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Edward Wakeland

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Satoko Arai; Shin-Ichiro Honda; Yoshihiro Iwamura; Toshihiro Kai; Jun Kurokawa; Quan-Zhen Li; Natsumi Maehara; Nobuyuki Matsuhashi; Kensuke Miyake; Mayumi Mori; Kumiko Morita; Yuji Motoi; Katsuhiko Nakashima; Masato Ogishi; Osamu Ohara; Akira Shibuya; Edward K Wakeland; Ken-Ichi Yamamura; Toru Miyazaki
Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells.
Mala Dutta; Julio Gomez-Rodriguez; Sun-Hee Hwang; Zachary J Kraus; Sang-Yun Lee; Jennifer L Cannons; Jun Cheng; Edward K Wakeland; David L Wiest; Pamela L Schwartzberg
A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.
Rui-Jun Su; Kasthuribai Viswanathan; Edward K Wakeland; Jasmin Wang; Yadong Yang; Xiangdong Fang; Amanda Neises; Kimberly J Payne; Xiao-Bing Zhang
Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells.

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2013: Satoko Arai; Shin-Ichiro Honda; Yoshihiro Iwamura; Toshihiro Kai; Jun Kurokawa; Quan-Zhen Li; Natsumi Maehara; Nobuyuki Matsuhashi; Kensuke Miyake; Mayumi Mori; Kumiko Morita; Yuji Motoi; Katsuhiko Nakashima; Masato Ogishi; Osamu Ohara; Akira Shibuya; Edward K Wakeland; Ken-Ichi Yamamura; Toru Miyazaki
Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells.
Cell reports 2013;3(4):1187-98.
2013: Mala Dutta; Julio Gomez-Rodriguez; Sun-Hee Hwang; Zachary J Kraus; Sang-Yun Lee; Jennifer L Cannons; Jun Cheng; Edward K Wakeland; David L Wiest; Pamela L Schwartzberg
A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(5):2121-8.
2013: Rui-Jun Su; Kasthuribai Viswanathan; Edward K Wakeland; Jasmin Wang; Yadong Yang; Xiangdong Fang; Amanda Neises; Kimberly J Payne; Xiao-Bing Zhang
Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells.
PloS one 2013;8(4):e59908.
2013: Maroof Hasan; James Koch; Min Ae Lee-Kirsch; Beth Levine; Asit K Pattnaik; Dinesh Rakheja; Edward K Wakeland; James Brugarolas; Igor Dozmorov; Nan Yan
Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes.
Nature immunology 2013;14(1):61-71.
2012: Sun-Hee Hwang; Leigh A Jones; Huiyin Lee; Edward K Wakeland; Miwako Yamamoto; Felix Yarovinsky; Xin J Zhou; John E Connolly; Maria A Curotto de Lafaille; Jivanaah Dayalan; Richard Hopkins; Anna-Marie Fairhurst
B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(12):5786-96.
2012: Yanick J Crow; Edward K Wakeland
Autoimmunity.
Current opinion in immunology 2012;24(6):649-50.
2012: Yajuan Li; Xiuyan Ruan; Edward K Wakeland; Hai Wang; Bin Yang; Jichen Yang; Yadong Yang; Quanzhen Li; Xiangdong Fang
Influence of carbon monoxide on growth and apoptosis of human umbilical artery smooth muscle cells and vein endothelial cells.
International journal of biological sciences 2012;8(10):1431-46.
2011: Dorothy Yuan; Xin J Zhou; Suwannee Thet; Edward K Wakeland; Tam Dang
The role of NK cells in the development of autoantibodies.
Autoimmunity 2011;44(8):641-51.
2011: Edward K Wakeland
Connective tissue diseases: Correlating genotypes with disease phenotypes in SLE.
Nature reviews. Rheumatology 2011;7(11):623-4.
2011: Shipra Vaishnava; Edward K Wakeland; Miwako Yamamoto; Xiaofei Yu; Omry Koren; Ruth Ley; Kelly A Ruhn; Kari M Severson; Lora V Hooper
The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine.
Science (New York, N.Y.) 2011;334(6053):255-8.
2011: Ekta Rai; Edward K Wakeland
Genetic predisposition to autoimmunity--what have we learned?
Seminars in immunology 2011;23(2):67-83.
2011: Quan-Zhen Li; Yun Lian; Valerie Branch; Benjamin F Chong; David R Karp; Jiexia Quan; Edward K Wakeland; Jinchun Zhou; Nancy J Olsen
Risk factors for ANA positivity in healthy persons.
Arthritis research & therapy 2011;13(2):R38.
2010: Andrew Wang; Frederic Batteux; Edward K Wakeland
The role of SLAM/CD2 polymorphisms in systemic autoimmunity.
Current opinion in immunology 2010;22(6):706-14.
2010: Andrew Wang; Philippe Guilpain; Benjamin F Chong; Sandrine Chouzenoux; Loïc Guillevin; Yong Du; Xin J Zhou; Fangming Lin; Anna-Marie Fairhurst; Christopher Boudreaux; Christian Roux; Edward K Wakeland; Laurie S Davis; Frederic Batteux; Chandra Mohan
Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus.
Arthritis and rheumatism 2010;62(11):3436-46.
2010: Idil Aktan; Alan Chant; Zachary D Borg; David E Damby; Paige C Leenstra; Graham W J Lilley; Joseph Petty; Benjamin T Suratt; Cory Teuscher; Edward K Wakeland; Matthew E Poynter; Graham W G Lilley; Jonathan Boyson
Slam haplotypes modulate the response to lipopolysaccharide in vivo through control of NKT cell number and function.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):144-56.
2010: Quan-Zhen Li; Jinchun Zhou; Y Lian; B Zhang; Valerie Branch; F Carr-Johnson; D R Karp; Chandra Mohan; Edward K Wakeland; Nancy J Olsen
Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes.
Clinical and experimental immunology 2010;159(3):281-91.
2010: Jennifer L Cannons; Hai Qi; Kristina T Lu; Mala Dutta; Julio Gomez-Rodriguez; Jun Cheng; Edward K Wakeland; Ronald N Germain; Pamela L Schwartzberg
Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84.
Immunity 2010;32(2):253-65.
2009: Anna-Marie Fairhurst; Chun Xie; Yuyang Fu; Andrew Wang; Christopher Boudreaux; Xin J Zhou; Ricardo Cibotti; Anthony J Coyle; John E Connolly; Edward K Wakeland; Chandra Mohan
Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(10):6831-8.
2009: Bahram Namjou; Courtney Gray-McGuire; Andrea L Sestak; Gary S Gilkeson; Chaim O Jacob; J T Merrill; Judith A James; Edward K Wakeland; Quan-Zhen Li; Carl D Langefeld; J Divers; J Ziegler; Kathy L Moser; Jennifer A Kelly; Kenneth M Kaufman; John B Harley
Evaluation of C1q genomic region in minority racial groups of lupus.
Genes and immunity 2009;10(5):517-24.
2009: Quan-Zhen Li; Jinchun Zhou; R Yang; M Yan; Q Ye; K Liu; S Liu; X Shao; L Li; Xin J Zhou; Edward K Wakeland; Chandra Mohan
The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis.
Genes and immunity 2009;10(5):503-8.
2009: Andrew Wang; Anna-Marie Fairhurst; Katalin Tus; Srividya Subramanian; Yang Liu; Fangming Lin; Peter Igarashi; Xin J Zhou; Frederic Batteux; Donald Wong; Edward K Wakeland; Chandra Mohan
CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4448-58.
2008: paula jennings; Alice Chan; Pamela Schwartzberg; Edward K Wakeland; Dorothy Yuan
Antigen-specific responses and ANA production in B6.Sle1b mice: a role for SAP.
Journal of autoimmunity 2008;31(4):345-53.
2008: Anna-Marie Fairhurst; Sun-hee Hwang; Andrew Wang; Xiang-Hong Tian; Christopher Boudreaux; Xin J Zhou; Jose Casco; Quan-Zhen Li; John E Connolly; Edward K Wakeland
Yaa autoimmune phenotypes are conferred by overexpression of TLR7.
European journal of immunology 2008;38(7):1971-8.
2008: Anna-Marie Fairhurst; Alexis Mathian; John E Connolly; Andrew Wang; Hillery F Gray; Tiffany A George; Christopher D Boudreaux; Xin J Zhou; Quan-Zhen Li; Sophie Koutouzov; Jacques Banchereau; Edward K Wakeland
Systemic IFN-alpha drives kidney nephritis in B6.Sle123 mice.
European journal of immunology 2008;38(7):1948-60.
2008: Jennifer A Kelly; J M Kelley; Kenneth M Kaufman; Jeff Kilpatrick; Gail R Bruner; J T Merrill; Judith A James; S G Frank; E Reams; Elizabeth E Brown; A W Gibson; M C Marion; Carl D Langefeld; Quan-Zhen Li; D R Karp; Edward K Wakeland; Michelle Petri; R Ramsey-Goldman; J D Reveille; L M Vilá; G S Alarcón; Robert P Kimberly; John B Harley; J C Edberg
Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans.
Genes and immunity 2008;9(3):187-94.
2008: Swapan K Nath; Shizhong Han; Xana R Kim-Howard; Jennifer A Kelly; Parvathi Viswanathan; Gary S Gilkeson; Wei Chen; Cheng Zhu; Rodger P McEver; Robert P Kimberly; Marta E Alarcón-Riquelme; Timothy J Vyse; Quan-Zhen Li; Edward K Wakeland; Joan T Merrill; Judith A James; Kenneth M Kaufman; Guthridge Joel; John B Harley
A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.
Nature genetics 2008;40(2):152-4.
2008: N Limaye; K A Belobrajdic; Amy E Wandstrat; François Bonhomme; Scott V Edwards; Edward K Wakeland
Prevalence and evolutionary origins of autoimmune susceptibility alleles in natural mouse populations.
Genes and immunity 2008;9(1):61-8.
2007: K Liu; Quan-Zhen Li; Y Yu; Chaoying Liang; Srividya Subramanian; Z Zeng; H W Wang; Chun Xie; Xin J Zhou; Chandra Mohan; Edward K Wakeland
Sle3 and Sle5 can independently couple with Sle1 to mediate severe lupus nephritis.
Genes and immunity 2007;8(8):634-45.
2007: Chun Xie; Rahul Patel; Tianfu Wu; Jiankun Zhu; Tamika Henry; Madhavi Bhaskarabhatla; Renuka Samudrala; Katalin Tus; Yimei Gong; Hui Zhou; Edward K Wakeland; Xin J Zhou; Chandra Mohan
PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr.
International immunology 2007;19(4):509-22.
2007: Satoko Arai; Katsuhisa Miyake; Renate Voit; Shino Nemoto; Edward K Wakeland; Ingrid Grummt; Toru Miyazaki
Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2289-94.
2007: Quan-Zhen Li; Jinchun Zhou; Amy E Wandstrat; F Carr-Johnson; Valerie Branch; D R Karp; Chandra Mohan; Edward K Wakeland; Nancy J Olsen
Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes.
Clinical and experimental immunology 2007;147(1):60-70.
2006: Maria H Johansson; Mesha Austin Taylor; Maja Jagodic; Katalin Tus; John Schatzle; Edward K Wakeland; Michael Bennett
Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):7923-9.
2006: Alice Y Chan; Jill M Westcott; Jill M Mooney; Edward K Wakeland; John Schatzle
The role of SAP and the SLAM family in autoimmunity.
Current opinion in immunology 2006;18(6):656-64.
2006: Amy E Wandstrat; Ferdicia Carr-Johnson; Valerie Branch; Hillery Gray; Anna-Marie Fairhurst; Andreas Reimold; David Karp; Edward K Wakeland; Nancy J Olsen
Autoantibody profiling to identify individuals at risk for systemic lupus erythematosus.
Journal of autoimmunity 2006;27(3):153-60.
2006: Edward K Wakeland
Modern immunogenetics: simple questions with complex answers.
Current opinion in immunology 2006;18(5):605-7.
2006: Srividya Subramanian; Katalin Tus; Quan-Zhen Li; Andrew Wang; Xiang-Hong Tian; Jinchun Zhou; Chaoying Liang; Guy Bartov; Lisa D McDaniel; Xin J Zhou; Roger A Schultz; Edward K Wakeland
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(26):9970-5.
2006: Kirthi Raman Kumar; Liunan Li; Mei Yan; Madhavi Bhaskarabhatla; Angela B Mobley; Charles Nguyen; Jill M Mooney; John Schatzle; Edward K Wakeland; Chandra Mohan
Regulation of B cell tolerance by the lupus susceptibility gene Ly108.
Science (New York, N.Y.) 2006;312(5780):1665-9.
2006: Aleksandar Stanic; C Michael Stein; Adam C Morgan; Sergio Fazio; MacRae F Linton; Edward K Wakeland; Nancy J Olsen; Amy S Major
Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosus.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(18):7018-23.
2006: Anna-Marie Fairhurst; Amy E Wandstrat; Edward K Wakeland
Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease.
Advances in immunology 2006;92():1-69.
2005: Srividya Subramanian; Young-Sun Yim; Kui Liu; Katalin Tus; Xin J Zhou; Edward K Wakeland
Epistatic suppression of systemic lupus erythematosus: fine mapping of Sles1 to less than 1 mb.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):1062-72.
2005: Zhiwei Xu; Biyan Duan; Byron P Croker; Edward K Wakeland; Laurence Morel
Genetic dissection of the murine lupus susceptibility locus Sle2: contributions to increased peritoneal B-1a cells and lupus nephritis map to different loci.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):936-43.
2005: Jiankun Zhu; Xuebin Liu; Chun Xie; Mei Yan; Ying Yu; Eric S Sobel; Edward K Wakeland; Chandra Mohan
T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells.
The Journal of clinical investigation 2005;115(7):1869-78.
2005: Lisa A Pitcher; Meredith A Mathis; Srividya Subramanian; Jennifer A Young; Edward K Wakeland; Paul E Love; Nicolai S C van Oers
Selective expression of the 21-kilodalton tyrosine-phosphorylated form of TCR zeta promotes the emergence of T cells with autoreactive potential.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6071-9.
2005: Kui Liu; Chaoying Liang; Zhiyan Liang; Katalin Tus; Edward K Wakeland
Sle1ab mediates the aberrant activation of STAT3 and Ras-ERK signaling pathways in B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1630-7.
2005: Srividya Subramanian; Edward K Wakeland
The importance of epistatic interactions in the development of autoimmunity.
Novartis Foundation symposium 2005;267():76-88; discussion 88-93.
2005: Laura I Rutitzky; Hector J Hernandez; Young-Sun Yim; David E Ricklan; Eduardo Finger; Chandra Mohan; Inga Peter; Edward K Wakeland; Miguel J Stadecker
Enhanced egg-induced immunopathology correlates with high IFN-gamma in murine schistosomiasis: identification of two epistatic genetic intervals.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):435-40.
2004: Amy E Wandstrat; Charles Nguyen; Nisha Limaye; Alice Y Chan; Srividya Subramanian; Xiang-Hong Tian; Young-Sun Yim; Alexander Pertsemlidis; Harold R Garner; Laurence Morel; Edward K Wakeland
Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus.
Immunity 2004;21(6):769-80.
2003: Feng Zhang; Zhiyan Liang; Naoto Matsuki; Luc Van Kaer; Sebastian JOYCE; Edward K Wakeland; Thomas M Aune
A murine locus on chromosome 18 controls NKT cell homeostasis and Th cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4613-20.
2003: Michele A Kelly; Malcolm J Low; Tamara J Phillips; Edward K Wakeland; Masashi Yanagisawa
The mapping of quantitative trait loci underlying strain differences in locomotor activity between 129S6 and C57BL/6J mice.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(10):692-702.
2003: Jochen Brich; Feng-Shiun Shie; Brian Howell; Renhua Li; Katalin Tus; Edward K Wakeland; Lee-Way Jin; Marc C Mumby; Gary Churchill; Joachim Herz; Jonathan A Cooper
Genetic modulation of tau phosphorylation in the mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(1):187-92.
2002: Eric S Sobel; Laurence Morel; Raquel Baert; Chandra Mohan; Joel Schiffenbauer; Edward K Wakeland
Genetic dissection of systemic lupus erythematosus pathogenesis: evidence for functional expression of Sle3/5 by non-T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):4025-32.
2002: Edward K Wakeland; Amy E Wandstrat
Analyzing genomes: current realities and future possibilities.
Current opinion in immunology 2002;14(5):622-6.
2002: Eric S Sobel; Minoru Satoh; Yifang Chen; Edward K Wakeland; Laurence Morel
The major murine systemic lupus erythematosus susceptibility locus Sle1 results in abnormal functions of both B and T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2694-700.
2002: Silvia Bolland; Young-Sun Yim; Katalin Tus; Edward K Wakeland; Jeffrey V Ravetch
Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice.
The Journal of experimental medicine 2002;195(9):1167-74.
2002: C Myrick; R DiGuisto; J DeWolfe; E Bowen; J Kappler; P Marrack; Edward K Wakeland
Linkage analysis of variations in CD4:CD8 T cell subsets between C57BL/6 and DBA/2.
Genes and immunity 2002;3(3):144-50.
2002: Charles Nguyen; Nisha Limaye; Edward K Wakeland
Susceptibility genes in the pathogenesis of murine lupus.
Arthritis research 2002;4 Suppl 3():S255-63.
2001: Susan A Boackle; V Michael Holers; Xiaojiang S Chen; Gerda Szakonyi; David R Karp; Edward K Wakeland; Laurence Morel
Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein.
Immunity 2001;15(5):775-85.
2001: Edward K Wakeland; K Liu; Robert R Graham; timothy wayne behrens
Delineating the genetic basis of systemic lupus erythematosus.
Immunity 2001;15(3):397-408.
2001: Young-Sun Yim; Edward K Wakeland
The genetics of lupus.
Current opinion in nephrology and hypertension 2001;10(3):437-43.
2001: Laurence Morel; Kim R M Blenman; Byron P Croker; Edward K Wakeland
The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1787-92.
2000: Laurence Morel; Byron P Croker; Kim R M Blenman; Chandra Mohan; G Huang; Gary S Gilkeson; Edward K Wakeland
Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6670-5.
2000: Laurence Morel; Edward K Wakeland
Lessons from the NZM2410 model and related strains.
International reviews of immunology 2000;19(4-5):423-46.
1999: Edward K Wakeland; Amy E Wandstrat; K Liu; Laurence Morel
Genetic dissection of systemic lupus erythematosus.
Current opinion in immunology 1999;11(6):701-7.
1999: Laurence Morel; Xiang-Hong Tian; Byron P Croker; Edward K Wakeland
Epistatic modifiers of autoimmunity in a murine model of lupus nephritis.
Immunity 1999;11(2):131-9.
1999: Chandra Mohan; Laurence Morel; P Yang; H Watanabe; Byron P Croker; Gary S Gilkeson; Edward K Wakeland
Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies.
The Journal of clinical investigation 1999;103(12):1685-95.
1999: Chandra Mohan; Y Yu; Laurence Morel; P Yang; Edward K Wakeland
Genetic dissection of Sle pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation, and cell death.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6492-502.
1999: Eric S Sobel; Chandra Mohan; Laurence Morel; Joel Schiffenbauer; Edward K Wakeland
Genetic dissection of SLE pathogenesis: adoptive transfer of Sle1 mediates the loss of tolerance by bone marrow-derived B cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):2415-21.
1999: Laurence Morel; Chandra Mohan; Y Yu; Joel Schiffenbauer; U H Rudofsky; N Tian; J A Longmate; Edward K Wakeland
Multiplex inheritance of component phenotypes in a murine model of lupus.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(2):176-81.
1998: Laurence Morel; Edward K Wakeland
Susceptibility to lupus nephritis in the NZB/W model system.
Current opinion in immunology 1998;10(6):718-25.
1998: Chandra Mohan; Laurence Morel; P Yang; Edward K Wakeland
Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice.
Arthritis and rheumatism 1998;41(9):1652-62.
1998: Chandra Mohan; E Alas; Laurence Morel; P Yang; Edward K Wakeland
Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes.
The Journal of clinical investigation 1998;101(6):1362-72.
1998: C Myrick; Edward K Wakeland
Encyclopedia of the mouse genome VII. Mouse chromosome 3.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;8 Spec No():S50-67.
1997: Edward K Wakeland; Laurence Morel; K Achey; MA Yui; J Longmate
Speed congenics: a classic technique in the fast lane (relatively speaking).
Immunology today 1997;18(10):472-7.
1997: Edward K Wakeland; Laurence Morel; Chandra Mohan; MA Yui
Genetic dissection of lupus nephritis in murine models of SLE.
Journal of clinical immunology 1997;17(4):272-81.
1997: Chandra Mohan; Laurence Morel; P Yang; Edward K Wakeland
Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):454-65.
1997: Laurence Morel; Chandra Mohan; Y Yu; Byron P Croker; N Tian; A Deng; Edward K Wakeland
Functional dissection of systemic lupus erythematosus using congenic mouse strains.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):6019-28.
1997: Velizar T Tchernev; MD Barbosa; John C Detter; T D Patel; K Achey; Edward K Wakeland; Ralitza Gueorguieva; M C Yang; A Gossler; Stephen Kingsmore
Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering.
Genomics 1997;40(1):170-4.
1997: MA Yui; Edward K Wakeland
Mouse chromosome 3.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;7 Spec No():S45-59.
1996: Timothy J Vyse; Laurence Morel; F J Tanner; Edward K Wakeland; Brian L Kotzin
Backcross analysis of genes linked to autoantibody production in New Zealand White mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(6):2719-27.
1996: J Wu; J A Longmate; Grazyna Adamus; Paul A Hargrave; Edward K Wakeland
Interval mapping of quantitative trait loci controlling humoral immunity to exogenous antigens: evidence that non-MHC immune response genes may also influence susceptibility to autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(6):2498-505.
1996: M A Yui; K Muralidharan; B Moreno-Altamirano; G Perrin; K Chestnut; Edward K Wakeland
Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: an approach for the genetic dissection of complex traits.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(5):331-4.
1996: Laurence Morel; Y Yu; K R Blenman; R A Caldwell; Edward K Wakeland
Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(5):335-9.
1996: M D Barbosa; Edward K Wakeland; M Zerial; Stephen Kingsmore
Genetic mapping of the Rab5a and Rab5b genes on mouse Chromosomes 17 and 2, respectively.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(2):166-7.
1996: Edward K Wakeland; Michael F Seldin
Encyclopedia of the mouse genome V. Mouse chromosome 3.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;6 Spec No():S64-72.
1996: C C Lu; Y Ye; Jin-Xiong She; François Bonhomme; Edward K Wakeland
Evolutionary origins of retroposon lineages of Mhc class II Ab alleles.
Immunogenetics 1996;43(3):115-24.
1995: Scott V Edwards; Edward K Wakeland; W K Potts
Contrasting histories of avian and mammalian Mhc genes revealed by class II B sequences from songbirds.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12200-4.
1995: M D Barbosa; S A Johnson; K Achey; M J Gutierrez; Edward K Wakeland; M Zerial; Stephen Kingsmore
The Rab protein family: genetic mapping of six Rab genes in the mouse.
Genomics 1995;30(3):439-44.
1995: M D Barbosa; S A Johnson; K Achey; M J Gutierrez; Edward K Wakeland; Stephen Kingsmore
Genetic mapping of the choroideremia-like, rab escort protein-2 gene on mouse chromosome 1.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(7):488-9.
1994: W K Potts; C J Manning; Edward K Wakeland
The role of infectious disease, inbreeding and mating preferences in maintaining MHC genetic diversity: an experimental test.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994;346(1317):369-78.
1994: Laurence Morel; U H Rudofsky; J A Longmate; Joel Schiffenbauer; Edward K Wakeland
Polygenic control of susceptibility to murine systemic lupus erythematosus.
Immunity 1994;1(3):219-29.
1994: Jin-Xiong She; L P Zhang; J Scornik; Edward K Wakeland
Nucleotide sequence of a novel HLA-DRB1 allele, DRB1*0810 [corrected].
Immunogenetics 1994;39(1):78.
1994: Jin-Xiong She; M M Bui; X H Tian; Andrew Muir; Edward K Wakeland; B Zorovich; L P Zhang; M C Liu; G Thomson; Noel Maclaren
Additive susceptibility to insulin-dependent diabetes conferred by HLA-DQB1 and insulin genes.
Autoimmunity 1994;18(3):195-203.
1993: W K Potts; Edward K Wakeland
Evolution of MHC genetic diversity: a tale of incest, pestilence and sexual preference.
Trends in genetics : TIG 1993;9(12):408-12.
1993: K Muralidharan; Edward K Wakeland
Concentration of primer and template qualitatively affects products in random-amplified polymorphic DNA PCR.
BioTechniques 1993;14(3):362-4.
1993: Kye A Chesnut; Jin-Xiong She; I Cheng; K Muralidharan; Edward K Wakeland
Characterizations of candidate genes for IDD susceptibility from the diabetes-prone NOD mouse strain.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(10):549-54.
1992: C J Manning; Edward K Wakeland; W K Potts
Communal nesting patterns in mice implicate MHC genes in kin recognition.
Nature 1992;360(6404):581-3.
1992: William E Winter; K Yamada; K Shimpo; R Luchetta; Edward K Wakeland
T cell receptor beta diversity and joining segments in the NOD mouse.
Autoimmunity 1992;12(1):9-12.
1991: W K Potts; C J Manning; Edward K Wakeland
Mating patterns in seminatural populations of mice influenced by MHC genotype.
Nature 1991;352(6336):619-21.
1991: K R Horlick; I C Cheng; W T Wong; Edward K Wakeland; Harry S Nick
Mouse lipocortin I gene structure and chromosomal assignment: gene duplication and the origins of a gene family.
Genomics 1991;10(2):365-74.
1991: Jin-Xiong She; S A Boehme; T W Wang; François Bonhomme; Edward K Wakeland
Amplification of major histocompatibility complex class II gene diversity by intraexonic recombination.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):453-7.
1990: Wayne K Potts; Edward K Wakeland
Evolution of diversity at the major histocompatibility complex.
Trends in ecology & evolution 1990;5(6):181-7.
1990: W K Potts; Edward K Wakeland
The maintenance of MHC polymorphism.
Immunology today 1990;11(2):39-40.
1990: Edward K Wakeland; S Boehme; Jin-Xiong She
The generation and maintenance of MHC class II gene polymorphism in rodents.
Immunological reviews 1990;113():207-26.
1990: Edward K Wakeland; S Boehme; Jin-Xiong She; C C Lu; McIndoe Richard; I Cheng; Y Ye; W K Potts
Ancestral polymorphisms of MHC class II genes: divergent allele advantage.
Immunologic research 1990;9(2):115-22.
1988: T J McConnell; W S Talbot; McIndoe Richard; Edward K Wakeland
The origin of MHC class II gene polymorphism within the genus Mus.
Nature 1988;332(6165):651-4.
1987: András Falus; Edward K Wakeland; T J McConnell; J Gitlin; A S Whitehead; H R Colten
DNA polymorphism of MHC III genes in inbred and wild mouse strains.
Immunogenetics 1987;25(5):290-8.
1986: T J McConnell; B Darby; Edward K Wakeland
Restriction fragment-length polymorphisms of class II gene sequences in mice expressing minor structural variants of I-Ak and I-Ap.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(8):3076-84.
1986: Edward K Wakeland; McIndoe Richard; T J McConnell
Genetic diversity of class II genes in wild mice: definition of five evolutionary groups by RFLP analysis of A alpha and A beta.
Current topics in microbiology and immunology 1986;127():255-60.
1985: Edward K Wakeland; B Darby; J E Coligan
Localization of structural variations distinguishing I-Ak-related molecules to the alpha 1 and beta 1 domains.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(1):391-8.
1983: A B Peck; B Darby; Edward K Wakeland
Variant class II molecules from H-2 haplotypes in wild mouse populations: functional characteristics of closely related class II gene products.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(5):2432-9.