FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Cheryl Lyn Walker

Research Profile

Living Beings

Chemicals & Drugs

Disorders

Genes & Molecular Sequences

Genes, Tumor Suppressor

Physiology

Anatomy

Phenomena

Phosphorylation

Co-author Network

Publications

TOP 3
Cheryl Lyn Walker; Shuk-Mei Ho
Developmental reprogramming of cancer susceptibility.
Hiroaki Itamochi; Junzo Kigawa; Nao Suzuki; Naoki Terakawa; Daisuke Aoki; Chandra Bartholomeusz; Hideki Ishihara; Cheryl Lyn Walker; Tomokazu Yoshida; Naoto T Ueno
Novel mechanism of reduced proliferation in ovarian clear cell carcinoma cells: cytoplasmic sequestration of CDK2 by p27.
Cheryl Lyn Walker
Epigenomic reprogramming of the developing reproductive tract and disease susceptibility in adulthood.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Cheryl Lyn Walker (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Cheryl Lyn Walker; Shuk-Mei Ho
Developmental reprogramming of cancer susceptibility.
Nature reviews. Cancer 2012;12(7):479-86.
2011: Hiroaki Itamochi; Junzo Kigawa; Nao Suzuki; Naoki Terakawa; Daisuke Aoki; Chandra Bartholomeusz; Hideki Ishihara; Cheryl Lyn Walker; Tomokazu Yoshida; Naoto T Ueno
Novel mechanism of reduced proliferation in ovarian clear cell carcinoma cells: cytoplasmic sequestration of CDK2 by p27.
Gynecologic oncology 2011;122(3):641-7.
2011: Cheryl Lyn Walker
Epigenomic reprogramming of the developing reproductive tract and disease susceptibility in adulthood.
Birth defects research. Part A, Clinical and molecular teratology 2011;91(8):666-71.
2010: Angela Alexander; Cheryl Lyn Walker
Differential localization of ATM is correlated with activation of distinct downstream signaling pathways.
Cell cycle (Georgetown, Tex.) 2010;9(18):3685-6.
2010: Adrienne McCampbell; Russell R Broaddus; Cheryl Lyn Walker
Loss of inhibitory insulin receptor substrate-1 phosphorylation: An early event in endometrial hyperplasia and progression to carcinoma.
Cell cycle (Georgetown, Tex.) 2010;9(14):2698-9.
2010: Johnny D. Short; Ruhee Dere; Kevin D Houston; Sheng-Li Cai; Jinhee Kim; Judith M Bergeron; Jianjun Shen; Jiyong Liang; Mark T Bedford; Gordon B Mills; Cheryl Lyn Walker
AMPK-mediated phosphorylation of murine p27 at T197 promotes binding of 14-3-3 proteins and increases p27 stability.
Molecular carcinogenesis 2010;49(5):429-39.
2010: Angela Alexander; Sheng-Li Cai; Jinhee Kim; Adrian Nanez; Mustafa Sahin; Kirsteen H Maclean; Ken Inoki; Kun-Liang Guan; Jianjun Shen; Maria D Person; Donna F Kusewitt; Gordon B Mills; Michael B Kastan; Cheryl Lyn Walker
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4153-8.
2010: Ruhee Dere; Patricia D Wilson; Richard N Sandford; Cheryl Lyn Walker
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR.
PloS one 2010;5(2):e9239.
2009: Jorge Blando; Melisa Portis; Fernando Benavides; Angela Alexander; Gordon Mills; Bhuvanesh Dave; Claudio J Conti; Jeri Kim; Cheryl Lyn Walker
PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.
The American journal of pathology 2009;174(5):1869-79.
2009: Jane J Yu; Victoria A Robb; Tasha A Morrison; Eric A Ariazi; Magdalena Karbowniczek; Aristotelis Astrinidis; Chunrong Wang; Lisa Hernandez-Cuebas; Laura F Seeholzer; Emmanuelle Nicolas; Harvey H Hensley; V Craig Jordan; Cheryl Lyn Walker; Elizabeth Petri Henske
Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2635-40.
2009: Jinhee Kim; Eric Jonasch; Angela Alexander; Johnny D. Short; Shengli Cai; Sijin Wen; Dimitra Tsavachidou; Pheroze Tamboli; Bogdan A Czerniak; Kim-Anh Do; Kevin J Wu; Laura A Marlow; Christopher G Wood; John A Copland; Cheryl Lyn Walker
Cytoplasmic sequestration of p27 via AKT phosphorylation in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(1):81-90.
2008: Adrienne McCampbell; Cheryl Lyn Walker; Russell R Broaddus; Jennifer D Cook; Peter Davies
Developmental reprogramming of IGF signaling and susceptibility to endometrial hyperplasia in the rat.
Laboratory investigation; a journal of technical methods and pathology 2008;88(6):615-26.
2008: Karen H Lu; Weiguo Wu; Bhuvanesh Dave; Brian M Slomovitz; Thomas W Burke; Mark F Munsell; Russell R Broaddus; Cheryl Lyn Walker
Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(9):2543-50.
2008: Chongjuan Wei; Christopher I Amos; Nianxiang Zhang; Xiaopei Wang; Asif Rashid; Cheryl Lyn Walker; Richard R Behringer; Marsha L Frazier
Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1167-71.
2008: Teresa K Woodruff; Cheryl Lyn Walker
Fetal and early postnatal environmental exposures and reproductive health effects in the female.
Fertility and sterility 2008;89(2 Suppl):e47-51.
2008: Aki Isobe; Takashi Takeda; Masahiro Sakata; Asako Miyake; Toshiya Yamamoto; Ryoko Minekawa; Fumihito Nishimoto; Yoko Oskamoto; Cheryl Lyn Walker; Tadashi Kimura
Dual repressive effect of angiotensin II-type 1 receptor blocker telmisartan on angiotensin II-induced and estradiol-induced uterine leiomyoma cell proliferation.
Human reproduction (Oxford, England) 2008;23(2):440-6.
2007: Nicholas J Laping; Jeffrey I Everitt; Kendall S Frazier; Mark Burgert; Melisa J Portis; Caprice Cadacio; Leslie I Gold; Cheryl Lyn Walker
Tumor-specific efficacy of transforming growth factor-beta RI inhibition in Eker rats.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(10):3087-99.
2007: Jennifer DeAnn Cook; Barbara J Davis; Julia Alicia Goewey; Tia D Berry; Cheryl Lyn Walker
Identification of a sensitive period for developmental programming that increases risk for uterine leiomyoma in Eker rats.
Reproductive sciences (Thousand Oaks, Calif.) 2007;14(2):121-36.
2007: William Hall; Bruce Elder; Cheryl Lyn Walker; Sheng-Li Cai; David G Peters; DAWN GOODMAN; Borge M Ulland; Joseph F Borzelleca
Spontaneous renal tubular hyperplastic and neoplastic lesions in three Sprague-Dawley rats from a 90-day toxicity study.
Toxicologic pathology 2007;35(2):233-41.
2007: Jiyong Liang; Shan H Shao; Zhi-Xiang Xu; Bryan T. J. Hennessy; Zhiyong Ding; Michelle Larrea; Seiji Kondo; Dan J Dumont; Jordan U Gutterman; Cheryl Lyn Walker; Joyce M Slingerland; Gordon B Mills
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis.
Nature cell biology 2007;9(2):218-24.
2006: Angela Mally; Cheryl Lyn Walker; Jeffrey I Everitt; Wolfgang Dekant; Spyros Vamvakas
Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro.
Toxicology 2006;224(1-2):108-18.
2006: Sheng-Li Cai; Andrew R Tee; Johnny D. Short; Judith M Bergeron; Jinhee Kim; Jianjun Shen; Ruifeng Guo; Charles L Johnson; Kaoru Kiguchi; Cheryl Lyn Walker
Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning.
The Journal of cell biology 2006;173(2):279-89.
2006: Sheng-Li Cai; Cheryl Lyn Walker
TSC2, a key player in tumor suppression and cystic kidney disease.
Néphrologie & thérapeutique 2006;2 Suppl 2():S119-22.
2005: Jennifer D Cook; Barbara J Davis; Sheng-Li Cai; J Carl Barrett; Claudio J Conti; Cheryl Lyn Walker
Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(24):8644-9.
2005: Cheryl Lyn Walker; Elizabeth A Stewart
Uterine fibroids: the elephant in the room.
Science (New York, N.Y.) 2005;308(5728):1589-92.
2004: Jennifer D Cook; Cheryl Lyn Walker
Treatment strategies for uterine leiomyoma: the role of hormonal modulation.
Seminars in reproductive medicine 2004;22(2):105-11.
2004: Elena Kleymenova; Jeffrey I Everitt; Linda Pluta; Melisa Portis; James R Gnarra; Cheryl Lyn Walker
Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice.
Carcinogenesis 2004;25(3):309-15.
2003: Cheryl Lyn Walker; Deborah Hunter; Jeffery I Everitt
Uterine leiomyoma in the Eker rat: a unique model for important diseases of women.
Genes, chromosomes & cancer 2003;38(4):349-56.
2003: Thomas W Burke; Cheryl Lyn Walker
Arzoxifene as therapy for endometrial cancer.
Gynecologic oncology 2003;90(2 Pt 2):S40-6.
2003: Geraldine A Finlay; Deborah S Hunter; Cheryl Lyn Walker; K E Paulson; Barry L Fanburg
Regulation of PDGF production and ERK activation by estrogen is associated with TSC2 gene expression.
American journal of physiology. Cell physiology 2003;285(2):C409-18.
2003: Kevin D Houston; John A Copland; Russell R Broaddus; Marco Gottardis; Susan M Fischer; Cheryl Lyn Walker
Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma.
Cancer research 2003;63(6):1221-7.
2003: Leslie C Hodges; Jennifer D Cook; Edward K Lobenhofer; Leping Li; Lee Bennett; Pierre R Bushel; C Marcelo Aldaz; Cynthia A Afshari; Cheryl Lyn Walker
Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast cancer cells.
Molecular cancer research : MCR 2003;1(4):300-11.
2003: Shengli Cai; Jeffrey I Everitt; Hiroyuki Kugo; Jennifer Cook; Elena Kleymenova; Cheryl Lyn Walker
Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development.
The American journal of pathology 2003;162(2):457-68.
2003: Kimberley Cesen-Cummings; Kevin D Houston; John A Copland; Valerie J Moorman; Cheryl Lyn Walker; Barbara J Davis
Uterine leiomyomas express myometrial contractile-associated proteins involved in pregnancy-related hormone signaling.
Journal of the Society for Gynecologic Investigation 2003;10(1):11-20.
2002: Aristotelis Astrinidis; Timothy P Cash; Deborah S Hunter; Cheryl Lyn Walker; Jonathan Chernoff; Elizabeth Petri Henske
Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration.
Oncogene 2002;21(55):8470-6.
2002: Matt Y Liu; Shengli Cai; Alexsandra Espejo; Mark T Bedford; Cheryl Lyn Walker
14-3-3 interacts with the tumor suppressor tuberin at Akt phosphorylation site(s).
Cancer research 2002;62(22):6475-80.
2002: Leslie C Hodges; Kevin D Houston; Deborah S Hunter; Robin Fuchs-Young; Zhiming Zhang; Richard C Wineker; Cheryl Lyn Walker
Transdominant suppression of estrogen receptor signaling by progesterone receptor ligands in uterine leiomyoma cells.
Molecular and cellular endocrinology 2002;196(1-2):11-20.
2002: Elena A Goncharova; Dmitry A Goncharov; Andrew Eszterhas; Deborah S Hunter; Marilyn Glassberg Csete; Raymond S Yeung; Cheryl Lyn Walker; Daniel Noonan; David J Kwiatkowski; Margaret M Chou; Reynold A Panettieri; Vera P Krymskaya
Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM).
The Journal of biological chemistry 2002;277(34):30958-67.
2002: Hae-Seong Yoon; Terrence J Monks; Jeffrey I Everitt; Cheryl Lyn Walker; Serrine S Lau
Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity.
American journal of physiology. Renal physiology 2002;283(2):F262-70.
2002: Deborah S Hunter; Michael Klotzbücher; Hiroyuki Kugoh; Sheng-Li Cai; Johanna Mullen; Guidalberto Manfioletti; Ulrike Fuhrman; Cheryl Lyn Walker
Aberrant expression of HMGA2 in uterine leiomyoma associated with loss of TSC2 tumor suppressor gene function.
Cancer research 2002;62(13):3766-72.
2002: Carla Irani; Elena A Goncharova; Deborah S Hunter; Cheryl Lyn Walker; Reynold A Panettieri; Vera P Krymskaya
Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration.
American journal of physiology. Lung cellular and molecular physiology 2002;282(4):L854-62.
2002: Hiroyuki Kugoh; Elena Kleymenova; Cheryl Lyn Walker
Retention of membrane-localized beta-catenin in cells lacking functional polycystin-1 and tuberin.
Molecular carcinogenesis 2002;33(3):131-6.
2002: Cheryl Lyn Walker
Role of hormonal and reproductive factors in the etiology and treatment of uterine leiomyoma.
Recent progress in hormone research 2002;57():277-94.
2002: KD Burroughs; S R Howe; Y Okubo; Robin Fuchs-Young; Derek LeRoith; Cheryl Lyn Walker
Dysregulation of IGF-I signaling in uterine leiomyoma.
The Journal of endocrinology 2002;172(1):83-93.
2001: H Xu; J Shen; Cheryl Lyn Walker; Elena Kleymenova
Tissue-specific expression and splicing of the rat polycystic kidney disease 1 gene.
DNA sequence : the journal of DNA sequencing and mapping 2001;12(5-6):361-6.
2001: Leslie C Hodges; Deborah S Hunter; JS Bergerson; Robin Fuchs-Young; Cheryl Lyn Walker
An in vivo/in vitro model to assess endocrine disrupting activity of xenoestrogens in uterine leiomyoma.
Annals of the New York Academy of Sciences 2001;948():100-11.
2001: Cheryl Lyn Walker; Kimberley Cesen-Cummings; C Houle; D Baird; J Carl Barrett; B Davis
Protective effect of pregnancy for development of uterine leiomyoma.
Carcinogenesis 2001;22(12):2049-52.
2001: Hae-Seong Yoon; Terrence J Monks; Cheryl Lyn Walker; Serrine S Lau
Transformation of kidney epithelial cells by a quinol thioether via inactivation of the tuberous sclerosis-2 tumor suppressor gene.
Molecular carcinogenesis 2001;31(1):37-45.
2001: Elena Kleymenova; Cheryl Lyn Walker
Determination of loss of heterozygosity in frozen and paraffin embedded tumors by denaturating high-performance liquid chromatography (DHPLC).
Journal of biochemical and biophysical methods 2001;47(1-2):83-90.
2001: Serrine S Lau; Hae-Seong Yoon; Sonal K Patel; Jeffrey I Everitt; Cheryl Lyn Walker; Terrence J Monks
Mutagenicity and carcinogenicity of biological reactive intermediate's derived from a "non-genotoxic" carcinogen.
Advances in experimental medicine and biology 2001;500():83-92.
2001: Kevin D Houston; Deborah S Hunter; Leslie C Hodges; Cheryl Lyn Walker
Uterine leiomyomas: mechanisms of tumorigenesis.
Toxicologic pathology 2001;29(1):100-4.
2001: Serrine S Lau; Terrence J Monks; Jeffrey I Everitt; Elena Kleymenova; Cheryl Lyn Walker
Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone.
Chemical research in toxicology 2001;14(1):25-33.
2000: Kimberley Cesen-Cummings; Cheryl Lyn Walker; Barbara J Davis
Lessons from pregnancy and parturition: uterine leiomyomas result from discordant differentiation and dedifferentiation responses in smooth muscle cells.
Medical hypotheses 2000;55(6):485-90.
2000: KD Burroughs; Robin Fuchs-Young; B Davis; Cheryl Lyn Walker
Altered hormonal responsiveness of proliferation and apoptosis during myometrial maturation and the development of uterine leiomyomas in the rat.
Biology of reproduction 2000;63(5):1322-30.
2000: Elena Kleymenova; Stephanie J. Muga; S Fischer; Cheryl Lyn Walker
Application of high-performance liquid chromatography-based analysis of DNA fragments to molecular carcinogenesis.
Molecular carcinogenesis 2000;29(2):51-8.
2000: Deborah S Hunter; Leslie C Hodges; P K Eagon; P M Vonier; Robin Fuchs-Young; JS Bergerson; Cheryl Lyn Walker
Influence of exogenous estrogen receptor ligands on uterine leiomyoma: evidence from an in vitro/in vivo animal model for uterine fibroids.
Environmental health perspectives 2000;108 Suppl 5():829-34.
2000: Kimberley Cesen-Cummings; John A Copland; J Carl Barrett; Cheryl Lyn Walker; Barbara J Davis
Pregnancy, parturition, and prostaglandins: defining uterine leiomyomas.
Environmental health perspectives 2000;108 Suppl 5():817-20.
2000: Cheryl Lyn Walker; KD Burroughs; B Davis; K Sowell; J I Everitt; Robin Fuchs-Young
Preclinical evidence for therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma.
Journal of the Society for Gynecologic Investigation 2000;7(4):249-56.
2000: A D Perera; Elena Kleymenova; Cheryl Lyn Walker
Requirement for the von Hippel-Lindau tumor suppressor gene for functional epidermal growth factor receptor blockade by monoclonal antibody C225 in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1518-23.
2000: Leslie C Hodges; JS Bergerson; Deborah S Hunter; Cheryl Lyn Walker
Estrogenic effects of organochlorine pesticides on uterine leiomyoma cells in vitro.
Toxicological sciences : an official journal of the Society of Toxicology 2000;54(2):355-64.
1999: Elena Kleymenova; J E Declue; Cheryl Lyn Walker
Genetic variants of the tuberous sclerosis 2 tumour suppressor gene in mouse t haplotypes.
Genetical research 1999;74(2):139-44.
1999: Deborah S Hunter; Leslie C Hodges; P M Vonier; Robin Fuchs-Young; Marco Gottardis; Cheryl Lyn Walker
Estrogen receptor activation via activation function 2 predicts agonism of xenoestrogens in normal and neoplastic cells of the uterine myometrium.
Cancer research 1999;59(13):3090-9.
1999: Jamie Andrew Davies; A D Perera; Cheryl Lyn Walker
Mechanisms of epithelial development and neoplasia in the metanephric kidney.
The International journal of developmental biology 1999;43(5):473-8.
1998: Gabriela Rennebeck; Elena Kleymenova; R Anderson; Raymond S Yeung; Karen Artzt; Cheryl Lyn Walker
Loss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15629-34.
1998: Elena Kleymenova; X Yuan; M E LaBate; Cheryl Lyn Walker
Identification of a tumor-specific methylation site in the Wilms tumor suppressor gene.
Oncogene 1998;16(6):713-20.
1997: J I Everitt; Cheryl Lyn Walker; T W Goldsworthy; Douglas Wolf
Altered expression of transforming growth factor-alpha: an early event in renal cell carcinoma development.
Molecular carcinogenesis 1997;19(3):213-9.
1997: Elena Kleymenova; A A Bianchi; N Kley; L N Pylev; Cheryl Lyn Walker
Characterization of the rat neurofibromatosis 2 gene and its involvement in asbestos-induced mesothelioma.
Molecular carcinogenesis 1997;18(1):54-60.
1995: Jeffrey I Everitt; T L Goldsworthy; Douglas Wolf; Cheryl Lyn Walker
Hereditary renal cell carcinoma in the Eker rat: a unique animal model for the study of cancer susceptibility.
Toxicology letters 1995;82-83():621-5.
1995: Raymond S Yeung; Guang-Hui Xiao; Jeffrey I Everitt; F Jin; Cheryl Lyn Walker
Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat.
Molecular carcinogenesis 1995;14(1):28-36.
1995: A A Rutten; Edilberto Bermudez; W Stewart; Jeffrey I Everitt; Cheryl Lyn Walker
Expression of insulin-like growth factor II in spontaneously immortalized rat mesothelial and spontaneous mesothelioma cells: a potential autocrine role of insulin-like growth factor II.
Cancer research 1995;55(16):3634-9.
1994: Edilberto Bermudez; Z Chen; Elizabeth A Gross; Cheryl Lyn Walker; Leslie Recio; Linda Pluta; Kevin T Morgan
Characterization of cell lines derived from formaldehyde-induced nasal tumors in rats.
Molecular carcinogenesis 1994;9(4):193-9.
1992: Jeffrey I Everitt; Thomas L Goldsworthy; Douglas Wolf; Cheryl Lyn Walker
Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome.
The Journal of urology 1992;148(6):1932-6.