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Grover Waldrop

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Chemicals & Drugs

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Escherichia coli

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Publications

TOP 3
Sherrisse K Bryant; Grover L Waldrop; S Douglass Gilman
A capillary electrophoretic assay for acetyl coenzyme A carboxylase.
Tyler C Broussard; Tyler S Champion; Matthew J Kobe; David B Neau; Svetlana Pakhomova; Amanda E Price; Grover L Waldrop
The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase.
Grover L Waldrop; Hazel M Holden; Martin St Maurice
The enzymes of biotin dependent CO₂ metabolism: what structures reveal about their reaction mechanisms.

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All Publications

2013: Sherrisse K Bryant; Grover L Waldrop; S Douglass Gilman
A capillary electrophoretic assay for acetyl coenzyme A carboxylase.
Analytical biochemistry 2013;437(1):32-8.
2013: Tyler C Broussard; Tyler S Champion; Matthew J Kobe; David B Neau; Svetlana Pakhomova; Amanda E Price; Grover L Waldrop
The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase.
Structure (London, England : 1993) 2013;21(4):650-7.
2012: Grover L Waldrop; Hazel M Holden; Martin St Maurice
The enzymes of biotin dependent CO₂ metabolism: what structures reveal about their reaction mechanisms.
Protein science : a publication of the Protein Society 2012;21(11):1597-619.
2011: G Meades; X Cai; N K Thalji; Grover L Waldrop; M de Queiroz
Mathematical modelling of negative feedback regulation by carboxyltransferase.
IET systems biology 2011;5(3):220-8.
2011: Brian R Novak; Dorel Moldovan; Grover L Waldrop; Marcio S de Queiroz
Behavior of the ATP grasp domain of biotin carboxylase monomers and dimers studied using molecular dynamics simulations.
Proteins 2011;79(2):622-32.
2010: Glen Meades; Rachel L Henken; Grover L Waldrop; Md Mukhlesur Rahman; S Douglass Gilman; Guy P P Kamatou; Alvaro M Viljoen; Simon Gibbons
Constituents of cinnamon inhibit bacterial acetyl CoA carboxylase.
Planta medica 2010;76(14):1570-5.
2010: Glen Meades; Brian K Benson; Anne Grove; Grover L Waldrop
A tale of two functions: enzymatic activity and translational repression by carboxyltransferase.
Nucleic acids research 2010;38(4):1217-27.
2010: J Richard Miller; Grover L Waldrop
Discovery of novel antibacterials.
Expert opinion on drug discovery 2010;5(2):145-54.
2009: Brian R Novak; Dorel Moldovan; Grover L Waldrop; Marcio S de Queiroz
Umbrella sampling simulations of biotin carboxylase: is a structure with an open ATP grasp domain stable in solution?
The journal of physical chemistry. B 2009;113(30):10097-103.
2009: Grover L Waldrop
Smaller is better for antibiotic discovery.
ACS chemical biology 2009;4(6):397-9.
2009: Tee Bordelon; Sten O Nilsson Lill; Grover L Waldrop
The utility of molecular dynamics simulations for understanding site-directed mutagenesis of glycine residues in biotin carboxylase.
Proteins 2009;74(4):808-19.
2009: Nabil K Thalji; William E Crowe; Grover L Waldrop
Kinetic mechanism and structural requirements of the amine-catalyzed decarboxylation of oxaloacetic acid.
The Journal of organic chemistry 2009;74(1):144-52.
2009: Grover L Waldrop
A qualitative approach to enzyme inhibition.
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 2009;37(1):11-5.
2008: Igor Mochalkin; Richard Miller; Artem Evdokimov; Sandra Lightle; Chunhong Yan; C Kendall Stover; Grover L Waldrop
Structural evidence for substrate-induced synergism and half-sites reactivity in biotin carboxylase.
Protein science : a publication of the Protein Society 2008;17(10):1706-18.
2008: Sten O Nilsson Lill; Jiali Gao; Grover L Waldrop
Molecular dynamics simulations of biotin carboxylase.
The journal of physical chemistry. B 2008;112(10):3149-56.
2008: Brian K Benson; Glen Meades; Anne Grove; Grover L Waldrop
DNA inhibits catalysis by the carboxyltransferase subunit of acetyl-CoA carboxylase: implications for active site communication.
Protein science : a publication of the Protein Society 2008;17(1):34-42.
2007: Marcio S de Queiroz; Grover L Waldrop
Modeling and numerical simulation of biotin carboxylase kinetics: implications for half-sites reactivity.
Journal of theoretical biology 2007;246(1):167-75.
2006: Qing-Gang Xue; Grover L Waldrop; Kevin L Schey; Naoki Itoh; Masahiro Ogawa; Richard K Cooper; Jack N Losso; Jerome F La Peyre
A novel slow-tight binding serine protease inhibitor from eastern oyster (Crassostrea virginica) plasma inhibits perkinsin, the major extracellular protease of the oyster protozoan parasite Perkinsus marinus.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2006;145(1):16-26.
2006: Nicholas Santoro; Teresa Brtva; Steve Vander Roest; Karen Siegel; Grover L Waldrop
A high-throughput screening assay for the carboxyltransferase subunit of acetyl-CoA carboxylase.
Analytical biochemistry 2006;354(1):70-7.
2006: Patrick Bilder; Sandra Lightle; Graeme Bainbridge; Jeffrey F Ohren; Barry Finzel; Fang Sun; Susan Holley; Loola Al-Kassim; Cindy Spessard; Michael Melnick; Marcia E Newcomer; Grover L Waldrop
The structure of the carboxyltransferase component of acetyl-coA carboxylase reveals a zinc-binding motif unique to the bacterial enzyme.
Biochemistry 2006;45(6):1712-22.
2004: Valerie Sloane; Grover L Waldrop
Kinetic characterization of mutations found in propionic acidemia and methylcrotonylglycinuria: evidence for cooperativity in biotin carboxylase.
The Journal of biological chemistry 2004;279(16):15772-8.
2002: John E Cronan; Grover L Waldrop
Multi-subunit acetyl-CoA carboxylases.
Progress in lipid research 2002;41(5):407-35.
2002: Keith L Levert; Grover L Waldrop; Jacqueline M Stephens
A biotin analog inhibits acetyl-CoA carboxylase activity and adipogenesis.
The Journal of biological chemistry 2002;277(19):16347-50.
2002: Keith L Levert; Grover L Waldrop
A bisubstrate analog inhibitor of the carboxyltransferase component of acetyl-CoA carboxylase.
Biochemical and biophysical research communications 2002;291(5):1213-7.
2001: K Janiyani; T Bordelon; Grover L Waldrop; John E Cronan
Function of Escherichia coli biotin carboxylase requires catalytic activity of both subunits of the homodimer.
The Journal of biological chemistry 2001;276(32):29864-70.
2001: V Sloane; CZ Blanchard; F Guillot; Grover L Waldrop
Site-directed mutagenesis of ATP binding residues of biotin carboxylase. Insight into the mechanism of catalysis.
The Journal of biological chemistry 2001;276(27):24991-6.
2000: James B Thoden; CZ Blanchard; Hazel M Holden; Grover L Waldrop
Movement of the biotin carboxylase B-domain as a result of ATP binding.
The Journal of biological chemistry 2000;275(21):16183-90.
2000: Keith L Levert; R B Lloyd; Grover L Waldrop
Do cysteine 230 and lysine 238 of biotin carboxylase play a role in the activation of biotin?
Biochemistry 2000;39(14):4122-8.
1999: CZ Blanchard; D Amspacher; Robert Strongin; Grover L Waldrop
Inhibition of biotin carboxylase by a reaction intermediate analog: implications for the kinetic mechanism.
Biochemical and biophysical research communications 1999;266(2):466-71.
1999: CZ Blanchard; Anne Chapman-Smith; John C Wallace; Grover L Waldrop
The biotin domain peptide from the biotin carboxyl carrier protein of Escherichia coli acetyl-CoA carboxylase causes a marked increase in the catalytic efficiency of biotin carboxylase and carboxyltransferase relative to free biotin.
The Journal of biological chemistry 1999;274(45):31767-9.
1999: D R Amspacher; CZ Blanchard; Frank R Fronczek; M C Saraiva; Grover L Waldrop; Robert Strongin
Synthesis of a reaction intermediate analogue of biotin-dependent carboxylases via a selective derivatization of biotin.
Organic letters 1999;1(1):99-102.
1999: CZ Blanchard; Y M Lee; P A Frantom; Grover L Waldrop
Mutations at four active site residues of biotin carboxylase abolish substrate-induced synergism by biotin.
Biochemistry 1999;38(11):3393-400.
1998: CZ Blanchard; Grover L Waldrop
Overexpression and kinetic characterization of the carboxyltransferase component of acetyl-CoA carboxylase.
The Journal of biological chemistry 1998;273(30):19140-5.