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Herman Waldmann

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Howie Duncan; Nolan Kathleen F; Daley Stephen; Butterfield Emma; Adams Elizabeth; Garcia-Rueda Hugo; Thompson Claire; Saunders Nigel J; Cobbold Stephen P; Tone Yukiko; Tone Masahide; Waldmann Herman
MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation.
Cobbold Stephen P; Adams Elizabeth; Farquhar Claire A; Nolan Kathleen F; Howie Duncan; Lui Kathy O; Fairchild Paul J; Mellor Andrew L; Ron David; Waldmann Herman
Infectious tolerance via the consumption of essential amino acids and mTOR signaling.
Waldmann Herman; Cobbold Stephen
Regulatory T cells: context matters.

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All Publications

2009: Howie Duncan; Nolan Kathleen F; Daley Stephen; Butterfield Emma; Adams Elizabeth; Garcia-Rueda Hugo; Thompson Claire; Saunders Nigel J; Cobbold Stephen P; Tone Yukiko; Tone Masahide; Waldmann Herman
MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4197-204.
2009: Cobbold Stephen P; Adams Elizabeth; Farquhar Claire A; Nolan Kathleen F; Howie Duncan; Lui Kathy O; Fairchild Paul J; Mellor Andrew L; Ron David; Waldmann Herman
Infectious tolerance via the consumption of essential amino acids and mTOR signaling.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):12055-60.
2009: Waldmann Herman; Cobbold Stephen
Regulatory T cells: context matters.
Immunity 2009;30(5):613-5.
2009: Clatworthy Menna R; Friend Peter J; Calne Roy Y; Rebello Perpetua R U; Hale Geoffrey; Waldmann Herman; Watson Christopher J E
Alemtuzumab (CAMPATH-1H) for the treatment of acute rejection in kidney transplant recipients: long-term follow-up.
Transplantation 2009;87(7):1092-5.
2009: Lui Kathy O; Waldmann Herman; Fairchild Paul J
Embryonic stem cells: overcoming the immunological barriers to cell replacement therapy.
Current stem cell research & therapy 2009;4(1):70-80.
2008: Li Z; Benghiat F S; Charbonnier L Marie; Kubjak C; Rivas M N; Cobbold S P; Waldmann H; De Wilde V; Petein M; Schuind F; Goldman M; Le Moine A
CD8+ T-Cell depletion and rapamycin synergize with combined coreceptor/stimulation blockade to induce robust limb allograft tolerance in mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(12):2527-36.
2008: Daley S R; Cobbold S P; Waldmann H
Fc-disabled anti-mouse CD40L antibodies retain efficacy in promoting transplantation tolerance.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(11):2265-71.
2008: Waldmann Herman; Adams Elizabeth; Fairchild Paul; Cobbold Stephen
Regulation and privilege in transplantation tolerance.
Journal of clinical immunology 2008;28(6):716-25.
2008: Waldmann Herman
Tolerance can be infectious.
Nature immunology 2008;9(9):1001-3.
2008: Waldmann Herman; Adams Elizabeth; Cobbold Stephen
Reprogramming the immune system: co-receptor blockade as a paradigm for harnessing tolerance mechanisms.
Immunological reviews 2008;223():361-70.
2008: Zhou Zhaocai; Tone Yukiko; Song Xiaomin; Furuuchi Keiji; Lear James D; Waldmann Herman; Tone Masahide; Greene Mark I; Murali Ramachandran
Structural basis for ligand-mediated mouse GITR activation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(2):641-5.
2008: Waldmann Herman
Special regulatory T cell review: The suppression problem!
Immunology 2008;123(1):11-2.
2007: Robertson Nathan J; Brook Frances A; Gardner Richard L; Cobbold Stephen P; Waldmann Herman; Fairchild Paul J
Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(52):20920-5.
2007: Fairchild Paul J; Robertson Nathan J; Minger Stephen L; Waldmann Herman
Embryonic stem cells: protecting pluripotency from alloreactivity.
Current opinion in immunology 2007;19(5):596-602.
2007: Daley Stephen R; Ma Jianbo; Adams Elizabeth; Cobbold Stephen P; Waldmann Herman
A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):3648-54.
2007: Yates Stephen F; Paterson Alison M; Nolan Kathleen F; Cobbold Stephen P; Saunders Nigel J; Waldmann Herman; Fairchild Paul J
Induction of regulatory T cells and dominant tolerance by dendritic cells incapable of full activation.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):967-76.
2007: Robertson Nathan J; Fairchild Paul J; Waldmann Herman
Ectopic transplantation of tissues under the kidney capsule.
Methods in molecular biology (Clifton, N.J.) 2007;380():347-53.
2007: Nolan Kathleen F; Cobbold Stephen P; Waldmann Herman
SAGE analysis of cell types involved in tolerance induction.
Methods in molecular biology (Clifton, N.J.) 2007;380():225-51.
2007: Fairchild Paul J; Nolan Kathleen F; Waldmann Herman
Genetic modification of dendritic cells through the directed differentiation of embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2007;380():59-72.
2006: Cobbold Stephen P; Adams Elizabeth; Graca Luis; Daley Stephen; Yates Stephen; Paterson Alison; Robertson Nathan J; Nolan Kathleen F; Fairchild Paul J; Waldmann Herman
Immune privilege induced by regulatory T cells in transplantation tolerance.
Immunological reviews 2006;213():239-55.
2006: Waldmann Herman; Adams Elizabeth; Fairchild Paul; Cobbold Stephen
Infectious tolerance and the long-term acceptance of transplanted tissue.
Immunological reviews 2006;212():301-13.
2006: Glatting Gerhard; Müller Marguerite; Koop Bernd; Hohl Kathrin; Friesen Claudia; Neumaier Bernd; Berrie Eleanor; Bird Pru; Hale Geoffrey; Blumstein Norbert M; Waldmann Herman; Bunjes Donald; Reske Sven N
Anti-CD45 monoclonal antibody YAML568: A promising radioimmunoconjugate for targeted therapy of acute leukemia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(8):1335-41.
2006: Waldmann Herman; Chen Tse-Ching; Graca Luis; Adams Elizabeth; Daley Stephen; Cobbold Stephen; Fairchild Paul J
Regulatory T cells in transplantation.
Seminars in immunology 2006;18(2):111-9.
2006: Coles Alasdair J; Cox Amanda; Le Page Emmanuelle; Jones Joanne; Trip S Anand; Deans Jackie; Seaman Shaun; Miller David H; Hale Geoff; Waldmann Herman; Compston D Alastair
The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy.
Journal of neurology 2006;253(1):98-108.
2006: Graca Luis; Waldmann Herman
Reprogramming the immune system using antibodies.
Methods in molecular biology (Clifton, N.J.) 2006;333():247-68.
2006: Graca Luis; Daley Stephen; Fairchild Paul J; Cobbold Stephen P; Waldmann Herman
Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning.
BMC immunology 2006;7():9.
2005: Paterson A M; Yates S F; Nolan K F; Waldmann H
The new immunosuppression: intervention at the dendritic cell-T-cell interface.
Current drug targets. Immune, endocrine and metabolic disorders 2005;5(4):397-411.
2005: Cox Amanda L; Thompson Sara A J; Jones Joanne L; Robertson Vicki H; Hale Geoff; Waldmann Herman; Compston D Alastair S; Coles Alasdair J
Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis.
European journal of immunology 2005;35(11):3332-42.
2005: Novitzky N; Thomas V; Hale G; Waldmann H
Myeloablative conditioning is well tolerated by older patients receiving T-cell-depleted grafts.
Bone marrow transplantation 2005;36(8):675-82.
2005: Waldmann Herman; Hale Geoff
CAMPATH: from concept to clinic.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2005;360(1461):1707-11.
2005: Keymeulen Bart; Vandemeulebroucke Evy; Ziegler Anette G; Mathieu Chantal; Kaufman Leonard; Hale Geoff; Gorus Frans; Goldman Michel; Walter Markus; Candon Sophie; Schandene Liliane; Crenier Laurent; De Block Christophe; Seigneurin Jean-Marie; De Pauw Pieter; Pierard Denis; Weets Ilse; Rebello Peppy; Bird Pru; Berrie Eleanor; Frewin Mark; Waldmann Herman; Bach Jean-François; Pipeleers Daniel; Chatenoud Lucienne
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes.
The New England journal of medicine 2005;352(25):2598-608.
2005: Watson Christopher J E; Bradley J Andrew; Friend Peter J; Firth John; Taylor Craig J; Bradley John R; Smith Kenneth G C; Thiru Sathia; Jamieson Neville V; Hale Geoff; Waldmann Herman; Calne Roy
Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(6):1347-53.
2005: Benghiat Fleur Samantha; Graca Luis; Braun Michel Y; Detienne Sophie; Moore Fabrice; Buonocore Sofia; Flamand Véronique; Waldmann Herman; Goldman Michel; Le Moine Alain
Critical influence of natural regulatory CD25+ T cells on the fate of allografts in the absence of immunosuppression.
Transplantation 2005;79(6):648-54.
2005: Graca Luis; Chen Tse-Ching; Le Moine Alain; Cobbold Stephen P; Howie Duncan; Waldmann Herman
Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells.
Trends in immunology 2005;26(3):130-5.
2005: Fairchild Paul J; Nolan Kathleen F; Cartland Siân; Waldmann Herman
Embryonic stem cells: a novel source of dendritic cells for clinical applications.
International immunopharmacology 2005;5(1):13-21.
2005: Fairchild Paul J; Robertson Nathan J; Cartland Siân; Nolan Kathleen F; Waldmann Herman
Cell replacement therapy and the evasion of destructive immunity.
Stem cell reviews 2005;1(2):159-67.
2005: Waldmann H; Graca L; Adams E; Fairchild P; Cobbold S
Regulatory T cells in transplantation tolerance.
Current topics in microbiology and immunology 2005;293():249-64.
2004: Winsor-Hines Dawn; Merrill Christopher; O'Mahony Mark; Rao Patricia E; Cobbold Stephen P; Waldmann Herman; Ringler Douglas J; Ponath Paul D
Induction of immunological tolerance/hyporesponsiveness in baboons with a nondepleting CD4 antibody.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4715-23.
2004: Fairchild Paul J; Cartland Siân; Nolan Kathleen F; Waldmann Herman
Embryonic stem cells and the challenge of transplantation tolerance.
Trends in immunology 2004;25(9):465-70.
2004: Hale Geoff; Rebello Peppy; Brettman Lee R; Fegan Chris; Kennedy Ben; Kimby Eva; Leach Mike; Lundin Jeanette; Mellstedt Håkan; Moreton Paul; Rawstron Andy C; Waldmann Herman; Osterborg Anders; Hillmen Peter
Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration.
Blood 2004;104(4):948-55.
2004: Waldmann Herman; Cobbold Stephen
Exploiting tolerance processes in transplantation.
Science (New York, N.Y.) 2004;305(5681):209-12.
2004: Graca Luis; Le Moine Alain; Lin Chun-Yen; Fairchild Paul J; Cobbold Stephen P; Waldmann Herman
Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10122-6.
2004: Chen Tse-Ching; Waldmann Herman; Fairchild Paul J
Induction of dominant transplantation tolerance by an altered peptide ligand of the male antigen Dby.
The Journal of clinical investigation 2004;113(12):1754-62.
2004: Murphy Conor C; Greiner Kathrin; Plskova Jarka; Duncan Linda; Frost Andrew; Isaacs John D; Rebello Peppy; Waldmann Herman; Hale Geoff; Forrester John V; Dick Andrew D
Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis.
Archives of ophthalmology 2004;122(6):845-51.
2004: Cobbold Stephen P; Castejon Raquel; Adams Elizabeth; Zelenika Diana; Graca Luis; Humm Susan; Waldmann Herman
Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6003-10.
2004: Chen Tse-Ching; Cobbold Stephen P; Fairchild Paul J; Waldmann Herman
Generation of anergic and regulatory T cells following prolonged exposure to a harmless antigen.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):5900-7.
2004: Waldmann Herman; Graca Luis; Cobbold Stephen; Adams Elizabeth; Tone Masahide; Tone Yuki
Regulatory T cells and organ transplantation.
Seminars in immunology 2004;16(2):119-26.
2004: Nolan Kathleen F; Strong Victoria; Soler Dulce; Fairchild Paul J; Cobbold Stephen P; Croxton Ruth; Gonzalo Jose-Angel; Rubio Ana; Wells Meghan; Waldmann Herman
IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2201-9.
2004: Novitzky N; Thomas V; Stubbings H; Hale G; Waldmann H
Radiotherapy-based conditioning is effective immunosuppression for patients undergoing transplantation with T-cell depleted stem cell grafts for severe aplasia.
Cytotherapy 2004;6(5):450-6.
2004: Novitzky N; Thomas V; Hale G; Waldmann H
Campath-1 Abs 'in the bag' for hematological malignancies: the Cape Town experience.
Cytotherapy 2004;6(2):172-81.
2003: Cobbold Stephen P; Nolan Kathleen F; Graca Luis; Castejon Raquel; Le Moine Alain; Frewin Mark; Humm Susan; Adams Elizabeth; Thompson Sara; Zelenika Diana; Paterson Alison; Yates Stephen; Fairchild Paul J; Waldmann Herman
Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms.
Immunological reviews 2003;196():109-24.
2003: Tone Masahide; Tone Yukiko; Adams Elizabeth; Yates Stephen F; Frewin Mark R; Cobbold Stephen P; Waldmann Herman
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15059-64.
2003: Graca Luis; Le Moine Alain; Cobbold Stephen P; Waldmann Herman
Dominant transplantation tolerance. Opinion.
Current opinion in immunology 2003;15(5):499-506.
2003: Cobbold Stephen P; Adams Elizabeth; Graca Luis; Waldmann Herman
Serial analysis of gene expression provides new insights into regulatory T cells.
Seminars in immunology 2003;15(4):209-14.
2003: Waldmann Herman
The new immunosuppression.
Current opinion in chemical biology 2003;7(4):476-80.
2003: Fairchild Paul J; Nolan Kathleen F; Cartland Siân; Graça Luis; Waldmann Herman
Stable lines of genetically modified dendritic cells from mouse embryonic stem cells.
Transplantation 2003;76(3):606-8.
2003: Cobbold Stephen P; Graca Luis; Lin Chun-Yen; Adams Elizabeth; Waldmann Herman
Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance.
Transplant international : official journal of the European Society for Organ Transplantation 2003;16(2):66-75.
2003: Graca Luis; Le Moine Alain; Cobbold Stephen P; Waldmann Herman
Antibody-induced transplantation tolerance: the role of dominant regulation.
Immunologic research 2003;28(3):181-91.
2003: Fairchild Paul J; Nolan Kathleen F; Waldmann Herman
Probing dendritic cell function by guiding the differentiation of embryonic stem cells.
Methods in enzymology 2003;365():169-86.
2002: Novitzky Nicolas; Davison Glenda M; Hale Geoffrey; Waldmann Herman
Immune reconstitution at 6 months following T-cell depleted hematopoietic stem cell transplantation is predictive for treatment outcome.
Transplantation 2002;74(11):1551-9.
2002: Hale G; Slavin S; Goldman J M; Mackinnon S; Giralt S; Waldmann H
Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of nonmyeloablative conditioning?
Bone marrow transplantation 2002;30(12):797-804.
2002: Lin Chun-Yen; Graca Luis; Cobbold Stephen P; Waldmann Herman
Dominant transplantation tolerance impairs CD8+ T cell function but not expansion.
Nature immunology 2002;3(12):1208-13.
2002: Symons Julian A; Adams Elizabeth; Tscharke David C; Reading Patrick C; Waldmann Herman; Smith Geoffrey L
The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model.
The Journal of general virology 2002;83(Pt 11):2833-44.
2002: Lundin Jeanette; Kimby Eva; Björkholm Magnus; Broliden Per-Anders; Celsing Fredrik; Hjalmar Viktoria; Möllgård Lars; Rebello Peppy; Hale Geoff; Waldmann Herman; Mellstedt Håkan; Osterborg Anders
Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL).
Blood 2002;100(3):768-73.
2002: Waldmann Herman
Reprogramming the immune system.
Immunological reviews 2002;185():227-35.
2002: Graca Luis; Cobbold Stephen P; Waldmann Herman
Identification of regulatory T cells in tolerated allografts.
The Journal of experimental medicine 2002;195(12):1641-6.
2002: Graca Luis; Thompson Sara; Lin Chun-Yen; Adams Elizabeth; Cobbold Stephen P; Waldmann Herman
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5558-65.
2002: Tone Masahide; Tone Yukiko; Babik Jennifer M; Lin Chun-Yen; Waldmann Herman
The role of Sp1 and NF-kappa B in regulating CD40 gene expression.
The Journal of biological chemistry 2002;277(11):8890-7.
2002: Zelenika Diana; Adams Elizabeth; Humm Sue; Graca Luis; Thompson Sara; Cobbold Stephen P; Waldmann Herman
Regulatory T cells overexpress a subset of Th2 gene transcripts.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1069-79.
2001: Waldmann H
Therapeutic approaches for transplantation.
Current opinion in immunology 2001;13(5):606-10.
2001: Waldmann H; Cobbold S
Approaching tolerance in transplantation.
International archives of allergy and immunology 2001;126(1):11-22.
2001: Zelenika D; Adams E; Humm S; Lin C Y; Waldmann H; Cobbold S P
The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance.
Immunological reviews 2001;182():164-79.
2001: Waldmann H; Hale G; Cobbold S
Appropriate targets for monoclonal antibodies in the induction of transplantation tolerance.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1409):659-63.
2001: Waldmann H; Cobbold S
Regulating the immune response to transplants. a role for CD4+ regulatory cells?
Immunity 2001;14(4):399-406.
2001: Tone M; Tone Y; Fairchild P J; Wykes M; Waldmann H
Regulation of CD40 function by its isoforms generated through alternative splicing.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1751-6.
2001: Hale G; Cobbold S; Novitzky N; Bunjes D; Willemze R; Prentice H G; Milligan D; MacKinnon S; Waldmann H;
CAMPATH-1 antibodies in stem-cell transplantation.
Cytotherapy 2001;3(3):145-64.
2000: Fairchild P J; Brook F A; Gardner R L; Graça L; Strong V; Tone Y; Tone M; Nolan K F; Waldmann H
Directed differentiation of dendritic cells from mouse embryonic stem cells.
Current biology : CB 2000;10(23):1515-8.
2000: Graca L; Honey K; Adams E; Cobbold S P; Waldmann H
Cutting edge: anti-CD154 therapeutic antibodies induce infectious transplantation tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):4783-6.
2000: Fairchild P J; Waldmann H
Dendritic cells and prospects for transplantation tolerance.
Current opinion in immunology 2000;12(5):528-35.
2000: Fairchild P J; Waldmann H
Extrathymic signals regulate the onset of T cell repertoire selection.
European journal of immunology 2000;30(7):1948-56.
2000: Hale G; Jacobs P; Wood L; Fibbe W E; Barge R; Novitzky N; Toit C; Abrahams L; Thomas V; Bunjes D; Duncker C; Wiesneth M; Selleslag D; Hidajat M; Starobinski M; Bird P; Waldmann H
CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells.
Bone marrow transplantation 2000;26(1):69-76.
2000: Powell M J; Thompson S A; Tone Y; Waldmann H; Tone M
Posttranscriptional regulation of IL-10 gene expression through sequences in the 3'-untranslated region.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):292-6.
2000: Tone M; Powell M J; Tone Y; Thompson S A; Waldmann H
IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):286-91.
2000: Honey K; Cobbold S P; Waldmann H
Dominant tolerance and linked suppression induced by therapeutic antibodies do not depend on Fas-FasL interactions.
Transplantation 2000;69(8):1683-9.
2000: Honey K; Bemelman F; Cobbold S P; Waldmann H
High dose bone marrow transplantation induces deletion of antigen-specific T cells in a Fas-independent manner.
Transplantation 2000;69(8):1676-82.
2000: Davison G M; Novitzky N; Kline A; Thomas V; Abrahams L; Hale G; Waldmann H
Immune reconstitution after allogeneic bone marrow transplantation depleted of T cells.
Transplantation 2000;69(7):1341-7.
2000: Calne R; Moffatt S D; Friend P J; Jamieson N V; Bradley J A; Hale G; Firth J; Bradley J; Smith K G; Waldmann H
Prope tolerance with induction using Campath 1H and low-dose cyclosporin monotherapy in 31 cadaveric renal allograft recipients.
Nippon Geka Gakkai zasshi 2000;101(3):301-6.
2000: Dick A D; Meyer P; James T; Forrester J V; Hale G; Waldmann H; Isaacs J D
Campath-1H therapy in refractory ocular inflammatory disease.
The British journal of ophthalmology 2000;84(1):107-9.
1999: Friend P J; Hale G; Chatenoud L; Rebello P; Bradley J; Thiru S; Phillips J M; Waldmann H
Phase I study of an engineered aglycosylated humanized CD3 antibody in renal transplant rejection.
Transplantation 1999;68(11):1632-7.
1999: Calne R; Moffatt S D; Friend P J; Jamieson N V; Bradley J A; Hale G; Firth J; Bradley J; Smith K G; Waldmann H
Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients.
Transplantation 1999;68(10):1613-6.
1999: Rebello P R; Hale G; Friend P J; Cobbold S P; Waldmann H
Anti-globulin responses to rat and humanized CAMPATH-1 monoclonal antibody used to treat transplant rejection.
Transplantation 1999;68(9):1417-20.
1999: Coles A J; Wing M; Smith S; Coraddu F; Greer S; Taylor C; Weetman A; Hale G; Chatterjee V K; Waldmann H; Compston A
Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis.
Lancet 1999;354(9191):1691-5.
1999: Honey K; Cobbold S P; Waldmann H
CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):4805-10.
1999: Lockwood C M; Elliott J D; Brettman L; Hale G; Rebello P; Frewin M; Ringler D; Merrill C; Waldmann H
Anti-adhesion molecule therapy as an interventional strategy for autoimmune inflammation.
Clinical immunology (Orlando, Fla.) 1999;93(2):93-106.
1999: Tone M; Nolan K F; Walsh L A; Tone Y; Thompson S A; Waldmann H
Structure and chromosomal location of mouse and human CD52 genes.
Biochimica et biophysica acta 1999;1446(3):334-40.
1999: Coles A J; Wing M G; Molyneux P; Paolillo A; Davie C M; Hale G; Miller D; Waldmann H; Compston A
Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis.
Annals of neurology 1999;46(3):296-304.
1999: Babik J M; Adams E; Tone Y; Fairchild P J; Tone M; Waldmann H
Expression of murine IL-12 is regulated by translational control of the p35 subunit.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):4069-78.
1999: Gilliland L K; Walsh L A; Frewin M R; Wise M P; Tone M; Hale G; Kioussis D; Waldmann H
Elimination of the immunogenicity of therapeutic antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3663-71.
1999: Novitzky N; Thomas V; Hale G; Waldmann H
Ex vivo depletion of T cells from bone marrow grafts with CAMPATH-1 in acute leukemia: graft-versus-host disease and graft-versus-leukemia effect.
Transplantation 1999;67(4):620-6.
1999: Wise M; Zelenika D; Bemelman F; Latinne D; Bazin H; Cobbold S; Waldmann H
CD4 T cells can reject major histocompatibility complex class I-incompatible skin grafts.
European journal of immunology 1999;29(1):156-67.
1999: Tone M; Diamond L E; Walsh L A; Tone Y; Thompson S A; Shanahan E M; Logan J S; Waldmann H
High level transcription of the complement regulatory protein CD59 requires an enhancer located in intron 1.
The Journal of biological chemistry 1999;274(2):710-6.
1999: Honey K; Cobbold S P; Waldmann H
Dominant regulation: a common mechanism of monoclonal antibody induced tolerance?
Immunologic research 1999;20(1):1-14.
1998: Hale G; Zhang M J; Bunjes D; Prentice H G; Spence D; Horowitz M M; Barrett A J; Waldmann H
Improving the outcome of bone marrow transplantation by using CD52 monoclonal antibodies to prevent graft-versus-host disease and graft rejection.
Blood 1998;92(12):4581-90.
1998: Wise M P; Bemelman F; Cobbold S P; Waldmann H
Linked suppression of skin graft rejection can operate through indirect recognition.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):5813-6.
1998: Cobbold S; Waldmann H
Infectious tolerance.
Current opinion in immunology 1998;10(5):518-24.
1998: Isaacs J D; Greenwood J; Waldmann H
Therapy with monoclonal antibodies. II. The contribution of Fc gamma receptor binding and the influence of C(H)1 and C(H)3 domains on in vivo effector function.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3862-9.
1998: Zelenika D; Adams E; Mellor A; Simpson E; Chandler P; Stockinger B; Waldmann H; Cobbold S P
Rejection of H-Y disparate skin grafts by monospecific CD4+ Th1 and Th2 cells: no requirement for CD8+ T cells or B cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1868-74.
1998: Nolan K F; Greaves D R; Waldmann H
The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci.
Genomics 1998;51(1):161-3.
1998: Calne R; Friend P; Moffatt S; Bradley A; Hale G; Firth J; Bradley J; Smith K; Waldmann H
Prope tolerance, perioperative campath 1H, and low-dose cyclosporin monotherapy in renal allograft recipients.
Lancet 1998;351(9117):1701-2.
1998: Dick A D; Duncan L; Hale G; Waldmann H; Isaacs J
Neutralizing TNF-alpha activity modulates T-cell phenotype and function in experimental autoimmune uveoretinitis.
Journal of autoimmunity 1998;11(3):255-64.
1998: Hale G; Waldmann H
Risks of developing Epstein-Barr virus-related lymphoproliferative disorders after T-cell-depleted marrow transplants. CAMPATH Users.
Blood 1998;91(8):3079-83.
1998: Bemelman F; Honey K; Adams E; Cobbold S; Waldmann H
Bone marrow transplantation induces either clonal deletion or infectious tolerance depending on the dose.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2645-8.
1998: Elliott J D; Lockwood C M; Hale G; Waldmann H
Semi-specific immuno-absorption and monoclonal antibody therapy in ANCA positive vasculitis: experience in four cases.
Autoimmunity 1998;28(3):163-71.
1998: Waldmann H; Bemelman F; Cobbold S
Tolerance induction with CD4 monoclonal antibodies.
Novartis Foundation symposium 1998;215():146-52; discussion 152-8, 186-90.
1998: Waldmann H; Cobbold S
How do monoclonal antibodies induce tolerance? A role for infectious tolerance?
Annual review of immunology 1998;16():619-44.
1997: Tone M; Thompson S A; Tone Y; Fairchild P J; Waldmann H
Regulation of IL-18 (IFN-gamma-inducing factor) gene expression.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):6156-63.
1997: Isaacs J D; Burrows N; Wing M; Keogan M T; Rebello P R; Watts R A; Pye R J; Norris P; Hazelman B L; Hale G; Waldmann H
Humanized anti-CD4 monoclonal antibody therapy of autoimmune and inflammatory disease.
Clinical and experimental immunology 1997;110(2):158-66.
1997: Scully R; Cobbold S P; Mellor A L; Wissing M; Arnold B; Waldmann H
A role for Th2 cytokines in the suppression of CD8+ T cell-mediated graft rejection.
European journal of immunology 1997;27(7):1663-70.
1997: Davies J D; Cobbold S P; Waldmann H
Strain variation in susceptibility to monoclonal antibody-induced transplantation tolerance.
Transplantation 1997;63(11):1570-3.
1996: Lockwood C M; Thiru S; Stewart S; Hale G; Isaacs J; Wraight P; Elliott J; Waldmann H
Treatment of refractory Wegener's granulomatosis with humanized monoclonal antibodies.
QJM : monthly journal of the Association of Physicians 1996;89(12):903-12.
1996: Wing M G; Moreau T; Greenwood J; Smith R M; Hale G; Isaacs J; Waldmann H; Lachmann P J; Compston A
Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells.
The Journal of clinical investigation 1996;98(12):2819-26.
1996: Isaacs J D; Wing M G; Greenwood J D; Hazleman B L; Hale G; Waldmann H
A therapeutic human IgG4 monoclonal antibody that depletes target cells in humans.
Clinical and experimental immunology 1996;106(3):427-33.
1996: Marshall S E; Cobbold S P; Davies J D; Martin G M; Phillips J M; Waldmann H
Tolerance and suppression in a primed immune system.
Transplantation 1996;62(11):1614-21.
1996: Chen Z K; Cobbold S P; Waldmann H; Metcalfe S
Amplification of natural regulatory immune mechanisms for transplantation tolerance.
Transplantation 1996;62(9):1200-6.
1996: Moreau T; Coles A; Wing M; Thorpe J; Miller D; Moseley I; Issacs J; Hale G; Clayton D; Scolding N; Waldmann H; Compston A
CAMPATH-IH in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 1996;1(6):357-65.
1996: Davies J D; Martin G; Phillips J; Marshall S E; Cobbold S P; Waldmann H
T cell regulation in adult transplantation tolerance.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):529-33.
1996: Tone Y; Thompson S A; Babik J M; Nolan K F; Tone M; Raven C; Waldmann H
Structure and chromosomal location of the mouse interleukin-12 p35 and p40 subunit genes.
European journal of immunology 1996;26(6):1222-7.
1996: Davies J D; Leong L Y; Mellor A; Cobbold S P; Waldmann H
T cell suppression in transplantation tolerance through linked recognition.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(10):3602-7.
1996: Hale G; Waldmann H
Recent results using CAMPATH-1 antibodies to control GVHD and graft rejection.
Bone marrow transplantation 1996;17(3):305-8.
1996: Cobbold S P; Adams E; Marshall S E; Davies J D; Waldmann H
Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8.
Immunological reviews 1996;149():5-33.
1996: Moreau T; Coles A; Wing M; Isaacs J; Hale G; Waldmann H; Compston A
Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis.
Brain : a journal of neurology 1996;119 ( Pt 1)():225-37.
1995: Diamond L E; McCurry K R; Oldham E R; Tone M; Waldmann H; Platt J L; Logan J S
Human CD59 expressed in transgenic mouse hearts inhibits the activation of complement.
Transplant immunology 1995;3(4):305-12.
1995: Brons I G; Davies H S; Watson C J; Cobbold S P; Waldmann H; Calne R Y
Substantial peripheral T-cell depletion before grafting is beneficial in islet transplantation.
Transplantation proceedings 1995;27(6):3181.
1995: Routledge E G; Falconer M E; Pope H; Lloyd I S; Waldmann H
The effect of aglycosylation on the immunogenicity of a humanized therapeutic CD3 monoclonal antibody.
Transplantation 1995;60(8):847-53.
1995: Wing M G; Waldmann H; Isaacs J; Compston D A; Hale G
Ex-vivo whole blood cultures for predicting cytokine-release syndrome: dependence on target antigen and antibody isotype.
Therapeutic immunology 1995;2(4):183-90.
1995: Kooyman D L; Byrne G W; McClellan S; Nielsen D; Tone M; Waldmann H; Coffman T M; McCurry K R; Platt J L; Logan J S
In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium.
Science (New York, N.Y.) 1995;269(5220):89-92.
1995: Watson C J; Davies H F; Cobbold S P; Rasmussen A; Rebello P R; Thiru S; Waldmann H; Calne R Y; Metcalfe S M
CD4 and CD8 monoclonal antibody therapy in the dog: strategies to induce tolerance to renal allografts.
Transplantation proceedings 1995;27(1):123-4.
1995: Brons I G; Davies H F; Rasmussen A; Watson C J; Thiru S; Cobbold S P; Waldmann H; Calne R Y
Islet allografting in the dog model: potential therapies for tolerance induction.
Transplantation proceedings 1995;27(1):609-10.
1995: Newman D K; Isaacs J D; Watson P G; Meyer P A; Hale G; Waldmann H
Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody, CAMPATH-1H.
Eye (London, England) 1995;9 ( Pt 5)():564-9.
1994: Scully R; Qin S; Cobbold S; Waldmann H
Mechanisms in CD4 antibody-mediated transplantation tolerance: kinetics of induction, antigen dependency and role of regulatory T cells.
European journal of immunology 1994;24(10):2383-92.
1994: Waldmann H; Cobbold S; Hale G
What can be done to prevent graft versus host disease?
Current opinion in immunology 1994;6(5):777-83.
1994: Greenwood J; Gorman S D; Routledge E G; Lloyd I S; Waldmann H
Engineering multiple-domain forms of the therapeutic antibody CAMPATH-1H: effects on complement lysis.
Therapeutic immunology 1994;1(5):247-55.
1994: Chen Z; Cobbold S; Waldmann H; Metcalfe S
Combined use of RS61443 with CD4 and CD8 MAbs to generate tolerance to skin xenografts from rat to mouse.
Transplantation proceedings 1994;26(4):2433-4.
1994: Davies H S; Cobbold S P; Watson C J; Metcalfe S M; Rebello P R; Thiru S; McNair R; Rasmussen A; Waldmann H; Calne R Y
Production, selection, and testing of monoclonal antibodies to canine leukocytes in the dog kidney allograft model.
Transplantation proceedings 1994;26(4):1941-2.
1994: Moreau T; Thorpe J; Miller D; Moseley I; Hale G; Waldmann H; Clayton D; Wing M; Scolding N; Compston A
Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis.
Lancet 1994;344(8918):298-301.
1994: Chen Z; Cobbold S P; Waldmann H; Metcalfe S M
Tolerance induction in concordant heart-xenografted mice by CD4 and CD8 monoclonal antibodies.
Transplantation proceedings 1994;26(3):1199-200.
1994: Kooyman D; Byrne G; McClellan S; Nielsen D; Kagan D; Coffman T; Masahide T; Waldmann H; Platt J; Logan J
Erythroid-specific expression of human CD59 and transfer to vascular endothelial cells.
Transplantation proceedings 1994;26(3):1241.
1994: Diamond L E; Oldham E R; Platt J L; Waldmann H; Tone M; Walsh L A; Logan J S
Cell- and tissue-specific expression of a human CD59 minigene in transgenic mice.
Transplantation proceedings 1994;26(3):1239.
1994: Hale G; Waldmann H
Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies. Results of matched sibling transplants for malignant diseases.
Bone marrow transplantation 1994;13(5):597-611.
1994: Brons I G; Davies H S; Makisalo H; Rasmussen A; Cobbold S P; Waldmann H; Calne R Y
Transplantation of immunomodulated dog islets.
Transplantation proceedings 1994;26(2):754.
1994: Gorman S D; Frewin M R; Cobbold S P; Waldmann H
Isolation and expression of cDNA encoding the canine CD4 and CD8 alpha antigens.
Tissue antigens 1994;43(3):184-8.
1994: Watson C J; Cobbold S P; Davies H S; Rebello P R; Thiru S; McNair R; Rasmussen A; Waldmann H; Calne R Y; Metcalfe S M
Immunosuppression of canine renal allograft recipients by CD4 and CD8 monoclonal antibodies.
Tissue antigens 1994;43(3):155-62.
1994: Watson C J; Cobbold S P; Davies H F; Rebello P R; Waldmann H; Calne R Y; Metcalfe S M
CD4 and CD8 monoclonal antibody therapy in canine renal allografts.
Transplant international : official journal of the European Society for Organ Transplantation 1994;7 Suppl 1():S322-4.
1994: Hale G; Waldmann H
CAMPATH-1 monoclonal antibodies in bone marrow transplantation.
Journal of hematotherapy 1994;3(1):15-31.
1993: Parish N M; Hutchings P R; Waldmann H; Cooke A
Tolerance to IDDM induced by CD4 antibodies in nonobese diabetic mice is reversed by cyclophosphamide.
Diabetes 1993;42(11):1601-5.
1993: Watson C J; Cobbold S P; Davies H S; Rebello P R; Waldmann H; Calne R Y; Metcalfe S M
CD4 and CD8 monoclonal antibody therapy: strategies to prolong renal allograft survival in the dog.
The British journal of surgery 1993;80(11):1389-92.
1993: Waldmann H; Cobbold S
Monoclonal antibodies for the induction of transplantation tolerance.
Current opinion in immunology 1993;5(5):753-8.
1993: Xia M Q; Hale G; Waldmann H
Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen.
Molecular immunology 1993;30(12):1089-96.
1993: Xia M Q; Hale G; Lifely M R; Ferguson M A; Campbell D; Packman L; Waldmann H
Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis.
The Biochemical journal 1993;293 ( Pt 3)():633-40.
1993: Lockwood C M; Thiru S; Isaacs J D; Hale G; Waldmann H
Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy.
Lancet 1993;341(8861):1620-2.
1993: Greenwood J; Clark M; Waldmann H
Structural motifs involved in human IgG antibody effector functions.
European journal of immunology 1993;23(5):1098-104.
1993: Watts R A; Isaacs J D; Hale G; Hazleman B L; Waldmann H
CAMPATH-1H in inflammatory arthritis.
Clinical and experimental rheumatology 1993;11 Suppl 8():S165-7.
1993: Waldmann H; Cobbold S P; Isaacs J; Hale G; Hazleman B; Cooke A; Lockwood M
Reprogramming the immune system: a possible therapeutic approach to established autoimmune disease.
Clinical and experimental rheumatology 1993;11 Suppl 8():S137.
1993: Watson C J; Davies H S; Metcalfe S M; Cobbold S P; Rebello P R; Collier D S; Waldmann H; Calne R Y
CD4 monoclonal antibodies in the preclinical dog renal allograft model.
Transplantation proceedings 1993;25(1 Pt 1):804-6.
1993: Chen Z; Cobbold S; Waldmann H; Metcalfe S
Stability of tolerance in mice generated by CD4 and CD8 monoclonal antibody treatment: cell transfer experiments.
Transplantation proceedings 1993;25(1 Pt 1):790-1.
1993: Bolt S; Routledge E; Lloyd I; Chatenoud L; Pope H; Gorman S D; Clark M; Waldmann H
The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties.
European journal of immunology 1993;23(2):403-11.
1993: Qin S; Cobbold S P; Pope H; Elliott J; Kioussis D; Davies J; Waldmann H
"Infectious" transplantation tolerance.
Science (New York, N.Y.) 1993;259(5097):974-7.
1993: Waldmann H; Qin S; Cobbold S P
Monoclonal antibodies for the therapeutic induction of tolerance.
Immunology series 1993;59():85-99.
1992: Waldmann H; Cobbold S P; Wraith D; Isaacs J
Therapeutic immunosuppression of T cells.
Current opinion in biotechnology 1992;3(6):668-74.
1992: Leong L Y; Qin S; Cobbold S P; Waldmann H
Classical transplantation tolerance in the adult: the interaction between myeloablation and immunosuppression.
European journal of immunology 1992;22(11):2825-30.
1992: Walsh L A; Tone M; Thiru S; Waldmann H
The CD59 antigen--a multifunctional molecule.
Tissue antigens 1992;40(5):213-20.
1992: Cobbold S P; Qin S; Leong L Y; Martin G; Waldmann H
Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies.
Immunological reviews 1992;129():165-201.
1992: Tone M; Walsh L A; Waldmann H
Gene structure of human CD59 and demonstration that discrete mRNAs are generated by alternative polyadenylation.
Journal of molecular biology 1992;227(3):971-6.
1992: Isaacs J D; Watts R A; Hazleman B L; Hale G; Keogan M T; Cobbold S P; Waldmann H
Humanised monoclonal antibody therapy for rheumatoid arthritis.
Lancet 1992;340(8822):748-52.
1992: Hutchings P; O'Reilly L; Parish N M; Waldmann H; Cooke A
The use of a non-depleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice.
European journal of immunology 1992;22(7):1913-8.
1992: Brons I G; Tavora P F; Cobbold S P; Davies H S; Waldmann H; Calne R Y
Synergistic monoclonal antibodies for in vitro immunomodulation of dog islets.
Transplantation proceedings 1992;24(3):1032-3.
1992: Isaacs J D; Clark M R; Greenwood J; Waldmann H
Therapy with monoclonal antibodies. An in vivo model for the assessment of therapeutic potential.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(10):3062-71.
1992: Chen Z; Cobbold S; Metcalfe S; Waldmann H
Tolerance in the mouse to major histocompatibility complex-mismatched heart allografts, and to rat heart xenografts, using monoclonal antibodies to CD4 and CD8.
European journal of immunology 1992;22(3):805-10.
1992: Brons I G; Champeney R; Cobbold S P; Davies H S; Waldmann H; Calne R Y
Immunomodulation of dog islets using a cocktail of monoclonal antibodies.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S484-6.
1991: Routledge E G; Lloyd I; Gorman S D; Clark M; Waldmann H
A humanized monovalent CD3 antibody which can activate homologous complement.
European journal of immunology 1991;21(11):2717-25.
1991: Friend P J; Waldmann H; Hale G; Cobbold S; Rebello P; Thiru S; Jamieson N V; Johnston P S; Calne R Y
Reversal of allograft rejection using the monoclonal antibody, Campath-1G.
Transplantation proceedings 1991;23(4):2253-4.
1991: Xia M Q; Tone M; Packman L; Hale G; Waldmann H
Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone.
European journal of immunology 1991;21(7):1677-84.
1991: Gorman S D; Clark M R; Routledge E G; Cobbold S P; Waldmann H
Reshaping a therapeutic CD4 antibody.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4181-5.
1991: Walsh L A; Tone M; Waldmann H
Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement.
European journal of immunology 1991;21(3):847-50.
1991: Friend P J; Waldmann H; Cobbold S; Tighe H; Rebello P; Wight D; Gore S; Pollard S; Lim S; Johnston P
The anti-IL-2 receptor monoclonal antibody YTH-906 in liver transplantation.
Transplantation proceedings 1991;23(1 Pt 2):1390-2.
1991: Varey A M; Hutchings P; O'Reilly L; Hussell T; Waldmann H; Simpson E; Cooke A
The development of insulin-dependent diabetes mellitus in non-obese diabetic mice: the role of CD4+ and CD8+ T cells.
Biochemical Society transactions 1991;19(1):187-91.
1990: Cobbold S P; Martin G; Waldmann H
The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies.
European journal of immunology 1990;20(12):2747-55.
1990: Qin S X; Wise M; Cobbold S P; Leong L; Kong Y C; Parnes J R; Waldmann H
Induction of tolerance in peripheral T cells with monoclonal antibodies.
European journal of immunology 1990;20(12):2737-45.
1990: Cobbold S P; Qin S X; Waldmann H
Reprogramming the immune system for tolerance with monoclonal antibodies.
Seminars in immunology 1990;2(6):377-87.
1990: Meri S; Morgan B P; Davies A; Daniels R H; Olavesen M G; Waldmann H; Lachmann P J
Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers.
Immunology 1990;71(1):1-9.
1990: Mathieson P W; Cobbold S P; Hale G; Clark M R; Oliveira D B; Lockwood C M; Waldmann H
Monoclonal-antibody therapy in systemic vasculitis.
The New England journal of medicine 1990;323(4):250-4.
1990: Hutchings P R; Simpson E; O'Reilly L A; Lund T; Waldmann H; Cooke A
The involvement of Ly2+ T cells in beta cell destruction.
Journal of autoimmunity 1990;3 Suppl 1():101-9.
1990: Hale G; Xia M Q; Tighe H P; Dyer M J; Waldmann H
The CAMPATH-1 antigen (CDw52).
Tissue antigens 1990;35(3):118-27.
1990: Bindon C I; Hale G; Waldmann H
Complement activation by immunoglobulin does not depend solely on C1q binding.
European journal of immunology 1990;20(2):277-81.
1990: Cobbold S P; Hale G; Clark M R; Waldmann H
Purging in auto- and allografts: monoclonal antibodies which use human complement and other natural effector mechanisms.
Progress in clinical and biological research 1990;333():139-51; discussion 152-4.
1989: Brüggemann M; Winter G; Waldmann H; Neuberger M S
The immunogenicity of chimeric antibodies.
The Journal of experimental medicine 1989;170(6):2153-7.
1989: Brüggemann M; Caskey H M; Teale C; Waldmann H; Williams G T; Surani M A; Neuberger M S
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(17):6709-13.
1989: Friend P J; Hale G; Waldmann H; Gore S; Thiru S; Joysey V; Evans D B; Calne R Y
Campath-1M--prophylactic use after kidney transplantation. A randomized controlled clinical trial.
Transplantation 1989;48(2):248-53.
1989: Dyer M J; Hale G; Hayhoe F G; Waldmann H
Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype.
Blood 1989;73(6):1431-9.
1989: Brüggemann M; Teale C; Clark M; Bindon C; Waldmann H
A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3145-50.
1989: Qin S X; Cobbold S; Benjamin R; Waldmann H
Induction of classical transplantation tolerance in the adult.
The Journal of experimental medicine 1989;169(3):779-94.
1989: Clark M; Bindon C; Dyer M; Friend P; Hale G; Cobbold S; Calne R; Waldmann H
The improved lytic function and in vivo efficacy of monovalent monoclonal CD3 antibodies.
European journal of immunology 1989;19(2):381-8.
1989: Zamoyska R; Waldmann H; Matzinger P
Peripheral tolerance mechanisms prevent the development of autoreactive T cells in chimeras grafted with two minor incompatible thymuses.
European journal of immunology 1989;19(1):111-7.
1989: Waldmann H; Cobbold S P; Qin S; Benjamin R J; Wise M
Tolerance induction in the adult using monoclonal antibodies to CD4, CD8, and CD11a (LFA-1).
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():885-92.
1989: Waldmann H
Manipulation of T-cell responses with monoclonal antibodies.
Annual review of immunology 1989;7():407-44.
1988: Waldmann H
Immunosuppression with monoclonal antibodies: some speculations about tolerance in the context of tissue grafting.
Transplantation proceedings 1988;20(6 Suppl 8):46-52.
1988: Hale G; Dyer M J; Clark M R; Phillips J M; Marcus R; Riechmann L; Winter G; Waldmann H
Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H.
Lancet 1988;2(8625):1394-9.
1988: Gilliland L K; Clark M R; Waldmann H
Universal bispecific antibody for targeting tumor cells for destruction by cytotoxic T cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7719-23.
1988: Bindon C I; Hale G; Waldmann H
Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.
European journal of immunology 1988;18(10):1507-14.
1988: Bindon C I; Hale G; Brüggemann M; Waldmann H
Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q.
The Journal of experimental medicine 1988;168(1):127-42.
1988: Benjamin R J; Qin S X; Wise M P; Cobbold S P; Waldmann H
Mechanisms of monoclonal antibody-facilitated tolerance induction: a possible role for the CD4 (L3T4) and CD11a (LFA-1) molecules in self-non-self discrimination.
European journal of immunology 1988;18(7):1079-88.
1988: Hale G; Cobbold S; Waldmann H
T cell depletion with CAMPATH-1 in allogeneic bone marrow transplantation.
Transplantation 1988;45(4):753-9.
1988: Brüggemann M; Delmastro-Galfrè P; Waldmann H; Calabi F
Sequence of a rat immunoglobulin gamma 2c heavy chain constant region cDNA: extensive homology to mouse gamma 3.
European journal of immunology 1988;18(2):317-9.
1988: Tighe H; Friend P J; Collier S J; Decurtins M; Lim S; Cobbold S P; Thiru S; Calne R Y; Waldmann H
Delayed allograft rejection in primates treated with anti-IL-2 receptor monoclonal antibody Campath-6.
Transplantation 1988;45(1):226-8.
1988: Clark M; Gilliland L; Waldmann H
The potential of hybrid antibodies secreted by hybrid-hybridomas in tumour therapy.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1988;2():15-7.
1987: Clark M R; Waldmann H
T-cell killing of target cells induced by hybrid antibodies: comparison of two bispecific monoclonal antibodies.
Journal of the National Cancer Institute 1987;79(6):1393-401.
1987: Tighe H; Clark M; Waldmann H
Blocking of cytotoxic T cell function by monoclonal antibodies against the CD45 antigen (T200/leukocyte-common antigen).
Transplantation 1987;44(6):818-23.
1987: Brüggemann M; Williams G T; Bindon C I; Clark M R; Walker M R; Jefferis R; Waldmann H; Neuberger M S
Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.
The Journal of experimental medicine 1987;166(5):1351-61.
1987: Hale G; Cobbold S P; Waldmann H; Easter G; Matejtschuk P; Coombs R R
Isolation of low-frequency class-switch variants from rat hybrid myelomas.
Journal of immunological methods 1987;103(1):59-67.
1987: Friend P J; Tighe H; Lim S; Collier D S; Decurtins M; Gilliland L K; Thiru S; Calne R; Waldmann H
The use of monoclonal antibodies against activated human T cells following renal allografting in the baboon.
Transplantation proceedings 1987;19(5):4317-8.
1987: Qin S; Cobbold S; Tighe H; Benjamin R; Waldmann H
CD4 monoclonal antibody pairs for immunosuppression and tolerance induction.
European journal of immunology 1987;17(8):1159-65.
1987: Bindon C I; Hale G; Hughes-Jones N; Gorick B; Waldmann H
Synergistic complement lysis by monoclonal antibodies to the human leukocyte common antigen requires both the classical and alternative pathways.
Molecular immunology 1987;24(6):587-94.
1987: Friend P J; Calne R Y; Hale G; Waldmann H; Evans D B; Rolles K; Thiru S; Gore S
Prophylactic use of an antilymphocyte monoclonal antibody following renal transplantation: a randomized controlled trial.
Transplantation proceedings 1987;19(1 Pt 3):1898-900.
1987: Waldmann H; Cobbold S; Qin S; Benjamin R; Nash T; Welsh J; Tarnesby G
Monoclonal antibodies for the depletion of specific subpopulations of lymphocytes.
Ciba Foundation symposium 1987;129():194-208.
1986: Hale G; Waldmann H; Friend P; Calne R
Pilot study of CAMPATH-1, a rat monoclonal antibody that fixes human complement, as an immunosuppressant in organ transplantation.
Transplantation 1986;42(3):308-11.
1986: Benjamin R J; Cobbold S P; Clark M R; Waldmann H
Tolerance to rat monoclonal antibodies. Implications for serotherapy.
The Journal of experimental medicine 1986;163(6):1539-52.
1984: Matzinger P; Zamoyska R; Waldmann H
Self tolerance is H-2-restricted.
Nature 1984;308(5961):738-41.
1983: Hoang T; Gilmore D; Metcalf D; Cobbold S; Watt S; Clark M; Furth M; Waldmann H
Separation of hemopoietic cells from adult mouse marrow by use of monoclonal antibodies.
Blood 1983;61(3):580-8.

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