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Charles Waldren

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Hongning Zhou; An Xu; Joseph A Gillispie; Charles A Waldren; Tom K Hei
Quantification of CD59- mutants in human-hamster hybrid (AL) cells by flow cytometry.
Burton G Bennett; Charles A Waldren
60 years since atomic bombings of Hiroshima and Nagasaki: radiation effects research at RERF.
Charles A Waldren; Diane B Vannais; Akiko M Ueno
A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO.

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2006: Hongning Zhou; An Xu; Joseph A Gillispie; Charles A Waldren; Tom K Hei
Quantification of CD59- mutants in human-hamster hybrid (AL) cells by flow cytometry.
Mutation research 2006;594(1-2):113-9.
2005: Burton G Bennett; Charles A Waldren
60 years since atomic bombings of Hiroshima and Nagasaki: radiation effects research at RERF.
Radiation research 2005;164(3):235-6.
2004: Charles A Waldren; Diane B Vannais; Akiko M Ueno
A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO.
Mutation research 2004;551(1-2):255-65.
2004: Catherine Sauvaget; Fumiyoshi Kasagi; Charles A Waldren
Dietary factors and cancer mortality among atomic-bomb survivors.
Mutation research 2004;551(1-2):145-52.
2004: Charles A Waldren
Classical radiation biology dogma, bystander effects and paradigm shifts.
Human & experimental toxicology 2004;23(2):95-100.
2004: Hongning Zhou; Gerhard Randers-Pehrson; Charles A Waldren; Tom K Hei
Radiation-induced bystander effect and adaptive response in mammalian cells.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) 2004;34(6):1368-72.
2003: Marek Lenarczyk; Akiko M Ueno; Diane B Vannais; SUSAN KRAEMER; A Kronenberg; J C Roberts; K Tatsumi; Tom K Hei; Charles A Waldren
The "pro-drug" RibCys decreases the mutagenicity of high-LET radiation in cultured mammalian cells.
Radiation research 2003;160(5):579-83.
2002: Akiko M Ueno; Diane B Vannais; Marek Lenarczyk; Charles A Waldren
Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions.
Journal of radiation research 2002;43 Suppl():S245-9.
2002: Hongning Zhou; Gerhard Randers-Pehrson; Masao Suzuki; Charles A Waldren; Tom K Hei
Genotoxic damage in non-irradiated cells: contribution from the bystander effect.
Radiation protection dosimetry 2002;99(1-4):227-32.
2001: Hongning Zhou; Masao Suzuki; Gerhard Randers-Pehrson; Diane B Vannais; Guoying Chen; James E Trosko; Charles A Waldren; Tom K Hei
Radiation risk to low fluences of alpha particles may be greater than we thought.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(25):14410-5.
2001: Sylvain V Costes; Rainer K Sachs; Lynn Hlatky; Diane B Vannais; Charles A Waldren; B Fouladi
Large-mutation spectra induced at hemizygous loci by low-LET radiation: evidence for intrachromosomal proximity effects.
Radiation research 2001;156(5 Pt 1):545-57.
2001: SUSAN KRAEMER; Diane B Vannais; A Kronenberg; Akiko M Ueno; Charles A Waldren
Gamma-ray mutagenesis studies in a new human-hamster hybrid, A(L)CD59(+/-), which has two human chromosomes 11 but is hemizygous for the CD59 gene.
Radiation research 2001;156(1):10-9.
2001: Charles A Waldren; Diane B Vannais; Megan S Knowlton; K K Domenico; CJ Smith; DJ Doolittle
The role of glutathione in the toxicity of smoke condensates from cigarettes that burn or heat tobacco.
Free radical biology & medicine 2001;30(12):1400-6.
2001: Su Xian Liu; Mohammad Athar; I Lippai; Charles A Waldren; Tom K Hei
Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1643-8.
2001: Alexandra Davies; Diane B Vannais; B A Fernie; A B Wilson; Deborah Gustafson; C Willers; Charles A Waldren
An aberrant form of CD59 derived from HeLa cells.
Experimental and clinical immunogenetics 2001;18(2):71-9.
2000: B Fouladi; Charles A Waldren; Bjorn Rydberg; Priscilla K Cooper
Comparison of repair of DNA double-strand breaks in identical sequences in primary human fibroblast and immortal hamster-human hybrid cells harboring a single copy of human chromosome 11.
Radiation research 2000;153(6):795-804.
2000: SUSAN KRAEMER; A Kronenberg; Akiko M Ueno; Charles A Waldren
Measuring the spectrum of mutation induced by nitrogen ions and protons in the human-hamster hybrid cell line A(L)C.
Radiation research 2000;153(6):743-51.
2000: Daniel L Gustafson; H R Franz; Akiko M Ueno; CJ Smith; DJ Doolittle; Charles A Waldren
Vanillin (3-methoxy-4-hydroxybenzaldehyde) inhibits mutation induced by hydrogen peroxide, N-methyl-N-nitrosoguanidine and mitomycin C but not (137)Cs gamma-radiation at the CD59 locus in human-hamster hybrid A(L) cells.
Mutagenesis 2000;15(3):207-13.
2000: Hongning Zhou; Gerhard Randers-Pehrson; Charles A Waldren; Diane B Vannais; Eric J Hall; Tom K Hei
Induction of a bystander mutagenic effect of alpha particles in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2099-104.
1999: Charles A Waldren
Adaptive response induced by low levels of radiation. Summary and comments.
Human & experimental toxicology 1999;18(7):452-3.
1999: A B Wilson; David J Seilly; C Willers; Diane B Vannais; M McGraw; Charles A Waldren; Tom K Hei; Alexandra Davies
Antigen S1, encoded by the MIC1 gene, is characterized as an epitope of human CD59, enabling measurement of mutagen-induced intragenic deletions in the AL cell system.
Somatic cell and molecular genetics 1999;25(3):147-57.
1999: LJ Wu; Gerhard Randers-Pehrson; A Xu; Charles A Waldren; Charles R Geard; Zengliang Yu; Tom K Hei
Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):4959-64.
1999: Charles A Waldren; Akiko M Ueno; B K Schaeffer; Sheryl G Wood; Peter R Sinclair; DJ Doolittle; CJ Smith; W F Harvey; M L Shibuya; Daniel L Gustafson; Diane B Vannais; T T Puck; J F Sinclair
Mutant yields and mutational spectra of the heterocyclic amines MeIQ and PhIP at the S1 locus of human-hamster AL cells with activation by chick embryo liver (CELC) co-cultures.
Mutation research 1999;425(1):29-46.
1998: Tom K Hei; Su Xian Liu; Charles A Waldren
Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(14):8103-7.
1998: Charles A Waldren; Diane B Vannais; R Drabek; Deborah Gustafson; SUSAN KRAEMER; Marek Lenarczyk; A Kronenberg; Tom K Hei; Akiko M Ueno
Analysis of mutant quantity and quality in human-hamster hybrid AL and AL-179 cells exposed to 137Cs-gamma or HZE-Fe ions.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) 1998;22(4):579-85.
1998: A Christian; Elizabeth A McNiel; J Robinson; R Drabek; Susan M LaRue; Charles A Waldren; J Bedford
A versatile image analysis approach for simultaneous chromosome identification and localization of FISH probes.
Cytogenetics and cell genetics 1998;82(3-4):172-9.
1997: SUSAN KRAEMER; Charles A Waldren
Chromosomal mutations and chromosome loss measured in a new human-hamster hybrid cell line, ALC: studies with colcemid, ultraviolet irradiation, and 137Cs gamma-rays.
Mutation research 1997;379(2):151-66.
1997: Tom K Hei; LJ Wu; Su Xian Liu; Diane B Vannais; Charles A Waldren; Gerhard Randers-Pehrson
Mutagenic effects of a single and an exact number of alpha particles in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3765-70.
1997: Daniel L Gustafson; B K Trotter; D Snead; Charles A Waldren
Expression of human O6-methyl guanine methyl transferase (MGMT) in post replication repair (PRR) deficient CHO-UV-1 cells: compensation for hypersensitivity to methylating and ethylating agents but not to mitomycin C.
Somatic cell and molecular genetics 1997;23(1):9-17.
1996: A M Ueno; Diane B Vannais; Daniel L Gustafson; J C Wong; Charles A Waldren
A low, adaptive dose of gamma-rays reduced the number and altered the spectrum of S1- mutants in human-hamster hybrid AL cells.
Mutation research 1996;358(2):161-9.
1996: Daniel L Gustafson; Howard D Beall; E M Bolton; David Ross; Charles A Waldren
Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones.
Molecular pharmacology 1996;50(4):728-35.
1996: L X Zhu; Charles A Waldren; D Vannias; Tom K Hei
Cellular and molecular analysis of mutagenesis induced by charged particles of defined linear energy transfer.
Radiation research 1996;145(3):251-9.
1995: S M McGuinness; M L Shibuya; A M Ueno; Diane B Vannais; Charles A Waldren
Mutant quantity and quality in mammalian cells (AL) exposed to cesium-137 gamma radiation: effect of caffeine.
Radiation research 1995;142(3):247-55.
1995: A Kronenberg; S Gauny; K Criddle; Diane B Vannais; A Ueno; SUSAN KRAEMER; Charles A Waldren
Heavy ion mutagenesis: linear energy transfer effects and genetic linkage.
Radiation and environmental biophysics 1995;34(2):73-8.
1994: Tom K Hei; L X Zhu; Diane B Vannais; Charles A Waldren
Molecular analysis of mutagenesis by high LET radiation.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) 1994;14(10):355-61.
1994: Tom K Hei; J Bedford; Charles A Waldren
53 mutation hotspot in radon-associated lung cancer.
Lancet 1994;343(8906):1158-9.
1994: M L Shibuya; A M Ueno; Diane B Vannais; P A Craven; Charles A Waldren
Megabase pair deletions in mutant mammalian cells following exposure to amsacrine, an inhibitor of DNA topoisomerase II.
Cancer research 1994;54(4):1092-7.
1993: Theodore T Puck; H Morse; R Johnson; Charles A Waldren
Caffeine enhanced measurement of mutagenesis by low levels of gamma-irradiation in human lymphocytes.
Somatic cell and molecular genetics 1993;19(5):423-9.
1992: Tom K Hei; Chang Q Piao; Z Y He; Diane B Vannais; Charles A Waldren
Chrysotile fiber is a strong mutagen in mammalian cells.
Cancer research 1992;52(22):6305-9.
1992: Charles A Waldren; M Braaton; Diane B Vannais; B Fouladi; R D Parker
The use of human repetitive DNA to target selectable markers into only the human chromosome of a human-hamster hybrid cell line (AL)
Somatic cell and molecular genetics 1992;18(5):417-22.
1992: Jacqueline F Sinclair; B K Schaeffer; Sheryl G Wood; L K Lambrecht; Nadia Gorman; William J Bement; E L Smith; Peter R Sinclair; Charles A Waldren
2-Amino-3,4-dimethylimidazo[4,5-f]quinoline induces and inhibits cytochrome P450 from the IA subfamily in chick and rat hepatocytes.
Cancer research 1992;52(13):3615-21.
1991: Amato J Giaccia; A D Lewis; Nicholas C Denko; A Cholon; James W Evans; Charles A Waldren; Thomas D Stamato; J Martin Brown
The hypersensitivity of the Chinese hamster ovary variant BL-10 to bleomycin killing is due to a lack of glutathione S-transferase-alpha activity.
Cancer research 1991;51(16):4463-9.
1991: R L Anderson; K J Fong; T Gabriele; P Lavagnini; G M Hahn; James W Evans; Charles A Waldren; Thomas D Stamato; Amato J Giaccia
Loss of the intrinsic heat resistance of human cells and changes in Mr 70,000 heat shock protein expression in human x hamster hybrids.
Cancer research 1991;51(10):2636-41.
1991: N Matsukura; James Willey; M Miyashita; B Taffe; D Hoffmann; Charles A Waldren; T T Puck; C C Harris
Detection of direct mutagenicity of cigarette smoke condensate in mammalian cells.
Carcinogenesis 1991;12(4):685-9.
1991: E R Ritenour; M Braaton; George H Harrison; A Ueno; M Gadd; M Manco-Johnson; R Parker; S Shih; Charles A Waldren
Absence of mutagenic effects of continuous and pulsed ultrasound in cultured (AL) human-hamster hybrid cells.
Ultrasound in medicine & biology 1991;17(9):921-30.
1990: Amato J Giaccia; Nicholas C Denko; R MacLaren; D Mirman; Charles A Waldren; I Hart; Thomas D Stamato
Human chromosome 5 complements the DNA double-strand break-repair deficiency and gamma-ray sensitivity of the XR-1 hamster variant.
American journal of human genetics 1990;47(3):459-69.
1990: P Hentosh; Andrew Collins; L Correll; A J Fornace; Amato J Giaccia; Charles A Waldren
Genetic and biochemical characterization of the CHO-UV-1 mutant defective in postreplication recovery of DNA.
Cancer research 1990;50(8):2356-62.
1988: Tom K Hei; Eric J Hall; Charles A Waldren
Mutation induction and relative biological effectiveness of neutrons in mammalian cells. Experimental observations.
Radiation research 1988;115(2):281-91.
1988: R Parker; Charles A Waldren; Tom K Hei; D F Wong; T T Puck; T L Puck
Analysis of mutant frequency curves and survival curves applied to the AL hybrid cell system.
Journal of theoretical biology 1988;132(1):113-7.
1988: Andrew Collins; D T Black; Charles A Waldren
Aberrant DNA repair and enhanced mutagenesis following mutagen treatment of Chinese hamster Ade-C cells in a state of purine deprivation.
Mutation research 1988;193(2):145-55.
1987: Charles A Waldren; Theodore T Puck
Steps toward experimental measurement of total mutations relevant to human disease.
Somatic cell and molecular genetics 1987;13(4):411-4.
1987: Theodore T Puck; Charles A Waldren
Mutation in mammalian cells: theory and implications.
Somatic cell and molecular genetics 1987;13(4):405-9.
1986: Charles A Waldren; L Correll; M A Sognier; T T Puck
Measurement of low levels of x-ray mutagenesis in relation to human disease.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(13):4839-43.
1981: Thomas D Stamato; L Hinkle; Andrew Collins; Charles A Waldren
Chinese hamster ovary mutant UV-1 is hypomutable and defective in a postreplication recovery process.
Somatic cell genetics 1981;7(3):307-20.