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John Walker

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John R Walker; James Watson; Gus Welzel; Tove tuntland; Hugo D Urbina; Alana Althage; Juliano Alves; Jennifer L Harris; Laura H Jacobson; Bo Liu; Daniel Mason; Weijia Ou; Reynand Pacoma; Eric C Peters; Andrew M Schumacher
Enhanced proteolytic clearance of plasma Aβ by peripherally administered neprilysin does not result in reduced levels of brain Aβ in mice.
Sungeun Kim; Anthony P Orth; Diana Graus Porta; Ghislain M C Bonamy; Anna Dubrovska; Jimmy Elliott; Carlos Garcia-Echeverria; Kathryn B Grandinetti; Richard J Salamone; John R Walker; Venkateshwar A Reddy
FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.
Anna Dubrovska; A Hartung; Venkateshwar A Reddy; Laure C Bouchez; Charles Y Cho; John R Walker; Peter G Schultz
CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling.

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All Publications

2013: John R Walker; James Watson; Gus Welzel; Tove tuntland; Hugo D Urbina; Alana Althage; Juliano Alves; Jennifer L Harris; Laura H Jacobson; Bo Liu; Daniel Mason; Weijia Ou; Reynand Pacoma; Eric C Peters; Andrew M Schumacher
Enhanced proteolytic clearance of plasma Aβ by peripherally administered neprilysin does not result in reduced levels of brain Aβ in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(6):2457-64.
2013: Sungeun Kim; Anthony P Orth; Diana Graus Porta; Ghislain M C Bonamy; Anna Dubrovska; Jimmy Elliott; Carlos Garcia-Echeverria; Kathryn B Grandinetti; Richard J Salamone; John R Walker; Venkateshwar A Reddy
FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.
PloS one 2013;8(1):e51671.
2012: Anna Dubrovska; A Hartung; Venkateshwar A Reddy; Laure C Bouchez; Charles Y Cho; John R Walker; Peter G Schultz
CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling.
British journal of cancer 2012;107(1):43-52.
2011: Catherine Vilchèze; John R Walker; Michelle H. Larsen; Yossef Av-Gay; S Whitney Barnes; Richard J Glynne; William R. Jacobs Jr.
Coresistance to isoniazid and ethionamide maps to mycothiol biosynthetic genes in Mycobacterium bovis.
Antimicrobial agents and chemotherapy 2011;55(9):4422-3.
2011: Jun Liu; Ken Muneoka; Nicholas Ng; Victoria Piamonte; Sheng Ding; Richard Glynne; Mindy H Hsieh; Kristen Johnson; Jie Li; Brian M Steffy; John R Walker; Xu Wu; Jay Zhang; Peter G Schultz
Regenerative phenotype in mice with a point mutation in transforming growth factor beta type I receptor (TGFBR1).
Proceedings of the National Academy of Sciences of the United States of America 2011;108(35):14560-5.
2011: K B Grandinetti; S Ha; E C Peters; R J Salamone; T A Stevens; Daniel G Tenen; John R Walker; J Zhang; S Agarwalla; Venkateshwar A Reddy
Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα.
Oncogene 2011;30(30):3328-35.
2011: Tae-gyu Nam; Jongkook Lee; John R Walker; Achim Brinker; Charles Y Cho; Peter G Schultz
Identification and characterization of small-molecule inducers of fetal hemoglobin.
ChemMedChem 2011;6(5):777-80.
2010: Anna Dubrovska; Jimmy Elliott; Richard J Salamone; Sungeun Kim; Lindsey J Aimone; John R Walker; James Watson; Maira Sauveur-Michel; Carlos Garcia-Echeverria; Charles Y Cho; Venkateshwar A Reddy; Peter G Schultz
Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(23):5692-702.
2010: Anthony E Boitano; Jian Wang; Russell Romeo; Laure C Bouchez; Albert E Parker; Sue E Sutton; John R Walker; Colin A Flaveny; Gary H Perdew; Michael S Denison; Peter G Schultz; Michael P Cooke
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells.
Science (New York, N.Y.) 2010;329(5997):1345-8.
2009: Weidong Wang; John R Walker; Xia Wang; Matthew S Tremblay; Jae Wook Lee; Xu Wu; Peter G Schultz
Identification of small-molecule inducers of pancreatic beta-cell expansion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1427-32.
2009: Anna Dubrovska; Sungeun Kim; Richard J Salamone; John R Walker; Sauveur-Michel Maira; Carlos García-Echeverría; Peter G Schultz; Venkateshwar A Reddy
The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):268-73.
2008: Chunlei Wu; David L Delano; Nico Mitro; Stephen V Su; Jeff Janes; Phillip McClurg; Serge Batalov; Genevieve L Welch; Jie Zhang; Anthony P Orth; John R Walker; Richard J Glynne; Michael P Cooke; Joseph S Takahashi; Kazuhiro Shimomura; Akira Kohsaka; Joseph Bass; Enrique Saez; Timothy Wiltshire; Andrew Su
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.
PLoS genetics 2008;4(5):e1000070.
2007: Phillip McClurg; Jeff Janes; Chunlei Wu; David L Delano; John R Walker; Serge Batalov; Joseph S Takahashi; Kazuhiro Shimomura; Akira Kohsaka; Joseph Bass; Timothy Wiltshire; Andrew Su
Genomewide association analysis in diverse inbred mice: power and population structure.
Genetics 2007;176(1):675-83.
2007: Yanxia Liu; Jonathan T Kern; John R Walker; Jeffrey A Johnson; Peter G Schultz; Hendrik Luesch
A genomic screen for activators of the antioxidant response element.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5205-10.
2006: Hendrik Luesch; Sumit K Chanda; R Marina Raya; Paul D DeJesus; Anthony P Orth; John R Walker; Juan Carlos Izpisúa Belmonte; Peter G Schultz
A functional genomics approach to the mode of action of apratoxin A.
Nature chemical biology 2006;2(3):158-67.
2004: Nathalie Spielewoy; Karin Flick; Tatyana I Kalashnikova; John R Walker; Curt Wittenberg
Regulation and recognition of SCFGrr1 targets in the glucose and amino acid signaling pathways.
Molecular and cellular biology 2004;24(20):8994-9005.
2004: Andrew Su; Timothy Wiltshire; Serge Batalov; Hilmar Lapp; Keith A Ching; David Block; Jie Zhang; Richard Soden; Mimi Hayakawa; Gabriel Kreiman; Michael P Cooke; John R Walker; John B Hogenesch
A gene atlas of the mouse and human protein-encoding transcriptomes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):6062-7.
2004: John R Walker; Andrew Su; David W Self; John B Hogenesch; Hilmar Lapp; Rainer Maier; Daniel Hoyer; Graeme Bilbe
Applications of a rat multiple tissue gene expression data set.
Genome research 2004;14(4):742-9.
2003: John R Walker; Scott A Chen; Heather Moffitt; Charles E Inturrisi; George F Koob
Chronic opioid exposure produces increased heroin self-administration in rats.
Pharmacology, biochemistry, and behavior 2003;75(2):349-54.
2003: Sheng-Hao Chao; John R Walker; Sumit K Chanda; Nathanael S Gray; Jeremy S Caldwell
Identification of homeodomain proteins, PBX1 and PREP1, involved in the transcription of murine leukemia virus.
Molecular and cellular biology 2003;23(3):831-41.
2002: John R Walker; Lars Terenius; George F Koob
Conditioned opioid withdrawal decreases nociceptin/orphanin FQ levels in the frontal cortex and olfactory tubercle.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;27(2):203-11.
2002: Andrew Su; Michael P Cooke; Keith A Ching; Yaron Hakak; John R Walker; Timothy Wiltshire; Anthony P Orth; Raquel G Vega; Lisa M Sapinoso; Aziz Moqrich; Ardem Patapoutian; Garret M Hampton; Peter G Schultz; John B Hogenesch
Large-scale analysis of the human and mouse transcriptomes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4465-70.
2001: Yaron Hakak; John R Walker; C Li; W H Wong; Kenneth L Davis; Joseph Buxbaum; Vahram Haroutunian; Allen Fienberg
Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4746-51.
2000: Serge H Ahmed; John R Walker; George F Koob
Persistent increase in the motivation to take heroin in rats with a history of drug escalation.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(4):413-21.
2000: John R Walker; Serge H Ahmed; KN Gracy; George F Koob
Microinjections of an opiate receptor antagonist into the bed nucleus of the stria terminalis suppress heroin self-administration in dependent rats.
Brain research 2000;854(1-2):85-92.
1999: John R Walker; M King; Emanuela Izzo; George F Koob; Gavril W Pasternak
Antagonism of heroin and morphine self-administration in rats by the morphine-6beta-glucuronide antagonist 3-O-methylnaltrexone.
European journal of pharmacology 1999;383(2):115-9.
1998: John R Walker; M Spina; Lars Terenius; George F Koob
Nociceptin fails to affect heroin self-administration in the rat.
Neuroreport 1998;9(10):2243-7.
1997: John R Walker; George F Koob
Orphan anxiety.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14217-9.