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Ameae Walker
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Research Profile (preview)
Chemicals & Drugs
Phenomena
Living Beings
Physiology
Anatomy
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Network (preview)
8
Kuo, Benson
8
Wu, Wei
7
Ueda, Eric Kinnosuke
7
Xu, Xiaolei
7
Coss, Djurdjica
5
Muller, Konrad
5
Yang, Lili
4
Owen-Schaub, Laurie
4
Tan, Dunyong
4
Bartolini, Paolo
4
Guzmán, Esther
3
Chen, Cyndi
3
Ho, Timothy
3
Huang, Kuang Tzu
3
Chen, Yen-Hao
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All Publications
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2009: Ueda Eric K M; Soares Carlos R J; Bartolini Paolo; DeGuzman Ariel; Lorenson Mary Y; Walker Ameae M
A molecular mimic of phosphorylated prolactin (S179D PRL) secreted by eukaryotic cells has a conformation with an increased positive surface charge compared to that of unmodified prolactin.
Biochemistry 2009;48(29):6887-97.
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2009: Helena Cleyde V; McKee De'Nise T; Bertram Richard; Walker Ameae M; Freeman Marc E
The rhythmic secretion of mating-induced prolactin secretion is controlled by prolactin acting centrally.
Endocrinology 2009;150(7):3245-51.
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2009: Deng Changhui; Ueda Eric; Chen Kuanhui E; Bula Craig; Norman Anthony W; Luben Richard A; Walker Ameae M
Prolactin blocks nuclear translocation of VDR by regulating its interaction with BRCA1 in osteosarcoma cells.
Molecular endocrinology (Baltimore, Md.) 2009;23(2):226-36.
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2008: Huang KuangTzu; Ueda Eric; Chen YenHao; Walker Ameae M
Paradigm-shifters: phosphorylated prolactin and short prolactin receptors.
Journal of mammary gland biology and neoplasia 2008;13(1):69-79.
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2008: Tan Dunyong; Huang Kuang Tzu; Ueda Eric; Walker Ameae M
S2 deletion variants of human PRL receptors demonstrate that extracellular domain conformation can alter conformation of the intracellular signaling domain.
Biochemistry 2008;47(1):479-89.
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2008: Guzmán Esther A; Langowski John L; De Guzman Ariel; Muller H Konrad; Walker Ameae M; Owen Laurie B
S179D prolactin diminishes the effects of UV light on epidermal gamma delta T cells.
Molecular and cellular endocrinology 2008;280(1-2):6-12.
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2008: Ma Lisa J; Walter Barbara; Deguzman Ariel; Muller H Konrad; Walker Ameae M
Trans-epithelial immune cell transfer during suckling modulates delayed-type hypersensitivity in recipients as a function of gender.
PloS one 2008;3(10):e3562.
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2007: Williams Valencia L; DeGuzman Ariel; Dang Hong; Kawaminami Mitsumori; Ho Timothy W C; Carter David G; Walker Ameae M
Common and specific effects of the two major forms of prolactin in the rat testis.
American journal of physiology. Endocrinology and metabolism 2007;293(6):E1795-803.
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2007: Wang Yanru; Chiu Christopher T; Nakamura Tamako; Walker Ameae M; Petridou Barbara; Trousdale Melvin D; Hamm-Alvarez Sarah F; Mircheff Austin K; Schechter Joel E
Traffic of endogenous, transduced, and endocytosed prolactin in rabbit lacrimal acinar cells.
Experimental eye research 2007;85(6):749-61.
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2007: Wu Wei; Zanello Laura; Walker Ameae M
S179D prolactin sensitizes human prostate cancer cells such that physiological concentrations of 1, 25 dihydroxy vitamin D3 result in growth inhibition and cell death.
The Prostate 2007;67(14):1498-506.
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2007: Walker Ameae M
S179D prolactin: antagonistic agony!
Molecular and cellular endocrinology 2007;276(1-2):1-9.
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2007: Ma Lisa J; Guzmán Esther A; DeGuzman Ariel; Muller H Konrad; Walker Ameae M; Owen Laurie B
Local cytokine levels associated with delayed-type hypersensitivity responses: modulation by gender, ovariectomy, and estrogen replacement.
The Journal of endocrinology 2007;193(2):291-7.
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2007: Wang Yanru; Chiu Christopher T; Nakamura Tamako; Walker Ameae M; Petridou Barbara; Trousdale Melvin D; Hamm-Alvarez Sarah F; Schechter Joel E; Mircheff Austin K
Elevated prolactin redirects secretory vesicle traffic in rabbit lacrimal acinar cells.
American journal of physiology. Endocrinology and metabolism 2007;292(4):E1122-34.
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2006: Walker Ameae M
Therapeutic potential of S179D prolactin--from prostate cancer to angioproliferative disorders: the first selective prolactin receptor modulator.
Expert opinion on investigational drugs 2006;15(10):1257-67.
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2006: Ueda Eric K; Lo Hsin-Lung; Bartolini Paolo; Walker Ameae M
S179D prolactin primarily uses the extrinsic pathway and mitogen-activated protein kinase signaling to induce apoptosis in human endothelial cells.
Endocrinology 2006;147(10):4627-37.
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2006: Ueda Eric; Ozerdem Ugur; Chen Yen-Hao; Yao Min; Huang Kuang Tzu; Sun Huiqin; Martins-Green Manuela; Bartolini Paolo; Walker Ameae M
A molecular mimic demonstrates that phosphorylated human prolactin is a potent anti-angiogenic hormone.
Endocrine-related cancer 2006;13(1):95-111.
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2006: Ma Lisa J; Guzmán Esther A; DeGuzman Ariel; Walter Barbara; Muller H Konrad; Walker Ameae M; Owen Laurie B
Unexpected effects of UVB in IL-10 transgenic mice: normalization of contact hypersensitivity response.
Archives of dermatological research 2006;297(9):417-20.
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2006: Langenheim John F; Tan Dunyong; Walker Ameae M; Chen Wen Y
Two wrongs can make a right: dimers of prolactin and growth hormone receptor antagonists behave as agonists.
Molecular endocrinology (Baltimore, Md.) 2006;20(3):661-74.
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2006: Wu Wei; Walker Ameae M
Human chorionic gonadotropin beta (HCGbeta) down-regulates E-cadherin and promotes human prostate carcinoma cell migration and invasion.
Cancer 2006;106(1):68-78.
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2006: Wu Wei; Chen Yen-Hao; Ueda Eric; Tan Dunyong; Bartolini Paolo; Walker Ameae M
Different forms of prolactin have opposing effects on the expression of cell cycle regulatory proteins in differentiated mammary epithelial cells.
Oncology research 2006;16(2):75-84.
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2005: Guzmán E A; Chen Y-H; Langowski J L; De Guzman A; Lo H-L; Walter B; Muller H K; Walker A M; Owen L B
Abrogation of delayed type hypersensitivity response to Candida albicans produced by a molecular mimic of phosphorylated prolactin.
Journal of neuroimmunology 2005;170(1-2):31-40.
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2005: Wu Wei; Ginsburg Erika; Vonderhaar Barbara K; Walker Ameae M
S179D prolactin increases vitamin D receptor and p21 through up-regulation of short 1b prolactin receptor in human prostate cancer cells.
Cancer research 2005;65(16):7509-15.
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2005: Naylor Matthew J; Oakes Samantha R; Gardiner-Garden Margaret; Harris Jessica; Blazek Katrina; Ho Timothy W C; Li Foo C; Wynick David; Walker Ameae M; Ormandy Christopher J
Transcriptional changes underlying the secretory activation phase of mammary gland development.
Molecular endocrinology (Baltimore, Md.) 2005;19(7):1868-83.
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2005: Tan Dunyong; Johnson David A; Wu Wei; Zeng Lingfang; Chen Yen Hao; Chen Wen Y; Vonderhaar Barbara K; Walker Ameae M
Unmodified prolactin (PRL) and S179D PRL-initiated bioluminescence resonance energy transfer between homo- and hetero-pairs of long and short human PRL receptors in living human cells.
Molecular endocrinology (Baltimore, Md.) 2005;19(5):1291-303.
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2005: Walker Ameae M
Prolactin receptor antagonists.
Current opinion in investigational drugs (London, England : 2000) 2005;6(4):378-85.
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2004: Huang Kuang Tzu; Chen Yen Hao; Walker Ameae M
Inaccuracies in MTS assays: major distorting effects of medium, serum albumin, and fatty acids.
BioTechniques 2004;37(3):406, 408, 410-2.
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2003: Schroeder Matthew D; Brockman Jennifer L; Walker Ameae M; Schuler Linda A
Inhibition of prolactin (PRL)-induced proliferative signals in breast cancer cells by a molecular mimic of phosphorylated PRL, S179D-PRL.
Endocrinology 2003;144(12):5300-7.
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2003: Wu Wei; Coss Djurdjica; Lorenson Mary Y; Kuo C Benson; Xu Xiaolei; Walker Ameae M
Different biological effects of unmodified prolactin and a molecular mimic of phosphorylated prolactin involve different signaling pathways.
Biochemistry 2003;42(24):7561-70.
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2003: Johnson Terence E; Vue Mayza; Brekhus Sharyn; Khong Amy; Ho Timothy W C; Walker Ameae M
Unmodified prolactin (PRL) promotes PRL secretion and acidophil hypertrophy and is associated with pituitary hyperplasia in female rats.
Endocrine 2003;20(1-2):101-10.
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2003: Xu Xiaolei; Wu Wei; Williams Valencia; Khong Amy; Chen Yen-Hao; Deng Changhui; Walker Ameae M
Opposite effects of unmodified prolactin and a molecular mimic of phosphorylated prolactin on morphology and the expression of prostate specific genes in the normal rat prostate.
The Prostate 2003;54(1):25-33.
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2002: Yang Lili; Lii Stella; Kuo Benson; Buckley Arthur; Buckley Donna; Chen Cyndi; Xu Xiaolei; Coss Djurdjica; Walker Ameae M
Maternal prolactin composition can permanently affect epidermal gammadeltaT cell function in the offspring.
Developmental and comparative immunology 2002;26(9):849-60.
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2002: Kuo C Benson; Wu Wei; Xu Xiaolei; Yang Lili; Chen Cyndi; Coss Djurdjica; Birdsall Ben; Nasseri Dorsa; Walker Ameae M
Pseudophosphorylated prolactin (S179D PRL) inhibits growth and promotes beta-casein gene expression in the rat mammary gland.
Cell and tissue research 2002;309(3):429-37.
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2002: Tuazon Polygena T; Lorenson Mary Y; Walker Ameae M; Traugh Jolinda A
p21-activated protein kinase gamma-PAK in pituitary secretory granules phosphorylates prolactin.
FEBS letters 2002;515(1-3):84-8.
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2001: Xu X; Kreye E; Kuo C B; Walker A M
A molecular mimic of phosphorylated prolactin markedly reduced tumor incidence and size when DU145 human prostate cancer cells were grown in nude mice.
Cancer research 2001;61(16):6098-104.
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2001: Yang L; Kuo C B; Liu Y; Coss D; Xu X; Chen C; Oster-Granite M L; Walker A M
Administration of unmodified prolactin (U-PRL) and a molecular mimic of phosphorylated prolactin (PP-PRL) during rat pregnancy provides evidence that the U-PRL:PP-PRL ratio is crucial to the normal development of pup tissues.
The Journal of endocrinology 2001;168(2):227-38.
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2001: Walker A M
Unmodified and phosphorylated prolactin and gamma delta T cell development and function.
Lupus 2001;10(10):735-41.
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2000: Coss D; Yang L; Kuo C B; Xu X; Luben R A; Walker A M
Effects of prolactin on osteoblast alkaline phosphatase and bone formation in the developing rat.
American journal of physiology. Endocrinology and metabolism 2000;279(6):E1216-25.
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1999: Coss D; Kuo C B; Yang L; Ingleton P; Luben R; Walker A M
Dissociation of Janus kinase 2 and signal transducer and activator of transcription 5 activation after treatment of Nb2 cells with a molecular mimic of phosphorylated prolactin.
Endocrinology 1999;140(11):5087-94.
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1998: Kuo C B; Coss D; Walker A M
Prolactin receptor antagonists.
Endocrine 1998;9(2):121-31.
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1998: Chen T J; Kuo C B; Tsai K F; Liu J W; Chen D Y; Walker A M
Development of recombinant human prolactin receptor antagonists by molecular mimicry of the phosphorylated hormone.
Endocrinology 1998;139(2):609-16.
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1997: Liu J W; Dawson D D; Peters C E; Baker M A; Walker A M
Estrogen replacement in ovariectomized rats results in physiologically significant levels of circulating progesterone, and co-administration of progesterone markedly reduces the circulating estrogen.
Endocrine 1997;6(2):125-31.
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1996: Lorenson M Y; Patel T; Liu J W; Walker A M
Prolactin (PRL) is a zinc-binding protein. I. Zinc interactions with monomeric PRL and divalent cation protection of intragranular PRL cysteine thiols.
Endocrinology 1996;137(3):809-16.
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1996: Wang Y F; Liu J W; Mamidi M; Walker A M
Identification of the major site of rat prolactin phosphorylation as serine 177.
The Journal of biological chemistry 1996;271(5):2462-9.
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1995: Walker A M; Montgomery D W; Saraiya S; Ho T W; Garewal H S; Wilson J; Lorand L
Prolactin-immunoglobulin G complexes from human serum act as costimulatory ligands causing proliferation of malignant B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3278-82.
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1994: Baker M A; Dawson D D; Peters C E; Walker A M
Effects of estrogen on thermoregulatory evaporation in rats exposed to heat.
The American journal of physiology 1994;267(3 Pt 2):R673-7.
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1994: Krown K A; Wang Y F; Walker A M
Autocrine interaction between prolactin and its receptor occurs intracellularly in the 235-1 mammotroph cell line.
Endocrinology 1994;134(3):1546-52.
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1993: Wang Y F; Walker A M
Dephosphorylation of standard prolactin produces a more biologically active molecule: evidence for antagonism between nonphosphorylated and phosphorylated prolactin in the stimulation of Nb2 cell proliferation.
Endocrinology 1993;133(5):2156-60.
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1993: Ho T W; Leong F S; Olaso C H; Walker A M
Secretion of specific nonphosphorylated and phosphorylated rat prolactin isoforms at different stages of the estrous cycle.
Neuroendocrinology 1993;58(2):160-5.
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1992: Langford C; Kadowaki J; Walker A M
In vitro glucoregulation of prolactin secretion.
Neuroendocrinology 1992;56(6):838-44.
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1992: Krown K A; Wang Y F; Ho T W; Kelly P A; Walker A M
Prolactin isoform 2 as an autocrine growth factor for GH3 cells.
Endocrinology 1992;131(2):595-602.
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1992: Wang Y F; Jia H; Walker A M; Cukierman S
K-current mediation of prolactin-induced proliferation of malignant (Nb2) lymphocytes.
Journal of cellular physiology 1992;152(1):185-9.
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1992: Walker A M; Peabody C A; Ho T W; Warner M D
50 kD prolactin binding protein in schizophrenics on neuroleptic medication.
Journal of psychiatry & neuroscience : JPN 1992;17(2):61-7.
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1991: Ho T W; Balden E; Chao J; Walker A M
Prolactin (PRL) processing by kallikrein: production of the 21-23.5K PRL-like molecules and inferences about PRL storage in mature secretory granules.
Endocrinology 1991;129(1):184-92.
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1991: Balden E; Walker A M; Cukierman S
Reconstitution of single calcium channels from secretory granules of rat adenohypophysis in planar lipid membranes.
Molecular and cellular endocrinology 1991;77(1-3):85-90.
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1990: Joe T L; Walker A M
Maternal dietary leucine supplementation affects apparent lactational activity and pup development in rats.
Journal of nutritional science and vitaminology 1990;36(6):609-18.
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1990: Greenan J; Lorenson M Y; Conconi M V; Walker A M
Alterations in in situ prolactin secretory granule morphology and immunoactivity by thiols and divalent cations.
Endocrinology 1990;126(1):512-8.
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1989: Greenan J R; Balden E; Ho T W; Walker A M
Biosynthesis of the secreted 24 K isoforms of prolactin.
Endocrinology 1989;125(4):2041-8.
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1989: Ho T W; Greenan J R; Walker A M
Mammotroph autoregulation: the differential roles of the 24K isoforms of prolactin.
Endocrinology 1989;124(3):1507-14.
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1989: Oetting W S; Ho T W; Greenan J R; Walker A M
Production and secretion of the 21-23.5 kDa prolactin-like molecules.
Molecular and cellular endocrinology 1989;61(2):189-99.
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