiro Tsukamoto; Takumi Asai; Kenichi Haraguchi; Takashi Izumi; Takao Kojima; Takashi Yamanouchi; Toshihiko Wakabayashi
Endovascular intervention for acute cervical carotid artery occlusion.
Acta neurochirurgica 2013;155(6):1115-23.
2013: Hitoshi Ando; Tsuneyoshi Hoshino; Kengo Ito; Kenichiro Iwami; Shinae Kizaka-Kondoh; Takahiro Kuchimaru; Atsushi Natsume; Fumiharu Ohka; Kiyoshi Saito; Sachi Sugita; Toshihiko Wakabayashi
A hypoxia-inducible factor (HIF)-3α splicing variant, HIF-3α4 impairs angiogenesis in hypervascular malignant meningiomas with epigenetically silenced HIF-3α4.
Biochemical and biophysical research communications 2013;433(1):139-44.
2013: Zhengang Jiang; Yasukazu Kajita; Takayuki Kitasaka; Kazunari Misawa; Michitaka Fujiwara; Yuichiro Hayashi; Yukitaka Nimura; Toshihiko Wakabayashi; Kensaku Mori
Anatomical annotation on vascular structure in volume rendered images.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society 2013;37(2):131-41.
2013: Yasukazu Kajita; Toshiya Nagai; Kouta Yoshida; Toshihiko Wakabayashi
[Mood States in outpatients with lesional epilepsy at the neurosurgical clinic and improvement in mood States after lamotrigine addiction].
No shinkei geka. Neurological surgery 2013;41(3):209-18.
2013: Yoichi Yamada; Akihiro Abe; Shunsuke Baba; Yasushi Furuichi; Kenji Hara; Kenji Ito; Yuichi Izumi; Ophir D Klein; Tetsuro Nagasaka; Sayaka Nakamura; Eri Umemura; Toshihiko Wakabayashi
Injectable bone tissue engineering using expanded mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2013;31(3):572-80.
2013: Rahul Gupta; Kenichi Haraguchi; Takashi Izumi; Noriaki Matsubara; Shigeru Miyachi; Takehiro Naito; Toshihiko Wakabayashi
A unique type of dural arteriovenous fistula at confluence of sinuses treated with endovascular embolization: a case report.
Neurointervention 2013;8(1):34-40.
2013: Takanori Inoue; Masahiko Sugiyama; Toshihiko Wakabayashi; Hideaki Wakita; Hisashi Hattori; Minoru Ueda
Stem cells from human exfoliated deciduous tooth-derived conditioned medium enhance recovery of focal cerebral ischemia in rats.
Tissue engineering. Part A 2013;19(1-2):24-9.
2012: Eriko Tanemura; Yuri Aimi; Yugo Kishida; Tetsuya Nagatani; Kazuhito Takeuchi; Toshihiko Wakabayashi
Quality of life in nonfunctioning pituitary macroadenoma patients before and after surgical treatment.
Acta neurochirurgica 2012;154(10):1895-902.
2012: Kazuya Motomura; Yoko Nakasu; Yoichi Nakazato; Hiroki Namba; Atsushi Natsume; Ryo Nishikawa; Ichiro Takeuchi; Hiroshi Tashiro; Tatsuya Abe; Ichiro Ito; Yukinari Kato; Kazuhiko Mishima; Hiroyuki Momota; Tsutomu Mori; Reiko Watanabe; Toshihiko Wakabayashi
Immunohistochemical analysis-based proteomic subclassification of newly diagnosed glioblastomas.
Cancer science 2012;103(10):1871-9.
2012: Yumiko Okada; Yoshiyuki Okochi; Shigenori Takebayashi; Toshihiko Wakabayashi; Masato Yamashita; Yoshio Ando; Masazumi Fujii; Katsuhiko Kato; Satoshi Maesawa; Takashi Nihashi; Shinji Naganawa
Differentiation of newly diagnosed glioblastoma multiforme and intracranial diffuse large B-cell Lymphoma using (11)C-methionine and (18)F-FDG PET.
Clinical nuclear medicine 2012;37(9):843-9.
2012: Tsutomu Nakashima; Michihiko Sone; Masaaki Teranishi; Hiroko Terasaki; Toshihiko Wakabayashi; Tetsuhiro Yasuma; T Yoshida; Mineo Kondo; Tetsuya Nagatani; Shinji Naganawa
A perspective from magnetic resonance imaging findings of the inner ear: Relationships among cerebrospinal, ocular and inner ear fluids.
Auris, nasus, larynx 2012;39(4):345-55.
2012: Kenichiro Iwami; Norimoto Nakahara; Atsushi Natsume; Hiroyoshi Nishikawa; Masasuke Ohno; Hideho Okada; Yuichiro Sato; Hiroshi Shiku; Shinji Shimato; Satoshi Suzuki; Jun Yoshida; Toshihiko Wakabayashi
Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A*24/A*02 allele.
Cytotherapy 2012;14(6):733-42.
2012: Takehiro Naito; Ichiro Takahashi; Kenichi Haraguchi; Katsuya Ishii; Haruo Isoda; Takashi Izumi; Noriaki Matsubara; Shigeru Miyachi; Toshihiko Wakabayashi
Magnetic resonance fluid dynamics for intracranial aneurysms--comparison with computed fluid dynamics.
Acta neurochirurgica 2012;154(6):993-1001.
2012: Atsushi Natsume; F Ohka; Shinji Shimato; M Takahashi; H Toda; A Enomoto; T Kato; S Kinjo; Y Kondo; T Miyata; K Motomura; Toshihiko Wakabayashi
Girdin maintains the stemness of glioblastoma stem cells.
Oncogene 2012;31(22):2715-24.
2012: Kenichi Haraguchi; Takashi Izumi; Noriaki Matsubara; Shigeru Miyachi; Takehiro Naito; Takumi Asai; Takashi Yamanouchi; Toshihiko Wakabayashi
[Resistance to antiplatelet agents assessed by a point-of-care platelet function test and thromboembolic adverse events in neurointervention].
No shinkei geka. Neurological surgery 2012;40(5):399-406.
2012: Yugo Kishida; Yutaka Kondo; Hiroko Koyama; Keiji Matsuda; Kazuya Motomura; Osamu Nakayama; Atsushi Natsume; Makoto Sato; Masaaki Suzuki; Hiroshi Toda; Yuki Toi; Toshihiko Wakabayashi
Correlation between quantified promoter methylation and enzymatic activity of O6-methylguanine-DNA methyltransferase in glioblastomas.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2012;33(2):373-81.
2012: Kenichiro Iwami; Sayano Kinjo; Hiroyuki Momota; Tetsuya Nagatani; Atsushi Natsume; Toshihiko Wakabayashi
A novel method of intracranial injection via the postglenoid foramen for brain tumor mouse models.
Journal of neurosurgery 2012;116(3):630-5.
2012: Yugo Kishida; Yutaka Kondo; Atsushi Natsume; Fumiharu Ohka; Yasuyuki Okamoto; Kiyoshi Saito; Yoshitaka Sekido; Keiko Shinjo; Ichiro Takeuchi; Byonggu An; Hitoshi Ando; Toshihiko Wakabayashi
Epigenetic subclassification of meningiomas based on genome-wide DNA methylation analyses.
Carcinogenesis 2012;33(2):436-41.
2012: Toshiya Nagai; Daisuke Nakatsubo; Yasukazu Kajita; Katsuhiko Kato; Satoshi Maesawa; Kota Yoshida; Toshihiko Wakabayashi
Preoperative regional cerebral blood flow and postoperative clinical improvement in patients with Parkinson's disease undergoing subthalamic nucleus deep brain stimulation.
Neurologia medico-chirurgica 2012;52(12):865-72.
2012: Yusuke Nishimura; Masaya Takemoto; Ryuichi Fukuyama; Masahito Hara; Atsushi Natsume; Toshihiko Wakabayashi
Intra-extradural dumbbell-shaped hemangioblastoma manifesting as subarachnoid hemorrhage in the cauda equina.
Neurologia medico-chirurgica 2012;52(9):659-65.
2012: Masasuke Ohno; Atsushi Natsume; Toshihiko Wakabayashi
Cytokine therapy.
Advances in experimental medicine and biology 2012;746():86-94.
2012: Fumiharu Ohka; Atsushi Natsume; Toshihiko Wakabayashi
Current trends in targeted therapies for glioblastoma multiforme.
Neurology research international 2012;2012():878425.
2012: Kazuya Motomura; Atsushi Natsume; Toshihiko Wakabayashi
Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas.
Journal of neuro-oncology 2012;106(1):209-11.
2011: Koji Osuka; Chihiro Aoshima; Kimie Atsuzawa; Nobuteru Usuda; Toshihiko Wakabayashi; Yasuo Watanabe; Muneyoshi Yasuda; Masakazu Takayasu
Activation of STAT1 in neurons following spinal cord injury in mice.
Neurochemical research 2011;36(12):2236-43.
2011: Shigemasa Hayashi; Koji Osuka; Masakazu Takayasu; Yasuo Watanabe; Muneyoshi Yasuda; Toshihiko Wakabayashi
Hypothermia enhances the colocalization of calmodulin kinase IIα with neuronal nitric oxide synthase in the hippocampus following cerebral ischemia.
Neuroscience letters 2011;505(3):228-32.
2011: Toshihiko Wakabayashi
[Clinical trial updates for malignant brain tumors].
Rinshō shinkeigaku = Clinical neurology 2011;51(11):853-6.
2011: Kazuya Motomura; Atsushi Natsume; Masazumi Fujii; Motokazu Ito; Hiroyuki Momota; Toshihiko Wakabayashi
Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, ifosfamide and carboplatin chemotherapy and whole-brain radiation therapy.
Leukemia & lymphoma 2011;52(11):2069-75.
2011: Tsuyoshi Ichikawa; Takashi Izumi; Ken-ichi Haraguchi; Noriaki Matsubara; Shigeru Miyachi; Takehiro Naito; Toshihiko Wakabayashi; Naoki Koketsu
Fenestration of a supraclinoid internal carotid artery associated with dual aneurysms: case report.
Neurosurgery 2011;69(4):E1005-8; discussion E1009.
2011: Toru Nagasaka; Takeshi Okamoto; Masanori Tsugeno; Hiroshi Ikeda; Suguru Inao; Toshihiko Wakabayashi
A novel monoshaft bipolar cautery for use in endoscopic intracranial surgery. A short technical note.
Clinical neurology and neurosurgery 2011;113(8):607-11.
2011: Toshihiko Wakabayashi; Tomokazu Aoki; Naoya Hashimoto; Takamasa Kayama; Atsushi Natsume; Ryo Nishikawa; Masatoshi Ogura; Kazuhiko Sugiyama; Hiroshi Takahashi; Jun Takahashi; Jun Yoshida
A multicenter phase I trial of combination therapy with interferon-β and temozolomide for high-grade gliomas (INTEGRA study): the final report.
Journal of neuro-oncology 2011;104(2):573-7.
2011: Kenichiro Iwami; Atsushi Natsume; Toshihiko Wakabayashi
Cytokine networks in glioma.
Neurosurgical review 2011;34(3):253-63; discussion 263-4.
2011: Toru Nagasaka; Masanori Tsugeno; Hiroshi Ikeda; Takeshi Okamoto; Suguru Inao; Toshihiko Wakabayashi
Early recovery and better evacuation rate in neuroendoscopic surgery for spontaneous intracerebral hemorrhage using a multifunctional cannula: preliminary study in comparison with craniotomy.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2011;20(3):208-13.
2011: Kazuya Motomura; Atsushi Natsume; Yugo Kishida; Hiroyuki Higashi; Yutaka Kondo; Yoko Nakasu; Tatsuya Abe; Hiroki Namba; Kenji Wakai; Toshihiko Wakabayashi
Benefits of interferon-β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study.
Cancer 2011;117(8):1721-30.
2011: Masazumi Fujii; Shigeru Miyachi; Noriaki Matsubara; Takeshi Kinkori; Shigenori Takebayashi; Takashi Izumi; Tomotaka Ohshima; Arihito Tsurumi; Osamu Hososhima; Toshihiko Wakabayashi; Jun Yoshida
Selective propofol injection into the M1 segment of the middle cerebral artery (MCA Wada test) reduces adverse effects and enhances the reliability of the Wada test for determining speech dominance.
World neurosurgery 2011;75(3-4):503-8.
2011: Noriaki Matsubara; Shigeru Miyachi; Yoshitaka Nagano; Tomotaka Ohshima; Osamu Hososhima; Takashi Izumi; Arihito Tsurumi; Toshihiko Wakabayashi; Akihito Sano; Hideo Fujimoto
Evaluation of the characteristics of various types of coils for the embolization of intracranial aneurysms with an optical pressure sensor system.
Neuroradiology 2011;53(3):169-75.
2011: Atsushi Natsume; Sayano Kinjo; Kanako Yuki; Takenori Kato; Masasuke Ohno; Kazuya Motomura; Kenichiro Iwami; Toshihiko Wakabayashi
Glioma-initiating cells and molecular pathology: implications for therapy.
Brain tumor pathology 2011;28(1):1-12.
2011: Hiroyuki Momota; Kenichiro Iwami; Masazumi Fujii; Kazuya Motomura; Atsushi Natsume; Jiro Ogino; Tadashi Hasegawa; Toshihiko Wakabayashi
Rhabdoid glioblastoma in a child: case report and literature review.
Brain tumor pathology 2011;28(1):65-70.
2011: Noriaki Matsubara; Shigeru Miyachi; Nobuhiro Tsukamoto; Takashi Izumi; Takehiro Naito; Kenichi Haraguchi; Toshihiko Wakabayashi
Endovascular coil embolization for saccular-shaped blood blister-like aneurysms of the internal carotid artery.
Acta neurochirurgica 2011;153(2):287-94.
2011: Fumiharu Ohka; Kenji Wakai; Tatsuya Abe; Masazumi Fujii; Takashi Fukui; Maki Ito; Kenichiro Iwami; Sayano Kinjo; Yugo Kishida; Yutaka Kondo; Hiroyuki Momota; Kazuya Motomura; Yoko Nakasu; Hiroki Namba; Atsushi Natsume; Toshihiko Wakabayashi
The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma.
PloS one 2011;6(8):e23332.
2011: Takashi Mitsui; Masazumi Fujii; Masatoshi Tsuzaka; Yuichiro Hayashi; Yoshinori Asahina; Toshihiko Wakabayashi
Skin shift and its effect on navigation accuracy in image-guided neurosurgery.
Radiological physics and technology 2011;4(1):37-42.
2010: Kazuya Motomura; Masatoshi Ogura; Atsushi Natsume; Hidenori Yokoyama; Toshihiko Wakabayashi
A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation.
Neuroscience letters 2010;485(1):65-70.
2010: T Kato; Atsushi Natsume; H Toda; H Iwamizu; T Sugita; R Hachisu; R Watanabe; K Yuki; K Motomura; K Bankiewicz; Toshihiko Wakabayashi
Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells.
Gene therapy 2010;17(11):1363-71.
2010: Masaaki Mizuno; Toshihiko Wakabayashi
[Brain tumor].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 8():623-6.
2010: Atsushi Natsume; Kazuya Motomura; Toshihiko Wakabayashi
[The genome atlas of brain tumors].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 8():473-80.
2010: Satoshi Maesawa; Masazumi Fujii; Norimoto Nakahara; Tadashi Watanabe; Toshihiko Wakabayashi; Jun Yoshida
Intraoperative tractography and motor evoked potential (MEP) monitoring in surgery for gliomas around the corticospinal tract.
World neurosurgery 2010;74(1):153-61.
2010: Atsushi Natsume; Yutaka Kondo; Motokazu Ito; Kazuya Motomura; Toshihiko Wakabayashi; Jun Yoshida
Epigenetic aberrations and therapeutic implications in gliomas.
Cancer science 2010;101(6):1331-6.
2010: S Ito; Atsushi Natsume; Shinji Shimato; M Ohno; T Kato; P Chansakul; Toshihiko Wakabayashi; S U Kim
Human neural stem cells transduced with IFN-beta and cytosine deaminase genes intensify bystander effect in experimental glioma.
Cancer gene therapy 2010;17(5):299-306.
2010: Eiji Ito; Kiyoshi Saito; Tetsuya Nagatani; Junzo Ishiyama; Koichi Terada; Mitsuhiro Yoshida; Toshihiko Wakabayashi
Intradural cranial chordoma.
World neurosurgery 2010;73(3):194-7; discussion e31.
2010: Yohei Watanabe; Yuichiro Hayashi; Masazumi Fujii; Miyuki Kimura; Akihiro Sugiura; Masatoshi Tsuzaka; Toshihiko Wakabayashi
[Development of automatic navigation measuring system using template-matching software in image guided neurosurgery].
Nihon Hoshasen Gijutsu Gakkai zasshi 2010;66(2):131-6.
2010: Yasuhiro Nakajima; Koji Osuka; Yukio Seki; Ramesh C Gupta; Masahito Hara; Masakazu Takayasu; Toshihiko Wakabayashi
Taurine reduces inflammatory responses after spinal cord injury.
Journal of neurotrauma 2010;27(2):403-10.
2010: Yoshio Araki; Kazuhiro Yoshikawa; Sho Okamoto; Masaki Sumitomo; Mikio Maruwaka; Toshihiko Wakabayashi
Identification of novel biomarker candidates by proteomic analysis of cerebrospinal fluid from patients with moyamoya disease using SELDI-TOF-MS.
BMC neurology 2010;10():112.
2010: Ken-ichiro Iwami; Atsushi Natsume; Toshihiko Wakabayashi
Gene therapy for high-grade glioma.
Neurologia medico-chirurgica 2010;50(9):727-36.
2009: Takafumi Tanei; Yasukazu Kajita; Takashi Nihashi; Yoshiki Kaneoke; Shigenori Takebayashi; Daisuke Nakatsubo; Toshihiko Wakabayashi
Changes in regional blood flow induced by unilateral subthalamic nucleus stimulation in patients with Parkinson's disease.
Neurologia medico-chirurgica 2009;49(11):507-13.
2009: Kanako Yuki; Atsushi Natsume; Hidenori Yokoyama; Yutaka Kondo; Masasuke Ohno; Takenori Kato; Phassarin Chansakul; Motokazu Ito; Seung-Up Kim; Toshihiko Wakabayashi
Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling.
Cancer letters 2009;284(1):71-9.
2009: Toshihiko Wakabayashi; Masazumi Fujii; Yasukazu Kajita; Atsushi Natsume; Satoshi Maezawa; Jun Yoshida
Advanced new neurosurgical procedure using integrated system of intraoperative MRI and neuronavigation with multimodal neuroradiological images.
Nagoya journal of medical science 2009;71(3-4):101-7.
2009: Eiji Ito; Kiyoshi Saito; Tetsuya Nagatani; Masaaki Teranishi; Yuri Aimi; Toshihiko Wakabayashi
Cavernous sinus thrombophlebitis caused by porphyromonas gingivalis with abscess formation extending to the orbital cavity. Case report.
Neurologia medico-chirurgica 2009;49(8):370-3.
2009: Yohei Watanabe; Masazumi Fujii; Yuichiro Hayashi; Miyuki Kimura; Yasushi Murai; Michiko Hata; Akihiro Sugiura; Masatoshi Tsuzaka; Toshihiko Wakabayashi
Evaluation of errors influencing accuracy in image-guided neurosurgery.
Radiological physics and technology 2009;2(2):120-5.
2009: Masazumi Fujii; Toshihiko Wakabayashi
[Image-guided neurosurgery using intraoperative MRI].
Brain and nerve = Shinkei kenkyū no shinpo 2009;61(7):823-34.
2009: Atsushi Natsume; Yutaka Kondo; Toshihiko Wakabayashi
[Epigenetic analyses of brain tumor stem cells].
Brain and nerve = Shinkei kenkyū no shinpo 2009;61(7):791-8.
2009: Masasuke Ohno; Atsushi Natsume; Masazumi Fujii; Motokazu Ito; Toshihiko Wakabayashi
Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma.
Pediatric blood & cancer 2009;53(1):37-41.
2009: Noriaki Matsubara; Shigeru Miyachi; Yoshitaka Nagano; Tomotaka Ohshima; Osamu Hososhima; Takashi Izumi; Arihito Tsurumi; Toshihiko Wakabayashi; Masamichi Sakaguchi; Akihito Sano; Hideo Fujimoto
A novel pressure sensor with an optical system for coil embolization of intracranial aneurysms. Laboratory investigation.
Journal of neurosurgery 2009;111(1):41-7.
2009: Takafumi Tanei; Yasukazu Kajita; Yoshiki Kaneoke; Shigenori Takebayashi; Daisuke Nakatsubo; Toshihiko Wakabayashi
Staged bilateral deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease.
Acta neurochirurgica 2009;151(6):589-94.
2009: Toshihiko Wakabayashi; Atsushi Natsume; Hisashi Hatano; Masazumi Fujii; Shinji Shimato; Motokazu Ito; Masasuke Ohno; Satoshi Ito; Masatoshi Ogura; Jun Yoshida
p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas.
Neurosurgery 2009;64(3):455-61; discussion 461-2.
2009: Sachie Oi; Atsushi Natsume; Motokazu Ito; Yutaka Kondo; Shinji Shimato; Yuka Maeda; Kiyoshi Saito; Toshihiko Wakabayashi
Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells.
Journal of neuro-oncology 2009;92(1):15-22.
2009: Motokazu Ito; Atsushi Natsume; Hiroki Takeuchi; Shinji Shimato; Masasuke Ohno; Toshihiko Wakabayashi; Jun Yoshida
Type I interferon inhibits astrocytic gliosis and promotes functional recovery after spinal cord injury by deactivation of the MEK/ERK pathway.
Journal of neurotrauma 2009;26(1):41-53.
2008: Toshihiko Wakabayashi; Takamasa Kayama; Ryo Nishikawa; Hiroshi Takahashi; Toshiki Yoshimine; Nobuo Hashimoto; Tomokazu Aoki; Kaoru Kurisu; Atsushi Natsume; Masatoshi Ogura; Jun Yoshida
A multicenter phase I trial of interferon-beta and temozolomide combination therapy for high-grade gliomas (INTEGRA Study).
Japanese journal of clinical oncology 2008;38(10):715-8.
2008: Shinji Shimato; Atsushi Natsume; Toshihiko Wakabayashi; Kunio Tsujimura; Norimoto Nakahara; Jun Ishii; Motokazu Ito; Yoshiki Akatsuka; Kiyotaka Kuzushima; Jun Yoshida
Identification of a human leukocyte antigen-A24-restricted T-cell epitope derived from interleukin-13 receptor alpha2 chain, a glioma-associated antigen.
Journal of neurosurgery 2008;109(1):117-22.
2008: Atsushi Natsume; Toshihiko Wakabayashi; Kunio Tsujimura; Shinji Shimato; Motokazu Ito; Kiyotaka Kuzushima; Yutaka Kondo; Yoshitaka Sekido; Hitomi Kawatsura; Yuji Narita; Jun Yoshida
The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma.
International journal of cancer. Journal international du cancer 2008;122(11):2542-53.
2008: Toshihiko Wakabayashi; Atsushi Natsume; Yoshio Hashizume; Masazumi Fujii; Masaaki Mizuno; Jun Yoshida
A phase I clinical trial of interferon-beta gene therapy for high-grade glioma: novel findings from gene expression profiling and autopsy.
The journal of gene medicine 2008;10(4):329-39.
2008: Atsushi Natsume; Toshihiko Wakabayashi; Dai Ishii; Hideharu Maruta; Masazumi Fujii; Shinji Shimato; Motokazu Ito; Jun Yoshida
A combination of IFN-beta and temozolomide in human glioma xenograft models: implication of p53-mediated MGMT downregulation.
Cancer chemotherapy and pharmacology 2008;61(4):653-9.
2008: Toshihiko Wakabayashi
[Treatment of marignant brain tumor: today and tomorrow].
No shinkei geka. Neurological surgery 2008;36(1):81-2.
2007: Hiroki Takeuchi; Atsushi Natsume; Toshihiko Wakabayashi; Chihiro Aoshima; Shinji Shimato; Motokazu Ito; Jun Ishii; Yuka Maeda; Masahito Hara; Seung Kim; Jun Yoshida
Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner.
Neuroscience letters 2007;426(2):69-74.
2007: Dai Ishii; Atsushi Natsume; Toshihiko Wakabayashi; Hisashi Hatano; Yoshio Asano; Hiroki Takeuchi; Shinji Shimato; Motokazu Ito; Masazumi Fujii; Jun Yoshida
Efficacy of temozolomide is correlated with 1p loss and methylation of the deoxyribonucleic acid repair gene MGMT in malignant gliomas.
Neurologia medico-chirurgica 2007;47(8):341-9; discussion 350.
2007: Yukimi Nakane; Atsushi Natsume; Toshihiko Wakabayashi; Sachie Oi; Motokazu Ito; Suguru Inao; Kiyoshi Saito; Jun Yoshida
Malignant transformation-related genes in meningiomas: allelic loss on 1p36 and methylation status of p73 and RASSF1A.
Journal of neurosurgery 2007;107(2):398-404.
2007: Shinji Shimato; Atsushi Natsume; Hiroki Takeuchi; Toshihiko Wakabayashi; Masazumi Fujii; Motokazu Ito; S Ito; I H Park; Jung Hee Bang; Seung Kim; Jun Yoshida
Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma.
Gene therapy 2007;14(15):1132-42.
2007: Motokazu Ito; Toshihiko Wakabayashi; Atsushi Natsume; Hisashi Hatano; Masazumi Fujii; Jun Yoshida
Genetically heterogeneous glioblastoma recurring with disappearance of 1p/19q losses: case report.
Neurosurgery 2007;61(1):E168-9; discussion E169.
2007: Takaya Tsuno; Atsushi Natsume; Shun Katsumata; Masaaki Mizuno; Mitsugu Fujita; Hirokatsu Osawa; Norimoto Nakahara; Toshihiko Wakabayashi; Yu-ichiro Satoh; Masaki Inagaki; Jun Yoshida
Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells.
Journal of neuro-oncology 2007;83(3):249-58.
2007: Agnieszka Wochna; Edyta Niemczyk; Chieko Kurono; Makoto Masaoka; Jakub Kedzior; Ewa Słomińska; Marcin Lipiński; Toshihiko Wakabayashi
A possible role of oxidative stress in the switch mechanism of the cell death mode from apoptosis to necrosis--studies on rho0 cells.
Mitochondrion 2007;7(1-2):119-24.
2006: Toshihiko Wakabayashi; Atsushi Natsume; Jun Yoshida
[Glioma].
Nihon rinsho. Japanese journal of clinical medicine 2006;64(7):1327-32.
2006: Hisashi Hatano; Toshihiko Wakabayashi; Jun Yoshida
[Pineal lesion tumors (germinoma)].
Nihon rinsho. Japanese journal of clinical medicine 2006;Suppl 1():178-82.
2006: Shinji Shimato; Toshihiko Wakabayashi; Masaaki Mizuno; Norimoto Nakahara; Hisashi Hatano; Atsushi Natsume; Dai Ishii; Yasuhisa Hasegawa; Ikuo Hyodo; Tetsuro Nagasaka; Jun Yoshida
Brain metastases from apocrine carcinoma of the scalp: case report.
Journal of neuro-oncology 2006;77(3):285-9.
2006: Shinji Shimato; Tetsuya Mitsudomi; Takayuki Kosaka; Yasushi Yatabe; Toshihiko Wakabayashi; Masaaki Mizuno; Norimoto Nakahara; Hisashi Hatano; Atsushi Natsume; Dai Ishii; Jun Yoshida
EGFR mutations in patients with brain metastases from lung cancer: association with the efficacy of gefitinib.
Neuro-oncology 2006;8(2):137-44.
2005: Toshihiko Wakabayashi; Kiyoshi Saito; Jun Yoshida
[Neurofibromatosis ].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 9():164-9.
2005: Atsushi Natsume; Dai Ishii; Toshihiko Wakabayashi; Takaya Tsuno; Hisashi Hatano; Masaaki Mizuno; Jun Yoshida
IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide.
Cancer research 2005;65(17):7573-9.
2005: Agnieszka Wochna; Edyta Niemczyk; Chieko Kurono; Makoto Masaoka; Anna Majczak; Jakub Kedzior; Ewa M Slominska; Marcin Lipinski; Toshihiko Wakabayashi
Role of mitochondria in the switch mechanism of the cell death mode from apoptosis to necrosis--studies on rho0 cells.
Journal of electron microscopy 2005;54(2):127-38.
2005: Mitsugu Fujita; Miho Sato; Makoto Nakamura; Kazuko Kudo; Tetsuro Nagasaka; Masaaki Mizuno; Emi Amano; Yoko Okamoto; Yoshihiro Hotta; Hisashi Hatano; Norimoto Nakahara; Toshihiko Wakabayashi; Jun Yoshida
Multicentric atypical teratoid/rhabdoid tumors occurring in the eye and fourth ventricle of an infant: case report.
Journal of neurosurgery 2005;102(3 Suppl):299-302.
2005: Toru Arima; Atsushi Natsume; Hisashi Hatano; Norimoto Nakahara; Mitsugu Fujita; Dai Ishii; Toshihiko Wakabayashi; Manabu Doyu; Tetsuro Nagasaka; Jun Yoshida
Intraventricular chordoid meningioma presenting with Castleman disease due to overproduction of interleukin-6. Case report.
Journal of neurosurgery 2005;102(4):733-7.
2005: John Y K Lee; Toshihiko Wakabayashi; Jun Yoshida
Management and survival of pineoblastoma: an analysis of 34 adults from the brain tumor registry of Japan.
Neurologia medico-chirurgica 2005;45(3):132-41; discussion 141-2.
2004: Mitsugu Fujita; Masaaki Mizuno; Tetsuro Nagasaka; Toshihiko Wakabayashi; Kenkou Maeda; Dai Ishii; Toru Arima; Aie Kawajiri; Masaki Inagaki; Jun Yoshida
Aurora-B dysfunction of multinucleated giant cells in glioma detected by site-specific phosphorylated antibodies.
Journal of neurosurgery 2004;101(6):1012-7.
2004: Anna Hallmann; Ryszard Milczarek; Marcin Lipiński; Ewa Kossowska; Jan Henryk Spodnik; Michał Woźniak; Toshihiko Wakabayashi; Jerzy Klimek
Fast perinuclear clustering of mitochondria in oxidatively stressed human choriocarcinoma cells.
Folia morphologica 2004;63(4):407-12.
2004: Jun Yoshida; Masaaki Mizuno; Toshihiko Wakabayashi
Interferon-beta gene therapy for cancer: basic research to clinical application.
Cancer science 2004;95(11):858-65.
2004: Ewa Kossowka; Agata Zauszkiewicz; Jolanta Kubasik-Juraniec; Cecylia Tukaj; Jan Henryk Spodnik; Anna Hallman; Jerzy Klimek; Emilia Syta; Adam Figarski; Toshihiko Wakabayashi; Michał Woźniak
4-OH-TEMPO prevents the morphological alteration of rat thymocytes primed to apoptosis by oxidative stress inducer ButOOH.
Folia morphologica 2004;63(3):261-5.
2004: Marcin Kaminski; Edyta Niemczyk; Makoto Masaoka; Mariusz Karbowski; Anna Hallmann; Jakub Kedzior; Anna Majczak; Dorota Knap; Yuji Nishizawa; Jiro Usukura; Michał Woźniak; Jerzy Klimek; Toshihiko Wakabayashi
The switch mechanism of the cell death mode from apoptosis to necrosis in menadione-treated human osteosarcoma cell line 143B cells.
Microscopy research and technique 2004;64(3):255-8.
2004: Anna Hallmann; Jerzy Klimek; Makoto Masaoka; Marcin Kaminski; Jakub Kedzior; Anna Majczak; Edyta Niemczyk; Michał Woźniak; Piotr Trzonkowski; Toshihiko Wakabayashi
Partial characterization of human choriocarcinoma cell line JAR cells in regard to oxidative stress.
Acta biochimica Polonica 2004;51(4):1023-38.
2004: Edyta Niemczyk; Anna Majczak; Anna Hallmann; Jakub Kedzior; Michał Woźniak; Toshihiko Wakabayashi
A possible involvement of plasma membrane NAD(P)H oxidase in the switch mechanism of the cell death mode from apoptosis to necrosis in menadione-induced cell injury.
Acta biochimica Polonica 2004;51(4):1015-22.
2004: Jakub Kedzior; Makoto Masaoka; Chieko Kurono; Jan Henryk Spodnik; Anna Hallmann; Anna Majczak; Edyta Niemczyk; Piotr Trzonkowski; Andrzej Myśliwski; Tsuyoshi Soji; Toshihiko Wakabayashi
Changes in physicochemical properties of microtubules lead to the formation of a single spherical structure of mitochondrial assembly enveloping nuclear chromatins.
Journal of electron microscopy 2004;53(6):659-70.
2004: Anna Majczak; Mariusz Karbowski; Marcin Kaminski; Makoto Masaoka; Chieko Kurono; Edyta Niemczyk; Jakub Kedzior; Tsuyoshi Soji; Dorota Knap; Anna Hallmann; Toshihiko Wakabayashi
Modification of physicochemical properties of actin filaments suppresses cell fragmentation in the execution phase of staurosporine-induced apoptotic processes.
Journal of electron microscopy 2004;53(6):635-47.
2004: Jun Yoshida; Masaaki Mizuno; Masazumi Fujii; Yasukazu Kajita; Norimoto Nakahara; Manabu Hatano; Ryuta Saito; Misato Nobayashi; Toshihiko Wakabayashi
Human gene therapy for malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) by in vivo transduction with human interferon beta gene using cationic liposomes.
Human gene therapy 2004;15(1):77-86.
2003: Syuntaro Takasu; Toshitada Takahashi; Sho Okamoto; Noboru Oriuchi; Norihisa Nakayashiki; Kenta Okamoto; Hideki Muramatsu; Takeshi Hayashi; Norimoto Nakahara; Masaaki Mizuno; Toshihiko Wakabayashi; Tetsuya Higuchi; Keigo Endo; Kenichi Kozaki; Osamu Miyaishi; Shinsuke Saga; Ryuzo Ueda; Jun Yoshida; Kazuhiro Yoshikawa
Radioimmunoscintigraphy of intracranial glioma xenograft with a technetium-99m-labeled mouse monoclonal antibody specifically recognizing type III mutant epidermal growth factor receptor.
Journal of neuro-oncology 2003;63(3):247-56.
2003: Norimoto Nakahara; Ian F Pollack; Walter J Storkus; Toshihiko Wakabayashi; Jun Yoshida; Hideho Okada
Effective induction of antiglioma cytotoxic T cells by coadministration of interferon-beta gene vector and dendritic cells.
Cancer gene therapy 2003;10(7):549-58.
2003: Kenkou Maeda; Masaaki Mizuno; Toshihiko Wakabayashi; Syuntarou Takasu; Tetsurou Nagasaka; Masaki Inagaki; Jun Yoshida
Morphological assessment of the development of multinucleated giant cells in glioma by using mitosis-specific phosphorylated antibodies.
Journal of neurosurgery 2003;98(4):854-9.
2003: Akira Ito; Masashige Shinkai; Hiroyuki Honda; Kazuhiro Yoshikawa; Shinsuke Saga; Toshihiko Wakabayashi; Jun Yoshida; Takeshi Kobayashi
Heat shock protein 70 expression induces antitumor immunity during intracellular hyperthermia using magnetite nanoparticles.
Cancer immunology, immunotherapy : CII 2003;52(2):80-8.
2003: Marcin Kaminski; Makoto Masaoka; Mariusz Karbowski; Jakub Kedzior; Yuji Nishizawa; Jiro Usukura; Toshihiko Wakabayashi
Ultrastructural basis for the transition of cell death mode from apoptosis to necrosis in menadione-treated osteosarcoma 143B cells.
Journal of electron microscopy 2003;52(3):313-25.
2002: Jan Henryk Spodnik; Michal Wozniak; Dorota Budzko; Masaaki Teranishi; Mariusz Karbowski; Yuji Nishizawa; Jiro Usukura; Toshihiko Wakabayashi
Mechanism of leflunomide-induced proliferation of mitochondria in mammalian cells.
Mitochondrion 2002;2(3):163-79.
2002: Takanari Ohno; Toshihiko Wakabayashi; Atsuhito Takemura; Jun Yoshida; Akira Ito; Masashige Shinkai; Hiroyuki Honda; Takeshi Kobayashi
Effective solitary hyperthermia treatment of malignant glioma using stick type CMC-magnetite. In vivo study.
Journal of neuro-oncology 2002;56(3):233-9.
2002: Jan Henryk Spodnik; Jakub Kedzior; Aleksandra Gil; Michał Woźniak; Toshihiko Wakabayashi; Giancarlo Falcioni; Lucedio Greci
Divergent effects of quinolinic aminoxyls on mitochondrial ultrastructure and localisation in osteosarcoma 143 B cells.
Folia morphologica 2002;61(4):261-4.
2002: Marcin Kaminski; Mariusz Karbowski; Yu Miyazaki; Jakub Kedzior; Jan Henryk Spodnik; Aleksandra Gil; Michał Woźniak; Toshihiko Wakabayashi
Co-existence of apoptotic and necrotic features within one single cell as a result of menadione treatment.
Folia morphologica 2002;61(4):217-20.
2002: Justyna Gołebiewska; Piotr Rozwadowski; Jan Henryk Spodnik; Narcyz Knap; Toshihiko Wakabayashi; Michał Woźniak
Dual effect of 2-methoxyestradiol on cell cycle events in human osteosarcoma 143B cells.
Acta biochimica Polonica 2002;49(1):59-65.
2001: Akira Ito; Masashige Shinkai; Hiroyuki Honda; Toshihiko Wakabayashi; Jun Yoshida; Takeshi Kobayashi
Augmentation of MHC class I antigen presentation via heat shock protein expression by hyperthermia.
Cancer immunology, immunotherapy : CII 2001;50(10):515-22.
2001: Masashige Shinkai; B Le; Hiroyuki Honda; Kazuhiro Yoshikawa; Kazunori Shimizu; Shinsuke Saga; Toshihiko Wakabayashi; Jun Yoshida; Takeshi Kobayashi
Targeting hyperthermia for renal cell carcinoma using human MN antigen-specific magnetoliposomes.
Japanese journal of cancer research : Gann 2001;92(10):1138-45.
2001: Toshihiko Wakabayashi; Yasukazu Kajita; Masaaki Mizuno; Tetsuro Nagasaka; Jun Yoshida
Efficacy of adjuvant therapy with procarbazine, MCNU, and vincristine for oligodendroglial tumors.
Neurologia medico-chirurgica 2001;41(3):115-9; discussion 119-20.
2001: Toshihiko Wakabayashi; Jun Yoshida; Masaaki Mizuno; Yasukazu Kajita
Intratumoral microinfusion of nimustine (ACNU) for recurrent glioma.
Brain tumor pathology 2001;18(1):23-8.
2001: T Yoshida; Masaaki Mizuno; K Taniguchi; Norihisa Nakayashiki; Toshihiko Wakabayashi; Jun Yoshida
Rat glioma cell death induced by cationic liposome-mediated transfer of the herpes simplex virus thymidine kinase gene followed by ganciclovir treatment.
Journal of surgical oncology 2001;76(1):19-25.
2001: Toshihiko Wakabayashi; Mariusz Karbowski
Structural changes of mitochondria related to apoptosis.
Biological signals and receptors 2001;10(1-2):26-56.
2001: Mariusz Karbowski; Jan Henryk Spodnik; Masaaki Teranishi; Michal Wozniak; Yuji Nishizawa; Jiro Usukura; Toshihiko Wakabayashi
Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells.
Journal of cell science 2001;114(Pt 2):281-91.
2000: Norihisa Nakayashiki; Kazuhiro Yoshikawa; K Nakamura; Nobuo Hanai; K Okamoto; S Okamoto; Masaaki Mizuno; Toshihiko Wakabayashi; Shinsuke Saga; Jun Yoshida; T Takahashi
Production of a single-chain variable fragment antibody recognizing type III mutant epidermal growth factor receptor.
Japanese journal of cancer research : Gann 2000;91(10):1035-43.
2000: Toshihiko Wakabayashi; N Hatano; Yasukazu Kajita; T Yoshida; Masaaki Mizuno; K Taniguchi; Takanari Ohno; Tetsuro Nagasaka; Jun Yoshida
Initial and maintenance combination treatment with interferon-beta, MCNU (Ranimustine), and radiotherapy for patients with previously untreated malignant glioma.
Journal of neuro-oncology 2000;49(1):57-62.
2000: Eiji Tachibana; Kiyoshi Saito; Toshihiko Wakabayashi; Tetsuro Nagasaka; T Furui; Jun Yoshida
Sarcomatous transformation of a prolactinoma associated with development of a fatal internal carotid artery pseudoaneurysm--case report.
Neurologia medico-chirurgica 2000;40(8):427-31.
2000: Y J Hao; Atsushi Natsume; Masaaki Mizuno; K Taniguchi; Toshihiko Wakabayashi; Jun Yoshida
[Correlation between DNA topoisomerase II alpha expression and sensitivity to etoposide in human glioma cell lines].
Gan to kagaku ryoho. Cancer & chemotherapy 2000;27(9):1403-9.
2000: Masaaki Teranishi; J H Spodonik; Mariusz Karbowski; Chieko Kurono; Tsuyoshi Soji; Toshihiko Wakabayashi
Swelling of free-radical-induced megamitochondria causes apoptosis.
Experimental and molecular pathology 2000;68(2):104-23.
2000: Shu Kachi; M Yamazaki; Y Tanaka; Fumio Hayashi; Yozo Miyake; Toshihiko Wakabayashi; Akio Yamazaki; Jiro Usukura
Structural change of bovine retinal cGMP phosphodiesterase by release of its gamma subunit: direct imaging by improved low angle rotary shadowing.
Journal of electron microscopy 2000;49(5):699-708.
2000: Toshihiko Wakabayashi; Yasukazu Kajita; N Hatano; T Thompson; Tetsuro Nagasaka; Jun Yoshida
Clinicopathological study of oligodendroglial tumors: the effectiveness of interferon beta, ACNU/MCNU, and radiation (IAR/IMR) for anaplastic tumors.
Brain tumor pathology 2000;17(1):29-33.
2000: N Hatano; Toshihiko Wakabayashi; Yasukazu Kajita; Masaaki Mizuno; Takanari Ohno; Norihisa Nakayashiki; A Takemura; Jun Yoshida
Efficacy of post operative adjuvant therapy with human interferon beta, MCNU and radiation (IMR) for malignant glioma: comparison among three protocols.
Acta neurochirurgica 2000;142(6):633-8; discussion 639.
2000: Toshihiko Wakabayashi; Jan Henryk Spodnik
Structural changes of mitochondria during free radical-induced apoptosis.
Folia morphologica 2000;59(2):61-75.
2000: Toshihiko Wakabayashi; Masaaki Teranishi; Mariusz Karbowski; Y Nishizawa; Jiro Usukura; Chieko Kurono; Tsuyoshi Soji
Functional aspects of megamitochondria isolated from hydrazine- and ethanol-treated rat livers.
Pathology international 2000;50(1):20-33.
1999: K Taniguchi; Toshihiko Wakabayashi; T Yoshida; Masaaki Mizuno; Kenichi Yoshikawa; Akihiko Kikuchi; N Nakashima; Jun Yoshida
Immunohistochemical staining of DNA topoisomerase IIalpha in human gliomas.
Journal of neurosurgery 1999;91(3):477-82.
1999: Masaaki Teranishi; Mariusz Karbowski; Chieko Kurono; Y Nishizawa; Jiro Usukura; Tsuyoshi Soji; Toshihiko Wakabayashi
Effects of coenzyme Q10 on changes in the membrane potential and rate of generation of reactive oxygen species in hydrazine- and chloramphenicol-treated rat liver mitochondria.
Archives of biochemistry and biophysics 1999;366(1):157-67.
1999: I A Bouhon; Masashige Shinkai; Hiroyuki Honda; M Mizuno; Toshihiko Wakabayashi; J Yoshida; Takeshi Kobayashi
Synergism between mild hyperthermia and interferon-beta gene expression.
Cancer letters 1999;139(2):153-8.
1999: Shu Kachi; Yuji Nishizawa; Elena V Olshevskaya; Akio Yamazaki; Yozo Miyake; Toshihiko Wakabayashi; Alexander M Dizhoor; Jiro Usukura
Detailed localization of photoreceptor guanylate cyclase activating protein-1 and -2 in mammalian retinas using light and electron microscopy.
Experimental eye research 1999;68(4):465-73.
1999: Mariusz Karbowski; Chieko Kurono; Michal Wozniak; M Ostrowski; Masaaki Teranishi; Tsuyoshi Soji; Toshihiko Wakabayashi
Cycloheximide and 4-OH-TEMPO suppress chloramphenicol-induced apoptosis in RL-34 cells via the suppression of the formation of megamitochondria.
Biochimica et biophysica acta 1999;1449(1):25-40.
1999: Mariusz Karbowski; Chieko Kurono; Michal Wozniak; M Ostrowski; Masaaki Teranishi; Y Nishizawa; Jiro Usukura; Tsuyoshi Soji; Toshihiko Wakabayashi
Free radical-induced megamitochondria formation and apoptosis.
Free radical biology & medicine 1999;26(3-4):396-409.
1999: N Watanabe; Yozo Miyake; Toshihiko Wakabayashi; Jiro Usukura
Periciliary structure of developing rat photoreceptor cells. A deep etch replica and freeze substitution study.
Journal of electron microscopy 1999;48(6):929-35.
1999: Masaaki Teranishi; Mariusz Karbowski; Chieko Kurono; Tsuyoshi Soji; Toshihiko Wakabayashi
Two types of the enlargement of mitochondria related to apoptosis: simple swelling and the formation of megamitochondria.
Journal of electron microscopy 1999;48(5):637-51.
1999: Toshihiko Wakabayashi
Structural changes of mitochondria related to apoptosis: swelling and megamitochondria formation.
Acta biochimica Polonica 1999;46(2):223-37.
1998: Toshihiko Wakabayashi; Masaaki Mizuno; Jun Yoshida
Gene therapy of central nervous system tumors.
Neurologia medico-chirurgica 1998;38(11):763-71.
1998: Y Okamoto; H Onogi; R Honda; H Yasuda; Toshihiko Wakabayashi; Yuji Nimura; Masatoshi Hagiwara
cdc2 kinase-mediated phosphorylation of splicing factor SF2/ASF.
Biochemical and biophysical research communications 1998;249(3):872-8.
1998: N Bucur; Masaaki Mizuno; Toshihiko Wakabayashi; Jun Yoshida
Growth inhibition of experimental glioma by human interferon-beta superinduced by cationic liposomes entrapping polyinosilic:polycytidilic acid.
Neurologia medico-chirurgica 1998;38(8):469-73; discussion 473-4.
1998: M Yanase; Masashige Shinkai; Hiroyuki Honda; Toshihiko Wakabayashi; Jun Yoshida; Takeshi Kobayashi
Antitumor immunity induction by intracellular hyperthermia using magnetite cationic liposomes.
Japanese journal of cancer research : Gann 1998;89(7):775-82.
1998: M Yanase; Masashige Shinkai; Hiroyuki Honda; Toshihiko Wakabayashi; Jun Yoshida; Takeshi Kobayashi
Intracellular hyperthermia for cancer using magnetite cationic liposomes: an in vivo study.
Japanese journal of cancer research : Gann 1998;89(4):463-9.
1998: N Kuroyanagi; H Onogi; Toshihiko Wakabayashi; Masatoshi Hagiwara
Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles.
Biochemical and biophysical research communications 1998;242(2):357-64.
1998: Takahiro Kamimoto; Y Nagai; H Onogi; Yoshinao Muro; Toshihiko Wakabayashi; Masatoshi Hagiwara
Dymple, a novel dynamin-like high molecular weight GTPase lacking a proline-rich carboxyl-terminal domain in mammalian cells.
The Journal of biological chemistry 1998;273(2):1044-51.
1998: S Ohta; J Yoshida; S Yamamoto; K Uemura; Toshihiko Wakabayashi; M Mizuno; Takashi Sakurai; Susumu Terakawa
Video-enhanced microscopic visualization of apoptotic cell death caused by anti-Fas antibody in living human glioma cells.
Brain tumor pathology 1998;15(1):19-21.
1998: T Matsuhashi; Mariusz Karbowski; X Liu; Jiro Usukura; Michal Wozniak; Toshihiko Wakabayashi
Complete suppresion of ethanol-induced formation of megamitochondria by 4-hydroxy-2,2,6,6-tetramethyl-piperidine-1-oxyl (4-OH-TEMPO).
Free radical biology & medicine 1998;24(1):139-47.
1997: Mariusz Karbowski; Chieko Kurono; Y Nishizawa; Y Horie; Tsuyoshi Soji; Toshihiko Wakabayashi
Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes.
Biochimica et biophysica acta 1997;1349(3):242-50.
1997: Toshihiko Wakabayashi; Jun Yoshida; J Ishiyama; Masaaki Mizuno
Antitumor activity of recombinant human tumor necrosis factor-alpha (rH-TNF alpha) and liposome-entrapped rH-TNF alpha.
Neurologia medico-chirurgica 1997;37(10):739-45; discussion 745-6.
1997: M Yanase; Masashige Shinkai; Hiroyuki Honda; Toshihiko Wakabayashi; Jun Yoshida; Takeshi Kobayashi
Intracellular hyperthermia for cancer using magnetite cationic liposomes: ex vivo study.
Japanese journal of cancer research : Gann 1997;88(7):630-2.
1997: K Sugiura; Yoshinao Muro; Y Nagai; Takahiro Kamimoto; Toshihiko Wakabayashi; M Ohashi; Masatoshi Hagiwara
Expression cloning and intracellular localization of a human ZF5 homologue.
Biochimica et biophysica acta 1997;1352(1):23-6.
1997: Toshihiko Wakabayashi; Jun Yoshida; T Takaoka; T Sadamoto; Masaaki Mizuno; S Kimura
Enzyme immunoassay of glioma cell tenascin secretion and augmentation by tumor necrosis factor-alpha.
Neurologia medico-chirurgica 1997;37(5):392-7; discussion 397-8.
1997: K Ichimi; Jun Yoshida; Suguru Inao; Toshihiko Wakabayashi
Abducens nerve neurinoma--case report.
Neurologia medico-chirurgica 1997;37(2):197-200.
1997: Toshihiko Wakabayashi; K Adachi; T Matsuhashi; Michal Wozniak; J Antosiewicz; M Karbowsky
Suppression of the formation of megamitochondria by scavengers for free radicals.
Molecular aspects of medicine 1997;18 Suppl():S51-61.
1997: T Matsuhashi; X Liu; Mariusz Karbowski; Michal Wozniak; J Antosiewicz; Toshihiko Wakabayashi
Role of free radicals in the mechanism of the hydrazine-induced formation of megamitochondria.
Free radical biology & medicine 1997;23(2):285-93.
1996: Masashige Shinkai; M Yanase; Hiroyuki Honda; Toshihiko Wakabayashi; Jun Yoshida; T Kobayashi
Intracellular hyperthermia for cancer using magnetite cationic liposomes: in vitro study.
Japanese journal of cancer research : Gann 1996;87(11):1179-83.
1996: M Suzuki; Hiroyuki Honda; T Kobayashi; Toshihiko Wakabayashi; Jun Yoshida; M Takahashi
Development of a target-directed magnetic resonance contrast agent using monoclonal antibody-conjugated magnetic particles.
Nōshuyō byōri = Brain tumor pathology 1996;13(2):127-32.
1996: Hidechika Okada; Koichi Miyamura; T Itoh; M Hagiwara; Toshihiko Wakabayashi; Masaaki Mizuno; Peter Colosi; GJ Kurtzman; Jun Yoshida
Gene therapy against an experimental glioma using adeno-associated virus vectors.
Gene therapy 1996;3(11):957-64.
1996: T Matsuhashi; X Liu; Y Nishizawa; Jiro Usukura; M Wozniak; Toshihiko Wakabayashi
Mechanism of the formation of megamitochondria in the mouse liver induced by chloramphenicol.
Toxicology letters 1996;86(1):47-54.
1995: K Adachi; T Matsuhashi; Y Nishizawa; Jiro Usukura; J Popinigis; Toshihiko Wakabayashi
Suppression of the hydrazine-induced formation of megamitochondria in the rat liver by coenzyme Q10.
Toxicologic pathology 1995;23(6):667-76.
1995: K Adachi; T Matsuhashi; Y Nishizawa; Jiro Usukura; J Popinigis; Toshihiko Wakabayashi
Studies on urea synthesis in the liver of rats treated chronically with ethanol using perfused livers, isolated hepatocytes, and mitochondria.
Biochemical pharmacology 1995;50(9):1391-9.
1995: K Nehashi; Jun Yoshida; Toshihiko Wakabayashi; M Nagata; J Utsumi; N Naruse; K Sugita
Growth inhibition of human glioma cells by superinduced human interferon-beta.
Neurologia medico-chirurgica 1995;35(10):719-22.
1995: J Antosiewicz; J Popinigis; H Ishiguro; T Hayakawa; Toshihiko Wakabayashi
Cerulein-induced acute pancreatitis diminished vitamin E concentration in plasma and increased in the pancreas.
International journal of pancreatology : official journal of the International Association of Pancreatology 1995;17(3):231-6.
1995: Toshihiko Wakabayashi; Jun Yoshida; H Okada; K Sugita; K Itoh; M Tadokoro; M Ohshima
Radioimaging of human glioma by indium-111 labeled G-22 anti-glioma monoclonal antibody.
Nōshuyō byōri = Brain tumor pathology 1995;12(2):105-10.
1995: K Harada; Jun Yoshida; Toshihiko Wakabayashi; H Okabe; K Sugita
A super long-acting LH-RH analogue induces regression of hypothalamic hamartoma associated with precocious puberty.
Acta neurochirurgica 1995;137(1-2):102-5.
1994: X Liu; K Seno; Y Nishizawa; F Hayashi; Akio Yamazaki; H Matsumoto; Toshihiko Wakabayashi; Jiro Usukura
Ultrastructural localization of retinal guanylate cyclase in human and monkey retinas.
Experimental eye research 1994;59(6):761-8.
1994: K Adachi; T Matsuhashi; Y Nishizawa; Jiro Usukura; M Momota; J Popinigis; Toshihiko Wakabayashi
Further studies on physicochemical properties of mitochondrial membranes during the formation process of megamitochondria in the rat liver by hydrazine.
Experimental and molecular pathology 1994;61(2):134-51.
1994: Jun Yoshida; Toshihiko Wakabayashi; S Okamoto; S Kimura; K Washizu; K Kiyosawa; K Mokuno
Tenascin in cerebrospinal fluid is a useful biomarker for the diagnosis of brain tumour.
Journal of neurology, neurosurgery, and psychiatry 1994;57(10):1212-5.
1994: J Antosiewicz; Y Nishizawa; X Liu; J Usukura; Toshihiko Wakabayashi
Suppression of the hydrazine-induced formation of megamitochondria in the rat liver by alpha-tocopherol.
Experimental and molecular pathology 1994;60(3):173-87.
1994: K Harada; Jun Yoshida; Toshihiko Wakabayashi; K Sugita
[Clinico-pathological investigation for infantile brain stem glioma: report of two cases].
Nōshuyō byōri = Brain tumor pathology 1994;11(1):65-70.
1994: Jun Yoshida; Y Kajita; Toshihiko Wakabayashi; K Sugita
Long-term follow-up results of 175 patients with malignant glioma: importance of radical tumour resection and postoperative adjuvant therapy with interferon, ACNU and radiation.
Acta neurochirurgica 1994;127(1-2):55-9.
1994: Toshihiko Wakabayashi; Jun Yoshida; M Mizuno; K Sugita; K Itoh; M Tadokoro; M Oshima
Radioimmunolocalization of human brain tumor: fundamental studies with indium-111 labeled monoclonal antibody G-22.
Nōshuyō byōri = Brain tumor pathology 1994;11(2):177-80.
1993: T Tashiro; Jun Yoshida; Toshihiko Wakabayashi; K Sugita; H Abe
Primary intracranial germinoma involving the medulla oblongata--case report.
Neurologia medico-chirurgica 1993;33(4):251-4.
1992: Toshihiko Wakabayashi; Jun Yoshida; Masaaki Mizuno; A Kito; K Sugita
Effectiveness of interferon-beta, ACNU, and radiation therapy in pediatric patients with brainstem glioma.
Neurologia medico-chirurgica 1992;32(13):942-6.
1992: K Adachi; M Momota; Y Teranishi; R Ueki; M Hagiwara; Toshihiko Wakabayashi; J Popinigis
Effects of alkyl alcohols and related chemicals on rat liver structure and function. III. Physiochemical properties of ethanol-, propanol- and butanol- treated rat liver mitochondrial membranes.
Acta pathologica japonica 1992;42(8):549-57.
1992: Y Sakai; K Adachi; T Hayakawa; Toshihiko Wakabayashi
Isolation and some biochemical properties of porcine pancreas mitochondria.
Nagoya journal of medical science 1992;54(1-4):41-57.
1992: Jun Yoshida; Toshihiko Wakabayashi; Masaaki Mizuno; K Sugita; H Seo; M Oshima; M Tadokoro; S Sakuma
Tumor-specific binding of radiolabeled G-22 monoclonal antibody in glioma patients.
Neurologia medico-chirurgica 1992;32(3):125-9.
1992: S Sai; Jiro Usukura; T Shinohara; Toshihiko Wakabayashi; S Awaya
S-antigen localization in developing rds mouse retina.
Japanese journal of ophthalmology 1992;36(3):331-41.
1991: Toshihiko Wakabayashi; K Adachi; J Popinigis
Effects of alkyl alcohols and related chemicals on rat liver structure and function. I. Induction of two distinct types of megamitochondria.
Acta pathologica japonica 1991;41(6):405-13.
1991: M Terasawa; Masatoshi Hagiwara; T Hachiya; R Kobayashi; S Obata; Toshihiko Wakabayashi; H Hidaka
Identification and characterization of protein kinase C-related enzymes in frog retina.
Archives of biochemistry and biophysics 1991;287(2):213-7.
1991: K Adachi; Toshihiko Wakabayashi; J Popinigis
Effects of alkyl alcohols and related chemicals on rat liver structure and function. II. Some biochemical properties of ethanol-, propanol- and butanol-treated rat liver mitochondria.
Acta pathologica japonica 1991;41(6):414-27.
1991: J Popinigis; J Antosiewicz; Massimo Crimi; G Lenaz; Toshihiko Wakabayashi
Human skeletal muscle: participation of different metabolic activities in oxidation of L-lactate.
Acta biochimica Polonica 1991;38(1):169-75.
1987: Toshihiko Wakabayashi; K Yamashita; K Adachi; K Kawai; M Iijima; K Gekko; T Tsudzuki; J Popinigis; M Momota
Changes in physicochemical properties of mitochondrial membranes during the formation process of megamitochondria induced by hydrazine.
Toxicology and applied pharmacology 1987;87(2):235-48.