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Scott Waldman

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Gilbert W Kim; Jieru Lin; Erik S Blomain; Scott A Waldman
New advances in models and strategies for developing anti-obesity drugs.
Scott A Waldman; Andre Terzic
Systems-based discovery advances drug development.
Gilbert W Kim; Jieru Lin; Scott A Waldman
GUCY2C: at the intersection of obesity and cancer.

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All Publications

2013: Gilbert W Kim; Jieru Lin; Erik S Blomain; Scott A Waldman
New advances in models and strategies for developing anti-obesity drugs.
Expert opinion on drug discovery 2013;8(6):655-71.
2013: Scott A Waldman; Andre Terzic
Systems-based discovery advances drug development.
Clinical pharmacology and therapeutics 2013;93(4):285-7.
2013: Gilbert W Kim; Jieru Lin; Scott A Waldman
GUCY2C: at the intersection of obesity and cancer.
Trends in endocrinology and metabolism: TEM 2013;24(4):165-73.
2013: Maria P Martinez Cantarin; Carlo B Ramirez; Scott A Waldman; Cataldo Doria; Adam M Frank; Scott W Keith; Warren R Maley; Bonita Falkner
The adipose tissue production of adiponectin is increased in end-stage renal disease.
Kidney international 2013;83(3):487-94.
2013: Adam Snook; Scott A Waldman
Advances in cancer immunotherapy.
Discovery medicine 2013;15(81):120-5.
2013: Terry Hyslop; Scott A Waldman
Guanylyl cyclase C as a biomarker in colorectal cancer.
Biomarkers in medicine 2013;7(1):159-67.
2013: Michael S Magee; Glen P Marszalowicz; Adam Snook; Scott A Waldman
Immunotherapeutic strategies to target prognostic and predictive markers of cancer.
Biomarkers in medicine 2013;7(1):23-35.
2013: Scott A Waldman; Andre Terzic
Translational medicine individualizes healthcare discovery, development and delivery. Foreword.
Biomarkers in medicine 2013;7(1):1-3.
2013: Francheska Colon-Gonzalez; Gilbert W Kim; Jieru Lin; Michael A Valentino; Scott A Waldman
Obesity pharmacotherapy: what is next?
Molecular aspects of medicine 2013;34(1):71-83.
2013: Terry Hyslop; Scott A Waldman
Molecular staging of node negative patients with colorectal cancer.
Journal of Cancer 2013;4(3):193-9.
2013: Scott A Waldman; Andre Terzic
Information hierarchies optimize patient-centered solutions.
Clinical pharmacology and therapeutics 2013;93(1):3-7.
2012: Scott A Waldman; Andre Terzic
Advancing pharmacometrics and systems pharmacology.
Clinical pharmacology and therapeutics 2012;92(5):535-7.
2012: Terry Hyslop; Stephanie Schulz; Alan Barkun; David S Weinberg; Scott A Waldman
Analytic lymph node number establishes staging accuracy by occult tumor burden in colorectal cancer.
Journal of surgical oncology 2012;106(1):24-30.
2012: Jian P Gong; Terry Hyslop; Stephanie Schulz; Scott A Waldman
GUCY2C molecular staging personalizes colorectal cancer patient management.
Biomarkers in medicine 2012;6(3):339-48.
2012: David S Zuzga; Scott A Waldman; Alessandro Bombonati; Peng Li; Joshua Pelta-Heller; Giovanni M Pitari
Phosphorylation of vasodilator-stimulated phosphoprotein Ser239 suppresses filopodia and invadopodia in colon cancer.
International journal of cancer. Journal international du cancer 2012;130(11):2539-48.
2012: Adam Snook; Michael S Magee; Glen P Marszalowicz; Stephanie Schulz; Scott A Waldman
Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C.
Cancer immunology, immunotherapy : CII 2012;61(5):713-23.
2012: Terry Hyslop; Stephanie Schulz; Alan Barkun; David S Weinberg; Scott A Waldman
Occult tumor burden contributes to racial disparities in stage-specific colorectal cancer outcomes.
Cancer 2012;118(9):2532-40.
2012: Alex Mejia; Stephanie Schulz; Terry Hyslop; David S Weinberg; Scott A Waldman
Molecular staging individualizing cancer management.
Journal of surgical oncology 2012;105(5):468-74.
2012: Scott A Waldman; Andre Terzic
The value proposition of molecular medicine.
Clinical and translational science 2012;5(1):108-10.
2011: Scott A Waldman; Andre Terzic
Patient-centric clinical pharmacology advances the path to personalized medicine.
Biomarkers in medicine 2011;5(6):697-700.
2011: Scott A Waldman; Andre Terzic
Widening the path to personalized medicine.
Clinical and translational science 2011;4(5):392-4.
2011: Scott A Waldman; Andre Terzic
Cardiovascular health: the global challenge.
Clinical pharmacology and therapeutics 2011;90(4):483-5.
2011: Michael A Valentino; Terry Hyslop; Gilbert W Kim; Peng Li; Jieru Lin; Michael S Magee; Glen Marszalowicz; Stephanie Schulz; Adam Snook; Scott A Waldman
A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.
The Journal of clinical investigation 2011;121(9):3578-88.
2011: Scott A Waldman; R J Hohl; G L Kearns; S J Swan; Andre Terzic
Clinical pharmacology as a foundation for translational science.
Clinical pharmacology and therapeutics 2011;90(1):10-3.
2011: Scott A Waldman; Andre Terzic
Clinical pharmacology at the core of translational science.
Expert review of clinical pharmacology 2011;4(3):303-5.
2011: Scott A Waldman; Andre Terzic
Bionic technologies transforming the science of healthcare delivery.
Clinical and translational science 2011;4(2):84-6.
2011: Barry B Goldberg; Daniel A Merton; Ji-Bin Liu; Flemming Forsberg; Kaijun Zhang; Madhukar Thakur; Stephanie Schulz; Robin Schanche; George F Murphy; Scott A Waldman
Contrast-enhanced ultrasound imaging of sentinel lymph nodes after peritumoral administration of Sonazoid in a melanoma tumor animal model.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2011;30(4):441-53.
2011: Scott A Waldman; Andre Terzic
Clinical translational science 2020: disruptive innovation redefines the discovery-application enterprise.
Clinical and translational science 2011;4(1):69-71.
2011: Richard C Crist; Jacquelyn J Roth; Scott A Waldman; Arthur M Buchberg
A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer.
PloS one 2011;6(8):e23665.
2010: Andre Terzic; Scott A Waldman
Translational medicine: path to personalized and public health.
Biomarkers in medicine 2010;4(6):787-90.
2010: Scott A Waldman; Andre Terzic
Clinical and translational science: from bench-bedside to global village.
Clinical and translational science 2010;3(5):254-7.
2010: Jieru Lin; Michael S Magee; Glen Marszalowicz; Adam Snook; Brian A Stoecker; Michael Valentino; Chang Chang; Peng Li; Scott A Waldman
Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.
Toxins 2010;2(8):2028-54.
2010: Scott A Waldman; Andre Terzic
Molecular therapy drives patient-centric health care paradigms.
Clinical and translational science 2010;3(4):170-1.
2010: Peng Li; Scott A Waldman
Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis.
Cancer biology & therapy 2010;10(3):211-8.
2010: Michael A Valentino; Andre Terzic; Scott A Waldman
Sizing up pharmacotherapy for obesity.
Clinical and translational science 2010;3(3):123-5.
2010: M A Valentino; Jieru Lin; Scott A Waldman
Central and peripheral molecular targets for antiobesity pharmacotherapy.
Clinical pharmacology and therapeutics 2010;87(6):652-62.
2010: Alex Mejia; Stephanie Schulz; Terry Hyslop; David S Weinberg; Scott A Waldman
Molecular staging estimates occult tumor burden in colorectal cancer.
Advances in clinical chemistry 2010;52():19-39.
2010: Inna Chervoneva; Yanyan Li; Stephanie Schulz; Sean Croker; Chantell Wilson; Scott A Waldman; Terry Hyslop
Selection of optimal reference genes for normalization in quantitative RT-PCR.
BMC bioinformatics 2010;11():253.
2010: Jieru Lin; Peng Li; Adam Snook; Stephanie Schulz; Abhijit Dasgupta; Terry Hyslop; Ahmara Vivian Gibbons; Glen Marszlowicz; Giovanni M Pitari; Scott A Waldman
The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Gastroenterology 2010;138(1):241-54.
2009: Scott A Waldman; Walter K Kraft; Timothy J Nelson; Andre Terzic
Clinical pharmacology: a paradigm for individualized medicine.
Biomarkers in medicine 2009;3(6):679-84.
2009: Scott A Waldman; Walter K Kraft; Timothy J Nelson; Andre Terzic
Experimental therapeutics: a paradigm for personalized medicine.
Clinical and translational science 2009;2(6):436-8.
2009: Peng Li; Jieru Lin; Stephanie Schulz; Giovanni M Pitari; Scott A Waldman
Can colorectal cancer be prevented or treated by oral hormone replacement therapy?
Current molecular pharmacology 2009;2(3):285-92.
2009: Alex Mejia; Stephanie Schulz; Terry Hyslop; David S Weinberg; Scott A Waldman
GUCY2C reverse transcriptase PCR to stage pN0 colorectal cancer patients.
Expert review of molecular diagnostics 2009;9(8):777-85.
2009: Li Gong; Philip Debruyne; Matthew Witek; Karl Nielsen; Adam Snook; Jieru Lin; Alessandro Bombonati; Juan P Palazzo; Stephanie Schulz; Scott A Waldman
Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis.
Clinical and translational science 2009;2(4):286-93.
2009: Vincenzo Ciocca; Alessandro Bombonati; Juan P Palazzo; Stephanie Schulz; Scott A Waldman
Guanylyl cyclase C is a specific marker for differentiating primary and metastatic ovarian mucinous neoplasms.
Histopathology 2009;55(2):182-8.
2009: Peng Li; Jieru Lin; G P Marszlowicz; M A Valentino; C Chang; Stephanie Schulz; G M Pitari; Scott A Waldman
GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?
Drug news & perspectives 2009;22(6):313-8.
2009: Scott A Waldman; Andre Terzic
Applications of microRNA in cancer: Exploring the advantages of miRNA.
Clinical and translational science 2009;2(3):248-9.
2009: Jieru Lin; Peng Li; Giovanni M Pitari; Stephanie Schulz; Scott A Waldman
Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target.
Future oncology (London, England) 2009;5(4):509-22.
2009: Adam Snook; Peng Li; Benjamin J Stafford; Elizabeth J Faul; Lan Huang; Ruth C Birbe; Alessandro Bombonati; Stephanie Schulz; Matthias J Schnell; Laurence C Eisenlohr; Scott A Waldman
Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease.
Cancer research 2009;69(8):3537-44.
2009: Wilhelm J Lubbe; David S Zuzga; Zengyi Zhou; Weili Fu; Joshua Pelta-Heller; Ruth J Muschel; Scott A Waldman; Giovanni M Pitari
Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9.
Cancer research 2009;69(8):3529-36.
2009: Scott A Waldman; Andre Terzic
Translational medicine in the era of health care reform.
Clinical and translational science 2009;2(2):96-7.
2009: Scott A Waldman; Andre Terzic
A study of microRNAs in silico and in vivo: diagnostic and therapeutic applications in cancer.
The FEBS journal 2009;276(8):2157-64.
2009: Scott A Waldman; Terry Hyslop; Stephanie Schulz; Alan Barkun; Karl Nielsen; Janis Haaf; Christine Bonaccorso; Yanyan Li; David S Weinberg
Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer.
JAMA : the journal of the American Medical Association 2009;301(7):745-52.
2009: Chang Chang; Glen Marszlowicz; Zac Waldman; Peng Li; Adam Snook; Jieru Lin; Stephanie Schulz; Scott A Waldman
Guanylyl cyclase C as a biomarker for targeted imaging and therapy of metastatic colorectal cancer.
Biomarkers in medicine 2009;3(1):33-45.
2009: Scott A Waldman; Andre Terzic
Molecular diagnostics. At the nexus of individualized medicine, health care delivery, and public policy.
Clinical and translational science 2009;2(1):6-8.
2008: Adam Snook; Lan Huang; Stephanie Schulz; Laurence C Eisenlohr; Scott A Waldman
Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens.
Clinical and translational science 2008;1(3):263-4.
2008: Peng Li; Stephanie Schulz; Giovanni M Pitari; Scott A Waldman
Sex modulates intestinal transformation by the tumor-suppressor GCC.
Clinical and translational science 2008;1(2):150.
2008: Peng Li; Stephanie Schulz; Giovanni M Pitari; Scott A Waldman
Sex modulates intestinal transformation by the tumor-suppressor GCC.
Clinical and translational science 2008;1(2):146-50.
2008: Scott A Waldman; Andre Terzic
The roadmap to personalized medicine.
Clinical and translational science 2008;1(2):93.
2008: Peng Li; Jieru Lin; Adam Snook; A V Gibbons; David S Zuzga; Stephanie Schulz; Giovanni M Pitari; Scott A Waldman
Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy.
Clinical and translational science 2008;1(2):163-7.
2008: Giovanni M Pitari; Jieru Lin; Fawad J Shah; Wilhelm J Lubbe; David S Zuzga; Peng Li; Stephanie Schulz; Scott A Waldman
Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells.
Carcinogenesis 2008;29(8):1601-7.
2008: Adam Snook; Benjamin J Stafford; Peng Li; Gene Tan; Lan Huang; Ruth Birbe; Stephanie Schulz; Matthias J Schnell; Mathew Thakur; Jay L Rothstein; Laurence C Eisenlohr; Scott A Waldman
Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity.
Journal of the National Cancer Institute 2008;100(13):950-61.
2008: Scott A Waldman; Andre Terzic
MicroRNA signatures as diagnostic and therapeutic targets.
Clinical chemistry 2008;54(6):943-4.
2008: Scott A Waldman; Andre Terzic
Clinical and translational sciences: at the intersection of molecular and individualized medicine.
Clinical and translational science 2008;1(1):6-8.
2008: Gabriela Plesa; Adam Snook; Scott A Waldman; Laurence C Eisenlohr
Derivation and fluidity of acutely induced dysfunctional CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5300-8.
2008: Scott A Waldman; Andre Terzic
Therapeutic burden in cancer revealed by molecular staging.
Biomarkers in medicine 2008;2(1):1-3.
2008: Xiaobing Tian; Allison M Michal; Peng Li; Henry Wolfe; Scott A Waldman; Eric Wickstrom
STa peptide analogs for probing guanylyl cyclase C.
Biopolymers 2008;90(5):713-23.
2007: Peng Li; Jieru Lin; Inna Chervoneva; Stephanie Schulz; Scott A Waldman; Giovanni M Pitari
Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.
The American journal of pathology 2007;171(6):1847-58.
2007: Adam Snook; Laurence C Eisenlohr; Jay L Rothstein; Scott A Waldman
Cancer mucosa antigens as a novel immunotherapeutic class of tumor-associated antigen.
Clinical pharmacology and therapeutics 2007;82(6):734-9.
2007: Giovanni M Pitari; Peng Li; Jieru Lin; David Zuzga; A V Gibbons; Adam Snook; Stephanie Schulz; Scott A Waldman
The paracrine hormone hypothesis of colorectal cancer.
Clinical pharmacology and therapeutics 2007;82(4):441-7.
2007: Peng Li; Stephanie Schulz; Alessandro Bombonati; Juan P Palazzo; Terry Hyslop; Yihuan Xu; Amy A Baran; Linda D Siracusa; Giovanni M Pitari; Scott A Waldman
Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.
Gastroenterology 2007;133(2):599-607.
2007: Adam Snook; Benjamin J Stafford; Laurence C Eisenlohr; Jay L Rothstein; Scott A Waldman
Mucosally restricted antigens as novel immunological targets for antitumor therapy.
Biomarkers in medicine 2007;1(1):187-202.
2007: Li Gong; Howard E Greenberg; James L Perhach; Scott A Waldman; walter kraft
The pharmacokinetics of taurolidine metabolites in healthy volunteers.
Journal of clinical pharmacology 2007;47(6):697-703.
2007: Márcio A F de Godoy; Chirag A Patel; Scott A Waldman; Motoya Katsuki; Raymond F Regan; Satish Rattan
H-ras inhibits RhoA/ROCK leading to a decrease in the basal tone in the internal anal sphincter.
Gastroenterology 2007;132(4):1401-9.
2007: Paolo Fortina; Larry J Kricka; David J Graves; Jason Young Park; Terry Hyslop; Felicia Tam; Naomi J Halas; Saul Surrey; Scott A Waldman
Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer.
Trends in biotechnology 2007;25(4):145-52.
2006: Scott A Waldman; Paolo Fortina; Saul Surrey; Terry Hyslop; Larry J Kricka; David J Graves
Opportunities for near-infrared thermal ablation of colorectal metastases by guanylyl cyclase C-targeted gold nanoshells.
Future oncology (London, England) 2006;2(6):705-16.
2006: Stephanie Schulz; Terry Hyslop; Janis Haaf; Christine Bonaccorso; Karl Nielsen; Matthew E Witek; Ruth Birbe; Juan P Palazzo; David Weinberg; Scott A Waldman
A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4545-52.
2006: Giovanni M Pitari; Tong Li; Ronnie I Baksh; Scott A Waldman
Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.
Molecular cancer therapeutics 2006;5(5):1190-6.
2006: Philip Debruyne; Matthew E Witek; Li Gong; Ruth Birbe; Inna Chervoneva; Tianru Jin; Claire Domon-Cell; Juan P Palazzo; Jean-Noel Freund; Peng Li; Giovanni M Pitari; Stephanie Schulz; Scott A Waldman
Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells.
Gastroenterology 2006;130(4):1191-206.
2006: Wilhelm J Lubbe; Zengyi Y Zhou; Weili Fu; David Zuzga; Stephanie Schulz; Rafael Fridman; Ruth J Muschel; Scott A Waldman; Giovanni M Pitari
Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1876-82.
2006: Anup K Majumdar; Laura Howard; Michael R Goldberg; Lisa Hickey; Marvin Constanzer; Paul L Rothenberg; Tami M Crumley; Deborah Panebianco; Thomas E Bradstreet; Arthur J Bergman; Scott A Waldman; Howard E Greenberg; Kathleen Butler; A Knops; Inge De Lepeleire; Nicole Michiels; Petty Kevin
Pharmacokinetics of aprepitant after single and multiple oral doses in healthy volunteers.
Journal of clinical pharmacology 2006;46(3):291-300.
2005: Matthew E Witek; Karl Nielsen; Rhonda Walters; Terry Hyslop; Juan P Palazzo; Stephanie Schulz; Scott A Waldman
The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(24 Pt 1):8549-56.
2005: Giovanni M Pitari; Ronnie I Baksh; David M Harris; Peng Li; Shiva Kazerounian; Scott A Waldman
Interruption of homologous desensitization in cyclic guanosine 3',5'-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins.
Cancer research 2005;65(23):11129-35.
2005: Glen S Frick; Giovanni M Pitari; David S Weinberg; Terry Hyslop; Stephanie Schulz; Scott A Waldman
Guanylyl cyclase C: a molecular marker for staging and postoperative surveillance of patients with colorectal cancer.
Expert review of molecular diagnostics 2005;5(5):701-13.
2005: Shiva Kazerounian; Giovanni M Pitari; Fawad J Shah; Glen S Frick; Muniswamy Madesh; Inez Ruiz-Stewart; Stephanie Schulz; Gyorgy Hajn\u2264czky; Scott A Waldman
Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins.
The Journal of pharmacology and experimental therapeutics 2005;314(3):1013-22.
2005: Ruth Birbe; Juan P Palazzo; Rhonda Walters; David Weinberg; Stephanie Schulz; Scott A Waldman
Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract.
Human pathology 2005;36(2):170-9.
2004: Julie A Stone; Elizabeth M Migoya; Lisa Hickey; Gregory A Winchell; Paul J Deutsch; Kalyan Ghosh; Amanda Freeman; Sheng Bi; Rajesh Desai; Stacy C Dilzer; Kenneth C Lasseter; walter kraft; Howard Greenberg; Scott A Waldman
Potential for interactions between caspofungin and nelfinavir or rifampin.
Antimicrobial agents and chemotherapy 2004;48(11):4306-14.
2004: Nancy G B Agrawal; Catherine Z Matthews; Ralph S Mazenko; Eric J Woolf; Arturo G Porras; Xun Chen; Jutta L Miller; Nicole Michiels; Martin Wehling; Armin Schultz; Alice B Gottlieb; walter kraft; Howard E Greenberg; Scott A Waldman; Sean P Curtis; Keith M Gottesdiener
The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.
Journal of clinical pharmacology 2004;44(10):1125-31.
2004: walter kraft; Jacqueline B McCrea; Gregory A Winchell; Alexandra D Carides; Richard Lowry; Eric J Woolf; Sandra E Kusma; Paul J Deutsch; Howard E Greenberg; Scott A Waldman
Indinavir and rifabutin drug interactions in healthy volunteers.
Journal of clinical pharmacology 2004;44(3):305-13.
2004: Inez Ruiz-Stewart; Satish R Tiyyagura; Jieru Lin; Shiva Kazerounian; Giovanni M Pitari; Stephanie Schulz; E Martin; Ferid Murad; Scott A Waldman
Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):37-42.
2004: Satish R Tiyyagura; Shiva Kazerounian; Stephanie Schulz; Scott A Waldman; Giovanni M Pitari
Reciprocal regulation and integration of signaling by intracellular calcium and cyclic GMP.
Vitamins and hormones 2004;69():69-94.
2004: walter kraft; Barry Steiger; Don Beussink; John N Quiring; Nancy Fitzgerald; Howard E Greenberg; Scott A Waldman
The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers.
Journal of clinical pharmacology 2004;44(1):67-72.
2004: Li Gong; Giovanni M Pitari; Stephanie Schulz; Scott A Waldman
Nitric oxide signaling: systems integration of oxygen balance in defense of cell integrity.
Current opinion in hematology 2004;11(1):7-14.
2003: Maria L Veronese; Lisa P Gillen; Ellen P Dorval; Walter W Hauck; Scott A Waldman; Howard E Greenberg
Effect of mibefradil on CYP3A4 in vivo.
Journal of clinical pharmacology 2003;43(10):1091-100.
2003: Joanne Burke; walter kraft; Howard E Greenberg; Melanie Gleave; Giovanni M Pitari; Sandi VanBuren; John A Wagner; Scott A Waldman
Relationship of arachidonic acid concentration to cyclooxygenase-dependent human platelet aggregation.
Journal of clinical pharmacology 2003;43(9):983-9.
2003: Maria L Veronese; Lisa P Gillen; Joanne P Burke; Ellen P Dorval; Walter W Hauck; Ed Pequignot; Scott A Waldman; Howard E Greenberg
Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice.
Journal of clinical pharmacology 2003;43(8):831-9.
2003: Philip Debruyne; Scott A Waldman; Stephanie Schulz
Pathological staging and therapy of oesophageal and gastric cancer.
Expert opinion on pharmacotherapy 2003;4(7):1083-96.
2003: Robert A Blum; Anup Majumdar; Jacqueline B McCrea; John Busillo; Laura H Orlowski; Deborah Panebianco; Michael Hesney; Petty Kevin; Michael R Goldberg; M Gail Murphy; Keith M Gottesdiener; Carolyn M Hustad; Christian Lates; walter kraft; Sandi Van Buren; Scott A Waldman; Howard E Greenberg
Effects of aprepitant on the pharmacokinetics of ondansetron and granisetron in healthy subjects.
Clinical therapeutics 2003;25(5):1407-19.
2003: Sandeep Rathi; Shiva Kazerounian; Kuldip Banwait; Stephanie Schulz; Scott A Waldman; Satish Rattan
Functional and molecular characterization of beta-adrenoceptors in the internal anal sphincter.
The Journal of pharmacology and experimental therapeutics 2003;305(2):615-24.
2003: Giovanni M Pitari; Leonid V Zingman; Denice M Hodgson; Alexey E Alekseev; Shiva Kazerounian; Martin Bienengraeber; Gyorgy Hajn\u2264czky; Andre Terzic; Scott A Waldman
Bacterial enterotoxins are associated with resistance to colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2695-9.
2002: Jason Young Park; Stephanie Schulz; Janis Haaf; John C. Kairys; Scott A Waldman
Ectopic expression of guanylyl cyclase C in adenocarcinomas of the esophagus and stomach.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(8):739-44.
2002: Scott A Waldman
Does potency predict clinical efficacy? Illustration through an antihistamine model.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2002;89(1):7-11; quiz 11-2, 77.
2002: Inez Ruiz-Stewart; Shiva Kazerounian; Giovanni M Pitari; Stephanie Schulz; Scott A Waldman
Soluble guanylate cyclase is allosterically inhibited by direct interaction with 2-substituted adenine nucleotides.
European journal of biochemistry / FEBS 2002;269(8):2186-93.
2002: Shiva Kazerounian; Giovanni M Pitari; Inez Ruiz-Stewart; Stephanie Schulz; Scott A Waldman
Nitric oxide activation of soluble guanylyl cyclase reveals high and low affinity sites that mediate allosteric inhibition by calcium.
Biochemistry 2002;41(10):3396-404.
2002: Julie A Stone; Sherry D Holland; Peter J Wickersham; Andrew Sterrett; Michael Schwartz; Cynthia Bonfiglio; Michael Hesney; Gregory A Winchell; Paul J Deutsch; Howard Greenberg; Thomas L Hunt; Scott A Waldman
Single- and multiple-dose pharmacokinetics of caspofungin in healthy men.
Antimicrobial agents and chemotherapy 2002;46(3):739-45.
2001: M D Di Guglielmo; Jason Young Park; Stephanie Schulz; Scott A Waldman
Nucleotide requirements for CDX2 binding to the cis promoter element mediating intestine-specific expression of guanylyl cyclase C.
FEBS letters 2001;507(2):128-32.
2001: T A Fava; R Desnoyers; Stephanie Schulz; Jason Young Park; David Weinberg; E Mitchell; Scott A Waldman
Ectopic expression of guanylyl cyclase C in CD34+ progenitor cells in peripheral blood.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(19):3951-9.
2001: Giovanni M Pitari; M D Di Guglielmo; Jason Young Park; Stephanie Schulz; Scott A Waldman
Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7846-51.
2001: walter kraft; Scott A Waldman
Manufacturer's drug interaction and postmarketing adverse event data: what are appropriate uses?
Drug safety : an international journal of medical toxicology and drug experience 2001;24(9):637-43.
2000: Howard E Greenberg; Keith M Gottesdiener; M Huntington; P Wong; Patrick Larson; L Wildonger; Lisa P Gillen; Ellen P Dorval; Scott A Waldman
A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers.
Journal of clinical pharmacology 2000;40(12 Pt 2):1509-15.
2000: Thomayant Prueksaritanont; Jose M Vega; John D Rogers; KD Gagliano; Howard E Greenberg; Lisa P Gillen; MJ Brucker; Debra McLoughlin; P H Wong; Scott A Waldman
Simvastatin does not affect CYP3A activity, quantified by the erythromycin breath test and oral midazolam pharmacokinetics, in healthy male subjects.
Journal of clinical pharmacology 2000;40(11):1274-9.
2000: K A Lucas; Giovanni M Pitari; Shiva Kazerounian; Inez Ruiz-Stewart; Jason Young Park; Stephanie Schulz; K P Chepenik; Scott A Waldman
Guanylyl cyclases and signaling by cyclic GMP.
Pharmacological reviews 2000;52(3):375-414.
2000: David S Weinberg; R Desnoyers; AS Gelmann; Bruce M Boman; Scott A Waldman
Postoperative management of local colorectal cancer: therapy and surveillance.
Seminars in gastrointestinal disease 2000;11(3):152-6.
2000: Jason Young Park; Stephanie Schulz; Scott A Waldman
Intestine-specific activity of the human guanylyl cyclase C promoter is regulated by Cdx2.
Gastroenterology 2000;119(1):89-96.
2000: PN Zannikos; Bradford K Jensen; Bruno X Boutouyrie; L Tripp; L Yongyi; T McGowan; Scott A Waldman; Howard E Greenberg
Pharmacokinetics and safety of single intravenous infusions of the adenosine agonist, AMP 579, in patients with end-stage renal insufficiency.
Journal of clinical pharmacology 2000;40(7):745-51.
2000: AS Gelmann; R Desnoyers; Burt Cagir; David Weinberg; Bruce M Boman; Scott A Waldman
Colorectal cancer staging and adjuvant chemotherapy.
Expert opinion on pharmacotherapy 2000;1(4):737-55.
2000: J M Pearlman; S P Prawer; M T Barber; SJ Parkinson; Stephanie Schulz; Jason Young Park; M Zook; Scott A Waldman
A splice variant of the transcript for guanylyl cyclase C is expressed in human colon and colorectal cancer cells.
Digestive diseases and sciences 2000;45(2):298-305.
1999: Burt Cagir; AS Gelmann; Jason Young Park; T Fava; A Tankelevitch; E W Bittner; Eric J Weaver; Juan P Palazzo; David Weinberg; Robert D Fry; Scott A Waldman
Guanylyl cyclase C messenger RNA is a biomarker for recurrent stage II colorectal cancer.
Annals of internal medicine 1999;131(11):805-12.
1999: Scott A Waldman; Andre Terzic
The Molecular Therapeutics Section of the American Society for Clinical Pharmacology and Therapeutics.
Clinical pharmacology and therapeutics 1999;66(4):336-7.
1999: SJ Parkinson; A Jovanovic; S Jovanovic; F Wagner; Andre Terzic; Scott A Waldman
Regulation of nitric oxide-responsive recombinant soluble guanylyl cyclase by calcium.
Biochemistry 1999;38(20):6441-8.
1999: W Zhang; I Mannan; Stephanie Schulz; SJ Parkinson; Alexey E Alekseev; Luis Alberto Gomez; Andre Terzic; Scott A Waldman
Interruption of transmembrane signaling as a novel antisecretory strategy to treat enterotoxigenic diarrhea.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):913-22.
1999: Stephanie Schulz; Scott A Waldman
The guanylyl cyclase family of natriuretic peptide receptors.
Vitamins and hormones 1999;57():123-51.
1998: Manimekalai M Thiyagarajan; Scott A Waldman; M Noè; Eric B Kmiec
Binding characteristics of Ustilago maydis topoisomerase I to DNA containing secondary structures.
European journal of biochemistry / FEBS 1998;255(2):347-55.
1998: MN Gharaibeh; Lisa P Gillen; B Osborne; J I Schwartz; Scott A Waldman
Effect of multiple doses of rifampin on the [14C N-methyl] erythromycin breath test in healthy male volunteers.
Journal of clinical pharmacology 1998;38(6):492-5.
1998: Scott A Waldman; M Barber; J Pearlman; Jason Young Park; R George; SJ Parkinson
Heterogeneity of guanylyl cyclase C expressed by human colorectal cancer cell lines in vitro.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(6):505-14.
1998: walter kraft; Howard E Greenberg; Scott A Waldman
Paradoxical hypotension and bradycardia after intravenous arginine vasopressin.
Journal of clinical pharmacology 1998;38(3):283-6.
1998: Scott A Waldman; Burt Cagir; Jan Rakinic; Robert D Fry; Scott D Goldstein; G Isenberg; M Barber; S Biswas; Corrado Minimo; Juan P Palazzo; Pauline K Park; David Weinberg
Use of guanylyl cyclase C for detecting micrometastases in lymph nodes of patients with colon cancer.
Diseases of the colon and rectum 1998;41(3):310-5.
1997: S P Deshmane; SJ Parkinson; S S Crupper; D C Robertson; Stephanie Schulz; Scott A Waldman
Cytoplasmic domains mediate the ligand-induced affinity shift of guanylyl cyclase C.
Biochemistry 1997;36(42):12921-9.
1997: David S Weinberg; B Ruggeri; M T Barber; S Biswas; S Miknyocki; Scott A Waldman
Cholecystokinin A and B receptors are differentially expressed in normal pancreas and pancreatic adenocarcinoma.
The Journal of clinical investigation 1997;100(3):597-603.
1997: SJ Parkinson; Alexey E Alekseev; Luis Alberto Gomez; F Wagner; Andre Terzic; Scott A Waldman
Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine.
The Journal of biological chemistry 1997;272(2):754-8.
1996: S L Carrithers; M T Barber; S Biswas; SJ Parkinson; Pauline K Park; S D Goldstein; Scott A Waldman
Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14827-32.
1996: Scott A Waldman; C Vitow; B Osborne; Lisa P Gillen; D C Argentieri; Frankie A Wong; I L Smith; Andrew T Chow; J Misiti; TD Bjornsson
Pharmacokinetics and pharmacodynamics of tepoxalin after single oral dose administration to healthy volunteers.
Journal of clinical pharmacology 1996;36(5):462-8.
1996: S V Ryan; S L Carrithers; SJ Parkinson; C Skurk; C Nuss; PM Pooler; Charles S Owen; Allan M Lefer; Scott A Waldman
Hypotensive mechanisms of amifostine.
Journal of clinical pharmacology 1996;36(4):365-73.
1996: S L Carrithers; SJ Parkinson; S D Goldstein; Pauline K Park; R W Urbanski; Scott A Waldman
Escherichia coli heat-stable enterotoxin receptors. A novel marker for colorectal tumors.
Diseases of the colon and rectum 1996;39(2):171-81.
1995: T Murohara; SJ Parkinson; Scott A Waldman; Allan M Lefer
Inhibition of nitric oxide biosynthesis promotes P-selectin expression in platelets. Role of protein kinase C.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(11):2068-75.
1995: A N Kong; L Tomasko; Scott A Waldman; B Osborne; Paul J Deutsch; Michael R Goldberg; TD Bjornsson
Losartan does not affect the pharmacokinetics and pharmacodynamics of warfarin.
Journal of clinical pharmacology 1995;35(10):1008-15.
1995: R Urbanski; S L Carrithers; Scott A Waldman
Internalization of E. coli ST mediated by guanylyl cyclase C in T84 human colon carcinoma cells.
Biochimica et biophysica acta 1995;1245(1):29-36.
1995: S P Deshmane; S L Carrithers; SJ Parkinson; S S Crupper; D C Robertson; Scott A Waldman
Rat guanylyl cyclase C expressed in COS-7 cells exhibits multiple affinities for Escherichia coli heat-stable enterotoxin.
Biochemistry 1995;34(28):9095-102.
1995: A C Patrinellis; Scott A Waldman
Allosteric regulation by calcium of rabbit polyclonal anti-cyclic GMP antibody.
Biochimica et biophysica acta 1995;1243(2):143-50.
1995: Scott A Waldman; J Morganroth
Effects of food on the bioequivalence of different verapamil sustained-release formulations.
Journal of clinical pharmacology 1995;35(2):163-9.
1995: Michael R Goldberg; T E Bradstreet; E J McWilliams; Wesley Tanaka; S Lipert; TD Bjornsson; Scott A Waldman; B Osborne; L Pivadori; G Lewis
Biochemical effects of losartan, a nonpeptide angiotensin II receptor antagonist, on the renin-angiotensin-aldosterone system in hypertensive patients.
Hypertension 1995;25(1):37-46.
1994: Scott A Waldman; K Phillips; SJ Parkinson
Intestinal kinetics and dynamics of Escherichia coli heat-stabile enterotoxin in suckling mice.
The Journal of infectious diseases 1994;170(6):1498-507.
1994: S L Carrithers; SJ Parkinson; S Goldstein; Pauline K Park; D C Robertson; Scott A Waldman
Escherichia coli heat-stable toxin receptors in human colonic tumors.
Gastroenterology 1994;107(6):1653-61.
1994: SJ Parkinson; S L Carrithers; Scott A Waldman
Opposing adenine nucleotide-dependent pathways regulate guanylyl cyclase C in rat intestine.
The Journal of biological chemistry 1994;269(36):22683-90.
1994: Dale C Leitman; Scott A Waldman; Ferid Murad
Regulation of particulate guanylate cyclase by natriuretic peptides and Escherichia coli heat-stable enterotoxin.
Advances in pharmacology (San Diego, Calif.) 1994;26():67-86.
1993: S Hakki; D C Robertson; Scott A Waldman
A 56 kDa binding protein for Escherichia coli heat-stable enterotoxin isolated from the cytoskeleton of rat intestinal membrane does not possess guanylate cyclase activity.
Biochimica et biophysica acta 1993;1152(1):1-8.
1993: S Hakki; M Crane; M Hugues; P O'Hanley; Scott A Waldman
Solubilization and characterization of functionally coupled Escherichia coli heat-stable toxin receptors and particulate guanylate cyclase associated with the cytoskeleton compartment of intestinal membranes.
The International journal of biochemistry 1993;25(4):557-66.
1992: M R Crane; M Hugues; P D O'Hanley; Scott A Waldman
Identification of two affinity states of low affinity receptors for Escherichia coli heat-stable enterotoxin: correlation of occupation of lower affinity state with guanylate cyclase activation.
Molecular pharmacology 1992;41(6):1073-80.
1992: M Hugues; M R Crane; B R Thomas; D Robertson; H Gazzano; P O'Hanley; Scott A Waldman
Affinity purification of functional receptors for Escherichia coli heat-stable enterotoxin from rat intestine.
Biochemistry 1992;31(1):12-6.
1991: M Hugues; M Crane; S Hakki; P O'Hanley; Scott A Waldman
Identification and characterization of a new family of high-affinity receptors for Escherichia coli heat-stable enterotoxin in rat intestinal membranes.
Biochemistry 1991;30(44):10738-45.
1991: H Gazzano; H I Wu; Scott A Waldman
Activation of particulate guanylate cyclase by Escherichia coli heat-stable enterotoxin is regulated by adenine nucleotides.
Infection and immunity 1991;59(4):1552-7.
1991: H Gazzano; H I Wu; Scott A Waldman
Adenine nucleotide regulation of particulate guanylate cyclase from rat lung.
Biochimica et biophysica acta 1991;1077(1):99-106.
1991: Dale C Leitman; Scott A Waldman; Ferid Murad
Identification of atrial natriuretic peptide receptors in cultured cells.
Methods in enzymology 1991;195():436-46.
1991: Scott A Waldman; Dale C Leitman; Ferid Murad
Copurification of atrial natriuretic peptide receptor and particulate guanylyl cyclase.
Methods in enzymology 1991;195():397-404.
1991: Scott A Waldman; Dale C Leitman; Ferid Murad
Immunoaffinity purification of soluble guanylyl cyclase.
Methods in enzymology 1991;195():391-6.
1990: M R Crane; P O'Hanley; Scott A Waldman
Rat intestinal cell atrial natriuretic peptide receptor coupled to guanylate cyclase.
Gastroenterology 1990;99(1):125-31.
1990: K Ivens; H Gazzano; P O'Hanley; Scott A Waldman
Heterogeneity of intestinal receptors for Escherichia coli heat-stable enterotoxin.
Infection and immunity 1990;58(6):1817-20.
1989: Scott A Waldman; R M Rapoport; R R Fiscus; Dale C Leitman; L Y Chang; Ferid Murad
Regulation of particulate guanylate cyclase by atriopeptins: relation between peptide structure, receptor binding, and enzyme kinetics.
Biochimica et biophysica acta 1989;999(2):157-62.
1989: Scott A Waldman; Dale C Leitman; L Y Chang; Ferid Murad
Comparison of particulate guanylate cyclase in cells with and without atrial natriuretic peptide receptor binding activity.
Molecular and cellular biochemistry 1989;90(1):19-25.
1989: Scott A Waldman; P O'Hanley
Influence of a glycine or proline substitution on the functional properties of a 14-amino-acid analog of Escherichia coli heat-stable enterotoxin.
Infection and immunity 1989;57(8):2420-4.
1989: S Carr; H Gazzano; Scott A Waldman
Regulation of particulate guanylate cyclase by Escherichia coli heat-stable enterotoxin: receptor binding and enzyme kinetics.
The International journal of biochemistry 1989;21(11):1211-5.
1988: Brian M Bennett; H Schröder; L D Hayward; Scott A Waldman; Ferid Murad
Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation, and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate.
Circulation research 1988;63(4):693-701.
1988: Scott A Waldman; Dale C Leitman; J Andresen; Ferid Murad
Guanylate cyclase and the adrenal natriuretic factor receptor.
Science (New York, N.Y.) 1988;240(4853):805-6.
1988: H Schröder; Dale C Leitman; Brian M Bennett; Scott A Waldman; Ferid Murad
Glyceryl trinitrate-induced desensitization of guanylate cyclase in cultured rat lung fibroblasts.
The Journal of pharmacology and experimental therapeutics 1988;245(2):413-8.
1988: Dale C Leitman; V L Agnost; R M Catalano; H Schröder; Scott A Waldman; Brian M Bennett; J J Tuan; Ferid Murad
Atrial natriuretic peptide, oxytocin, and vasopressin increase guanosine 3',5'-monophosphate in LLC-PK1 kidney epithelial cells.
Endocrinology 1988;122(4):1478-85.
1988: Dale C Leitman; J W Andresen; R M Catalano; Scott A Waldman; J J Tuan; Ferid Murad
Atrial natriuretic peptide binding, cross-linking, and stimulation of cyclic GMP accumulation and particulate guanylate cyclase activity in cultured cells.
The Journal of biological chemistry 1988;263(8):3720-8.
1988: Scott A Waldman; Ferid Murad
Biochemical mechanisms underlying vascular smooth muscle relaxation: the guanylate cyclase-cyclic GMP system.
Journal of cardiovascular pharmacology 1988;12 Suppl 5():S115-8.
1987: Ferid Murad; Dale C Leitman; Brian M Bennett; C Molina; Scott A Waldman
Regulation of guanylate cyclase by atrial natriuretic factor and the role of cyclic GMP in vasodilation.
The American journal of the medical sciences 1987;294(3):139-43.
1986: Y Kamisaki; S Saheki; M Nakane; J A Palmieri; T Kuno; B Y Chang; Scott A Waldman; Ferid Murad
Soluble guanylate cyclase from rat lung exists as a heterodimer.
The Journal of biological chemistry 1986;261(16):7236-41.
1986: T Kuno; J W Andresen; Y Kamisaki; Scott A Waldman; L Y Chang; S Saheki; Dale C Leitman; M Nakane; Ferid Murad
Co-purification of an atrial natriuretic factor receptor and particulate guanylate cyclase from rat lung.
The Journal of biological chemistry 1986;261(13):5817-23.
1986: T Kuno; Y Kamisaki; Scott A Waldman; J Gariepy; G Schoolnik; Ferid Murad
Characterization of the receptor for heat-stable enterotoxin from Escherichia coli in rat intestine.
The Journal of biological chemistry 1986;261(3):1470-6.
1986: Scott A Waldman; T Kuno; Y Kamisaki; L Y Chang; J Gariepy; P O'Hanley; G Schoolnik; Ferid Murad
Intestinal receptor for heat-stable enterotoxin of Escherichia coli is tightly coupled to a novel form of particulate guanylate cyclase.
Infection and immunity 1986;51(1):320-6.
1985: Dale C Leitman; Scott A Waldman; R M Rapoport; Ferid Murad
Specific atrial natriuretic factor receptors mediate increased cyclic GMP accumulation in cultured bovine aortic endothelial and smooth muscle cells.
Transactions of the Association of American Physicians 1985;98():243-52.
1984: Scott A Waldman; P O'Hanley; S Falkow; G Schoolnik; Ferid Murad
A simple, sensitive, and specific assay for the heat-stable enterotoxin of Escherichia coli.
The Journal of infectious diseases 1984;149(1):83-9.