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Lore Brade

Research Profile

Chemicals & Drugs

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TOP 3
Cory L Brooks; Helmut Brade; Lore Brade; Paul Kosma; Sven Müller-Loennies; Kurt Wimmer; Stephen V Evans
Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide.
Kathryn Gomery; Paul Kosma; Sven Müller-Loennies; Helmut Brade; Lore Brade; Cory L Brooks; Franco Di Padova; Stephen V Evans
Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS.
Lore Brade; Franco Di Padova; Holger Heine; Gracjana Klein; Helmut Brade; Satish Raina; Sven Müller-Loennies
Immunization with an anti-idiotypic antibody against the broadly lipopolysaccharide-reactive antibody WN1 222-5 induces Escherichia coli R3-core-type specific antibodies in rabbits.

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All Publications

2013: Cory L Brooks; Helmut Brade; Lore Brade; Paul Kosma; Sven Müller-Loennies; Kurt Wimmer; Stephen V Evans
Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide.
Acta crystallographica. Section F, Structural biology and crystallization communications 2013;69(Pt 1):2-5.
2012: Kathryn Gomery; Paul Kosma; Sven Müller-Loennies; Helmut Brade; Lore Brade; Cory L Brooks; Franco Di Padova; Stephen V Evans
Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(51):20877-82.
2012: Lore Brade; Franco Di Padova; Holger Heine; Gracjana Klein; Helmut Brade; Satish Raina; Sven Müller-Loennies
Immunization with an anti-idiotypic antibody against the broadly lipopolysaccharide-reactive antibody WN1 222-5 induces Escherichia coli R3-core-type specific antibodies in rabbits.
Innate immunity 2012;18(2):279-93.
2011: Dylan W Evans; Helmut Brade; Lore Brade; Cory L Brooks; kosma paul; Sven Müller-Loennies; Stephen V Evans
Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia.
Glycobiology 2011;21(8):1049-59.
2011: Ryan J Blackler; Sven Müller-Loennies; Cory L Brooks; Dylan W Evans; Lore Brade; kosma paul; Helmut Brade; Stephen V Evans
A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.
Biochemistry 2011;50(16):3357-68.
2010: Cory Brooks; Ryan J Blackler; Georg Sixta; kosma paul; Sven Müller-Loennies; Lore Brade; Tomoko Hirama; C Roger MacKenzie; Helmut Brade; Stephen V Evans
The role of CDR H3 in antibody recognition of a synthetic analog of a lipopolysaccharide antigen.
Glycobiology 2010;20(2):138-47.
2010: Cory Brooks; Sven Müller-Loennies; Svetlana N Borisova; Lore Brade; kosma paul; Tomoko Hirama; C Roger MacKenzie; Helmut Brade; Stephen V Evans
Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition.
Biochemistry 2010;49(3):570-81.
2010: Sandra Gerstenbruch; Cory Brooks; kosma paul; Lore Brade; C Roger MacKenzie; Stephen V Evans; Helmut Brade; Sven Müller-Loennies
Analysis of cross-reactive and specific anti-carbohydrate antibodies against lipopolysaccharide from Chlamydophila psittaci.
Glycobiology 2010;20(4):461-72.
2010: Kai Schmengler; Torsten Goldmann; Lore Brade; Patricia M Sánchez Carballo; Sandra Albrecht; Helmut Brade; kosma paul; Hany Sahly; Hans-Peter Hauber; Florian Länger; Rudolf Meyer; Tobias Welte; Ulrich Zähringer
Monoclonal antibody S60-4-14 reveals diagnostic potential in the identification of Pseudomonas aeruginosa in lung tissues of cystic fibrosis patients.
European journal of cell biology 2010;89(1):25-33.
2008: Cory Brooks; Sven Müller-Loennies; Lore Brade; kosma paul; Tomoko Hirama; C Roger MacKenzie; Helmut Brade; Stephen V Evans
Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.
Journal of molecular biology 2008;377(2):450-68.
2008: Anna Hanuszkiewicz; Göran Hübner; Evgeny Vinogradov; Buko Lindner; Lore Brade; Helmut Brade; Jennifer Debarry; Holger Heine; Otto Holst
Structural and immunochemical analysis of the lipopolysaccharide from Acinetobacter lwoffii F78 located outside Chlamydiaceae with a Chlamydia-specific lipopolysaccharide epitope.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(33):10251-8.
2007: Sven Müller-Loennies; Lore Brade; Helmut Brade
Neutralizing and cross-reactive antibodies against enterobacterial lipopolysaccharide.
International journal of medical microbiology : IJMM 2007;297(5):321-40.
2006: Sven Müller-Loennies; Sabine Gronow; Lore Brade; Roger MacKenzie; kosma paul; Helmut Brade
A monoclonal antibody against a carbohydrate epitope in lipopolysaccharide differentiates Chlamydophila psittaci from Chlamydophila pecorum, Chlamydophila pneumoniae, and Chlamydia trachomatis.
Glycobiology 2006;16(3):184-96.
2005: Ulrich Seydel; Andra B Schromm; Lore Brade; Sabine Gronow; Jörg Andrä; Mareike Müller; Michel H J Koch; Koichi Fukase; Mikayo Kataoka; Masaya Hashimoto; Shoichi Kusumoto; Klaus Brandenburg
Physicochemical characterization of carboxymethyl lipid A derivatives in relation to biological activity.
The FEBS journal 2005;272(2):327-40.
2004: Rolf Göggel; Supandi Winoto-Morbach; Gabriele Vielhaber; Yumiko Imai; Karsten Lindner; Lore Brade; Helmut Brade; Stefan Ehlers; Arthur Slutsky; Stefan Schütze; Erich Gulbins; Stefan Uhlig
PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide.
Nature medicine 2004;10(2):155-60.
2003: Hoa P Nguyen; Nina O L Seto; C Roger MacKenzie; Lore Brade; kosma paul; Helmut Brade; Stephen V Evans
Germline antibody recognition of distinct carbohydrate epitopes.
Nature structural biology 2003;10(12):1019-25.
2003: Evgeny Vinogradov; Lore Brade; Helmut Brade; Otto Holst
Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter baumannii strain 24.
Carbohydrate research 2003;338(23):2751-6.
2003: Sven Muller-Loennies; Lore Brade; C Roger MacKenzie; Franco E Di Padova; Helmut Brade
Identification of a cross-reactive epitope widely present in lipopolysaccharide from enterobacteria and recognized by the cross-protective monoclonal antibody WN1 222-5.
The Journal of biological chemistry 2003;278(28):25618-27.
2003: Holger Heine; Sven Müller-Loennies; Lore Brade; Buko Lindner; Helmut Brade
Endotoxic activity and chemical structure of lipopolysaccharides from Chlamydia trachomatis serotypes E and L2 and Chlamydophila psittaci 6BC.
European journal of biochemistry / FEBS 2003;270(3):440-50.
2002: Lubomir Grozdanov; Ulrich Zähringer; Gabriele Blum-Oehler; Lore Brade; Anke Henne; Yuriy A Knirel; Ursula Schombel; Jürgen Schulze; Ulrich Sonnenborn; Gerhard Gottschalk; Jörg Hacker; Ernst Th Rietschel; Ulrich Dobrindt
A single nucleotide exchange in the wzy gene is responsible for the semirough O6 lipopolysaccharide phenotype and serum sensitivity of Escherichia coli strain Nissle 1917.
Journal of bacteriology 2002;184(21):5912-25.
2002: Sven Müller-Loennies; Lore Brade; Helmut Brade
Chemical structure and immunoreactivity of the lipopolysaccharide of the deep rough mutant I-69 Rd-/b+ of Haemophilus influenzae.
European journal of biochemistry / FEBS 2002;269(4):1237-42.
2002: Lore Brade; Sabine Gronow; Norbert Wimmer; kosma paul; Helmut Brade
Monoclonal antibodies against 3-deoxy-alpha-D-manno-oct-2-ulosonic acid (Kdo) and D-glycero-alpha-D-talo-oct-2-ulosonic acid (Ko).
Journal of endotoxin research 2002;8(5):357-64.
2002: Sven Müller-Loennies; Dieter Grimmecke; Lore Brade; Buko Lindner; kosma paul; Helmut Brade
A novel strategy for the synthesis of neoglycoconjugates from deacylated deep rough lipopolysaccharides.
Journal of endotoxin research 2002;8(4):295-305.
2002: Ralph Pantophlet; Juliëtte A Severin; Alexandr Nemec; Lore Brade; Lenie Dijkshoorn; Helmut Brade
Identification of Acinetobacter isolates from species belonging to the Acinetobacter calcoaceticus-Acinetobacter baumannii complex with monoclonal antibodies specific for O Antigens of their lipopolysaccharides.
Clinical and diagnostic laboratory immunology 2002;9(1):60-5.
2001: Hoa P Nguyen; Nina O L Seto; Lore Brade; kosma paul; Helmut Brade; Stephen V Evans
Crystallization and preliminary X-ray diffraction analysis of two homologous antigen-binding fragments in complex with different carbohydrate antigens.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 12):1872-6.
2001: Gabriele Vielhaber; S Pfeiffer; Lore Brade; Buko Lindner; Torsten Goldmann; E Vollmer; Ulrich Hintze; Klaus-Peter Wittern; Roger Wepf
Localization of ceramide and glucosylceramide in human epidermis by immunogold electron microscopy.
The Journal of investigative dermatology 2001;117(5):1126-36.
2001: Ralph Pantophlet; Alexandr Nemec; Lore Brade; Helmut Brade; Lenie Dijkshoorn
O-antigen diversity among Acinetobacter baumannii strains from the Czech Republic and Northwestern Europe, as determined by lipopolysaccharide-specific monoclonal antibodies.
Journal of clinical microbiology 2001;39(7):2576-80.
2001: Ralph Pantophlet; Lore Brade; Helmut Brade
Generation and serological characterization of murine monoclonal antibodies against O antigens from Acinetobacter reference strains.
Clinical and diagnostic laboratory immunology 2001;8(4):825-7.
2001: Gabriele Vielhaber; Lore Brade; Buko Lindner; S Pfeiffer; Roger Wepf; Ulrich Hintze; Klaus-Peter Wittern; Helmut Brade
Mouse anti-ceramide antiserum: a specific tool for the detection of endogenous ceramide.
Glycobiology 2001;11(6):451-7.
2001: A Reiter; Lore Brade; Patricia Sánchez Carballo; Helmut Brade; kosma paul
Synthesis and immunochemical characterization of neoglycoproteins containing epitopes of the inner core region of Pseudomonas aeruginosa RNA group I lipopolysaccharide.
Journal of endotoxin research 2001;7(2):125-31.
2001: Lore Brade; Rainer Podschun; Helmut Brade
A monoclonal antibody with specificity for the genus Klebsiella binds to a common epitope located in the core region of Klebsiella lipopolysaccharide.
Journal of endotoxin research 2001;7(2):119-24.
2001: Evelin Grage-Griebenow; Rainer Zawatzky; Helga Kahlert; Lore Brade; Hans-Dieter Flad; Martin Ernst
Identification of a novel dendritic cell-like subset of CD64(+) / CD16(+) blood monocytes.
European journal of immunology 2001;31(1):48-56.
2000: H Maaheimo; kosma paul; Lore Brade; H Brade; Thomas Peters
Mapping the binding of synthetic disaccharides representing epitopes of chlamydial lipopolysaccharide to antibodies with NMR.
Biochemistry 2000;39(42):12778-88.
2000: Lore Brade; Gabriele Vielhaber; E Heinz; Helmut Brade
In vitro characterization of anti-glucosylceramide rabbit antisera.
Glycobiology 2000;10(6):629-36.
2000: Ralph Pantophlet; Harald Seifert; Lore Brade; Helmut Brade
Antibody response to lipopolysaccharide in patients colonized or infected with an endemic strain of Acinetobacter genomic species 13 sensu Tjernberg and Ursing.
Clinical and diagnostic laboratory immunology 2000;7(2):293-5.
2000: Sven Müller-Loennies; C Roger MacKenzie; Sonia I Patenaude; Stephen V Evans; kosma paul; Helmut Brade; Lore Brade; Saran Narang
Characterization of high affinity monoclonal antibodies specific for chlamydial lipopolysaccharide.
Glycobiology 2000;10(2):121-30.
2000: Lore Brade
Assay of anti-endotoxin antibodies.
Methods in molecular medicine 2000;36():27-35.
2000: Lore Brade; Antoni Rozalski; kosma paul; Helmut Brade
A monoclonal antibody recognizing the 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) trisaccharide alphaKdo(2-->4)alphaKdo(2-->4)alphaKdo of Chlamydophila psittaci 6BC lipopolysaccharide.
Journal of endotoxin research 2000;6(5):361-8.
2000: kosma paul; A Reiter; Andreas Hofinger; Lore Brade; H Brade
Synthesis of neoglycoproteins containing Kdo epitopes specific for Chlamydophila psittaci lipopolysaccharide.
Journal of endotoxin research 2000;6(1):57-69.
2000: Lutz Hamann; Ralf R Schumann; Hans-Dieter Flad; Lore Brade; Ernst Th Rietschel; Artur J Ulmer
Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced NF-kappaB activation.
European journal of immunology 2000;30(1):211-6.
1999: Ralph Pantophlet; SR Haseley; Evgeny Vinogradov; Lore Brade; Otto Holst; Helmut Brade
Chemical and antigenic structure of the O-polysaccharide of the lipopolysaccharides from two Acinetobacter haemolyticus strains differing only in the anomeric configuration of one glycosyl residue in their O-antigens.
European journal of biochemistry / FEBS 1999;263(2):587-95.
1999: Ralph Pantophlet; Lore Brade; Helmut Brade
Use of a murine O-antigen-specific monoclonal antibody to identify Acinetobacter strains of unnamed genomic species 13 Sensu Tjernberg and Ursing.
Journal of clinical microbiology 1999;37(6):1693-8.
1999: T Haselhorst; J F Espinosa; J Jiménez-Barbero; T Sokolowski; kosma paul; H Brade; Lore Brade; Thomas Peters
NMR experiments reveal distinct antibody-bound conformations of a synthetic disaccharide representing a general structural element of bacterial lipopolysaccharide epitopes.
Biochemistry 1999;38(20):6449-59.
1999: Arnd Lentschat; Volker El-Samalouti; J Schletter; Shoichi Kusumoto; Lore Brade; Ernst Th Rietschel; J Gerdes; Martin Ernst; Hans-Dieter Flad; Artur J Ulmer
The internalization time course of a given lipopolysaccharide chemotype does not correspond to its activation kinetics in monocytes.
Infection and immunity 1999;67(5):2515-21.
1999: Ralph Pantophlet; Lore Brade; Helmut Brade
Identification of Acinetobacter baumannii strains with monoclonal antibodies against the O antigens of their lipopolysaccharides.
Clinical and diagnostic laboratory immunology 1999;6(3):323-9.
1999: Volker El-Samalouti; J Schletter; I Chyla; Arnd Lentschat; Uwe Mamat; Lore Brade; Hans-Dieter Flad; Artur J Ulmer; Lutz Hamann
Identification of the 80-kDa LPS-binding protein (LMP80) as decay-accelerating factor (DAF, CD55).
FEMS immunology and medical microbiology 1999;23(3):259-69.
1999: M Münstermann; Andre Wiese; Klaus Brandenburg; Ulrich Zähringer; Lore Brade; K Kawahara; Ulrich Seydel
Complement activation by bacterial surface glycolipids: a study with planar bilayer membranes.
The Journal of membrane biology 1999;167(3):223-32.
1998: T Sokolowski; T Haselhorst; K Scheffler; R Weisemann; kosma paul; H Brade; Lore Brade; Thomas Peters
Conformational analysis of a Chlamydia-specific disaccharide alpha-Kdo-(2-->8)-alpha-Kdo-(2-->O)-allyl in aqueous solution and bound to a monoclonal antibody: observation of intermolecular transfer NOEs.
Journal of biomolecular NMR 1998;12(1):123-33.
1998: Ralph Pantophlet; Lore Brade; Lenie Dijkshoorn; Helmut Brade
Specificity of rabbit antisera against lipopolysaccharide of Acinetobacter.
Journal of clinical microbiology 1998;36(5):1245-50.
1998: T Mattern; Hans-Dieter Flad; Lore Brade; Ernst Th Rietschel; Artur J Ulmer
Stimulation of human T lymphocytes by LPS is MHC unrestricted, but strongly dependent on B7 interactions.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3412-8.
1998: M Süsskind; Lore Brade; Helmut Brade; Otto Holst
Identification of a novel heptoglycan of alpha1-->2-linked D-glycero-D-manno-heptopyranose. Chemical and antigenic structure of lipopolysaccharides from Klebsiella pneumoniae ssp. pneumoniae rough strain R20 (O1-:K20-).
The Journal of biological chemistry 1998;273(12):7006-17.
1998: Otto Holst; M Süsskind; D Grimmecke; Lore Brade; Helmut Brade
Core structures of enterobacterial lipopolysaccharides.
Progress in clinical and biological research 1998;397():23-35.
1997: Volker El-Samalouti; J Schletter; Helmut Brade; Lore Brade; Shoichi Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Detection of lipopolysaccharide (LPS)-binding membrane proteins by immuno-coprecipitation with LPS and anti-LPS antibodies.
European journal of biochemistry / FEBS 1997;250(2):418-24.
1997: Lore Brade; Krystyna Zych; Antoni Rozalski; kosma paul; K Bock; Helmut Brade
Structural requirements of synthetic oligosaccharides to bind monoclonal antibodies against Chlamydia lipopolysaccharide.
Glycobiology 1997;7(6):819-27.
1997: Lore Brade; R Engel; W J Christ; Ernst Th Rietschel
A nonsubstituted primary hydroxyl group in position 6' of free lipid A is required for binding of lipid A monoclonal antibodies.
Infection and immunity 1997;65(9):3961-5.
1997: SR Haseley; Ralph Pantophlet; Lore Brade; Otto Holst; Helmut Brade
Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter junii strain 65.
European journal of biochemistry / FEBS 1997;245(2):477-81.
1997: Antoni Rozalski; Lore Brade; kosma paul; R Moxon; S Kusumoto; Helmut Brade
Characterization of monoclonal antibodies recognizing three distinct, phosphorylated carbohydrate epitopes in the lipopolysaccharide of the deep rough mutant I-69 Rd-/b+ of Haemophilus influenzae.
Molecular microbiology 1997;23(3):569-77.
1997: Evgeny Vinogradov; Ralph Pantophlet; SR Haseley; Lore Brade; Otto Holst; Helmut Brade
Structural and serological characterisation of the O-specific polysaccharide from lipopolysaccharide of Acinetobacter calcoaceticus strain 7 (DNA group 1).
European journal of biochemistry / FEBS 1997;243(1-2):167-73.
1996: Evgeny Vinogradov; Ralph Pantophlet; Lenie Dijkshoorn; Lore Brade; Otto Holst; Helmut Brade
Structural and serological characterisation of two O-specific polysaccharides of Acinetobacter.
European journal of biochemistry / FEBS 1996;239(3):602-10.
1996: Ernst Th Rietschel; Helmut Brade; Otto Holst; Lore Brade; Sven Müller-Loennies; Uwe Mamat; Ulrich Zähringer; F Beckmann; Ulrich Seydel; Klaus Brandenburg; Artur J Ulmer; T Mattern; Holger Heine; J Schletter; Harald Loppnow; Uwe Schönbeck; Hans-Dieter Flad; Sunna Hauschildt; U F Schade; F Di Padova; S Kusumoto; Ralf R Schumann
Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.
Current topics in microbiology and immunology 1996;216():39-81.
1995: J Schletter; Helmut Brade; Lore Brade; C Krüger; Harald Loppnow; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein.
Infection and immunity 1995;63(7):2576-80.
1995: Otto Holst; K Bock; Lore Brade; Helmut Brade
The structures of oligosaccharide bisphosphates isolated from the lipopolysaccharide of a recombinant Escherichia coli strain expressing the gene gseA [3-deoxy-D-manno-octulopyranosonic acid (Kdo) transferase] of Chlamydia psittaci 6BC.
European journal of biochemistry / FEBS 1995;229(1):194-200.
1994: M Lukácová; M Baumann; Lore Brade; Uwe Mamat; Helmut Brade
Lipopolysaccharide smooth-rough phase variation in bacteria of the genus Chlamydia.
Infection and immunity 1994;62(6):2270-6.
1994: Lore Brade; H Brunnemann; M Ernst; Y Fu; Otto Holst; kosma paul; H Näher; K Persson; Helmut Brade
Occurrence of antibodies against chlamydial lipopolysaccharide in human sera as measured by ELISA using an artificial glycoconjugate antigen.
FEMS immunology and medical microbiology 1994;8(1):27-41.
1993: H M Kuhn; Lore Brade; Ben J Appelmelk; S Kusumoto; Ernst Th Rietschel; Helmut Brade
The antibody reactivity of monoclonal lipid A antibodies is influenced by the acylation pattern of lipid A and the assay system employed.
Immunobiology 1993;189(5):457-71.
1993: Lore Brade; Otto Holst; Helmut Brade
An artificial glycoconjugate containing the bisphosphorylated glucosamine disaccharide backbone of lipid A binds lipid A monoclonal antibodies.
Infection and immunity 1993;61(10):4514-7.
1993: A Swierzko; Lore Brade; E C Höffgen; Helmut Brade
Specificity of rabbit antisera against the rough lipopolysaccharide of Salmonella minnesota strain R7 (chemotype Rd1P-).
FEMS immunology and medical microbiology 1993;7(3):265-70.
1993: A Swierzko; Lore Brade; H Paulsen; Helmut Brade
Specificity of rabbit antisera against the rough lipopolysaccharide of Salmonella minnesota R4 (chemotype Rd2P-)
Infection and immunity 1993;61(8):3216-21.
1993: Ernst Th Rietschel; Lore Brade; F U Schade; Ulrich Seydel; Ulrich Zähringer; Uwe Mamat; G Schmidt; Artur J Ulmer; Harald Loppnow; Hans-Dieter Flad
[Bacterial endotoxins: relationship between chemical structure and biological effect].
Immunität und Infektion 1993;21(2):26-35.
1992: H M Kuhn; Lore Brade; Helmut Brade
A complement-dependent enzyme immunoassay (C-EIA) with increased sensitivity for IgM-rich rabbit sera.
Journal of immunological methods 1992;155(2):201-6.
1992: M Baumann; Lore Brade; E Fasske; Helmut Brade
Staining of surface antigens of Chlamydia trachomatis L2 in tissue culture.
Infection and immunity 1992;60(10):4433-8.
1992: H M Kuhn; Lore Brade; Ben J Appelmelk; S Kusumoto; Ernst Th Rietschel; Helmut Brade
Characterization of the epitope specificity of murine monoclonal antibodies directed against lipid A.
Infection and immunity 1992;60(6):2201-10.
1992: Y Fu; M Baumann; kosma paul; Lore Brade; Helmut Brade
A synthetic glycoconjugate representing the genus-specific epitope of chlamydial lipopolysaccharide exhibits the same specificity as its natural counterpart.
Infection and immunity 1992;60(4):1314-21.
1991: Ernst Th Rietschel; Ulrich Seydel; Ulrich Zähringer; U F Schade; Lore Brade; Harald Loppnow; W Feist; M H Wang; Artur J Ulmer; Hans-Dieter Flad
Bacterial endotoxin: molecular relationships between structure and activity.
Infectious disease clinics of North America 1991;5(4):753-79.
1991: Otto Holst; Lore Brade; kosma paul; Helmut Brade
Structure, serological specificity, and synthesis of artificial glycoconjugates representing the genus-specific lipopolysaccharide epitope of Chlamydia spp.
Journal of bacteriology 1991;173(6):1862-6.
1990: G Schröder; Klaus Brandenburg; Lore Brade; Ulrich Seydel
Pore formation by complement in the outer membrane of gram-negative bacteria studied with asymmetric planar lipopolysaccharide/phospholipid bilayers.
The Journal of membrane biology 1990;118(2):161-70.
1990: Lore Brade; Otto Holst; kosma paul; Y X Zhang; H Paulsen; R Krausse; Helmut Brade
Characterization of murine monoclonal and murine, rabbit, and human polyclonal antibodies against chlamydial lipopolysaccharide.
Infection and immunity 1990;58(1):205-13.
1990: Ernst Th Rietschel; Lore Brade; U Schade; Ulrich Seydel; Ulrich Zähringer; Klaus Brandenburg; I Helander; Otto Holst; S Kondo; H M Kuhn
Bacterial lipopolysaccharides: relationship of structure and conformation to endotoxic activity, serological specificity and biological function.
Advances in experimental medicine and biology 1990;256():81-99.
1989: Antoni Rozalski; Lore Brade; H M Kuhn; Helmut Brade; kosma paul; Ben J Appelmelk; S Kusumoto; H Paulsen
Determination of the epitope specificity of monoclonal antibodies against the inner core region of bacterial lipopolysaccharides by use of 3-deoxy-D-manno-octulosonate-containing synthetic antigens.
Carbohydrate research 1989;193():257-70.
1989: Antoni Rozalski; Lore Brade; kosma paul; Ben J Appelmelk; C Krogmann; Helmut Brade
Epitope specificities of murine monoclonal and rabbit polyclonal antibodies against enterobacterial lipopolysaccharides of the Re chemotype.
Infection and immunity 1989;57(9):2645-52.
1988: Lore Brade; W G Bessler; Helmut Brade
Mitogenic activities of synthetic Escherichia coli lipid A and a synthetic partial structure (tripalmitoyl pentapeptide) of E. coli lipoprotein.
Infection and immunity 1988;56(5):1382-4.
1988: Helmut Brade; Lore Brade; Ernst Th Rietschel
Structure-activity relationships of bacterial lipopolysaccharides (endotoxins). Current and future aspects.
Zentralblatt für Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology 1988;268(2):151-79.
1988: Helmut Brade; Lore Brade; U Schade; Ulrich Zähringer; Otto Holst; H M Kuhn; Antoni Rozalski; E Röhrscheidt; Ernst Th Rietschel
Structure, endotoxicity, immunogenicity and antigenicity of bacterial lipopolysaccharides (endotoxins, O-antigens).
Progress in clinical and biological research 1988;272():17-45.
1987: Ernst Th Rietschel; Lore Brade; U Schade; C Galanos; Marina A Freudenberg; O Lüderitz; S Kusumoto; T Shiba
Endotoxic properties of synthetic pentaacyl lipid A precursor Ib and a structural isomer.
European journal of biochemistry / FEBS 1987;169(1):27-31.
1987: Lore Brade; Klaus Brandenburg; H M Kuhn; S Kusumoto; I Macher; Ernst Th Rietschel; Helmut Brade
The immunogenicity and antigenicity of lipid A are influenced by its physicochemical state and environment.
Infection and immunity 1987;55(11):2636-44.
1987: Ernst Th Rietschel; Lore Brade; Klaus Brandenburg; H D Flad; J de Jong-Leuveninck; K Kawahara; Buko Lindner; Harald Loppnow; T Lüderitz; U Schade
Chemical structure and biologic activity of bacterial and synthetic lipid A.
Reviews of infectious diseases 1987;9 Suppl 5():S527-36.
1987: H Brade; Lore Brade; F E Nano
Chemical and serological investigations on the genus-specific lipopolysaccharide epitope of Chlamydia.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(8):2508-12.
1987: Lore Brade; F E Nano; S Schlecht; S Schramek; H Brade
Antigenic and immunogenic properties of recombinants from Salmonella typhimurium and Salmonella minnesota rough mutants expressing in their lipopolysaccharide a genus-specific chlamydial epitope.
Infection and immunity 1987;55(2):482-6.
1987: Lore Brade; kosma paul; Ben J Appelmelk; H Paulsen; H Brade
Use of synthetic antigens to determine the epitope specificities of monoclonal antibodies against the 3-deoxy-D-manno-octulosonate region of bacterial lipopolysaccharide.
Infection and immunity 1987;55(2):462-6.
1987: Ernst Th Rietschel; Helmut Brade; Lore Brade; Klaus Brandenburg; U Schade; Ulrich Seydel; U Zähringer; C Galanos; O Lüderitz; O Westphal
Lipid A, the endotoxic center of bacterial lipopolysaccharides: relation of chemical structure to biological activity.
Progress in clinical and biological research 1987;231():25-53.
1986: Lore Brade; S Schramek; U Schade; H Brade
Chemical, biological, and immunochemical properties of the Chlamydia psittaci lipopolysaccharide.
Infection and immunity 1986;54(2):568-74.
1986: C Galanos; O Lüderitz; Marina A Freudenberg; Lore Brade; U Schade; Ernst Th Rietschel; S Kusumoto; T Shiba
Biological activity of synthetic heptaacyl lipid A representing a component of Salmonella minnesota R595 lipid A.
European journal of biochemistry / FEBS 1986;160(1):55-9.
1985: C Galanos; O Lüderitz; Ernst Th Rietschel; O Westphal; Helmut Brade; Lore Brade; Marina A Freudenberg; U Schade; M Imoto; H Yoshimura
Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities.
European journal of biochemistry / FEBS 1985;148(1):1-5.
1985: Ernst Th Rietschel; Helmut Brade; Lore Brade; W Kaca; K Kawahara; Buko Lindner; T Lüderitz; T Tomita; U Schade; Ulrich Seydel
Newer aspects of the chemical structure and biological activity of bacterial endotoxins.
Progress in clinical and biological research 1985;189():31-51.
1984: C Galanos; V Lehmann; O Lüderitz; Ernst Th Rietschel; O Westphal; Helmut Brade; Lore Brade; Marina A Freudenberg; T Hansen-Hagge; T Lüderitz
Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A.
European journal of biochemistry / FEBS 1984;140(2):221-7.