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John Walker

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Disorders

Neuroblastoma

Anatomy

Concepts & Ideas

Molecular Sequence Data

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Co-Publications
Name
18
Ponnambalam, Sreenivasan
17
Vaughan, Peter
11
Trotter, Patrick
10
Orchard, MA
6
Murphy, Jane
6
Tzima, E
6
Ball, Stephen
6
Herbert, Shane
6
Homer-Vanniasinkam, Shervanthi
5
Danks, K
5
Vohra, Ravinder
4
Howell, Gareth
4
Zachary, Ian
3
Grewal, Seema
2
Gawler, Debra

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Publications

TOP 3
Bruns Alexander F; Bao Leyuan; Walker John H; Ponnambalam Sreenivasan
VEGF-A-stimulated signalling in endothelial cells via a dual receptor tyrosine kinase system is dependent on co-ordinated trafficking and proteolysis.
Jopling Helen M; Odell Adam F; Hooper Nigel M; Zachary Ian C; Walker John H; Ponnambalam Sreenivasan
Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells.
Vohra Ravinder S; Walker John H; Howell Gareth J; Homer-Vanniasinkam Shervanthi; Ponnambalam Sreenivasan
The LOX-1 scavenger receptor cytoplasmic domain contains a transplantable endocytic motif.

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All Publications

2009: Bruns Alexander F; Bao Leyuan; Walker John H; Ponnambalam Sreenivasan
VEGF-A-stimulated signalling in endothelial cells via a dual receptor tyrosine kinase system is dependent on co-ordinated trafficking and proteolysis.
Biochemical Society transactions 2009;37(Pt 6):1193-7.
2009: Jopling Helen M; Odell Adam F; Hooper Nigel M; Zachary Ian C; Walker John H; Ponnambalam Sreenivasan
Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(7):1119-24.
2009: Vohra Ravinder S; Walker John H; Howell Gareth J; Homer-Vanniasinkam Shervanthi; Ponnambalam Sreenivasan
The LOX-1 scavenger receptor cytoplasmic domain contains a transplantable endocytic motif.
Biochemical and biophysical research communications 2009;383(2):269-74.
2009: Mittar Shweta; Ulyatt Clare; Howell Gareth J; Bruns Alexander F; Zachary Ian; Walker John H; Ponnambalam Sreenivasan
VEGFR1 receptor tyrosine kinase localization to the Golgi apparatus is calcium-dependent.
Experimental cell research 2009;315(5):877-89.
2009: Herbert Shane P; Odell Adam F; Ponnambalam Sreenivasan; Walker John H
Activation of cytosolic phospholipase A2-{alpha} as a novel mechanism regulating endothelial cell cycle progression and angiogenesis.
The Journal of biological chemistry 2009;284(9):5784-96.
2008: Locate Salma; Colyer John; Gawler Debra J; Walker John H
Annexin A6 at the cardiac myocyte sarcolemma--evidence for self-association and binding to actin.
Cell biology international 2008;32(11):1388-96.
2008: Murphy Jane E; Vohra Ravinder S; Dunn Sarah; Holloway Zoe G; Monaco Anthony P; Homer-Vanniasinkam Shervanthi; Walker John H; Ponnambalam Sreenivasan
Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2.
Journal of cell science 2008;121(Pt 13):2136-47.
2008: Dunn Sarah; Vohra Ravinder S; Murphy Jane E; Homer-Vanniasinkam Shervanthi; Walker John H; Ponnambalam Sreenivasan
The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease.
The Biochemical journal 2008;409(2):349-55.
2007: Herbert Shane P; Odell Adam F; Ponnambalam Sreenivasan; Walker John H
The confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation.
The Journal of biological chemistry 2007;282(47):34468-78.
2007: Vohra Ravinder S; Murphy Jane E; Walker John H; Homer-Vanniasinkam Shervanthi; Ponnambalam Sreenivasan
Functional refolding of a recombinant C-type lectin-like domain containing intramolecular disulfide bonds.
Protein expression and purification 2007;52(2):415-21.
2006: Herbert Shane P; Walker John H
Group VIA calcium-independent phospholipase A2 mediates endothelial cell S phase progression.
The Journal of biological chemistry 2006;281(47):35709-16.
2006: Ewan Lorna C; Jopling Helen M; Jia Haiyan; Mittar Shweta; Bagherzadeh Azadeh; Howell Gareth J; Walker John H; Zachary Ian C; Ponnambalam Sreenivasan
Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells.
Traffic (Copenhagen, Denmark) 2006;7(9):1270-82.
2006: Vohra Ravinder S; Murphy Jane E; Walker John H; Ponnambalam Sreenivasan; Homer-Vanniasinkam Shervanthi
Atherosclerosis and the Lectin-like OXidized low-density lipoprotein scavenger receptor.
Trends in cardiovascular medicine 2006;16(2):60-4.
2006: Murphy Jane E; Tacon Daryl; Tedbury Philip R; Hadden Jonathan M; Knowling Stuart; Sawamura Tatsuya; Peckham Michelle; Phillips Simon E V; Walker John H; Ponnambalam Sreenivasan
LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells.
The Biochemical journal 2006;393(Pt 1):107-15.
2005: Murphy Jane E; Tedbury Philip R; Homer-Vanniasinkam Shervanthi; Walker John H; Ponnambalam Sreenivasan
Biochemistry and cell biology of mammalian scavenger receptors.
Atherosclerosis 2005;182(1):1-15.
2005: Herbert S P; Ponnambalam S; Walker J H
Cytosolic phospholipase A2-alpha mediates endothelial cell proliferation and is inactivated by association with the Golgi apparatus.
Molecular biology of the cell 2005;16(8):3800-9.
2005: Grewal Seema; Herbert Shane P; Ponnambalam Sreenivasan; Walker John H
Cytosolic phospholipase A2-alpha and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus.
The FEBS journal 2005;272(5):1278-90.
2005: Gedge L J E; Morrison E E; Blair G E; Walker J H
Nuclear actin is partially associated with Cajal bodies in human cells in culture and relocates to the nuclear periphery after infection of cells by adenovirus 5.
Experimental cell research 2005;303(2):229-39.
2004: Howell Gareth J; Herbert Shane P; Smith Jennifer M; Mittar Shweta; Ewan Lorna C; Mohammed Mudassir; Hunter Alison R; Simpson Nigel; Turner Anthony J; Zachary Ian; Walker John H; Ponnambalam Sreenivasan
Endothelial cell confluence regulates Weibel-Palade body formation.
Molecular membrane biology 2004;21(6):413-21.
2003: Grewal Seema; Ponnambalam Sreenivasan; Walker John H
Association of cPLA2-alpha and COX-1 with the Golgi apparatus of A549 human lung epithelial cells.
Journal of cell science 2003;116(Pt 11):2303-10.
2002: Grewal Seema; Morrison Ewan E; Ponnambalam Sreenivasan; Walker John H
Nuclear localisation of cytosolic phospholipase A2-alpha in the EA.hy.926 human endothelial cell line is proliferation dependent and modulated by phosphorylation.
Journal of cell science 2002;115(Pt 23):4533-43.
2001: Hartness M E; Wade J A; Walker J H; Vaughan P F
Overexpression of the myristoylated alanine-rich C kinase substrate decreases uptake and K(+)-evoked release of noradrenaline in the human neuroblastoma SH-SY5Y.
The European journal of neuroscience 2001;13(5):925-34.
2000: Tzima E; Walker J H
Platelet annexin V: the ins and outs.
Platelets 2000;11(5):245-51.
2000: Tzima E; Trotter P J; Orchard M A; Walker J H
Annexin V relocates to the platelet cytoskeleton upon activation and binds to a specific isoform of actin.
European journal of biochemistry / FEBS 2000;267(15):4720-30.
2000: Tzima E; Trotter P J; Hastings A D; Orchard M A; Walker J H
Investigation of the relocation of cytosolic phospholipase A2 and annexin V in activated platelets.
Thrombosis research 2000;97(6):421-9.
1999: Tzima E; Trotter P J; Orchard M A; Walker J H
Annexin V binds to the actin-based cytoskeleton at the plasma membrane of activated platelets.
Experimental cell research 1999;251(1):185-93.
1999: Danks K; Wade J A; Batten T F; Walker J H; Ball S G; Vaughan P F
Redistribution of F-actin and large dense-cored vesicles in the human neuroblastoma SH-SY5Y in response to secretagogues and protein kinase Calpha activation.
Brain research. Molecular brain research 1999;64(2):236-45.
1999: Tzima E; Poujol C; Nurden P; Nurden A T; Orchard M A; Walker J H
Annexin V relocates to the periphery of activated platelets following thrombin activation: an ultrastructural immunohistochemical approach.
Cell biology international 1999;23(9):629-35.
1998: Vaughan P F; Walker J H; Peers C
The regulation of neurotransmitter secretion by protein kinase C.
Molecular neurobiology 1998;18(2):125-55.
1998: Danks K; Walker J H; Vaughan P F
The effect of cytochalasin D and colcemid on noradrenaline release in the human neuroblastoma SH-SY5Y.
Biochemical Society transactions 1998;26(2):S111.
1998: Ou X M; Partoens P M; Wang J M; Walker J H; Danks K; Vaughan P F; De Potter W P
The storage of noradrenaline, neuropeptide Y and chromogranins in and stoichiometric release from large dense cored vesicles of the undifferentiated human neuroblastoma cell line SH-SY5Y.
International journal of molecular medicine 1998;1(1):105-12.
1998: Luckcuck T; Trotter P J; Walker J H
Localization of annexin VI in the adult and neonatal heart.
Cell biology international 1998;22(3):199-205.
1997: Trotter P J; Orchard M A; Walker J H
Relocation of annexin V to platelet membranes is a phosphorylation-dependent process.
The Biochemical journal 1997;328 ( Pt 2)():447-52.
1997: Tzima E; Collins A D; Orchard M A; Trotter P J; Walker J H
The platelet cytoskeletal-membrane interface as a target for annexin V.
Biochemical Society transactions 1997;25(4):S596.
1997: Caswell A M; Mohiti J; Walker J H
Nuclear annexin V expression and bone cell proliferation.
Biochemical Society transactions 1997;25(4):S582.
1997: Luckcuck T; Trotter P J; Walker J H
Localization of annexin V in the adult and neonatal heart.
Biochemical and biophysical research communications 1997;238(2):622-8.
1997: Mohiti J; Caswell A M; Walker J H
The nuclear location of annexin V in the human osteosarcoma cell line MG-63 depends on serum factors and tyrosine kinase signaling pathways.
Experimental cell research 1997;234(1):98-104.
1997: Goodall A R; Danks K; Walker J H; Ball S G; Vaughan P F
Occurrence of two types of secretory vesicles in the human neuroblastoma SH-SY5Y.
Journal of neurochemistry 1997;68(4):1542-52.
1997: Goodall A R; Turner N A; Walker J H; Ball S G; Vaughan P F
Activation of protein kinase C-alpha and translocation of the myristoylated alanine-rich C-kinase substrate correlate with phorbol ester-enhanced noradrenaline release from SH-SY5Y human neuroblastoma cells.
Journal of neurochemistry 1997;68(1):392-401.
1996: Turner N A; Walker J H; Ball S G; Vaughan P F
Down-regulation or long-term inhibition of protein kinase C (PKC) reduces noradrenaline release evoked via either PKC-dependent or PKC-independent pathways in human SH-SY5Y neuroblastoma cells.
Neuroscience letters 1996;220(1):37-40.
1996: Davis A J; Butt J T; Walker J H; Moss S E; Gawler D J
The Ca2+-dependent lipid binding domain of P120GAP mediates protein-protein interactions with Ca2+-dependent membrane-binding proteins. Evidence for a direct interaction between annexin VI and P120GAP.
The Journal of biological chemistry 1996;271(40):24333-6.
1996: Barwise J L; Walker J H
Subcellular localization of annexin V in human foreskin fibroblasts: nuclear localization depends on growth state.
FEBS letters 1996;394(2):213-6.
1996: Danks K; Walker J H; Vaughan P F
The occurrence of noradrenaline and neuropeptide Y in large dense-cored vesicles in the human neuroblastoma SH-SY5Y.
Biochemical Society transactions 1996;24(3):428S.
1996: Goodall A R; Walker J H; Vaughan P F
Translocation of the PKC isoforms present in the human neuroblastoma, SH-SY5Y, following short-term treatment with the phorbol ester, TPA.
Biochemical Society transactions 1996;24(3):427S.
1996: Turner N A; Walker J H; Vaughan P F
The effect of down-regulation and long-term inhibition of protein kinase C on noradrenaline secretion in the neuroblastoma cell line SH-SY5Y.
Biochemical Society transactions 1996;24(3):426S.
1996: Blanchard S; Barwise J L; Gerke V; Goodall A; Vaughan P F; Walker J H
Annexins in the human neuroblastoma SH-SY5Y: demonstration of relocation of annexins II and V to membranes in response to elevation of intracellular calcium by membrane depolarisation and by the calcium ionophore A23187.
Journal of neurochemistry 1996;67(2):805-13.
1996: Turner N A; Walker J H; Ball S G; Vaughan P F
Phorbol ester-enhanced noradrenaline secretion correlates with the presence and activity of protein kinase C-alpha in human SH-SY5Y neuroblastoma cells.
Journal of neurochemistry 1996;66(6):2381-9.
1996: Barwise J L; Walker J H
Annexins II, IV, V and VI relocate in response to rises in intracellular calcium in human foreskin fibroblasts.
Journal of cell science 1996;109 ( Pt 1)():247-55.
1995: Mohiti J; Caswell A M; Walker J H
Calcium-induced relocation of annexins IV and V in the human osteosarcoma cell line MG-63.
Molecular membrane biology 1995;12(4):321-9.
1995: Trotter P J; Orchard M A; Walker J H
Ca2+ concentration during binding determines the manner in which annexin V binds to membranes.
The Biochemical journal 1995;308 ( Pt 2)():591-8.
1995: Goodall A R; Walker J H; Vaughan P F
Identification of vesicular proteins in the human neuroblastoma cell line, SH-SY5Y.
Biochemical Society transactions 1995;23(1):50S.
1995: Trotter P J; Orchard M A; Walker J H
EGTA-resistant binding of annexin V to platelet membranes can be induced by physiological calcium concentrations.
Biochemical Society transactions 1995;23(1):37S.
1995: Mohiti J; Walker J H; Caswell A M
Studies on annexins in primary cultures of human osteoblasts and in the human osteosarcoma cell line MG-63.
Biochemical Society transactions 1995;23(1):36S.
1995: Barwise J L; Walker J H
Subcellular localization of annexins in human foreskin fibroblasts.
Biochemical Society transactions 1995;23(1):35S.
1995: Luckcuck T; Orchard C H; Harrison S M; Walker J H
Subcellular localization of annexins V and VI in isolated rat ventricular myocytes and porcine left ventricle.
Biochemical Society transactions 1995;23(1):28S.
1994: Trotter P J; Orchard M A; Walker J H
Thrombin stimulates the intracellular relocation of annexin V in human platelets.
Biochimica et biophysica acta 1994;1222(2):135-40.
1994: Tagoe C E; Boustead C M; Higgins S J; Walker J H
Characterization and immunolocalization of rat liver annexin VI.
Biochimica et biophysica acta 1994;1192(2):272-80.
1994: Turner N A; Rumsby M G; Walker J H; McMorris F A; Ball S G; Vaughan P F
A role for protein kinase C subtypes alpha and epsilon in phorbol-ester-enhanced K(+)- and carbachol-evoked noradrenaline release from the human neuroblastoma SH-SY5Y.
The Biochemical journal 1994;297 ( Pt 2)():407-13.
1993: Luckcuck T; Walker J H
Annexins in porcine heart.
Biochemical Society transactions 1993;21(4):437S.
1993: Blanchard S; Walker J H; Vaughan P F
Expression of annexins in the human neuroblastoma SH-SY5Y.
Biochemical Society transactions 1993;21 ( Pt 3)(3):315S.
1993: Boustead C M; Kenny A J; Vaughan P F; Walker J H
Localization of annexins V and VI in the porcine nervous system.
Biochemical Society transactions 1993;21 ( Pt 3)(3):292S.
1993: Trotter P J; Orchard M A; Walker J H
The intracellular relocation of annexin V in response to the physiological agonist thrombin.
Biochemical Society transactions 1993;21 ( Pt 3)(3):281S.
1993: Turner N A; Walker J H; Vaughan P F
Protein kinase C subtypes associated with the regulation of noradrenaline release in human SH-SY5Y neuroblastoma cells.
Biochemical Society transactions 1993;21 ( Pt 3)(3):249S.
1993: Boustead C M; Brown R; Walker J H
Isolation, characterization and localization of annexin V from chicken liver.
The Biochemical journal 1993;291 ( Pt 2)():601-8.
1993: Koster J J; Boustead C M; Middleton C A; Walker J H
The sub-cellular localization of annexin V in cultured chick-embryo fibroblasts.
The Biochemical journal 1993;291 ( Pt 2)():595-600.
1993: Bewley M C; Boustead C M; Walker J H; Waller D A; Huber R
Structure of chicken annexin V at 2.25-A resolution.
Biochemistry 1993;32(15):3923-9.
1992: Walker J H; Boustead C M; Koster J J; Bewley M; Waller D A
Annexin V, a calcium-dependent phospholipid-binding protein.
Biochemical Society transactions 1992;20(4):828-33.
1991: Boustead C M; Walker J H; Kennedy D; Waller D A
Crystallization and preliminary X-ray studies of annexin IV (endonexin), a calcium-dependent phospholipid-binding protein.
FEBS letters 1991;279(2):187-9.
1990: Walker J H; Boustead C M; Brown R; Koster J J; Middleton C A
Tissue and subcellular distribution of endonexin, a calcium-dependent phospholipid-binding protein.
Biochemical Society transactions 1990;18(6):1235-6.
1990: Woolgar J A; Boustead C M; Walker J H
Characterization of annexins in mammalian brain.
Journal of neurochemistry 1990;54(1):62-71.
1990: Geisow M J; Ali S M; Boustead C; Burgoyne R D; Taylor W R; Walker J H
Structures and functions of a supergene family of calcium and phospholipid binding proteins.
Progress in clinical and biological research 1990;349():111-21.
1988: Boustead C M; Walker J H; Geisow M J
Isolation and characterization of two novel calcium-dependent phospholipid-binding proteins from bovine lung.
FEBS letters 1988;233(2):233-8.
1987: Walker J H; Agoston D V
The synaptic vesicle and the cytoskeleton.
The Biochemical journal 1987;247(2):249-58.
1987: Geisow M J; Walker J H; Boustead C; Taylor W
Localization and structure of novel calcium-regulated phospholipid-binding proteins.
Biochemical Society transactions 1987;15(5):800-2.
1987: Geisow M J; Walker J H; Boustead C; Taylor W
Annexins--new family of Ca2+-regulated-phospholipid binding protein.
Bioscience reports 1987;7(4):289-98.
1986: Agoston D V; Dowe G H; Fiedler W; Giompres P E; Roed I S; Walker J H; Whittaker V P; Yamaguchi T
A kinetic study of stimulus-induced vesicle recycling in electromotor nerve terminals using labile and stable vesicle markers.
Journal of neurochemistry 1986;47(5):1584-92.
1985: Walker J H; Boustead C M; Witzemann V; Shaw G; Weber K; Osborn M
Cytoskeletal proteins at the cholinergic synapse: distribution of desmin, actin, fodrin, neurofilaments, and tubulin in Torpedo electric organ.
European journal of cell biology 1985;38(1):123-33.
1984: Walker J H; Boustead C M; Witzemann V
The 43-K protein, v1, associated with acetylcholine receptor containing membrane fragments is an actin-binding protein.
The EMBO journal 1984;3(10):2287-90.
1984: Südhof T C; Ebbecke M; Walker J H; Fritsche U; Boustead C
Isolation of mammalian calelectrins: a new class of ubiquitous Ca2+-regulated proteins.
Biochemistry 1984;23(6):1103-9.

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