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Jean-Michel Wal

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Stéphanie Morin; Laetitia Przybylski-Nicaise; Sylvie Rabot; Jean-Michel Wal; Hervé Bernard; Gérard Corthier; Romy Fischer; Stéphane Hazebrouck
Delayed bacterial colonization of the gut alters the host immune response to oral sensitization against cow's milk proteins.
Karine Adel-Patient; Sandrine Ah-Leung; Hervé Bernard; Rodolphe Fritsché; Annick Mercenier; Narimane Meziti; Sophie Nutten; Guénolée Prioult; Jean-Michel Wal
Immunomodulatory potential of partially hydrolyzed β-lactoglobulin and large synthetic peptides.
Hervé Bernard; E Bidat; Marie-Françoise Drumare; Evelyne Paty; Sylvain Tilleul; Jean-Michel Wal; Sandrine Ah-Leung; Stéphane Hazebrouck
Specificity of IgE antibodies from patients allergic to goat's milk and tolerant to cow's milk determined with plasmin-derived peptides of bovine and caprine β-caseins.

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2012: Stéphanie Morin; Laetitia Przybylski-Nicaise; Sylvie Rabot; Jean-Michel Wal; Hervé Bernard; Gérard Corthier; Romy Fischer; Stéphane Hazebrouck
Delayed bacterial colonization of the gut alters the host immune response to oral sensitization against cow's milk proteins.
Molecular nutrition & food research 2012;56(12):1838-47.
2012: Karine Adel-Patient; Sandrine Ah-Leung; Hervé Bernard; Rodolphe Fritsché; Annick Mercenier; Narimane Meziti; Sophie Nutten; Guénolée Prioult; Jean-Michel Wal
Immunomodulatory potential of partially hydrolyzed β-lactoglobulin and large synthetic peptides.
Journal of agricultural and food chemistry 2012;60(43):10858-66.
2012: Hervé Bernard; E Bidat; Marie-Françoise Drumare; Evelyne Paty; Sylvain Tilleul; Jean-Michel Wal; Sandrine Ah-Leung; Stéphane Hazebrouck
Specificity of IgE antibodies from patients allergic to goat's milk and tolerant to cow's milk determined with plasmin-derived peptides of bovine and caprine β-caseins.
Molecular nutrition & food research 2012;56(10):1532-40.
2012: Stéphane Hazebrouck; Evelyne Paty; Jean-Michel Wal; Marie-Françoise Drumare; Blanche Guillon; Hervé Bernard
Trypsin resistance of the major peanut allergen Ara h 6 and allergenicity of the digestion products are abolished after selective disruption of disulfide bonds.
Molecular nutrition & food research 2012;56(4):548-57.
2011: Fany Blanc; A Patrick Gunning; Ad P H Jansen; Alan R Mackie; Karine Adel-Patient; Barbara K Ballmer-Weber; Hervé Bernard; Laetitia Przybylski-Nicaise; Neil M Rigby; Janneke Ruinemans-Koerts; Huub F J Savelkoul; Per S Skov; Zsolt Szépfalusi; Yvonne M Vissers; Jean-Michel Wal; Nikolaus K Wellner; Harry J Wichers; Laurian Zuidmeer-Jongejan; E N Clare Mills
Boiling peanut Ara h 1 results in the formation of aggregates with reduced allergenicity.
Molecular nutrition & food research 2011;55(12):1887-94.
2011: Stéphanie Morin; Laetitia Przybylski-Nicaise; Sylvie Rabot; Jean-Michel Wal; Hervé Bernard; Gérard Corthier; Stéphane Hazebrouck
Allergenic and immunogenic potential of cow's milk β-lactoglobulin and caseins evidenced without adjuvant in germ-free mice.
Molecular nutrition & food research 2011;55(11):1700-7.
2011: Karine Adel-Patient; Sandrine Ah-Leung; Hervé Bernard; N Meziti; S Wavrin; Jean-Michel Wal
Oral tolerance and Treg cells are induced in BALB/c mice after gavage with bovine β-lactoglobulin.
Allergy 2011;66(10):1312-21.
2011: Apostolos Bossios; Clare En Mills; Lucie Mondoulet; Nikolaos G Papadopoulos; Karine Adel-Patient; Hervé Bernard; Neil M Rigby; Maria Theodoropoulou; Jean-Michel Wal; Photini Papageorgiou
Effect of simulated gastro-duodenal digestion on the allergenic reactivity of beta-lactoglobulin.
Clinical and translational allergy 2011;1(1):6.
2011: Karine Adel-Patient; Valeria D Guimaraes; Alain Paris; Marie-Françoise Drumare; Sandrine Ah-Leung; Patricia Lamourette; Marie-Claire Nevers; Cécile Canlet; Jérôme Molina; Hervé Bernard; Christophe Créminon; Jean-Michel Wal
Immunological and metabolomic impacts of administration of Cry1Ab protein and MON 810 maize in mouse.
PloS one 2011;6(1):e16346.
2010: P Poncet; H Senechal; G Clement; A Purohit; J-P Sutra; François-Xavier Desvaux; Jean-Michel Wal; G Pauli; Gabriel Peltre; M-L Gougeon
Evaluation of ash pollen sensitization pattern using proteomic approach with individual sera from allergic patients.
Allergy 2010;65(5):571-80.
2010: Valeria Guimaraes; Marie-Françoise Drumare; Didier Lereclus; Michel Gohar; Patricia Lamourette; Marie-Claire Nevers; Marie-Lisa Vaisanen-Tunkelrott; Hervé Bernard; Blanche Guillon; Christophe Créminon; Jean-Michel Wal; Karine Adel-Patient
In vitro digestion of Cry1Ab proteins and analysis of the impact on their immunoreactivity.
Journal of agricultural and food chemistry 2010;58(5):3222-31.
2010: Karine Adel-Patient; Laetitia Pothelune; Sandrine Ah-Leung; Jean-Michel Wal; Christophe Créminon; Jean-Marc Chatel
Block copolymers have differing adjuvant effects on the primary immune response elicited by genetic immunization and on further induced allergy.
Clinical and vaccine immunology : CVI 2010;17(1):36-42.
2009: S Hazebrouck; L Przybylski-Nicaise; Sandrine Ah-Leung; Karine Adel-Patient; Gérard Corthier; Philippe Langella; Jean-Michel Wal
Influence of the route of administration on immunomodulatory properties of bovine beta-lactoglobulin-producing Lactobacillus casei.
Vaccine 2009;27(42):5800-5.
2009: Hervé Bernard; Marie-Françoise Drumare; Blanche Guillon; Evelyne Paty; Pierre Scheinmann; Jean-Michel Wal
Immunochemical characterisation of structure and allergenicity of peanut 2S albumins using different formats of immunoassays.
Analytical and bioanalytical chemistry 2009;395(1):139-46.
2009: Naima Cortes-Perez; Sandrine Ah-Leung; Luis G Bermúdez-Humarán; Gérard Corthier; Philippe Langella; Jean-Michel Wal; Karine Adel-Patient
Allergy therapy by intranasal administration with recombinant Lactococcus lactis Producing bovine beta-lactoglobulin.
International archives of allergy and immunology 2009;150(1):25-31.
2007: Hervé Bernard; Lucie Mondoulet; Marie-Françoise Drumare; Evelyne Paty; Pierre Scheinmann; R Thaï; Jean-Michel Wal
Identification of a new natural Ara h 6 isoform and of its proteolytic product as major allergens in peanut.
Journal of agricultural and food chemistry 2007;55(23):9663-9.
2007: Naima Cortes-Perez; Sandrine Ah-Leung; Luis G Bermúdez-Humarán; Gérard Corthier; Jean-Michel Wal; Philippe Langella; Karine Adel-Patient
Intranasal coadministration of live lactococci producing interleukin-12 and a major cow's milk allergen inhibits allergic reaction in mice.
Clinical and vaccine immunology : CVI 2007;14(3):226-33.
2007: Rainer Hartmann; Jean-Michel Wal; Hervé Bernard; Anne-Kathrin Pentzien
Cytotoxic and allergenic potential of bioactive proteins and peptides.
Current pharmaceutical design 2007;13(9):897-920.
2007: Stéphane Hazebrouck; Laetitia Pothelune; Vasco Azevedo; Gérard Corthier; Jean-Michel Wal; Philippe Langella
Efficient production and secretion of bovine beta-lactoglobulin by Lactobacillus casei.
Microbial cell factories 2007;6():12.
2007: Riccardo Asero; Barbara K Ballmer-Weber; Kirsten Beyer; Amedeo Conti; Ruta Dubakiene; Montserrat Fernandez Rivas; Karin Hoffmann-Sommergruber; Jonas Lidholm; Tihomir Mustakov; Joanne N G Oude Elberink; Richard S H Pumphrey; Per Stahl Skov; Ronald van Ree; Berber J Vlieg-Boerstra; Reinhard Hiller; J O'B Hourihane; Marek Kowalski; Nikolaos Papadopoulos; Jean-Michel Wal; E N Clare Mills; Stefan Vieths
IgE-mediated food allergy diagnosis: Current status and new perspectives.
Molecular nutrition & food research 2007;51(1):135-47.
2007: Karine Adel-Patient; Sandrine Ah-Leung; Hervé Bernard; Coralie Durieux-Alexandrenne; Christophe Créminon; Jean-Michel Wal
Oral sensitization to peanut is highly enhanced by application of peanut extracts to intact skin, but is prevented when CpG and cholera toxin are added.
International archives of allergy and immunology 2007;143(1):10-20.
2006: S Hazebrouck; Raish Oozeer; Karine Adel-Patient; Philippe Langella; Sylvie Rabot; Jean-Michel Wal; Gérard Corthier
Constitutive delivery of bovine beta-lactoglobulin to the digestive tracts of gnotobiotic mice by engineered Lactobacillus casei.
Applied and environmental microbiology 2006;72(12):7460-7.
2006: Sandrine Ah-Leung; Hervé Bernard; E Bidat; Evelyne Paty; F Rancé; Pierre Scheinmann; Jean-Michel Wal
Allergy to goat and sheep milk without allergy to cow's milk.
Allergy 2006;61(11):1358-65.
2006: Valéria Dellaretti Guimarães; Silvia Innocentin; François Lefèvre; Vasco Azevedo; Jean-Michel Wal; Philippe Langella; Jean-Marc Chatel
Use of native lactococci as vehicles for delivery of DNA into mammalian epithelial cells.
Applied and environmental microbiology 2006;72(11):7091-7.
2006: Thomas Eiwegger; Neil M Rigby; Lucie Mondoulet; Hervé Bernard; Maria-Theresa Krauth; A Boehm; Eleonora Dehlink; Peter Valent; Jean-Michel Wal; E N Clare Mills; Zsolt Szépfalusi
Gastro-duodenal digestion products of the major peanut allergen Ara h 1 retain an allergenic potential.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(10):1281-8.
2006: Françoise Guéraud; Géraldine Peiro; Hervé Bernard; Jacques Alary; Christophe Créminon; Laurent Debrauwer; Estelle Rathahao; Marie-Françoise Drumare; Cécile Canlet; Jean-Michel Wal; Georges Bories
Enzyme immunoassay for a urinary metabolite of 4-hydroxynonenal as a marker of lipid peroxidation.
Free radical biology & medicine 2006;40(1):54-62.
2005: Rodolphe Fritsché; Karine Adel-Patient; Hervé Bernard; Christine Martin-Paschoud; Catherine Schwarz; Sandrine Ah-Leung; Jean-Michel Wal
IgE-mediated rat mast cell triggering with tryptic and synthetic peptides of bovine beta-lactoglobulin.
International archives of allergy and immunology 2005;138(4):291-7.
2005: Gilles Clement; Didier Boquet; Lucie Mondoulet; Patricia Lamourette; Hervé Bernard; Jean-Michel Wal
Expression in Escherichia coli and disulfide bridge mapping of PSC33, an allergenic 2S albumin from peanut.
Protein expression and purification 2005;44(2):110-20.
2005: Lucie Mondoulet; Evelyne Paty; Marie-Françoise Drumare; Sandrine Ah-Leung; Pierre Scheinmann; R M Willemot; Jean-Michel Wal; Hervé Bernard
Influence of thermal processing on the allergenicity of peanut proteins.
Journal of agricultural and food chemistry 2005;53(11):4547-53.
2005: Karine Adel-Patient; Hervé Bernard; Sandrine Ah-Leung; Christophe Créminon; Jean-Michel Wal
Peanut- and cow's milk-specific IgE, Th2 cells and local anaphylactic reaction are induced in Balb/c mice orally sensitized with cholera toxin.
Allergy 2005;60(5):658-64.
2005: Karine Adel-Patient; Sandrine Ah-Leung; Christophe Creminon; Sébastien Nouaille; Jean-Marc Chatel; Philippe Langella; Jean-Michel Wal
Oral administration of recombinant Lactococcus lactis expressing bovine beta-lactoglobulin partially prevents mice from sensitization.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(4):539-46.
2005: Sébastien Nouaille; Luis G Bermúdez-Humarán; Karine Adel-Patient; Jacqueline Commissaire; Alexandra Gruss; Jean-Michel Wal; Vasco Azevedo; Philippe Langella; Jean-Marc Chatel
Improvement of bovine beta-lactoglobulin production and secretion by Lactococcus lactis.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2005;38(3):353-9.
2004: Jean-Michel Wal
Bovine milk allergenicity.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(5 Suppl 3):S2-11.
2004: Daniel J Walsh; Hervé Bernard; Brian A Murray; J MacDonald; A-K Pentzien; G A Wright; Jean-Michel Wal; A D Struthers; H Meisel; Richard J FitzGerald
In vitro generation and stability of the lactokinin beta-lactoglobulin fragment (142-148).
Journal of dairy science 2004;87(11):3845-57.
2004: Karine Adel-Patient; Jean-Michel Wal
[Animal models for assessment of GMO allergenicity: advantages and limitations].
European annals of allergy and clinical immunology 2004;36(3):88-91.
2003: Hervé Bernard; Evelyne Paty; Lucie Mondoulet; A Wesley Burks; G A Bannon; Jean-Michel Wal; Pierre Scheinmann
Serological characteristics of peanut allergy in children.
Allergy 2003;58(12):1285-92.
2003: Jean-Marc Chatel; Sébastien Nouaille; Karine Adel-Patient; Yves Le Loir; Herman Boe; Alexandra Gruss; Jean-Michel Wal; Philippe Langella
Characterization of a Lactococcus lactis strain that secretes a major epitope of bovine beta-lactoglobulin and evaluation of its immunogenicity in mice.
Applied and environmental microbiology 2003;69(11):6620-7.
2003: Hélène Chardin; CE Mayer; Hélène Sénéchal; Jean-Michel Wal; P Poncet; François-Xavier Desvaux; Gabriel Peltre
Lipid transfer protein 1 is a possible allergen in Arabidopsis thaliana.
International archives of allergy and immunology 2003;131(2):85-90.
2003: Hélène Chardin; CE Mayer; Hélène Sénéchal; P Poncet; G Clément; Jean-Michel Wal; François-Xavier Desvaux; Gabriel Peltre
Polygalacturonase (pectinase), a new oilseed rape allergen.
Allergy 2003;58(5):407-11.
2003: H Meisel; Hervé Bernard; Susan J Fairweather-Tait; Richard J FitzGerald; Rainer Hartmann; C N Lane; David McDonagh; Birgit Teucher; Jean-Michel Wal
Detection of caseinophosphopeptides in the distal ileostomy fluid of human subjects.
The British journal of nutrition 2003;89(3):351-9.
2003: Karine Adel-Patient; Marie-Anne Nahori; Barbara Proust; José Roberto Lapa e Silva; Christophe Créminon; Jean-Michel Wal; B Boris Vargaftig
Elicitation of the allergic reaction in beta-lactoglobulin-sensitized Balb/c mice: biochemical and clinical manifestations differ according to the structure of the allergen used for challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(3):376-85.
2002: Jean-Michel Wal
Cow's milk proteins/allergens.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2002;89(6 Suppl 1):3-10.
2002: Gilles Clement; Didier Boquet; Yveline Frobert; Hervé Bernard; Luc Negroni; Jean-Marc Chatel; Karine Adel-Patient; Christophe Creminon; Jean-Michel Wal; Jacques Grassi
Epitopic characterization of native bovine beta-lactoglobulin.
Journal of immunological methods 2002;266(1-2):67-78.
2002: Karine Adel-Patient; Ch Créminon; Didier Boquet; Jean-Michel Wal; Jean-Marc Chatel
[Prevention of an IgE response to bovine beta-lactoglobulin by gene immunization in mice].
Allergie et immunologie 2002;34(3):77-81.
2001: Karine Adel-Patient; Christophe Creminon; Didier Boquet; Jean-Michel Wal; Jean-Marc Chatel
Genetic immunisation with bovine beta-lactoglobulin cDNA induces a preventive and persistent inhibition of specific anti-BLG IgE response in mice.
International archives of allergy and immunology 2001;126(1):59-67.
2001: H Meisel; Hervé Bernard; Susan J Fairweather-Tait; Richard J FitzGerald; Rainer Hartmann; C N Lane; David McDonagh; Birgit Teucher; Jean-Michel Wal
Nutraceutical and functional food ingredients for food and pharmaceutical applications.
The British journal of nutrition 2001;85(5):635.
2001: Jean-Marc Chatel; Philippe Langella; Karine Adel-Patient; Jacqueline Commissaire; Jean-Michel Wal; Gérard Corthier
Induction of mucosal immune response after intranasal or oral inoculation of mice with Lactococcus lactis producing bovine beta-lactoglobulin.
Clinical and diagnostic laboratory immunology 2001;8(3):545-51.
2000: Karine Adel-Patient; Christophe Créminon; Hervé Bernard; G Clément; L Négroni; Yveline Frobert; Jacques Grassi; Jean-Michel Wal; Jean-Marc Chatel
Evaluation of a high IgE-responder mouse model of allergy to bovine beta-lactoglobulin (BLG): development of sandwich immunoassays for total and allergen-specific IgE, IgG1 and IgG2a in BLG-sensitized mice.
Journal of immunological methods 2000;235(1-2):21-32.
2000: Hervé Bernard; H Meisel; Christophe Creminon; Jean-Michel Wal
Post-translational phosphorylation affects the IgE binding capacity of caseins.
FEBS letters 2000;467(2-3):239-44.
2000: Hervé Bernard; Luc Negroni; Jean-Marc Chatel; Gilles Clement; Karine Adel-Patient; Gabriel Peltre; Christophe Creminon; Jean-Michel Wal
Molecular basis of IgE cross-reactivity between human beta-casein and bovine beta-casein, a major allergen of milk.
Molecular immunology 2000;37(3-4):161-7.
1999: Isabelle Sélo; G Clément; Hervé Bernard; Jean-Marc Chatel; Christophe Créminon; Gabriel Peltre; Jean-Michel Wal
Allergy to bovine beta-lactoglobulin: specificity of human IgE to tryptic peptides.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(8):1055-63.
1999: Jean-Marc Chatel; Karine Adel-Patient; Christophe Créminon; Jean-Michel Wal
Expression of a lipocalin in prokaryote and eukaryote cells: quantification and structural characterization of recombinant bovine beta-lactoglobulin.
Protein expression and purification 1999;16(1):70-5.
1998: Luc Negroni; Hervé Bernard; Gilles Clement; Jean-Marc Chatel; P Brune; Yveline Frobert; Jean-Michel Wal; Jacques Grassi
Two-site enzyme immunometric assays for determination of native and denatured beta-lactoglobulin.
Journal of immunological methods 1998;220(1-2):25-37.
1998: Isabelle Sélo; L Négroni; Christophe Créminon; M Yvon; Gabriel Peltre; Jean-Michel Wal
Allergy to bovine beta-lactoglobulin: specificity of human IgE using cyanogen bromide-derived peptides.
International archives of allergy and immunology 1998;117(1):20-8.
1998: H Bernard; C Créminon; M Yvon; Jean-Michel Wal
Specificity of the human IgE response to the different purified caseins in allergy to cow's milk proteins.
International archives of allergy and immunology 1998;115(3):235-44.
1997: G S Matthews; K Miller; Christophe Creminon; Jean-Michel Wal
An enzyme-linked immunosorbent assay for the detection of antigen-specific rat immunoglobulin E with improved sensitivity upon a conventional horseradish peroxidase-based ELISA method.
Biochemical Society transactions 1997;25(2):375S.
1996: I Sélo; L Négroni; Christophe Créminon; Jacques Grassi; Jean-Michel Wal
Preferential labeling of alpha-amino N-terminal groups in peptides by biotin: application to the detection of specific anti-peptide antibodies by enzyme immunoassays.
Journal of immunological methods 1996;199(2):127-38.
1996: Jean-Marc Chatel; Hervé Bernard; Gilles Clement; Yveline Frobert; Carl A Batt; J Gavalchin; G Peltres; Jean-Michel Wal
Expression, purification and immunochemical characterization of recombinant bovine beta-lactoglobulin, a major cow milk allergen.
Molecular immunology 1996;33(14):1113-8.
1996: C Lefranc-Millot; D Vercaigne-Marko; Jean-Michel Wal; A Leprêtre; Gabriel Peltre; P Dhulster; Didier Guillochon
Comparison of the IgE titers to bovine colostral G immunoglobulins and their F(ab')2 fragments in sera of patients allergic to milk.
International archives of allergy and immunology 1996;110(2):156-62.
1995: Jean-Michel Wal; Hervé Bernard; Christophe Créminon; C Hamberger; B David; Gabriel Peltre
Cow's milk allergy: the humoral immune response to eight purified allergens.
Advances in experimental medicine and biology 1995;371B():879-81.
1995: V Brodard; Hervé Bernard; Jean-Michel Wal; B David; Gabriel Peltre
Two-dimensional analysis of cow's milk allergens with the IPG-DALT technique.
Advances in experimental medicine and biology 1995;371B():875-8.
1994: G Clément; R Christon; Christophe Créminon; Yveline Frobert; Philippe Pradelles; Jean-Michel Wal
Essential fatty acid deficiency in the pig: effects on eicosanoid basal levels and in vitro synthesis by the small intestine.
Prostaglandins, leukotrienes, and essential fatty acids 1994;50(3):147-54.
1991: M Yvon; Jean-Michel Wal
Tandem immunoaffinity and reversed-phase high-performance liquid chromatography for the identification of the specific binding sites of a hapten on a proteic carrier.
Journal of chromatography 1991;539(2):363-71.
1991: Jean-Michel Wal; M Yvon; P Pradelles; Jacques Grassi
Enzyme immunoassay of benzyl penicilloyl (BPO) groups using acetylcholinesterase as label. Application to the study of the BPO-binding sites on albumin.
Journal of immunoassay 1991;12(1):47-64.
1990: M Yvon; P Anglade; Jean-Michel Wal
Identification of the binding sites of benzyl penicilloyl, the allergenic metabolite of penicillin, on the serum albumin molecule.
FEBS letters 1990;263(2):237-40.
1989: M Yvon; P Anglade; Jean-Michel Wal
Binding of benzyl penicilloyl to human serum albumin. Evidence for a highly reactive region at the junction of domains 1 and 2 of the albumin molecule.
FEBS letters 1989;247(2):273-8.
1988: R Perez-Ruiz; Jean-Michel Wal; O Szylit
Histamine distribution in the gastrointestinal wall of germ free and conventional chicken: evidence of the role of the digestive microflora.
Agents and actions 1988;25(3-4):273-6.
1988: M Yvon; Jean-Michel Wal
Identification of lysine residue 199 of human serum albumin as a binding site for benzylpenicilloyl groups.
FEBS letters 1988;239(2):237-40.