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Claire Walczak

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Lesley N Weaver; Stephanie C Ems-McClung; Melissa K Gardner; Chantal LeBlanc; Sidney L Shaw; Jane R Stout; Claire E Walczak
Kif18A uses a microtubule binding site in the tail for plus-end localization and spindle length regulation.
Jane R Stout; Stephanie C Ems-McClung; Chantal Leblanc; James A Powers; Amber L Yount; Claire E Walczak
Kif18B interacts with EB1 and controls astral microtubule length during mitosis.
Claire E Walczak; Sidney L Shaw
A MAP for bundling microtubules.

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All Publications

2011: Lesley N Weaver; Stephanie C Ems-McClung; Melissa K Gardner; Chantal LeBlanc; Sidney L Shaw; Jane R Stout; Claire E Walczak
Kif18A uses a microtubule binding site in the tail for plus-end localization and spindle length regulation.
Current biology : CB 2011;21(17):1500-6.
2011: Jane R Stout; Stephanie C Ems-McClung; Chantal Leblanc; James A Powers; Amber L Yount; Claire E Walczak
Kif18B interacts with EB1 and controls astral microtubule length during mitosis.
Molecular biology of the cell 2011;22(17):3070-80.
2010: Claire E Walczak; Sidney L Shaw
A MAP for bundling microtubules.
Cell 2010;142(3):364-7.
2010: Shang Cai; Lesley N Weaver; Stephanie C Ems-McClung; Claire E Walczak
Proper organization of microtubule minus ends is needed for midzone stability and cytokinesis.
Current biology : CB 2010;20(9):880-5.
2010: Stephanie C Ems-McClung; Claire E Walczak
Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules.
Seminars in cell & developmental biology 2010;21(3):276-82.
2010: Claire E Walczak; Shang Cai; Alexey Khodjakov
Mechanisms of chromosome behaviour during mitosis.
Nature reviews. Molecular cell biology 2010;11(2):91-102.
2010: Claire E Walczak; Rania S Rizk; Sidney L Shaw
The use of fluorescence redistribution after photobleaching for analysis of cellular microtubule dynamics.
Methods in cell biology 2010;97():35-52.
2009: Shang Cai; Christopher B O'Connell; Alexey Khodjakov; Claire E Walczak
Chromosome congression in the absence of kinetochore fibres.
Nature cell biology 2009;11(7):832-8.
2009: Rania S Rizk; Kevin P Bohannon; Laura A Wetzel; James Powers; Sidney L Shaw; Claire E Walczak
MCAK and paclitaxel have differential effects on spindle microtubule organization and dynamics.
Molecular biology of the cell 2009;20(6):1639-51.
2009: Shang Cai; Lesley N Weaver; Stephanie C Ems-McClung; Claire E Walczak
Kinesin-14 family proteins HSET/XCTK2 control spindle length by cross-linking and sliding microtubules.
Molecular biology of the cell 2009;20(5):1348-59.
2009: Marni Brisson Tierno; Carolyn A Kitchens; Bethany Petrik; Thomas H Graham; Peter Wipf; Fengfeng L Xu; William S Saunders; Brianne S Raccor; Raghavan Balachandran; Billy W Day; Jane R Stout; Claire E Walczak; Alexander P Ducruet; Celeste E Reese; John Lazo
Microtubule binding and disruption and induction of premature senescence by disorazole C(1).
The Journal of pharmacology and experimental therapeutics 2009;328(3):715-22.
2009: Jane R Stout; Rania S Rizk; Claire E Walczak
Protein inhibition by microinjection and RNA-mediated interference in tissue culture cells: complementary approaches to study protein function.
Methods in molecular biology (Clifton, N.J.) 2009;518():77-97.
2008: Shang Cai; Claire E Walczak
Kinetochore attachment: how the hec can a cell do it?
Current biology : CB 2008;18(23):R1093-6.
2008: Kathleen M Hertzer; Claire E Walczak
The C-termini of tubulin and the specific geometry of tubulin substrates influence the depolymerization activity of MCAK.
Cell cycle (Georgetown, Tex.) 2008;7(17):2727-37.
2008: David G Hedrick; Jane R Stout; Claire E Walczak
Effects of anti-microtubule agents on microtubule organization in cells lacking the kinesin-13 MCAK.
Cell cycle (Georgetown, Tex.) 2008;7(14):2146-56.
2008: Xin Zhang; Stephanie C Ems-McClung; Claire E Walczak
Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity.
Molecular biology of the cell 2008;19(7):2752-65.
2008: Claire E Walczak; Rebecca Heald
Mechanisms of mitotic spindle assembly and function.
International review of cytology 2008;265():111-58.
2007: Sidney L Shaw; Claire E Walczak
Spindles: one speckle at a time.
Nature cell biology 2007;9(11):1223-4.
2007: Xin Zhang; Weijie Lan; Stephanie C Ems-McClung; P Todd Stukenberg; Claire E Walczak
Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function.
Molecular biology of the cell 2007;18(9):3264-76.
2007: Claire E Walczak
Claire Walczak.
Current biology : CB 2007;17(12):R440-1.
2007: Stephanie C Ems-McClung; Kathleen M Hertzer; Xin Zhang; Mill W Miller; Claire E Walczak
The interplay of the N- and C-terminal domains of MCAK control microtubule depolymerization activity and spindle assembly.
Molecular biology of the cell 2007;18(1):282-94.
2006: Xin Zhang; Claire E Walczak
Chromosome segregation: correcting improperly attached chromosomes.
Current biology : CB 2006;16(17):R677-9.
2006: Claire E Walczak
Kinesin-8s: motoring and depolymerizing.
Nature cell biology 2006;8(9):903-5.
2006: Claire E Walczak
Parting company with the chromosome segregation and aneuploidy series.
Trends in cell biology 2006;16(2):65-6.
2006: Kathleen M Hertzer; Stephanie C Ems-McClung; Susan L. Kline; Thomas G Lipkin; Susan P Gilbert; Claire E Walczak
Full-length dimeric MCAK is a more efficient microtubule depolymerase than minimal domain monomeric MCAK.
Molecular biology of the cell 2006;17(2):700-10.
2006: Jane R Stout; Rania S Rizk; Susan L. Kline; Claire E Walczak
Deciphering protein function during mitosis in PtK cells using RNAi.
BMC cell biology 2006;7():26.
2005: Rania S Rizk; Claire E Walczak
Chromosome dynamics: actin's gone fishing.
Current biology : CB 2005;15(20):R841-2.
2005: Per Holmfeldt; Xin Zhang; Sonja Stenmark; Claire E Walczak; Martin Gullberg
CaMKIIgamma-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation.
The EMBO journal 2005;24(6):1256-66.
2005: Claire E Walczak
CLASP fluxes its mitotic muscles.
Nature cell biology 2005;7(1):5-7.
2004: Carolyn J Lawrence; R Kelly Dawe; Karen R Christie; Don W Cleveland; Scott C Dawson; Sharyn A Endow; Lawrence S B Goldstein; Holly V Goodson; Nobutaka Hirokawa; Jonathon Howard; Russell L Malmberg; J Richard McIntosh; Harukata Miki; Timothy J Mitchison; Yasushi Okada; Anireddy S N Reddy; William M Saxton; Manfred Schliwa; Jonathan M Scholey; Ronald D Vale; Claire E Walczak; Linda Wordeman
A standardized kinesin nomenclature.
The Journal of cell biology 2004;167(1):19-22.
2004: Susan L. Kline; Claire E Walczak
Mitotic spindle assembly and chromosome segregation: refocusing on microtubule dynamics.
Molecular cell 2004;15(3):317-27.
2004: Susan L. Kline; Alexey Khodjakov; Polla Hergert; Claire E Walczak
Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments.
Molecular biology of the cell 2004;15(3):1146-59.
2004: Stephanie C Ems-McClung; Claire E Walczak
Catastrophic kinesins: piecing together their mechanism by 3D reconstruction.
Cell 2004;116(4):485-6.
2004: Weijie Lan; Xin Zhang; Susan L. Kline; Sara E Rosasco; Gregory A Barrett-Wilt; Jeffrey Shabanowitz; Donald F Hunt; Claire E Walczak; P Todd Stukenberg
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity.
Current biology : CB 2004;14(4):273-86.
2004: Gregory Rogers; Stephen L Rogers; Tamara A Schwimmer; Stephanie C Ems-McClung; Claire E Walczak; Ronald D Vale; Jonathan M Scholey; David J Sharp
Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase.
Nature 2004;427(6972):364-70.
2004: Stephanie C Ems-McClung; Yixian Zheng; Claire E Walczak
Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal.
Molecular biology of the cell 2004;15(1):46-57.
2003: Sue Biggins; Claire E Walczak
Captivating capture: how microtubules attach to kinetochores.
Current biology : CB 2003;13(11):R449-60.
2003: Claire E Walczak
The Kin I kinesins are microtubule end-stimulated ATPases.
Molecular cell 2003;11(2):286-8.
2003: Kathleen M Hertzer; Stephanie C Ems-McClung; Claire E Walczak
Kin I kinesins: insights into the mechanism of depolymerization.
Critical reviews in biochemistry and molecular biology 2003;38(6):453-69.
2002: Claire E Walczak; Eugene C Gan; Arshad Desai; Timothy J Mitchison; Susan L. Kline
The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly.
Current biology : CB 2002;12(21):1885-9.
2002: Susan L. Kline; Claire E Walczak
The microtubule-destabilizing kinesin XKCM1 regulates microtubule dynamic instability in cells.
Molecular biology of the cell 2002;13(8):2718-31.
2002: Hanspeter Niederstrasser; Hani Salehi-Had; Eugene C Gan; Claire E Walczak; Eva Nogales
XKCM1 acts on a single protofilament and requires the C terminus of tubulin.
Journal of molecular biology 2002;316(3):817-28.
2001: Claire E Walczak
Ran hits the ground running.
Nature cell biology 2001;3(3):E69-70.
2001: A Wilde; sofia lizarraga; L Zhang; Christiane Wiese; N R Gliksman; Claire E Walczak; Yixian Zheng
Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities.
Nature cell biology 2001;3(3):221-7.
2001: A Desai; Claire E Walczak
Assays for microtubule-destabilizing kinesins.
Methods in molecular biology (Clifton, N.J.) 2001;164():109-21.
2000: Susan L. Kline; Claire E Walczak
Microtubules in orbit.
The Journal of cell biology 2000;149(1):5-6.
2000: Claire E Walczak
Microtubule dynamics and tubulin interacting proteins.
Current opinion in cell biology 2000;12(1):52-6.
2000: Claire E Walczak
Molecular mechanisms of spindle function.
Genome biology 2000;1(1):REVIEWS101.
2000: R Tournebize; A Popov; Kazuhisa Kinoshita; Anthony J Ashford; Sonja Rybina; Andrei I Pozniakovsky; T U Mayer; Claire E Walczak; Eric Karsenti; Anthony A Hyman
Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts.
Nature cell biology 2000;2(1):13-9.
1999: Rebecca Heald; Claire E Walczak
Microtubule-based motor function in mitosis.
Current opinion in structural biology 1999;9(2):268-74.
1999: M Shirasu; A Yonetani; Claire E Walczak
Microtubule dynamics in Xenopus egg extracts.
Microscopy research and technique 1999;44(6):435-45.
1999: David J Sharp; Kelly L McDonald; HM Brown; Heinrich Matthies; Claire E Walczak; Ronald D Vale; Timothy J Mitchison; Jonathan M Scholey
The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles.
The Journal of cell biology 1999;144(1):125-38.
1999: Arshad Desai; S Verma; Timothy J Mitchison; Claire E Walczak
Kin I kinesins are microtubule-destabilizing enzymes.
Cell 1999;96(1):69-78.
1999: Arshad Desai; A Murray; Timothy J Mitchison; Claire E Walczak
The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro.
Methods in cell biology 1999;61():385-412.
1998: Claire E Walczak; Isabelle Vernos; Timothy J Mitchison; Eric Karsenti; Rebecca Heald
A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity.
Current biology : CB 1998;8(16):903-13.
1998: CM Field; K Oegema; Y Zheng; Timothy J Mitchison; Claire E Walczak
Purification of cytoskeletal proteins using peptide antibodies.
Methods in enzymology 1998;298():525-41.
1997: Arshad Desai; H W Deacon; Claire E Walczak; Timothy J Mitchison
A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12378-83.
1997: Claire E Walczak; S Verma; Timothy J Mitchison
XCTK2: a kinesin-related protein that promotes mitotic spindle assembly in Xenopus laevis egg extracts.
The Journal of cell biology 1997;136(4):859-70.
1996: Mark Hochstrasser; G L Carlson; Claire E Walczak; David L Nelson
Paramecium has two regulatory subunits of cyclic AMP-dependent protein kinase, one unique to cilia.
The Journal of eukaryotic microbiology 1996;43(4):356-62.
1996: Claire E Walczak; Timothy J Mitchison
Kinesin-related proteins at mitotic spindle poles: function and regulation.
Cell 1996;85(7):943-6.
1996: Claire E Walczak; Timothy J Mitchison; Arshad Desai
XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly.
Cell 1996;84(1):37-47.
1994: Claire E Walczak; David L Nelson
Regulation of dynein-driven motility in cilia and flagella.
Cell motility and the cytoskeleton 1994;27(2):101-7.
1993: Claire E Walczak; R A Anderson; David L Nelson
Identification of a family of casein kinases in Paramecium: biochemical characterization and cellular localization.
The Biochemical journal 1993;296 ( Pt 3)():729-35.
1993: Claire E Walczak; David L Nelson
In vitro phosphorylation of ciliary dyneins by protein kinases from Paramecium.
Journal of cell science 1993;106 ( Pt 4)():1369-76.
1993: Claire E Walczak; S P Marchese-Ragona; David L Nelson
Immunological comparison of 22S, 19S, and 12S dyneins from Paramecium cilia.
Cell motility and the cytoskeleton 1993;24(1):17-28.